Thin layer immunoassay was carried out to demonstrate antibodies against Clonorchis sinensis in sera from clonorchiasis patients. Saline extract of adult worm was used as antigen. TIA technique was performed as described earlier by Elwing et al. (1976), but agarose was used instead of agar. The antibody titres of sera in 60 clonorchiasis cases were higher than that of 10 healthy and 10 amoebiasis cases, but not different comparing with that of 10 paragonimiasis cases. Antibody titres in clonorchiasis gave no differences according to the age, sex, EPG in feces, eosinophilia degree of blood, level of alkaline phosphatase and transaminase (SGOT, SGPT) in sera. It is suggested that, after evaluation, the TIA might supplement or be used as an alternative to other immunodiagnostic tests already in use for the diagnosis of clonorchiasis.
Citations
Citations to this article as recorded by
Comparison of TIA with ELISA for circulating antibody detection in clonorchiasis Yong Kie Lee, Jae Sook Ryu, Keun Tae Lee, Kyung Il Im The Korean Journal of Parasitology.1983; 21(2): 265. CrossRef
: A study of infestation patterns for larval trematodes from fresh-water fish and brackish-water fish was carried out during the period from June to October in 1982. They were collected by netting, fishing with rod and line, and using the bait of crushed oil cake in a transparent plastic bowls at the three localities, Daebon-dong, Kugil-dong, and Hoam-dong in the river Taechong, Kyungpook Province, Korea.
Five species of fresh-water fish, the crussian carp, Carassius carassius Linnaeus, the bullhead, Coreobagrus brevicorpus Mori, the fat minnow, Moroco oxycephalus (Bleeker), the flat bitterling, Paracheilognathus rhombea(Temminck et Schlegel), and the catfish, Parasilurus asotus (Linnaeus), and two kinds of brackish-water fish, the grey mullet, Mugil cephalus (Linnaeus) and the sweetfish, Plecoglossus altivelis (Temminck et Schlegel) were examined.
Four species of the metacercariae, Exorchis oviformis, Metacercari hasegawai, Metorchis orientalis and undetermined larvae were found. Of these, the encysted larvae of the human intestinal fluke, Metagonimus yokogawai, were found from three kinds of fresh-water fish, the crussian carp, the bullhead and the fat minnow and one species of brackish-water fish, the sweetfish and the infestation rates for the larvae varied appreciably from fish to fish. The intensity of infestation with the Metagonimus larvae in the three species of fresh-water fish as low, and the average number of the larvae per gram of flesh varied from 0.5 to 0.2. By comparison, the brackish-water fish was more heavily infested and the mean number of cysts per gram of flesh in Plecoglossus altivelis was 109.2. It was found that infection with Metagonimus yokogawai is caused by consuming raw fresh-water fish and brackish-water fish caught in the river Taechong, Kyungpook Province, Korea.
Citations
Citations to this article as recorded by
Infection characteristics of Metagonimus species (Digenea: Heterophyidae) metacercariae in fish from major rivers of Korea Woon-Mok Sohn Parasites, Hosts and Diseases.2024; 62(1): 1. CrossRef
A case of Diphyllobothrium latum infection with a brief review of diphyllobothriasis in the Republic of Korea Eun Bin Lee, Jung Hoon Song, Nam Seon Park, Byung Kook Kang, Hyung Suk Lee, Yoon Ju Han, Hyo-Jin Kim, Eun-Hee Shin, Jong-Yil Chai The Korean Journal of Parasitology.2007; 45(3): 219. CrossRef
Diphyllobothrium latum infection after eating domestic salmon flesh Kyung Won Lee, Hyo-Chung Suhk, Ki-Soo Pai, Ho-Jun Shin, Suk-Yul Jung, Eun-Taek Han, Jong-Yil Chai The Korean Journal of Parasitology.2001; 39(4): 319. CrossRef
Infection status of Pseudorasbora parva collected from the Sunam stream with metacercariae of Metorchis orientalis W M Sohn The Korean Journal of Parasitology.1991; 29(3): 311. CrossRef
Changing patterns of infection with digenetic larval trematodes from fresh-water fish in river Taewha, Kyongnam province Chong Yoon Joo The Korean Journal of Parasitology.1988; 26(4): 263. CrossRef
Studies on the Metagonimus fluke in the Daecheong reservoir and the upper stream of Geum river, Korea Chong Hwan Kim, Nam Man Kim, Chan Hyun Lee, Jin Suk Park The Korean Journal of Parasitology.1987; 25(1): 69. CrossRef
Epidemiological survey on Metagonimus yokogawai infection in the eastern coast area of Kangwon-province, Korea Yung Kyum Ahn, Pyung Rim Chung, Keun Tae Lee, Chin Thack Soh The Korean Journal of Parasitology.1987; 25(1): 59. CrossRef
Infestation of larval trematodes from fresh-water fish and brackish-water fish in River Hyungsan, Kyungpook Province, Korea Chong Yoon Joo The Korean Journal of Parasitology.1984; 22(1): 78. CrossRef
Epidemiological studies on Metagonimus yokogawai infection in Samcheok-gun, Kangwon-do, Korea Yung Kyum Ahn The Korean Journal of Parasitology.1984; 22(2): 161. CrossRef
Survey on encysted cercariae of trematodes from fresh-water fishes in Mangyeong riverside area Jae Ku Rhee, Ho Il Lee, Byeong Kirl Baek, Pyung Gil Kim The Korean Journal of Parasitology.1983; 21(2): 187. CrossRef
