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Kittisak Sawanyawisuth	3 Articles
A Recombinant Matrix Metalloproteinase Protein from Gnathostoma spinigerum for Serodiagnosis of Neurognathostomiasis Penchom Janwan, Pewpan M. Intapan, Hiroshi Yamasaki, Porntip Laummaunwai, Kittisak Sawanyawisuth, Chaisiri Wongkham, Chatchai Tayapiwatana, Amnat Kitkhuandee, Viraphong Lulitanond, Yukifumi Nawa, Wanchai Maleewong Korean J Parasitol 2013;51(6):751-754. Published online December 31, 2013 DOI: https://doi.org/10.3347/kjp.2013.51.6.751 Abstract PDF Neurognathostomiasis is a severe form of human gnathostomiasis which can lead to disease and death. Diagnosis of neurognathostomiasis is made presumptively by using clinical manifestations. Immunoblotting, which recognizes antigenic components of molecular mass 21 kDa and 24 kDa in larval extracts of Gnathostoma spinigerum (Gs 21/24), has high sensitivity and specificity for diagnosis of neurognathostomiasis. However, only very small amounts of the Gs 21/24 antigens can be prepared from parasites harvested from natural or experimental animals. To overcome this problem, we recently produced a recombinant matrix metalloproteinase (rMMP) protein from G. spinigerum. In this study, we evaluated this rMMP alongside the Gs 21/24 antigens for serodiagnosis of human neurognathostomiasis. We studied sera from 40 patients from Srinagarind Hospital, Khon Kaen University, Thailand, with clinical criteria consistent with those of neurognathostomiasis, and sera from 30 healthy control adults from Thailand. All sera were tested for specific IgG antibodies against both G. spinigerum crude larval extract and rMMP protein using immunoblot analysis. The sensitivity and specificity for both antigenic preparations were all 100%. These results show that G. spinigerum rMMP protein can be used as an alternative diagnostic antigen, in place of larval extract, for serodiagnosis of neurognathostomiasis. Citations Citations to this article as recorded by Protein and antigen profiles of third-stage larvae of Gnathostoma spinigerum assessed with next-generation sequencing transcriptomic information Kathyleen Nogrado, Tipparat Thiangtrongjit, Poom Adisakwattana, Paron Dekumyoy, Sant Muangnoicharoen, Charin Thawornkuno, Onrapak Reamtong Scientific Reports.2022;[Epub] CrossRef Development of Immunochromatographic Test Kit for Rapid Detection of Specific IgG4 Antibody in Whole-Blood Samples for Diagnosis of Human Gnathostomiasis Penchom Janwan, Pewpan M. Intapan, Lakkhana Sadaow, Rutchanee Rodpai, Hiroshi Yamasaki, Patcharaporn Boonroumkaew, Oranuch Sanpool, Tongjit Thanchomnang, Phuangphaka Sadee, Wanchai Maleewong Diagnostics.2021; 11(5): 862. CrossRef Proteomics of Gnathostomiasis: A Way Forward for Diagnosis and Treatment Development Tipparat Thiangtrongjit, Kathyleen Nogrado, Thawatchai Ketboonlue, Preeyarat Malaitong, Poom Adisakwattana, Onrapak Reamtong Pathogens.2021; 10(9): 1080. CrossRef Combining lexical and context features for automatic ontology extension Sara Althubaiti, Şenay Kafkas, Marwa Abdelhakim, Robert Hoehndorf Journal of Biomedical Semantics.2020;[Epub] CrossRef Human gnathostomiasis: a neglected food-borne zoonosis Guo-Hua Liu, Miao-Miao Sun, Hany M. Elsheikha, Yi-Tian Fu, Hiromu Sugiyama, Katsuhiko Ando, Woon-Mok Sohn, Xing-Quan Zhu, Chaoqun Yao Parasites & Vectors.2020;[Epub] CrossRef Surveillance and diagnosis of zoonotic foodborne parasites Reza Zolfaghari Emameh, Sami Purmonen, Antti Sukura, Seppo Parkkila Food Science & Nutrition.2018; 6(1): 3. CrossRef 8,872 View 101 Download Crossref Detection of Gnathostoma spinigerum Antibodies in Sera of Non-Traumatic Subarachnoid Hemorrhage Patients in Thailand Amnat Kitkhuandee, Waranon Munkong, Kittisak Sawanyawisuth, Penchom Janwan, Wanchai Maleewong, Pewpan M. Intapan Korean J Parasitol 2013;51(6):755-757. Published online December 31, 2013 DOI: https://doi.org/10.3347/kjp.2013.51.6.755 Abstract PDF Gnathostoma spinigerum can cause subarachnoid hemorrhage (SAH). The detection of specific antibodies in serum against G. spinigerum antigen is helpful for diagnosis of neurognathostomiasis. There is limited data on the frequency of G. spinigerum infection in