trivolvis obtained from the kidneys of naturally infected Rana species tadpoles. Cysts were excysted in an alkaline trypsin-bile salts medium and the percentage of excystation was compared with that from previous studies done on cysts obtained from the kidneys of snails. The percentage of excystation of E. trivolvis metacercariae from tadpole kidneys was similar to that reported for previous studies on cysts obtained from experimentally infected gastropod hosts.
The possible role of tadpoles as an agent for the transmission of Echinostoma and echinostomiasis to humans is discussed.
Citations
Citations to this article as recorded by
Larval wood frog (Rana [=Lithobates] sylvatica) development and physiology following infection with the trematode parasite, Echinostoma trivolvis S.A. Orlofske, L.K. Belden, W.A. Hopkins Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology.2013; 164(3): 529. CrossRef
Relative Toxicity of Malathion to Trematode-Infected and Noninfected Rana palustris Tadpoles Sarah A. Budischak, Lisa K. Belden, William A. Hopkins Archives of Environmental Contamination and Toxicology.2009; 56(1): 123. CrossRef
Moderate Echinostoma trivolvis Infection Has No Effects on Physiology and Fitness-Related Traits of Larval Pickerel Frogs (Rana palustris) Sarah A. Orlofske, Lisa K. Belden, William A. Hopkins Journal of Parasitology.2009; 95(4): 787. CrossRef
Toxoplasma gondii, an intracellular protozoan infecting many kinds of eukaryotic cells, has been used to experimentally infect macrophages, epithelial cells, fibroblasts, and various cancer cells, but rarely T and B lymphocytes or granulocytes. The present study was performed to determine the susceptibility of murine (BALB/c or CBA) splenic T and B lymphocytes, and granulocytes to infection with T. gondii RH tachyzoites. The ultrastructure of the infected host cells was observed by TEM, and the degree of intracellular parasite proliferation was quantified using 3H-uracil uptake assay. At 24 hrs post-culture, the host cell cytoplasm was found to contain 1 or 2, or a maximum of 7-8 tachyzoites.
Infected T lymphocytes demonstrated a peripherally displaced nucleus, a parasitophorous vacuole enveloping the parasite, and an increased number of mitochondria. In B lymphocytes infected with tachyzoites, RER was not well developed compared to uninfected B lymphocytes. Uninfected granulocytes contained many electron-dense granules, but T.
gondii-infected granulocytes demonstrated a decreased number of granules. Based on the 3H-uracil uptake assay, the susceptibility of T and B lymphocytes, and granulocytes, to infection with T. gondii tachyzoites was fairly high irrespective of cell type and strain of mouse. This strongly suggests deterioration in the functioning of infected host immune cells.
Citations
Citations to this article as recorded by
Anti-Toxoplasma gondii IgM Long Persistence: What Are the Underlying Mechanisms? José Antonio Vargas-Villavicencio, Irma Cañedo-Solares, Dolores Correa Microorganisms.2022; 10(8): 1659. CrossRef
In vivo study of toxoplasmic parasitemia using interferon-γ-deficient mice: Absolute cell number of leukocytes, parasite load and cell susceptibility Kazumi Norose, Koji Naoi, Hao Fang, Akihiko Yano Parasitology International.2008; 57(4): 447. CrossRef
The ProtozoanNeospora caninumDirectly Triggers Bovine NK Cells To Produce Gamma Interferon and To Kill Infected Fibroblasts Preben Boysen, Siv Klevar, Ingrid Olsen, Anne K. Storset Infection and Immunity.2006; 74(2): 953. CrossRef
Suppressed Cytokine and Immunoglobulin Secretions by Murine Splenic Lymphocytes Infected In Vitro with Toxoplasma gondii Tachyzoites S-M. Guk, J. Kook, Y-H. Jeon, J-H. Choi, E-T. Han, E-H. Shin, J-Y. Chai Journal of Parasitology.2005; 91(2): 467. CrossRef
