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M. Khyrul Islam	3 Articles
Persistent infection with Strongyloides venezuelensis in the Mongolian gerbil (Meriones unguiculatus) Byeong-Kirl Baek, In-Soo Whang, M. Khyrul Islam, Byeong-Soo Kim, Ibulaimu Kakoma Korean J Parasitol 2002;40(4):181-186. Published online December 30, 2002 DOI: https://doi.org/10.3347/kjp.2002.40.4.181 Abstract PDF To examine the fate of Strongyloides venezuelensis, Mongolian gerbils (Meriones unguicalatus) were orally infected with 1,000 L₃ larvae per animal. Altogether, 50 gerbils divided into 5 groups of 10 each were monitored for a period of 570 days to document the kinetics of faecal egg output, adults worm population, morphological development, fecundity, and hematological changes including peripheral blood eosinophilia. This study chronicled a life long parasitism of S. venezuelensis in the gerbil host, and showed that S. venezuelensis infection was quite stable throughout the course of infection and the worms maintained their normal development as evidenced by their body dimension. A progressive loss of body condition of the infected gerbils was observed as the level of infection advanced. However, no detectable pathological changes were observed in the gastrointestinal tract. The present findings indicate that an immunocompetent host, such as the Mongolian gerbil, can serve as a life long carrier model of S. venezuelensis if the worms are not expelled within 570 days after infection. Citations Citations to this article as recorded by A century-old methodology revisited: Quantitative standardisation for collection of Strongyloides venezuelensis eggs and current applications A.N. Sales, D. Pujoni, A.L. Melo, V.L.T. Mati Journal of Helminthology.2026;[Epub] CrossRef Gastrointestinal effects of ivermectin treatment in rats infected with Strongyloides venezuelensis Jalvita C. Mendonça, Loyane A. Gama, Andrieli T. Hauschildt, Luciana A. Corá, Madileine F. Américo Acta Tropica.2019; 194: 69. CrossRef Strongyloides ratti and S. venezuelensis – rodent models of Strongyloides infection MARK VINEY, TAISEI KIKUCHI Parasitology.2017; 144(3): 285. CrossRef Parasitological and transcriptomic comparison of Strongyloides ratti infections in natural and in suboptimal permissive hosts Tegegn G. Jaleta, Christian Rödelsperger, Adrian Streit Experimental Parasitology.2017; 180: 112. CrossRef Callithrix penicillata as a nonhuman primate model for strongyloidiasis Alan Lane de Melo, Vitor Luís Tenório Mati, Wanderlany Amâncio Martins Primates.2012; 53(3): 303. CrossRef Role of angiogenic factors in acute experimental Strongyloides venezuelensis infection F. SHARIATI, J. L. PÉREZ-ARELLANO, J. LÓPEZ-ABÁN, A. M. EL BEHAIRY, A. MURO Parasite Immunology.2010; 32(6): 430. CrossRef Migration of Strongyloides venezuelensis in Rats after Oral Inoculation of Free-Living Infective Larvae Kiku MATSUDA, Byeong-Su KIM, In-Soo WHANG, Chae-Woong LIM, Byeong-Kirl BAEK Journal of Veterinary Medical Science.2003; 65(9): 971. CrossRef 8,093 View 59 Download Crossref Partial cross-resistance between Strongyloides venezuelensis and Nippostrongylus brasiliensis in rats Byeong-Kirl Baek, M. Khyrul Islam, Jin-Ho Kim, John-Wha Lee, Jin Hur Korean J Parasitol 1999;37(2):101-107. Published online June 30, 1999 DOI: https://doi.org/10.3347/kjp.1999.37.2.101 Abstract PDF Rats were immunized through an initial infection with 1,000 filariform larvae (L₃) of Nippostrongylus brasiliensis and after complete expulsion of worms they were challenged