Dubey: Review of Neospora caninum and neosporosis in animals
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Estimating Neospora caninum prevalence in wildlife populations using Bayesian inference
Karla Moreno‐Torres, Barbara Wolfe, William Saville, Rebecca Garabed
Ecology and Evolution.2016; 6(7): 2216.     CrossRef
Identification of antigenic proteins from Neospora caninum recognized by bovine immunoglobulins M, E, A and G using immunoproteomics
Yong‐seung Shin, Eung‐goo Lee, Gee‐wook Shin, Young‐rim Kim, Eun‐young Lee, Jae‐hoon Kim, Hwan Jang, Laurel J. Gershwin, Dae‐yong Kim, Yong‐hwan Kim, Gon‐sup Kim, Myung‐deuk Suh, Tae‐sung Jung
PROTEOMICS.2004; 4(11): 3600.     CrossRef
Prevalence of intestinal parasites in street dogs (Canis lupus familiaris) with highlights on zoonosis in Lalitpur, Nepal
Roshan Babu Adhikari, Madhuri Adhikari Dhakal, Tirth Raj Ghimire
Veterinary Medicine and Science.2023; 9(6): 2513.     CrossRef
First molecular detection of Neospora caninum from naturally infected slaughtered camels in Tunisia
Yosra Amdouni, Imen abedennebi, Safa Amairia, Amara Abdelkader, Walid Chandoul, Mohamed Gharbi
Veterinary Medicine and Science.2022; 8(5): 2241.     CrossRef
Blocking ELISA Using Recombinant NcSRS2 Protein for Diagnosing Bovine Neosporosis
Francine A. Sinnott, Leonardo G. Monte, Thais F. Collares, Bruno M. De Matos, Diene B. Pacheco, Sibele Borsuk, Renato Andreotti, Cláudia P. Hartleben
Current Microbiology.2015; 70(3): 429.     CrossRef
Prevalence of Neospora caninum infection in Sardinian dairy farms (Italy) detected by iscom ELISA on tank bulk milk
A. Varcasia, G. Capelli, A. Ruiu, M. Ladu, A. Scala, C. Bjorkman
Parasitology Research.2006; 98(3): 264.     CrossRef
Seroprevalence of Neospora caninum and Toxoplasma gondii in camels (Camelus dromedarius) in Mashhad, Iran
A. Sadrebazzaz, H. Haddadzadeh, P. Shayan
Parasitology Research.2006; 98(6): 600.     CrossRef
Immune responses during pregnancy in heifers naturally infected with Neospora caninum with and without immunization
Aur�lie G. Andrianarivo, Mark L. Anderson, Joan D. Rowe, Ian A. Gardner, James P. Reynolds, Leszek Choromanski, Patricia A. Conrad
Parasitology Research.2005; 96(1): 24.     CrossRef
Humoral immune reaction of newborn calves congenitally infected with Neospora caninum and experimentally treated with toltrazuril
Corinne Haerdi, Michael Haessig, Heinz Sager, Gisela Greif, Daniela Staubli, Bruno Gottstein
Parasitology Research.2006; 99(5): 534.     CrossRef
Survey of Neospora caninum and bovine herpes virus 1 coinfection in cattle
L. Rinaldi, F. Pacelli, G. Iovane, U. Pagnini, V. Veneziano, G. Fusco, G. Cringoli
Parasitology Research.2007; 100(2): 359.     CrossRef
Seroprevalence of Neospora caninum infection in dogs from rural and urban environments in Tehran, Iran
H. R. Haddadzadeh, A. Sadrebazzaz, A. Malmasi, H. Talei Ardakani, P. Khazraii Nia, N. Sadreshirazi
Parasitology Research.2007; 101(6): 1563.     CrossRef
Toltrazuril treatment of congenitally acquired Neospora caninum infection in newborn mice
M. Strohbusch, N. Müller, A. Hemphill, R. Krebber, G. Greif, B. Gottstein
Parasitology Research.2009; 104(6): 1335.     CrossRef
First identification of Neospora caninum by PCR in aborted bovine foetuses in Romania
Ovidiu Şuteu, Adriana Titilincu, David Modrý, Andrei Mihalca, Viorica Mircean, Vasile Cozma
Parasitology Research.2010; 106(3): 719.     CrossRef
Investigation of Neospora caninum, Hammondia sp., and Toxoplasma gondii in tissues from slaughtered beef cattle in Bahia, Brazil
Sara Lima Santos, Kattyanne de Souza Costa, Leane Queiroz Gondim, Mariana Sampaio Anares da Silva, Rosângela Soares Uzêda, Kiyoko Abe-Sandes, Luís Fernando Pita Gondim
Parasitology Research.2010; 106(2): 457.     CrossRef
A survey of Neospora caninum-associated bovine abortion in large dairy farms of Mashhad, Iran
G R Razmi, H Zarea, Z Naseri
Parasitology Research.2010; 106(6): 1419.     CrossRef
Prevalence of antibodies to Neospora caninum in stray dogs of Urmia, Iran
Mohammad Yakhchali, Shahram Javadi, Ahmad Morshedi
Parasitology Research.2010; 106(6): 1455.     CrossRef
Detection of Toxoplasma gondii, Neospora caninum, and Encephalitozoon cuniculi in the brains of common voles (Microtus arvalis) and water voles (Arvicola terrestris) by gene amplification techniques in western Austria (Vorarlberg)
Hans-Peter Fuehrer, Ingrid Blöschl, Christian Siehs, Andreas Hassl
Parasitology Research.2010; 107(2): 469.     CrossRef
Neospora spp. and Toxoplasma gondii antibodies in horses in the Czech Republic
Eva Bártová, Kamil Sedlák, Michaela Syrová, Ivan Literák
Parasitology Research.2010; 107(4): 783.     CrossRef
Prevalence of antibodies against Neospora caninum in dogs from urban areas in Central Poland
Katarzyna Goździk, Robert Wrzesień, Adrianna Wielgosz-Ostolska, Justyna Bień, Monika Kozak-Ljunggren, Władysław Cabaj
Parasitology Research.2011; 108(4): 991.     CrossRef
Transplacental transmission in cattle: is Toxoplasma gondii less potent than Neospora caninum?
Jitbanjong Wiengcharoen, R. C. Andrew Thompson, Chawalit Nakthong, Parntep Rattanakorn, Yaowalark Sukthana
Parasitology Research.2011; 108(5): 1235.     CrossRef
Evidence of congenital transmission of Neospora caninum in naturally infected water buffalo (Bubalus bubalis) fetus from Brazil
Andreas L. Chryssafidis, Rodrigo M. Soares, Aline A. R. Rodrigues, Nelcio A. T. Carvalho, Solange Maria Gennari
Parasitology Research.2011; 108(3): 741.     CrossRef
Comparative study of protective activities of Neospora caninum bradyzoite antigens, NcBAG1, NcBSR4, NcMAG1, and NcSAG4, in a mouse model of acute parasitic infection
Masaki Uchida, Kotomi Nagashima, Yui Akatsuka, Takashi Murakami, Akira Ito, Soichi Imai, Kazunori Ike
Parasitology Research.2013; 112(2): 655.     CrossRef
Neospora caninum NC-6 Argentina induces fetopathy in both serologically positive and negative experimentally inoculated pregnant dams
D. Bacigalupe, W. Basso, S. G. Caspe, G. Moré, L. Lischinsky, M. L. Gos, M. Leunda, L. Campero, D. P. Moore, G. Schares, C. M. Campero, M. C. Venturini
Parasitology Research.2013; 112(7): 2585.     CrossRef
Pathogenicity of Nc-Bahia and Nc-1 strains of Neospora caninum in experimentally infected cows and buffaloes in early pregnancy
Andreas Lazaros Chryssafidis, Germán Cantón, Francesca Chianini, Elisabeth A. Innes, Ed Hoffmann Madureira, Solange Maria Gennari
Parasitology Research.2014; 113(4): 1521.     CrossRef
Abortion and foetal lesions induced by Neospora caninum in experimentally infected water buffalos (Bubalus bubalis)
Andreas L. Chryssafidis, Germán Cantón, Francesca Chianini, Elisabeth A. Innes, Ed H. Madureira, Rodrigo M. Soares, Solange M. Gennari
Parasitology Research.2015; 114(1): 193.     CrossRef
Identification and characterization of a microneme protein (NcMIC6) in Neospora caninum
Wensheng Li, Jing Liu, Jing Wang, Yong Fu, Huizhu Nan, Qun Liu
Parasitology Research.2015; 114(8): 2893.     CrossRef
Herd-level prevalence and associated risk factors for Toxoplasma gondii, Neospora caninum, Chlamydia abortus and bovine viral diarrhoea virus in commercial dairy and beef cattle in eastern, northern and northeastern China
Wu-Wen Sun, Qing-Feng Meng, Wei Cong, Xiao-Feng Shan, Chun-Feng Wang, Ai-Dong Qian
Parasitology Research.2015; 114(11): 4211.     CrossRef
Toxoplasma gondii and Neospora caninum induce different host cell responses at proteome-wide phosphorylation events; a step forward for uncovering the biological differences between these closely related parasites
Mariwan M. M. Al-Bajalan, Dong Xia, Stuart Armstrong, Nadine Randle, Jonathan M. Wastling
Parasitology Research.2017; 116(10): 2707.     CrossRef
Seroprevalence of Neospora caninum infection and associated risk factors in dairy cattle in Serbia
Ivana Klun, Vladimir Ćirković, Milan Maletić, Siniša Bradonjić, Olgica Djurković-Djaković
Parasitology Research.2019; 118(6): 1875.     CrossRef
Contribution of introns to the species diversity associated with the apicomplexan parasite, Neospora caninum
Larissa Calarco, John Ellis
Parasitology Research.2020; 119(2): 431.     CrossRef
Besnoitia besnoiti–driven endothelial host cell cycle alteration
Zahady D. Velásquez, Sara Lopez-Osorio, Learta Pervizaj-Oruqaj, Susanne Herold, Carlos Hermosilla, Anja Taubert
Parasitology Research.2020; 119(8): 2563.     CrossRef
Function of Neospora caninum dense granule protein 7 in innate immunity in mice
Fei Wang, Xianmei Wang, Xingju Song, Lei Ma, Jing Yang, Qun Liu, Jing Liu
Parasitology Research.2021; 120(1): 197.     CrossRef
Differential acute-phase protein responses in dogs seropositive or seronegative for Neospora caninum
Rafaela Furioso Ferreira, Rosangela Locatelli Dittrich, Isabelle Bay Zimmermann, Blanka Beer Ljubic, Vladimir Mrljak, Peter David Eckersall
Parasitology Research.2021; 120(10): 3529.     CrossRef
Neospora caninum, a cause of abortion in donkeys (Equus asinus) in Iran
Seyedeh Shabnam Rahmani, Farnaz Malekifard, Mousa Tavassoli
Parasitology Research.2022; 121(1): 367.     CrossRef
Prevalence of Neospora caninum antibodies in fattening pigs and sows from intensive farms in northern Italy
Luca Villa, Alessia Libera Gazzonis, Carolina Allievi, Sergio Aurelio Zanzani, Michele Mortarino, Maria Teresa Manfredi
Parasitology Research.2022; 121(3): 1033.     CrossRef
Molecular detection and phylogenic characterization of Neospora caninum in naturally infected sheep in Alborz and Qazvin provinces, the north of the central region of Iran
Shahla Karimi, Vahid Nasiri, Farnoosh Jameie, Bahar Shemshadi, Habibullah Paykari
Parasitology Research.2023; 122(12): 2907.     CrossRef
Serological and molecular detection of Toxoplasma gondii and Neospora caninum in free-ranging rats from Nagpur, India
Veena Mishra, Pallabi Mitra, Shruti Barbuddhe, Yogesh Thorat, Kailas Chavan, Shilpshri Shinde, Sandeep Chaudhari, Waqar Khan, Abhijit S. Deshmukh
Parasitology Research.2024;[Epub]     CrossRef
Serological and molecular detection of Toxoplasma gondii and Neospora caninum in ruminants from Somalia
Monica T. A. Kakimori, Aamir M. Osman, Ana C. S. Silva, Abdalla M. Ibrahim, Mohamed A. Shair, Ana C. Cavallieri, Luiz D. Barros, João L. Garcia, Thállitha S. W. J. Vieira, Ahmed A. Hassan-Kadle, Rafael F. C. Vieira
Parasitology Research.2024;[Epub]     CrossRef
Clinical neosporosis in three dogs in Shahrekord, Iran
Morteza Hosseininejad, Abdolali Malmasi
Comparative Clinical Pathology.2010; 19(3): 315.     CrossRef
Seroprevalence of Neospora caninum infection in dogs in Chaharmahal-va-Bakhtiari Province, Iran
M. Hosseininejad, F. Hosseini, M. Mahzounieh, A. Raisi Nafchi, M. Mosharraf
Comparative Clinical Pathology.2010; 19(3): 269.     CrossRef
The first report of Neospora caninum prevalence in aborted and healthy sheep from west of Iran
Behrouz Ezatpour, Masoud Alirezaei, Ali Hassanvand, Mohammad Zibaei, Mojgan Azadpour, Farzad Ebrahimzadeh
Comparative Clinical Pathology.2015; 24(1): 19.     CrossRef
Snake neosporosis: molecular detection and phylogenic characterization of Neospora caninum DNA from Iranian venomous snakes
Vahid Nasiri, Farnoosh Jameie
European Journal of Wildlife Research.2023;[Epub]     CrossRef
Effect of Urbanization on Neospora caninum Seroprevalence in White-Tailed Deer (Odocoileus virginianus)
Gregory A. Ballash, Mark C. Jenkins, O. C. H. Kwok, J. P. Dubey, Abigail B. Shoben, Terry L. Robison, Tom Kraft, Erik E. Shaffer, Patricia M. Dennis
EcoHealth.2019; 16(1): 109.     CrossRef
Planning and Animal Welfare Law: Considering Why Planning Authorities in the Republic of Ireland Should have Regard to Animal Welfare Laws as Part of the Planning Process
Michelle Strauss
Liverpool Law Review.2020; 41(2): 129.     CrossRef
First report of Neospora caninum infection in cattle in Sudan
Amira Mohamed Elhassan Ibrahim, Abdelghafar Mohamed Elfahal, Abdel Rahim Mohamed El Hussein
Tropical Animal Health and Production.2012; 44(4): 769.     CrossRef
Effect of natural neosporosis on bull sperm quality
Somayeh Bahrami, Hossein Hamidinejat, Seyed Reza Fatemi-Tabatabaei, Saeed Sardarifar
Tropical Animal Health and Production.2018; 50(1): 85.     CrossRef
Estimating the total economic costs of Neospora caninum infections in dairy cows in Turkey
Pınar Ayvazoğlu Demir, Funda Eşki, Armağan E. Ütük
Tropical Animal Health and Production.2020; 52(6): 3251.     CrossRef
Generation and infection of bovine PBMC-derived dendritic cells with Neospora caninum
G. Grandi, C. Genchi, C. Bazzocchi, M. Mortarino, P. Borghetti, E. De Angelis, L. H. Kramer
Veterinary Research Communications.2008; 32(S1): 207.     CrossRef
Occurrence of antibodies and epidemiological significance of Toxoplasma Gondii and Neospora caninum infections in canine populations of Laguna, State of Santa Catarina
Ana Paula Remor-Sebolt, Felipe Rieth de Lima, Larissa Américo, Mayckon Antônio Cardoso Padilha, Andreas Lazaros Chryssafidis, Anderson Barbosa de Moura
Veterinary Research Communications.2024; 48(5): 3349.     CrossRef
Cloning and expression of Neospora caninum dense-granule 7 in E. coli
Marziye Kefayat, Hossein Hamidinejat, Masoud Reza Seifiabadshapoori, Mohammad Mehdi Namavari, Parviz Shayan, Saad Gooraninejad
Journal of Parasitic Diseases.2014; 38(2): 196.     CrossRef
Neospora caninum infection in Iran (2004–2020): A review
Jamal Gharekhani, Mohammad Yakhchali, Reza Berahmat
Journal of Parasitic Diseases.2020; 44(4): 671.     CrossRef
Seroprevalence of Neospora caninum and Toxoplasma gondii IgG and IgM antibodies among buffaloes and cattle from Menoufia Province, Egypt
Hany M. Ibrahim, Adel A. H. Abdel-Rahman, Nora M. Bishr
Journal of Parasitic Diseases.2021; 45(4): 952.     CrossRef
Seroprevalence of Neospora caninum antibodies in dogs, cows, and humans in Assiut province, Egypt: a pilot study
Maha I. Hamed, Mostafa F. N. Abushahba, Ahmed Gareh, Abdelbaset E. Abdelbaset
Journal of Parasitic Diseases.2023; 47(3): 677.     CrossRef
Neospora caninum antibodies in bulk tank milk from dairy cattle herds in Italy in relation to reproductive and productive parameters and spatial analysis
Luca Villa, Carolina Allievi, Anna Rita Di Cerbo, Sergio Aurelio Zanzani, Flavio Sommariva, Lucio Zanini, Michele Mortarino, Maria Teresa Manfredi
Acta Tropica.2024; 254: 107194.     CrossRef
A first insight into seropositivity of Neospora caninum and associated risk factors in free-roaming dogs from Ecuador
Angel Sebastian Rodriguez-Pazmiño, Carla M. Brito, Mauricio Salas-Rueda, Solon Alberto Orlando, Miguel Angel Garcia-Bereguiain
Acta Tropica.2024; 256: 107245.     CrossRef
Fetal death: comparative aspects in large domestic animals
F.H Jonker
Animal Reproduction Science.2004; 82-83: 415.     CrossRef
Pathogen exposure in endangered island fox (Urocyon littoralis) populations: Implications for conservation management
Deana L. Clifford, Jonna A.K. Mazet, Edward J. Dubovi, David K. Garcelon, Timothy J. Coonan, Patricia A. Conrad, Linda Munson
Biological Conservation.2006; 131(2): 230.     CrossRef
Serum levels of nitric oxide and protein oxidation in goats seropositive for Toxoplasma gondii and Neospora caninum
A.A. Tonin, A. Weber, A. Ribeiro, G. Camillo, F.F. Vogel, A.B. Moura, G.V. Bochi, R.N. Moresco, A.S. Da Silva
Comparative Immunology, Microbiology and Infectious Diseases.2015; 41: 55.     CrossRef
Molecular assessment of the transplacental transmission of Toxoplasma gondii , Neospora caninum , Brucella canis and Ehrlichia canis in dogs
Isis Indaiara Gonçalves Granjeiro Taques, Tatiane Rodrigues Barbosa, Andresa de Cássia Martini, Letícia Camara Pitchenin, Ísis Assis Braga, Andréia Lima Tomé de Melo, Luciano Nakazato, Valéria Dutra, Daniel Moura de Aguiar
Comparative Immunology, Microbiology and Infectious Diseases.2016; 49: 47.     CrossRef
Molecular detection and phylogenetic analysis of Neospora caninum in various hosts from Iran
Jamal Gharekhani, Mohammad Yakhchali, Reza Heidari
Comparative Immunology, Microbiology and Infectious Diseases.2022; 80: 101737.     CrossRef
Investigation of Toxoplasma gondii, Neospora caninum and Tritrichomonas foetus in abortions of cattle, sheep and goats in Turkey: Analysis by real-time PCR, conventional PCR and histopathological methods
Bunyamin Irehan, Ayse Sonmez, Muge Metin Atalay, Aysel Itik Ekinci, Figen Celik, Nalan Durmus, Ayse Turkan Ciftci, Sami Simsek
Comparative Immunology, Microbiology and Infectious Diseases.2022; 89: 101867.     CrossRef
The seasonality as a relevant aspect to be considered for differential diagnosis of Trypanosoma vivax infection and co-infections in female cattle
Izabela Andrade Pandolfi, Wallacy Augusto de Oliveira, Olindo Assis Martins-Filho, Fernanda Fortes de Araújo, Ismael Artur da Costa Rocha, Eustáquio Resende Bittar, Marcio Sobreira Silva Araújo, Joely Ferreira Figueiredo Bittar
Comparative Immunology, Microbiology and Infectious Diseases.2024; 109: 102180.     CrossRef
Neosporosis in Cattle
J.P. Dubey
Veterinary Clinics of North America: Food Animal Practice.2005; 21(2): 473.     CrossRef
Neosporosis, Toxoplasmosis, and Sarcocystosis in Ruminants
J.P. Dubey, David S. Lindsay
Veterinary Clinics of North America: Food Animal Practice.2006; 22(3): 645.     CrossRef
Toxoplasmosis and Other Intestinal Coccidial Infections in Cats and Dogs
J.P. Dubey, David S. Lindsay, Michael R. Lappin
Veterinary Clinics of North America: Small Animal Practice.2009; 39(6): 1009.     CrossRef
Molecular analyses on Neospora caninum -triggered NETosis in the caprine system
R. Villagra-Blanco, L.M.R. Silva, U. Gärtner, H. Wagner, K. Failing, A. Wehrend, A. Taubert, C. Hermosilla
Developmental & Comparative Immunology.2017; 72: 119.     CrossRef
Factors affecting plasma prolactin concentrations throughout gestation in high producing dairy cows
I. García-Ispierto, F. López-Gatius, S. Almería, J. Yániz, P. Santolaria, B. Serrano, G. Bech-Sàbat, C. Nogareda, J. Sulon, N.M. de Sousa, J.F. Beckers
Domestic Animal Endocrinology.2009; 36(2): 57.     CrossRef
Neospora caninum: Antibodies directed against tachyzoite surface protein NcSRS2 inhibit parasite attachment and invasion of placental trophoblasts in vitro
Gary J. Haldorson, James B. Stanton, Bruce A. Mathison, Carlos E. Suarez, Tim V. Baszler
Experimental Parasitology.2006; 112(3): 172.     CrossRef
Neospora caninum: High susceptibility to the parasite in C57BL/10ScCr mice
A.S. Botelho, L. Teixeira, J.M. Correia-da-Costa, A.M.R. Faustino, A.G. Castro, M. Vilanova
Experimental Parasitology.2007; 115(1): 68.     CrossRef
Neospora caninum: Early immune response of rat mixed glial cultures after tachyzoites infection
A.M. Pinheiro, S.L. Costa, S.M. Freire, C.S.O. Ribeiro, M. Tardy, R.S. El-Bachá, M.F.D. Costa
Experimental Parasitology.2010; 124(4): 442.     CrossRef
Neospora caninum: Application of apical membrane antigen 1 encapsulated in the oligomannose-coated liposomes for reduction of offspring mortality from infection in BALB/c mice
Houshuang Zhang, Yoshifumi Nishikawa, Junya Yamagishi, Jinlin Zhou, Yuzuru Ikehara, Naoya Kojima, Naoaki Yokoyama, Xuenan Xuan
Experimental Parasitology.2010; 125(2): 130.     CrossRef
Neospora caninum: In vitro culture of tachyzoites in MCF-7 human breast carcinoma cells
Qiang Lv, Jianhua Li, Pengtao Gong, Shenyang Xing, Xichen Zhang
Experimental Parasitology.2010; 126(4): 536.     CrossRef
Neospora caninum: Infection induces high lysosomal activity
Alexandre M. Pinheiro, Cláudia Valle Cabral D. Santos, Luiz Erlon A. Rodrigues
Experimental Parasitology.2013; 134(4): 409.     CrossRef
Evaluation of Neospora caninum truncated dense granule protein 2 for serodiagnosis by enzyme-linked immunosorbent assay in dogs
Chunmei Jin, Longzheng Yu, Yinan Wang, Shiyue Hu, Shoufa Zhang
Experimental Parasitology.2015; 157: 88.     CrossRef
Extended-spectrum antiprotozoal bumped kinase inhibitors: A review
Wesley C. Van Voorhis, J. Stone Doggett, Marilyn Parsons, Matthew A. Hulverson, Ryan Choi, Samuel L.M. Arnold, Michael W. Riggs, Andrew Hemphill, Daniel K. Howe, Robert H. Mealey, Audrey O.T. Lau, Ethan A. Merritt, Dustin J. Maly, Erkang Fan, Kayode K. Oj
Experimental Parasitology.2017; 180: 71.     CrossRef
Peroxisome proliferator-activated receptor-γ-mediated polarization of macrophages in Neospora caninum infection
Xuexiu He, Pengtao Gong, Zhengkai Wei, Weijian Liu, Weili Wang, Jianhua Li, Zhengtao Yang, Xichen Zhang
Experimental Parasitology.2017; 178: 37.     CrossRef
Experimental infection by Neospora caninum in gerbil reduces activity of enzymes involved in energy metabolism
Aleksandro S. Da Silva, Roger R. Gebert, João H. Reis, Matheus D. Baldissera, Carine F. Souza, Luiz Daniel Barros, João L. Garcia, Anderson Gris, Ricardo E. Mendes
Experimental Parasitology.2020; 208: 107790.     CrossRef
Coyotes (Canis latrans) are definitive hosts of Neospora caninum
Luis F.P Gondim, Milton M McAllister, William C Pitt, Doris E Zemlicka
International Journal for Parasitology.2004; 34(2): 159.     CrossRef
Biologic, morphologic, and molecular characterisation of Neospora caninum isolates from littermate dogs
J.P. Dubey, C. Sreekumar, E. Knickman, K.B. Miska, M.C.B. Vianna, O.C.H. Kwok, D.E. Hill, M.C. Jenkins, D.S. Lindsay, C.E. Greene
International Journal for Parasitology.2004; 34(10): 1157.     CrossRef
Immunization with native surface protein NcSRS2 induces a Th2 immune response and reduces congenital Neospora caninum transmission in mice
G.J. Haldorson, B.A. Mathison, K. Wenberg, P.A. Conrad, J.P. Dubey, A.J. Trees, I. Yamane, T.V. Baszler
International Journal for Parasitology.2005; 35(13): 1407.     CrossRef
Natural killer cells act as early responders in an experimental infection with Neospora caninum in calves
Siv Klevar, Siri Kulberg, Preben Boysen, Anne K. Storset, Torfinn Moldal, Camilla Björkman, Ingrid Olsen
International Journal for Parasitology.2007; 37(3-4): 329.     CrossRef
Molecular characterisation of BSR4, a novel bradyzoite-specific gene from Neospora caninum
V. Risco-Castillo, A. Fernández-García, A. Zaballos, A. Aguado-Martínez, A. Hemphill, A. Rodríguez-Bertos, G. Álvarez-García, L.M. Ortega-Mora
International Journal for Parasitology.2007; 37(8-9): 887.     CrossRef
Prevention of vertical transmission of Neospora caninum in C57BL/6 mice vaccinated with Brucella abortus strain RB51 expressing N. caninum protective antigens
Sheela Ramamoorthy, Neelima Sanakkayala, Ramesh Vemulapalli, Neeta Jain, David S. Lindsay, Gerhardt S. Schurig, Stephen M. Boyle, Nammalwar Sriranganathan
International Journal for Parasitology.2007; 37(13): 1531.     CrossRef
In vitro screening of the open source Pathogen Box identifies novel compounds with profound activities against Neospora caninum
Joachim Müller, Adriana Aguado, Benoît Laleu, Vreni Balmer, Dominic Ritler, Andrew Hemphill
International Journal for Parasitology.2017; 47(12): 801.     CrossRef
Advances in the diagnosis of bovine besnoitiosis: current options and applications for control
Daniel Gutiérrez-Expósito, Ignacio Ferre, Luis M. Ortega-Mora, Gema Álvarez-García
International Journal for Parasitology.2017; 47(12): 737.     CrossRef
Buparvaquone is active against Neospora caninum in vitro and in experimentally infected mice
Joachim Müller, Adriana Aguado-Martinez, Vera Manser, Vreni Balmer, Pablo Winzer, Dominic Ritler, Isabel Hostettler, David Arranz-Solís, Luis Ortega-Mora, Andrew Hemphill
International Journal for Parasitology: Drugs and Drug Resistance.2015; 5(1): 16.     CrossRef
A review of neosporosis and pathologic findings of Neospora caninum infection in wildlife
Shannon L. Donahoe, Scott A. Lindsay, Mark Krockenberger, David Phalen, Jan Šlapeta
International Journal for Parasitology: Parasites and Wildlife.2015; 4(2): 216.     CrossRef
Bottlenose dolphins (Tursiops truncatus) do also cast neutrophil extracellular traps against the apicomplexan parasite Neospora caninum
R. Villagra-Blanco, L.M.R. Silva, A. Aguilella-Segura, I. Arcenillas-Hernández, C. Martínez-Carrasco, A. Seipp, U. Gärtner, R. Ruiz de Ybañez, A. Taubert, C. Hermosilla
International Journal for Parasitology: Parasites and Wildlife.2017; 6(3): 287.     CrossRef
Tracking Neospora caninum parasites using chimera monoclonal antibodies against its surface antigen-related sequences (rNcSRS2)
Jinhua Dong, Takahiro Otsuki, Tatsuya Kato, Enoch Y. Park
Journal of Bioscience and Bioengineering.2014; 117(3): 351.     CrossRef
Pathogenesis of Bovine Neosporosis
J.P. Dubey, D. Buxton, W. Wouda
Journal of Comparative Pathology.2006; 134(4): 267.     CrossRef
Neospora caninum: the First Demonstration of the Enteroepithelial Stages in the Intestines of a Naturally Infected Dog
O. Kul, H.T. Atmaca, T. Anteplioglu, N. Ocal, S. Canpolat
Journal of Comparative Pathology.2015; 153(1): 9.     CrossRef
Risk Factors for Occurrence of Anti-Neospora spp. Antibodies in Horses From Alagoas, Brazil
Sandra Regina Fonseca de Araújo Valença, Rômulo Menna Barreto Valença, José Wilton Pinheiro Junior, Pedro Paulo Feitosa de Albuquerque, Orestes Luiz Souza Neto, Rinaldo Aparecido Mota
Journal of Equine Veterinary Science.2015; 35(11-12): 917.     CrossRef
Genetic diversity amongst isolates of Neospora caninum, and the development of a multiplex assay for the detection of distinct strains
S. Al-Qassab, M.P. Reichel, A. Ivens, J.T. Ellis
Molecular and Cellular Probes.2009; 23(3-4): 132.     CrossRef
A second generation multiplex PCR for typing strains of Neospora caninum using six DNA targets
Sarwat Al-Qassab, Michael P. Reichel, John Ellis
Molecular and Cellular Probes.2010; 24(1): 20.     CrossRef
Relation between Neospora caninum and abortion in dairy cows: Risk factors and pathogenesis of disease
Vanderlei Klauck, Gustavo Machado, Rafael Pazinato, Willian M. Radavelli, Daiane S. Santos, Jean Carlo Berwaguer, Patricia Braunig, Fernanda F. Vogel, Aleksandro S. Da Silva
Microbial Pathogenesis.2016; 92: 46.     CrossRef
A GFP-based motif-trap reveals a novel mechanism of targeting for the Toxoplasma ROP4 protein
Peter J. Bradley, Nancy Li, John C. Boothroyd
Molecular and Biochemical Parasitology.2004; 137(1): 111.     CrossRef
From dog to man: The broad spectrum of inflammatory myopathies
G. Diane Shelton
Neuromuscular Disorders.2007; 17(9-10): 663.     CrossRef
Toxoplasma gondii and Neospora caninum infections in goat abortions from Argentina
J.M. Unzaga, G. Moré, D. Bacigalupe, M. Rambeaud, L. Pardini, A. Dellarupe, L. De Felice, M.L. Gos, M.C. Venturini
Parasitology International.2014; 63(6): 865.     CrossRef
Genetic diversity of bovine Neospora caninum determined by microsatellite markers
N. Salehi, B. Gottstein, H.R. Haddadzadeh
Parasitology International.2015; 64(5): 357.     CrossRef
Effects of Thai piperaceae plant extracts on Neospora caninum infection
Arpron Leesombun, Sookruetai Boonmasawai, Yoshifumi Nishikawa
Parasitology International.2017; 66(3): 219.     CrossRef
Neospora caninum in birds: A review
Luiz Daniel de Barros, Ana Carolina Miura, Ana Flávia Minutti, Odilon Vidotto, João Luis Garcia
Parasitology International.2018; 67(4): 397.     CrossRef
Identification of the antigenic region of Neospora caninum dense granule protein 7 using ELISA
Hanan H. Abdelbaky, Ragab M. Fereig, Yoshifumi Nishikawa
Parasitology International.2018; 67(6): 675.     CrossRef
Seroprevalence of Cryptosporidium parvum and Neospora caninum in cattle in the southern Kyushu region of Japan
Tatsunori Masatani, Ragab M. Fereig, Konosuke Otomaru, Shingo Ishikawa, Isshu Kojima, Seiji Hobo, Yoshifumi Nishikawa
Parasitology International.2018; 67(6): 763.     CrossRef
Evaluation of Neospora caninum serodiagnostic antigens for bovine neosporosis
Hanan H. Abdelbaky, Maki Nishimura, Naomi Shimoda, Jun Hiasa, Ragab M. Fereig, Hiromi Tokimitsu, Hisashi Inokuma, Yoshifumi Nishikawa
Parasitology International.2020; 75: 102045.     CrossRef
Validation of a commercially available cELISA test for canine neosporosis against an indirect fluorescent antibody test (IFAT)