As a part of observation on the suitability as a second intermediate host of Clonorchis sinensis, various infection experiments were tried to Cyprinus carpio nudus. The results obtained were summarized as follows: The cercariae which attempted to contact with Cyprinus carpio nudus in the water were observed under the stereomicroscope. After contact, cercariae began to separate its tails from the bodies at 4 minutes increasingly, and then the number ranged to 80 percent at 13 minutes after the encounter. But very few cercariae could actually invade into the epidermis of the fish. When Cyprinus carpio nudus were exposed to a number of cercariae in the beaker, only a few cercariae could invade through the epidermis. Most of the invaded cercariae were killed before forming the cyst. Also rare encysted cercariae were found to be dead within 48 hours. Cyprinus carpio nudus were reared with Parafossarulus manchouricus shedding numerous cercariae in the indoor aquarium. When observed after 12 days, to determine the susceptibility, no metacercaria was found infected. Cyprinus carpio nudus were reared with Parafossarulus manchouricus shedding numerous cercariae in Kimhae lake for 2 months in summer of 1982, in order to check the natural infection. No metacercaria of Clonorchis sinensis was found from the fish. In the cases of control fish, Pseudorasbora parva, numerous cercariae were inspected on the course of invasion through epidermis of the fish under the stereomicroscope. And many metacercariae were also found from the fish whenever they were kept in beaker, indoor aquarium, or the lake for natural infection. The results suggested that Cyprinus carpio nudus might not be proper intermediate host of Clonorchis sinensis.
Citations
Citations to this article as recorded by
Susceptibility, metacercarial burden, and mortality of juvenile silver barb, common carp, mrigal, and tilapia following exposure to Haplorchis taichui Kulthida Kopolrat, Paiboon Sithithaworn, Smarn Tesana, Ross H. Andrews, Trevor N. Petney Parasitology Research.2015; 114(4): 1433. CrossRef
Clonorchiasis in Korea H J Rim The Korean Journal of Parasitology.1990; 28(Suppl): 63. CrossRef
The wormicidal substances of fresh water fishes on Clonorchis sinensis VII. The effect of linoleic acid and ethyl linoleate on parasite viability Jae Ku Rhee, Sang Bork Lee, Pyung Gil Kim The Korean Journal of Parasitology.1988; 26(3): 175. CrossRef
Experimental studies on the second intermediate hosts of Clonorchis sinensis IV. Observations on the fate of metacercariae of Clonorchis sinensis in the fish host, Cultriculus eigenmanni Jae Ku Rhee, Byeong Kirl Baek, Ho Il Lee The Korean Journal of Parasitology.1985; 23(1): 79. CrossRef
The wormicidal substance of fresh water fishes on Clonorchis sinensis V. Purification and chemical characterization of clonorchicidal substance from epidermal mucus of Cyprinus carpio Jae Ku Rhee, Sang Bork Lee, Byung Zun Ahn The Korean Journal of Parasitology.1984; 22(1): 127. CrossRef
The wormicidal substance of fresh water fishes on Clonorchis sinensis IV. Preliminary research on the wormicidal substance from mucus of Cyprinus carpio nudus Jae Ku Rhee, Pyung Gil Kim, Byeong Kirl Baek, Sang Bork Lee, Byung Zun Ahn The Korean Journal of Parasitology.1983; 21(1): 21. CrossRef
As a series of studies on the suitability as a second intermediate host of Clonorchis sinensis, the wormicidal effects of mucus from epidermis of Cyprinus carpio nudus were observed. The results obtained were summarized as follows: On the silica gel thin layer chromatography with the greenish yellow supernatant in acetone:benzene/10:90 as carrier, seven spots were observed in iodine chamber. The spot of Rf. 0.225 value among them disclosed the strongest wormicidal effect on the cercaria, the excysted metacercaria, and the adult of C. sinensis. Meanwhile, no seasonal variations were found in Rf. values and effect of the wormicidal fractions. The wormicidal materials in epidermal mucus of C. carpio nudus and Carassius carassius were compared in their effect, and the former was more effective killing substance than the latter. It seemed that C. carpio nudus could not be proper intermediate host of C.
sinensis according to results of the present study, in addition to our previous observation results.
Citations
Citations to this article as recorded by
The wormicidal substances of fresh water fishes on Clonorchis sinensis VII. The effect of linoleic acid and ethyl linoleate on parasite viability Jae Ku Rhee, Sang Bork Lee, Pyung Gil Kim The Korean Journal of Parasitology.1988; 26(3): 175. CrossRef
Experimental studies on the second intermediate hosts of Clonorchis sinensis IV. Observations on the fate of metacercariae of Clonorchis sinensis in the fish host, Cultriculus eigenmanni Jae Ku Rhee, Byeong Kirl Baek, Ho Il Lee The Korean Journal of Parasitology.1985; 23(1): 79. CrossRef
Seasonal Effects on Clonorchicidal Substances from Epidermal Mucus of Cyprinus carpio, Ophicephalus argus and Parasilurus asotus JK Rhee, SB Lee, BK Baek The Korean Journal of Parasitology.1984; 22(1): 135. CrossRef
The wormicidal substance of fresh water fishes on Clonorchis sinensis V. Purification and chemical characterization of clonorchicidal substance from epidermal mucus of Cyprinus carpio Jae Ku Rhee, Sang Bork Lee, Byung Zun Ahn The Korean Journal of Parasitology.1984; 22(1): 127. CrossRef
Serum IgE level and Clonorchis specific IgE in individuals with Clonorchis sinensis were determined by radioimmunosorbent(RIST) and radioallergosorbent technique(RAST) respectively. Highly significant elevations of serum IgE (P<0.001) and specific IgE antibodies (P<0.01) were observed in area from individuals with clonorchiasis.