non-traumatic SAH. A series of patients diagnosed as non-traumatic SAH at the Srinagarind Hospital, Khon Kaen University, Thailand between January 2011 and January 2013 were studied. CT or MR imaging of the brain was used for diagnosis of SAH. Patients were categorized as aneurysmal subarachnoid hemorrhage (A-SAH) or non-aneurysmal subarachnoid hemorrhage (NA-SAH) according to the results of cerebral angiograms. The presence of specific antibodies in serum against 21- or 24-kDa G. spinigerum antigen was determined using the immunoblot technique. The detection rate of antibodies was compared between the 2 groups. Of the 118 non-traumatic SAH patients for whom cerebral angiogram and immunoblot data were available, 80 (67.8%) patients had A-SAH, whereas 38 (32.2%) had NA-SAH. Overall, 23.7% were positive for specific antibodies against 21- and/or 24-kDa G. spinigerum antigen. No significant differences were found in the positive rate of specific antibodies against G. spinigerum in both groups (P-value=0.350). 9,556 View 76 Download Clinical Manifestations of Eosinophilic Meningitis Due to Infection with Angiostrongylus cantonensis in Children Kittisak Sawanyawisuth, Jarin Chindaprasirt, Vichai Senthong, Panita Limpawattana, Narong Auvichayapat, Sompon Tassniyom, Verajit Chotmongkol, Wanchai Maleewong, Pewpan M. Intapan Korean J Parasitol 2013;51(6):735-738. Published online December 31, 2013 DOI: https://doi.org/10.3347/kjp.2013.51.6.735 Abstract PDF Eosinophilic meningitis, caused by the nematode Angiostrongylus cantonensis, is prevalent in northeastern Thailand, most commonly in adults. Data regarding clinical manifestations of this condition in children is limited and may be different those in adults. A chart review was done on 19 eosinophilic meningitis patients aged less than 15 years in Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Thailand. Clinical manifestations and outcomes were reported using descriptive statistics. All patients had presented with severe headache. Most patients were males, had fever, nausea or vomiting, stiffness of the neck, and a history of snail ingestion. Six patients had papilledema or cranial nerve palsies. It was shown that the clinical manifestations of eosinophilic meningitis due to A. cantonensis in children are different from those in adult patients. Fever, nausea, vomiting, hepatomegaly, neck stiffness, and cranial nerve palsies were all more common in children than in adults. Citations Citations to this article as recorded by Neuroangiostrongyliasis: Updated Provisional Guidelines for Diagnosis and Case Definitions Carlos Graeff-Teixeira, Kittisak Sawanyawisuth, Shan Lv, William Sears, Zhaily González Rodríguez, Hilda Hernández Álvarez, Pedro Casanova Arias, Leticia Karolini Walger Schultz, Alicia Rojas, John Jacob, Susan Jarvi, Kenton Kramer Pathogens.2023; 12(4): 624. CrossRef Clinical Characteristics and Treatment Outcome of Eosinophilic Meningoencephalitis in South Indian Children: Experience From a Prospective Registry Kollencheri Puthenveettil Vinayan, Sai Chandar Dudipala, Arun Grace Roy, Vaishakh Anand Pediatric Neurology.2023; 147: 9. CrossRef Clinical Efficacy and Safety of Albendazole and Other Benzimidazole Anthelmintics for Rat Lungworm Disease (Neuroangiostrongyliasis): A Systematic Analysis of Clinical Reports and Animal Studies John Jacob, Argon Steel, Zhain Lin, Fiona Berger, Katrin Zöeller, Susan Jarvi Clinical Infectious Diseases.2022; 74(7): 1293. CrossRef A Rare Etiology for Ascending Paralysis in an Infant Keisuke Abe, Chanel Casamina, Natascha Ching, Keith K Abe, Marian Melish, Karen S Thompson, Asim A Ahmed, Prashant J Purohit Journal of the Pediatric Infectious Diseases Society.2022; 11(10): 448. CrossRef Paratenic hosts of Angiostrongylus cantonensis and their relation to human neuroangiostrongyliasis globally Helena C. Turck, Mark T. Fox, Robert H. Cowie One Health.2022; 15: 100426. CrossRef The application of metagenomic next-generation sequencing for Angiostrongylus eosinophilic meningitis in a pediatric patient: A case report Jing Liu, Jinhao Tao, Weiming Chen, Tingting Wang, Xin Chen, Meili Shen, Qiuxiang Ou, Yunjian Zhang, Yifeng Ding, Jufang Wu, Xunjia