Gioia Capelli, Alda Natale, Stefano Nardelli, Antonio Frangipane di Regalbono, Mario Pietrobelli
Preventive Veterinary Medicine.2006; 73(4): 315.     CrossRef
Factors associated with variation in Neospora caninum bulk-milk S/P ratios in initially bulk-milk negative testing Dutch dairy herds
Chris J.M. Bartels, Gerdien van Schaik, Kees van Maanen, Willem Wouda, Thomas Dijkstra
Preventive Veterinary Medicine.2007; 81(4): 265.     CrossRef
Seroprevalence and spatial distribution of Neospora caninum in a population of beef cattle
Mélanie Loobuyck, Jenny Frössling, Ann Lindberg, Camilla Björkman
Preventive Veterinary Medicine.2009; 92(1-2): 116.     CrossRef
Flock-level seroprevalence of, and risk factors for, Neospora caninum among sheep and goats in northern Jordan
Mahmoud N. Abo-Shehada, Marwan M. Abu-Halaweh
Preventive Veterinary Medicine.2010; 93(1): 25.     CrossRef
Molecular detection of Coxiella burnetii and Neospora caninum in equine aborted foetuses and neonates
Albertine Leon, Eric Richard, Christine Fortier, Claire Laugier, Guillaume Fortier, Stéphane Pronost
Preventive Veterinary Medicine.2012; 104(1-2): 179.     CrossRef
Epidemiological study of neosporosis in Uruguayan dairy herds
María V. Macchi, Alejandra Suanes, Ximena Salaberry, Federico Fernandez, José Piaggio, Andrés D. Gil
Preventive Veterinary Medicine.2020; 179: 105022.     CrossRef
Prevalence and associated risk factors of Neospora caninum infection among cattle in mainland China: A systematic review and meta-analysis
Zhu Ying, Zi-Fu Zhu, Xu Yang, Jing Liu, Qun Liu
Preventive Veterinary Medicine.2022; 201: 105593.     CrossRef
Detection of specific antibodies anti-Neospora caninum in the fallow deer (Dama dama)
Justyna Bień, Bożena Moskwa, Marek Bogdaszewski, Władyslaw Cabaj
Research in Veterinary Science.2012; 92(1): 96.     CrossRef
Serological screening for Coxiella burnetii infection and related reproductive performance in high producing dairy cows
F. López-Gatius, S. Almeria, I. Garcia-Ispierto
Research in Veterinary Science.2012; 93(1): 67.     CrossRef
Study of the risk factors associated with Neospora caninum seroprevalence in Algerian cattle populations
Farida Ghalmi, Bernard China, Asma Ghalmi, Darifa Hammitouche, Bertrand Losson
Research in Veterinary Science.2012; 93(2): 655.     CrossRef
Comparison of use of Vero cell line and suspension culture of murine macrophage to attenuation of virulence of Neospora caninum
Monireh Khordadmehr, Mehdi Namavari, Azizollah Khodakaram-Tafti, Maryam Mansourian, Abdollah Rahimian, Yahya Daneshbod
Research in Veterinary Science.2013; 95(2): 515.     CrossRef
Maternal and foetal cytokine production in dams naturally and experimentally infected with Neospora caninum on gestation day 110
L. Darwich, Y. Li, B. Serrano-Pérez, R. Mur-Novales, I. Garcia-Ispierto, O. Cabezón, F. López-Gatius, S. Almería
Research in Veterinary Science.2016; 107: 55.     CrossRef
A possible role for Neospora caninum in ovine abortion in New Zealand
D.M. West, W.E. Pomroy, M.G. Collett, F.I. Hill, A.L. Ridler, P.R. Kenyon, S.T. Morris, R.S. Pattison
Small Ruminant Research.2006; 62(1-2): 135.     CrossRef
Seroprevalence of Neospora caninum in dairy goats from Bahia, Brazil
R.S. Uzêda, A.M. Pinheiro, S.Y. Fernández, M.C.C. Ayres, L.F.P. Gondim, M.A.O. Almeida
Small Ruminant Research.2007; 70(2-3): 257.     CrossRef
Serological evidence of Neospora caninum infections in goats from La Rioja Province, Argentina
D.P. Moore, M.G. de Yaniz, A.C. Odeón, D. Cano, M.R. Leunda, E.A.J. Späth, C.M. Campero
Small Ruminant Research.2007; 73(1-3): 256.     CrossRef
The role of Neospora caninum in three cases of unexplained ewe abortions in the southern North Island of New Zealand
L. Howe, D.M. West, M.G. Collett, G. Tattersfield, R.S. Pattison, W.E. Pomroy, P.R. Kenyon, S.T. Morris, N.B. Williamson
Small Ruminant Research.2008; 75(2-3): 115.     CrossRef
Neospora caninum: A successful testing and eradication program in a dairy goat herd
Jennifer A. Altbuch, Michael J. Schofield, Catherine A. Porter, William G. Gavin
Small Ruminant Research.2012; 105(1-3): 341.     CrossRef
Flock-level risk factors associated with Neospora caninum seroprevalence in dairy goats in a semiarid region of Northeastern Brazil
C.S.A.B. Santos, S.S. Azevedo, H.S. Soares, S.S.S. Higino, F.A. Santos, M.L.C.R. Silva, H.F.J. Pena, C.J. Alves, S.M. Gennari
Small Ruminant Research.2013; 112(1-3): 239.     CrossRef
Seroprevalence and risk factors of two abortive diseases, toxoplasmosis and neosporosis, in small ruminants of the Mongo County, southern Gabon
Gael Darren Maganga, Andre Lea Abessolo, Clency Sylde Mikala Okouyi, Ingrid Labouba, Antoine Mitte Mbeang Beyeme, Jacques François Mavoungou, Ernest Agossou, Brieuc Cossic, Jean-Paul Akue
Small Ruminant Research.2016; 144: 56.     CrossRef
Serological survey of antibodies to Toxoplasma gondii and Neospora caninium in goat population in Canary Islands (Macaronesia Archipelago, Spain)
E. Rodríguez-Ponce, M. Conde, J.A. Corbera, J.R. Jaber, M.R. Ventura, C. Gutiérrez
Small Ruminant Research.2017; 147: 73.     CrossRef
Bacterial, protozoal and viral abortions in sheep and goats in South America: A review
Matías A. Dorsch, Germán J. Cantón, David Driemeier, Mark L. Anderson, Robert B. Moeller, Federico Giannitti
Small Ruminant Research.2021; 205: 106547.     CrossRef
Scenario of viral and protozoa diseases in commercial dairy goats from Zona da Mata of Minas Gerais State, Brazil
Azido Ribeiro Mataca, Renata Pimentel Bandeira de Melo, Pollyanne Raysa Fernandes Oliveira, Marcelo Fernandes Camargos, Tânia Rosária Pereira Freitas, Grazielle Cossenzo Florentino Galinari, Maria Isabel Maldonado Coelho Guedes, Marcus Rebouças, Wagnner J
Small Ruminant Research.2022; 217: 106851.     CrossRef
Establishment of an ultrasensitive and visual detection platform for Neospora caninum based-on the RPA-CRISPR/Cas12a system
Li Wang, Xin Li, Lu Li, Lili Cao, Zhiteng Zhao, Taojun Huang, Jianhua Li, Xichen Zhang, Songgao Cao, Nan Zhang, Xiaocen Wang, Pengtao Gong
Talanta.2024; 269: 125413.     CrossRef
Occasional detection of Neospora caninum DNA in frozen extended semen from naturally infected bulls
Andrea Caetano-da-Silva, Ignacio Ferre, Esther Collantes-Fernández, Vanesa Navarro, Gorka Aduriz, Carlos Ugarte-Garagalza, Luis Miguel Ortega-Mora
Theriogenology.2004; 62(7): 1329.     CrossRef
Neosporosis in dairy cattle: An update from an epidemiological perspective
John M. Gay
Theriogenology.2006; 66(3): 629.     CrossRef
Plasma pregnancy-associated glycoprotein-1 (PAG-1) concentrations during gestation in Neospora-infected dairy cows
F. López-Gatius, J.M. Garbayo, P. Santolaria, J.L. Yániz, S. Almería, A. Ayad, N.M. de Sousa, J.F. Beckers
Theriogenology.2007; 67(3): 502.     CrossRef
Intrauterine Neospora caninum inoculation of heifers and cows using contaminated semen with different numbers of tachyzoites
E. Serrano-Martínez, I. Ferre, K. Osoro, G. Aduriz, R.A. Mota, A. Martínez, I. del-Pozo, C.O. Hidalgo, L.M. Ortega-Mora
Theriogenology.2007; 67(4): 729.     CrossRef
Experimental neosporosis in bulls: Parasite detection in semen and blood and specific antibody and interferon-gamma responses
E. Serrano-Martínez, I. Ferre, A. Martínez, K. Osoro, A. Mateos-Sanz, I. del-Pozo, G. Aduriz, C. Tamargo, C.O. Hidalgo, L.M. Ortega-Mora
Theriogenology.2007; 67(6): 1175.     CrossRef
Protection against abortion linked to gamma interferon production in pregnant dairy cows naturally infected with Neospora caninum
F. López-Gatius, S. Almería, G. Donofrio, C. Nogareda, I. García-Ispierto, G. Bech-Sàbat, P. Santolaria, J.L. Yániz, M. Pabón, N.M. de Sousa, J.F. Beckers
Theriogenology.2007; 68(7): 1067.     CrossRef
Early postabortion recovery of Neospora-infected lactating dairy cows
P. Santolaria, F. López-Gatius, J. Yániz, I. García-Ispierto, C. Nogareda, G. Bech-Sàbat, B. Serrano, S. Almeria
Theriogenology.2009; 72(6): 798.     CrossRef
Neospora caninum and coxiella burnetii seropositivity are related to endocrine pattern changes during gestation in lactating dairy cows
I. García-Ispierto, C. Nogareda, J.L. Yániz, S. Almería, D. Martínez-Bello, N.M. de Sousa, J.F. Beckers, F. López-Gatius
Theriogenology.2010; 74(2): 212.     CrossRef
Immunogenicity and protective effect against murine cerebral neosporosis of recombinant NcSRS2 in different iscom formulations
Sunan Pinitkiatisakul, Mikaela Friedman, Maria Wikman, Jens G. Mattsson, Karin Lövgren-Bengtsson, Stefan Ståhl, Anna Lundén
Vaccine.2007; 25(18): 3658.     CrossRef
Transgenic Neospora caninum strains constitutively expressing the bradyzoite NcSAG4 protein proved to be safe and conferred significant levels of protection against vertical transmission when used as live vaccines in mice
V. Marugán-Hernández, L.M. Ortega-Mora, A. Aguado-Martínez, E. Jiménez-Ruíz, G. Álvarez-García
Vaccine.2011; 29(44): 7867.     CrossRef
The immune enhancement of a novel soy lecithin/β-glucans based adjuvant on native Neospora caninum tachyzoite extract vaccine in mice
Florencia Celeste Mansilla, Olga Lucía Franco-Mahecha, María Ángeles Lavoria, Dadín Prando Moore, Adrián Nicolás Giraldez, Marcela Elvira Iglesias, Maximiliano Wilda, Alejandra Victoria Capozzo
Vaccine.2012; 30(6): 1124.     CrossRef
Neospora caninum infection in dairy farms with history of abortion in West of Iran
Jamal Gharekhani, Mohammad Yakhchali
Veterinary and Animal Science.2019; 8: 100071.     CrossRef
Astroglial cells in primary culture: A valid model to study Neospora caninum infection in the CNS
A.M. Pinheiro, S.L. Costa, S.M. Freire, M.A.O. Almeida, M. Tardy, R. El Bachá, M.F.D. Costa
Veterinary Immunology and Immunopathology.2006; 113(1-2): 243.     CrossRef
Neospora caninum seroprevalence in dairy cattle in central Thailand
T Kyaw, P Virakul, M Muangyai, J Suwimonteerabutr
Veterinary Parasitology.2004; 121(3-4): 255.     CrossRef
Determination of an optimized cut-off value for the Neospora agglutination test for serodiagnosis in cattle
N Canada, C.S Meireles, J Carvalheira, A Rocha, S Sousa, J.M Correia da Costa
Veterinary Parasitology.2004; 121(3-4): 225.     CrossRef
Isolation of Neospora caninum from naturally infected white-tailed deer (Odocoileus virginianus)
M.C.B. Vianna, C. Sreekumar, K.B. Miska, D.E. Hill, J.P. Dubey
Veterinary Parasitology.2005; 129(3-4): 253.     CrossRef
Detection of antibodies to Neospora caninum in two species of wild canids, Lycalopex gymnocercus and Cerdocyon thous from Brazil
W.A. Cañón-Franco, L.E.O. Yai, S.L.P. Souza, L.C. Santos, N.A.R. Farias, J. Ruas, F.W. Rossi, A.A.B. Gomes, J.P. Dubey, S.M. Gennari
Veterinary Parasitology.2004; 123(3-4): 275.     CrossRef
Sero-epidemiological survey of Neospora caninum infection in dogs in north-eastern Italy
Gioia Capelli, Stefano Nardelli, Antonio Frangipane di Regalbono, Antonio Scala, Mario Pietrobelli
Veterinary Parasitology.2004; 123(3-4): 143.     CrossRef
Detection of Neospora caninum in an aborted goat foetus
C. Eleni, S. Crotti, E. Manuali, S. Costarelli, G. Filippini, L. Moscati, S. Magnino
Veterinary Parasitology.2004; 123(3-4): 271.     CrossRef
Shedding of Neospora caninum oocysts by dogs fed tissues from naturally infected water buffaloes (Bubalus bubalis) from Brazil
A.A.R. Rodrigues, S.M. Gennari, D.M Aguiar, C. Sreekumar, D.E. Hill, K.B. Miska, M.C.B. Vianna, J.P. Dubey
Veterinary Parasitology.2004; 124(3-4): 139.     CrossRef
Elaboration of a crude antigen ELISA for serodiagnosis of caprine neosporosis: validation of the test by detection of Neospora caninum-specific antibodies in goats from Sri Lanka
A. Naguleswaran, A. Hemphill, R.P.V.J. Rajapakse, H. Sager
Veterinary Parasitology.2004; 126(3): 257.     CrossRef
Antibodies to Neospora caninum in the blood of European bison (Bison bonasus bonasus L.) living in Poland
W. Cabaj, B. Moskwa, K. Pastusiak, J. Gill
Veterinary Parasitology.2005; 128(1-2): 163.     CrossRef
Neosporosis in South America
D.P. Moore
Veterinary Parasitology.2005; 127(2): 87.     CrossRef
Prevalence of antibodies against Neospora caninum and Toxoplasma gondii in dogs and foxes in Austria
K. Wanha, R. Edelhofer, C. Gabler-Eduardo, H. Prosl
Veterinary Parasitology.2005; 128(3-4): 189.     CrossRef
Immunisation of mice against neosporosis with recombinant NcSRS2 iscoms
Sunan Pinitkiatisakul, Jens G. Mattsson, Maria Wikman, Mikaela Friedman, Karin Lövgren Bengtsson, Stefan Ståhl, Anna Lundén
Veterinary Parasitology.2005; 129(1-2): 25.     CrossRef
Neospora caninum in pastured cattle: determination of climatic, environmental, farm management and individual animal risk factors using remote sensing and geographical information systems
L. Rinaldi, G. Fusco, V. Musella, V. Veneziano, A. Guarino, R. Taddei, G. Cringoli
Veterinary Parasitology.2005; 128(3-4): 219.     CrossRef
Serological responses to Neospora caninum in experimentally and naturally infected water buffaloes (Bubalus bubalis)
A.A.R. Rodrigues, S.M. Gennari, V.S.O. Paula, D.M. Aguiar, T.U. Fujii, W. Starke-Buzeti, R.Z. Machado, J.P. Dubey
Veterinary Parasitology.2005; 129(1-2): 21.     CrossRef
Seroprevalence of Neospora caninum in dairy and beef cattle with reproductive disorders in Japan
Masahiro Koiwai, Takahumi Hamaoka, Makoto Haritani, Shinya Shimizu, Toshiyuki Tsutsui, Mariko Eto, Itsuro Yamane
Veterinary Parasitology.2005; 130(1-2): 15.     CrossRef
Serologic immunoreactivity to Neospora caninum antigens in dogs determined by indirect immunofluorescence, western blotting and dot-ELISA
A.M. Pinheiro, M.F. Costa, B. Paule, V. Vale, M. Ribeiro, I. Nascimento, R.E. Schaer, M.A.O. Almeida, R. Meyer, S.M. Freire
Veterinary Parasitology.2005; 130(1-2): 73.     CrossRef
Seronegative conversion in four Neospora caninum-infected cows, with a low rate of transplacental transmission
T. Kyaw, J. Suwimonteerabutr, P. Virakul, C. Lohachit, W. Kalpravidh
Veterinary Parasitology.2005; 131(1-2): 145.     CrossRef
Confirmed clinical Neospora caninum infection in a boxer puppy from Argentina
W. Basso, M.C. Venturini, D. Bacigalupe, M. Kienast, J.M. Unzaga, A. Larsen, M. Machuca, L. Venturini
Veterinary Parasitology.2005; 131(3-4): 299.     CrossRef
Evaluation of three enzyme-linked immunosorbent assays for detection of antibodies to Neospora caninum in bulk milk
C.J.M. Bartels, C. van Maanen, A.M. van der Meulen, T. Dijkstra, W. Wouda
Veterinary Parasitology.2005; 131(3-4): 235.     CrossRef
Comparison of proteome and antigenic proteome between two Neospora caninum isolates
Yong-Seung Shin, Gee-Wook Shin, Young-Rim Kim, Eun-Young Lee, Hyang-Hee Yang, K.J. Palaksha, Hee-Jeong Youn, Jae-Hoon Kim, Dae-Yong Kim, A.E. Marsh, J. Lakritz, Tae-Sung Jung
Veterinary Parasitology.2005; 134(1-2): 41.     CrossRef
Seroepidemiology of Neospora caninum infection in dairy cattle herds in Mashhad area, Iran
G.R. Razmi, G.R. Mohammadi, T. Garrosi, N. Farzaneh, A.H. Fallah, M. Maleki
Veterinary Parasitology.2006; 135(2): 187.     CrossRef
Comparison of different methods for the solubilisation of Neospora caninum (Phylum Apicomplexa) antigen
Annetta Zintl, Stephen R. Pennington, Grace Mulcahy
Veterinary Parasitology.2006; 135(3-4): 205.     CrossRef
Investigation of Neospora sp. and Toxoplasma gondii antibodies in mares and in precolostral foals from Parana State, Southern Brazil
R. Locatelli-Dittrich, J.R. Dittrich, R.R.T.B. Richartz, M.E. Gasino Joineau, J. Antunes, R.D. Pinckney, I. Deconto, D.C.S. Hoffmann, V. Thomaz-Soccol
Veterinary Parasitology.2006; 135(3-4): 215.     CrossRef
Occurrence of Neospora caninum in dogs and its correlation with visceral leishmaniasis in the urban area of Campo Grande, Mato Grosso do Sul, Brazil
Renato Andreotti, Jacqueline Marques Oliveira, Elaine Araujo e Silva, Leandra Marla Oshiro, Maria de Fatima Cepa Matos
Veterinary Parasitology.2006; 135(3-4): 375.     CrossRef
Seroprevalences of antibodies to Neospora caninum and Toxoplasma gondii in zoo animals
K. Sedlák, E. Bártová
Veterinary Parasitology.2006; 136(3-4): 223.     CrossRef
Application of repeated bulk milk testing for identification of infection dynamics of Neospora caninum in Thai dairy herds
Aran Chanlun, Ulf Emanuelson, Suthida Chanlun, Suneerat Aiumlamai, Camilla Björkman
Veterinary Parasitology.2006; 136(3-4): 243.     CrossRef
Clinical Sarcocystis neurona, Sarcocystis canis, Toxoplasma gondii, and Neospora caninum infections in dogs
J.P. Dubey, Jennifer L. Chapman, Benjamin M. Rosenthal, M. Mense, Ronald L. Schueler
Veterinary Parasitology.2006; 137(1-2): 36.     CrossRef
PCR detection of Neospora caninum, Toxoplasma gondii and Encephalitozoon cuniculi in brains of wild carnivores
L Hůrková, D. Modrý
Veterinary Parasitology.2006; 137(1-2): 150.     CrossRef
Identification of a protein disulfide isomerase of Neospora caninum in excretory–secretory products and its IgA binding and enzymatic activities
Min Liao, Liqing Ma, Hiroshi Bannai, Eung-goo Lee, Zhixun Xie, Xiaofei Tang, Houshuang Zhang, Xuenan Xuan, Kozo Fujisaki
Veterinary Parasitology.2006; 139(1-3): 47.     CrossRef
Neospora caninum antibodies in commercial fetal bovine serum
Maria P. Torres, Ynes R. Ortega
Veterinary Parasitology.2006; 140(3-4): 352.     CrossRef
Seroprevalence of Neospora caninum in non-carnivorous wildlife from Spain
S. Almería, D. Vidal, D. Ferrer, M. Pabón, M.I.G. Fernández-de-Mera, F. Ruiz-Fons, V. Alzaga, I. Marco, C. Calvete, S. Lavin, C. Gortazar, F. López-Gatius, J.P. Dubey
Veterinary Parasitology.2007; 143(1): 21.     CrossRef
Neospora caninum detected in feral rodents
M.C. Jenkins, C. Parker, D. Hill, R.D. Pinckney, R. Dyer, J.P. Dubey
Veterinary Parasitology.2007; 143(2): 161.     CrossRef
Evaluation of serological tests for the diagnosis of Neospora caninum infection in dogs: Optimization of cut off titers and inhibition studies of cross-reactivity with Toxoplasma gondii
Deise A.O. Silva, Janaína Lobato, Tiago W.P. Mineo, José R. Mineo
Veterinary Parasitology.2007; 143(3-4): 234.     CrossRef
Serodiagnosis of Neospora caninum infection in cattle using a recombinant tNcSRS2 protein-based ELISA
Jing Liu, Jinshu Yu, Ming Wang, Qun Liu, Wei Zhang, Chong Deng, Jun Ding
Veterinary Parasitology.2007; 143(3-4): 358.     CrossRef
Prevalence of antibodies against Toxoplasma gondii and Neospora caninum in Hungarian red foxes (Vulpes vulpes)
Eva-Britt Jakubek, Robert Farkas, Vilmos Pálfi, Jens G. Mattsson
Veterinary Parasitology.2007; 144(1-2): 39.     CrossRef
Presence of Neospora caninum specific antibodies in three dairy farms in Georgia and two in Texas
Ynes R. Ortega, Maria P. Torres, Kristina D. Mena
Veterinary Parasitology.2007; 144(3-4): 353.     CrossRef
Risk factors for canine neosporosis in farm and kennel dogs in southern Italy
Paola Paradies, Gioia Capelli, Gabriella Testini, Cinzia Cantacessi, Alexander J. Trees, Domenico Otranto
Veterinary Parasitology.2007; 145(3-4): 240.     CrossRef
Isolation and molecular detection of Neospora caninum from naturally infected sheep from Brazil
H.F.J. Pena, R.M. Soares, A.M.A. Ragozo, R.M. Monteiro, L.E.O. Yai, S.M. Nishi, S.M. Gennari
Veterinary Parasitology.2007; 147(1-2): 61.     CrossRef
Dynamics of anti-Neospora caninum antibodies during gestation in chronically infected dairy cows
C. Nogareda, F. López-Gatius, P. Santolaria, I. García-Ispierto, G. Bech-Sàbat, M. Pabón, M. Mezo, M. Gonzalez-Warleta, J.A. Castro-Hermida, J. Yániz, S. Almeria
Veterinary Parasitology.2007; 148(3-4): 193.     CrossRef
Prevalence of anti-Toxoplasma gondii and anti-Neospora caninum antibodies in goats slaughtered in the public slaughterhouse of Patos city, Paraíba State, Northeast region of Brazil
Eduardo B. Faria, Solange M. Gennari, Hilda F.J. Pena, Ana Célia R. Athayde, Maria Luana C.R. Silva, Sérgio S. Azevedo
Veterinary Parasitology.2007; 149(1-2): 126.     CrossRef
First identification of Neospora caninum infection in aborted bovine foetuses in China
W. Zhang, C. Deng, Q. Liu, J. Liu, M. Wang, K.G. Tian, X.L. Yu, D.M. Hu
Veterinary Parasitology.2007; 149(1-2): 72.     CrossRef
Isolation of Neospora caninum from dairy zero grazing cattle in Israel
L. Fish, M. Mazuz, T. Molad, I. Savitsky, V. Shkap
Veterinary Parasitology.2007; 149(3-4): 167.     CrossRef
Neosporosis in Beagle dogs: Clinical signs, diagnosis, treatment, isolation and genetic characterization of Neospora caninum
J.P. Dubey, M.C.B. Vianna, O.C.H. Kwok, D.E. Hill, K.B. Miska, W. Tuo, G.V. Velmurugan, M. Conors, M.C. Jenkins
Veterinary Parasitology.2007; 149(3-4): 158.     CrossRef
Histopathological and immunohistochemical aspects of Neospora caninum diagnosis in bovine aborted fetuses
C.A. Pescador, L.G. Corbellini, E.C. Oliveira, D.L. Raymundo, D. Driemeier
Veterinary Parasitology.2007; 150(1-2): 159.     CrossRef
Evaluation of Neospora caninum and Toxoplasma gondii infections in alpaca (Vicugna pacos) and llama (Lama glama) aborted foetuses from Peru
E. Serrano-Martínez, E. Collantes-Fernández, A. Chávez-Velásquez, A. Rodríguez-Bertos, E. Casas-Astos, V. Risco-Castillo, R. Rosadio-Alcantara, L.M. Ortega-Mora
Veterinary Parasitology.2007; 150(1-2): 39.     CrossRef
Seroepidemiology of Neospora caninum and Toxoplasma gondii infection in yaks (Bos grunniens) in Qinghai, China
J. Liu, J.Z. Cai, W. Zhang, Q. Liu, D. Chen, J.P. Han, Q.R. Liu
Veterinary Parasitology.2008; 152(3-4): 330.     CrossRef
Seroprevalence of Neospora caninum in dogs in south-western Poland
Katarzyna Płoneczka, Michał Mazurkiewicz
Veterinary Parasitology.2008; 153(1-2): 168.     CrossRef
Seroepidemiological study of Neospora caninum infection in dogs found in dairy farms and urban areas of Aguascalientes, Mexico
C. Cruz-Vázquez, L. Medina-Esparza, A. Marentes, E. Morales-Salinas, Z. Garcia-Vázquez
Veterinary Parasitology.2008; 157(1-2): 139.     CrossRef
Neospora caninum, potential cause of abortions in dairy cows: The current serological follow-up in Slovakia
K. Reiterová, S. Špilovská, D. Antolová, P. Dubinský
Veterinary Parasitology.2009; 159(1): 1.     CrossRef
Neospora caninum associated with epidemic abortions in dairy cattle: The first clinical neosporosis report in Turkey
Oğuz Kul, Nalan Kabakci, Kader Yildiz, Naci Öcal, Hakan Kalender, N. Aycan İlkme
Veterinary Parasitology.2009; 159(1): 69.     CrossRef
Effects of crossbreed pregnancies on the abortion risk of Neospora caninum-infected dairy cows
S. Almería, F. López-Gatius, I. García-Ispierto, C. Nogareda, G. Bech-Sàbat, B. Serrano, P. Santolaria, J.L. Yániz
Veterinary Parasitology.2009; 163(4): 323.     CrossRef
Seroprevalence of Neospora caninum in dairy cattle ranches with high abortion rate: Special emphasis to serologic co-existence with Toxoplasma gondii, Brucella abortus and Listeria monocytogenes
Kader Yildiz, Oguz Kul, Cahit Babur, Selcuk Kılıc, Aycan N. Gazyagcı, Bekir Celebi, I. Safa Gurcan
Veterinary Parasitology.2009; 164(2-4): 306.     CrossRef
The first report of ovine cerebral neosporosis and evaluation of Neospora caninum prevalence in sheep in New South Wales
Stephanie Bishop, Jessica King, Peter Windsor, Michael P. Reichel, John Ellis, Jan Šlapeta
Veterinary Parasitology.2010; 170(1-2): 137.     CrossRef
The prevalence and spatial clustering of Neospora caninum in dairy herds in Norway
S. Klevar, M. Norström, J. Tharaldsen, T. Clausen, C. Björkman
Veterinary Parasitology.2010; 170(1-2): 153.     CrossRef
Neospora caninum and Toxoplasma gondii antibodies in European brown hares in the Czech Republic, Slovakia and Austria
Eva Bártová, Kamil Sedlák, František Treml, Ivan Holko, Ivan Literák
Veterinary Parasitology.2010; 171(1-2): 155.     CrossRef
Abortions in bovines and Neospora caninum transmission in an embryo transfer center
Vanessa Silvestre Ferreira de Oliveira, Gema Álvarez-Garcia, Luis Miguel Ortega-Mora, Lígia Miranda Ferreira Borges, Andréa Caetano da Silva
Veterinary Parasitology.2010; 173(3-4): 206.     CrossRef
In vitro isolation and identification of the first Neospora caninum isolate from European bison (Bison bonasus bonasus L.)
Justyna Bień, Bożena Moskwa, Władysław Cabaj
Veterinary Parasitology.2010; 173(3-4): 200.     CrossRef
Evaluation of Toxoplasma gondii and Neospora caninum infections in sheep from Uberlândia, Minas Gerais State, Brazil, by different serological methods
G.F. Rossi, D.D. Cabral, D.P. Ribeiro, A.C.A.M. Pajuaba, R.R. Corrêa, R.Q. Moreira, T.W.P. Mineo, J.R. Mineo, D.A.O. Silva
Veterinary Parasitology.2011; 175(3-4): 252.     CrossRef
Serological profile of Toxoplasma gondii and Neospora caninum infection in commercial sheep from São Paulo State, Brazil
Helio Langoni, Haroldo Greca, Felipe F. Guimarães, Leila S. Ullmann, Fernanda C. Gaio, Robson S. Uehara, Eric P. Rosa, Rogério M. Amorim, Rodrigo C. Da Silva
Veterinary Parasitology.2011; 177(1-2): 50.     CrossRef
Toxoplasma gondii and Neospora caninum in wildlife: Common parasites in Belgian foxes and Cervidae?
S. De Craeye, N. Speybroeck, D. Ajzenberg, M.L. Dardé, F. Collinet, P. Tavernier, S. Van Gucht, P. Dorny, K. Dierick
Veterinary Parasitology.2011; 178(1-2): 64.     CrossRef
Seroprevalence of Toxoplasma gondii and Neospora caninum infections in goats in Poland
Michał Czopowicz, Jarosław Kaba, Olga Szaluś-Jordanow, Mariusz Nowicki, Lucjan Witkowski, Tadeusz Frymus
Veterinary Parasitology.2011; 178(3-4): 339.     CrossRef
Seroprevalence and risk factors associated with neosporosis in sheep and dogs from farms
Gustavo Puglia Machado, Mariana Kikuti, Helio Langoni, Antonio Carlos Paes
Veterinary Parasitology.2011; 182(2-4): 356.     CrossRef
Neosporosis in animals—The last five years
J.P. Dubey, G. Schares
Veterinary Parasitology.2011; 180(1-2): 90.     CrossRef
Factors associated with infection by Neospora caninum in dogs in Brazil
Patrícia Mara Lopes Sicupira, Vanessa Carvalho Sampaio de Magalhães, Gideão da Silva Galvão, Maria Julia Salim Pereira, Luís Fernando Pita Gondim, Alexandre Dias Munhoz
Veterinary Parasitology.2012; 185(2-4): 305.     CrossRef
Potential involvement of Neospora caninum in naturally occurring ovine abortions in New Zealand
L. Howe, M.G. Collett, R.S. Pattison, J. Marshall, D.M. West, W.E. Pomroy
Veterinary Parasitology.2012; 185(2-4): 64.     CrossRef
Seroprevalence of Toxoplasma gondii and Neospora caninum in dairy goats from Romania
Anamaria Iovu, Adriana Györke, Viorica Mircean, Raluca Gavrea, Vasile Cozma
Veterinary Parasitology.2012; 186(3-4): 470.     CrossRef
Occurrence of Neospora caninum and Toxoplasma gondii infections in ovine and caprine abortions
B. Moreno, E. Collantes-Fernández, A. Villa, A. Navarro, J. Regidor-Cerrillo, L.M. Ortega-Mora
Veterinary Parasitology.2012; 187(1-2): 312.     CrossRef
Characterization of Neospora caninum microneme protein 10 (NcMIC10) and its potential use as a diagnostic marker for neosporosis
Jigang Yin, Guanggang Qu, Lili Cao, Qichang Li, Raymond Fetterer, Xiaosheng Feng, Quan Liu, Guiping Wang, Dongmei Qi, Xichen Zhang, Eliseo Miramontes, Mark Jenkins, Naisheng Zhang, Wenbin Tuo
Veterinary Parasitology.2012; 187(1-2): 28.     CrossRef
The importance of vertical transmission of Neospora sp. in naturally infected horses
Ana Maria Antonello, Felipe Lamberti Pivoto, Giovana Camillo, Patricia Braunig, Luis Antonio Sangioni, Endrigo Pompermayer, Fernanda Silveira Flores Vogel
Veterinary Parasitology.2012; 187(3-4): 367.     CrossRef
Increased incidence of DNA amplification in follicular than in uterine and blood samples indicates possible tropism of Neospora caninum to the ovarian follicle
Andressa F. Silva, Lucia Rangel, Carlos Garcia Ortiz, Elizabeth Morales, Eraldo L. Zanella, Uziel Castillo-Velázquez, Carlos G. Gutierrez
Veterinary Parasitology.2012; 188(1-2): 175.     CrossRef
Seroprevalence and risk factors for Neospora caninum in sheep in the state Minas Gerais, southeastern Brazil
Gislaine da Silva Andrade, Fábio Raphael Pascoti Bruhn, Christiane Maria Barcellos Magalhãe Rocha, Alessandro de Sá Guimarães, Aurora Maria Guimarães Gouveia, Antônio Marcos Guimarães
