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Nilgun Ulfet Daldal	1 Article
Malondialdehyde, Glutathione, and Nitric Oxide Levels in Toxoplasma gondii Seropositive Patients Ulku Karaman, Tuncay ?elik, Tugba Raika Kiran, Cemil Colak, Nilgun Ulfet Daldal Korean J Parasitol 2008;46(4):293-295. Published online December 20, 2008 DOI: https://doi.org/10.3347/kjp.2008.46.4.293 Abstract PDF The aim of this study was to investigate the difference in the serum malondialdehyde (MDA), glutathione (GSH), and nitric oxide (NO) levels between normal and T. gondii-infected patients. To this end, MDA, GSH, and NO levels in the sera of 37 seropositive patients and 40 participants in the control group were evaluated. In Toxoplasma ELISA, IgG results of the patient group were 1,013.0 ± 543.8 in optical density (mean ± SD). A statistically significant difference was found between patients and the control group in terms of MDA, GSH, and NO levels. A decrease in GSH activity was detected, while MDA and NO levels increased significantly. Consequently, it is suggested that the use of antioxidant vitamins in addition to a parasite treatment shall prove useful. The high infection vs control ratio of MDA and NO levels probably suggests the occurrence as a mechanism of tissue damage in cases of chronic toxoplasmosis. Moreover, it is recommended that the patient levels of MDA, GSH, and NO should be evaluated in toxoplasmosis. Citations Citations to this article as recorded by Determination of Malondialdehyde, Nitric Oxide, Reduced Glutathione, Sialic Acid and Ceruloplasmin Levels in Sheep Liver Tissue With Hydatic Cyst Semistan Kızıltepe, Çağlar Okulmuş, Oğuz Merhan, Neriman Mor, Erdoğan Uzlu Kocatepe Veterinary Journal.2024; 17(1): 55. 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El Henawy Asian Pacific Journal of Tropical Medicine.2017; 10(3): 315. CrossRef More than an association: Latent toxoplasmosis might provoke a local oxidative stress that triggers the development of bipolar disorder Mohammed A. Afifi, Asif A. Jiman-Fatani, Mohammed W. Al-Rabia, Nabeel H. Al-Hussainy, Sherif El Saadany, Wael Mayah Journal of Microscopy and Ultrastructure.2017;[Epub] CrossRef Effect of Nigella sativa oil on experimental toxoplasmosis Rasha F. Mady, Wessam El-Hadidy, Samar Elachy Parasitology Research.2016; 115(1): 379. CrossRef Antiparasitic effects of oxymatrine and matrine against Toxoplasma gondii in vitro and in vivo Xiaochuan Zhang, Lili Jin, Zhe Cui, Changhao Zhang, Xue Wu, Hyun Park, Hongmei Quan, Chunmei Jin Experimental Parasitology.2016; 165: 95. CrossRef In Vitro and in Vivo Effects of Nitrofurantoin on Experimental Toxoplasmosis Seon-Ju Yeo, ChunMei Jin, SungYeon Kim, Hyun Park The Korean Journal of Parasitology.2016; 54(2): 155. CrossRef Role of oxidative stress in the pathophysiology ofToxoplasma gondiiinfection Gungor Cagdas Dincel, Hasan Tarik Atmaca International Journal of Immunopathology and Pharmacology.2016; 29(2): 226. CrossRef Caveolin-1 and Cancer Metabolism in the Tumor Microenvironment: Markers, Models, and Mechanisms Federica Sotgia, Ubaldo E. Martinez-Outschoorn, Anthony Howell, Richard G. Pestell, Stephanos Pavlides, Michael P. Lisanti Annual Review of Pathology: Mechanisms of Disease.2012; 7(1): 423. CrossRef Oxidative stress and tryptophan degradation pattern of acute Toxoplasma gondii infection in mice Ayse Basak Engin, Funda Dogruman-Al, Ugur Ercin, Bekir Celebi, Cahit Babur, Neslihan Bukan Parasitology Research.2012; 111(4): 1725. CrossRef Metabolic, immune, epigenetic, endocrine and phenotypic abnormalities found in individuals with autism spectrum disorders, Down syndrome and Alzheimer disease may be caused by congenital and/or acquired chronic cerebral toxoplasmosis Joseph Prandota Research in Autism Spectrum Disorders.2011; 5(1): 14. CrossRef Amelioration of glucose induced hemolysis of human erythrocytes by vitamin E Thankamani Marar Chemico-Biological Interactions.2011; 193(2): 149. CrossRef Stromal–epithelial metabolic coupling in cancer: Integrating autophagy and metabolism in the tumor microenvironment Ubaldo E. Martinez-Outschoorn, Stephanos Pavlides, Anthony Howell, Richard G. Pestell, Herbert B. Tanowitz, Federica Sotgia, Michael P. Lisanti The International Journal of Biochemistry & Cell Biology.2011; 43(7): 1045. 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