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Young-Ran Ha	4 Articles
Detection of Heparin in the Salivary Gland and Midgut of Aedes togoi Young-Ran Ha, So-Ra Oh, Eun-Seok Seo, Bo-Heum Kim, Dong-Kyu Lee, Sang-Joon Lee Korean J Parasitol 2014;52(2):183-188. Published online April 18, 2014 DOI: https://doi.org/10.3347/kjp.2014.52.2.183 Abstract PDF Mosquitoes secrete saliva that contains biological substances, including anticoagulants that counteract a host's hemostatic response and prevent blood clotting during blood feeding. This study aimed to detect heparin, an anticoagulant in Aedes togoi using an immunohistochemical detection method, in the salivary canal, salivary gland, and midgut of male and female mosquitoes. Comparisons showed that female mosquitoes contained higher concentrations of heparin than male mosquitoes. On average, the level of heparin was higher in blood-fed female mosquitoes than in non-blood-fed female mosquitoes. Heparin concentrations were higher in the midgut than in the salivary gland. This indicates presence of heparin in tissues of A. togoi. Citations Citations to this article as recorded by Unraveling the Molecular Mechanisms of Mosquito Salivary Proteins: New Frontiers in Disease Transmission and Control Jiayin Guo, Xiaoe He, Jianli Tao, Hui Sun, Jing Yang Biomolecules.2025; 15(1): 82. CrossRef The complexities of blood‐feeding patterns in mosquitoes and sandflies and the burden of disease: A minireview Fatma Bursali, Mustapha Touray Veterinary Medicine and Science.2024;[Epub] CrossRef Life History Metrics for Culex tarsalis (Diptera: Culicidae) and Culicoides sonorensis (Diptera: Ceratopogonidae) Are Not Impacted by Artificial Feeding on Defibrinated Versus EDTA-treated Blood Dustin A Swanson, Bethany L McGregor, William Reisen Journal of Medical Entomology.2023; 60(1): 224. CrossRef Mosquito as West Nile Virus Vector: Global Timeline of Detection, Characteristic, and Biology Jafar Ali Natasha, Abd Rahaman Yasmin, Reuben Sunil Kumar Sharma, Saulol Hamid Nur-Fazila, Md Isa Nur-Mahiza, Siti Suri Arshad, Hussni Omar Mohammed, Kiven Kumar, Shih Keng Loong, Mohd Kharip Shah Ahmad Khusaini Pertanika Journal of Tropical Agricultural Science.2023; 46(3): 1063. CrossRef A Review on Benzimidazole Heterocyclic Compounds: Synthesis and Their Medicinal Activity Applications Leqaa A. Mohammed, Mohammed Alwan Farhan, Safaa A. Dadoosh, Mustafa A. Alheety, Abdulwahhab H. Majeed, Ali Saadon Mahmood, Zaid H. Mahmoud SynOpen.2023; 07(04): 652. CrossRef Enzyme producing insect gut microbes: an unexplored biotechnological aspect Sandipan Banerjee, Tushar Kanti Maiti, Raj Narayan Roy Critical Reviews in Biotechnology.2022; 42(3): 384. CrossRef Biting Innovations of Mosquito-Based Biomaterials and Medical Devices Angela R. Dixon, Isabelle Vondra Materials.2022; 15(13): 4587. CrossRef Evaluation of cutaneous immune response in a controlled human in vivo model of mosquito bites David Guerrero, Hoa Thi My Vo, Chanthap Lon, Jennifer A. Bohl, Sreynik Nhik, Sophana Chea, Somnang Man, Sokunthea Sreng, Andrea R. Pacheco, Sokna Ly, Rathanak Sath, Sokchea Lay, Dorothée Missé, Rekol Huy, Rithea Leang, Hok Kry, Jesus G. Valenzuela, Fabian Nature Communications.2022;[Epub] CrossRef Gene drives in malaria control: what we need to know Reagan Mudziwapasi, Munyaradzi Christopher Changara, Abigarl Ndudzo, Tinotenda