Veterinary Parasitology.2012; 188(1-2): 168.     CrossRef
Immunohistochemical and polymerase chain reaction studies in Neospora caninum experimentally infected broiler chicken embryonated eggs
Azizollah Khodakaram-Tafti, Maryam Mansourian, Mehdi Namavari, Arsalan Hosseini
Veterinary Parasitology.2012; 188(1-2): 10.     CrossRef
Development of latex agglutination test with recombinant NcSAG1 for the rapid detection of antibodies to Neospora caninum in cattle
Marjan Moraveji, Arsalan Hosseini, Nasrin Moghaddar, Mohammad Mehdi Namavari, Mohammad Hadi Eskandari
Veterinary Parasitology.2012; 189(2-4): 211.     CrossRef
Neospora caninum in Estonian dairy herds in relation to herd size, reproduction parameters, bovine virus diarrhoea virus, and bovine herpes virus 1
Brian Lassen, Toomas Orro, Annely Aleksejev, Kerli Raaperi, Toivo Järvis, Arvo Viltrop
Veterinary Parasitology.2012; 190(1-2): 43.     CrossRef
Dose-dependent immunogenicity of a soluble Neospora caninum tachyzoite-extract vaccine formulated with a soy lecithin/β-glucan adjuvant in cattle
F.C. Mansilla, W. Czepluch, D.A. Malacari, Y.P. Hecker, D. Bucafusco, O.L. Franco-Mahecha, D.P. Moore, A.V. Capozzo
Veterinary Parasitology.2013; 197(1-2): 13.     CrossRef
First molecular detection of Neospora caninum in European brown bear (Ursus arctos)
A. Čobádiová, B. Víchová, V. Majláthová, K. Reiterová
Veterinary Parasitology.2013; 197(1-2): 346.     CrossRef
Detection of Neospora caninum DNA in semen of experimental infected rams with no evidence of horizontal transmission in ewes
S.S. Syed-Hussain, L. Howe, W.E. Pomroy, D.M. West, S.L. Smith, N.B. Williamson
Veterinary Parasitology.2013; 197(3-4): 534.     CrossRef
Seroprevalence and risk factors of Neospora spp. in donkeys from Southern Italy
T. Machačová, E. Bártová, A. Di Loria, K. Sedlák, J. Guccione, D. Fulgione, V. Veneziano
Veterinary Parasitology.2013; 198(1-2): 201.     CrossRef
Neospora caninum DNA detection by TaqMan real-time PCR assay in experimentally infected pregnant heifers
Gabriel Ribas Pereira, Fernanda Silveira Flores Vogel, Rodrigo Camponogara Bohrer, Janduí Escarião da Nóbrega, Gustavo Freitas Ilha, Paulo Roberto Antunes da Rosa, Werner Giehl Glanzner, Giovana Camillo, Patricia Braunig, João Francisco Coelho de Oliveira
Veterinary Parasitology.2014; 199(3-4): 129.     CrossRef
Adaptation of a commercial ELISA to determine the IgG avidity in sheep experimentally and naturally infected with Neospora caninum
S.S. Syed-Hussain, L. Howe, W.E. Pomroy, D.M. West, S.L. Smith, N.B. Williamson
Veterinary Parasitology.2014; 203(1-2): 21.     CrossRef
Transmission paths of Neospora caninum in a dairy herd of crossbred cattle in the northeast of Brazil
Vanessa Carvalho Sampaio de Magalhães, Uillians Volkart de Oliveira, Sonia Carmen Lopo Costa, Ivanildo dos Anjos Santos, Maria Julia Salim Pereira, Alexandre Dias Munhoz
Veterinary Parasitology.2014; 202(3-4): 257.     CrossRef
Detection of Neospora caninum-DNA in feces collected from dogs in Shenyang (China) and ITS1 phylogenetic analysis
Jianhua Li, Pengfei He, Yanhui Yu, Ling Du, Pengtao Gong, Guocai Zhang, Xichen Zhang
Veterinary Parasitology.2014; 205(1-2): 361.     CrossRef
Fluorescent ester dye-based assays for the in vitro measurement of Neospora caninum proliferation
Caroline M. Mota, Marcela D. Ferreira, Lourenço F. Costa, Patrício S.C. Barros, Murilo V. Silva, Fernanda M. Santiago, José R. Mineo, Tiago W.P. Mineo
Veterinary Parasitology.2014; 205(1-2): 14.     CrossRef
Gallus gallus domesticus are resistant to infection with Neospora caninum tachyzoites of the NC-1 strain
Alexandre Dias Munhoz, Tatiane Fernanda do Amaral, Luiz Ricardo Gonçalves, Vera Maria Barbosa de Moraes, Rosangela Zacarias Machado
Veterinary Parasitology.2014; 206(3-4): 123.     CrossRef
Vertical transmission in experimentally infected sheep despite previous inoculation with Neospora caninum NcNZ1 isolate
S.S. Syed-Hussain, L. Howe, W.E. Pomroy, D.M. West, M. Hardcastle, N.B. Williamson
Veterinary Parasitology.2015; 208(3-4): 150.     CrossRef
Neospora caninum in crows from Israel
H. Salant, M.L. Mazuz, I. Savitsky, A. Nasereddin, E. Blinder, G. Baneth
Veterinary Parasitology.2015; 212(3-4): 375.     CrossRef
Detection of Neospora caninum-DNA in brain tissues from pigeons in Changchun, Jilin (China)
Ling Du, Dongsheng Yang, Tao Zhai, Pengtao Gong, Xichen Zhang, Jianhua Li
Veterinary Parasitology.2015; 214(1-2): 171.     CrossRef
Anti-Neospora caninum and anti-Sarcocystis spp. specific antibodies cross-react with Besnoitia besnoiti and influence the serological diagnosis of bovine besnoitiosis
P. García-Lunar, G. Moré, L. Campero, L.M. Ortega-Mora, G. Álvarez-García
Veterinary Parasitology.2015; 214(1-2): 49.     CrossRef
Immunization with inactivated antigens of Neospora caninum induces toll-like receptors 3, 7, 8 and 9 in maternal-fetal interface of infected pregnant heifers
M.S. Marin, Y.P. Hecker, S. Quintana, S.E. Pérez, M.R. Leunda, G.J. Cantón, E.R. Cobo, D.P. Moore, A.C. Odeón
Veterinary Parasitology.2017; 243: 12.     CrossRef
Bovine macrophage-derived extracellular traps act as early effectors against the abortive parasite Neospora caninum
Zhengkai Wei, Yanan Wang, Xu Zhang, Xiaocen Wang, Pengtao Gong, Jianhua Li, Anja Taubert, Carlos Hermosilla, Xichen Zhang, Zhengtao Yang
Veterinary Parasitology.2018; 258: 1.     CrossRef
Annotating the ‘hypothetical’ in hypothetical proteins: In-silico analysis of uncharacterised proteins for the Apicomplexan parasite, Neospora caninum
Larissa Calarco, John Ellis
Veterinary Parasitology.2019; 265: 29.     CrossRef
Neospora GRA6 possesses immune-stimulating activity and confers efficient protection against Neospora caninum infection in mice
Ragab M. Fereig, Naomi Shimoda, Hanan H. Abdelbaky, Yasuhiro Kuroda, Yoshifumi Nishikawa
Veterinary Parasitology.2019; 267: 61.     CrossRef
The evaluation of attenuated Neospora caninum by long-term passages on murine macrophage cell line in prevention of vertical transmission in mice
Laleh Amini, Mehdi Namavari, Azizollah Khodakaram-Tafti, Mohammad Reza Divar, Seyed Mohammad Hossein Hosseini
Veterinary Parasitology.2020; 283: 109171.     CrossRef
Global seroprevalence of Neospora spp. in horses and donkeys: A systematic review and meta-analysis
Erfan Javanmardi, Hamidreza Majidiani, Seyyed Ali Shariatzadeh, Davood Anvari, Sadegh Shamsinia, Ezatollah Ghasemi, Bahareh Kordi, Morteza Shams, Ali Asghari
Veterinary Parasitology.2020; 288: 109299.     CrossRef
Global prevalence of Toxoplasma gondii infection in the aborted fetuses and ruminants that had an abortion: A systematic review and meta-analysis
Tooran Nayeri, Shahabeddin Sarvi, Mahmood Moosazadeh, Ahmad Daryani
Veterinary Parasitology.2021; 290: 109370.     CrossRef
Transcriptome profiling of Madin-Darby bovine kidney cells uncover differences in the susceptibility of cattle to Toxoplasma gondii and Neospora caninum
Xiaojin Li, Kai He, Weifeng Qian, Chen Li, Suhui Hu, Min Zhang, Tianqi Wang, Wenchao Yan, Meng Qi
Veterinary Parasitology.2023; 324: 110072.     CrossRef
Seroprevalence of anti-Toxoplasma gondii and anti-Neospora caninum antibodies in domestic mammals from two distinct regions in the semi-arid region of Northeastern Brazil
Ana Isabel Arraes-Santos, Andreina C. Araújo, Maíra F. Guimarães, Josenilton R. Santos, Hilda F.J. Pena, Solange M. Gennari, Sérgio S. Azevedo, Marcelo B. Labruna, Maurício C. Horta
Veterinary Parasitology: Regional Studies and Reports.2016; 5: 14.     CrossRef
Toxoplasmosis in cats in northeastern Brazil: Frequency, associated factors and coinfection with Neospora caninum , feline immunodeficiency virus and feline leukemia virus
Alexandre Dias Munhoz, Samir Batista Hage, Rebeca Dalety Santos Cruz, Ana Paula Fernandes Calazans, Fabiana Lessa Silva, George Rêgo Albuquerque, Luciana Carvalho Lacerda
Veterinary Parasitology: Regional Studies and Reports.2017; 8: 35.     CrossRef
Seroprevalence of anti-Neospora caninum antibodies in sheep from the rapidly expanding flock of Rio de Janeiro, Brazil
R.I.J. Cosendey, F.C.R. de Oliveira, E. Frazão-Teixeira, G.N. de Souza, F.Z. Brandão, A.M.R. Ferreira, W. Lilenbaum
Veterinary Parasitology: Regional Studies and Reports.2018; 14: 59.     CrossRef
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M. Lefkaditis, R. Mpairamoglou, A. Sossidou, K. Spanoudis, M. Tsakiroglou
Veterinary Parasitology: Regional Studies and Reports.2020; 19: 100365.     CrossRef
Serological survey of Neospora spp. and Besnoitia spp. in horses in Portugal
Helga Waap, Uillians Volkart de Oliveira, Telmo Nunes, Jacinto Gomes, Tiago Gomes, Andrea Bärwald, Alexandre Dias Munhoz, Gereon Schares
Veterinary Parasitology: Regional Studies and Reports.2020; 20: 100391.     CrossRef
Equine Protozoal Myeloencephalitis associated with Neospora caninum in a USA captive bred zebra (Equus zebra)
Stephani Ruppert, Jung Keun Lee, Antoinette E. Marsh
Veterinary Parasitology: Regional Studies and Reports.2021; 26: 100620.     CrossRef
Herd and animal level prevalences and risk factors for Neospora caninum infection in cattle in the state of Paraíba, northeastern Brazil
Amanda Rafaela Alves Maia, Renata Pimentel Bandeira de Melo, Rinaldo Aparecido Mota, Inácio José Clementino, Clebert José Alves, Carolina de Sousa Américo Batista Santos, Leise Gomes Fernandes, Sérgio Santos de Azevedo
Veterinary Parasitology: Regional Studies and Reports.2023; 40: 100866.     CrossRef
The seroprevalence and risk factors for exposure to Neospora caninum and Neospora hughesi in Ontario broodmares
Olivia Johns, David L. Pearl, Robert A. Foster, John Barta, Tracey Chenier
Veterinary Parasitology: Regional Studies and Reports.2024; 50: 101002.     CrossRef
Frequency of Besnoitia besnoiti and Neospora caninum antibodies in cattle and small ruminants from greater Cairo and Beni Suef governorates, Egypt
Ragab M. Fereig, Dina B. Salama, Fatma K. Salem, Sherin R. Rouby, Raafat M. Shaapan, Sara Draz, Bassma S.M. Elsawy, Magdy M. Elgioushy, Sarah A. Altwaim, Shawky M. Aboelhadid, Caroline F. Frey
Veterinary Parasitology: Regional Studies and Reports.2024; 53: 101078.     CrossRef
A longitudinal study on the effects of maternal and offspring seropositivity for Neospora caninum on birth weight, survival, reproductive performance and abortion in the offspring
Amir Abbas Mohieddini, Mohammad Mahdi Delavari, Reza Hemmati Baghbanani, Vahid Akbarinejad
Veterinary Parasitology: Regional Studies and Reports.2025; 58: 101206.     CrossRef
Prevalence of antibodies to Neospora caninum in dogs from Amazon, Brazil
W.A. Cañón-Franco, D.P. Bergamaschi, M.B. Labruna, L.M.A. Camargo, S.L.P. Souza, J.C.R. Silva, A. Pinter, J.P. Dubey, S.M. Gennari
Veterinary Parasitology.2003; 115(1): 71.     CrossRef
Dermatitis in a dog associated with an unidentified Toxoplasma gondii-like parasite
J.P. Dubey, A.L. Pimenta, L.C.S. Abboud, R.R. Ravasani, M. Mense
Veterinary Parasitology.2003; 116(1): 51.     CrossRef
Toxoplasma gondii, Neospora caninum, Sarcocystis neurona, and Sarcocystis canis-like infections in marine mammals
J.P Dubey, R Zarnke, N.J Thomas, S.K Wong, W.Van Bonn, M Briggs, J.W Davis, R Ewing, M Mense, O.C.H Kwok, S Romand, P Thulliez
Veterinary Parasitology.2003; 116(4): 275.     CrossRef
Study on outbreak of Neospora caninum-associated abortion in dairy cows in Tabriz (Northwest Iran) by serological, molecular and histopathologic methods
A. Nematollahi, G.H. Moghaddam, R. Jaafari, J. Ashrafi Helan, M. Norouzi
Asian Pacific Journal of Tropical Medicine.2013; 6(12): 942.     CrossRef
Serological study of Neospora caninum in dogs and wildlife in a nature conservation area in southern Portugal
H. WAAP, T. NUNES, Y. VAZ, A. LEITÃO
Parasitology Open.2017;[Epub]     CrossRef
Toltrazuril treatment to control diaplacentalNeospora caninumtransmission in experimentally infected pregnant mice
B. GOTTSTEIN, G. R. RAZMI, P. AMMANN, H. SAGER, N. MÜLLER
Parasitology.2005; 130(1): 41.     CrossRef
Cellular and immunological basis of the host-parasite relationship during infection withNeospora caninum
A. HEMPHILL, N. VONLAUFEN, A. NAGULESWARAN
Parasitology.2006; 133(3): 261.     CrossRef
The host-parasite relationship in pregnant cattle infected withNeospora caninum
ELISABETH A. INNES
Parasitology.2007; 134(13): 1903.     CrossRef
NcGRA2as a molecular target to assess the parasiticidal activity of toltrazuril againstNeospora caninum
M. STROHBUSCH, N. MÜLLER, A. HEMPHILL, G. GREIF, B. GOTTSTEIN
Parasitology.2008; 135(9): 1065.     CrossRef
Detection ofNeospora caninumin aborted bovine fetuses and dam blood samples by nested PCR and ELISA and seroprevalence in Beijing and Tianjin, China
L. YAO, N. YANG, Q. LIU, M. WANG, W. ZHANG, W. F. QIAN, Y. F. HU, J. DING
Parasitology.2009; 136(11): 1251.     CrossRef
Identification of a gene cluster for cell-surface genes of the SRS superfamily inNeospora caninumand characterization of the novelSRS9gene
V. RISCO-CASTILLO, V. MARUGÁN-HERNÁNDEZ, A. FERNÁNDEZ-GARCÍA, A. AGUADO-MARTÍNEZ, E. JIMÉNEZ-RUIZ, S. RODRÍGUEZ-MARCO, G. ÁLVAREZ-GARCÍA, L. M. ORTEGA-MORA
Parasitology.2011; 138(14): 1832.     CrossRef
Seroprevalence of Toxoplasma gondii and Neospora caninum infection in dairy cows in subtropical southern China
M. J. XU, Q. Y. LIU, J. H. FU, A. J. NISBET, D. S. SHI, X. H. HE, Y. PAN, D. H. ZHOU, H. Q. SONG, X. Q. ZHU
Parasitology.2012; 139(11): 1425.     CrossRef
Clinical outcome and vertical transmission variability among canine Neospora caninum isolates in a pregnant mouse model of infection
ANDREA DELLARUPE, JAVIER REGIDOR-CERRILLO, ELENA JIMÉNEZ-RUIZ, GEREON SCHARES, JUAN MANUEL UNZAGA, MARÍA CECILIA VENTURINI, LUIS M. ORTEGA-MORA
Parasitology.2014; 141(3): 356.     CrossRef
Approaches for the vaccination and treatment ofNeospora caninuminfections in mice and ruminant models
ANDREW HEMPHILL, ADRIANA AGUADO-MARTÍNEZ, JOACHIM MÜLLER
Parasitology.2016; 143(3): 245.     CrossRef
Characteristic pro-inflammatory cytokines and host defence cathelicidin peptide produced by human monocyte-derived macrophages infected withNeospora caninum
E. Boucher, M. Marin, R. Holani, M. Young-Speirs, D.M. Moore, E.R. Cobo
Parasitology.2018; 145(7): 871.     CrossRef
Detection of Neospora caninum DNA in cases of bovine and ovine abortion in the South-West of Scotland
P. M. Bartley, S. Guido, C. Mason, H. Stevenson, F. Chianini, H. Carty, E. A. Innes, F. Katzer
Parasitology.2019; 146(07): 979.     CrossRef
Risk factors associated with seroprevalence of Neospora caninum in dogs from urban and rural areas of milk and coffee production in Minas Gerais state, Brazil
C. I. NOGUEIRA, L. P. MESQUITA, C. C. ABREU, K. Y. R. NAKAGAKI, J. N. SEIXAS, P. S. BEZERRA, C. M. B. M. ROCHA, A. M. GUIMARAES, A. P. PECONICK, M. S. VARASCHIN
Epidemiology and Infection.2013; 141(11): 2286.     CrossRef
Plasmacytoid and conventional dendritic cells are early producers of IL‐12 inNeospora caninum‐infected mice
Luzia Teixeira, Ana Sofia Botelho, Sandro Dá Mesquita, Alexandra Correia, Filipe Cerca, Renata Costa, Paula Sampaio, António Gil Castro, Manuel Vilanova
Immunology & Cell Biology.2010; 88(1): 79.     CrossRef
A recent update about seroprevalence of ovine neosporosis in Northern Egypt and its associated risk factors
Abdelfattah Selim, Hanem Khater, Hamdan I. Almohammed
Scientific Reports.2021;[Epub]     CrossRef
Neospora caninum infection in dairy cattle in Egypt: a serosurvey and associated risk factors
Abdelfattah Selim, Ayed Alshammari, Hattan S. Gattan, Mohamed Marzok, Mohamed Salem, Omar A. AL-Jabr
Scientific Reports.2023;[Epub]     CrossRef
Seroprevalence and risk factors for Neospora spp. infection in equine in Egypt
Ayed Alshammari, Hattan S. Gattan, Mohamed Marzok, Abdelfattah Selim
Scientific Reports.2023;[Epub]     CrossRef
Transcriptome and Histopathological Changes in Mouse Brain Infected with Neospora caninum
Maki Nishimura, Sachi Tanaka, Fumiaki Ihara, Yoshikage Muroi, Junya Yamagishi, Hidefumi Furuoka, Yutaka Suzuki, Yoshifumi Nishikawa
Scientific Reports.2015;[Epub]     CrossRef
Changes in neurotransmitter levels and expression of immediate early genes in brain of mice infected with Neospora caninum
Fumiaki Ihara, Maki Nishimura, Yoshikage Muroi, Hidefumi Furuoka, Naoaki Yokoyama, Yoshifumi Nishikawa
Scientific Reports.2016;[Epub]     CrossRef
Nucleotide-binding oligomerization domain-containing protein 2 prompts potent inflammatory stimuli during Neospora caninum infection
Marcela Davoli-Ferreira, Denise M. Fonseca, Caroline M. Mota, Murilo S. Dias, Djalma S. Lima-Junior, Murilo V. da Silva, Gustavo F. S. Quirino, Dario S. Zamboni, João S. Silva, Tiago W. P. Mineo
Scientific Reports.2016;[Epub]     CrossRef
The state of art of neutrophil extracellular traps in protozoan and helminthic infections
César Díaz-Godínez, Julio C. Carrero
Bioscience Reports.2019;[Epub]     CrossRef
Serological study ofNeospora caninuminfection in dogs in central China
Shuai Wang, Zhijun Yao, Nian Zhang, Dong Wang, Jingbo Ma, Shiguo Liu, Bin Zheng, Bin Zhang, Kuo Liu, Haizhu Zhang
Parasite.2016; 23: 25.     CrossRef
Prevalence of Neospora spp. in donkeys in China
Wei Cong, Lan-Bi Nie, Si-Yuan Qin, Wei-Li Wang, Ai-Dong Qian, Qing-Feng Meng
Parasite.2018; 25: 16.     CrossRef
Infectious Neuromuscular Diseases of Dogs and Cats
Mark T. Troxel
Topics in Companion Animal Medicine.2009; 24(4): 209.     CrossRef
First cases of animal diseases published since 2000 6. First update of dog diseases
Th.A.M. Elsinghorst
Veterinary Quarterly.2004; 26(1): 12.     CrossRef
A mixture model for the detection ofNeosporosiswithout a gold standard
Andrés Farall, Ricardo Maronna, Tomás Tetzlaff
Journal of Applied Statistics.2011; 38(5): 913.     CrossRef
Prevalence and Risk Factors of Brucellosis, Toxoplasmosis, and Neosporosis Among Yanbian Yellow Cattle in Jilin Province, China
Fei Liu, Dan Wang, Si-Cong Yang, Jun-Hui Zhu, Jian-Ming Li, Kun Shi, Rui Du, Quan Zhao
Vector-Borne and Zoonotic Diseases.2019; 19(3): 217.     CrossRef
Genome Wide Identification of Mutational Hotspots in the Apicomplexan Parasite Neospora caninum and the Implications for Virulence
Larissa Calarco, Joel Barratt, John Ellis, Geoff McFadden
Genome Biology and Evolution.2018; 10(9): 2417.     CrossRef
Who let the cats out? A global meta-analysis on risk of parasitic infection in indoor versus outdoor domestic cats (Felis catus)
Kayleigh Chalkowski, Alan E. Wilson, Christopher A. Lepczyk, Sarah Zohdy
Biology Letters.2019; 15(4): 20180840.     CrossRef
Reevaluation of the Toxoplasma gondii and Neospora caninum genomes reveals misassembly, karyotype differences, and chromosomal rearrangements
Luisa Berná, Pablo Marquez, Andrés Cabrera, Gonzalo Greif, María E. Francia, Carlos Robello
Genome Research.2021; 31(5): 823.     CrossRef
Characterization of the B‐cell immune response elicited in BALB/c mice challenged with Neospora caninum tachyzoites
Luzia Teixeira, Andreia Marques, Carla Sofia Meireles, Ana Rita Seabra, Diana Rodrigues, Pedro Madureira, Augusto M. R. Faustino, Carolina Silva, Adília Ribeiro, Paula Ferreira, José Manuel Correia da Costa, Nuno Canada, Manuel Vilanova
Immunology.2005; 116(1): 38.     CrossRef
Analysis of the immune response to Neospora caninum in a model of intragastric infection in mice
L. TEIXEIRA, A. S. BOTELHO, A. R. BATISTA, C. S. MEIRELES, A. RIBEIRO, H. S. DOMINGUES, J. M. CORREIA DA COSTA, A. G. CASTRO, A. M. R. FAUSTINO, M. VILANOVA
Parasite Immunology.2007; 29(1): 23.     CrossRef
The development of immune responses in Balb/c mice following inoculation with attenuated or virulentNeospora caninumtachyzoites
P. M. BARTLEY, S. E. WRIGHT, S. W. MALEY, D. BUXTON, M. NATH, E. A. INNES
Parasite Immunology.2009; 31(7): 392.     CrossRef
Meningoencephalomyelitis Caused byNeospora caninumin a Juvenile Fallow Deer (Dama dama)
S. Soldati, M. Kiupel, A. Wise, R. Maes, C. Botteron, N. Robert
Journal of Veterinary Medicine Series A.2004; 51(6): 280.     CrossRef
Some Factors Affecting the Abortion Rate in Dairy Herds with High Incidence ofNeospora-Associated Abortions are Different in Cows and Heifers
JL Yániz, F López-Gatius, I García-Ispierto, G Bech-Sàbat, B Serrano, C Nogareda, JA Sanchez-Nadal, S Almeria, P Santolaria
Reproduction in Domestic Animals.2009;[Epub]     CrossRef
Vaccination with γ‐IrradiatedNeospora caninumTachyzoites Protects Mice Against Acute Challenge withN. caninum
S. RAMAMOORTHY, D. S. LINDSAY, G. G. SCHURIG, S. M. BOYLE, R. B. DUNCAN, R. VEMULAPALLI, N. SRIRANGANATHAN
Journal of Eukaryotic Microbiology.2006; 53(2): 151.     CrossRef
Neosporosis in a young dog presenting with dermatitis and neuromuscular signs
S. P. Boyd, P. A. Barr, H. W. Brooks, J. P. Orr
Journal of Small Animal Practice.2005; 46(2): 85.     CrossRef
Neosporosis and hammondiosis in dogs
M. P. Reichel, J. T. Ellis, J. P. Dubey
Journal of Small Animal Practice.2007; 48(6): 308.     CrossRef
Seroprevalence of Antibodies toNeospora caninumin Urban and Rural Dogs in north‐west Italy
E. Ferroglio, M. Pasino, F. Ronco, A. Benà, A. Trisciuoglio
Zoonoses and Public Health.2007; 54(3-4): 135.     CrossRef
Anti‐neosporal IgG and IgE antibodies in Canine Neosporosis
E. E. V. Jesus, M. A. O. Almeida, A. M. Atta
Zoonoses and Public Health.2007; 54(9-10): 387.     CrossRef
CASE REPORT: Detection of Neospora caninum tachyzoites in cerebrospinal fluid of a dog following prednisone and cyclosporine therapy
Bradley I. Galgut, Kyathanahalli S. Janardhan, Tanya M. Grondin, Kenneth R. Harkin, Mary T. Wight-Carter
Veterinary Clinical Pathology.2010; 39(3): 386.     CrossRef
What is your diagnosis? Fine‐needle aspirate of ulcerative skin lesions in a dog
Aradhana Gupta, Shannon Stroup, Andrea Dedeaux, Rudy W. Bauer, Stephen D. Gaunt
Veterinary Clinical Pathology.2011; 40(3): 401.     CrossRef
Detection ofNeospora caninumTachyzoites in Canine Cerebrospinal Fluid
Lluís Gaitero, Sònia Añor, Patrícia Montoliu, Ángeles Zamora, Martí Pumarol
Journal of Veterinary Internal Medicine.2006; 20(2): 410.     CrossRef
Protozoal Hepatitis Associated with Immunosuppressive Therapy in a Dog
D.R. Fry, K.D. McSporran, J.T. Ellis, C. Harvey
Journal of Veterinary Internal Medicine.2009; 23(2): 366.     CrossRef
Retracted: Prevalence of Toxoplasma gondii and Neospora caninum in different types of raw milk and traditional dairy product samples
Mahtab Alipour, Ebrahim Rahimi, Amir Shakerian
Journal of Food Safety.2018;[Epub]     CrossRef
Stem cell‐derived enteroid cultures as a tool for dissecting host‐parasite interactions in the small intestinal epithelium
Miriam F. Hares, Ellen‐Alana Tiffney, Luke J. Johnston, Lisa Luu, Christopher J. Stewart, Robin J. Flynn, Janine L. Coombes
Parasite Immunology.2021;[Epub]     CrossRef
Plasma Concentrations of Pregnancy‐Associated Glycoproteins Measured Using Anti‐Bovine PAG‐2 Antibodies on Day 120 of Gestation Predict Abortion in Dairy Cows Naturally Infected withNeospora caninum
I García‐Ispierto, S Almería, B Serrano, NM de Sousa, JF Beckers, F López‐Gatius
Reproduction in Domestic Animals.2013; 48(4): 613.     CrossRef
First detection and molecular identification of Neospora caninum from naturally infected cattle and sheep in North Africa
Y. Amdouni, M. R. Rjeibi, S. Awadi, M. Rekik, M. Gharbi
Transboundary and Emerging Diseases.2018; 65(4): 976.     CrossRef
Seroprevalence of canine neosporosis and bovine viral diarrhoea in dairy cattle in selected regions of Kenya
Moses O. Olum, Erick O. Mungube, James Njanja, John Kidali, Edward Njenga, Monicah Maichomo, Victor T. Tsuma, John Mugambi
Transboundary and Emerging Diseases.2020; 67(S2): 154.     CrossRef
Active shedding ofNeospora caninumdetected in Australian wild canids in a nonexperimental context
Mikaeylah J. Davidson, Jose L. Huaman, Carlo Pacioni, Danielle Stephens, Yvette Hitchen, Teresa G. Carvalho
Transboundary and Emerging Diseases.2022; 69(4): 1862.     CrossRef
Development of Rapid Immunochromatographic Test with Recombinant NcSAG1 for Detection of Antibodies toNeospora caninumin Cattle
Min Liao, Shoufa Zhang, Xuenan Xuan, Guohong Zhang, Xiaohong Huang, Ikuo Igarashi, Kozo Fujisaki
Clinical and Vaccine Immunology.2005; 12(7): 885.     CrossRef
Epidemiology and Control of Neosporosis andNeospora caninum
J. P. Dubey, G. Schares, L. M. Ortega-Mora
Clinical Microbiology Reviews.2007; 20(2): 323.     CrossRef
Dense-Granule Protein NcGRA7, a New Marker for the Serodiagnosis ofNeospora caninumInfection in Aborting Cows
Penglong Huang, Min Liao, Houshuang Zhang, Eung-goo Lee, Yoshifumi Nishikawa, Xuenan Xuan
Clinical and Vaccine Immunology.2007; 14(12): 1640.     CrossRef
Indoleamine 2,3-Dioxygenase Is Involved in Defense againstNeospora caninumin Human and Bovine Cells
Katrin Spekker, Markus Czesla, Vanessa Ince, Kathrin Heseler, Silvia K. Schmidt, Gereon Schares, Walter Däubener
Infection and Immunity.2009; 77(10): 4496.     CrossRef
Identification of Vaccine Candidate Peptides in the NcSRS2 Surface Protein ofNeospora caninumby Using CD4+Cytotoxic T Lymphocytes and Gamma Interferon-Secreting T Lymphocytes of Infected Holstein Cattle
Lauren M. Staska, Christopher J. Davies, Wendy C. Brown, Travis C. McGuire, Carlos E. Suarez, Joo Youn Park, Bruce A. Mathison, Jeffrey R. Abbott, Timothy V. Baszler
Infection and Immunity.2005; 73(3): 1321.     CrossRef
Characterization and functional analysis of Toxoplasma Golgi-associated proteins identified by proximity labeling
Rebecca R. Pasquarelli, Justin J. Quan, Emily S. Cheng, Vivian Yang, Timmie A. Britton, Jihui Sha, James A. Wohlschlegel, Peter J. Bradley, Louis M. Weiss
mBio.2024;[Epub]     CrossRef
Multivalent Interactions Drive the Toxoplasma AC9:AC10:ERK7 Complex To Concentrate ERK7 in the Apical Cap
Peter S. Back, William J. O’Shaughnessy, Andy S. Moon, Pravin S. Dewangan, Michael L. Reese, Peter J. Bradley, Jon P. Boyle
mBio.2022;[Epub]     CrossRef
IMC29 Plays an Important Role in Toxoplasma Endodyogeny and Reveals New Components of the Daughter-Enriched IMC Proteome
Peter S. Back, Andy S. Moon, Rebecca R. Pasquarelli, Hannah N. Bell, Juan A. Torres, Allan L. Chen, Jihui Sha, Ajay A. Vashisht, James A. Wohlschlegel, Peter J. Bradley, Jon P. Boyle
mBio.2023;[Epub]     CrossRef
Canine central nervous system neosporosis: clinical, laboratory and diagnostic imaging findings in six dogs
Alessandro Didiano, Paola Monti, Olivier Taeymans, Giunio Bruto Cherubini
Veterinary Record Case Reports.2020;[Epub]     CrossRef
Population Structure of Toxoplasma gondii: Clonal Expansion Driven by Infrequent Recombination and Selective Sweeps
L. David Sibley, James W. Ajioka
Annual Review of Microbiology.2008; 62(1): 329.     CrossRef
A Review of Some Protozoan Parasites Causing Infertility in Farm Animals
B. Y. Kaltungo, I. W. Musa
ISRN Tropical Medicine.2013; 2013: 1.     CrossRef
Neospora caninum Infection in Cattle in the Province of Kohgiluyeh and Boyer Ahmad, Southwest of Iran: Seroprevalence and Molecular Assessment
Atefeh Darijani, Nasir Arefkhah, Sepehr Shahriarirad, Sina Zoghi, Mehdi Namavari, Abdolali Moshfe, Marzieh Zaraei, Bahador Sarkari, Francisco Gonzalez Salazar
Journal of Parasitology Research.2021; 2021: 1.     CrossRef
Modelling and Analyzing the Potential Controls for Neospora caninum Infection in Dairy Cattle Using an Epidemic Approach
Yue Liu, Ioannis Magouras, Wing-Cheong Lo, Toshikazu Kuniya
Complexity.2021;[Epub]     CrossRef
Determination of B and T Cell Epitopes in Neospora caninum Immune Mapped Protein‐1 (IMP‐1): Implications in Vaccine Design against Neosporosis
Naser Nazari, Bahareh Kordi, Bahman Maleki, Morteza Shams, Esfandiar Azizi, Hamidreza Majidiani, Razi Naserifar, Adam Reich
BioMed Research International.2022;[Epub]     CrossRef
Towards the First Multiepitope Vaccine Candidate against Neospora caninum in Mouse Model: Immunoinformatic Standpoint
