Parasites, Hosts and Diseases

Skip to main navigation Skip to main content

OPEN ACCESS

Page Path

HOME
BROWSE ARTICLES

Author index detail contents
Lee-Soo Kim	1 Article
Persisting antibody reaction in paragonimiasis after praziquantel treatment is elicited mainly by egg antigens Seung-Yull Cho, Yoon Kong, Doo-Hee Yun, Shin-Yong Kang, Lee-Soo Kim, Young-Bae Chung, Hyun-Jong Yang Korean J Parasitol 2000;38(2):75-84. Published online June 30, 2000 DOI: https://doi.org/10.3347/kjp.2000.38.2.75 Abstract PDF Antibody responses in serum and cerebrospinal fluid (CSF) samples from patients with active and chronic paragonimiasis and in sera from patients on whom follow-up studies were done after praziquantel treatment were analyzed using antigens of Paragonimus westermani prepared from eggs, metacercariae, juveniles of 4- and 7-week old, adult worms and recombinant protein of 28 kDa cruzipain-like cysteine protease (rPw28CCP). The patient sera/CSFs of active and chronic paragonimiasis revealed strong antibody reactions against the crude extracts of 4- and 7-week old juveniles as well as against those from egg and adult. rPw28CCP also showed specific reaction to the sera with active paragonimiasis. After the treatment, levels of specific antibodies in the sera gradually decreased to negative range in most patients. In some cases with persisting high antibody levels, however, the reactions at 27 kDa egg protein were sustained throughout the observation period of 34 months. The reactions at 35 and 32 kDa in adult extract and rPw28CCP disappeared rapidly after the treatment. Persistent antibody reactions even after successful treatment are provoked by continuous antigenic challenge from eggs which were not resolved by treatment. Citations Citations to this article as recorded by Brain hemorrhage associated with a mixed parasitic infection in a foreign technical intern trainee: A case report Koki Satake, Jin Kikuchi, Mio Kokubo-Tanaka, Takayasu Ando, Ryusei Tanaka, Mikinori Kannae, Nobuhisa Hirayu, Haruhiko Maruyama, Osamu Takasu, Motohiro Morioka Journal of Infection and Chemotherapy.2026; 32(4): 102944. CrossRef Cerebral paragonimiasis: Clinicoradiological features and serodiagnosis using recombinant yolk ferritin Jeong-Geun Kim, Chun-Seob Ahn, Insug Kang, Jong-Wook Shin, Hae-Bong Jeong, Yukifumi Nawa, Yoon Kong, Chukwunonso Nzelu PLOS Neglected Tropical Diseases.2022; 16(3): e0010240. CrossRef Paragonimiasis presenting as an acute hemorrhagic stroke Neha Paranjape, Victor Nunez, Demetrius Dicks IDCases.2021; 26: e01287. CrossRef Lineage-specific expansion and loss of tyrosinase genes across platyhelminths and their induction profiles in the carcinogenic oriental liver fluke, Clonorchis sinensis SEON-HEE KIM, YOUNG-AN BAE Parasitology.2017; 144(10): 1316. CrossRef Parallel ELISAs using crude soluble antigen and excretory-secretory antigen for improved serodiagnosis of amoebic liver abscess Weng-Kin Wong, Phiaw-Chong Foo, Alfonso Olivos-Garcia, Rahmah Noordin, Zeehaida Mohamed, Nurulhasanah Othman, Ling-Ling Few, Boon-Huat Lim Acta Tropica.2017; 172: 208. CrossRef Cerebral Paragonimiasis Presenting with Sudden Death Gary W. Procop, Annie Cowell, Sharon L. Reed, Deirdre E. Amaro, Marion J. Tuohy, Jacquelyn Morhaime The American Journal of Tropical Medicine and Hygiene.2016; 95(6): 1424. CrossRef Molecular and biochemical characterization ofParagonimus westermanityrosinase Y.-A. BAE, S.-H. KIM, C.-S. AHN, J.-G. KIM, Y. KONG Parasitology.2015; 142(6): 807. CrossRef Expression pattern and substrate specificity of Clonorchis sinensis tyrosinases Young-An Bae, Guo-Bin Cai, Seon-Hee Kim, Woon-Mok Sohn, Yoon Kong International Journal for Parasitology.2013; 43(11): 891. CrossRef A Case of Incidentally Diagnosed Adrenal Paragonimiasis Shin-Ae Park, Seung-Hwan Lee, Seung-Hyun Ko, Jun-Gi Kim, Soo-Youn Park, Jin-Young Yoo, Ho-Woo Nam, Yu-Bae Ahn Endocrinology and Metabolism.2011; 26(1): 97. CrossRef Paragonimus westermani: Identification and characterization of the fasciclin I domain-containing protein Su-Min Song, Jong-Won Shin, Jefferson V. de Guzman, Jin Kim, Hak-Sun Yu, Bijay Kumar Jha, Hyun-Hee Kong, Yeonchul Hong, Dong-Il Chung Experimental Parasitology.2010; 125(2): 76. CrossRef Molecular cloning and characterization of a major egg antigen in Paragonimus westermani and its use in ELISA for the immunodiagnosis of paragonimiasis Jae Sik Lee, Jongweon Lee, Sun Hyun Kim, Tai-Soon Yong Parasitology Research.2007; 100(4): 677. CrossRef Differential expression of Paragonimus westermani eggshell proteins during the developmental stages Young-An Bae, Seon-Hee Kim, Guo-Bin Cai, Eung-Goo Lee, Tong-Soo Kim, Takeshi Agatsuma, Yoon Kong International Journal for Parasitology.2007; 37(3-4): 295. CrossRef Excretory-secretory antigen is better than crude antigen for the serodiagnosis of clonorchiasis by ELISA Min-Ho Choi, Il Chan Park, Shunyu Li, Sung-Tae Hong The Korean Journal of Parasitology.2003; 41(1): 35. CrossRef 9,752 View 71 Download Crossref