The mean values of serum IgE in individuals with clonorchiasis and healthy individuals were 2,372 IU/ml and 364 IU/ml respectively and specific IgE antibodies of both groups were 52.0 and 4.4%. A close correlation(r=0.9451) between serum IgE level and specific IgE antibodies were observed and correlation (r=0.6056) between serum IgE and EPG and between specific IgE and EPG(r=0.5693) were also observed.
Citations
Citations to this article as recorded by
Allergen-like Molecules from Parasites Ju Yeong Kim, Myung-Hee Yi, Tai-Soon Yong Current Protein & Peptide Science.2020; 21(2): 186. CrossRef
Changing Patterns of Serum and Bile Antibodies in Re-infected Rats with Clonorchis sinensis Hongman Zhang, Byung-Suk Chung, Shunyu Li, Min-Ho Choi, Sung-Tae Hong The Korean Journal of Parasitology.2008; 46(1): 17. CrossRef
A Clonorchis sinensis-specific antigen that detects active human clonorchiasis S I Kim The Korean Journal of Parasitology.1998; 36(1): 37. CrossRef
Serum IgE levels in rats infected with Paragonimus westermani M H Shin, J S Ryu, D Y Min The Korean Journal of Parasitology.1991; 29(4): 397. CrossRef
Analysis of Clonorchis sinensis antigens and diagnosis of clonorchiasis using monoclonal antibodies T S Yong, K Im, P R Chung The Korean Journal of Parasitology.1991; 29(3): 293. CrossRef
The effects of antibodies and complement in macrophage-mediated cytotoxicity on metacercariae of the lung fluke, Paragonimus westermani D Y Min, M H Ahn, K M Kim, M H Leem, S Y Park The Korean Journal of Parasitology.1990; 28(2): 91. CrossRef
Purification of antigenic proteins of Paragonimus westermani and their applicability to experimental cat paragonimiasis Won Young Choi, Jae Eul Yoo, Ho Woo Nam, Hyung Rak Choi The Korean Journal of Parasitology.1986; 24(2): 177. CrossRef
Adult Clonorchis sinensis from infected human cases may have black pigment in their parenchyme. In present paper, the nature of the pigment was investigated. The pigment distributed in cytoplasm of parenchymal cells of the worms.
Histochemically the pigment was positive by periodic acid-Schiff, Ziehl-Neelsen, and lipofuscin stainings. The pigment particle contained many, various sized membrane structure as well as electron dense granules when observed by electron microscopy. Staining characteristics of the black pigment, together with electron microscopic findings, strongly indicated that the pigment was lipofuscin.
Citations
Citations to this article as recorded by
Clonorchis sinensis and Cholangiocarcinoma Eun-Min Kim, Sung-Tae Hong Journal of Korean Medical Science.2025;[Epub] CrossRef
Correlation between Discharged Worms and Fecal Egg Counts in Human Clonorchiasis Jae-Hwan Kim, Min-Ho Choi, Young Mee Bae, Jin-Kyoung Oh, Min Kyung Lim, Sung-Tae Hong, Akira Ito PLoS Neglected Tropical Diseases.2011; 5(10): e1339. CrossRef
Isozyme electrophoresis patterns of the liver fluke, Clonorchis sinensis from Kimhae, Korea and from Shenyang, China Gab-Man Park, Tai-Soon Yong, Kyung-il Im, Kyu-Je Lee The Korean Journal of Parasitology.2000; 38(1): 45. CrossRef
Clonorchiasis in Korea H J Rim The Korean Journal of Parasitology.1990; 28(Suppl): 63. CrossRef
The activity and distribution of aspartate aminotransferase (EC 2.6.1.1) and alanine aminotransferase (EC 2.6.1.2) in adult Fasciola hepatica have been studied. Fasciola hepatica was fractionated by differential centrifugation into nuclear, mitochondrial and cytosolic fractions. The activity of GOT and GPT was measured by the method of Reitman and Frankel. Isozyme patterns of those enzyme were also examined by DEAE-cellulose column chromatography. The results obtained were as follows: The activity of aspartate and alanine aminotransferase was about 0.55 unit and 0.92 unit per 1 g of Fasciola hepatica, respectively. The activity of those enzymes was relatively low compared with those in mammalian tissues. The distribution of aspartate aminotransferase in the subcellular organelles showed that 71 percent of the activity was in cytosolic, 24 percent in mitochondrial and 5 percent was in nuclear fraction. About 22 percent of the total alanine aminotransferase activity was found in the mitochondrial fraction, about 66 percent in the cytosolic fraction. Aspartate aminotransferase from cytosolic fraction was separated into two types of isozymes, whereas alanine aminotransferase from cytosolic fraction gave only one active peak on DEAE-cellulose column chromatography.