Morteza Shams, Bahman Maleki, Bahareh Kordi, Hamidreza Majidiani, Naser Nazari, Hamid Irannejad, Ali Asghari, Abdelwahab Omri
BioMed Research International.2022;[Epub]     CrossRef
Neospora caninum SRS2 Protein: Essential Vaccination Targets and Biochemical Features for Next‐Generation Vaccine Design
Ali Asghari, Bahareh Kordi, Bahman Maleki, Hamidreza Majidiani, Morteza Shams, Razi Naserifar, Jane Hanrahan
BioMed Research International.2022;[Epub]     CrossRef
Evaluation of a SRS2 Sandwich Commercial Enzyme-Linked Immunosorbent Assay for the Detection of Anti-Neospora Caninum Antibodies in Bovine and Canine Sera
Farida Ghalmi, Bernard China, Rachid Kaidi, Bertrand Losson
Journal of Veterinary Diagnostic Investigation.2009; 21(1): 108.     CrossRef
Comparison of different serological methods to detect antibodies specific to Neospora caninum in bovine and canine sera
Farida Ghalmi, Bernard China, Mark Jenkins, Naouelle Azzag, Bertand Losson
Journal of Veterinary Diagnostic Investigation.2014; 26(1): 136.     CrossRef
In Silico Investigation of Conserved miRNAs and Their Targets From the Expressed Sequence Tags in Neospora Caninum Genome
Moumita Das, Mahmudul Hasan, Sharmin Akter, Sawrab Roy, Binayok Sharma, Md. Shahidur Rahman Chowdhury, Md. Irtija Ahsan, Rubaiat Nazneen Akhand, Md Bashir Uddin, Syed Sayeem Uddin Ahmed
Bioinformatics and Biology Insights.2021;[Epub]     CrossRef
Histological and immunohistochemical characterization of the inflammatory and glial cells in the central nervous system of goat fetuses and adult male goats naturally infected with Neospora caninum
Rafael Carneiro Costa, Débora Ribeiro Orlando, Camila Costa Abreu, Karen Yumi Ribeiro Nakagaki, Leonardo Pereira Mesquita, Lismara Castro Nascimento, Aline Costa Silva, Paulo César Maiorka, Ana Paula Peconick, Djeison Lutier Raymundo, Mary Suzan Varaschin
BMC Veterinary Research.2014;[Epub]     CrossRef
Prevalence of Bovine Viral Diarrhoea Virus (BVDV), Bovine Herpes Virus 1 (BHV 1), Leptospirosis and Neosporosis, and associated risk factors in 161 Irish beef herds
Damien Barrett, Mervyn Parr, John Fagan, Alan Johnson, Jamie Tratalos, Francis Lively, Michael Diskin, David Kenny
BMC Veterinary Research.2018;[Epub]     CrossRef
The serostatus of Brucella spp., Chlamydia abortus, Coxiella burnetii and Neospora caninum in cattle in three cantons in Bosnia and Herzegovina
Adis Softic, Kassahun Asmare, Erik Georg Granquist, Jacques Godfroid, Nihad Fejzic, Eystein Skjerve
BMC Veterinary Research.2018;[Epub]     CrossRef
Evidence of Australian wild deer exposure to N. caninum infection and potential implications for the maintenance of N. caninum sylvatic cycle
Jose L. Huaman, Carlo Pacioni, Mark Doyle, David M. Forsyth, Karla J. Helbig, Teresa G. Carvalho
BMC Veterinary Research.2023;[Epub]     CrossRef
Serological survey of antibodies against Toxoplasma gondii and Neospora caninum in pigs from various regions of Poland
Agata Augustyniak, Arkadiusz Dors, Rafał Niemyjski, Małgorzata Pomorska-Mól
BMC Veterinary Research.2025;[Epub]     CrossRef
Diagnostic studies of abortion in Danish cattle 2015–2017
Godelind Alma Wolf-Jäckel, Mette Sif Hansen, Gitte Larsen, Elisabeth Holm, Jørgen Steen Agerholm, Tim Kåre Jensen
Acta Veterinaria Scandinavica.2020;[Epub]     CrossRef
Role of the chemokine receptor CCR5-dependent host defense system in Neospora caninum infections
Chisa Abe, Sachi Tanaka, Maki Nishimura, Fumiaki Ihara, Xuenan Xuan, Yoshifumi Nishikawa
Parasites & Vectors.2015;[Epub]     CrossRef
Development of a loop-mediated isothermal amplification technique and comparison with quantitative real-time PCR for the rapid visual detection of canine neosporosis
Aongart Mahittikorn, Nipa Thammasonthijarern, Amonrattana Roobthaisong, Ruenruetai Udonsom, Supaluk Popruk, Sukhontha Siri, Hirotake Mori, Yaowalark Sukthana
Parasites & Vectors.2017;[Epub]     CrossRef
A novel loop-mediated isothermal amplification-based test for detecting Neospora caninum DNA
Andrea Estefanía Ramos, Marina Muñoz, Jesús Alfredo Cortés-Vecino, Paola Barato, Manuel Alfonso Patarroyo
Parasites & Vectors.2017;[Epub]     CrossRef
Seroprevalence of Neospora caninum-specific antibodies in German breeding bitches
Rodolfo Villagra-Blanco, Lora Angelova, Theresa Conze, Gereon Schares, Andrea Bärwald, Anja Taubert, Carlos Hermosilla, Axel Wehrend
Parasites & Vectors.2018;[Epub]     CrossRef
Species-specific differences in Toxoplasma gondii, Neospora caninum and Besnoitia besnoiti seroprevalence in Namibian wildlife
Anne Seltmann, Gereon Schares, Ortwin H. K. Aschenborn, Sonja K. Heinrich, Susanne Thalwitzer, Bettina Wachter, Gábor Á. Czirják
Parasites & Vectors.2020;[Epub]     CrossRef
Temporal transcriptomic changes in microRNAs involved in the host immune response and metabolism during Neospora caninum infection
Jin-Ming Chen, Shan-Shan Zhao, De-Liang Tao, Jing-Yu Li, Xin Yang, Ying-Ying Fan, Jun-Ke Song, Qun Liu, Guang-Hui Zhao
Parasites & Vectors.2023;[Epub]     CrossRef
Construction of luciferase-expressing Neospora caninum and drug screening
Fei Wang, Yangfei Xue, Yanqun Pei, Meng Yin, Zhepeng Sun, Zihui Zhou, Jing Liu, Qun Liu
Parasites & Vectors.2024;[Epub]     CrossRef
Roles of CD122+ Cells in Resistance against Neospora caninum Infection in a Murine Model
Yoshifumi NISHIKAWA, Houshuang ZHANG, Hany M. IBRAHIM, Kyoko YAMADA, Hideyuki NAGASAWA, Xuenan XUAN
Journal of Veterinary Medical Science.2010; 72(10): 1275.     CrossRef
Detection of Nesopora caninum-Specific DNA from Cerebrospinal Fluid by Polymerase Chain Reaction in a Dog with Confirmed Neosporosis
Kyohei ISHIGAKI, Masahiko NOYA, Yumiko KAGAWA, Kazunori IKE, Hiromitsu ORIMA, Soichi IMAI
Journal of Veterinary Medical Science.2012; 74(8): 1051.     CrossRef
Seroprevalences of Toxoplasma gondii and Neospora caninum in Pet Rabbits in Japan
Doaa SALMAN, Eiji OOHASHI, Adel Elsayed Ahmed MOHAMED, Abd El-Raheem ABD EL-MOTTELIB, Tadashi OKADA, Makoto IGARASHI
Journal of Veterinary Medical Science.2014; 76(6): 855.     CrossRef
Enzyme-linked immunosorbent assays using recombinant TgSAG2 and NcSAG1 to detect Toxoplasma gondii and Neospora caninum-specific antibodies in domestic animals in Turkey
Mo ZHOU, Shinuo CAO, Ferda SEVINC, Mutlu SEVINC, Onur CEYLAN, Mingming LIU, Guanbo WANG, Paul Franck Adjou MOUMOUNI, Charoonluk JIRAPATTHARASATE, Hiroshi SUZUKI, Yoshifumi NISHIKAWA, Xuenan XUAN
Journal of Veterinary Medical Science.2016; 78(12): 1877.     CrossRef
A clinical case of neosporosis in a 4-week-old holstein friesian calf which developed hindlimb paresis postnatally
Karin UESAKA, Kenji KOYAMA, Noriyuki HORIUCHI, Yoshiyasu KOBAYASHI, Yoshifumi NISHIKAWA, Hisashi INOKUMA
Journal of Veterinary Medical Science.2018; 80(2): 280.     CrossRef
Seroepidemiology of Toxoplasma gondii and Neospora caninum in Seals around Hokkaido, Japan
Kei FUJII, Chiharu KAKUMOTO, Mari KOBAYASHI, Sachiko SAITO, Tatsuya KARIYA, Yukiko WATANABE, Xuenan XUAN, Ikuo IGARASHI, Masatsugu SUZUKI
Journal of Veterinary Medical Science.2007; 69(4): 393.     CrossRef
Serological Survey of Neospora caninum Infection among Dogs in Japan through Species-Specific ELISA
Naoki KUBOTA, Yoshimi SAKATA, Naomi MIYAZAKI, Kazuhito ITAMOTO, Hiroshi BANNAI, Yoshifumi NISHIKAWA, Xuenan XUAN, Hisashi INOKUMA
Journal of Veterinary Medical Science.2008; 70(8): 869.     CrossRef
Detection of Neospora caninum from Farm-Bred Young Blue Foxes (Alopex lagopus) in China
XiuLing YU, NanHua CHEN, DongMei HU, Wei ZHANG, XiaoXia LI, BaoYue WANG, LiPing KANG, XiangDong LI, Qun LIU, KeGong TIAN
Journal of Veterinary Medical Science.2009; 71(1): 113.     CrossRef
Prevalence of Toxoplasma and Neospora Antibodies in Clinically Healthy Household Dogs in Some Parts of the Kinki and Shikoku Regions
Takehisa SOMA, Shigeki IMAMOTO, Takashi HASE, Akira KATO, Kazuhiro SUNAGAWA, Masakazu OHARA, Xuenan XUAN
Journal of the Japan Veterinary Medical Association.2015; 68(9): 581.     CrossRef
Canine encephalitis — inflammation of the brain
Ellen Andrews
The Veterinary Nurse.2019; 10(5): 257.     CrossRef
A photoactivatable crosslinking system reveals protein interactions in the Toxoplasma gondii inner membrane complex
Charles Paul Choi, Andy Seong Moon, Peter Sungmin Back, Yasaman Jami‐Alahmadi, Ajay Amar Vashisht, James Akira Wohlschlegel, Peter John Bradley, Isabelle Coppens
PLOS Biology.2019; 17(10): e3000475.     CrossRef
Alveolin proteins in the Toxoplasma inner membrane complex form a highly interconnected structure that maintains parasite shape and replication
Peter S. Back, Vignesh Senthilkumar, Charles P. Choi, Justin J. Quan, Qing Lou, Anne K. Snyder, Andrew M. Ly, Justin G. Lau, Z. Hong Zhou, Gary E. Ward, Peter J. Bradley, Kami Kim
PLOS Biology.2024; 22(9): e3002809.     CrossRef
Identification of Novel Proteins in Neospora caninum Using an Organelle Purification and Monoclonal Antibody Approach
Catherine S. Sohn, Tim T. Cheng, Michael L. Drummond, Eric D. Peng, Sarah J. Vermont, Dong Xia, Stephen J. Cheng, Jonathan M. Wastling, Peter J. Bradley, Gordon Langsley
PLoS ONE.2011; 6(4): e18383.     CrossRef
Neospora caninum infection in aborting bovines and lost fetuses: A systematic review and meta-analysis
Tooran Nayeri, Mahmood Moosazadeh, Shahabeddin Sarvi, Ahmad Daryani, Benjamin M. Rosenthal
PLOS ONE.2022; 17(5): e0268903.     CrossRef
Identification of IMC43, a novel IMC protein that collaborates with IMC32 to form an essential daughter bud assembly complex in Toxoplasma gondii
Rebecca R. Pasquarelli, Peter S. Back, Jihui Sha, James A. Wohlschlegel, Peter J. Bradley, Christopher J. Tonkin
PLOS Pathogens.2023; 19(10): e1011707.     CrossRef
BCC0 collaborates with IMC32 and IMC43 to form the Toxoplasma gondii essential daughter bud assembly complex
Rebecca R. Pasquarelli, Jihui Sha, James A. Wohlschlegel, Peter J. Bradley, Sébastien Besteiro
PLOS Pathogens.2024; 20(7): e1012411.     CrossRef
Development of competitive ELISA for neosporosis by employing immunoproteomics
Yong-seung Shin, Eung-goo Lee, Gee-wook Shin, Young-rim Kim, Eun-young Lee, Jae-hoon Kim, Hwan Jang, Dae-yong Kim, Yong-hwan Kim, Gon-sup Kim, Myung-deuk Suh, Tae-sung Jung
Clinical Proteomics.2004;[Epub]     CrossRef
Seroprevalence of Neospora caninum in local Bali dog
I Made Dwinata, Ida Bagus Made Oka, Kadek Karang Agustina, I Made Damriyasa
Veterinary World.2018; 11(7): 926.     CrossRef
Seroepidemiological study of Neospora caninum in equids using c-ELISA in Erbil Province, Iraq
Khalid Jabar Aziz, Farhad Buzo Mikaeel, Sarhang Hasan Azeez, Samir Jawdat Bilal
Folia Parasitologica.2024;[Epub]     CrossRef
Wild boar (Sus scrofa) – reservoir host of Toxoplasma gondii, Neospora caninum and Anaplasma phagocytophilum in Slovakia
Katarína Reiterová, Silvia Špilovská, Lucia Blaňarová, Markéta Derdáková, Andrea Čobádiová, Vladimír Hisira
Acta Parasitologica.2016;[Epub]     CrossRef
Prevalence of Toxoplasma gondii and Neospora caninum in red foxes in Slovakia
Katarína Reiterová, Silvia Špilovská, Andrea Čobádiová, Zuzana Hurníková
Acta Parasitologica.2016;[Epub]     CrossRef
Infection agents of Didelphidae (Didelphimorphia) of Brazil: an underestimated matter in zoonoses research
Matheus M. Bitencourt, Alexandra M. R. Bezerra
Mammalia.2022; 86(2): 105.     CrossRef
Neospora caninum immune mapped protein 1 (NcIMP1) is a novel vaccine candidate against neosporosis
Xia CUI, Daoyu YANG, Tao LEI, Hui WANG, Pan HAO, Qun LIU
Frontiers of Agricultural Science and Engineering.2015; 2(1): 66.     CrossRef
Investigation of Toxoplasma gondii and Neospora caninum as cause of ovine abortion in affected flocks of Urmia, northwest of Iran
A. Khodadadi, F. Malekifard, R. A. Batavani
BULGARIAN JOURNAL OF VETERINARY MEDICINE.2022; 25(2): 308.     CrossRef
Microcephaly and hydrocephalus in a sheep fetus infected with Neospora caninum in Southern Brazil – Short communication
Jéssica Aline Withoeft, Leonardo Silva Da Costa, Lucas Marian, Letícia Ferreira Baumbach, Juliana Do Canto Olegário, Luiz Cláudio Miletti, Cláudio Wageck Canal, Renata Assis Casagrande
Acta Veterinaria Hungarica.2022; 70(3): 226.     CrossRef
Neospora caninum and Toxoplasma gondii serodiagnosis in human immunodeficiency virus carriers
Leandra Marla Oshiro, Ana Rita Coimbra Motta-Castro, Solange Zacalusni Freitas, Rodrigo Casquero Cunha, Rosangela Locatelli Dittrich, Andréa Christine Ferreira Meirelles, Renato Andreotti
Revista da Sociedade Brasileira de Medicina Tropical.2015; 48(5): 568.     CrossRef
Seroprevalence of Neospora caninum and Toxoplasma gondii in dogs from an urban area of North-eastern Brazil: a spatial approach
Islanne Barbosa de Souza, Pollyanne Raysa Fernandes, Tatiene Rossana Móta Silva, Cleber Vinicius Brito Santos, Naiara Mirelly Marinho da Silva, Carlos Roberto Cruz Ubirajara Filho, Gílcia Aparecida de Carvalho, Leucio Câmara Alves, Rinaldo Aparecido Mota,
Revista da Sociedade Brasileira de Medicina Tropical.2019;[Epub]     CrossRef
Molecular detection of protozoa of the Sarcocystidae family in sheep from the State of Rio Grande do Sul, Brazil
Luiza Pires Portella, Gustavo Cauduro Cadore, Luis Antonio Sangioni, Marta Elena Machado Alves, Raiza Chemeris, Larissa Picada Brum, Fernanda Silveira Flores Vogel
Ciência Rural.2016; 46(9): 1613.     CrossRef
PCR-based identification of Neospora caninum in the umbilical cord of a newborn calf in Brazil
Nilton Azevedo da Cunha Filho, Plínio Aguiar de Oliveira, Fernando Caetano de Oliveira, Felipe Geraldo Pappen, Cintia Lidiane Guidotti Aguiar, Alceu Gonçalves dos Santos Junior, André Luis Costa-da-Silva, Fabio Pereira Leivas Leite, Nara Amélia da Rosa Fa
Ciência Rural.2017;[Epub]     CrossRef
Toxoplasma gondii induced abortions in a goat herd in Rio de Janeiro, Brazil
Gabriela Oliveira Pereira, Asheley Henrique Barbosa Pereira, Marilene de Farias Brito, Caroline Argenta Pescador, Daniel Guimarães Ubiali
Ciência Rural.2021;[Epub]     CrossRef
Anti-Toxoplasma gondii and anti-Neospora caninum antibodies in dogs with and without neurological signs
Silvana Marques Caramalac, Simone Marques Caramalac, Bets-Saba Naate Naumann Cerqueira Leite, Pablo Menegon Castilho, Ana Flávia Minutti, Thais Agostinho Martins, João Luis Garcia, Luiz Daniel de Barros, Felipe Gazza Romão, Mariana Isa Poci Palumbo
Ciência Rural.2023;[Epub]     CrossRef
Aborto infeccioso por Neospora spp. em equino ˗ relato de caso
J.I. Octaviano, F.P. Carneiro, M.A. Redoan, M.A. Alonso, C.B. Fernandes
Arquivo Brasileiro de Medicina Veterinária e Zootecnia.2020; 72(4): 1381.     CrossRef
Spatial distribution and evaluation of risk factors for bovine neosporosis in Rondônia, Brazil
A.M. Andrade Júnior, W.D.Z. Lopes, G. Felippelli, B.C. Cruz, W.G. Maciel, V.E. Soares, L.L. Ferreira, J.L. Garcia, B.S.L. Nino, A. Minutti, G.A.M. Rossi, V.S. Jayme, D.B. Martins, E. Arnhold, W.F.P. Teixeira
Arquivo Brasileiro de Medicina Veterinária e Zootecnia.2023; 75(2): 205.     CrossRef
Intra-uterine exposure of horses to Sarcocystis spp. antigens
A.M. Antonello, G.C. Cadore, F.L. Pivoto, G. Camillo, P. Braunig, L.A. Sangioni, E. Pompermayer, L.F.P. Gondim, F.S.F. Vogel
Arquivo Brasileiro de Medicina Veterinária e Zootecnia.2016; 68(2): 271.     CrossRef
Coinfecções por Leishmania infantum, Neospora caninum e Toxoplasma gondii em cães necropsiados da região central do Rio Grande do Sul, Brasil
F.R. Ratzlaff, A.M. Engelmann, F.S. Luz, P. Bräunig, C.M. Andrade, R.A. Fighera, S.A. Botton, F.S. F. Vogel, L. Pötter, L.A. Sangioni
Arquivo Brasileiro de Medicina Veterinária e Zootecnia.2018; 70(1): 109.     CrossRef
Detecção molecular de Neospora caninum em macaco-da-noite (Aotus azarae) de vida livre no estado do Mato Grosso: relato de caso
T.L.C. Costa, G.A. Iglesias, J.M.A. Rosa, H.J. Bento, L.A.S. Rondelli, F. Furlan, T.O. Morgado, V. Dutra, S.H.R. Corrêa
Arquivo Brasileiro de Medicina Veterinária e Zootecnia.2018; 70(4): 1227.     CrossRef
Placental lesions associated with abortion and stillbirth in goats naturally infected by Neospora caninum
Leonardo P. Mesquita, Rafael C. Costa, Clayton I. Nogueira, Camila C. Abreu, Débora R. Orlando, Ivan Ascari Junior, Ana Paula Peconick, Mary S. Varaschin
Pesquisa Veterinária Brasileira.2018; 38(3): 444.     CrossRef
Serological response to Neospora caninum infection in goats and agreement between three diagnostic techniques to detect caprine neosporosis
Pomy C.P. Kim, Renata P.B. Melo, Jonatas C. Almeida, José G. Silva, Muller Ribeiro-Andrade, Wagnner J.N. Porto, José W. Pinheiro Junior, Rinaldo A. Mota
Pesquisa Veterinária Brasileira.2019; 39(1): 25.     CrossRef
Performance of the Dot-blot test method for detecting antibodies to Sarcocystis spp. in cattle
Maiara S.T. Ferreira, Fagner D. Fernandes, Marta E.M. Alves, Patricia Bräunig, Luis A. Sangioni, Fernanda S.F. Vogel
Pesquisa Veterinária Brasileira.2020; 40(5): 385.     CrossRef
ESTUDO MORFOLÓGICO DE EMBRIÕES BOVINOS FERTILIZADOS IN VITRO EXPOSTOS EXPERIMENTALMENTE À NEOSPORA CANINUM
M. D’ Angelo, A.G. Galuppo, N.M.C. Zerio, G.M. Melo, E.M. Pituco, L.H. Okuda
Arquivos do Instituto Biológico.2006; 73(2): 211.     CrossRef
SEROPREVALENCE AND RISK FACTORS ASSOCIATED TO NEOSPORA CANINUM IN FEMALE BOVINES FROM THE WESTERN SÃO PAULO STATE, BRAZIL
D.M. Aguiar, D.P Lacerda, R.C. Orlandelli, A.O. Medina, S.S Azevedo, L.H. Okuda, V. Castro, M.E. Genovez, E.M. Pituco
Arquivos do Instituto Biológico.2011; 78(2): 183.     CrossRef
CONSTRUÇÃO DE UM INDICADOR QUANTITATIVO (STATUS DE SAÚDE) PARA AVALIAÇÃO DA QUALIDADE DE SAÚDE ANIMAL DE PROPRIEDADES RURAIS
C.R. Padovani, A.V.M Stachissini, H.F. da Costa, F.F. Aragon, J.R. Modolo
Arquivos do Instituto Biológico.2011; 78(3): 359.     CrossRef
Gestational monitoring in buffalo females: detection of Neospora caninum by PCR
Raúl Miguel Reyes-Sandoval, Dora Romero-Salas, Jenny Jovanna Chaparro-Gutiérrez, Anabel Cruz-Romero, Karla María López-Hernández, Miguel Ángel Lammoglia-Villagómez, Milagros González-Hernández, Marco Antonio Alarcón-Zapata, Rebeca Isabel Vergara-Reyes
Animal Reproduction.2023;[Epub]     CrossRef
Detection and molecular analysis of Toxoplasma gondii and Neospora caninum from dogs with neurological disorders
Helio Langoni, Guilherme Matteucci, Bruno Medici, Lucilene Granuzio Camossi, Virgínia Bodelão Richini-Pereira, Rodrigo Costa da Silva
Revista da Sociedade Brasileira de Medicina Tropical.2012; 45(3): 365.     CrossRef
Aborto ovino associado com infecção por Sarcocystis sp
Caroline A. Pescador, Luís G. Corbellini, Eduardo C. de Oliveira, Paulo M. Bandarra, Juliano S. Leal, Pedro M.O. Pedroso, David Driemeier
Pesquisa Veterinária Brasileira.2007; 27(10): 393.     CrossRef
Freqüência de anticorpos anti-Neospora caninum em soros de caprinos do estado de São Paulo e sua relação com o manejo dos animais
José R. Modolo, Anee V.M. Stachissini, Solange M. Gennari, Jitender P. Dubey, Helio Langoni, Carlos R. Padovani, Lígia V. Barrozo, Bárbara L.S. Leite
Pesquisa Veterinária Brasileira.2008; 28(12): 597.     CrossRef
Neospora caninum seropositivity in cattle breeds in the South Fluminense Paraíba Valley, state of Rio de Janeiro
Alexandre D. Munhoz, Maria Júlia S. Pereira, Walter Flausino, Carlos Wilson G. Lopes
Pesquisa Veterinária Brasileira.2009; 29(1): 29.     CrossRef
Anticorpos IgG anti-Neospora caninum e Toxoplasma gondii em búfalas (Bubalus bubalis) criadas no estado do Pará
Sandro P. Silva, Rinaldo A. Mota, Eduardo B. Faria, Erika F.T.S. Fernandes, Orestes L.S. Neto, Pedro P.F. Albuquerque, Hilma L.T. Dias
Pesquisa Veterinária Brasileira.2010; 30(5): 443.     CrossRef
IgM e IgG como marcadores da infecção transplacentária por Neospora caninum em fetos bovinos
Gustavo C. Cadore, Fernanda S.F. Vogel, Luis Antonio Sangioni, Hilda F.J. Pena, Solange M. Gennari
Pesquisa Veterinária Brasileira.2010; 30(7): 551.     CrossRef
Prevalência de anticorpos anti-Neospora caninum (Apicomplexa: Sarcocystidae) em bovinos leiteiros de propriedades rurais em três microrregiões no estado do Maranhão
Whaubtyfran C. Teixeira, Rosângela S. Uzêda, Luís F.P. Gondim, Maria I.S. Silva, Helder M. Pereira, Leucio C. Alves, Maria A.G. Faustino
Pesquisa Veterinária Brasileira.2010; 30(9): 729.     CrossRef
Fatores associados a soroprevalência de Neospora caninum e Toxoplasma gondii em rebanhos caprinos na região sul de Minas Gerais
Mary S. Varaschin, Antônio M. Guimarães, Christian Hirsch, Leonardo P. Mesquita, Camila C. Abreu, Christiane M.B.M. Rocha, Flademir Wouters, Moisés C. Moreira
Pesquisa Veterinária Brasileira.2011; 31(1): 53.     CrossRef
Detecção de anticorpos anti-Neospora caninum em amostras individuais e coletivas de leite de bovinos pela reação de imunofluorescência indireta
Giovana Camillo, Alfredo Skrebsky Cezar, Ana Maria Antonello, Luís Antônio Sangioni, Eduardo Furtado Flores, Gabriel Ribas Pereira, Paulo Bayard Dias Gonçalves, Fernanda Silveira Flôres Vogel
Pesquisa Veterinária Brasileira.2011; 31(6): 482.     CrossRef
Sheep abortion associated with Neospora caninum in Mato Grosso do Sul, Brazil
Ana Paula Pinto, Flávia B. Bacha, Bethania S. Santos, David Driemeier, Nadia A.B. Antoniassi, Nickolly L.K. de Sá Ribas, Ricardo A.A. Lemos
Pesquisa Veterinária Brasileira.2012; 32(8): 739.     CrossRef
Neospora caninum em bovinos em matadouros de Pernambuco e Alagoas
Rodolfo L.G. Amaral, Leonildo B.G. Silva, José W. Pinheiro Júnior, Orestes L. Souza Neto, Carlos A.S. Leal, Wagnner J.N. Porto, José M.P. Barbosa, Rinaldo A. Mota
Pesquisa Veterinária Brasileira.2012; 32(10): 953.     CrossRef
Abortos por Neosporacaninum em bovinos do sul de Minas Gerais
Débora R. Orlando, Rafael C. Costa, Bruno A. Soares, Natália S.C. Oliveira, Lismara C. Nascimento, Ana P. Peconick, Djeison L. Raymundo, Mary S. Varaschin
Pesquisa Veterinária Brasileira.2013; 33(11): 1332.     CrossRef
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Pedro S. Quevedo, Luciana F.C. Avila, Andréia Saggin, Tony R. Silveira, Lorena S. Feijó, Friedrich Frey Jr, Bruna R. Curcio, Nara Amélia R. Farias
Pesquisa Veterinária Brasileira.2015; 35(1): 29.     CrossRef
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Luiza P. Portella, Gustavo C. Cadore, Marcelo de Lima, Luís A. Sangioni, Geferson Fischer, Fernanda S.F. Vogel
Pesquisa Veterinária Brasileira.2016; 36(10): 947.     CrossRef
Anticorpos anti-Neospora caninum em bovinos de leite do sudoeste do estado do Paraná
G Camillo, G Cadore, A.S Cezar, G Toscan, P Bräunig, L.A Sangioni, F.S.F Vogel
Arquivo Brasileiro de Medicina Veterinária e Zootecnia.2010; 62(6): 1511.     CrossRef
Anticorpos anti-Neospora caninum em bovinos, ovinos e bubalinos no Estado do Rio Grande do Sul
Fernanda Silveira Flôres Vogel, Sandra Arenhart, Fernando Viçosa Bauermann
Ciência Rural.2006; 36(6): 1948.     CrossRef
Suscetibilidade de linhagens celulares e cultivos primários ao Neospora caninum
Gustavo Cauduro Cadore, Fernanda Silveira Flores Vogel, Eduardo Furtado Flores, Luis Antônio Sangioni, Giovana Camillo
Ciência Rural.2009; 39(5): 1581.     CrossRef
Pesquisa de anticorpos anti-Neospora spp. e anti-herpersvírus equino em cavalos de tração no município de Santa Maria, RS, Brasil
Luís Antonio Sangioni, Sônia de Avila Botton, Juliana Felipetto Cargnelutti, Gustavo Cauduro Cadore, Alfredo Skrebsky Cezar, Rudi Weiblen, Sonia Terezinha Anjos Lopes, Fernanda Silveira Flores Vogel
Ciência Rural.2011; 41(2): 321.     CrossRef
Reação de imunofluorescência indireta para detecção de anticorpos anti-Neospora caninum em amostras coletivas de leite
Giovana Camillo, Ana Maria Antonello, Gabriel Ribas Pereira, Paulo Bayard Dias Gonçalves, Luís Antônio Sangioni, Lilian Muller, Fernanda Silveira Flores Vogel
Ciência Rural.2011; 41(9): 1600.     CrossRef
Screening for Toxoplasma gondii in aborted bovine fetuses in Brazil
A.D. Cabral, C.N. Camargo, N.T.C. Galleti, L.H. Okuda, E.M. Pituco, C. Del Fava
Arquivos do Instituto Biológico.2013; 80(1): 103.     CrossRef
Prevalence of anti-Neospora caninum antibodies in cattle from the state of Mato Grosso do Sul, Brazil
Leandra M. Oshiro, Maria de Fatima C. Matos, Jacqueline M. de Oliveira, Letícia A.R.C. Monteiro, Renato Andreotti
Revista Brasileira de Parasitologia Veterinária.2007; 16(3): 133.     CrossRef
Frequency of antibodies against Neospora caninum in stray and domiciled dogs from urban, periurban and rural areas from Paraná State, Southern Brazil
Nicolle Fridlund-Plugge, Fabiano Montiani-Ferreira, Rosária R. T. B. Richartz, Juliano Dal Pizzol, Pedro C. Machado Jr, Lia F. L. Patrício, Adriana S. Rosinelli, Rosangela Locatelli-Dittrich
Revista Brasileira de Parasitologia Veterinária.2008; 17(4): 222.     CrossRef
Prevalence of Neospora caninum antibodies in sheep flocks of Uberlândia county, MG
Sandra Renata Sampaio Salaberry, Liria Hiromi Okuda, Alessandra Figueiredo de Castro Nassar, Jacqueline Ribeiro de Castro, Anna Monteiro Correia Lima-Ribeiro
Revista Brasileira de Parasitologia Veterinária.2010; 19(3): 148.     CrossRef
Occurrence of antibodies against Neospora caninum and/or Toxoplasma gondii in dogs with neurological signs
Nicolle Fridlund Plugge, Fabiano Montiani Ferreira, Rosária Regina Tesoni de Barros Richartz, Adriana de Siqueira, Rosangela Locatelli Dittrich
Revista Brasileira de Parasitologia Veterinária.2011; 20(3): 202.     CrossRef
Serological survey of Neospora caninum in small ruminants from Pernambuco State, Brazil
Antonio Amélia Santos Mucalane Tembue, Rafael Antonio de Nascimento Ramos, Thais Rabelo de Sousa, Alessandra Ribeiro Albuquerque, Alvimar José da Costa, Isabelle Maria Jaqueline Meunier, Maria Aparecida da Gloria Faustino, Leucio Câmara Alves
Revista Brasileira de Parasitologia Veterinária.2011; 20(3): 246.     CrossRef
Neospora caninum in bovine fetuses of Minas Gerais, Brazil: genetic characteristics of rDNA
Domingos Sávio dos Santos, Michele Placedino Andrade, Mary Suzan Varaschin, Antônio Marcos Guimarães, Christian Hirsch
Revista Brasileira de Parasitologia Veterinária.2011; 20(4): 281.     CrossRef
Occurrence of anti-Neospora caninum and anti-Toxoplasma gondii IgG antibodies in goats and sheep in western Maranhão, Brazil
Larissa Martins de Brito Moraes, Juliana Macedo Raimundo, Andresa Guimarães, Huarrisson Azevedo Santos, Gilberto de Lima Macedo Junior, Carlos Luiz Massard, Rosangela Zacarias Machado, Cristiane Divan Baldani
Revista Brasileira de Parasitologia Veterinária.2011; 20(4): 312.     CrossRef
Detection of Neospora sp. antibodies in cart horses from urban areas of Curitiba, Southern Brazil
Eliana Monteforte Cassaro Villalobos, Keiko Endo Furman, Maria do Carmo Custódio de Souza Hunold Lara, Elenice Maria Sequetin Cunha, Mariane Angélica Finger, Ana Paula Brenner Busch, Ivan Roque de Barros Filho, Ivan Deconto, Peterson Triches Dornbusch, Al
Revista Brasileira de Parasitologia Veterinária.2012; 21(1): 68.     CrossRef
Seroprevalence of antibodies to Neospora caninum in dogs in the state of Alagoas, Brazil
Maria Evódia de Sousa, Wagnner José Nascimento Porto, Pedro Paulo Feitosa de Albuquerque, Orestes Luiz de Souza Neto, José Wilton Pinheiro Júnior, Rinaldo Aparecido Mota
Revista Brasileira de Parasitologia Veterinária.2012; 21(3): 287.     CrossRef
Quantification of vertical transmission of Neospora caninum in dairy cows in Minas Gerais, Brazil
Raquel Ribeiro Dias Santos, Christiane Maria Barcellos Magalhães da Rocha, Tarcísio de Morais Gonçalves, Antônio Marcos Guimarães
Revista Brasileira de Parasitologia Veterinária.2012; 21(3): 294.     CrossRef
Occurrences of anti-Toxoplasma gondiiand anti-Neospora caninum antibodies in Barbary sheep at Curitiba zoo, southern Brazil
Vivien Midori Morikawa, Cristina Kraemer Zimpel, Igor Adolfo Dexheimer Paploski, Maria do Carmo Custódio de Souza Hunold Lara, Eliana Monteforte Cassaro Villalobos, Adriana Hellmeister de Campos Nogueira Romaldini, Liria Hiromi Okuda, Alexander Welker Bio
Revista Brasileira de Parasitologia Veterinária.2014; 23(2): 255.     CrossRef
Seroprevalence and risk factors for Neospora caninum in goats in Santa Catarina state, Brazil
