Strongyloides stercoralis can cause systemic infection, termed strongyloidiasis, and gastrointestinal ulcer disease in immunocompromised patients. However, to our knowledge, there are no reported cases of comorbid gastric adenocarcinoma and S. stercoralis infection. Here, we report a case of an 81-year-old Korean man who presented with S. stercoralis infection coexisting with early gastric adenocarcinoma (T1aN0M0). S. stercoralis eggs, rhabditiform larvae, and adult females were observed in normal gastric and duodenal crypts. They were also observed in atypical glands representative of adenocarcinoma and adenoma. Preliminary laboratory tests revealed mild neutrophilic and eosinophilic leukocytosis. A routine stool test failed to detect rhabditiform larvae in the patient’s fecal sample; however, S. stercoralis was identified by PCR amplification and 18S rRNA sequencing using genomic DNA extracted from formalin-fixed paraffin-embedded tissues. Postoperatively, the patient had a persistent fever and was treated with albendazole for 7 days, which alleviated the fever. The patient was followed-up by monitoring and laboratory testing for 4 months postoperatively, and no abnormalities were observed thus far. The fact that S. stercoralis infection may be fatal in immunocompromised patients should be kept in mind when assessing high-risk patients.
Relationship between parasites and lung cancer: Unveiling the link Mariam T. El Khadrawe, Nahla El Skhawy, Maha M. Eissa Tropical Medicine & International Health.2025; 30(7): 613. CrossRef
NEOPLASIA AND PROLIFERATIVE LESIONS IN FREE-RANGING MOUNTAIN AND GRAUER'S GORILLAS (GORILLA BERINGEI) Maya L. Iyer, Kirsten V. Gilardi, Michael R. Cranfield, Sarah M. Corner, Eddy Kambale Syaluha, Jean Bosco Noheri, Benard Ssebide, Jean Felix Kinani, Fred Nizeyimana, Ricky Okwir Okello, Julius Nziza, Martin Kabuyaya, Methode Bahizi, Richard Muvunyi, Elisa Journal of Zoo and Wildlife Medicine.2025;[Epub] CrossRef
Gastroduodenal Strongyloidiasis Diagnosed during Iron Deficiency Anemia Workup Malek Kreidieh, Neville Mobarakai, Sherif Andrawes, Robert Colef, Lara Kreidieh, Hassan Al Moussawi, Jean M. Chalhoub Case Reports in Gastroenterology.2025; 19(1): 467. CrossRef
The Parasitism and Tumors Carcinogenesis: A Review Subject Ahmed Salih Alshewered Acta Parasitologica.2024; 69(1): 183. CrossRef
A case of disseminated strongyloidiasis diagnosed by worms in the urinary sediment Young-Ha Lee Parasites, Hosts and Diseases.2024; 62(2): 238. CrossRef
Mining parasites for their potential as novel therapeutic agents against cancer Neha Sylvia Walter, Shalmoli Bhattacharyya Medical Oncology.2024;[Epub] CrossRef
Association between Some Helminths and Tumorigenesis through
Immunological and Biochemical Factors Maryam Fasihi-Karami, Reza Afrisham, Saina Karami, Ehsan Beigzadeh, Forough Kazemi Current Cancer Therapy Reviews.2023; 19(2): 96. CrossRef
STRONGYLOIDES STERCORALIS: A RARE CASE DIAGNOSED WITH ESOPHAGEAL SWAB SAMPLE Arzu Hazal AYDIN, Buse BAYAZIT GÖZÜKÜÇÜK, Nesrin TURHAN Kırıkkale Üniversitesi Tıp Fakültesi Dergisi.2023; 25(1): 166. CrossRef
Is Gastric Involvement by Strongyloides stercoralis in an Immunocompetent Patient a Common Finding? A Case Report and Review of the Literature Irene Pecorella, Tom Richard Okello, Gaia Ciardi, David Martin Ogwang Acta Parasitologica.2022; 67(1): 94. CrossRef