USE OF MONOCLONAL ANTIBODIES FOR FLOW CYTOMETRIC DETECTION OF INTRACELLULAR TOXOPLASMA GONDII IN MURINE SPLENIC LYMPHOCYTES Eun-Hee Shin, Sung-Bum Kim, Ho-Woo Nam, Eun-Taek Han, Jae-Hwan Park, Hye-Jin Ahn, Jong-Yil Chai Journal of Parasitology.2004; 90(1): 161. CrossRef
Laboratory passage and characterization of an isolate of Toxoplasma gondii from an ocular patient in Korea Jong-Yil Chai, Aifen Lin, Eun-Hee Shin, Myoung-Don Oh, Eun-Taek Han, Ho-Woo Nam, Soon-Hyung Lee The Korean Journal of Parasitology.2003; 41(3): 147. CrossRef
A role of carboxy-terminal region of Toxoplasma gondii-heat shock protein 70 in enhancement of T. gondii infection in mice Hye-Seong Mun, Kazumi Norose, Fumie Aosai, Mei Chen, Akihiko Yano The Korean Journal of Parasitology.2000; 38(2): 107. CrossRef
Sequential analysis of cell differentials and IFN-γ production of splenocytes from mice infected with Toxoplasma gondii Young-Ha Lee, Dae-Whan Shin, Lloyd H. Kasper The Korean Journal of Parasitology.2000; 38(2): 85. CrossRef
Clonorchis sinensis is a liver fluke which is the most prevalent helminth of humans in Korea. The better diagnostic measure of clonorchiasis is required for its nationwide control program. The present study observed antigenic bands of C. sinensis and reacting immunoglobulins in serum of infected residents. Adult C. sinensis were recovered from experimentally infected rabbits and soluble crude extract of the worms was used as the antigen after supplementation of E-64, a cysteine proteinase inhibitor. SDS-PAGE of the crude antigen resolved more than 20 protein bands between 200 and 14 kDa. The sera of infected humans collected at an endemic village showed specific IgG and IgE antibodies but little IgM and IgA antibodies. The protein bands of 94, 80, 72, 68, 52, 47, 43, 37, 34, and 28-25 kDa strongly reacted with serum Ig(GMA) or IgG antibody and 64, 62, 52, 47, 44, 34, 28, and 26 kDa bands reacted with serum IgE antibody.
However, the 94, 80, 72, 68, 64, 62, 52, 47, and 40 kDa bands of C. sinensis antigen were found non-specific. The protein bands of 43, 34, and 28-25 kDa of C. sinesis are primary target molecules of further analysis.
Citations
Citations to this article as recorded by
Novel mechanism of hepatobiliary system damage and immunoglobulin G4 elevation caused by Clonorchis sinensis infection Xin-He Zhang, Die Huang, Yi-Ling Li, Bing Chang World Journal of Clinical Cases.2021; 9(23): 6639. CrossRef
The serological diagnosis of human clonorchiasis by time-resolved fluoroimmunoassay based on GST2-specific IgG4 detection Jin Xu, Lexun Wang, Chuanhuan Deng, Xuchu Hu, Ran Li, Tingjin Chen, Dan Ning, Yingsong Wu, Yan Huang, Xuerong Li, Zhongdao Wu, Xinbing Yu, Yonglong Li Parasitology Research.2014; 113(1): 149. CrossRef
Multiple recombinant antigens of Clonorchis sinensis for serodiagnosis of human clonorchiasis Shunyu Li, Jung Guk Shin, Pyo Yun Cho, Tae Im Kim, Sung-Tae Hong, Sung-Jong Hong Parasitology Research.2011; 108(5): 1295. CrossRef
Serodiagnostic applicability of recombinant antigens of Clonorchis sinensis expressed by wheat germ cell-free protein synthesis system Chenghua Shen, Jong-Ae Lee, Sonia Refaat Ahmed Allam, Young Mee Bae, Eun-Taek Han, Satoru Takeo, Takafumi Tsuboi, Sung-Tae Hong, Min-Ho Choi Diagnostic Microbiology and Infectious Disease.2009; 64(3): 334. CrossRef
Changing Patterns of Serum and Bile Antibodies in Re-infected Rats with Clonorchis sinensis Hongman Zhang, Byung-Suk Chung, Shunyu Li, Min-Ho Choi, Sung-Tae Hong The Korean Journal of Parasitology.2008; 46(1): 17. CrossRef
Clonorchis sinensis: Development and evaluation of a nested polymerase chain reaction (PCR) assay Ammini Parvathi, H. Sanath Kumar, B. Kenchanna Prakasha, Jieyuan Lu, Xuenian Xu, Wei Hu, Zheng Feng, Indrani Karunasagar, Iddya Karunasagar Experimental Parasitology.2007; 115(3): 291. CrossRef
The identification of a Clonorchis sinensis gene encoding an antigenic egg protein Mejeong Lee, Young-Bae Chung, Suk-Keun Lee, Byung-Suk Chung, Shunyu Li, Min-Ho Choi, Sung-Tae Hong Parasitology Research.2005; 95(3): 224. CrossRef