Kaseke, Farai Godobo, Floryn L. Mtemeli, Ryman Shoko, Fanuel Songwe, Sakhile Ndlovu, Sibonani Sandra Mlambo Biotechnology & Biotechnological Equipment.2021; 35(1): 1623. CrossRef Waveforms From Stylet Probing of the Mosquito Aedes aegypti (Diptera: Culicidae) Measured by AC–DC Electropenetrography Astri C Wayadande, Elaine A Backus, Bruce H Noden, Timothy Ebert, Julian Hillyer Journal of Medical Entomology.2020; 57(2): 353. CrossRef Sensitive Detection of Coralyne and Heparin Using a Singly Labeled Fluorescent Oligonucleotide Probe Xingxing Zhu, Miangjian Chen, Changbei Ma ChemistrySelect.2019; 4(19): 5686. CrossRef Potential pharmacological use of salivary compounds from hematophagous organisms Juan José Velásquez, José Ricardo Navarro-Vargas, Ligia Moncada Revista de la Facultad de Medicina.2017; 65(3): 501. CrossRef 10,641 View 88 Download 11 Web of Science Crossref Comparison of specific activity and cytopathic effects of purified 33 kDa serine proteinase from Acanthamoeba strains with different degree of virulence Won-Tae Kim, Hyun-Hee Kong, Young-Ran Ha, Yeon-Chul Hong, Hae Jin Jeong, Hak Sun Yu, Dong-Il Chung Korean J Parasitol 2006;44(4):321-330. Published online December 20, 2006 DOI: https://doi.org/10.3347/kjp.2006.44.4.321 Abstract PDF The pathogenic mechanism of granulomatous amebic encephalitis (GAE) and amebic keratitis (AK) by Acanthamoeba has yet to be clarified. Protease has been recognized to play an important role in the pathogenesis of GAE and AK. In the present study, we have compared specific activity and cytopathic effects (CPE) of purified 33 kDa serine proteinases from Acanthamoeba strains with different degree of virulence (A. healyi OC-3A, A. lugdunensis KA/E2, and A. castellanii Neff). Trophozoites of the 3 strains revealed different degrees of CPE on human corneal epithelial (HCE) cells. The effect was remarkably reduced by adding phenylmethylsulfonylfluoride (PMSF), a serine proteinase inhibitor. This result indicated that PMSF-susceptible proteinase is the main component causing cytopathy to HCE cells by Acanthamoeba. The purified 33 kDa serine proteinase showed strong activity toward HCE cells and extracellular matrix proteins. The purified proteinase from OC-3A, the most virulent strain, demonstrated the highest enzyme activity compared to KA/E2, an ocular isolate, and Neff, a soil isolate. Polyclonal antibodies against the purified 33 kDa serine proteinase inhibit almost completely the proteolytic activity of culture supernatant of Acanthamoeba. In line with these results, the 33 kDa serine proteinase is suggested to play an important role in pathogenesis and to be the main component of virulence factor of Acanthamoeba. Citations Citations to this article as recorded by Calcium ions in tap water may increase the adhesion ability of Acanthamoeba, potentially enhancing its cytopathic effects on corneal cells Yu-Jen Wang, Yao-Tsung Chang, Tsun-Hsien Hsiao, Chun-Hsien Chen, Chih-Ming Tsai, Jian-Ming Huang Parasite.2025; 32: 71. CrossRef Proteases of Acanthamoeba Behroz Mahdavi Poor, Jalil Rashedi, Vahid Asgharzadeh, Amirali Mirmazhary, Nazila Gheitarani Parasitology Research.2024;[Epub] CrossRef Characterization of novel extracellular proteases produced by Acanthamoeba castellanii after contact with human corneal epithelial cells and their relevance to pathogenesis Alvie Loufouma-Mbouaka, Tania