Parasites, Hosts and Diseases

Skip to main navigation Skip to main content

OPEN ACCESS

Page Path

HOME
BROWSE ARTICLES

Author index detail contents
Mohammad Hashemnia	1 Article
Changing Patterns of Acute Phase Proteins and Inflammatory Mediators in Experimental Caprine Coccidiosis Mohammad Hashemnia, Azizollah Khodakaram-Tafti, Seyed Mostafa Razavi, Saeed Nazifi Korean J Parasitol 2011;49(3):213-219. Published online September 30, 2011 DOI: https://doi.org/10.3347/kjp.2011.49.3.213 Abstract PDF This experiment was conducted to assess the changing patterns and relative values of acute phase proteins and inflammatory cytokines in experimental caprine coccidiosis. Eighteen newborn kids were allocated to 3 equal groups. Two groups, A and B, were inoculated with a single dose of 1×10³ and1×10⁵ sporulated oocysts of Eimeria arloingi, respectively. The third group, C, received distilled water as the control. Blood samples were collected from the jugular vein of each kid in both groups before inoculation and at days 7, 14, 21, 28, 35, and 42 post-inoculation (PI), and the levels of haptoglobin (Hp), serum amyloid A (SAA), TNF-α, and IFN-γ were measured. For histopathological examinations, 2 kids were selected from each group, euthanized, and necropsied on day 42 PI. Mean Hp concentrations in groups A and B (0.34 and 0.68 g/L) at day 7 PI were 3.2 and 6.3 times higher than the levels before inoculation. The mean SAA concentrations in groups A and B (25.6 and 83.5 ?g/ml) at day 7 PI were 4.2 and 13.7 times higher than the levels before inoculation. The magnitude and duration of the Hp and SAA responses correlated well with the inoculation doses and the severity of the clinical signs and diarrhea in kids. These results were consistent with the histopathological features, which showed advanced widespread lesions in group B. In both groups, significant correlations were observed for TNF-α and IFN-γ with SAA and Hp, respectively. In conclusion, Hp and SAA can be useful non-specific diagnostic indicators in caprine coccidiosis. Citations Citations to this article as recorded by Global prevalence of Eimeria species in goats: a systematic review and meta-analysis Endris A. Ali, Abdul Ghafar, Juan C. Angeles-Hernandez, Muhammad Yaseen, Charles G. Gauci, Ian Beveridge, Sandra Baxendell, Abdul Jabbar Frontiers in Veterinary Science.2025;[Epub] CrossRef First-generation merozoites of caprine Eimeria christenseni are capable to invade and egress primary host endothelial cells in vitro L.M.R. Silva, A. Ruiz, E. Barba, S. Lopéz-Osorio, J.A. Molina, J.M. Molina, A. Taubert, C. Hermosilla Frontiers in Veterinary Science.2025;[Epub] CrossRef Acute phase response and oxidative stress in coccidiosis: A review in domestic animals Seyed Mostafa Razavi, Mohammad Sajjad Soltan, Kiarash Abbasian, Ali Karami, Saeed Nazifi Veterinary Parasitology.2024; 331: 110286. CrossRef DEVELOPMENT OF A QUANTITATIVE IMMUNOASSAY FOR SERUM HAPTOGLOBIN AS A PUTATIVE DISEASE MARKER IN THE SOUTHERN WHITE RHINOCEROS (CERATOTHERIUM SIMUM SIMUM) Henrik H. Petersen, Rikke Stenbak, Camilla Blaabjerg, Anne K.H. Krogh, Mads F. Bertelsen, Peter Buss, Peter M.H. Heegaard Journal of Zoo and Wildlife Medicine.2022;[Epub] CrossRef Assessment of the Immune Response of Clinically Infected Calves to Cryptosporidium parvum Infection Wael El-Deeb, Olimpia Iacob, Mahmoud Fayez, Ibrahim Elsohaby, Abdulrahman Alhaider, Hermine V. Mkrtchyan, Abdelazim Ibrahim, Naser Alhumam Agriculture.2022; 12(8): 1151. CrossRef Comparative study on plasma fibrinogen and ceruloplasmin concentrations during pregnancy and postpartum period in Bulgarian native goats I. Fasulkov, M. Karadaev, D. Zapryanova, T. Mircheva, N. Vasilev, F. Ceciliani BULGARIAN JOURNAL OF VETERINARY MEDICINE.2022; 25(4): 603. CrossRef Acute phase biomarkers of diseases in small ruminants: an overview P.T. Iliev, T.M. Georgieva BULGARIAN JOURNAL OF VETERINARY MEDICINE.2019; 22(1): 1. CrossRef Haptoglobin and serum amyloid A in goats with clinical form of caprine arthritis-encephalitis Michał Czopowicz, Olga Szaluś-Jordanow, Marcin Mickiewicz, Agata Moroz, Lucjan Witkowski, Iwona Markowska-Daniel, Tadeusz Stefaniak, Emilia Bagnicka, Jarosław Kaba Small Ruminant Research.2017; 156: 73. CrossRef Agreement between commercial assays for haptoglobin and serum amyloid A in goats Michał Czopowicz, Olga Szaluś-Jordanow, Marcin Mickiewicz, Agata Moroz, Lucjan Witkowski, Iwona Markowska-Daniel, Daria Reczyńska, Emilia Bagnicka, Jarosław Kaba Acta Veterinaria Scandinavica.2017;[Epub] CrossRef Effect of Ketoprofen on acute phase protein concentrations in goats undergoing castration Umit Karademir, Ibrahim Akin, Hasan Erdogan, Kerem Ural, Gamze Sevri Ekren Asici BMC Veterinary Research.2016;[Epub] CrossRef Dynamic Patterns of Systemic Innate Immunity and Inflammatory Associated Factors in Experimental Caprine Coccidiosis Shabnam Tadayon, Seyed Mostafa Razavi, Saeed Nazifi The Korean Journal of Parasitology.2016; 54(6): 719. CrossRef Intestinal pathogens, diarrhoea and acute phase proteins in naturally infected dairy calves Leena Seppä-Lassila, Toomas Orro, Brian Lassen, Riikka Lasonen, Tiina Autio, Sinikka Pelkonen, Timo Soveri Comparative Immunology, Microbiology and Infectious Diseases.2015; 41: 10. CrossRef Systemic acute phase proteins response in calves experimentally infected with Eimeria zuernii Brian Lassen, Berit Bangoura, Triin Lepik, Toomas Orro Veterinary Parasitology.2015; 212(3-4): 140. CrossRef Acute phase proteins and their use in the diagnosis of diseases in ruminants: a review C. Tothova, O. Nagy, G. Kovac Veterinární medicína.2014; 59(4): 163. CrossRef 10,614 View 94 Download Crossref