Josué Pires Topazio, Augusto Weber, Giovana Camillo, Fernanda Flores Vogel, Gustavo Machado, André Ribeiro, Anderson Barbosa Moura, Leandro Sâmia Lopes, Alexandre Alberto Tonin, Natan Marcos Soldá, Patrícia Bräunig, Aleksandro Schafer da Silva
Revista Brasileira de Parasitologia Veterinária.2014; 23(3): 360.     CrossRef
Antibodies to Neospora caninum in sheep from slaughterhouses in the state of São Paulo, Brazil
Laís Moraes Paiz, Rodrigo Costa da Silva, Benedito Donizete Menozzi, Helio Langoni
Revista Brasileira de Parasitologia Veterinária.2015; 24(1): 95.     CrossRef
Risk factors for Toxoplasma gondii and Neospora caninum seropositivity in buffaloes in Paraiba State, Brazil
Arthur Willian de Lima Brasil, Roberta Nunes Parentoni, Thais Ferreira Feitosa, Camila de Sousa Bezerra, Vinicius Longo Ribeiro Vilela, Hilda Fátima de Jesus Pena, Sergio Santos de Azevedo
Revista Brasileira de Parasitologia Veterinária.2015; 24(4): 459.     CrossRef
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Cesar Augusto Barbosa de Macedo, Madlaine Frigo Silveira Barbosa de Macedo, Ana Carolina Miura, Alessandra Taroda, Sergio Tosi Cardim, Elisabeth Ann Innes, Frank Katzer, German Jose Cantón, Francesca Chianini, Selwyn Arlington Headley, João Luis Garcia
Revista Brasileira de Parasitologia Veterinária.2017; 26(3): 292.     CrossRef
Risk factors and anti-Toxoplasma gondii and Neospora caninum antibody occurrence in dogs in João Pessoa, Paraíba state, Northeastern Brazil
Arthur Willian de Lima Brasil, Roberta Nunes Parentoni, José Givanildo da Silva, Carolina de Sousa Américo Batista Santos, Rinaldo Aparecido Mota, Sérgio Santos de Azevedo
Revista Brasileira de Parasitologia Veterinária.2018; 27(2): 242.     CrossRef
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Marcos Enrique Serrano-Martínez, Cesar Abel Burga Cisterna, Roberto Carlos Evaristo Romero, Marco Antonio Quispe Huacho, Alessandra Matienzo Bermabé, Luis Antonio Llanco Albornoz
Revista Brasileira de Parasitologia Veterinária.2019; 28(2): 215.     CrossRef
Seroprevalence and incidence of Toxoplasma gondii and Neospora caninum infection in naturally exposed domestic dogs from a rural area of São Paulo state, Brazil
Anaiá da Paixão Sevá, Daniela Pontes Chiebao, Ana Perola Drulla Brandão, Silvia Neri Godoy, Tatiana Jimenez-Villegas, Hilda Fátima Jesus Pena, Fernando Ferreira
Revista Brasileira de Parasitologia Veterinária.2020;[Epub]     CrossRef
Serological evaluation of Neospora caninum in pregnant women treated at referral center for prenatal screening in Mato Grosso do Sul, Brazil
Pâmella Oliveira Duarte, Bárbara Guimarães Csordas, Leandra Marla Oshiro, Leandro de Oliveira Souza Higa, Namor Pinheiro Zimmermann, Kauê Rodriguez Martins, Jacqueline Cavalcante Barros, Renato Andreotti
Revista Brasileira de Parasitologia Veterinária.2020;[Epub]     CrossRef
Occurrence of IgG antibodies against Toxoplasma gondii, Neospora caninum, and Leptospira spp. in goats and sheep from an indigenous village in Pernambuco, Brazil
Cynthia Maria Morais de Queiroz Galvão, Pollyanne Raysa Fernandes de Oliveira, André Luiz de Aguiar Cavalcanti, Denise Batista Nogueira, Sérgio Santos de Azevedo, Rafael Antônio do Nascimento Ramos, Rinaldo Aparecido Mota
Revista Brasileira de Parasitologia Veterinária.2023;[Epub]     CrossRef
Gene Cloning and Characterization of the Protein Encoded by theNeospora caninumBradyzoite-Specific Antigen GeneBag1
T. Kobayashi, S. Narabu, Y. Yanai, Y. Hatano, A. Ito, S. Imai, K. Ike
Journal of Parasitology.2013; 99(3): 453.     CrossRef
Oxidative Stress in Brain Tissue of Gerbils Experimentally Infected withNeospora caninum
Alexandre A Tonin, Aleksandro S. da Silva, Gustavo R. Thomé, Guilherme V. Bochi, Maria R. C. Schetinger, Rafael N. Moresco, Giovana Camillo, Gustavo Toscan, Fernanda F. Vogel, Sonia T. A. Lopes
Journal of Parasitology.2014; 100(1): 154.     CrossRef
Prevalence of Neospora caninum and Toxoplasma gondii Antibodies in Wild Ruminants From the Countryside or Captivity in the Czech Republic
E. Bartova, K. Sedlak, I. Pavlik, I. Literak
Journal of Parasitology.2007; 93(5): 1216.     CrossRef
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Sangeetha Srinivasan, Joachim Mueller, Angela Suana, Andrew Hemphill
Journal of Parasitology.2007; 93(5): 1046.     CrossRef
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Hui-Yan Xia, Dong-Hui Zhou, Kun Jia, Xian-Bin Zeng, Dun-Wei Zhang, Li-Xuan She, Rui-Qing Lin, Zi-Guo Yuan, Shou-Jun Li, Xing-Quan Zhu
Journal of Parasitology.2011; 97(1): 172.     CrossRef
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N. Pusterla, P. A. Conrad, A. E. Packham, S. M. Mapes, C. J. Finno, I. A. Gardner, B. C. Barr, G. L. Ferraro, W. D. Wilson
Journal of Parasitology.2011; 97(2): 281.     CrossRef
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Ioan Liviu Mitrea, Violeta Enachescu, Ruxandra Radulescu, Mariana Ionita
Journal of Parasitology.2012; 98(1): 69.     CrossRef
RISK OF TRANSPLACENTAL TRANSMISSION OF SARCOCYSTIS NEURONA AND NEOSPORA HUGHESI IN CALIFORNIA HORSES
Paulo C. Duarte, Patricia A. Conrad, Bradd C. Barr, W. David Wilson, Gregory L. Ferraro, Andrea E. Packham, Tim E. Carpenter, Ian A. Gardner
Journal of Parasitology.2004; 90(6): 1345.     CrossRef
TRANSMISSION OF NEOSPORA CANINUM BETWEEN WILD AND DOMESTIC ANIMALS
L. F P. Gondim, M. M. McAllister, N. E. Mateus-Pinilla, W. C. Pitt, L. D. Mech, M. E. Nelson
Journal of Parasitology.2004; 90(6): 1361.     CrossRef
ADAPTATION OF NEOSPORA CANINUM ISOLATES TO CELL-CULTURE CHANGES: AN ARGUMENT IN FAVOR OF ITS CLONAL POPULATION STRUCTURE
F. J. Pérez-Zaballos, L. M. Ortega-Mora, G. Álvarez-García, E. Collantes-Fernández, V. Navarro-Lozano, L. García-Villada, E. Costas
Journal of Parasitology.2005; 91(3): 507.     CrossRef
Prevalence of Antibodies to Neospora caninum in Wild Animals
J. P. Dubey, P. Thulliez*
Journal of Parasitology.2005; 91(5): 1217.     CrossRef
SEROLOGIC SURVEY FOR TOXOPLASMA GONDII AND NEOSPORA CANINUM IN THE COMMON BRUSHTAIL POSSUM (TRICHOSURUS VULPECULA) FROM URBAN SYDNEY, AUSTRALIA
Jutta Eymann, Catherine A. Herbert, Desmond W. Cooper, J. P. Dubey
Journal of Parasitology.2006; 92(2): 267.     CrossRef
MULTILOCUS MICROSATELLITE ANALYSIS REVEALS EXTENSIVE GENETIC DIVERSITY IN NEOSPORA CANINUM
Javier Regidor-Cerrillo, Susana Pedraza-Díaz, Mercedes Gómez-Bautista, Luis M. Ortega-Mora
Journal of Parasitology.2006; 92(3): 517.     CrossRef
COMPARATIVE EFFECT OF NEOSPORA CANINUM INFECTION IN BALB/c MICE AT THREE DIFFERENT GESTATION PERIODS
Inmaculada C. López-Pérez, Verónica Risco-Castillo, Esther Collantes-Fernández, Luis Miguel Ortega-Mora
Journal of Parasitology.2006; 92(6): 1286.     CrossRef
NEOSPORA CANINUM–LIKE OOCYSTS OBSERVED IN FECES OF FREE-RANGING RED FOXES (VULPES VULPES) AND COYOTES (CANIS LATRANS)
Wendela Wapenaar, Mark C. Jenkins, Ryan M. O'Handley, Herman W. Barkema
Journal of Parasitology.2006; 92(6): 1270.     CrossRef
First Report of Neospora Caninum Abortion in a Beef Cow–Calf Herd From Andorra, Europe
Ramon Armengol, Marcela Pabón, Carles Adelantado, Fernando López-Gatius, Sonia Almería
Journal of Parasitology.2006; 92(6): 1361.     CrossRef
The prevalence of Toxoplasma gondiiIgM and IgG antibodies in dogs and cats from the Czech Republic
K. Sedlak, E. Bartova
Veterinární medicína.2006; 51(12): 555.     CrossRef
Toxoplasma gondii and Neospora caninum antibodies in goats in the Czech Republic
E. Bartova, K. Sedlak
Veterinární medicína.2012; 57(3): 111.     CrossRef
Effects of Neospora caninum on reproductive performance and the efficacy of treatment with a combination of sulphadiazine-trimethoprim and toltrazuril: a longitudinal field study
H.E. Canatan, I.M. Polat, R. Bayramoglu, S. Kuplulu, M.R. Vural, E. Aktug
Veterinární medicína.2014; 59(1): 22.     CrossRef
Neospora caninum in Aborted Bovine Fetuses in Trakya Region, Turkey - Histopathological, Immunohistochemical and Molecular Detection
Ozge Erdogan Bamac, Damla Haktanir, Handan Çetinkaya, Gülay Yuzbasioglu Özturk, Aydın Gurel, Aslı Mete
Acta Scientiae Veterinariae.2022;[Epub]     CrossRef
Neosporosis and Visceral Leishmaniosis in a Dog in Central–West Brazil
Bianca Ribas Sena, Maria Sabrina de Freitas, Maria Natália de Freitas, Arleana do Bom Parto Ferreira de Almeida, Valéria Régia Franco Sousa
Acta Veterinaria.2024; 74(4): 573.     CrossRef
Diagnosis of bovine neosporosis: Recent advances and perspectives
Luis Ortega-Mora, Aurora Fernández-García, Mercedes Gómez-Bautista
Acta Parasitologica.2006; 51(1): 1.     CrossRef
Neospora caninum and neosporosis — recent achievements in host and parasite cell biology and treatment
Andrew Hemphill, Bruno Gottstein
Acta Parasitologica.2006;[Epub]     CrossRef
Characterization of the first Polish isolate of Neospora caninum from cattle
Katarzyna Goździk, Władysław Cabaj
Acta Parasitologica.2007;[Epub]     CrossRef
First in vitro isolation of Neospora caninum from a naturally infected adult dairy cow in Slovakia
Katar?na Reiterov?, Silvia ?pilovsk?, Andrea ?ob?diov?, Rastislav Mucha
Acta Parasitologica.2011;[Epub]     CrossRef
Seroprevalence of Toxoplasma gondii and Neospora caninum in dogs from Korea
Thuy Nguyen, Se-Eun Choe, Jae-Won Byun, Hong-Bum Koh, Hee-Soo Lee, Seung-Won Kang
Acta Parasitologica.2012;[Epub]     CrossRef
PCR detection of Neospora caninum in water buffalo foetal tissues
Clementina Auriemma, Maria Lucibelli, Giorgia Borriello, Esterina Carlo, Alessandra Martucciello, Lorena Schiavo, Amalia Gallo, Francesca Bove, Federica Corrado, Santa Girardi, Maria Amoroso, Barbara ?egli Uberti, Giorgio Galiero
Acta Parasitologica.2014; 59(1): 1.     CrossRef
Anti-Sarcocystis Antibodies in Lambs Deprived of Colostrum
Camila Encarnação Minuzzi, Fernando de Souza Rodrigues, Camila Balconi Marques, Tiago Gallina, Thiago Cardoso dos Santos, Luiza Pires Portella, Patricia Bräunig, Alisson Rodrigues Döhler, Luis Antonio Sangioni, Fernanda Silveira Flores Vogel
Acta Parasitologica.2020; 65(1): 256.     CrossRef
Seroprevalence of Neospora caninum Infection in Dog Population Worldwide: A Systematic Review and Meta-analysis
Davood Anvari, Reza Saberi, Mehdi Sharif, Shahabbedin Sarvi, Seyed Abdollah Hosseini, Mahmood Moosazadeh, Zahra Hosseininejad, Tooran Nayeri Chegeni, Ahmad Daryani
Acta Parasitologica.2020; 65(2): 273.     CrossRef
The role of the colostrum and milk in Neospora caninum transmission
B. Moskwa, W. Cabaj
Helminthologia.2007; 44(3): 126.     CrossRef
Investigation of Toxoplasma gondii and Neospora caninum in different tissues of aborted foetuses of sheep in Van Province, Türkiye: Analysis by nested PCR, histopathological and immunohistochemical methods
Özlem Orunç Kılınç, Adnan Ayan, Nihat Yumuşak, Ahmet Ufuk Kömüroğlu, Burçak Aslan, Özgür Yaşar Çelik, Yaşar Göz
Acta Veterinaria Brno.2023; 92(2): 123.     CrossRef
The incidence of Neospora caninum in dairy cows with abortion and infertility problems
Gaye BULUT, Hikmet ÜN, Gökçenur SANİOĞLU, İlker CAMKERTEN
Kocatepe Veterinary Journal.2021;[Epub]     CrossRef
Investigation of anti-Neospora caninum Antibodies in Goats in Mesudiye District of Ordu using ELISA
Deniz ÖZDAMAR, Bilge KARATEPE, Alparslan YILDIRIM
Kocatepe Veterinary Journal.2020;[Epub]     CrossRef
The seroprevalence and risk factors associated with bovine neosporosis (Neosporum caninum) in Belisario Quevedo, Cotopaxi-Ecuador
V. R. Herrera-Yunga, C. F. Beltrán-Romero, G. I. Vera-Guanoluisa, J. S. Yaguana-Jiménez, Y. P. Esquivel-Tipan
Revista Veterinaria.2025; 36(1): 1.     CrossRef
Etymologia: Neospora caninum
Ronnie Henry
Emerging Infectious Diseases.2019; 25(6): 1228.     CrossRef
ELISA detection of IgG antibody against a recombinant major surface antigen (Nc-p43) fragment of Neospora caninum in bovine sera
Hye-Jin Ahn, Sera Kim, Dae-Yong Kim, Ho-Woo Nam
The Korean Journal of Parasitology.2003; 41(3): 175.     CrossRef
Seroprevalence of antibodies to Neospora caninum in dogs and raccoon dogs in Korea
Jae-Hoon Kim, Min-Soo Kang, Byung-Chun Lee, Woo-Suk Hwang, Chang-Woo Lee, Byung-Jae So, J. P. Dubey, Dae-Yong Kim
The Korean Journal of Parasitology.2003; 41(4): 243.     CrossRef
Protective efficacy of vaccination with Neospora caninum multiple recombinant antigens against experimental Neospora caninum infection
Jung-Hwa Cho, Woo-Suk Chung, Kyoung-Ju Song, Byoung-Kuk Na, Seung-Won Kang, Chul-Yong Song, Tong-Soo Kim
The Korean Journal of Parasitology.2005; 43(1): 19.     CrossRef
Loss of infectivity of Neospora caninum oocysts maintained for a prolonged time
Rosangela Soares Uzeda, Kattyanne De Souza Costa, Sara Lima Santos, Alexandre Moraes Pinheiro, Maria Angela Ornelas De Almeida, Milton M. McAllister, Luis Fernando Pita Gondim
The Korean Journal of Parasitology.2007; 45(4): 295.     CrossRef
Bibliometric Analysis of the Korean Journal of Parasitology: Measured from SCI, PubMed, Scopus, and Synapse Databases
Choon Shil Lee
The Korean Journal of Parasitology.2009; 47(Suppl): S155.     CrossRef
Congenital Neosporosis in Goats from the State of Minas Gerais, Brazil
Mary S. Varaschin, Christian Hirsch, Flademir Wouters, Karen Y. Nakagaki, Antônio M. Guimarães, Domingos S. Santos, Pedro S. Bezerra, Rafael C. Costa, Ana P. Peconick, Ingeborg M. Langohr
The Korean Journal of Parasitology.2012; 50(1): 63.     CrossRef
Seroprevalence of Toxoplasma gondii and Neospora caninum in camels recently imported to Egypt from Sudan and a global systematic review
Ragab M. Fereig, Hanan H. Abdelbaky, El-Sayed El-Alfy, Mohamed El-Diasty, Ahmed Elsayed, Hassan Y. A. H. Mahmoud, Alsagher O. Ali, Abdulrahman Ahmed, Ehab Mossaad, Abdullah F. Alsayeqh, Caroline F. Frey
Frontiers in Cellular and Infection Microbiology.2022;[Epub]     CrossRef
Canine Neutrophil Extracellular Traps Release Induced by the Apicomplexan Parasite Neospora caninum In Vitro
Zhengkai Wei, Carlos Hermosilla, Anja Taubert, Xuexiu He, Xiaocen Wang, Pengtao Gong, Jianhua Li, Zhengtao Yang, Xichen Zhang
Frontiers in Immunology.2016;[Epub]     CrossRef
Bovine Polymorphonuclear Neutrophils Cast Neutrophil Extracellular Traps against the Abortive Parasite Neospora caninum
Rodolfo Villagra-Blanco, Liliana M. R. Silva, Tamara Muñoz-Caro, Zhengtao Yang, Jianhua Li, Ulrich Gärtner, Anja Taubert, Xichen Zhang, Carlos Hermosilla
Frontiers in Immunology.2017;[Epub]     CrossRef
Caprine Monocytes Release Extracellular Traps against Neospora caninum In Vitro
Zhengtao Yang, Zhengkai Wei, Carlos Hermosilla, Anja Taubert, Xuexiu He, Xiaocen Wang, Pengtao Gong, Jianhua Li, Xichen Zhang
Frontiers in Immunology.2018;[Epub]     CrossRef
Neurological Infection, Kynurenine Pathway, and Parasitic Infection by Neospora caninum
Ana Elisa Del’Arco, Deivison Silva Argolo, Gilles Guillemin, Maria de Fátima Dias Costa, Silvia Lima Costa, Alexandre Moraes Pinheiro
Frontiers in Immunology.2022;[Epub]     CrossRef
Activation of ERK Signaling via TLR11 Induces IL-12p40 Production in Peritoneal Macrophages Challenged by Neospora caninum
Xiaoxia Jin, Pengtao Gong, Xichen Zhang, Guojiang Li, Tao Zhu, Mengge Zhang, Jianhua Li
Frontiers in Microbiology.2017;[Epub]     CrossRef
Activation of a Neospora caninum EGFR-Like Kinase Facilitates Intracellular Parasite Proliferation
Xiaoxia Jin, Guojiang Li, Xichen Zhang, Pengtao Gong, Yanhui Yu, Jianhua Li
Frontiers in Microbiology.2017;[Epub]     CrossRef
14-3-3 Protein of Neospora caninum Modulates Host Cell Innate Immunity Through the Activation of MAPK and NF-κB Pathways
Shan Li, Pengtao Gong, Nan Zhang, Xin Li, Lixin Tai, Xu Wang, Zhengtao Yang, Ju Yang, Xingquan Zhu, Xichen Zhang, Jianhua Li
Frontiers in Microbiology.2019;[Epub]     CrossRef
Congenital Transmission of Apicomplexan Parasites: A Review
Maura Rojas-Pirela, Lisvaneth Medina, Maria Verónica Rojas, Ana Isabel Liempi, Christian Castillo, Elizabeth Pérez-Pérez, Jesús Guerrero-Muñoz, Sebastian Araneda, Ulrike Kemmerling
Frontiers in Microbiology.2021;[Epub]     CrossRef
Molecular detection and identification of three intracellular parasites of retail mutton products in Beijing, China
Zifu Zhu, Yajie Chen, Xu Yang, Lifang Wang, Qun Liu, Jing Liu
Frontiers in Veterinary Science.2022;[Epub]     CrossRef
Development and application of an indirect ELISA to detect antibodies to Neospora caninum in cattle based on a chimeric protein rSRS2-SAG1-GRA7
Cong-Shan Yang, Chuan-Yin Yang, Olalekan-Opeyemi Ayanniyi, Ya-Qian Chen, Zhen-Xiao Lu, Jin-Yi Zhang, Lu-Yao Liu, Yu-Hang Hong, Rong-Rong Cheng, Xiang Zhang, Qin-Qin Zong, Hong-Xi Zhao, Qian-Ming Xu
Frontiers in Veterinary Science.2022;[Epub]     CrossRef
The Global Prevalence of Neospora caninum Infection in Sheep and Goats That Had an Abortion and Aborted Fetuses: A Systematic Review and Meta-Analysis
Tooran Nayeri, Shahabeddin Sarvi, Mahmood Moosazadeh, Ahmad Daryani
Frontiers in Veterinary Science.2022;[Epub]     CrossRef
Seroprevalence and risk factors of Toxoplasma gondii and Neospora caninum infection in black goats in Yunnan Province, Southwestern China
Xiao-Hui Hu, Shi-Chen Xie, Qin-Li Liang, Li-Xiu Sun, Zhao Li, Jian-Fa Yang, Xing-Quan Zhu, Feng-Cai Zou, Jun-Jun He
Frontiers in Veterinary Science.2022;[Epub]     CrossRef
Serosurvey of selected reproductive pathogens in domestic ruminants from Upper Egypt
Shimaa Ismail Farag, David Cano-Terriza, Moisés Gonzálvez, Doaa Salman, Nasr-Eldin M. Aref, Murad A. Mubaraki, Débora Jiménez-Martín, Ignacio García-Bocanegra, Ehab Kotb Elmahallawy
Frontiers in Veterinary Science.2023;[Epub]     CrossRef
Socio-economic assessment of dog population management systems: a scoping review
Rabina Ghimire, Parimala Mohanty, Elly Hiby, Andrew Larkins, Salome Dürr, Sonja Hartnack
Frontiers in Veterinary Science.2025;[Epub]     CrossRef
Vaccines against a Major Cause of Abortion in Cattle, Neospora caninum Infection
Thierry Monney, Karim Debache, Andrew Hemphill
Animals.2011; 1(3): 306.     CrossRef
Serological Survey on the Occurrence of Rickettsia spp., Neospora caninum, Bartonella henselae and Toxoplasma gondii in Cats from Tuscany (Central Italy)
Valentina Virginia Ebani, Simona Nardoni, Michela Maestrini, Stefania Perrucci, Francesca Mancianti
Animals.2021; 11(6): 1842.     CrossRef
Prevalence of Neospora caninum Exposure in Wild Pigs (Sus scrofa) from Oklahoma with Implications of Testing Method on Detection
Katelyn M. Haydett, Steven T. Peper, Cynthia Reinoso Webb, Hannah S. Tiffin, Alexander N. Wilson-Fallon, Yava L. Jones-Hall, Stephen L. Webb, Steven M. Presley
Animals.2021; 11(9): 2487.     CrossRef
The Utility of Serological Analysis for Neospora caninum Infection in Dairy Cattle Farms Management: Serological Investigation and Evaluation of the Effects on Reproductive and Productive Performances in Two Study Herds in Northern Italy
Luca Villa, Alessia Libera Gazzonis, Emanuele Fumagalli, Sergio Aurelio Zanzani, Maria Teresa Manfredi
Animals.2022; 12(6): 786.     CrossRef
Ovine Neosporosis: The Current Global Situation
Julio Benavides, Marta González-Warleta, Noive Arteche-Villasol, Valentín Pérez, Mercedes Mezo, Daniel Gutiérrez-Expósito
Animals.2022; 12(16): 2074.     CrossRef
Seroprevalence and Risk Factors for Toxoplasma gondii and Neospora caninum in Cattle in Portugal
Helga Waap, Andrea Bärwald, Telmo Nunes, Gereon Schares
Animals.2022; 12(16): 2080.     CrossRef
Retrospective Molecular Survey on Bacterial and Protozoan Abortive Agents in Roe Deer (Capreolus capreolus) from Central Italy
Valentina Virginia Ebani, Chiara Trebino, Lisa Guardone, Fabrizio Bertelloni, Giulia Cagnoli, Iolanda Altomonte, Paolo Vignola, Paolo Bongi, Francesca Mancianti
Animals.2022; 12(22): 3202.     CrossRef
Serological Prevalence of Toxoplasma gondii, Neospora caninum, and Sarcoptes scabiei var. suis in Wild Boars (Sus scrofa) Hunted in a Highly Anthropized Area in Italy
Luca Villa, Carolina Allievi, Alessia Libera Gazzonis, Giordano Ventura, Matteo Gradassi, Sergio Aurelio Zanzani, Maria Teresa Manfredi
Animals.2023; 13(11): 1730.     CrossRef
Evaluation of Immunodiagnostic Performances of Neospora caninum Peroxiredoxin 2 (NcPrx2), Microneme 4 (NcMIC4), and Surface Antigen 1 (NcSAG1) Recombinant Proteins for Bovine Neosporosis
Ruenruetai Udonsom, Poom Adisakwattana, Supaluk Popruk, Onrapak Reamtong, Charoonluk Jirapattharasate, Tipparat Thiangtrongjit, Sarinya Rerkyusuke, Aran Chanlun, Tanjila Hasan, Manas Kotepui, Sukhontha Siri, Yoshifumi Nishikawa, Aongart Mahittikorn
Animals.2024; 14(4): 531.     CrossRef
Pinniped- and Cetacean-Derived ETosis Contributes to Combating Emerging Apicomplexan Parasites (Toxoplasma gondii, Neospora caninum) Circulating in Marine Environments
Rodolfo Villagra-Blanco, Liliana M. R. Silva, Iván Conejeros, Anja Taubert, Carlos Hermosilla
Biology.2019; 8(1): 12.     CrossRef
On the Biological and Genetic Diversity in Neospora caninum
Sarwat E. Al-Qassab, Michael P. Reichel, John T. Ellis
Diversity.2010; 2(3): 411.     CrossRef
Thiosemicarbazone Copper Chelator BLT-1 Blocks Apicomplexan Parasite Replication by Selective Inhibition of Scavenger Receptor B Type 1 (SR-BI)
Camilo Larrazabal, Sara López-Osorio, Zahady D. Velásquez, Carlos Hermosilla, Anja Taubert, Liliana M. R. Silva
Microorganisms.2021; 9(11): 2372.     CrossRef
Evaluation of a Commercial Serum Competitive Enzyme-Linked Immunosorbent Assay for Detection of Neospora caninum-Specific Antibodies in Raw Milk of Ruminants
Ragab M. Fereig, Sarah A. Altwaim, Caroline F. Frey
Parasitologia.2024; 4(2): 91.     CrossRef
Apicomplexan Protozoa Responsible for Reproductive Disorders: Occurrence of DNA in Blood and Milk of Donkeys (Equus asinus) and Minireview of the Related Literature
Stefania Perrucci, Lisa Guardone, Iolanda Altomonte, Federica Salari, Simona Nardoni, Mina Martini, Francesca Mancianti
Pathogens.2021; 10(2): 111.     CrossRef
Microneme Protein 6 Is Involved in Invasion and Egress by Neospora caninum
Xianmei Wang, Di Tang, Fei Wang, Gaowei Jin, Lifang Wang, Qun Liu, Jing Liu
Pathogens.2021; 10(2): 201.     CrossRef
Prevalence of Neospora caninum and Toxoplasma gondii Antibodies and DNA in Raw Milk of Various Ruminants in Egypt
Ragab M. Fereig, Hanan H. Abdelbaky, Amira M. Mazeed, El-Sayed El-Alfy, Somaya Saleh, Mosaab A. Omar, Abdullah F. Alsayeqh, Caroline F. Frey
Pathogens.2022; 11(11): 1305.     CrossRef
From Signaling Pathways to Distinct Immune Responses: Key Factors for Establishing or Combating Neospora caninum Infection in Different Susceptible Hosts
Ragab M. Fereig, Yoshifumi Nishikawa
Pathogens.2020; 9(5): 384.     CrossRef
Impact of Neospora caninum Infection on the Bioenergetics and Transcriptome of Cerebrovascular Endothelial Cells
Hany M. Elsheikha, Mamdowh Alkurashi, Suzy Palfreman, Marcos Castellanos, Kenny Kong, Evita Ning, Nashwa A. Elsaied, Kalotina Geraki, William MacNaughtan
Pathogens.2020; 9(9): 710.     CrossRef
Seroepidemiological Survey of Anti-Toxoplasma gondii and Anti-Neospora caninum Antibodies in Domestic Cats (Felis catus) in Rolim de Moura, State of Rondônia, North Brazil
Ana Luzia Peixoto Silva, Estefany Ferreira Lima, Geraldo Moreira Silva Filho, Larissa Claudino Ferreira, Beatriz de Andrade Campos, Ividy Bison, Arthur Willian de Lima Brasil, Roberta Nunes Parentoni, Thais Ferreira Feitosa, Vinícius Longo Ribeiro Vilela
Tropical Medicine and Infectious Disease.2023; 8(4): 220.     CrossRef
Exploiting the Macrophage Production of IL-12 in Improvement of Vaccine Development against Toxoplasma gondii and Neospora caninum Infections
Ragab M. Fereig, Mosaab A. Omar, Abdullah F. Alsayeqh
Vaccines.2022; 10(12): 2082.     CrossRef
Vertical and Horizontal Transmission of Neosporosis in Three Consecutive Pregnancies of Naturally Infected Pregnant Cows and the Effect of Vaccination on Abortion Rates
Sharon Tirosh-Levy, Elena Blinder, Daniel Yasur-Landau, Yaniv Lavon, Jacob Joost Doekes, Monica L. Mazuz
Vaccines.2025; 13(2): 131.     CrossRef
Vaccination with Neospora GRA6 Interrupts the Vertical Transmission and Partially Protects Dams and Offspring against Neospora caninum Infection in Mice
Ragab M. Fereig, Hanan H. Abdelbaky, Yoshifumi Nishikawa
Vaccines.2021; 9(2): 155.     CrossRef
Detection of Anti-Neospora caninum Antibodies on Dairy Cattle Farms in Southern Italy
Raffaella Manca, Giuseppina Ciccarese, Domenico Scaltrito, Daniela Chirizzi
Veterinary Sciences.2022; 9(2): 87.     CrossRef
Seroprevalence of Neospora caninum and Toxoplasma gondii Infections in Stray Dogs of Hamadan Suburb, West of Iran, 2018
Jamal Gharekhani, Mohammad Yakhchali, Ehsan Abbasi-Doulatshahi, Ehsan Barati
Avicenna Journal of Clinical Microbiology and Infection.2019; 6(2): 57.     CrossRef
Prevalence and Risk Factors Associated to Neospora caninum (Apicomplexa: Toxoplasmatidae) in Pet Dogs From Hamadan, West of Iran, 2016
Jamal Gharekhani, Mohammad Yakhchali, Reza Khaltabadi-Farahani
Avicenna Journal of Clinical Microbiology and Infection.2020; 7(1): 22.     CrossRef
Orta Karadeniz Bölgesindeki Sığır Atık Fetüslerinde Neospora Canınum’un Prevelansının PCR ile Taranması
Rahşan Koç Akpınar, Selma Kaya, Coşkun Aydın, Şakir Önder Türlek, Sema Nur Çelik
Etlik Veteriner Mikrobiyoloji Dergisi.2025; 35(2): 142.     CrossRef
Atık yapan sığırlarda Anti-Neospora caninum antikorlarının yaygınlığının araştırılması
Ufuk EROL, Erdem DANYER, Selim TUNCER, Çağla KORKMAZ, Ahmet DENİZ
Etlik Veteriner Mikrobiyoloji Dergisi.2019; 30(1): 78.     CrossRef
<italic>In vitro</italic> and <italic>in vivo</italic> efficacy of aurintricarboxylic acid against <italic>Neospora caninum</italic> infection
Zhengkai Wei, Yuxiao Qian, Xi Jiang, Yuqian Jiang, Rongsheng Huang, Kaifeng He, Jing Huang, Jiaxuan Wang, Xin Guo, Wenlong Huang, Dezhi Zhang, Zhengtao Yang, Quan Liu, Qianyong Li
Acta Biochimica et Biophysica Sinica.2025;[Epub]     CrossRef
Seroprevalence of Neospora caninum in Stray Dogs of Tabriz, Iran
Garedaghi Yagoob
Journal of Animal and Veterinary Advances.2012; 11(6): 723.     CrossRef
Stability analysis and optimal control of production-limiting disease in farm with two vaccines
Yue Liu, Wing-Cheong Lo
Discrete & Continuous Dynamical Systems - B.2022; 27(2): 619.     CrossRef
Seroprevalence of <i>Neospora caninum</i> in Sheep and Goats from Grenada, West Indies
Ravindra Nath Sharma, Jehna Bush, Keshaw Tiwari, Alfred Chikweto, Muhammad Iqbal Bhaiyat
Open Journal of Veterinary Medicine.2015; 05(11): 219.     CrossRef
Seroprevalence of Neospora caninum in Goats from Korkuteli District of Antalya
Mübeccel Atelge, Mustafa Karatepe, Alparslan Yıldırım
Turkish Journal of Parasitology.2022; 46(3): 180.     CrossRef
Nitric Oxide Production in mixed cultures of infected rats with Neospora caninum and treated with Jataí Honey (Tetragonisca angustula)
Ângela Cristina de Oliveira Lima, Luciana dos Santos Freitas, Carlos Alfredo Lopes De Carvalho, Alexandre Moraes Pinheiro
Archives of Health.2023; 4(1): 166.     CrossRef
Seroprevalence of Neospora caninum in Goats in Gevas District of Van
Ahmet TOY, Bekir OĞUZ
Manas Journal of Agriculture Veterinary and Life Sciences.2023; 13(1): 59.     CrossRef
Histopathologic Observation of the Aborted Fetus from Pregnant Dairy Cows Naturally Infected with Neospora caninum
Jeong-Hoon Son, Sung-Whan Cho
Journal of Life Science.2010; 20(10): 1556.     CrossRef
Neospora caninum: soroepidemiologia de vacas e cães de propriedades leiteiras de Cunha, São Paulo, Brasil
Sintia Barboza Bastos, Thais Agostinho Martins, Ana Sue Sammi, Felippe Danyel Cardoso Martins, Ivo Alexandre Leme da Cunha, Luiz Daniel de Barros, Dauton Luiz Zulpo, João Luis Garcia
Semina: Ciências Agrárias.2019; 40(6Supl2): 3123.     CrossRef
Soroprevalência de Toxoplasma gondii, Neospora caninum e Brucella abortus em ovinos de Toledo, Paraná, Brasil
Cristian André Bertuzzi, Evaldo Alan Weschenfelder, Douglas Adriano Webber, Thais Agostinho Martins, Beatriz Souza Lima Nino, Tiago André Frigotto, João Luis Garcia, Dauton Luiz Zulpo
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Abstract