Organ-specific antigens of Clonorchis sinensis Shunyu Li, Byung-Suk Chung, Min-Ho Choi, Sung-Tae Hong The Korean Journal of Parasitology.2004; 42(4): 169. CrossRef
Relationships Between IgG, IgM, IgE and Resistance to Reinfection During the Early Phase of Infection withClonorchis sinensisin Rats Fu‐Shi Quan, Takaaki Matsumoto, Young‐Oh Shin, Young‐Ki Min, Hun‐Mo Yang, Timothy Othman, Jeong‐Beom Lee Immunological Investigations.2004; 33(1): 51. CrossRef
Specific and common antigens of Clonorchis sinensis and Opisthorchis viverrini (Opisthorchidae, Trematoda) Min-Ho Choi, Jin-Sook Ryu, Mejeong Lee, Shunyu Li, Byung-Suk Chung, Jong-Yil Chai, Paiboon Sithithaworn, Smarn Tesana, Sung-Tae Hong The Korean Journal of Parasitology.2003; 41(3): 155. CrossRef
Excretory-secretory antigen is better than crude antigen for the serodiagnosis of clonorchiasis by ELISA Min-Ho Choi, Il Chan Park, Shunyu Li, Sung-Tae Hong The Korean Journal of Parasitology.2003; 41(1): 35. CrossRef
Characterization of partially purified 8 kDa antigenic protein of Clonorchis sinensis Young-Bae Chung, Mejeong Lee, Hyun-Jong Yang, Byung-Suk Chung, Shun-Yu Lee, Min-Ho Choi, Sung-Tae Hong The Korean Journal of Parasitology.2002; 40(2): 83. CrossRef
EXPRESSION OF CYSTEINE PROTEINASE OF CLONORCHIS SINENSIS AND ITS USE IN SERODIAGNOSIS OF CLONORCHIASIS Byoung-Kuk Na, Hye-Jeong Lee, Shin-Hyeong Cho, Hyeong-Woo Lee, Jung-Hwa Cho, Weon-Gyu Kho, Joon-Sang Lee, Jong-Soo Lee, Kyoung-Ju Song, Po-Hyun Park, Chul-Yong Song, Tong-Soo Kim Journal of Parasitology.2002; 88(5): 1000. CrossRef
PURIFICATION AND CHARACTERIZATION OF A 7-KDA PROTEIN FROM CLONORCHIS SINENSIS ADULT WORMS Hye-Jeong Lee, Chang-Seok Lee, Beom-Su Kim, Kyoung-Hwan Joo, Joon-Sang Lee, Tong-Soo Kim, Hak R. Kim Journal of Parasitology.2002; 88(3): 499. CrossRef
Antigenic profile and localization of Clonorchis sinensis proteins in the course of infection Sung-Jong Hong, Tae Yun Kim, Kye-Yong Song, Woon-Mok Sohn, Shin-Yong Kang The Korean Journal of Parasitology.2001; 39(4): 307. CrossRef
Identification of a Clonorchis sinensis gene encoding a vitellaria antigenic protein containing repetitive sequences Hye-Jin Yang, Soon-Jung Park, Kyung-il Im, Tai-Soon Yong Molecular and Biochemical Parasitology.2000; 111(1): 213. CrossRef
Molecular cloning and immunological characterization of phosphoglycerate kinase from Clonorchis sinensis Sung-Jong Hong, Kee-Young Seong, Woon-Mok Sohn, Kye-Yong Song Molecular and Biochemical Parasitology.2000; 108(2): 207. CrossRef
Shared Epitope for Monoclonal IR162 BetweenAnisakis simplexLarvae andClonorchis sinensisand Cross-Reactivity Between Antigens Jun kyong Cho, Sung-Weon Cho Journal of Parasitology.2000; 86(5): 1145. CrossRef
Usefulness of IgG4 subclass antibodies for diagnosis of human clonorchiasis Sung-Tae Hong, Mejeong Lee, Nak-Jin Sung, Sang Rock Cho, Jong-Yil Chai, Soon-Hyung Lee The Korean Journal of Parasitology.1999; 37(4): 243. CrossRef
Immunodiagnosis of clonorchiasis using a recombinant antigen T S Yong, H J Yang, S J Park, Y K Kim, D H Lee, S M Lee The Korean Journal of Parasitology.1998; 36(3): 183. CrossRef
A Clonorchis sinensis-specific antigen that detects active human clonorchiasis S I Kim The Korean Journal of Parasitology.1998; 36(1): 37. CrossRef
The localization of worm antigen of Neodiplostomum seoulense was examined by immuno-electronmicroscopic observation. Not only the immunized serum of mice with crude worm extract of N. seoulense but also serum of infected mouse were reacted to the worm section. Using immunized serum as primary antibody, the gold particles were deposited on the rough endoplasmic reticulum of the cell of tribocytic organ, spermatozoa in the seminal vesicle, microvilli of the caecum and vitelline follicle. Using infected serum, gold particles were deposited only on the vitelline follicle prominently.