Citations
Citations to this article as recorded by
Intermediary metabolism in parasitic helminths D.P. McManus International Journal for Parasitology.1987; 17(1): 79. CrossRef
The distribution and properties of branched chain amino acid aminotransferase(EC 2.6.1.42) was investigated in adult Fasciola hepatica. Fasciola hepatica was fractionated by differential centrifugation into nuclear, mitochondrial and cytosolic fractions. The activity of branched chain amino acid aminotransferase was measured by the method of Ichihara and Koyama (1966) . Isozyme patterns of this enzyme was also examined by DEAE-cellulose column chromatography. The results obtained were as follows: The activity in homogenate was found to be 12.69 units/g wet tissue. The activity of this enzyme was relatively high compared with those in rat tissues. The distribution of branched chain amino acid aminotransferase in the subcellular organelles showed that 87.8 percent of the activity was in cytosolic, 10.9 percent in mitochondrial and 1.3 percent was in nuclear fraction.
Cytosolic fraction of Fasciola hepatica contained Enzyme I, but not Enzyme II and III, of branched chain amino acid aminotransferase. Enzyme I was eluted by 50 mM phosphate buffer from DEAE-cellulose column and catalyzed the transamination of all three branched chain amino acids. The Enzyme I was purified about 22-folds increase in specific activity after chromatography on DEAE-cellulose. The best substrate among three amino acids (leucine, isoleucine and valine) was L-isoleucine. The optimal temperature of Enzyme I was 45 C and the optimal pH was 8.2. The Km value for leucine of Enzyme I was 4.17 mM. The Km values for alpha-ketoglutarate and pyridoxal phosphate of Enzyme I were 0.41 mM and 4.76 x 10(-3) mM, respectively.
Citations
Citations to this article as recorded by
Intermediary metabolism in parasitic helminths D.P. McManus International Journal for Parasitology.1987; 17(1): 79. CrossRef
The intestinal lesions were studied in dog metagonimiasis by reinfection. The metacercariae of M. yokogawai were collected from naturally infected sweetfish. A total of twenty dogs were divided into three groups; control, primary infection and reinfection groups. The 18 dogs were infected with 10,000 metacercariae; the 5 dogs in primary infection group were killed at the 5 days in 1 week, 4 weeks, 6 weeks after the infection. The remaining 13 dogs were kept for nine weeks, and challenged again with 5,000 metacercaricae.
The reinfected dogs were killed at the 1 day, 3 days, 5 days and 1 week, 2 weeks, 4 weeks, 6 weeks, 8 weeks respectively.
The chronologic changes of the intestinal lesions in both groups, the worm recovery rate, and distribution patten were examined by gross observation, light and scanning electron microscopies. From the results, it was inferred that the so-called spontaneous and/or self cure phenomena were of negligible importance in metagonimiasis in dogs. In the chronologic observations of pathologic process in intestine, it was also suggested that the host immunity tend to recover the intestinal integrity. And early invasion of young worm to the Lieberkuhn's crypt was considered as the primary cause of lesions of vill(Abstract is summarized again.)
Citations
Citations to this article as recorded by
Digenean Holostephanus (Trematoda: Digenea: Cyathocotylidae) metacercariae in common carp (Cyprinus carpio Linnaeus, 1758) muscle: zoonotic potential and sensitivity to physico-chemical treatments D. Sándor, M. Gyöngy, K. Nyeste, I. Czeglédi, C. Székely, K. Buchmann, G. Cech Journal of Helminthology.2020;[Epub] CrossRef
Fishborne zoonotic heterophyid infections: An update Jong-Yil Chai, Bong-Kwang Jung Food and Waterborne Parasitology.2017; 8-9: 33. CrossRef
Population dynamics and host reactions in young foxes following experimental infection with the minute intestinal fluke, Haplorchis pumilio Sofie Nissen, Stig Milan Thamsborg, Per Walther Kania, Páll S Leifsson, Anders Dalsgaard, Maria Vang Johansen Parasites & Vectors.2013;[Epub] CrossRef
Experimental infection with the small intestinal trematode, Haplorchis pumilio, in young dogs Sofie Nissen, Lan Anh Thi Nguyen, Anders Dalsgaard, Stig Milan Thamsborg, Maria Vang Johansen Veterinary Parasitology.2013; 191(1-2): 138. CrossRef
Foodborne Intestinal Flukes in Southeast Asia Jong-Yil Chai, Eun-Hee Shin, Soon-Hyung Lee, Han-Jong Rim The Korean Journal of Parasitology.2009; 47(Suppl): S69. CrossRef
Preliminary observations on infection of brackish and fresh water fish by heterophyid encysted metacercariae in Egypt Hany M. Elsheikha, Attef M. Elshazly Parasitology Research.2008; 103(4): 971. CrossRef
Host-dependent variations in the seasonal prevalence and intensity of heterophyid encysted metacercariae (Digenea: Heterophyidea) in brackish water fish in Egypt Hany M. Elsheikha, Attef M. Elshazly Veterinary Parasitology.2008; 153(1-2): 65. CrossRef
Heterophyid metacercarial infections in brackish water fishes from Jinju-man (Bay), Kyongsangnam-do, Korea Do Gyun Kim, Tong-Soo Kim, Shin-Hyeong Cho, Hyeon-Je Song, Woon-Mok Sohn The Korean Journal of Parasitology.2006; 44(1): 7. CrossRef