with 1,000 L₃ of Strongyloides venezuelensis to investigate whether cross-resistance developed against a heterologous parasite. Nippostrongylus brasiliensis-immunized rats developed a partial cross-resistance against S. venezuelensis migrating larvae (MSL₃) in the lungs and adult worms in the small intestine. The population of MSL₃ in the lungs were significantly lower (P<0.05) in immunized rats (22.0 ± 7.4) compared with controls (105.0 ± 27.6). The populations of adult worms, egg output and fecundity were initially decreased but from day 14 post-challenge they did not show any significant difference between immunized and control rats. However, the length of worm in immunized rat was revealed as retardation. Peripheral blood eosinophilia was significantly decreased (P<0.05) on day 7 post-challenge and then gradually increased, which peaked on day 42 post-challenge when most of the worms were expelled. These results suggest that peripheral blood eosinophilia is strongly involved in the worm establishment and expulsion mechanisms. Citations Citations to this article as recorded by Systemic Immune Modulation by Gastrointestinal Nematodes Darshan N. Kasal, Lindsey M. Warner, Astra S. Bryant, Elia Tait Wojno, Jakob von Moltke Annual Review of Immunology .2024; 42(1): 259. CrossRef Intestinal helminth infection transforms the CD4+ T cell composition of the skin Cajsa H. Classon, Muzhen Li, Ada Lerma Clavero, Junjie Ma, Xiaogang Feng, Christopher A. Tibbitt, Julian M. Stark, Rebeca Cardoso, Emma Ringqvist, Louis Boon, Eduardo J. Villablanca, Antonio Gigliotti Rothfuchs, Liv Eidsmo, Jonathan M. Coquet, Susanne Nyl Mucosal Immunology.2022; 15(2): 257. CrossRef Nematode-Infected Mice Acquire Resistance to Subsequent Infection With Unrelated Nematode by Inducing Highly Responsive Group 2 Innate Lymphoid Cells in the Lung Koubun Yasuda, Takumi Adachi, Atsuhide Koida, Kenji Nakanishi Frontiers in Immunology.2018;[Epub] CrossRef Biotic and abiotic effects on the intestinal helminth community of the brown ratRattus norvegicusfrom Rio de Janeiro, Brazil R.O. Simões, J.L. Luque, R. Gentile, M.C.S. Rosa, S. Costa-Neto, A. Maldonado Journal of Helminthology.2016; 90(1): 21. CrossRef Migratory route of Strongyloides venezuelensis in Lewis rats: Comparison of histological analyses and PCR Nelson Mendes Marra, Fernanda Chiuso-Minicucci, Gabriel Capella Machado, Sofia Fernanda Gonçalves Zorzella-Pezavento, Thaís Graziela Donegá França, Larissa Lumi Watanabe Ishikawa, Alessandro F.T. Amarante, Alexandrina Sartori, Mônica R.V. Amarante Experimental Parasitology.2011; 127(2): 334. CrossRef Migration of Strongyloides venezuelensis in Rats after Oral Inoculation of Free-Living Infective Larvae Kiku MATSUDA, Byeong-Su KIM, In-Soo WHANG, Chae-Woong LIM, Byeong-Kirl BAEK Journal of Veterinary Medical Science.2003; 65(9): 971. CrossRef 8,746 View 52 Download Crossref Effects of in vitro culture methods on morphological development and infectivity of Strongyloides venezuelensis filariform larvae M. Khyrul Islam, Kiku Matsuda, Jin-Ho Kim, Byeong-Kirl Baek Korean J Parasitol 1999;37(1):13-19. Published online March 31, 1999 DOI: https://doi.org/10.3347/kjp.1999.37.1.13 Abstract PDF The effects of in vitro culture methods on morphological development and infectivity of Strongyloides venezuelensis filariform larvae (L₃) to rats were investigated. A significantly higher body length was observed in L₃ from filter paper culture (597.3 ± 32.2 ?m) than those in fecal (509.9 ± 35.0 ?m) and nutrient broth