Martín-Pérez, Martina Köhsler, Zeynep Danisman, Maya Schwarz, Rounik Mazumdar, Ascel Samba-Louaka, Julia Walochnik Parasites & Vectors.2024;[Epub] CrossRef Comparative cytotoxicity of Acanthamoeba castellanii-derived conditioned medium on human corneal epithelial and stromal cells Abdullah Alhazmi, Laura E. Sidney, Andy Hopkinson, Hany M. Elsheikha Acta Tropica.2024; 257: 107288. CrossRef Assessment of in vitro dynamics of pathogenic environmental Acanthamoeba T4 and T9 genotypes isolated from three recreational lakes in Klang Valley, Malaysia over the HaCaT cell monolayer Rohaya Abdul Halim, Hasseri Halim, Rosnani Hanim Mohd Hussain, Shafiq Aazmi, Naveed Ahmed Khan, Ruqaiyyah Siddiqui, Tengku Shahrul Anuar Journal of Water and Health.2024; 22(12): 2289. CrossRef Identification of an Antimicrobial Protease from Acanthamoeba via a Novel Zymogram Alvaro de Obeso Fernández del Valle, Luis Javier Melgoza-Ramírez, María Fernanda Esqueda Hernández, Alfonso David Rios-Pérez, Sutherland K. Maciver Processes.2023; 11(9): 2620. CrossRef Acanthamoeba Mannose and Laminin Binding Proteins Variation across Species and Genotypes Daniele Corsaro Microorganisms.2022; 10(11): 2162. CrossRef In Vitro Cytopathogenic Activities of Acanthamoeba T3 and T4 Genotypes on HeLa Cell Monolayer Rosnani Hanim Mohd Hussain, Mohamed Kamel Abdul Ghani, Naveed Ahmed Khan, Ruqaiyyah Siddiqui, Shafiq Aazmi, Hasseri Halim, Tengku Shahrul Anuar Pathogens.2022; 11(12): 1474. CrossRef Differential expression of Acanthamoeba castellanii proteins during amoebic keratitis in rats Ana Carolina Carvalho-Silva, Camila H. Coelho, Cecília Cirelli, Frederico Crepaldi, Isabela Aurora Rodrigues-Chagas, Cinthia Furst, Daniel Carvalho Pimenta, Juliano Simões de Toledo, Ana Paula Fernandes, Adriana Oliveira Costa Experimental Parasitology.2021; 221: 108060. CrossRef Peganum harmala Extract Has Antiamoebic Activity to Acanthamoeba triangularis Trophozoites and Changes Expression of Autophagy-Related Genes Rachasak Boonhok, Suthinee Sangkanu, Julalak Chuprom, Mayuna Srisuphanunt, Roghayeh Norouzi, Abolghasem Siyadatpanah, Farzaneh Mirzaei, Watcharapong Mitsuwan, Sueptrakool Wisessombat, Maria de Lourdes Pereira, Mohammed Rahmatullah, Polrat Wilairatana, Chr Pathogens.2021; 10(7): 842. CrossRef Extracellular protease profile of Acanthamoeba after prolonged axenic culture and after interaction with MDCK cells Cecília Cirelli, Elaine Isabela Soares Mesquita, Isabela Aurora Rodrigues Chagas, Cinthia Furst, Cynara Oliveira Possamai, Jonatas Santos Abrahão, Ludmila Karen dos Santos Silva, Marina Felipe Grossi, Carlos Alberto Tagliati, Adriana Oliveira Costa Parasitology Research.2020; 119(2): 659. CrossRef Busting biofilms: free-living amoebae disrupt preformed methicillin-resistant Staphylococcus aureus (MRSA) and Mycobacterium bovis biofilms Kevin H. Martin, Grace I. Borlee, William H. Wheat, Mary Jackson, Bradley R. Borlee Microbiology .2020; 166(8): 695. CrossRef Anti-amoebic potential of azole scaffolds and nanoparticles against pathogenic Acanthamoeba Shweta Walvekar, Ayaz Anwar, Areeba Anwar, Nanthini Sridewi, Mohammad Khalid, Yoon Yen Yow, Naveed Ahmed Khan Acta Tropica.2020; 211: 105618. CrossRef Identification and biochemical characterisation of Acanthamoeba castellanii cysteine protease 3 Zhixin Wang, Duo Wu, Hiroshi Tachibana, Meng Feng, Xun-jia Cheng Parasites & Vectors.2020;[Epub] CrossRef Extracellular vesicles and vesicle-free secretome of the protozoa Acanthamoeba castellanii under homeostasis and nutritional stress and their damaging potential to host cells Diego de Souza Gonçalves, Marina da Silva Ferreira, Susie Coutinho Liedke, Kamilla Xavier Gomes, Gabriel Afonso de Oliveira, Pedro Ernesto Lopes Leão, Gabriele Vargas Cesar, Sergio H. Seabra, Juliana Reis Cortines, Arturo Casadevall, Leonardo Nimrichter, Virulence.2018; 9(1): 818. CrossRef Characterization of extracellular proteases of Acanthamoeba genotype T4 isolated from different sources in Iran Behroz Mahdavi Poor, Abdolhossein Dalimi, Fatemeh Ghafarifar, Fariba Khoshzaban, Jalal Abdolalizadeh Parasitology Research.2017; 116(12): 3373. CrossRef Characterisation and expression analysis of trophozoite and cyst proteins of Acanthamoeba spp. isolated from Acanthamoeba keratitis (AK) patient Himansu Sekhar Behera, Gita Satpathy Molecular and Biochemical Parasitology.2016; 205(1-2): 29. CrossRef Microbial collagenases: challenges and prospects in production and potential applications in food and nutrition Gaurav Kumar Pal, Suresh PV RSC Advances.2016; 6(40): 33763. CrossRef Acanthamoeba culbertsoni: Electron‐Dense Granules in a Highly Virulent Clinical Isolate Bibiana Chávez‐Munguía, Lizbeth Salazar‐Villatoro, Maritza Omaña‐Molina, Martha Espinosa‐Cantellano, Elizabeth Ramírez‐Flores, Jacob Lorenzo‐Morales, Adolfo Martínez‐Palomo Journal of Eukaryotic Microbiology.2016; 63(6): 744. CrossRef Diversity, Structures, and Collagen-Degrading Mechanisms of Bacterial Collagenolytic Proteases Yu-Zhong Zhang, Li-Yuan Ran, Chun-Yang Li, Xiu-Lan Chen, F. E. Löffler Applied and Environmental Microbiology.2015; 81(18): 6098. CrossRef Acanthamoeba Protease Activity Promotes Allergic Airway Inflammation via Protease-Activated Receptor 2 Mi Kyung Park, Min Kyoung Cho, Shin Ae Kang, Hye-Kyung Park, Dong-Hee Kim, Hak Sun Yu, Venuprasad K. Poojary PLoS ONE.2014; 9(3): e92726. CrossRef Characterization of a Novel Subtilisin-like Protease Myroicolsin from Deep Sea Bacterium Myroides profundi D25 and Molecular Insight into Its Collagenolytic Mechanism Li-Yuan Ran, Hai-Nan Su, Ming-Yang Zhou, Lei Wang, Xiu-Lan Chen, Bin-Bin Xie, Xiao-Yan Song, Mei Shi, Qi-Long Qin, Xiuhua Pang, Bai-Cheng Zhou, Yu-Zhong Zhang, Xi-Ying Zhang Journal of Biological Chemistry.2014; 289(9): 6041. CrossRef Structural and mechanistic insights into collagen degradation by a bacterial collagenolytic serine protease in the subtilisin family Li‐Yuan Ran, Hai‐Nan Su, Guo‐Yan Zhao, Xiang Gao, Ming‐Yang Zhou, Peng Wang, Hui‐Lin Zhao, Bin‐Bin Xie, Xi‐Ying Zhang, Xiu‐Lan Chen, Bai‐Cheng Zhou, Yu‐Zhong Zhang Molecular Microbiology.2013; 90(5): 997. CrossRef Pathological characteristics of the different stages of Acanthamoeba keratitis Yuzhao Sun, Jing Hong, Pei Zhang, Rongmei Peng, Gege Xiao Histopathology.2013; 63(6): 862. CrossRef Proteases fromEntamoebaspp. and Pathogenic Free-Living Amoebae as Virulence Factors Jesús Serrano-Luna, Carolina Piña-Vázquez, Magda Reyes-López, Guillermo Ortiz-Estrada, Mireya de la Garza Journal of Tropical Medicine.2013; 2013: 1. CrossRef Acanthamoeba interactions with the blood–brain barrier under dynamic fluid flow James Edwards-Smallbone, Richard J. Pleass, Naveed A. Khan, Robin J. Flynn Experimental Parasitology.2012; 132(3): 367. CrossRef