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Saeed Nazifi	3 Articles
Dynamic Patterns of Systemic Innate Immunity and Inflammatory Associated Factors in Experimental Caprine Coccidiosis Shabnam Tadayon, Seyed Mostafa Razavi, Saeed Nazifi Korean J Parasitol 2016;54(6):719-724. Published online December 31, 2016 DOI: https://doi.org/10.3347/kjp.2016.54.6.719 Abstract PDF The present study was designed to assess the dynamic patterns of pro-inflammatory cytokines, including IFN-γ, TNF-α, IL-4, IL-6, acute phase protein (α1-acid-glycoprotein, AGP), and an inflammation associated factor (adenosine deaminase; ADA) following experimental caprine coccidiosis. Ten kids aging from 2 to 4 months were infected orally with 5×10⁴ sporulated oocysts and 10 animals served as controls. Blood samples were collected in both groups before infection and at days 3, 7, 14, 21, 28, and 35 post-infection (PI), and the levels of above-mentioned factors were measured. IFN-γ, TNF-α, IL-4, IL-6, AGP, and ADA activities were significantly higher in infected animals from day 7 PI (P<0.05). In conclusion, the circulatory levels of most systemic inflammatory markers, including pro-inflammatory cytokines (IFN-γ, TNF-α, IL-4, IL-6), AGP, and ADA increased significantly starting from day 3 to day 7 PI in caprine coccidiosis. Citations Citations to this article as recorded by Isolation of a Novel Caprine Eimeria christenseni Strain (GC) in Canary Islands and Analysis of Parasitological, Clinical, and Pathological Findings on Experimentally Infected Goat Kids Emilio Barba, José Manuel Molina, Francisco Rodríguez, Otilia Ferrer, María Carmen Muñoz, Liliana M. R. Silva, María Cristina Del Río, José Adrián Molina, Anja Taubert, Carlos Hermosilla, Antonio Ruiz Animals.2025; 15(2): 139. CrossRef Acute phase response and oxidative stress in coccidiosis: A review in domestic animals Seyed Mostafa Razavi, Mohammad Sajjad Soltan, Kiarash Abbasian, Ali Karami, Saeed Nazifi Veterinary Parasitology.2024; 331: 110286. CrossRef The role of genetics in determining resistance to coccidiosis in goats a review of current research and future directions Tejswini Sontakke, Ashwini Biradar, Dinesh Nalage Molecular Biology Reports.2023; 50(7): 6171. CrossRef Effects of riboflavin and Bacillus subtilis on internal organ development and intestinal health of Ross 708 male broilers with or without coccidial challenge Sabin Poudel, Li Zhang, George T. Tabler, Jun Lin, Wei Zhai Poultry Science.2021; 100(4): 100973. CrossRef Oxidative stress linked to changes of cholinesterase and adenosine deaminase activities in experimentally infected chicken chicks with Eimeria spp Luiz Gustavo Griss, Gabriela M. Galli, Mateus Fracasso, Anielen D. Silva, Bruno Fortuoso, Maria Rosa C. Schetinger, Vera M. Morch, Marcel M. Boiago, Anderson Gris, Ricardo E. Mendes, Matheus D. Baldissera, Lenita M. Stefani, Aleksandro S. da Silva Parasitology International.2019; 71: 11. CrossRef 8,501 View 118 Download 5 Web of Science Crossref Changing Patterns of Acute Phase Proteins and Inflammatory Mediators in Experimental Caprine Coccidiosis Mohammad Hashemnia, Azizollah Khodakaram-Tafti, Seyed Mostafa Razavi, Saeed Nazifi Korean J Parasitol 2011;49(3):213-219. Published online September 30, 2011 DOI: https://doi.org/10.3347/kjp.2011.49.3.213 Abstract PDF This experiment was conducted to assess the changing patterns and relative values of acute phase proteins and inflammatory cytokines in experimental caprine coccidiosis. Eighteen newborn kids were allocated to 3 equal groups. Two groups, A and B, were inoculated with a single dose of 1×10³ and1×10⁵ sporulated oocysts of Eimeria arloingi, respectively. The third group, C, received distilled water as the control. Blood samples were collected from the jugular vein of each kid in both groups before inoculation and at days 7, 14, 21, 28, 35, and 42 post-inoculation (PI), and the levels of haptoglobin (Hp), serum amyloid A (SAA), TNF-α, and IFN-γ were measured. For histopathological examinations, 2 kids were selected from each group, euthanized, and necropsied on day 42 PI. Mean Hp concentrations in groups A and B (0.34 and 0.68 g/L) at day 7 PI were 3.2 and 6.3 times higher than the levels before inoculation. The mean SAA concentrations in groups A and B (25.6 and 83.5 ?g/ml) at day 7 PI were 4.2 and 13.7 times higher than the levels before inoculation. The magnitude and duration of the Hp and SAA responses correlated well with the inoculation doses and the severity of the clinical signs and diarrhea in kids. These results were consistent with the histopathological features, which showed advanced widespread lesions in group B. In both groups, significant correlations were observed for TNF-α and IFN-γ with SAA and Hp, respectively. In conclusion, Hp and SAA can be useful non-specific diagnostic indicators in caprine coccidiosis. Citations Citations to this article as recorded by Global prevalence of Eimeria species in goats: a systematic review and meta-analysis Endris A. Ali, Abdul Ghafar, Juan C. Angeles-Hernandez, Muhammad Yaseen, Charles G. Gauci, Ian Beveridge, Sandra Baxendell, Abdul Jabbar Frontiers in Veterinary Science.2025;[Epub] CrossRef First-generation merozoites of caprine Eimeria christenseni are capable to invade and egress primary host endothelial cells in vitro L.M.R. Silva, A. Ruiz, E. Barba, S. Lopéz-Osorio, J.A. Molina, J.M. Molina, A. Taubert, C. Hermosilla Frontiers in Veterinary Science.2025;[Epub] CrossRef Acute phase response and oxidative stress in coccidiosis: A review in domestic animals Seyed Mostafa Razavi, Mohammad Sajjad Soltan, Kiarash Abbasian, Ali Karami, Saeed Nazifi Veterinary Parasitology.2024; 331: 110286. CrossRef DEVELOPMENT OF A QUANTITATIVE IMMUNOASSAY FOR SERUM HAPTOGLOBIN AS A PUTATIVE DISEASE MARKER IN THE SOUTHERN WHITE RHINOCEROS (CERATOTHERIUM SIMUM SIMUM) Henrik H. Petersen, Rikke Stenbak, Camilla Blaabjerg, Anne K.H. Krogh, Mads F. Bertelsen, Peter Buss, Peter M.H. Heegaard Journal of Zoo and Wildlife Medicine.2022;[Epub] CrossRef Assessment of the Immune Response of Clinically Infected Calves to Cryptosporidium parvum Infection Wael El-Deeb, Olimpia Iacob, Mahmoud Fayez, Ibrahim Elsohaby, Abdulrahman Alhaider, Hermine V. Mkrtchyan, Abdelazim Ibrahim, Naser Alhumam Agriculture.2022; 12(8): 1151. CrossRef Comparative study on plasma fibrinogen and ceruloplasmin concentrations during pregnancy and postpartum period in Bulgarian native goats I. Fasulkov, M. Karadaev, D. Zapryanova, T. Mircheva, N. Vasilev, F. Ceciliani BULGARIAN JOURNAL OF VETERINARY MEDICINE.2022; 25(4): 603. CrossRef Acute phase biomarkers of diseases in small ruminants: an overview P.T. Iliev, T.M. Georgieva BULGARIAN JOURNAL OF VETERINARY MEDICINE.2019; 22(1): 1. CrossRef Haptoglobin and serum amyloid A in goats with clinical form of caprine arthritis-encephalitis Michał Czopowicz, Olga Szaluś-Jordanow, Marcin Mickiewicz, Agata Moroz, Lucjan Witkowski, Iwona Markowska-Daniel, Tadeusz Stefaniak, Emilia Bagnicka, Jarosław Kaba Small Ruminant Research.2017; 156: 73. CrossRef Agreement between commercial assays for haptoglobin and serum amyloid A in goats Michał Czopowicz, Olga Szaluś-Jordanow, Marcin Mickiewicz, Agata Moroz, Lucjan