culture (503.3 ± 31.0 ?m) (P<0.05). Larval infectivity was assessed by exposing rats to 1,000 L₃ from each culture and worms were recovered from the lungs and small intestines. Recovery rate of these worms did not show any significant difference. A significantly greater body length of adults was recorded in those corresponding to the L₃ harvested from filter paper (2,777.5 ± 204.4 ?m) and nutrient broth culture (2,732.5 ± 169.8 ?m) than those corresponding to the L₃ obtained from fecal culture (2,600.5 ± 172.4 ?m) (P<0.05). Although worm fecundity and EPG counts differed among culture methods but worm burdens and course of infection did not. These findings suggest that the methods of cultures have a significant effect on the morphological development of the larvae to the L₃ stage, but do not influence the infectivity to rats. Citations Citations to this article as recorded by A century-old methodology revisited: Quantitative standardisation for collection of Strongyloides venezuelensis eggs and current applications A.N. Sales, D. Pujoni, A.L. Melo, V.L.T. Mati Journal of Helminthology.2026;[Epub] CrossRef Venestatin from parasitic helminths interferes with receptor for advanced glycation end products (RAGE)-mediated immune responses to promote larval migration Daigo Tsubokawa, Taisei Kikuchi, Jae Man Lee, Takahiro Kusakabe, Yasuhiko Yamamoto, Haruhiko Maruyama, James B. Lok PLOS Pathogens.2021; 17(6): e1009649. CrossRef Strongyloides ratti and S. venezuelensis – rodent models of Strongyloides infection MARK VINEY, TAISEI KIKUCHI Parasitology.2017; 144(3): 285. CrossRef Venestatin, a Ca ++ -binding protein from the parasitic nematode Strongyloides venezuelensis , is involved in the larval migration process Daigo Tsubokawa, Takeshi Hatta, Taisei Kikuchi, Hiroki Maeda, Fusako Mikami, M. Abdul Alim, Haruhiko Maruyama, Naotoshi Tsuji International Journal for Parasitology.2017; 47(8): 501. CrossRef Viability of Strongyloides venezuelensis eggs and larvae in vermiculite containing the fungus Duddingtonia flagrans Laryssa Pinheiro Costa Silva, Carolina Magri Ferraz, Anderson Rocha Aguiar, Jackson Victor Araújo, Steveen Rios Ribeiro, Débora Goldner Rossi, Luanderson Queiroz Mendes, Fausto Edmundo Lima Pereira, Narcisa Imaculada Brant Moreira, Fabio Ribeiro Braga Parasitology Research.2017; 116(7): 2047. CrossRef Development of free-living stages of Strongyloides ratti under different temperature conditions Maki Sakamoto, Shoji Uga Parasitology Research.2013; 112(12): 4009. CrossRef Transcriptomic analysis of four developmental stages of Strongyloides venezuelensis Eiji Nagayasu, Yoshitoshi Ogura, Takehiko Itoh, Ayako Yoshida, Gunimala Chakraborty, Tetsuya Hayashi, Haruhiko Maruyama Parasitology International.2013; 62(1): 57. CrossRef Characterization of the protective response against a homologous challenge infection with Strongyloides venezuelensis in rats B.K Baek, M.K Islam, B.S Kim, C.W Lim, J Hur, A.O Oluoch, C.H Kim, I Kakoma Veterinary Parasitology.2003; 113(3-4): 217. CrossRef Persistent infection with Strongyloides venezuelensis in the Mongolian gerbil (Meriones unguiculatus) Byeong-Kirl Baek, In-Soo Whang, M. Khyrul Islam, Byeong-Soo Kim, Ibulaimu Kakoma The Korean Journal of Parasitology.2002; 40(4): 181. CrossRef Partial cross-resistance between Strongyloides venezuelensis and Nippostrongylus brasiliensis in rats Byeong-Kirl Baek, M. Khyrul Islam, Jin-Ho Kim, John-Wha Lee, Jin Hur The Korean Journal of Parasitology.1999; 37(2): 101. CrossRef 8,395 View 69 Download Crossref