This finding suggested that the tribocytic organ, seminal vesicle, caeca and vitelline follicles may play a role of antigen to immunized serum with crude worm extract of N.
seoulense, whereas the vitelline follicle, to the infected serum.
Citations
Citations to this article as recorded by
Foodborne Intestinal Flukes in Southeast Asia Jong-Yil Chai, Eun-Hee Shin, Soon-Hyung Lee, Han-Jong Rim The Korean Journal of Parasitology.2009; 47(Suppl): S69. CrossRef
Food-borne intestinal trematode infections in the Republic of Korea Jong-Yil Chai, Soon-Hyung Lee Parasitology International.2002; 51(2): 129. CrossRef
The gene encoding the 33 kDa piroplasm surface protein of Theileria sergenti isolated in Korea was cloned and the nucleotide sequence was determined by dideoxy chain termination method. The cloned gene corresponds to 869 bp encoding an open reading frame 283 amino acids. Comparison of the sequence between Korean and Japanese isolates showed 99.4% homology rate in the nucleotide sequence and 98.9% homology rate in the amino acid sequence.
Citations
Citations to this article as recorded by
Polymorphism Analysis of Chinese Theileria sergenti Using Allele-Specific Polymerase Chain Reaction of the Major Piroplasm Surface Protein Gene Ai Hong Liu, Gui Quan Guan, Jun Long Liu, Zhi Jie Liu, Neil Leblanc, You Quan Li, Jin Liang Gao, Mi Ling Ma, Qing Li Niu, Qiao Yun Ren, Qi Bai, Hong Yin, Jian Xun Luo Journal of Parasitology.2011; 97(1): 116. CrossRef
Antigenic diversity ofTheileriamajor piroplasm surface protein gene in Jeju black cattle Myung-Soon Ko, Kyoung-Kap Lee, Kyu-Kye Hwang, Byung-Sun Kim, Gui-Cheol Choi, Young-Min Yun Journal of Veterinary Science.2008; 9(2): 155. CrossRef
SEROLOGICAL INVESTIGATION OF THEILERIA SERGENTI USING LATEX AGGLUTINATION TEST IN SOUTH KOREA Wooseog Jeong, Chang Hee Kweon, Jong Man Kim, Hwan Jang, Sang Gi Paik Journal of Parasitology.2005; 91(1): 164. CrossRef
Expression of major piroplasm protein (p33) of Theileria sergenti (Korean isolate) and its immunogenicity in guinea pigs Seung-Won Kang, Chang-Hee Kweon, Eun-Jin Choi, Yong-Dhuk Yoon The Korean Journal of Parasitology.1999; 37(4): 277. CrossRef
Rapid detection of Theileria sergenti by polymerase chain reaction E J Choi, S W Kang, C H Kweon, W S Jeong, Y D Yoon, H J Song The Korean Journal of Parasitology.1997; 35(2): 111. CrossRef
Four separate pairs of oligonucleotide primers within the coding region in a T. sergenti 33-kDa surface protein gene were selected to detect T. sergenti by PCR. The specificity of PCR-amplified DNA was examined by digestion with restriction enzyme and Southern blot hybridization using T.
sergenti p33 DNA probe. PCR appears to be specific for T.
sergenti, without detectable signals from uninfected erythrocytes, uninfected bovine leukocytes and other hemoparasites, including A. marginale and B. ovata. Although 46 of 71 specimens (64.8%) from grazing cattle were microscopically positive, PCR in this study showed that 64 specimens (88.7%) were positive. Therefore, PCR proves a useful diagnostic tool for detecting T. sergenti-infected cattle. In addition, it is also revealed that PCR was significantly more sensitive than traditional microscopic examination using Giemsa's stain.