Neospora caninum is a coccidian parasite of animals. It is a major pathogen for cattle and dogs and it occasionally causes clinical infections in horses, goats, sheep, and deer. Domestic dogs are the only known definitive hosts for N. caninum. It is one of the most efficiently transmitted parasite of cattle and up to 90% of cattle in some herds are infected. Transplacental transmission is considered the major route of transmission of N. caninum in cattle. Neospora caninum is a major cause of abortion in cattle in many countries. To elicit protective immunity against abortion in cows that already harbor a latent infection is a major problem. This paper reviews information on biology, diagnosis, epidemiology and control of neosporosis in animals.

INTRODUCTION

Since its first recognition in 1984 in dogs in Norway (Bjerkås et al., 1984) and the description of a new genus and species Neospora caninum (Dubey et al., 1988a), neosporosis has emerged as a serious disease of cattle and dogs worldwide. Additionally, clinical neosporosis has been reported in sheep, goats, deer, a rhinocerus, and horses and antibodies to N. caninum have been found in the sera of water buffaloes, red and gray foxes, coyotes, and camels, and felids.

BIOLOGY

Life Cycle

Dogs are both the intermediate and definitive host for N. caninum (McAllister et al., 1998; Lindsay et al., 1999a, 1990b, 2001a; Basso et al., 2001a; Dubey et al., 2002). The life cycle is typified by 3 infectious stages: tachyzoites, tissue cysts, and oocysts (Fig. 1 and Fig. 2). Tachyzoites and tissue cysts are the stages found in the intermediate hosts and they occur intracellularly (Dubey et al., 2002). Tachyzoites are approximately 6 × 2 μm (Fig. 1). Tissue cysts are often round or oval in shape, up to 107 μm long and are found primarily in the central nervous system (CNS). The tissue cyst wall is up to 4 μm thick and the enclosed bradyzoites are 7-8 × 2 μm. Thin-walled (0.3-1.0 μm) tissue cysts have been recently reported in muscles of cattle and dogs naturally-infected with a N. caninum-like parasite (Peters et al., 2001a). These intramuscular tissue cysts have not been yet found in experimentally-infected animals (Dubey et al., 2002).
Domestic dogs are the only known definitive host for N. caninum. N. caninum unsporulated oocysts from experimentally-infected dogs were 11.7 × 11.3 (10.6-12.4 × 10.6-12.0) μm in size (Lindsay et al., 1999a). N. caninum oocysts sporulate outside the host. N. caninum oocysts are morphologically similar to Toxoplasma gondii and Hammondia hammondi oocysts in cat feces and broadly resemble oocysts of Hammondia heydorni-like parasite in dog feces (Dubey et al., 2002). At the present, nothing is known regarding the frequency of shedding of oocysts, the survival of the oocysts in the environment, and whether other canids are also definitive hosts for N. caninum.

Transmission

Little is known about the mode of spread and tissue distribution of N. caninum in animals using the natural routes of transmission. The parasite can be transmitted transplacentally in several hosts and vertical route is the major mode of its transmission in cattle. Carnivores can acquire infection by ingestion of infected tissues (McAllister et al., 1998; Lindsay et al., 1999a, 1999b; Dijkstra et al. 2001; Schares et al., 2001; Gondim et al., 2002).
It is epidemiologically important to be able to identify N. caninum oocysts in dog feces. Microscopic examination alone will not be enough to identify N. caninum oocysts in dog feces. Methods have also been developed to genetically distinguish N. caninum oocysts from H. heydorni oocysts (Hill et al., 2001; Šlapeta et al., 2002). Neospora caninum oocysts have been identified feces of only two naturally-infected dogs (Basso et al., 2001a; Šlapeta et al., 2002).

Animal models

There are no suitable animal models at the present to perform bioassay to detect N. caninum oocysts in dog feces. Although interferon-gamma gene knockout (KO) mice are highly susceptible to parenteral inoculation with N. caninum tachyzoites and tissue cysts (Dubey and Lindsay, 1996; Dubey et al., 1998a), they are less susceptible to parenteral or oral inoculation with oocysts. Gerbils (Meriones unguiculatus) were susceptible to N. caninum infection with oocysts (Dubey and Lindsay, 2000; Basso et al., 2001a; Schares et al., 2001). Another species of gerbils, Meriones tristrami and sand rats (Psammoomys ubesus) also susceptible to tachyzoites infection (Pipano et al., 2002).

Comparison between neosporosis and toxoplasmosis

A large body of knowledge has been generated concerning biology of N. caninum because of previous experience with the related parasite, Toxoplasma gondii. Although N. caninum and T. gondii are very closely related parasites structurally, genetically, and immunologically, caution should be used in making generalizations about N. caninum based on the biology of T. gondii because neosporosis and toxoplasmosis are biologically distinct diseases. Toxoplasma gondii is a major disease of sheep and humans and not of cattle, whereas neosporosis is a major disease in cattle, not of sheep and there is no evidence for human infection.

NEOSPOROSIS IN CATTLE

Bovine neosporosis has been reviewed in several papers (Dubey and Lindsay, 1996; Wouda, 1998; Dubey, 1999; Anderson et al., 2000; Buxton et al., 2002; Dijkstra, 2002; Innes et al., 2002; Jenkins et al., 2002; Dubey, 2003). Therefore, most references on bovine neosporosis were omitted from this review.

Clinical signs

Neospora caninum causes abortion both dairy and beef cattle. Cows of any age may abort from 3 month gestation to term. Most neosporosis-induced abortions occur at 5-6 month gestation. Fetuses may die in utero, be resorbed, mummified, autolyzed, stillborn, born alive with clinical signs, or born clinically normal but chronically infected. Neosporosis-induced abortions occur year-round. Cows with N. caninum antibodies (seropositive) are more likely to abort than seronegative cows and this applies to both dairy and beef cattle. However, up to 95% of calves born congenitally-infected from seropositive dams remain clinically normal. The age of dam, lactation number, and history of abortion generally do not affect rate of congenital infection but there are reports indicating that in persistently infected cattle vertical transmission is more efficient in younger than older cows.
Clinical signs have only been reported in cattle younger than 2 month of age. Neospora caninum-infected calves may have neurologic signs, be underweight, unable to rise, or be born without clinical signs of disease. Hind limbs or forelimbs or both may be flexed or hyperextended. Neurologic examination may reveal ataxia, decreased patellar reflexes, and loss of conscious proprioception. Calves may have exophthalmia or asymmetrical appearance in the eyes. Neospora caninum occasionally causes birth defects including hydrocephalus and narrowing of the spinal cord.
Abortions may be epidemic or endemic (Wouda et al., 1999a). In infected areas, as many as 33% of dairy cow fetuses have been reported to abort within a few months. Abortions were considered epidemic if more than 10% of cows at risk aborted within 6-8 weeks. A small proportion (< 5%) of cows have been reported to have repeated abortion due to neosporosis (Anderson et al., 1995).

Prevalence

Neospora caninum infections have been reported from most parts of the world including Australia, New Zealand, Europe, Korea, Japan, Thailand, and the Americas. Neosporosis-associated bovine abortion and neonatal mortality has been reported from Argentina, Australia, Belgium, Brazil, Canada, Costa Rica, Denmark, France, Germany, Hungary, Ireland, Israel, Italy, Japan, Korea, Mexico, the Netherlands, New Zealand, Poland, Portugal, Spain, South Africa, Sweden, United Kingdom, USA, and Zimbabwe. Quantitative studies in the USA, New Zealand, the Netherlands, and Germany indicate that 12 to 42% of aborted fetuses from dairy cattle are infected with N. caninum (Table 1).
Serologic prevalence in cattle varies, depending on the country, region, type of serologic test used, and cut-off level used to determine the exposure. In some dairies up to 87% of cows are seropositive.