Witkowski, Iwona Markowska-Daniel, Daria Reczyńska, Emilia Bagnicka, Jarosław Kaba Acta Veterinaria Scandinavica.2017;[Epub] CrossRef Effect of Ketoprofen on acute phase protein concentrations in goats undergoing castration Umit Karademir, Ibrahim Akin, Hasan Erdogan, Kerem Ural, Gamze Sevri Ekren Asici BMC Veterinary Research.2016;[Epub] CrossRef Dynamic Patterns of Systemic Innate Immunity and Inflammatory Associated Factors in Experimental Caprine Coccidiosis Shabnam Tadayon, Seyed Mostafa Razavi, Saeed Nazifi The Korean Journal of Parasitology.2016; 54(6): 719. CrossRef Intestinal pathogens, diarrhoea and acute phase proteins in naturally infected dairy calves Leena Seppä-Lassila, Toomas Orro, Brian Lassen, Riikka Lasonen, Tiina Autio, Sinikka Pelkonen, Timo Soveri Comparative Immunology, Microbiology and Infectious Diseases.2015; 41: 10. CrossRef Systemic acute phase proteins response in calves experimentally infected with Eimeria zuernii Brian Lassen, Berit Bangoura, Triin Lepik, Toomas Orro Veterinary Parasitology.2015; 212(3-4): 140. CrossRef Acute phase proteins and their use in the diagnosis of diseases in ruminants: a review C. Tothova, O. Nagy, G. Kovac Veterinární medicína.2014; 59(4): 163. CrossRef 10,608 View 94 Download Crossref Hematological and Serum Biochemical Analyses in Experimental Caprine Besnoitiosis Saeed Nazifi, Ahmad Oryan, Fatemeh Namazi Korean J Parasitol 2011;49(2):133-138. Published online June 14, 2011 DOI: https://doi.org/10.3347/kjp.2011.49.2.133 Abstract PDF This study was undertaken to investigate the hematological and biochemical changes in experimentally infected goats with Besnoitia caprae from the time of infection till 360 days post-infection (PI). Six male goats were inoculated subcutaneously with 13×10⁷ bradyzoites of B. caprae, and blood samples were collected from the jugular vein. The total erythrocyte and total leukocyte counts, hematocrit value, and differential leukocyte counts were determined. Serum biochemical analysis, including the total protein, albumin, total globulin, cholesterol, triglyceride, chloride, testosterone, calcium (Ca²⁺), inorganic phosphorus, sodium (Na⁺), potassium (K⁺), iron (Fe²⁺), glucose, serum amyloid A (SAA), haptoglobin (Hp), fibrinogen, ceruloplasmin, aspartate aminotransferase, alanine aminotransferase, creatine kinase, lactate dehydrogenase, and alkaline phosphatase, was undertaken. Skin biopsy from the limbs were collected at weekly intervals and histologically examined for Besnoitia cysts. Cysts were present in the skin biopsies of the leg of the infected goats from day 28 PI. There were variations in hematological analyses, but no significant difference was seen. From day 30 to 360 PI, results showed that SAA, Hp, fibrinogen, and ceruloplasmin concentrations increased, whereas testosterone concentrations decreased. Infected goats exhibited decrease of albumin and increase of serum total protein and globulin concentrations. By contrast, there were no significant differences in the remained analyses concentrations. Citations Citations to this article as recorded by Effect of Ketoprofen on acute phase protein concentrations in goats undergoing castration Umit Karademir, Ibrahim Akin, Hasan Erdogan, Kerem Ural, Gamze Sevri Ekren Asici BMC Veterinary Research.2016;[Epub] CrossRef Natural Besnoitia besnoiti infections in cattle: hematological alterations and changes in serum chemistry and enzyme activities Martin C Langenmayer, Julia C Scharr, Carola Sauter-Louis, Gereon Schares, Nicole S Gollnick BMC Veterinary Research.2015; 11(1): 32. CrossRef 8,274 View 72 Download Crossref