Citations
Citations to this article as recorded by
Seasonal changes in hemograms and Theileria orientalis infection rates among Holstein cattle pastured in the mountains in the Republic of Korea Kyoung-Seong Choi, Do-Hyeon Yu, Joon-Seok Chae, Bae-Keun Park, Jae-Gyu Yoo, Jinho Park Preventive Veterinary Medicine.2016; 127: 77. CrossRef
A survey for tick-borne pathogens in Korean native cattle from northern area of Gyeongbuk Jae-Cheong Cho, Woo-Jin Jeon, Seon-Soo Kim, Seong-Guk Kim Korean Journal of Veterinary Service.2016; 39(1): 29. CrossRef
Rapid discrimination and quantification of Theileria orientalis types using ribosomal DNA internal transcribed spacers Joseph Kamau, Bashir Salim, Naoki Yokoyama, Peter Kinyanjui, Chihiro Sugimoto Infection, Genetics and Evolution.2011; 11(2): 407. CrossRef
High prevalence of Theileria sp. in wild Chinese Water Deer (Hydropotes inermis argyropus) in South Korea Jae-Ik Han, Hye-Jin Jang, Sook-Jin Lee, Ki-Jeong Na Veterinary Parasitology.2009; 164(2-4): 311. CrossRef
SEROLOGICAL INVESTIGATION OF THEILERIA SERGENTI USING LATEX AGGLUTINATION TEST IN SOUTH KOREA Wooseog Jeong, Chang Hee Kweon, Jong Man Kim, Hwan Jang, Sang Gi Paik Journal of Parasitology.2005; 91(1): 164. CrossRef
Fast Diagnosis of Bovine Theileriosis by Whole Blood PCR and Microchip Electrophoresis
Bulletin of the Korean Chemical Society.2004; 25(5): 757. CrossRef
Diagnosis of Bovine Theileriosis by Direct PCR and Electrophoresis from Whole Blood Without DNA Extraction Seong Ho Kang, Sangmin Jang, Joon-Seok Chae, Yongseong Kim Journal of the Korean Chemical Society.2003; 47(2): 127. CrossRef
Prevalence of Theileria sergenti infection in Korean native cattle by polymerase chain reaction Kun-Ho Song, Byung-Chan Sang The Korean Journal of Parasitology.2003; 41(3): 141. CrossRef
Diagnosis and quantification of Theileria sergenti using TaqMan PCR Wooseog Jeong, Chang Hee Kweon, Seung Won Kang, Sang Gi Paik Veterinary Parasitology.2003; 111(4): 287. CrossRef
Expression of major piroplasm protein (p33) of Theileria sergenti (Korean isolate) and its immunogenicity in guinea pigs Seung-Won Kang, Chang-Hee Kweon, Eun-Jin Choi, Yong-Dhuk Yoon The Korean Journal of Parasitology.1999; 37(4): 277. CrossRef
Acanthamoeba sp. YM-4 is similar to A. culbertsoni based upon morphological characteristics of trophozoites and cysts. However, based on other characteristics, pathogenicity to mice, in vitro cytotoxicity and isoenzyme patterns. Acanthamoeba sp. YM-4 was quite different from A.
culbertsoni. Restriction fragment length polymorphism (RFLP) analysis of mtDNA is useful in the classification of members belonging to the genus Acanthamoeba. Therefore, in this study, RFLP analysis of Acanthamoeba mtDNAs was accomplished using five restriction enzymes: HaeIII, HindIII, ClaI, PvuII and SalI. Each restriction enzyme produced approximately 3-15 fragments (range: from 0.6 kbp to 34.4 kbp). The mtDNA genome size, calculated by the summation of restriction fragments, averaged 46.4 kbp in Acanthamoeba sp. YM-4, 48.3 kbp in A. culbertsoni and 48.8 kbp in A. polyphaga, respectively. Digested mtDNA fragments of Acanthamoeba sp.
YM-4 contained nine and seven same size fragments, respectively, from a total of 67 and 69 fragments observed in A. culbertsoni and A. polyphaga. An estimate of the genetic divergence was 10.1% between Acanthamoeba sp. YM-4 and A. culbertsoni, and 9.9% between Acanthamoeba sp. YM-4 and A. polyphaga.
Citations
Citations to this article as recorded by
Acanthamoeba sohi, n. sp., a pathogenic Korean isolate YM-4 from a freshwater fish Kyung-il Im, Ho-Joon Shin The Korean Journal of Parasitology.2003; 41(4): 181. CrossRef
Transmission electron microscopy of an Acanthamoeba isolate (KA/L5) from a contact lens case revealed bacterial endosymbionts within cytoplasm of the amoebae. The Acanthamoeba isolate belonged to the morphological group II.