Food-borne intestinal trematode infections in the Republic of Korea Jong-Yil Chai, Soon-Hyung Lee Parasitology International.2002; 51(2): 129. CrossRef
Intestinal histopathology and in situ postures of Gymnophalloides seoi in experimentally infected mice Jong-Yil Chai, Hong-Soon Lee, Sung-Jong Hong, Jae Hyung Yoo, Sang-Mee Guk, Min Seo, Min-Ho Choi, Soon-Hyung Lee The Korean Journal of Parasitology.2001; 39(1): 31. CrossRef
A review of Gymnophalloides seoi (Digenea: Gymnophallidae) and human infections in the Republic of Korea Soon-Hyung Lee, Jong-Yil Chai The Korean Journal of Parasitology.2001; 39(2): 85. CrossRef
Intestinal mastocytosis and goblet cell hyperplasia in BALB/c and C3H mice infected with Neodiplostomum seoulense J Y Chai, T K Kim, W H Cho, M Seo, J Kook, S M Guk, S H Lee The Korean Journal of Parasitology.1998; 36(2): 109. CrossRef
Plagiorchis muris: recovery, growth and development in albino rats S.J. Hong, J.H. Ahn, H.C. Woo Journal of Helminthology.1998; 72(3): 251. CrossRef
Invasion of Metagonimus yokogawai into the submucosal layer of the small intestine of immunosuppressed mice J Y Chai, J Kim, S H Lee The Korean Journal of Parasitology.1995; 33(4): 313. CrossRef
The effect of reinfection with Neodiplostomum seoulensis on the histopathology and activities of brush border membrane bound enzymes in the rat small intestine J R Yu, S T Hong, J Y Chai, S H Lee The Korean Journal of Parasitology.1995; 33(1): 37. CrossRef
Chronological observation on intestinal histopathology and intraepithelial lymphocytes in the intestine of rats infected with Metagonimus yokogawai J Y Chai, T Y Yun, J Kim, S Huh, M H Choi, S H Lee The Korean Journal of Parasitology.1994; 32(4): 215. CrossRef
Mucosal mast cell responses to experimental Metagonimus yokogawai infection in rats J Y Chai, T H Kim, W G Kho, S W Chung, S T Hong, S H Lee The Korean Journal of Parasitology.1993; 31(2): 129. CrossRef
Worm recovery rate and small intestinal lesions of albino rats coinfected with Fibricola seoulensis and Metagonimus yokogawai S J Hong, H C Woo, S Y Lee, J H Ahn, C K Park, J Y Chai, S H Lee The Korean Journal of Parasitology.1993; 31(2): 109. CrossRef
Antigenic localities in the tissues of Metagonimus yokogawai observed by immunogoldlabeling method H Ahn, H J Rim, S J Kim The Korean Journal of Parasitology.1991; 29(3): 245. CrossRef
Activities of brush border membrane bound enzymes of the small intestine in Metagonimus yokogawai infection in mice S T Hong, J R Yu, N H Myong, J Y Chai, S H Lee The Korean Journal of Parasitology.1991; 29(1): 9. CrossRef
Recovery rate, growth and development of Heterophyopsis continua in experimental chicks S J Hong, S H Lee, J Y Chai, B S Seo The Korean Journal of Parasitology.1990; 28(1): 53. CrossRef
Chronological observation of intestinal lesions of rats experimentally infected with Echinostoma hortense S H Lee, T Y Noh, W M Sohn, W G Kho, S T Hong, J Y Chai The Korean Journal of Parasitology.1990; 28(1): 45. CrossRef
Observation of mucosal pathology after praziquantel treatment in experimental Fibricola seoulensis infection in rats S H Lee, B I Kim, S T Hong, W M Sohn, J Y Chai The Korean Journal of Parasitology.1989; 27(1): 35. CrossRef
Specific IgG antibody responses in experimental cat metagonimiasis Seung Yull Cho, Suk Il Kim, Shin Yong Kang The Korean Journal of Parasitology.1987; 25(2): 149. CrossRef
Studies on the Metagonimus fluke in the Daecheong reservoir and the upper stream of Geum river, Korea Chong Hwan Kim, Nam Man Kim, Chan Hyun Lee, Jin Suk Park The Korean Journal of Parasitology.1987; 25(1): 69. CrossRef
A histopathological study on the intestine of mice and rats experimentally infected by Fibricola Seoulensis Soon Hyung Lee, Byong Hoon Yoo, Sung Tae Hong, Jong Yil Chai, Byong Seol Seo, Je Geun Chi The Korean Journal of Parasitology.1985; 23(1): 58. CrossRef
Studies on the intestinal fluke, Metagonimus yokogawai Katsurada, 1912 in Korea Geographical distribution of sweetfish and infection status with Metagonimus metacercaria in south-eastern area of Korea Chul Yong Song, Soon Hyung Lee, Sang Rin Jeon The Korean Journal of Parasitology.1985; 23(1): 123. CrossRef
Study on Metagonimus yokogawai(Katsurada, 1912) in Korea VII. Susceptibility of various strains of mice to Metagonimus infection and effect of Prednisolone Jong Yil Chai, Byong Seol Seo, Soon Hyung Lee The Korean Journal of Parasitology.1984; 22(2): 153. CrossRef
Study on Metagonimus yokogawai(Katsurada, 1912) in Korea VII. Electron microscopic observation on the tegumental structure Soon Hyung Lee, Byong Seol Seo, Jong Yil Chai, Sung Jong Hong The Korean Journal of Parasitology.1984; 22(1): 1. CrossRef
An electron microscopic study was performed to know the basic tegumental structure of Cysticercus cellulosae. The scolex and bladder portions of cysticerci (human and porcine strains) were prepared for transmission and scanning electron microscopy by conventional procedures. In general, the tegument of C. cellulosae showed the basic ultrastructure of cestode tegument on electron micrographs.