Diagnosis

Examination of the serum from an aborting cow is only indicative of exposure to N. caninum and histologic examination of the fetus is necessary for a definitive diagnosis of neosporosis. The brain, heart, liver, placenta, and body fluids or blood serum are the best specimens for diagnosis and diagnostic rates are higher if multiple tissues are examined. Although lesions of neosporosis are found in several organs, fetal brain is the most consistently affected organ. Because most aborted fetuses are likely to be autolyzed, even semi-liquid brain tissue should be fixed in 10% buffered neutral formalin for histologic examination of hematoxylin and eosin (HE) stained sections. Immunohistochemistry is necessary because there are generally only a few N. caninum present in autolyzed tissues and these are often not visible in H and E stained sections. The most characteristic lesion of neosporosis is focal encephalitis characterized by necrosis and nonsuppurative inflammation (Barr et al., 1991). Hepatitis is more common in epizootic than sporadic abortions. Lesions are also present in placenta but protozoa are difficult to find.
The efficiency of the diagnosis by PCR is dependent on the laboratory, stage of the autolysis of the fetus, and sampling procedures. Although immunohistochemical demonstration of N. caninum in lesions is the best evidence for etiology of abortion at the present time, it is very insensitive. Neospora caninum DNA can be detected by PCR in formalin-fixed, paraffin-embedded bovine aborted brain tissue.
Several serologic tests can be used to detect N. caninum antibodies including various ELISAs, the indirect fluorescent antibody test (IFAT), and the Neospora agglutination test (NAT). Immunoblots are useful in detecting N. caninum-specific antibodies. Avidity-ELISAs designed to distinguish recent and chronic infections in cattle appear promising to distinguish endemic and epidemic abortion.
Finding N. caninum antibody in serum from the fetus can establish N. caninum infection, but a negative result is not informative because antibody synthesis in the fetus is dependent on the stage of gestation, level of exposure, and the time between infection and abortion. Even a low IFAT titer of 1:25 should be regarded as specific for N. caninum infection, especially in fetuses. Immunoblotting using N. caninum specific antigen improves diagnosis. Although blood serum or any body fluid from the fetus may be used for serologic diagnosis, peritoneal fluid is better than other body fluids. In calves, presuckling serum can be submitted for diagnosis of congenital infection.
The definitive antibody level that should be considered diagnostic for neosporosis has not been established for bovines because of the uncertainty of serologic diagnosis in chronically infected animals and the availability of sera from noninfected cattle. In serological assays, titer and absorbance values are dependant on antigen composition, secondary antibodies and other reagents. Further, cut-off levels can be arbitrarily selected to provide sensitivity and specificity requested for a particular application. The age and class of an animal may also affect selection of a cut-off level. Although N. caninum is closely related to Toxoplasma gondii, Sarcocystis species, and other apicomplexans, cross reactivity has not been a major issue. Antibody titers in general are higher in cattle that have aborted due to neosporosis than those with normal pregnancy; however, titers in individual cows cannot determine etiology of abortions.
Toxoplasma gondii and Sarcocystis cruzi are 2 other protozoans that should be considered in the differential diagnosis of protozoal abortion in cattle. Immunohistochemical and detection of parasite DNA by PCR can distinguish them from N. caninum. Sarcocystis cruzi forms schizonts in vascular endothelium and is rarely (< 0.1%) found in aborted fetal brains, whereas N. caninum is usually located in extravascular tissues. Additionally, there are no immature schizonts in N. caninum infection in contrast with S. cruzi infections. Infection by T. gondii in bovine fetuses is rare (Canada et al., 2002b).
Attempts at isolation of viable N. caninum (Table 2) by bioassay in mice or cell culture have been largely unsuccessful and little is known of the antigenic variability among isolates of N. caninum, especially isolates from healthy animals. Many attempts to isolate viable N. caninum were unsuccessful because most N. caninum in fetuses die with the host. It is easier to isolate N. caninum from neural tissues of congenitally-infected full term calves (Table 2) because tissue cysts are likely to be present and tissue cysts are relatively more resistant to autolysis than tachyzoites.

Pathogenesis of abortion

Cows with N. caninum antibodies (seropositive) are more likely to abort than seronegative cows. There is a rise in antibody titers 4 to 5 months before parturition. These observations strongly suggest reactivation of latent infection. Little is known of the mechanism of reactivation. It is likely that there is parasitemia during pregnancy leading to fetal infection. However, N. caninum has never been identified in histologic sections of adult cows and there is a single report of isolation of viable N. caninum from the brain of an adult cow (Sawada et al., 2000). Although it is reasonable to speculate that pregnancy-induced immune-suppression may reactivate latent tissue cysts of N. caninum, such a mechanism has not been demonstrated for neosporosis.
Little is known at the present time concerning the pathogenesis of infection in cows following infection with a natural route (oral) and using the naturally transmitted stage of the parasite (oocyst) although oocysts are infective to cattle by the oral route. Results of experiments with dairy or beef cows inoculated parenterally with N. caninum tachyzoites indicate that the fetus can become infected and sometimes diseased by 4 weeks after inoculation of the parasite. Even at the early stage, there were lesions in placenta and the CNS and encephalitis was the predominent lesion. The extent of damage to placenta directly due to multiplication of N. caninum and by immune response is not known (Buxton et al., 2002). Gestational age may determine the outcome of infection. Fetuses infected early in pregnancy are likely to die.

Neospora caninum is a primary pathogen in cattle

Neospora caninum is one of the most efficiently transplacentally-transmitted organisms in cattle. In some herds up to 90% of cattle are infected, and most calves born congenitally-infected with N. caninum remain healthy. Therefore, there is a debate concerning whether N. caninum causes abortion in cattle or whether it is a bystander (Thurmond et al., 1999). All evidence at the present time indicates that N. caninum is a primary pathogen. However, there is a need to distinguish clinical and nonclinical N. caninum infections. In the initial reports by Anderson et al. (1991) and Barr et al. (1991), the following criteria were established to diagnose N. caninum abortion. First, the fetuses had lesions, mostly encephalitis. Second, N. caninum was found in lesions. In my opinion, identification of organisms in lesions is a good evidence for the etiology of the lesions. Additionally, abortion has been induced in experimentally-infected cattle. The percentage of fetuses that have histologically detectable N. caninum and no lesions is unknown. Therefore, detection of N. caninum DNA alone in aborted fetuses may not be enough to establish cause and effect relationship. Host factors (cytokines, hormones) that may contribute to pathogenesis of N. caninum infection have not yet been established (Buxton et al., 2002; Innes et al., 2002).

Transmission

There is no cow to cow transmission of N. caninum. In the study by Anderson et al. (1997), 25 seronegative heifers were housed with 25 seropositive heifers since birth and their progeny were evaluated for N. caninum infection. The seronegative heifers remained seronegative and gave birth to calves not infected with N. caninum. Seropositive heifers remained clinically normal but gave birth to congenitally-infected calves. Seven of these congenitally-infected calves were necropsied; all had histologic evidence of N. caninum infection and 4 were recumbent. Although most N. caninum infections in cattle are transmitted transplacentally, postnatal rates have been variable depending on the region of the country, type of test used and cut-off values used.
It is unlikely that N. caninum is transmitted venereally or by embryo transfer in cattle and embryo transfer is even recommended as a method of control to prevent vertical transmission (Baillargeon et al., 2001). These researchers conducted an important study on embryo transfer and N. caninum infection involving 87 recipient cows or heifers. Neospora caninum infection was not demonstrable in any of the 70 fetuses or calves born to seronegative cows transplanted embryos from seropositive donors whereas 5 of 6 calves resulting from embryo transfer from seronegative donors to seropositive recipients were infected with N. caninum. Landmann et al. (2002) confirmed these findings and showed that commercially used embryo transfer procedures also prevented transfer of N. caninum from seropositive cows to seronegative recipients. Additionally, preimplanted bovine embryos are resistant to N. caninum invasion (Bielanski et al., 2002).
Lactogenic transmission of N. caninum has been demonstrated experimentally in newborn calves fed colostrum spiked with tachyzoites, but there is no evidence that it occurs naturally (Davison et al., 2001); dogs fed milk spiked with N. caninum tachyzoites did not shed oocysts (Dijkstra et al., 2001).

Economic impact

There are no firm data on the economic losses due to neosporosis to cattle industry anywhere in the world but losses are estimated in millions of dollars. As many as 42% of cows may abort due to neosporosis, the economic impact will depend on the direct cost and value of fetuses lost. Indirect costs include professional help and costs associated with establishing diagnosis, rebreeding, possible loss of milk yield, and replacement costs if aborted cows are culled (Thurmond and Hietala, 1996, 1997; Hernandez et al., 2001).
In general, less is known of the causes of abortion in beef cattle than in dairy cattle because of the difficulty of finding small fetuses expelled in the first trimester. Therefore, there are no accurate assessments of Neospora-induced losses in beef cattle. Because clinical disease has not been reported in calves older than 2 months of age, there is no direct evidence of N. caninum-associated morbidity in adult cattle. However, in a sero-epidemiological study, Barling et al. (2000) found a positive association between N. caninum antibody status of the calf and weight gain and projected a $15.62 loss per calf.

Epidemiology and control

As stated earlier, N. caninum is efficiently transmitted vertically in cattle, perhaps for several generations. Therefore, culling is the only way at present to prevent this transmission from cow to heifer. Until the discovery of the resistant stage (oocyst) of N. caninum, horizontal transmission was unexplained. Evidence is accumulating that transmission by oocysts may be more prevalent than initially realized, at least in some parts of the world. Storms of abortions, abortion in recently infected cattle as evidenced by low avidity antibodies, and seroconversion in a high portion of cattle, indicate transmission of N. caninum by fecal-oral route. Postnatal transmission also occurs in herds not experiencing storms of abortions and seroepidemiological data support the role of the dog in the life cycle of N. caninum.
How dogs become infected in nature is not known. Small animals that dogs might prey or consume naturally have not been identified as a natural host for N. caninum. Consumption of aborted bovine fetuses does not appear to be an important source of N. caninum infection in dogs. The consumption of placental membranes may be a source of N. caninum infection in dogs because the parasite has been found in naturally-infected placentas and dogs fed placentas shed N. caninum oocysts. Little is known at present regarding the frequency of shedding of N. caninum oocysts by canids in nature, the resistance of the oocysts, and whether dogs shed oocysts more than once. Until more definitive hosts of N. caninum are found, dogs should not be allowed to eat aborted fetuses, fetal membranes or dead calves. Drugs that will prevent transmission of the parasite for the dam to the fetus are unknown but research is continuing in this area.
There is no proven vaccine to prevent N. caninum abortion in cattle (Innes et al., 2002). However, encouraging results have been obtained in mice vaccinated with killed parasites or their products. Vaccination of mice before pregnancy with killed N. caninum tachyzoites blocked transplacental transfer of N. caninum when mice were challenged during pregnancy demonstrated protective immunity to congenital transfer of N. caninum infection has been demonstrated in experimentally-infected cattle (Innes et al., 2001b). As mentioned earlier, protective immunity appears to develop which reduces or prevents subsequent abortion after a primary infection and resultant abortion in cattle (Anderson et al., 1995; McAllister et al., 2000). This protective immunity appears to be more effective in cows that are infected again from an exogenous source (oocysts) than in cows that relapse from an endogenous infection (Trees and Williams, 2003). Therefore, inducing protective immunity in cows that are already infected naturally is a problem.

NEOSPOROSIS IN DOGS

Neosporosis was first recognized in dogs in Norway by Bjerkås et al. (1984). Retrospectively, the earliest record of neosporosis in dogs was an outbreak in 1957 in the U.S. (Dubey et al., 1990a). Worldwide reports of clinical and subclinical infections were summarized by Dubey and Lindsay (1996) and Lindsay and Dubey (2000) and these references are not repeated here. Since then, antibodies to N. caninum were reported in 121 of 320 (37.8%) dogs from Argentina (Basso et al., 2001b), 22% of 200 dogs from New Zealand (Reichel et al., 1998), 10% of 150 dogs from Turkey (Coškun et al., 2000), 6.7% of 163 dogs from Brazil (Mineo et al., 2001), 10% of 500 pet dogs and 25% of 611 stray dogs from Brazil (Gennari et al., 2002), 6.4% of 1,058 dogs from Italy (Cringoli et al., 2002), and in 12.% of 120 urban and 26% of 81 rural dogs from Chile (Patitucci et al., 2001). Klein and Müller (2001) reported N. caninum antibodies in 4% of 50 dogs in Germany without clinical signs and 13% of 200 dogs with clinical signs. Antibodies to N. caninum were found in 21.6% of 134 dogs from cattle farms in Parana, Brazil (de Souza et al., 2002).
Three surveys compared the prevalence of N. caninum in urban and rural dogs. Sawada et al. (1998) reported N. caninum antibodies in 31% of 48 dogs from dairy farms and 7% of 198 dogs from urban areas in Japan. Wouda et al. (1999b) reported a higher prevalence in farm dogs (23.6% of 152) versus urban dogs (5.5% of 344) from the Netherlands. Basso et al. (2001b) reported higher seroprevalence in dogs from dairy farms (48% of 125) and beef farms (54.2% of 35) than in dogs from urban areas (22.2% of 160) of Argentina.
In addition to clinical infections summarized by Dubey and Lindsay (1996) and Lindsay and Dubey (2000), Boydell and Brogan (2000), Cantile and Arispici (2002) reported clinical neurologic neosporosis in dogs. Four cases of cutaneous neosporosis were recently reported, including mixed infection with Leishmania sp. in 1 dog (Tarantino et al., 2001; Perlé et al., 2001; Ordeix et al., 2002).
Barber and Trees (1998) reported an interesting seroepidemiologic study of N. caninum infections in 373 breeding dogs in U.K. Fifty (13.4%) of 373 bitches had an IFAT titer of > 1:50. Initially, approximately 50% pups born were seropositive and approximately 25% of pups born from seropositive dams developed neosporosis-like illness. Three bitches produced successive litters of N. caninum infected pups. In subsequent breeding only 3 of 118 pups from seronegative dams were seropositive. Thus, vertical transmission alone could not maintain the parasite in dogs (Barber and Trees, 1998).
The most severe cases of neosporosis occur in young, congenitally infected pups. Young dogs develop hind limb paresis that develops into a progressive paralysis. Neurologic signs are dependent on the site parasitized. The hind limbs are more severely affected than the front limbs and often in rigid hyperextention. Other dysfunctions which occur include difficulty in swallowing, paralysis of the jaw, muscle flaccidity, muscle atrophy and even heart failure. Dogs with hind limb paralysis may be alert and survive for months.
The disease may be localized or generalized and virtually all organs may be involved including the skin. Dermatitis may be severe involving enormous numbers of N. caninum. Dogs of any age can be affected. Fatal neosporosis has been reported in eight to 15-year-old dogs.
Subclinically infected bitches can transmit the parasite to their fetuses, and successive litters from the same bitch may be born infected. Whether there is breed predisposition and differential sex susceptibility to neosporosis in dogs is not known. Most described cases have been in Labrador retrievers, Boxers, Greyhounds, Golden retrievers, and Basset hounds.
Neospora caninum has been isolated several times from dogs, mostly from dogs with neuromuscular signs (Table 3). Nothing is known of the isolates of N. caninum from dogs without any clinical signs.

NEOSPOROSIS IN WATER BUFFALOES

Water buffaloes (Bubalus bubalis) are important to the economy of several countries including Brazil, India, Italy, and Vietnam. Prevalence of antibodies indicates that buffaloes in four countries were exposed to N. caninum (Table 4).
Little is known of the role of N. caninum in causing abortion in buffaloes. Guarino et al. (2000) reported lesions and Neospora-like tissue cysts in 2 of 4 fetuses aborted from 2 dairy farms in Italy; this report needs confirmation.

NEOSPOROSIS IN SHEEP

Neospora caninum was first diagnosed in a congenitally-infected lamb in England, (Dubey et al., 1990b). Historically, this was the first record of N. caninum-like infection in a ruminant (Hartley and Bridge, 1975). The lamb was born weak, partially ataxic, and died at one week of age. There was unilateral reduction of gray matter in the ventral horn and local cavitation. This case was published because congenital deformities due to toxoplasmosis had not been seen in any animal (other than humans), only tissue cysts and not tachyzoites were seen. I had known of this case even before it was published. After the discovery of the N. caninum in dogs in 1988, I contacted William Hartley and retrospectively examined tissues of this lamb and an identical case in a calf that was added as an addendum to the case in lamb (Hartley and Bridge, 1975); the calf was from Australia. Subsequently, clinical ovine neosporosis was reported from Japan. Kobayashi et al. (2001) found naturally-infected neosporosis in ewe and her twin fetus in Japan. Focal encephalitis and thick-walled N. caninum tissue cysts were seen in all three animals. Koyama et al. (2001) obtained the first isolate of N. caninum from another adult ewe.
Little is known of the seroprevalence of N. caninum in naturally exposed sheep and evidence for N. caninum as an ovine abortifacient in the field has not been found (Otter et al., 1997). In a recent survey study from U.K., only 3 of 660 ewes that had aborted had antibodies to N. caninum (Helmick et al., 2002). Pregnant sheep, however, are highly susceptible to experimental infection with N. caninum tachyzoites (Dubey and Lindsay, 1990; McAllister et al., 1996; Buxton et al., 1997b, 1998; Jolley et al., 1999; Innes et al., 2001a) and are an alternative ruminant model for bovine neosporosis. Sheep can also be infected orally with N. caninum oocysts (O'Handley et al., 2002).

NEOSPOROSIS IN GOATS

Abortion and neonatal mortality associated with N. caninum was reported in pygmy goats in the U.S. (Barr et al., 1992; Dubey et al., 1992), in a dairy goat herd in Costa Rica (Dubey et al., 1996a), and in a 3-day-old dairy goat from Brazil (Corbellini et al., 2001). Antibodies to N. caninum were found in 5 of 77 dairy goats in Costa Rica that had aborted. Little is known of the seroprevalence of N. caninum antibodies in goats. Ooi et al. (2000) did not find N. caninum antibodies in 24 goats from Taiwan.
Pygmy goats, however, are quite susceptible to experimental N. caninum infection. Goats inoculated N. caninum during pregnancy aborted N. caninum-infected fetuses (Lindsay et al., 1995).

NEOSPOROSIS IN HORSES

Neospora-like parasites have been found in tissues of two aborted foals (Dubey and Porterfield, 1990; Pronost et al., 1999), a congenitally-infected foal (Lindsay et al., 1996b) and five adult horses (Gray et al., 1996; Daft et al., 1996; Marsh et al., 1996; Hamir et al., 1998; Cheadle et al., 1999b). Marsh et al. (1998) proposed a new name, Neospora hughesi, for the parasite in the horse they reported in 1996. Three isolates of N. hughesi from adult horses have been reported (Marsh et al., 1998; Cheadle et al., 1999b; Dubey et al., 2001). Molecular and biological characteristics of these three isolates have been reported (Cheadle et al., 1999a; Walsh et al., 2000; Dubey et al., 2001; Marsh et al., 2001).
Tissue cysts of N. hughesi were smaller than N. caninum with thinner cyst walls (less than 1.0 µm thick), and bradyzoites were smaller than those of N. caninum (Marsh et al., 1998). It is, however, not clear at the present time whether N. hughesi is the sole species of Neospora that infects horses. Thick walled tissue cysts, characteristics of N. caninum were reported from a horse from California (Daft et al., 1996) and a congenitally infected foal from Wisconsin (Lindsay et al., 1996b).
Seroprevalence of Neospora infections in horses is summarized in Table 5. In two surveys or horses in France and the U.S. the seroprevalence by NAT was 23%.

NEOSPORA INFECTIONS IN HUMANS

Because two rhesus monkeys (Macaca mulata) have been successfully infected with N. caninum (Barr et al., 1994), there is a concern about the zoonotic potential of N. caninum. However, at present there is no evidence that N. caninum successfully infects humans. Graham et al. (1999) did not find N. caninum antibodies in 1:160 dilution of sera from 199 blood donors and 48 agricultural workers in Northern Ireland. Petersen et al. (1999) did not find antibodies to N. caninum in 76 women with history of abortion using ELISA, immunoblotting, and IFAT. Low level IFAT (1:100) antibodies were reported by Tranas et al. (1999) in 69 (6.7%) of 1,029 sera from blood donors in California, however, all sera were negative at 1:200 dilution. Nam et al. (1998) reported antibodies to N. caninum in human sera using the immunoblots; however, these sera were negative by NAT. Trees and Williams. (2000) found low (IFAT < 1:200) in 2 of 500 (400 farm workers and 100 women with recurrent abortions) people in England. In conclusion, there is no evidence that N. caninum infection is zoonotic.

NEOSPOROSIS IN WILDLIFE

Neosporosis was diagnosed at necropsy in two black-tailed deer (Odocoileus hemionus columbianus) found dead in the wild in California (Woods et al., 1994), in a captive deer in zoos in France (Dubey et al., 1996b, and Germany (Peters et al., 2001b. Neospora caninum tissue cysts were found in the brain of a full term stillborn deer (Cervus eldi siamensis) in a Paris Zoo (Dubey et al., 1996b. Peters et al. (2001b) reported antibodies to N. caninum in fetal fluid and N. caninum DNA by PCR in the brain, heart, lung, liver and spleen of 2 full term twin calves of antelope (Tragelaphus imberberis) in a zoo in Hannover, Germany.
Neosporosis was reported in a rhinoceros (Ceratotherium simum) calf (Williams et al., 2002). The animal died suddenly, considered to be due to myocarditis. Rhinoceroses are related to equids, all belonging to the order Perissodactyla.
Finding of antibodies in 40% of wild deer (Table 9) indicates there may be a sylvatic cycle of N. caninum. A large percentage of these deer had high titered (> 1:1,600) N. caninum antibodies and the prevalence did not increase with age indicating that congenital transmission (Dubey et al., 1999a). Similarly, red foxes in Belgium had a high seroprevalence of N. caninum. Schares et al. (2001) presented evidence of congenital infection of N. caninum in foxes.

REFERENCES

1. Alméria S, Ferrer D, Pabón M, Castell J, Maas S. Red foxes (Vulpes vulpes) are a natural intermediate host of Neospora caninum. Vet Parasitol 2002;107:287-294. PMID: 12163240.
crossref
2. Anderson ML, Blanchard PC, Barr BC, Dubey JP, Hoffmann RL, Conrad PA. Neospora-like protozoan infection as a major cause of abortion in California dairy cattle. J Am Vet Med Assoc 1991;198:241-244. PMID: 2004983.

3. Anderson ML, Palmer CW, Thurmond MC, et al. Evaluation of abortions in cattle attributable to neosporosis in selected dairy herds in California. J Am Vet Med Assoc 1995;207:1206-1210. PMID: 7559072.

4. Anderson ML, Reynolds JP, Rowe JD, et al. Evidence of vertical transmission of Neospora sp infection in dairy cattle. J Am Vet Med Assoc 1997;210:1169-1172. PMID: 9108925.

5. Anderson ML, Andrianarivo AG, Conrad PA. Neosporosis in cattle. Anim Reprod Sci 2000;60-61:417-431. PMID: 10844212.
crossref
6. Baillargeon P, Fecteau G, Pare J, Lamothe P, Sauve R. Evaluation of the embryo transfer procedure proposed by the International Embryo Transfer Society as a method of controlling vertical transmission of Neospora caninum in cattle. J Am Vet Med Assoc 2001;218:1803-1806. PMID: 11394835.
crossref
7. Barber JS, Holmdahl OJM, Owen MR, Guy F, Uggla A, Trees AJ. Characterization of the first European isolate of Neospora caninum (Dubey, Carpenter, Speer, Topper and Uggla). Parasitology 1995;111:563-568. PMID: 8559588.
crossref
8. Barber JS, Gasser RB, Ellis J, Reichel MP, McMillan D, Trees AJ. Prevalence of antibodies to Neospora caninum in different canid populations. J Parasitol 1997;83:1056-1058. PMID: 9406778.
crossref
9. Barber JS, Trees AJ. Naturally occurring vertical transmission of Neospora caninum in dogs. Int J Parasitol 1998;28:57-64. PMID: 9504335.
crossref
10. Barling KS, McNeill JW, Thompson JA, et al. Association of serologic status for Neospora caninum with postweaning weight gain and carcass measurements in beef calves. J Am Vet Med Assoc 2000;217:1356-1360. PMID: 11061390.
crossref
11. Barr BC, Anderson ML, Dubey JP, Conrad PA. Neospora-like protozoal infections associated with bovine abortions. Vet Pathol 1991;28:110-116. PMID: 2063512.
crossref
12. Barr BC, Anderson ML, Woods LW, Dubey JP, Conrad PA. Neospora-like protozoal infections associated with abortion in goats. J Vet Diagn Invest 1992;4:365-367. PMID: 1515507.
crossref
13. Barr BC, Conrad PA, Breitmeyer R, et al. Congenital Neospora infection in calves born from cows that had previously aborted Neospora-infected fetuses: four cases (1990-1992). J Am Vet Med Assoc 1993;202:113-117. PMID: 8420896.

14. Barr BC, Conrad PA, Sverlow KW, Tarantal AF, Hendrickx AG. Experimental fetal and transplacental Neospora infection in the nonhuman primate. Laboratory Investigation 1994;71:236-242. PMID: 8078303.

15. Basso W, Venturini L, Venturini MC, et al. First isolation of Neospora caninum from the feces of a naturally infected dog. J Parasitol 2001a;87:612-618. PMID: 11426726.
crossref
16. Basso W, Venturini L, Venturini MC, et al. Prevalence of Neospora caninum infection in dogs from beef-cattle farms, dairy farms, and from urban areas of Argentina. J Parasitol 2001b;87:906-907. PMID: 11534656.
crossref
17. Bielanski A, Robinson J, Phipps-Todd B. Effect of Neospora caninum on in vitro development of preimplantation stage bovine embryos and adherence to the zona pellucida. Vet Rec 2002;150:316-318. PMID: 11913589.
crossref
18. Bjerkås I, Mohn SF, Presthus J. Unidentified cyst-forming sporozoon causing encephalomyelitis and myositis in dogs. Z Parasitenk 1984;70:271-274. PMID: 6426185.
crossref
19. Boulton JG, Gill PA, Cook RW, Fraser GC, Harper PAW, Dubey JP. Bovine Neospora abortion in north-eastern New South Wales. Aust Vet J 1995;72:119-120. PMID: 7611986.
crossref
20. Boydell P, Brogan N. Horner's syndrome associated with Neospora infection. J Small Anim Pract 2000;41:571-572. PMID: 11138858.
crossref
21. Buxton D, Maley SW, Pastoret PP, Brochier B, Innes EA. Examination of red foxes (Vulpes vulpes) from Belgium for antibody to Neospora caninum and Toxoplasma gondii. Vet Rec 1997a;141:308-309. PMID: 9330477.
crossref
22. Buxton D, Maley SW, Thomson KM, Trees AJ, Innes EA. Experimental infection of non-pregnant and pregnant sheep with Neospora caninum. J Comp Pathol 1997b;117:1-16. PMID: 9263840.
crossref
23. Buxton D, Maley SW, Wright S, Thomson KM, Rae AG, Innes EA. The pathogenesis of experimental neosporosis in pregnant sheep. J Comp Pathol 1998;118:267-279. PMID: 9651804.
crossref
24. Buxton D, McAllister M, Dubey JP. The comparative pathogenesis of neosporosis. Trends Parasitol 2002;18:546-552. PMID: 12482540.
crossref
25. Canada N, Meireles CS, Rocha A, et al. First Portuguese isolate of Neospora caninum from an aborted fetus from a dairy herd with endemic neosporosis. Vet Parasitol 2002a;110:11-15. PMID: 12446085.
crossref
26. Canada N, Meireles CS, Rocha A, Correia da Costa JM, Erickson MW, Dubey JP. Isolation of viable Toxoplasma gondii from naturally-infected aborted bovine fetuses. J Parasitol 2002b;88:1247-1248. PMID: 12537120.
crossref
27. Cantile C, Arispici M. Necrotizing cerebellitis due to Neospora caninum infection in an old dog. J Vet Med 2002;49:47-50.
crossref
28. Cheadle MA, Spencer JA, Blackburn BL. Seroprevalences of Neospora caninum and Toxoplasma gondii in nondomestic felids from southern Africa. J Zoo Wildlife Med 1999a;30:248-251.

29. Cheadle MA, Lindsay DS, Rowe S, et al. Prevalence of antibodies to Neospora caninum in horses from Alabama and characterisation of an isolate recovered from a naturally infected horse. Int J Parasitol 1999b;29:1537-1543. PMID: 10608440.
crossref
30. Conrad PA, Barr BC, Sverlow KW, et al. In vitro isolation and characterization of a Neospora sp. from aborted bovine foetuses. Parasitology 1993;106:239-249. PMID: 8488061.
crossref
31. Corbellini LG, Colodel EM, Driemeier D. Granulomatous encephalitis in a neurologically impaired goat kid associated with degeneration of Neospora caninum tissue cysts. J Vet Diagn Invest 2001;13:416-419. PMID: 11580064.
crossref
32. Corbellini LG, Driemeier D, Cruz CFE, Gondim LFP, Wald V. Neosporosis as a cause of abortion in dairy cattle in Rio Grande do Sul, southern Brazil. Vet Parasitol 2002;103:195-202. PMID: 11750112.
crossref
33. Cringoli G, Rinaldi E, Capuano F, Baldi L, Veneziano V, Capelli G. Serological survey of Neospora caninum and Leishmania infantum co-infection in dogs. Vet Parasitol 2002;106:307-313. PMID: 12079736.
crossref
34. Cuddon P, Lin DS, Bowman DD, et al. Neospora caninum infection in English springer spaniel littermates: Diagnostic evaluation and organism isolation. J Vet Intern Med 1992;6:325-332. PMID: 1484374.
crossref
35. Çoškun SZ, Aydyn L, Bauer C. Seroprevalence of Neospora caninum infection in domestic dogs in Turkey. Vet Rec 2000;146:649. PMID: 10872789.
crossref
36. Daft BM, Barr BC, Collins N, Sverlow K. Neospora encephalomyelitis and polyradiculoneuritis in an aged mare with Cushing's disease. Equine Vet J 1996;28:240-243.

37. Davison HC, Guy F, Trees AJ, et al. In vitro isolation of Neospora caninum from a stillborn calf in the UK. Res Vet Sci 1999;67:103-105. PMID: 10425249.
crossref
38. Davison HC, Guy CS, McGarry JW, Guy F, Williams DJL, Trees AJ. Experimental studies on the transmission of Neospora caninum between cattle. Res Vet Sci 2001;70:163-168. PMID: 11356096.
crossref
39. de Souza SLP, Guimares JS, Ferreira F, Dubey JP, Gennari SM. Prevalence of Neospora caninum antibodies in dogs from dairy cattle farms in Parana, Brazil. J Parasitol 2002;88:408-409. PMID: 12054023.
crossref
40. Dijkstra T, Eysker M, Schares G, Conraths FJ, Wouda W, Barkema HW. Dogs shed Neospora caninum oocysts after ingestion of naturally infected bovine placenta but not after ingestion of colostrum spiked with Neospora caninum tachyzoites. Int J Parasitol 2001;31:747-752. PMID: 11403764.
crossref
41. Dijkstra T. Horizontal and vertical transmission of Neospora caninum. 2002, the Netherlands. Univ. Utrecht. pp 1-140 PhD Thesis.

42. Dubey JP, Carpenter JL, Speer CA, Topper MJ, Uggla A. Newly recognized fatal protozoan disease of dogs. J Am Vet Med Assoc 1988a;192:1269-1285. PMID: 3391851.

43. Dubey JP, Hattel AL, Lindsay DS, Topper MJ. Neonatal Neospora caninum infection in dogs: Isolation of the causative agent and experimental transmission. J Am Vet MEd Assoc 1988b;193:1259-1263. PMID: 3144521.

44. Dubey JP, Lindsay DS. Neospora caninum induced abortion in sheep. J Vet Diagn Invest 1990;2:230-233. PMID: 2094452.
crossref
45. Dubey JP, Porterfield ML. Neospora caninum (Apicomplexa) in an aborted equine fetus. J Parasitol 1990;76:732-734. PMID: 2213418.
crossref
46. Dubey JP, Koestner A, Piper RC. Repeated transplacental transmission of Neospora caninum in dogs. J Am Vet Med Assoc 1990a;197:857-860. PMID: 2228766.