Host-Parasite Interaction: Parasite-Derived and -Induced Proteases That Degrade Human Extracellular Matrix Carolina Piña-Vázquez, Magda Reyes-López, Guillermo Ortíz-Estrada, Mireya de la Garza, Jesús Serrano-Luna Journal of Parasitology Research.2012; 2012: 1. CrossRef Serine protease activities in Leishmania (Leishmania) chagasi promastigotes Raquel Elisa da Silva-López, Tatiana Resende dos Santos, José Andrés Morgado-Díaz, Marcelo Neves Tanaka, Salvatore Giovanni de Simone Parasitology Research.2010; 107(5): 1151. CrossRef Pathogenesis of Acanthamoeba Keratitis Noorjahan Panjwani The Ocular Surface.2010; 8(2): 70. CrossRef Acanthamoeba culbertsoni Elicits Soluble Factors That Exert Anti-Microglial Cell Activity Jenica L. Harrison, Gabriela A. Ferreira, Erinn S. Raborn, Audrey D. Lafrenaye, Francine Marciano-Cabral, Guy A. Cabral Infection and Immunity.2010; 78(9): 4001. CrossRef Differential effects of α-helical and β-hairpin antimicrobial peptides against Acanthamoeba castellanii R. S. SACRAMENTO, R. M. MARTINS, A. MIRANDA, A. S. S. DOBROFF, S. DAFFRE, A. S. FORONDA, D. DE FREITAS, S. SCHENKMAN Parasitology.2009; 136(8): 813. CrossRef Elastase secretion in Acanthamoeba polyphaga Gabriela A. Ferreira, Ana C.M. Magliano, Elizabeth M.F. Pral, Silvia C. Alfieri Acta Tropica.2009; 112(2): 156. CrossRef Characterization of a Serine Proteinase Mediating Encystation of Acanthamoeba Eun-Kyung Moon, Dong-Il Chung, Yeon-Chul Hong, Hyun-Hee Kong Eukaryotic Cell.2008; 7(9): 1513. CrossRef Differentially expressed genes of Acanthamoeba castellanii during encystation Eun-Kyung Moon, Dong-Il Chung, Yeon-Chul Hong, Hyun-Hee Kong The Korean Journal of Parasitology.2007; 45(4): 283. CrossRef 11,583 View 89 Download Crossref Genetic diversity of Acanthamoeba isolates from ocean sediments Hua Liu, Young-Ran Ha, Sung-Tae Lee, Yean-Chul Hong, Hyun-Hee Kong, Dong-Il Chung Korean J Parasitol 2006;44(2):117-125. Published online June 20, 2006 DOI: https://doi.org/10.3347/kjp.2006.44.2.117 Abstract PDF Genetic diversity of 18 Acanthamoeba isolates from ocean sediments was evaluated by comparing mitochondrial (mt) DNA RFLP, 18S rDNA sequences and by examining their cytopathic effects on human corneal epithelial cells versus reference strains. All isolates belonged to morphologic group II. Total of 16 restriction phenotypes of mtDNA from 18 isolates demonstrated the genetic diversity of Acanthamoeba in ocean sediments. Phylogenetic analysis using 18s rDNA sequences revealed that the 18 isolates were distinct from morphological groups I and III. Fifteen isolates showed close relatedness with 17 clinical isolates and A. castellanii Castellani and formed a lineage equivalent to T4 genotype of Byers' group. Two reference strains from ocean sediment, A. hatchetti BH-2 and A. griffini S-7 clustered unequivocally with these 15 isolates. Diversity among isolates was also evident from their cytopathic effects on human corneal cells. This is the first time describing Acanthamoeba diversity in ocean sediments in Korea. Citations Citations to this article as recorded by Learning from the rDNA Operon: A Reanalysis of the Acanthamoeba palestinensis Group Daniele Corsaro Microorganisms.2024; 12(10): 2105. CrossRef The Status of Molecular Analyses of Isolates of Acanthamoeba Maintained by International Culture Collections Paul A. Fuerst Microorganisms.2023; 