Based on the polymerase chain reaction (PCR)-restriction fragment length polymorphism (RFLP) of 18S ribosomal RNA coding DNA (rDNA), the isolate was identified as A.
lugdunensis. Strain typing by isoenzyme analysis using isoelectric focusing (IEF) and mitochondrial (Mt) DNA RFLP revealed that the isolate was closely related with KA/L1, the most predominant type of isolates from contact lens storage cases, KA/E2, a clinical isolate, KA/W4, previously reported to host endosymbionts, and L3a strains of A.
lugdunensis. The endosymbionts were similar to those of KA/W4 in aspects that they were randomly distributed in both trophozoites and cysts, and were rod-shaped bacteria measuring approximately 1.38 x 0.50 microns. But the number of endosymbionts per amoeba was significantly lower than that of KA/W4. They were neither limited by phagosomal membranes nor included in lacunaelike structure.
Citations
Citations to this article as recorded by
Contamination of fresh vegetables in municipal stores with pathogenic Acanthamoeba genotypes; a public health concern Marziye Fatemi, Maryam Niyyati, Soheila Rouhani, Seyed Ahmad Karamati, Hamed Mirjalali, Panagiotis Karanis International Journal of Environmental Health Research.2023; 33(10): 1010. CrossRef
A Systematic Review of Intracellular Microorganisms within Acanthamoeba to Understand Potential Impact for Infection Binod Rayamajhee, Dinesh Subedi, Hari Kumar Peguda, Mark Duncan Willcox, Fiona L. Henriquez, Nicole Carnt Pathogens.2021; 10(2): 225. CrossRef
Various brain-eating amoebae: the protozoa, the pathogenesis, and the disease Hongze Zhang, Xunjia Cheng Frontiers of Medicine.2021; 15(6): 842. CrossRef
Endosymbionts of Acanthamoeba Isolated from Domestic Tap Water in Korea Seon Hee Choi, Min Kyoung Cho, Soon Cheol Ahn, Ji Eun Lee, Jong Soo Lee, Dong-Hee Kim, Ying-Hua Xuan, Yeon Chul Hong, Hyun Hee Kong, Dong Il Chung, Hak Sun Yu The Korean Journal of Parasitology.2009; 47(4): 337. CrossRef
Natural occurrence of Mycobacterium as an endosymbiont of Acanthamoeba isolated from a contact lens storage case Hak Sun Yu, Hae Jin Jeong, Yeon-Chul Hong, Seong-Yong Seol, Dong-Il Chung, Hyun-Hee Kong The Korean Journal of Parasitology.2007; 45(1): 11. CrossRef
Molecular characterization of bacterial endosymbionts of Acanthamoeba isolates from infected corneas of Korean patients Ying-Hua Xuan, Hak Sun Yu, Hae Jin Jeong, Sung-Yong Seol, Dong-Il Chung, Hyun-Hee Kong The Korean Journal of Parasitology.2007; 45(1): 1. CrossRef
Phylogenetic relationships among Acanthamoeba spp. based on PCR-RFLP analyses of mitochondrial small subunit rRNA gene Hak-sun Yu, Mee-yul Hwang, Tae-ook Kim, Ho-cheol Yun, Tae-ho Kim, Hyun-hee Kong, Dong-il Chung The Korean Journal of Parasitology.1999; 37(3): 181. CrossRef
This study was performed to observe intestinal pathology in early infection by Centrocestus armatus. The flukes were in the lowermost part of the intervillous space of the duodenum and jejunum from 1 day to 7 days postinfection (PI). The stroma of villi around the young fluke was edematous and infiltrated by inflammatory cells such as lymphocytes, plasma cells and eosinophils. The crypt became mildly hyperplastic and villi were moderately atrophied at 4 days PI. The intestinal lesion produced was confined to the areas around the fluke. The pathologic findings were not significantly different between 1,000 and 5,000 metacercariae infection groups. It is suggested that the lesion should be produced by mechanical destruction of the fluke on the enteroepithelial cells.