47. Dubey JP, Hartley WJ, Lindsay DS, Topper MJ. Fatal congenital Neospora caninum infection in a lamb. J Parasitol 1990b;76:127-130. PMID: 2299518.
crossref
48. Dubey JP, Acland HM, Hamir AN. Neospora caninum (Apicomplexa) in a stillborn goat. J Parasitol 1992;78:532-534. PMID: 1597802.
crossref
49. Dubey JP, Lindsay DS. A review of Neospora caninum and neosporosis. Vet Parasitol 1996;67:1-59. PMID: 9011014.
crossref
50. Dubey JP, Morales JA, Villalobos P, Lindsay DS, Blagburn BL, Topper MJ. Neosporosis-associated abortion in a dairy goat. J Am Vet Med Assoc 1996a;208:263-265. PMID: 8567387.

51. Dubey JP, Rigoulet J, Lagourette P, George C, Longeart L, LeNet JL. Fatal transplacental neosporosis in a deer (Cervus eldi siamensis). J Parasitol 1996b;82:338-339. PMID: 8604111.
crossref
52. Dubey JP, Dorough KR, Jenkins MC, et al. Canine neosporosis: clinical signs, diagnosis, treatment and isolation of Neospora caninum in mice and cell culture. Int J Parasitol 1998a;28:1293-1304. PMID: 9762578.
crossref
53. Dubey JP, Romand S, Hilali M, Kwok OCH, Thulliez P. Seroprevalence of antibodies to Neospora caninum and Toxoplasma gondii in water buffaloes (Bubalus bubalis) from Egypt. Int J Parasitol 1998b;28:527-529. PMID: 9559371.
crossref
54. Dubey JP, Hollis K, Romand S, et al. High prevalence of antibodies to Neospora caninum in white-tailed deer (Odocoileus virginianus). Int J Parasitol 1999a;29:1709-1711. PMID: 10608458.
crossref
55. Dubey JP, Romand S, Thulliez P, Kwok OCH, Shen SK, Gamble HR. Prevalance of antibodies to Neospora caninum in horses in North America. J Parasitol 1999b;85:968-969. PMID: 10577738.
crossref
56. Dubey JP, Kerber CE, Granstrom DE. Serologic prevalence of Sarcocystis neurona, Toxoplasma gondii, and Neospora caninum in horses in Brazil. J Am Vet Med Assoc 1999c;215:970-972. PMID: 10511862.

57. Dubey JP, Venturini MC, Venturini L, McKinney J, Pecoraro M. Prevalence of antibodies to Sarcocystis neurona, Toxoplasma gondii, and Neospora caninum in horses from Argentina. Vet Parasitol 1999d;86:59-62. PMID: 10489203.
crossref
58. Dubey JP. Recent advances in Neospora and neosporosis. Vet Parasitol 1999;84:349-367. PMID: 10456423.
crossref
59. Dubey JP, Lindsay DS. Gerbils (Meriones unguiculatus) are highly susceptible to oral infection with Neospora caninum oocyst. Parasitol Res 2000;86:165-168. PMID: 10685849.
crossref
60. Dubey JP, Liddell S, Mattson D, Speer CA, Howe DK, Jenkins MC. Characterization of the Oregon isolate of Neospora hughesi from a horse. J Parasitol 2001;87:345-353. PMID: 11318565.
crossref
61. Dubey JP, Barr BC, Barta JR, et al. Redescription of Neospora caninum and its differentiation from related coccidia. Int J Parasitol 2002;32:929-946. PMID: 12076623.
crossref
62. Dubey JP. Neosporosis in cattle. J Parasitol 2003;89(Supplement):in press.
crossref
63. Fioretti DP, Rosignoli L, Ricci G, Moretti A, Pasquali P, Polidori GA. Neospora caninum infection in a clinically healthy calf: parasitological study and serological follow-up. J Vet Med B 2000;47:47-53.
crossref
64. Fujii TU, Kasai N, Nishi SM, Dubey JP, Gennari SM. Seroprevalence of Neospora caninum in female water buffaloes (Bubalus bubalis) from the southeastern region of Brazil. Vet Parasitol 2001;99:331-334. PMID: 11511420.
crossref
65. Gennari SM, Yai LEO, D'Auria SNR, et al. Occurrence of Neospora caninum antibodies in sera from dogs of the city of São Paulo, Brazil. Vet Parasitol 2002;106:177-179. PMID: 12031819.
crossref
66. Gondim LFP, Pinheiro AM, Santos POM, et al. Isolation of Neospora caninum from the brain of a naturally infected dog and production of encysted bradyzoites in gerbils. Vet Parasitol 2001;101:1-7. PMID: 11587828.
crossref
67. Gondim LFP, Gao L, McAllister MM. Improved production of Neospora caninum oocysts, cyclical oral transmission between dogs and cattle, and in vitro isolation from oocysts. J Parasitol 2002;88:1159-1163. PMID: 12537111.
crossref
68. Graham DA, Calvert V, Whyte M, Marks J. Absence of serological evidence for human Neospora caninum infection. Vet Rec 1999;144:672-673. PMID: 10404607.
crossref
69. Gray ML, Harmon BG, Sales L, Dubey JP. Visceral neosporosis in a 10-year-old horse. J Vet Diagn Invest 1996;8:130-133. PMID: 9026072.
crossref
70. Guarino A, Fusco G, Savini G, Di Francesco G, Cringoli G. Neosporosis in water buffalo (Bubalus bubalis) in southern Italy. Vet Parasitol 2000;91:15-21. PMID: 10889356.
crossref
71. Gupta GD, Lakritz J, Kim JH, Kim DY, Kim JK, Marsh AE. Seroprevalence of Neospora, Toxoplasma gondii, and Sarcocystis neurona antibodies in horses from Jeju island, South Korea. Vet Parasitol 2002;106:193-201. PMID: 12062508.
crossref
72. Hamir AN, Tornquist SJ, Gerros TC, Topper MJ, Dubey JP. Neospora caninum - associated equine protozoal myeloencephalitis. Vet Parasitol 1998;79:269-274. PMID: 9831950.
crossref
73. Hartley WJ, Bridge PS. A case of suspected congenital Toxoplasma encephalomyelitis in a lamb associated with a spinal cord anomaly. Br Vet J 1975;131:380-384. PMID: 1148804.

74. Hay WH, Shell LG, Lindsay DS, Dubey JP. Diagnosis and treatment of Neospora caninum infection in a dog. J Am Vet Med Assoc 1990;197:87-89. PMID: 2370226.

75. Helmick B, Otter A, McGarry J, Buxton D. Serological investigation of aborted sheep and pigs for infection by Neospora caninum. Res Vet Sci 2002;73:187. PMID: 12204640.
crossref
76. Hernandez J, Risco C, Donovan A. Association between exposure to Neospora caninum and milk production in dairy cows. J Am Vet Med Assoc 2001;219:632-635. PMID: 11549092.
crossref
77. Hill DE, Liddell S, Jenkins MC, Dubey JP. Specific detection of Neospora caninum oocyst in fecal samples from experimentally-infected dogs using the polymerase chain reaction. J Parasitol 2001;87:395-398. PMID: 11318571.
crossref
78. Huong LTT, Ljungstrom BL, Uggla A, Bjorkman C. Prevalence of antibodies to Neospora caninum and Toxoplasma gondii in cattle and water buffaloes in southern Vietnam. Vet Parasitol 1998;75:53-57. PMID: 9566094.
crossref
79. Innes EA, Lunden A, Esteban I, et al. A previous infection with Toxoplasma gondii does not protect against a challenge with Neospora caninum in pregnant sheep. Parasite Immunol 2001a;23:121-132. PMID: 11240903.
crossref
80. Innes EA, Wright SE, Maley S, et al. Protection against vertical transmission in bovine neosporosis. Int J Parasitol 2001b;31:1523-1534. PMID: 11595240.
crossref
81. Innes EA, Andrianarivo AG, Björkman C, Williams DJL, Conrad PA. Immune responses to Neospora caninum and prospects for vaccination. Trends Parasitol 2002;18:497-504. PMID: 12473366.
crossref
82. Jakubek EB, Bröjer C, Regnersen C, Uggla A, Schares G, Bjorkman C. Seroprevalences of Toxoplasma gondii and Neospora caninum in Swedish red foxes (Vulpes vulpes). Vet Parasitol 2001;102:167-172. PMID: 11705663.
crossref
83. Jenkins M, Baszler T, Bjorkman C, Schares G, Williams D. Diagnosis and seroepidemiology of Neospora caninum-associated bovine abortion. Int J Parasitol 2002;32:631-636. PMID: 11943234.
crossref
84. Jolley WR, McAllister MM, McGuire AM, Wills RA. Repetitive abortion in Neospora-infected ewes. Vet Parasitol 1999;82:251-257. PMID: 10348105.
crossref
85. Kim JH, Sohn HJ, Hwang WS, et al. In vitro isolation and characterization of bovine Neospora caninum in Korea. Vet Parasitol 2000;90:147-154. PMID: 10828521.
crossref
86. Klein BU, Muller E. Seroprävalenz von antikörpern gegen Neospora caninum bei Hunden mit und ohne klinischem Neosporoseverdacht in Deutschland. Der praktische Tierarzt 2001;82:437-440.

87. Kobayashi Y, Yamada M, Omata Y, et al. Naturally-occurring Neospora caninum infection in an adult sheep and her twin fetuses. J Parasitol 2001;87:434-436. PMID: 11318580.
crossref
88. Koyama T, Kobayashi Y, Omata Y, et al. Isolation of Neospora caninum from the brain of a pregnant sheep. J Parasitol 2001;87:1486-1488. PMID: 11780846.
crossref
89. Landmann JK, Jillella D, O'Donoghue PJ, McGowan MR. Confirmation of the prevention of vertical transmission of Neospora caninum in cattle by the use of embryo transfer. Aust Vet J 2002;80:502-503. PMID: 12224621.
crossref
90. Lindsay DS, Rippey NS, Powe TA, Sartin EA, Dubey JP, Blagburn BL. Abortions, fetal death, and stillbirths in pregnant pygmy goats inoculated with tachyzoites of Neospora caninum. Am J Vet Res 1995;56:1176-1180. PMID: 7486395.

91. Lindsay DS, Kelly EJ, McKown R, et al. Prevalence of Neospora caninum and Toxoplasma gondii antibodies in coyotes (Canis latrans) and experimental infections of coyotes with Neospora caninum. J Parasitol 1996a;82:657-659. PMID: 8691381.
crossref
92. Lindsay DS, Steinberg H, Dubielzig RR, et al. Central nervous system neosporosis in a foal. J Vet Diagn Invest 1996b;8:507-510. PMID: 8953546.
crossref
93. Lindsay DS, Dubey JP, Duncan RB. Confirmation that the dog is a definitive host for Neospora caninum. Vet Parasitol 1999a;82:327-333. PMID: 10384909.
crossref
94. Lindsay DS, Upton SJ, Dubey JP. A structural study of the Neospora caninum oocyst. Int J Parasitol 1999b;29:1521-1523. PMID: 10608437.
crossref
95. Lindsay DS, Dubey JP. Canine neosporosis. J Vet Parasitol 2000;14:1-11.

96. Lindsay DS, Ritter DM, Brake D. Oocyst excretion in dogs fed mouse brains containing tissue cysts of a cloned line of Neospora caninum. J Parasitol 2001a;87:909-911. PMID: 11534658.
crossref
97. Lindsay DS, Spencer J, Rupprecht CE, Blagburn BL. Prevalence of agglutinating antibodies to Neospora caninum in raccoons, Procyon lotor. J Parasitol 2001b;87:1197-1198. PMID: 11695399.
crossref
98. Lindsay DS, Weston JL, Little SE. Prevalence of antibodies to Neospora caninum and Toxoplasma gondii in gray foxes (Urocyon cinereoargenteus) from South Carolina. Vet Parasitol 2001c;97:159-164. PMID: 11358632.
crossref
99. Lindsay DS, Little SE, Davidson WR. Prevalence of antibodies to Neospora caninum in white-tailed deer, Odocoileus virginianus, from the Southeastern United States. J Parasitol 2002;88:415-417. PMID: 12054027.
crossref
100. Magnino S, Vigo PG, Fabbi M. Isolation of a bovine Neospora from a newborn calf in Italy. Vet Rec 1999;144:456. PMID: 10343382.

101. Marsh AE, Barr BC, Madigan J, Lakritz J, Nordhausen R, Conrad PA. Neosporosis as a cause of equine protozoal myeloencephalitis. J Am Vet Med Assoc 1996;209:1907-1913. PMID: 8944807.

102. Marsh AE, Barr BC, Packham AE, Conrad PA. Description of a new Neospora species (Protozoa: Apicomplexa: Sarcocystidae). J Parasitol 1998;84:983-991. PMID: 9794642.
crossref
103. Marsh AE, Johnson PJ, Ramos-Vara J, Johnson GC. Characterization of a Sarcocystis neurona isolate from a Missouri horse with equine protozoal myeloencephalitis. Vet Parasitol 2001;95:143-154. PMID: 11223195.
crossref
104. McAllister MM, McGuire AM, Jolley WR, Lindsay DS, Trees AJ, Stobart RH. Experimental neosporosis in pregnant ewes and their offspring. Vet Parasitol 1996;33:647-655.
crossref
105. McAllister MM, Dubey JP, Lindsay DS, Jolley WR, Wills RA, McGuire AM. Dogs are definitive hosts of Neospora caninum. Int J Parasitol 1998;28:1473-1478. PMID: 9770635.
crossref
106. McAllister MM, Bjorkman C, Anderson-Sprecher R, Rogers DG. Evidence of point-source exposure to Neospora caninum and protective immunity in a herd of beef cows. J Am Vet Med Assoc 2000;217:881-887. PMID: 10997162.
crossref
107. McDole MG, Gay JM. Seroprevalence of antibodies against Neospora caninum in diagnostic equine serum samples and their possible association with fetal loss. Vet Parasitol 2002;105:257-260. PMID: 11934465.
crossref
108. Mineo TWP, Silva DAO, Costa GHN, et al. Detection of IgG antibodies to Neospora caninum and Toxoplasma gondii in dogs examined in veterinary hospital from Brazil. Vet Parasitol 2001;98:239-245. PMID: 11423182.
crossref
109. Miller CMD, Quinn HE, Windsor PA, Ellis JT. Characterization of the first Australian isolate of Neospora caninum from cattle. Aust Vet J 2002;80:620-625. PMID: 12465814.
crossref
110. Moore DP, Campero CM, Odeon AC, et al. Seroepidemiology of beef and dairy herds and fetal study of Neospora caninum in Argentina. Vet Parasitol 2002;107:303-316. PMID: 12163242.
crossref
111. Morales E, Trigo FJ, Ibarra F, Puente E, Santacruz M. Neosporosis in Mexican dairy herds: Lesions and immunohistochemical detection of Neospora caninum in fetuses. J Comp Pathol 2001;125:58-63. PMID: 11437517.
crossref
112. Nam HW, Kang SW, Choi WY. Antibody reaction of human anti-Toxoplasma gondii positive and negative sera with Neospora caninum antigens. Korean J Parasitol 1998;36:269-275. PMID: 9868893.
crossref
113. O'Handley R, Liddell S, Parker C, Jenkins M, Dubey JP. Experimental infection of sheep with Neospora caninum oocysts. J Parasitol 2002;88:1120-1123. PMID: 12537104.
crossref
114. Ooi HK, Huang CC, Yang CH, Lee SH. Serological survey and first finding of Neospora caninum in Taiwan, and the detection of its antibodies in various body fluids of cattle. Vet Parasitol 2000;90:47-55. PMID: 10828511.
crossref
115. Ordeix L, Lloret A, Fondevila D, Dubey JP, Ferrer L, Fondati A. Cutaneous neosporosis during treatment of pemphigus foliaceus in a dog. J Am Anim Hosp Assoc 2002;38:415-419. PMID: 12220024.
crossref
116. Otter A, Wilson BW, Scholes SFE, Jeffrey M, Helmick B, Trees AJ. Results of a survey to determine whether Neospora is a significant cause of ovine abortion in England and Wales. Vet Rec 1997;140:175-177. PMID: 9055394.
crossref
117. Paré J, Fecteau G, Fortin M, Marsolais G. Seroepidemiologic study of Neospora caninum in dairy herds. J Am Vet Med Assoc 1998;213:1595-1598. PMID: 9838960.

118. Patitucci AN, Phil M, Pérez MJ, Rozas MA, Israel KF. Neosporosis canina: presencia de anticuerpos séricos en poblaciones caninas rurales y urbanas de Chile. Arch Med Vet 2001;33:227-232.
crossref
119. Perlé KMD, Del Piero F, Carr RF, Harris C, Stromberg PC. Cutaneous neosporosis in two adult dogs on chronic immunosuppressive therapy. J Vet Diagn Invest 2001;13:252-255. PMID: 11482605.
crossref
120. Peters M, Wagner F, Schares G. Canine neosporosis: clinical and pathological findings and first isolation of Neospora caninum in Germany. Parasitol Res 2000;86:1-7. PMID: 10669128.
crossref
121. Peters M, Lutkefels E, Heckeroth AR, Schares G. Immunohistochemical and ultrastructural evidence for Neospora caninum tissue cysts in skeletal muscles of naturally infected dogs and cattle. Int J Parasitol 2001a;31:1144-1148. PMID: 11429181.
crossref
122. Peters M, Wohlsein P, Knieriem A, Schares G. Neospora caninum infection associated with stillbirths in captive antelopes (Tragelaphus imberbis). Vet Parasitol 2001b;97:153-157. PMID: 11358631.
crossref
123. Petersen E, Lebech M, Jensen L, et al. Neospora caninum infection and repeated abortions in humans. Emerging Infectious Diseases 1999;5:278-280. PMID: 10221883.
crossref
124. Pipano E, Shkap V, Fish L, Savitsky I, Perl S, Orgad U. Susceptibility of Psammomys obesus and Meriones tristrami to tachyzoites of Neospora caninum. J Parasitol 2002;88:314-319. PMID: 12054004.
crossref
125. Pitel PH, Pronost S, Romand S, Thulliez P, Fortier G, Ballet JJ. Prevalence of antibodies to Neospora caninum in horses in France. Equine Vet J 2001;33:205-207. PMID: 11266072.
crossref
126. Pronost S, Pitel PH, Romand S, Thulliez P, Collobert C, Fortier G. Neospora caninum: premiére mise en évidence in France sur un avorton équin, analyse et perspectives. Prat Vét Equine 1999;31:31-34.

127. Reichel MP, Thorton RN, Morgan PL, Mills RJM, Schares G. Neosporosis in a pup. N Z Vet J 1998;46:106-110. PMID: 16032029.
crossref
128. Sager H, Fischer I, Furrer K, et al. A Swiss case-control study to assess Neospora caninum-associated bovine abortions by PCR, histopathology and serology. Vet Parasitol 2001;102:1-15. PMID: 11705647.
crossref
129. Sawada M, Park CH, Kondo H, et al. Serological survey of antibody to Neospora caninum in Japanese dogs. J Vet Med Sci 1998;60:853-854. PMID: 9713815.
crossref
130. Sawada M, Kondo H, Tomioka Y, et al. Isolation of Neospora caninum from the brain of a naturally infected adult dairy cow. Vet Parasitol 2000;90:247-252. PMID: 10842005.
crossref
131. Schares G, Heydorn AO, Cuppers A, Conraths FJ, Mehlhorn H. Hammondia heydorni-like oocysts shed by a naturally infected dog and Neospora caninum NC-1 cannot be distinguished. Parasitol Res 2001;87:808-816. PMID: 11688886.
crossref
132. Simpson VR, Monies RJ, Riley P, Cromey DS. Foxes and neosporosis. Vet Rec 1997;141:503. PMID: 9402726.
crossref
133. Šlapeta JR, Modry D, Kyselova I, Horejs R, Lukes J, Koudela B. Dog shedding oocysts of Neospora caninum: PCR diagnosis and molecular phylogenic approach. Vet Parasitol 2002;109:157-167. PMID: 12423929.
crossref
134. Söndgen P, Peters M, Bärwald A, et al. Bovine neosporosis: immunoblot improves foetal serology. Vet Parasitol 2001;102:279-290. PMID: 11731071.
crossref
135. Stenlund S, Bjorkman C, Holmdahl OJM, Kindahl H, Uggla A. Characterisation of a Swedish bovine isolate of Neospora caninum. Parasitol Res 1997;83:214-219. PMID: 9089715.
crossref
136. Tarantino C, Rossi G, Kramer LH, Perrucci S, Cringoli G, Macchioni G. Leishmania infantum and Neospora caninum simultaneous skin infection in a young dog in Italy. Vet Parasitol 2001;102:77-83. PMID: 11705654.
crossref
137. Thurmond MC, Anderson ML, Blanchard PC. Secular and seasonal trends of Neospora abortion in California dairy cows. J Parasitol 1995;81:364-367. PMID: 7776121.
crossref
138. Thurmond MC, Hietala SK. Culling associated with Neospora caninum infection in dairy cows. Am J Vet Res 1996;57:1559-1562. PMID: 8915429.

139. Thurmond MC, Hietala SK. Effect of Neospora caninum infection on milk production in first-lactation dairy cows. J Am Vet Med Assoc 1997;210:672-674. PMID: 9054999.

140. Thurmond MC, Hietala SK. Neospora caninum infection and abortion in cattle. 1999, 4. pp 425-431.

141. Tranas J, Heinzen RA, Weiss LM, McAllister MM. Serological evidence of human infection with the protozoan Neospora caninum. Clin Diagn Lab Immunol 1999;6:765-767. PMID: 10473533.

142. Trees AJ, Williams DJL. Neosporosis in the United Kingdom. Int J Parasitol 2000;30:891-893.

143. Trees AJ, Williams DJL. Vaccination against bovine neosporosis - the challenge is the challenge. J Parasitol 2003;89(Supplement):in press.

144. Vardeleon D, Marsh AE, Thorne JG, Loch W, Young R, Johnson PJ. Prevalence of Neospora hughesi and Sarcocystis neurona antibodies in horses from various geographical locations. Vet Parasitol 2001;95:273-282. PMID: 11223207.
crossref
145. Walsh CP, Duncan RB, Zajac AM, Blagburn BL, Lindsay DS. Neospora hughesi: experimental infections in mice, gerbils, and dogs. Vet Parasitol 2000;92:119-128. PMID: 10946135.
crossref
146. Williams JH, Espie I, van Wilpe E, Matthee A. Neosporosis in a white rhinoceros (Ceratotherium simum) calf. Tydskr S Afr Vet Ver 2002;73:38-43.

147. Wolfe A, Hogan S, Maguire D, et al. Red foxes (Vulpes vulpes) in Ireland as hosts for parasites of potential zoonotic and veterinary significance. Vet Rec 2001;149:759-763. PMID: 11808662.
crossref
148. Woods LW, Anderson ML, Swift PK, Sverlow KW. Systemic neosporosis in a California black-tailed deer (Odocoileus hemionus columbianus). J Vet Diagn Invest 1994;6:508-510. PMID: 7858040.
crossref
149. Wouda W, Moen AR, Visser IJR, van Knapen F. Bovine fetal neosporosis: a comparison of epizootic and sporadic abortion cases and different age classes with regard to lesion severity and immunohistochemical identification of organisms in brain, heart, and liver. J Vet Diagn Invest 1997;9:180-185. PMID: 9211238.
crossref
150. Wouda W. Neospora abortion in cattle, aspects of diagnosis and epidemiology. 1998, the Netherlands. Univ. Utrecht. pp 1-176 PhD Thesis.

151. Wouda W, Bartels CJM, Moen AR. Characteristics of Neospora caninum-associated abortion storms in dairy herds in the Netherlands (1995-1997). Theriogenology 1999a;52:233-245. PMID: 10734391.
crossref
152. Wouda W, Dijkstra T, Kramer AMH, van Maanen C, Brinkhof JMA. Seroepidemiological evidence for a relationship between Neospora caninum infections in dogs and cattle. Int J Parasitol 1999b;29:1677-1682. PMID: 10608454.
crossref
153. Yamane I, Kokuho T, Shimura K, et al. In vitro isolation and characterisation of a bovine Neospora species in Japan. Res Vet Sci 1997;63:77-80. PMID: 9368961.
crossref
Fig. 1
Life cycle of Neospora caninum.
kjp-41-1-g001
Fig. 2
Neospora caninum stages in dogs. Bar = 20 µm and applies to all figures. (A) Tachyzoites in an impression smear of lung. Giemsa stain. Note individual organisms (arrowheads) and those dividing into 2 (arrows). Compare size with red blood cells (rbc) and a macrophage (mo). (B) Tachyzoites in groups (arrows) and individuals (arrowheads) in sections of skin. Immunohistochemical stain with anti-N. caninum antibody. (C) Tissue cyst in section of brain. Note thick tissue cyst wall (arrow) enclosing bradyzoites (arrows). Toluidine blue stain. (D) Unsporulated oocyst with an individual sporont (arrow). Unstained. (E) Sporulated oocyst (arrow). Unstained.
kjp-41-1-g002
Table 1.
Diagnosis of N. caninum-associated abortion in cattle from selected studies
Country No. of fetuses examined Percent infected Reference
Argentina 240 12.1 Moore et al. (2002)
Australia 729 21.0 Boulton et al. (1995)
Brazil 46 39.1 Corbellini et al. (2002)
Germany 135 12.6 Sondgen et al. (2001)
Mexico 211 77 Morales et al. (2001)
Switzerland 242 21.0 Sager et al. (2001)
The Netherlands 2,053 17 Wouda et al. (1997)
USA 698 24.4 Anderson et al. (1991); Thurmond et al. (1995)
USA 266 42.5 Anderson et al. (1995)
Table 2.
Neospora caninum isolates from cattle
Country Strain Source Reference
Australia NC-Nowra 7-day old calf Miller et al. (2002)
Italy NC-PVI 45-day old calf Magnino et al. (1999)
Italy NC-PGI 8-month old calf Fioretti et al. (2000)
Japan JPA-1 Clinical calf Yamane et al. (1997)
Japan BT-3 Adult cow Sawada et al. (2000)
Korea KBA-1 1 day-old calf Kim et al. (2000)
Korea KBA-2 Fetus Kim et al. (2000)
Portugal NC-Porto1 Fetus Canada et al. (2002)
Sweden NC-SweB1 Stillborn Stenlund et al. (1997)
U.K NC-LivB1 Stillborn calf Davison et al. (1999)
U.K NC-LivB2 Fetus Trees and Williams (2000)
USA BPA-1 Fetus Conrad et al. (1993)
USA BPA-2 Fetus Conrad et al. (1993)
USA BPA-3 Clinical calf Barr et al. (1993)
USA BPA-4 Clinical calf Barr et al. (1993)
USA NC-Beef Clinical calf McAllister et al. (2000)
USA NC-Illinois Clinical calf Gondim et al. (2002)
Table 3.
Recognized isolates of Neospora caninum from dogs
Strain designation Country Reference
NC-6- Argentinaa) Argentina Basso et al. (2001a)
NC-Bahiab) Brazil Gondim et al. (2001)
NC-GER1b) Germany Peters et al. (2000)
NC-livb) UK Barber et al. (1995)
NC-1b) USA Dubey et al. (1988b)
NC-2b) USA Hay et al. (1990)
NC-3b) USA Cuddon et al. (1992)
NC-4b) USA Dubey et al. (1998a)
NC-5b) USA Dubey et al. (1998a)
CN-1 USA Marsh et al. (1998)

a) From feces of a dog.

b) From tissues of congenitally-infected dogs.

Table 4.
Seroprevalence of Neospora caninum antibodies in water buffaloes
Country No. of animals Type Testa) Cut-off value % Positive Reference
Brazil 222 Dairy NAT 1:40 53 Fujii et al. (2001)
IFAT 1:25 64
Egypt 75 Meat NAT 1:40 60 Dubey et al. (1998b)
Italy 1,377 Dairy IFAT 1:200 34.6 Guarino et al. (2000)
Vietnam 200 Meat IFAT 1:200 1.5 Huong et al. (1998)
ELISA 0.2 1.5

a) NAT = Neospora agglutination test, IFAT = Indirect flourescent antibody test, ELISA = Enzyme-linked immunoabsorbent assay.

Table 5.
Seroprevalence of Neospora caninum antibodies in horses
Country No. of animals Test Cut-off value % Positive References
Argentina 76 NAT 1:40 0 Dubey et al. (1999d)
Brazil 101 NAT 1:40 0 Dubey et al. (1999c)
France 434 NAT 1:40 23 Pitel et al. (2001)
USA 296 NAT 1:40 21.3 Dubey et al. (1999b)
536 IFAT 1:50 11.5 Cheadle et al. (1999b)
208 IFAT 1:100 17 Vardeleon et al. (2001)
300 IFAT 1:50 10 McDole et al. (2002)
South Korea 191 IFAT 1:100 2 Gupta et al. (2002)
Table 6.
Seroprevalence of Neospora caninum antibodies in wildlife
Animal species Country No. examined Test % Positive Reference
Red fox (Vulpes vulpes) Belgium 123 IFAT 78 Buxton et al. (1997a)
Ireland 70 IFAT 1.4 Wolfe et al. (2001)
Spain 122 PCR 10.7 Almeira et al. (2002)
Sweden 221 ELISA 0 Jakubek et al. (2001)
UK 52 IFAT 2 Barber et al. (1997)
UK 16 IFAT 6 Simpson et al. (1997)
Gray foxes (Urocyon cinereoargeneteus) USA 26 NAT 15.4 Lindsay et al. (2001c)
Coyotes (Canis latrans) USA 52 IFAT 10 Lindsay et al. (1996a)
White-tailed deer (Odocoileus virginianus) USA 400 NAT 40.5 Dubey et al. (1999a)
305 NAT 48 Lindsay et al. (2002)
Australian dingos (Canis familiaris dingo) Australia 169 IFAT 15.9 Barber et al. (1997)
Chiloe fox (Pseudolapex fulvipes) 2 IFAT 100 Patitucci et al. (2001)
Lions (Panthera leo) S. Africa 18 IFAT 16.6 Cheadle et al. (1999a)
Cheetah (Acinonyx jubatus) S. Africa 16 IFAT 6.3 Cheadle et al. (1999a)
Raccoons (Procyon lotor) USA 95 NAT 10 Lindsay et al. (2001b)
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