11(2): 295. CrossRef Detection of potentially pathogenic free-living amoebae from the Caspian Sea and hospital ward dust of teaching hospitals in Guilan, Iran Mohammad Reza Mahmoudi, Nozhat Zebardast, Frederick R. Masangkay, Panagiotis Karanis Journal of Water and Health.2021; 19(2): 278. CrossRef Isolates from ancient permafrost help to elucidate species boundaries in Acanthamoeba castellanii complex (Amoebozoa: Discosea) Stas Malavin, Lyubov Shmakova European Journal of Protistology.2020; 73: 125671. CrossRef Isolation and identification of free-living amoeba from the hot springs and beaches of the Caspian Sea Alireza Latifi, Mahboobeh Salami, Elham Kazemirad, Mohammad Soleimani Parasite Epidemiology and Control.2020; 10: e00151. CrossRef Update on Acanthamoeba phylogeny Daniele Corsaro Parasitology Research.2020; 119(10): 3327. CrossRef Nuclear Group I introns with homing endonuclease genes in Acanthamoeba genotype T4 Daniele Corsaro, Danielle Venditti European Journal of Protistology.2018; 66: 26. CrossRef Molecular detection of Acanthamoeba spp., Naegleria fowleri and Vermamoeba (Hartmannella) vermiformis as vectors for Legionella spp. in untreated and solar pasteurized harvested rainwater Penelope H. Dobrowsky, Sehaam Khan, Thomas E. Cloete, Wesaal Khan Parasites & Vectors.2016;[Epub] CrossRef Metagenomic characterization of viral communities in Goseong Bay, Korea Jinik Hwang, So Yun Park, Mirye Park, Sukchan Lee, Yeonhwa Jo, Won Kyong Cho, Taek-Kyun Lee Ocean Science Journal.2016; 51(4): 599. CrossRef Pandoraviruses: Amoeba Viruses with Genomes Up to 2.5 Mb Reaching That of Parasitic Eukaryotes Nadège Philippe, Matthieu Legendre, Gabriel Doutre, Yohann Couté, Olivier Poirot, Magali Lescot, Defne Arslan, Virginie Seltzer, Lionel Bertaux, Christophe Bruley, Jérome Garin, Jean-Michel Claverie, Chantal Abergel Science.2013; 341(6143): 281. CrossRef Mycobacterium gilvum Illustrates Size-Correlated Relationships between Mycobacteria and Acanthamoeba polyphaga Otmane Lamrabet, Michel Drancourt Applied and Environmental Microbiology.2013; 79(5): 1606. CrossRef Phylogenetic evidence for a new genotype of Acanthamoeba (Amoebozoa, Acanthamoebida) Daniele Corsaro, Danielle Venditti Parasitology Research.2010; 107(1): 233. CrossRef Barcoding Amoebae: Comparison of SSU, ITS and COI Genes as Tools for Molecular Identification of Naked Lobose Amoebae Elena Nassonova, Alexey Smirnov, Jose Fahrni, Jan Pawlowski Protist.2010; 161(1): 102. CrossRef Molecular Phylogeny of Acanthamoeba Hyun Hee Kong The Korean Journal of Parasitology.2009; 47(Suppl): S21. CrossRef Biodiversity of amoebae and amoebae‐resisting bacteria in a drinking water treatment plant Vincent Thomas, Jean‐François Loret, Michel Jousset, Gilbert Greub Environmental Microbiology.2008; 10(10): 2728. CrossRef Relationship between mycobacteria and amoebae: ecological and epidemiological concerns V. Thomas, G. McDonnell Letters in Applied Microbiology.2007; 45(4): 349. CrossRef 10,024 View 70 Download Crossref Purification and characterization of a 33 kDa serine protease from Acanthamoeba lugdunensis KA/E2 isolated from a Korean keratitis patient Hyo-Kyung Kim, Young-Ran Ha, Hak-Sun Yu, Hyun-Hee Kong, Dong-Il Chung Korean J Parasitol 2003;41(4):189-196. Published online December 20, 2003 DOI: https://doi.org/10.3347/kjp.2003.41.4.189 Abstract PDF In order to evaluate