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Yong Seok Lee	3 Articles
Expression and Characterization of α-Methylacyl CoA Racemase from Anisakis simplex Larvae Bong Jin Kim, Sun Mi Kim, Min Kyung Cho, Hak Sun Yu, Yong Seok Lee, Hee Jae Cha, Meesun Ock Korean J Parasitol 2012;50(2):165-171. Published online May 24, 2012 DOI: https://doi.org/10.3347/kjp.2012.50.2.165 Abstract PDF Larval excretory-secretory products of Anisakis simplex are known to cause allergic reactions in humans. A cDNA library of A. simplex 3rd-stage larvae (L3) was immunoscreened with polyclonal rabbit serum raised against A. simplex L3 excretory-secretory products to identify an antigen that elicits the immune response. One cDNA clone, designated as α-methylacyl CoA racemase (Amacr) contained a 1,412 bp cDNA transcript with a single open reading frame that encoded 418 amino acids. A. simplex Amacr showed a high degree of homology compared to Amacr orthologs from other species. Amacr mRNA was highly and constitutively expressed regardless of temperature (10-40℃) and time (24-48 hr). Immunohistochemical analysis revealed that Amacr was expressed mainly in the ventriculus of A. simplex larvae. The Amacr protein produced in large quantities from the ventriculus is probably responsible for many functions in the development and growth of A. simplex larvae. Citations Citations to this article as recorded by The mitochondrial genome ofAncylostoma tubaeformefrom cats in China X.L. Shi, Y.Q. Fu, A.Y. Abdullahi, M.W. Wang, F. Yang, X.G. Yu, W.D. Pan, X.X. Yan, J.X. Hang, P. Zhang, G.Q. Li Journal of Helminthology.2018; 92(1): 22. CrossRef α-Methylacyl-CoA racemase (AMACR): Metabolic enzyme, drug metabolizer and cancer marker P504S Matthew D. Lloyd, Maksims Yevglevskis, Guat Ling Lee, Pauline J. Wood, Michael D. Threadgill, Timothy J. Woodman Progress in Lipid Research.2013; 52(2): 220. CrossRef 10,300 View 51 Download Crossref Construction of EST Database for Comparative Gene Studies of Acanthamoeba Eun-Kyung Moon, Joung-Ok Kim, Ying-Hua Xuan, Young-Sun Yun, Se Won Kang, Yong Seok Lee, Tae-In Ahn, Yeon-Chul Hong, Dong-Il Chung, Hyun-Hee Kong Korean J Parasitol 2009;47(2):103-107. Published online May 26, 2009 DOI: https://doi.org/10.3347/kjp.2009.47.2.103 Abstract PDF The genus Acanthamoeba can cause severe infections such as granulomatous amebic encephalitis and amebic keratitis in humans. However, little genomic information of Acanthamoeba has been reported. Here, we constructed Acanthamoeba expressed sequence tags (EST) database (Acanthamoeba EST DB) derived from our 4 kinds of Acanthamoeba cDNA library. The Acanthamoeba EST DB contains 3,897 EST generated from amebae under various conditions of long term in vitro culture, mouse brain passage, or encystation, and downloaded data of Acanthamoeba from National Center for Biotechnology Information (NCBI) and Taxonomically Broad EST Database (TBestDB). The almost reported cDNA/genomic sequences of Acanthamoeba provide stand alone BLAST system with nucleotide (BLAST NT) and amino acid (BLAST AA) sequence database. In BLAST results, each gene links for the significant information including sequence data, gene orthology annotations, relevant references, and a BlastX result. This is the first attempt for construction of Acanthamoeba database with genes expressed in diverse conditions. These data were integrated into a database (http://www.amoeba.or.kr). Citations Citations to this article as recorded by High-efficiency transfection of Acanthamoeba castellanii using a cationic polymer Anaísa B. Moreno, Viktor Ek, Jens Eriksson, Mikael E. Sellin, Lionel Guy Cell Reports Methods.2026; 6(2): 101269. CrossRef Recombinant protein expression in Acanthamoeba castellanii Pooja Salunke, Kiran Kondabagil, Yogesh A. Karpe Frontiers in Bioengineering and Biotechnology.2025;[Epub] CrossRef Biological characteristics and pathogenicity of Acanthamoeba Yuehua