Cheng, Guoping Lu, Gangfeng Yan Frontiers in Public Health.2022;[Epub] CrossRef Eosinophilic meningitis epidemiological data from a national database in Thailand’s Department of Disease Control: a pragmatic, retrospective analytical study Sittichai Khamsai, Verajit Chotmongkol, Somsak Tiamkao, Wanchai Maleewong, Panita Limpawattana, Watchara Boonsawat, Bundit Sawunyavisuth, Noppadol Aekphachaisawat, Kittisak Sawanyawisuth Orphanet Journal of Rare Diseases.2022;[Epub] CrossRef Gross, microscopic, radiologic, echocardiographic and haematological findings in rats experimentally infected withAngiostrongylus cantonensis Matthew K. Wun, Sarah Davies, Derek Spielman, Rogan Lee, Doug Hayward, Richard Malik Parasitology.2021; 148(2): 159. CrossRef Guidelines for the diagnosis and treatment of neuroangiostrongyliasis: updated recommendations Vernon Ansdell, Kenton J. Kramer, Jourdan K. McMillan, William L. Gosnell, Gerald S. Murphy, B C Meyer, Elizabeth U. Blalock, Johnnie Yates, Louis Lteif, Olivia A. Smith, Marian Melish Parasitology.2021; 148(2): 227. CrossRef Tetraventricular Hydrocephalus Following Eosinophilic Meningitis due to Angiostrongylus cantonensis in a 14-Month-Old Boy From Mayotte: A Case Report Chiara Cattaneo, Marion Hoarau, Sophie Valois, Abdourahim Chamouine, Yacouba Dembele, Luis Collet, Raphaëlle Sarton Open Forum Infectious Diseases.2021;[Epub] CrossRef Eosinophilic Meningitis due to Angiostrongylus cantonensis in Children Hai Thanh Phan, Kiem Hao Tran, Huu Son Nguyen Case Reports in Neurology.2021; 13(1): 184. CrossRef Next-generation sequencing specifies Angiostrongylus eosinophilic meningoencephalitis in infants Mei Xie, Zhen Zhou, Suhua Guo, Zengqing Li, Hui Zhao, Jiusheng Deng Medicine.2019; 98(35): e16985. CrossRef Magnetic resonance imaging findings and clinical manifestations in cerebral angiostrongyliasis from Dali, China Bin Yang, Ling Yang, Yili Chen, Guangming Lu Brain and Behavior.2019;[Epub] CrossRef Geographic distribution of Angiostrongylus cantonensis in wild rats (Rattus rattus) and terrestrial snails in Florida, USA Heather D. Stockdale Walden, John D. Slapcinsky, Shannon Roff, Jorge Mendieta Calle, Zakia Diaz Goodwin, Jere Stern, Rachel Corlett, Julia Conway, Antoinette McIntosh, Heike Lutermann PLOS ONE.2017; 12(5): e0177910. CrossRef Case 1: Fever and Ataxia in a Toddler with Pica Megan H. Tucker, Jonathan Holmes, Susan Harley, Maria Roca Garcia, Haidee Custodio Pediatrics In Review.2017; 38(9): 435. CrossRef Angiostrongylus cantonensis: a review of its distribution, molecular biology and clinical significance as a human pathogen JOEL BARRATT, DOUGLAS CHAN, INDY SANDARADURA, RICHARD MALIK, DEREK SPIELMAN, ROGAN LEE, DEBORAH MARRIOTT, JOHN HARKNESS, JOHN ELLIS, DAMIEN STARK Parasitology.2016; 143(9): 1087. CrossRef L’angiostrongylose humaine : une maladie tropicale négligée Loïc Epelboin, Louis Collet, Maxime Raz, Nicolas Villemant, Denis Malvy, Renaud Blondé Revue Francophone des Laboratoires.2016; 2016(483): 45. CrossRef *Development of Lateral Flow Immunoassay for Antigen Detection in Human Angiostrongylus cantonensis* Infection** Mu-Xin Chen, Jia-Xu Chen, Shao-Hong Chen, Da-Na Huang, Lin Ai, Ren-Li Zhang The Korean Journal of Parasitology.2016; 54(3): 375. CrossRef Angiostrongylus cantonensisInfection: A Cause of Fever of Unknown Origin in Pediatric Patients Catherine E. Foster, Erin G. Nicholson, Angela C. Chun, Maya Gharfeh, Sara Anvari, Filiz O. Seeborg, Michael A. Lopez, Judith R. Campbell, Lucila Marquez, Jeffrey R. Starke, Debra L. Palazzi Clinical Infectious Diseases.2016; 63(11): 1475. CrossRef Angiostrongylus cantonensis Infection on Mayotte Island, Indian Ocean, 2007-2012 Loïc Epelboin, Renaud Blondé, Abdourahim Chamouine, Alexandra Chrisment, Laure Diancourt, Nicolas Villemant, Agnès Atale, Claire Cadix, Valérie Caro, Denis Malvy, Louis Collet, Malcolm Jones PLOS Neglected Tropical Diseases.2016; 10(5): e0004635. CrossRef Feline lungworms unlock a novel mode of parasite transmission Vito Colella, Alessio Giannelli, Emanuele Brianti, Rafael Antonio Nascimento Ramos, Cinzia Cantacessi, Filipe Dantas-Torres, Domenico Otranto Scientific Reports.2015;[Epub] CrossRef 10,319 View 103 Download Crossref