Citations
Citations to this article as recorded by
Chronological analysis of the damages caused by the metacercariae of Centrocestus formosanus in the gills of Cyprinus carpio and lesions caused by the adult flukes in Ardeola ralloides: An experimental study Bannak G.D. Sumuduni, Dona H.N. Munasinghe, Appudurai Arulkanthan International Journal of Veterinary Science and Medicine.2018; 6(2): 165. CrossRef
Experimental centrocestiasis: Worm burden, morphology and fecundity of Centrocestus formosanus (Trematoda: Heterophyidae) in dexamethasone immunosuppressed mice Hudson Alves Pinto, Vitor Luís Tenório Mati, Alan Lane de Melo Parasitology International.2015; 64(5): 236. CrossRef
Insights into regulatory molecules of intestinal epithelial cell turnover during experimental infection by Heterophyes heterophyes Dalia S. Ashour, Ahmad A. Othman, Dina A. Radi Experimental Parasitology.2014; 143: 48. CrossRef
Centrocestus formosanus(Heterophyidae): Human Infections and the Infection Source in Lao PDR Jong-Yil Chai, Woon-Mok Sohn, Tai-Soon Yong, Keeseon S. Eom, Duk-Young Min, Mi Youn Lee, Hyemi Lim, Bounnaloth Insisiengmay, Bounlay Phommasack, Han-Jong Rim Journal of Parasitology.2013; 99(3): 531. CrossRef
Foodborne Intestinal Flukes in Southeast Asia Jong-Yil Chai, Eun-Hee Shin, Soon-Hyung Lee, Han-Jong Rim The Korean Journal of Parasitology.2009; 47(Suppl): S69. CrossRef
Food-borne intestinal trematode infections in the Republic of Korea Jong-Yil Chai, Soon-Hyung Lee Parasitology International.2002; 51(2): 129. CrossRef
Surface ultrastructure of juvenile and adult stages of Centrocestus armatus Ho-Choon Woo, Myung-Deuk Seo, Sung-Jong Hong Journal of Helminthology.1998; 72(3): 215. CrossRef
Cleaving host immunoglobulins is a well known mechanism of evading host immune reactions exploited by helminth parasites. Secreted cysteine proteases of helminth are a part of enzymes cleaving host IgG. Paragonimus westermani produces at least six different species of the cysteine protease in its developmental stages. This study was undertaken to evaluate comparatively the activities against human IgG by the different enzymes. When the metacercariae, which secrete 27 and 28 kDa cysteine proteases, were incubated in human IgG solution, IgG was degraded at its hinge region. Further incubation resulted complete hydrolysis. From 4-week and 7-week old juveniles and 16-week old adults of P. westermani, five different enzymes at 15, 17, 27, 28 and 53 kDa have been purified, if the enzyme with the same molecular mass is regarded to be identical. In cleaving human IgG, each cysteine protease exhibited decreasing activities with age.
Citations
Citations to this article as recorded by
North American Paragonimiasis (Caused byParagonimus kellicotti) in the Context of Global Paragonimiasis Gary W. Procop Clinical Microbiology Reviews.2009; 22(3): 415. CrossRef
Partial Purification and Characterization of a Cysteine Protease Inhibitor from the Plerocercoid of Spirometra erinacei Young-Bae Chung, Hyun-Jong Yang The Korean Journal of Parasitology.2008; 46(3): 183. CrossRef
Antigenic Properties of Cystatin-binding Cysteine Proteinases from Neodiplostomum seoulense Tae-Yun Kim, Kye-Young Han, Eun-Hee Shin, Jong-Yil Chai Journal of Parasitology.2008; 94(3): 654. CrossRef
Antigenic Properties of Cystatin-binding Cysteine Proteinases from Neodiplostomum seoulense Tae-Yun Kim, Kye-Young Han, Eun-Hee Shin, Jong-Yil Chai Journal of Parasitology.2008; 94(3): 654. CrossRef
Cloning and characterization of cathepsin L-like peptidases of Echinococcus multilocularis metacestodes Yasuhito Sako, Hiroshi Yamasaki, Kazuhiro Nakaya, Minoru Nakao, Akira Ito Molecular and Biochemical Parasitology.2007; 154(2): 181. CrossRef