the possible roles of secretory proteases in the pathogenesis of amoebic keratitis, we purified and characterized a serine protease secreted by Acanthamoeba lugdunensis KA/E2, isolated from a Korean keratitis patient. The ammonium sulfate-precipitated culture supernatant of the isolate was purified by sequential chromatography on CM-Sepharose, Sephacryl S-200, and mono Q-anion exchange column. The purified 33 kDa protease had a pH optimum of 8.5 and a temperature optimum of 55℃. Phenylmethylsulfonylfluoride and 4-(2-Aminoethyl)-benzenesulfonyl-fluoride, both serine protease specific inhibitors, inhibited almost completely the activity of the 33 kDa protease whereas other classes of inhibitors did not affect its activity. The 33 kDa enzyme degraded various extracellular matrix proteins and serum proteins. Our results strongly suggest that the 33 kDa serine protease secreted from this keratopathogenic Acanthamoeba play important roles in the pathogenesis of amoebic keratitis, such as in corneal tissue invasion, immune evasion and nutrient uptake. Citations Citations to this article as recorded by Identification of an Antimicrobial Protease from Acanthamoeba via a Novel Zymogram Alvaro de Obeso Fernández del Valle, Luis Javier Melgoza-Ramírez, María Fernanda Esqueda Hernández, Alfonso David Rios-Pérez, Sutherland K. Maciver Processes.2023; 11(9): 2620. CrossRef The gene expression and proteomic profiling of Acanthamoeba isolates Chayan Sharma, Sumeeta Khurana, Alka Bhatia, Amit Arora, Amit Gupta Experimental Parasitology.2023; 255: 108630. CrossRef Comparative Surfaceome Analysis of Clonal Histomonas meleagridis Strains with Different Pathogenicity Reveals Strain-Dependent Profiles Marcelo de Jesus Ramires, Karin Hummel, Tamas Hatfaludi, Petra Riedl, Michael Hess, Ivana Bilic Microorganisms.2022; 10(10): 1884. CrossRef Host Invasion by Pathogenic Amoebae: Epithelial Disruption by Parasite Proteins Abigail Betanzos, Cecilia Bañuelos, Esther Orozco Genes.2019; 10(8): 618. CrossRef Acanthamoeba spp. un agente oportunista en infecciones humanas Martín Cabello-Vílchez Revista de Investigación de la Universidad Privada Norbert Wiener.2019; 4(1): 11. CrossRef Characterization of the Giardia intestinalis secretome during interaction with human intestinal epithelial cells: The impact on host cells Showgy Y. Ma’ayeh, Jingyi Liu, Dimitra Peirasmaki, Katarina Hörnaeus, Sara Bergström Lind, Manfred Grabherr, Jonas Bergquist, Staffan G. Svärd, Armando Jardim PLOS Neglected Tropical Diseases.2017; 11(12): e0006120. CrossRef Purification and Characterization of Extracellular Protease and Amylase Produced by the Bacterial Strain, Corynebacterium alkanolyticum ATH3 Isolated from Fish Gut Goutam Banerjee, Sandip Mukherjee, Shelley Bhattacharya, Arun K. Ray Arabian Journal for Science and Engineering.2016; 41(1): 9. CrossRef Microbial collagenases: challenges and prospects in production and potential applications in food and nutrition Gaurav Kumar Pal, Suresh PV RSC Advances.2016; 6(40): 33763. CrossRef Diversity, Structures, and Collagen-Degrading Mechanisms of Bacterial Collagenolytic Proteases Yu-Zhong Zhang, Li-Yuan Ran, Chun-Yang Li, Xiu-Lan Chen, F. E. Löffler Applied and Environmental Microbiology.2015; 81(18): 6098. CrossRef Microarray and KOG analysis of Acanthamoeba healyi genes up-regulated by mouse-brain passage Eun-Kyung