Wang, Linzhe Jiang, Yitong Zhao, Xiaohong Ju, Le Wang, Liang Jin, Ryan D. Fine, Mingguang Li Frontiers in Microbiology.2023;[Epub] CrossRef Autophagy protein 12 plays an essential role in Acanthamoeba encystation So-Hee Kim, Eun-Kyung Moon, Yeonchul Hong, Dong-Il Chung, Hyun-Hee Kong Experimental Parasitology.2015; 159: 46. CrossRef Caspase-like proteins: Acanthamoeba castellanii metacaspase and Dictyostelium discoideum paracaspase, what are their functions? Entsar Saheb, Wendy Trzyna, John Bush Journal of Biosciences.2014; 39(5): 909. CrossRef Helminth parasites of fish and shellfish from the Santa Gilla Lagoon in southern Sardinia, Italy J. Culurgioni, A. Sabatini, R. De Murtas, S. Mattiucci, V. Figus Journal of Helminthology.2014; 88(04): 489. CrossRef Microarray and KOG analysis of Acanthamoeba healyi genes up-regulated by mouse-brain passage Eun-Kyung Moon, Ying-Hua Xuan, Hyun-Hee Kong Experimental Parasitology.2014; 143: 69. CrossRef Protein kinase C signaling molecules regulate encystation of Acanthamoeba Eun-Kyung Moon, Dong-Il Chung, Yeonchul Hong, Hyun-Hee Kong Experimental Parasitology.2012; 132(4): 524. CrossRef Microarray Analysis of Differentially Expressed Genes between Cysts and Trophozoites ofAcanthamoeba castellanii Eun-Kyung Moon, Ying-Hua Xuan, Dong-Il Chung, Yeonchul Hong, Hyun-Hee Kong The Korean Journal of Parasitology.2011; 49(4): 341. CrossRef Drug target identification, validation, characterisation and exploitation for treatment of Acanthamoeba (species) infections Craig W. Roberts, Fiona L. Henriquez Experimental Parasitology.2010; 126(1): 91. CrossRef Construction of Web-Based Database for Anisakis Research Yong-Seok Lee, Moon-Ki Baek, Yong-Hun Jo, Se-Won Kang, Jae-Bong Lee, Yeon-Soo Han, Hee-Jae Cha, Hak-Sun Yu, Mee-Sun Ock Journal of Life Science.2010; 20(3): 411. CrossRef 10,724 View 59 Download Crossref Expressed Sequence Tags of Trichinella spiralis Muscle Stage Larvae Hae Kyung Park, Seong Won Chang, Se Won Kang, Min Kyoung Cho, Sun Hee Choi, Yeon Chul Hong, Yong Seok Lee, Hae Jin Jeong, Hak Sun Yu Korean J Parasitol 2008;46(2):59-63. Published online June 20, 2008 DOI: https://doi.org/10.3347/kjp.2008.46.2.59 Abstract PDF In order to obtain greater insight into the relevant genomic expression patterns of Trichinella spiralis, 992 expressed sequence tags (ESTs) were collected from a cDNA library of T. spiralis muscle stage larvae and assembled into 60 clusters and 385 singletons. Of them, 445 (44.7%) ESTs were annotated to their homologous genes, and small fractions were matched to known genes of nematodes. The annotated ESTs were classified into 25 eukaryotic orthologous groups (KOG). Cytochrome C oxidase (34 clones) was found to be most frequent species. Citations Citations to this article as recorded by Characterisation of a high-frequency gene encoding a strongly antigenic cystatin-like protein from Trichinella spiralis at its early invasion stage Bin Tang, Mingyuan Liu, Libo Wang, Shenye Yu, Haining Shi, Pascal Boireau, Vasile Cozma, Xiuping Wu, Xiaolei Liu Parasites & Vectors.2015;[Epub] CrossRef Molecular characterization of 45kDa aspartic protease of Trichinella spiralis Jong Nam Park, Sang Kyun Park, Min Kyoung Cho, Mi-Kyung Park, Shin Ae Kang, Dong-Hee Kim, Hak Sun Yu Veterinary Parasitology.2012; 190(3-4): 510. CrossRef Protease-Activated Receptor 2 Is Involved in Th2 Responses againstTrichinella spiralisInfection Mi Kyung Park, Min Kyoung Cho, Shin Ae Kang, Hye-Kyung Park, Yun Seong Kim, Ki Uk Kim, Soon Cheol Ahn, Dong-Hee Kim, Hak Sun Yu The Korean Journal of Parasitology.2011; 49(3): 235. CrossRef Identification of host immune regulation candidate genes of Toxascaris leonina by expression sequenced tags (ESTs) analysis Min Kyoung Cho, Keun Hee Lee, Sun Joo Lee, Se Won Kang, Mee Sun Ock, Yeon Chul Hong, Yong Seok Lee, Hak Sun Yu Veterinary Parasitology.2009; 164(2-4): 242. CrossRef 9,236 View 86 Download Crossref