Critical roles for excretory-secretory cysteine proteases during tissue invasion of Paragonimus westermani newly excysted metacercariae Byoung-Kuk Na, Seon-Hee Kim, Eung-Goo Lee, Tong-Soo Kim, Young-An Bae, Insug Kang, Jae-Ran Yu, Woon-Mok Sohn, Seung-Yull Cho, Yoon Kong Cellular Microbiology.2006; 8(6): 1034. CrossRef
Molecular and biochemical characterization of hemoglobinase, a cysteine proteinase, in Paragonimus westermani Joon-Hyuck Choi, Jae-Hyuk Lee, Hak-Sun Yu, Hae-Jin Jeong, Jin Kim, Yeon-Chul Hong, Hyun-Hee Kong, Dong-Il Chung The Korean Journal of Parasitology.2006; 44(3): 187. CrossRef
Identification of immunodominant excretory–secretory cysteine proteases of adult Paragonimus westermani by proteome analysis Eung‐Goo Lee, Byoung‐Kuk Na, Young‐An Bae, Seon‐Hee Kim, Eun‐Young Je, Jeong‐Won Ju, Shin‐Hyeong Cho, Tong‐Soo Kim, Shin‐Yong Kang, Seung‐Yull Cho, Yoon Kong PROTEOMICS.2006; 6(4): 1290. CrossRef
Excretory-Secretory Products Produced by Paragonimus westermani Differentially Regulate the Nitric Oxide Production and Viability of Microglial Cells Youngnam Jin, Jae-Chul Lee, In Young Choi, Eun A. Kim, Myeong Heon Shin, Won-Ki Kim International Archives of Allergy and Immunology.2006; 139(1): 16. CrossRef
Degranulation of human eosinophils induced by Paragonimus westermani-secreted protease Myeong Heon Shin, Young-Bae Chung, Hirohito Kita The Korean Journal of Parasitology.2005; 43(1): 33. CrossRef
Partial characterization of a 29 kDa cysteine protease purified from Taenia solium metacestodes Ji-Young Kim, Hyun-Jong Yang, Kwang-Sig Kim, Young-Bae Chung The Korean Journal of Parasitology.2005; 43(4): 157. CrossRef
The uptake of Texas Red-BSA in the excretory system of schistosomes and its colocalisation with ER60 promoter-induced GFP in transiently transformed adult males Volker Wippersteg, Fabio Ribeiro, Stefanie Liedtke, John R Kusel, Christoph G Grevelding International Journal for Parasitology.2003; 33(11): 1139. CrossRef
Excretory bladder: the source of cysteine proteases in Paragonimus westermani metacercariae Hyun Jong Yang, Young Bae Chung, Shin Yong Kang, Yoon Kong, Seung Yull Cho The Korean Journal of Parasitology.2002; 40(2): 89. CrossRef
EXPRESSION OF CYSTEINE PROTEINASE OF CLONORCHIS SINENSIS AND ITS USE IN SERODIAGNOSIS OF CLONORCHIASIS Byoung-Kuk Na, Hye-Jeong Lee, Shin-Hyeong Cho, Hyeong-Woo Lee, Jung-Hwa Cho, Weon-Gyu Kho, Joon-Sang Lee, Jong-Soo Lee, Kyoung-Ju Song, Po-Hyun Park, Chul-Yong Song, Tong-Soo Kim Journal of Parasitology.2002; 88(5): 1000. CrossRef
Cystatin Capture Enzyme-Linked Immunosorbent Assay for Serodiagnosis of Human Clonorchiasis and Profile of Captured Antigenic Protein ofClonorchis sinensis Tae Yun Kim, Shin-Yong Kang, Sun Hyo Park, Kom Sukontason, Kabkaew Sukontason, Sung-Jong Hong Clinical Diagnostic Laboratory Immunology.2001; 8(6): 1076. CrossRef
Cysteine Protease Secreted byParagonimus westermaniAttenuates Effector Functions of Human Eosinophils Stimulated with Immunoglobulin G W. A. Petri, Myeong Heon Shin, Hirohito Kita, Hae Young Park, Ju Young Seoh Infection and Immunity.2001; 69(3): 1599. CrossRef
Excretory-secretory product of Paragonimus westermani newly excysted metacercariae inhibits superoxide production of granulocytes stimulated with IgG Myeong Heon Shin The Korean Journal of Parasitology.2000; 38(2): 103. CrossRef
Proteolytic activity of cysteine protease in excretory–secretory product of Paragonimus westermani newly excysted metacercariae pivotally regulates IL‐8 production of human eosinophils Myeong Heon Shin, Soo Young Lee Parasite Immunology.2000; 22(10): 529. CrossRef
Structural and Immunological Characteristics of a 28-Kilodalton Cruzipain-Like Cysteine Protease ofParagonimus westermaniExpressed in the Definitive Host Stage Doo-Hee Yun, Joon-Yong Chung, Young-Bae Chung, Young-Yil Bahk, Shin-Yong Kang, Yoon Kong, Seung-Yull Cho Clinical Diagnostic Laboratory Immunology.2000; 7(6): 932. CrossRef
First
Prev