Seropositivity Rates of Strongyloides stercoralis Antibody in the Southeastern Region of Republic of Korea: A Single-Center Retrospective Study Taehwa Kim, Seungjin Lim The Korean Journal of Parasitology.2022; 60(3): 181. CrossRef
Strongyloides Hyperinfection Causing Gastrointestinal Bleeding and Bacteremia in an Immunocompromised Patient Juan Carlos De la Cruz Mayhua, Bisharah Rizvi Cureus.2021;[Epub] CrossRef
Bacterial and Parasitic Pathogens as Risk Factors for Cancers in the Gastrointestinal Tract: A Review of Current Epidemiological Knowledge Janneke W. Duijster, Eelco Franz, Jacques Neefjes, Lapo Mughini-Gras Frontiers in Microbiology.2021;[Epub] CrossRef
Colorectal Cancer Related to Chronic Strongyloides stercoralis Infection M. Sava, T. Huynh, A. Frugoli, L. Kong, M. Salehpour, B. Barrows Case Reports in Gastrointestinal Medicine.2020; 2020: 1. CrossRef
Phylogenetic Positioning of a Strongyloides stercoralis Isolate Recovered from a Korean Patient and Comparison with Other Asian Isolates Jaeho Bae, Mi Jin Jeong, Dong hoon Shin, Hyun Woo Kim, Sung Ho Ahn, Jun Ho Choi, Hak Sun Yu The Korean Journal of Parasitology.2020; 58(6): 689. CrossRef
Microbiome signatures in prostate cancer Sagarika Banerjee, James C Alwine, Zhi Wei, Tian Tian, Natalie Shih, Colin Sperling, Thomas Guzzo, Michael D Feldman, Erle S Robertson Carcinogenesis.2019; 40(6): 749. CrossRef
Pathologic Features of Infectious Gastritis Eric U. Yee, Enoch Kuo, Jeffrey D. Goldsmith Advances in Anatomic Pathology.2018; 25(4): 238. CrossRef
The Clean India Mission: Public and animal health benefits Rashmi Thakur, Balbir Bagicha Singh, Prateek Jindal, Rabinder Singh Aulakh, Jatinder Paul Singh Gill Acta Tropica.2018; 186: 5. CrossRef
Compensatory gastric stretching following subtotal gastric resection due to gastric adenocarcinoma in a diamond python (Morelia spilota spilota) HR Baron, J Šlapeta, SL Donahoe, RTJ Doneley, DN Phalen Australian Veterinary Journal.2018; 96(12): 481. CrossRef
Parasite Infection, Carcinogenesis and Human Malignancy Hoang van Tong, Paul J. Brindley, Christian G. Meyer, Thirumalaisamy P. Velavan EBioMedicine.2017; 15: 12. CrossRef
Gastric Strongyloidiasis: Report of 2 Cases and Brief Review of the Literature Rawia Mohamed, Mowafak M. Hamodat, Mousa A. Al-Abbadi Laboratory Medicine.2017; 48(1): 93. CrossRef
Strongyloidiasis Current Status with Emphasis in Diagnosis and Drug Research Tiago Mendes, Karen Minori, Marlene Ueta, Danilo Ciccone Miguel, Silmara Marques Allegretti Journal of Parasitology Research.2017; 2017: 1. CrossRef
A case of adenocarcinoma developed in the small intestine with chronic strongyloidiasis Satoshi Ishikawa, Tamaki Maeda, Kimiaki Hattori, Takahiro Watanabe, Takanori Kuramoto, Saori Ueno, Goro Ueno, Tadahiro Yamada, Akifumi Kanazawa, Masahiro Sakaguchi, Yoshitane Tsukamoto Clinical Journal of Gastroenterology.2017; 10(6): 519. CrossRef
Colorectal Cancer Associated with Strongyloides stercoralis Colitis Carmine Catalano, Joshua Aron, Raghav Bansal, Anatoly Leytin ACG Case Reports Journal.2017; 4(1): e104. CrossRef
Carcinogenesis associated with parasites other than Schistosoma, Opisthorchis and Clonorchis: A systematic review Claudia Machicado, Luis A. Marcos International Journal of Cancer.2016; 138(12): 2915. CrossRef