Moon, Ying-Hua Xuan, Hyun-Hee Kong Experimental Parasitology.2014; 143: 69. CrossRef Characterization of a Novel Subtilisin-like Protease Myroicolsin from Deep Sea Bacterium Myroides profundi D25 and Molecular Insight into Its Collagenolytic Mechanism Li-Yuan Ran, Hai-Nan Su, Ming-Yang Zhou, Lei Wang, Xiu-Lan Chen, Bin-Bin Xie, Xiao-Yan Song, Mei Shi, Qi-Long Qin, Xiuhua Pang, Bai-Cheng Zhou, Yu-Zhong Zhang, Xi-Ying Zhang Journal of Biological Chemistry.2014; 289(9): 6041. CrossRef Structural and mechanistic insights into collagen degradation by a bacterial collagenolytic serine protease in the subtilisin family Li‐Yuan Ran, Hai‐Nan Su, Guo‐Yan Zhao, Xiang Gao, Ming‐Yang Zhou, Peng Wang, Hui‐Lin Zhao, Bin‐Bin Xie, Xi‐Ying Zhang, Xiu‐Lan Chen, Bai‐Cheng Zhou, Yu‐Zhong Zhang Molecular Microbiology.2013; 90(5): 997. CrossRef Proteases fromEntamoebaspp. and Pathogenic Free-Living Amoebae as Virulence Factors Jesús Serrano-Luna, Carolina Piña-Vázquez, Magda Reyes-López, Guillermo Ortiz-Estrada, Mireya de la Garza Journal of Tropical Medicine.2013; 2013: 1. CrossRef Host-Parasite Interaction: Parasite-Derived and -Induced Proteases That Degrade Human Extracellular Matrix Carolina Piña-Vázquez, Magda Reyes-López, Guillermo Ortíz-Estrada, Mireya de la Garza, Jesús Serrano-Luna Journal of Parasitology Research.2012; 2012: 1. CrossRef Distribution of Proteolytic Activity in the Different Protein Fractions of Tropical Shrimp Head Waste Raghu Ganugula, Rupsankar Chakrabarti, Krothapalli Raja Surya Sambasiva Rao Food Biotechnology.2008; 22(1): 18. CrossRef Protease activity in extracellular products secreted in vitro by trophozoites of Giardia duodenalis Thaís Batista de Carvalho, Érica Boarato David, Silvana Torossian Coradi, Semíramis Guimarães Parasitology Research.2008; 104(1): 185. CrossRef Comparison of specific activity and cytopathic effects of purified 33 kDa serine proteinase from Acanthamoeba strains with different degree of virulence Won-Tae Kim, Hyun-Hee Kong, Young-Ran Ha, Yeon-Chul Hong, Hae Jin Jeong, Hak Sun Yu, Dong-Il Chung The Korean Journal of Parasitology.2006; 44(4): 321. CrossRef Detection of a serine proteinase gene in Acanthamoeba genotype T6 (Amoebozoa: Lobosea) Marion Blaschitz, Martina Köhsler, Horst Aspöck, Julia Walochnik Experimental Parasitology.2006; 114(1): 26. CrossRef Intracellular Localization and Trafficking of Serine Proteinase AhSub and Cysteine Proteinase AhCP of Acanthamoeba healyi E.-K. Moon, S.-T. Lee, D.-I. Chung, H.-H. Kong Eukaryotic Cell.2006; 5(1): 125. CrossRef Étude de l’effet des oligomères procyanidoliques sur la fibrillogénèse de la cornée A.M. Robert, L. Robert, G. Renard Journal Français d'Ophtalmologie.2005; 28(10): 1017. CrossRef Expression of the nfa1 Gene Cloned from Pathogenic Naegleria fowleri in Nonpathogenic N. gruberi Enhances Cytotoxicity against CHO Target Cells In Vitro Seok-Ryoul Jeong, Sang-Chul Lee, Kyoung-Ju Song, Sun Park, Kyongmin Kim, Myung-Hee Kwon, Kyung-il Im, Ho-Joon Shin Infection and Immunity.2005; 73(7): 4098. CrossRef Extracellular proteases of Acanthamoeba castellanii (encephalitis isolate belonging to T1 genotype) contribute to increased permeability in an in vitro model of the human blood–brain barrier Selwa Alsam, James Sissons, Samantha Jayasekera, Naveed Ahmed Khan Journal of Infection.2005; 51(2): 150. CrossRef 8,897 View 87 Download Crossref