The teguments of both scolex and bladder portions consisted of such components i.e., an outer vesicular layer with numerous microtriches and inner fibrous layer. Below the fibrous layer, there were layers of muscle bundles and tegumental cells. The microtriches which covered the surface of cysticercus revealed two distinctly different shapes. The characteristic bladder-like, elongated pyramid shaped 'tetrahedral form' was observed on the surface of the scolex portion, whereas the elongated cylindrical 'filamentous form' was distributed on the surface of bladder portion. In spite of the difference of isolated host and location, the cysticerci showed the same result. But dimensional variations of the tegument according to topography of the worm were observed. The possibility of application in making differential diagnosis from other larval cestodes and possible functions of this larval tegument were discussed.
Citations
Citations to this article as recorded by
Early morphogenesis in the platyhelminthes with special reference to egg development and development of cestode larvae M.D.B. Burt International Journal for Parasitology.1987; 17(1): 241. CrossRef
A survey on the infection status of sparganum and Gnathostoma in frogs was carried out in 11 areas in Gyeongsangnam-do and Cheonlanam-do province, a southern part of Korea. Among 626 frogs examined, 4 percent were infected with sparganum, but none with Gnathostoma. The infection rates of sparganum were variable according to the areas.
Those from Kimhae, Sunchun, Jinhae, Sachun, Kosung, Keoje, and Hadong were 16 percent, 9.1 percent, 9.1 percent, 4.1 percent, 2 percent, 2 percent, and 1.5 percent respectively, but frogs from Hapchun, KwangJu, Namwon and Sanchung were not found infected. Rana nigromaculata was the only species infected with sparganum. Rana rugosa and Bombina orientalis were not infected. Sparganum was mainly found in the legs and the trunk of frog. About 92.5 percent of worms were detected in the femoral intermuscular connective tissue.
Number per infected frog was in range of one to five, and 2.8 percent of frogs were infected by only one worm. The heavier the frog weight, the higher the infection rate of sparganum. In frogs of 51-60 grams, 28.6 percent were infected.
Citations
Citations to this article as recorded by
Larval Gnathostomes and Spargana in Chinese Edible Frogs, Hoplobatrachus rugulosus, from Myanmar: Potential Risk of Human Infection Jong-Yil Chai, Bong-Kwang Jung, Jin-Youp Ryu, Hyun-Seung Kim, Sung-Jong Hong, Thi Thi Htoon, Htay Htay Tin, Byoung-Kuk Na, Woon-Mok Sohn The Korean Journal of Parasitology.2020; 58(4): 467. CrossRef
Human Sparganosis in Korea Jeong-Geun Kim, Chun-Seob Ahn, Woon-Mok Sohn, Yukifumi Nawa, Yoon Kong Journal of Korean Medical Science.2018;[Epub] CrossRef
Spargana in a Weasel, Mustela sibirica manchurica, and a Wild Boar, Sus scrofa, from Gangwon-do, Korea Seung-Ha Lee, Eun-Yoon Choe, Hyun-Duk Shin, Min Seo The Korean Journal of Parasitology.2013; 51(3): 379. CrossRef
Surface Ultrastructure of the Advanced Third-stage Larvae of Gnathostoma nipponicum E-T. Han, J-H. Lee, S-Y. Choi, J-H. Park, E-H. Shin, J-Y. Chai Journal of Parasitology.2003; 89(6): 1245. CrossRef
The first discovery of larval Gnathostoma hispidum (Nematoda: Gnathostomidae) from a snake host, Agkistrodon brevicaudus W M Sohn, S H Lee The Korean Journal of Parasitology.1998; 36(2): 81. CrossRef
Identification of larval Gnathostoma obtained from imported Chinese loaches W M Sohn, S H Lee The Korean Journal of Parasitology.1996; 34(3): 161. CrossRef
Larval Gnathostoma nipponicum found in the imported Chinese loaches W M Sohn, W G Kho, S H Lee The Korean Journal of Parasitology.1993; 31(4): 347. CrossRef
The fate of spargana inoculated into the cat brain and sequential changes of anti-sparganum IgG antibody levels in the cerebrospinal fluid K C Wang, S Huh, S T Hong, J Y Chai, K S Choi, S H Lee The Korean Journal of Parasitology.1990; 28(1): 1. CrossRef
Experimental life history of Spirometra erinacei S H Lee, J S We, W M Sohn, S T Hong, J Y Chai The Korean Journal of Parasitology.1990; 28(3): 161. CrossRef
Cestode infections in Korea D Y Min The Korean Journal of Parasitology.1990; 28(Suppl): 123. CrossRef
Two cases of human infection by adult of Spirometra erinacei Soon Hyung Lee, Jong Yil Chai, Byong Seol Seo, Seung Yull Cho The Korean Journal of Parasitology.1984; 22(1): 66. CrossRef
An imported case of Kala-azar in a 26-year-old Korean man is reported. The diagnosis was made by liver needle biopsy.
Amastigotes were seen in Kupffer cells under light microscope, and their characteristic ultrastructural features were recognized under the electron microscope. This case represents an imported disease from Saudi Arabia where the patient spent one year as a construction worker, 8 months before the onset of the disease. This report also signifies the second description of Kala-azar in Korea, and the first case of Kala-azar imported from Saudi Arabia. This patient was successfully treated with sodium antimony gluconate (Pentostam), and follow up liver biopsy showed focal fibrous scar and otherwise normal liver without demonstrable organism.
Citations
Citations to this article as recorded by
Imported parasitic diseases in the Republic of Korea: status and issues Jong-Yil Chai Journal of the Korean Medical Association.2025; 68(1): 52. CrossRef
Review of Successful Control of Parasitic Infections in Korea Sung-Tae Hong, Tai-Soon Yong Infection & Chemotherapy.2020; 52(3): 427. CrossRef
Who Neglects Neglected Tropical Diseases? - Korean Perspective Min-Ho Choi, Jae-Ran Yu, Sung-Tae Hong Journal of Korean Medical Science.2015; 30(Suppl 2): S122. CrossRef
International Travel and Imported Parasitic Diseases Kyoung-Hwan Joo Hanyang Medical Reviews.2010; 30(3): 156. CrossRef
Imported Parasitic Diseases in Korea Myoung-Hee Ahn Infection and Chemotherapy.2010; 42(5): 271. CrossRef
Traveling and Imported Parasitic Diseases Myoung-Hee Ahn Journal of the Korean Medical Association.2007; 50(11): 993. CrossRef
Human infections by Heterophyes heterophyes and H. dispar imported from Saudi Arabia Jong Yil Chai, Byong Seol Seo, Soon Hyung Lee, Sung Jong Hong, Woon Mok Sohn The Korean Journal of Parasitology.1986; 24(1): 82. CrossRef
Two cases of imported cutaneous leishmaniasis in Korea Tae Young Yun, Hee Chul Eun, Yoo Shin Lee, Je Geun Chi, Eui Keun Ham, Sung Tae Hong, Soon Hyung Lee The Korean Journal of Parasitology.1985; 23(2): 327. CrossRef
Mebendazole was tested for its efficacy in individual treatment and mass control of Trichuris trichiura infection in Korea. The results were as follows: The efficacy of mebendazole in 430 cases 3 weeks after treatment with mebendazole(100-1,200 mg) was not so satisfactory (15.0-64.0 and 24.6-95.2% in cure and egg reduction rates respectively). But it was observed that the higher the total dose of the drug the better the efficacy. The egg positive rate of the inhabitants in mass control programme by 600 mg mebendazole decreased form 40.0 to 5.6 % during one year, May 1982-May 1983, by repeated blanket mass chemotherapy every 3 months (in conventional regimen), while the decrease was less marked or unrecognizable in 3-month (signle or two divided doses), 6-month, 12-month interval and placebo control groups. From the results, it was concluded that, although mebendazole was not highly effective in individual treatment of T. trichiura infection, it was fairly useful in mass cotrol, by repeated mass chemotherapy every 3 months.
Citations
Citations to this article as recorded by
Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update Jong-Yil Chai, Bong-Kwang Jung, Sung-Jong Hong The Korean Journal of Parasitology.2021; 59(3): 189. CrossRef
A new endemic focus of Heterophyes nocens, Pygidiopsis summa, and other intestinal flukes in a coastal area of Muan-gun, Chollanam-do J Y Chai, I M Kim, M Seo, S M Guk, J L Kim, W M Sohn, S H Lee The Korean Journal of Parasitology.1997; 35(4): 233. CrossRef
Intestinal trematodes of humans in Korea: Metagonimus, heterophyids and echinostomes J Y Chai, S H Lee The Korean Journal of Parasitology.1990; 28(Suppl): s103. CrossRef
A total of 2,026 leprosy patients of the National Sorokdo Hospital was examined their intestinal parasites by cellophane thick smear method in January 1983. The egg positive cases of Taenia spp. were treated with bithionol and the segments of Taenia were collected for species identification. The results were as follows: Total egg positive rate of any kind helminth was 78.2 percent and cumulative total was 85.2 percent. The egg positive rate for each helminth was as follow; Taenia spp. 3.4 percent, Ascaris lumbricoides 4.5 percent, Trichuris trichiura 72.l percent, Clonorchis sinensis 2.8 percent and other 0.05 percent. A total of 66 Taenia egg positive cases was treated; out of them proglottids of Taenia were collected from 26 cases. All of the collected worms were identified as T. saginata. The results revealed significantly high egg positive rate of T. trichiura. However, A. lumbricoides was found to be controlled considerably by repeated chemotherapy during past 3 years. If chemotherapeutic agent is replaced with oxantel-pyrantel tablet, better result is expected. No clue was found for prevalence of T. solium from both human and the pig in the island.
Citations
Citations to this article as recorded by
Sustainable Conservation of a Difficult Heritage in South Korea: Mapping the Conservation Resources of Sorok-do Island, Hansen’s Disease Site Seong-Gon Jang, Hyun Kyung Lee, Dong-Jin Kang Sustainability.2020; 12(17): 6834. CrossRef
Human Taeniasis in the Republic of Korea: Hidden or Gone? Jong-Yil Chai The Korean Journal of Parasitology.2013; 51(1): 9. CrossRef
Epidemiological understanding of Taenia tapeworm infections with special reference to Taenia asiatica in Korea Keeseon S. Eom, Han-Jong Rim The Korean Journal of Parasitology.2001; 39(4): 267. CrossRef
Mite infestation rate of pet dogs with ear dermatoses G S Park, J S Park, B K Cho, W K Lee, J H Cho The Korean Journal of Parasitology.1996; 34(2): 143. CrossRef
Natural infections of Asian Taenia saginata metacestodes in the livers of Korean domestic pigs K S Eom, H J Rim The Korean Journal of Parasitology.1992; 30(1): 15. CrossRef
Intestinal parasite infections among inhabitants in two islands of Tongyeong-gun, Kyeongsangnam-do S J Hong, H C Woo, J H Han, Y K Seong The Korean Journal of Parasitology.1990; 28(1): 63. CrossRef
A survey on vegetables, which consisted of lettuce (Lactuca sativa), young radish (Raphanus sapivus), and chinese cabbage (Brassica pekinensis) collected from 6 markets in the Taegu city, was conducted for the discovery of helminth eggs and larvae, from July 1982 to June 1983. The results were compared with the data obtained from vegetables collected at the same markets by Lee (1969) and Choi and Lee (1972). Both sides of vegetable leaves were washed carefully with a hard brush, and the species of parasites and the mean number of parasites per 200 g of vegetable were determined.
When vegetable were examined, 4 species of parasite eggs (ascarid, Trichostrongylus, liver fluke, and hookworms) and 2 larvae (filariform and rhabditoid larvae) were found. Of the parasite discovered, ascarid egg was found to be highest (4.2 percent), followed by hookworm egg (3.6 percent). The mean number of ascarid egg per 200 grams of vegetable was 0.6 in young radishes, and 0.3 in both lettuces and chinese cabbages. Similarly, the number of filariform larva of hookworm was 0.4 in young radishes, 0.3 in lettuces, and 0.l in chinese cabbages, and the number of rhabditoid larva was 0.2 in young radishes, 0.1 in lettuces, and 0.05 in chinese cabbages. In the results obtained by Lee (1969) and Choi and Lee (1972), the mean number of ascarid egg per 200 grams of vegetable was 7.5 in young radishes, 3.l in lettuces, and 0.5 in chinese cabbages. By contrast, in the present study it was 0.6 in young radishes and 0.3 in both lettuces and chinese cabbages. These results suggest that there has been significant reduction in the incidence of parasite egg and larva on vegetable leaves during the past 10 years.
Aedes alboscutellatus was recorded first in Korea. This mosquito was collected near Demilitarized Zone of Korea Penninsula from 1979-1980. Its morphology and taxonomical position was described(abstracted from English content).
Citations
Citations to this article as recorded by
Molecular confirmation of a new mosquito record Aedes lineatopennis from Odisha along with a comprehensive update of mosquito (Diptera: Culicidae) fauna in India Sushmita Swain, Gaurav Sharma, Surabhi Chittora, Devi Shankar Suman Biologia.2025;[Epub] CrossRef
Taxonomic Review and Revised Keys of the Korean Mosquitoes (Diptera: Culicidae) Han‐Il REE Entomological Research.2003; 33(1): 39. CrossRef
Checklist of mosquitoes (Culicidae) in Korea Kwan Woo Lee The Korean Journal of Parasitology.1987; 25(2): 207. CrossRef
The distribution, external morphology, radula, chromosome numbers of Planorbidae snails were studied. The specimens were collected at four stations in Nonsangun, Kongjugun, and Daedukgun which are located around Geum river. Three genera and three species of Planorbidae, Hippeutis cantori, Segmentina hemisphaerula and Gyraulus convexiusculus, were collected. H. cantori was the most abundant species among the three species. G. convexiusculus was the least abundant one. Each species could be identified on the basis of its external characteristic, since the periphery of each species has a peculiar shape. H. cantori was the largest one among the three species. The radula formula of each species was very similar to other species. The size of radula was proportional to the size of shell. The radula formulae of H.
cantori, S. hemisphaerula, and G. convexiusculus were 29:1:29, 23:l:23, and 16:1:16 respectively. The difference of radula formula could be found in the total numbers of laternal and marginal teeth. The haploid chromosome number of H. cantori was eighteen (n=18). S. hemisphaerula and G.
convexiusculus were assumed to be same in their chromosome numbers (n=18).
Citations
Citations to this article as recorded by
The life cycle and larval development of Fibricola seoulensis (Trematoda: Diplostomatidae) Byong Seol Seo, Soon Hyung Lee, Jong Yil Chai, Sung Jong Hong, Sung Tae Hong The Korean Journal of Parasitology.1988; 26(3): 179. CrossRef
First
Prev
