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Volume 44(3); September 2006

Mini Review

A successful experience of soil-transmitted helminth control in the Republic of Korea
Sung-Tae Hong, Jong-Yil Chai, Min-Ho Choi, Sun Huh, Han-Jong Rim, Soon-Hyung Lee
Korean J Parasitol 2006;44(3):177-185.
Published online September 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.3.177

Soil-transmitted helminths (STH), namely Ascaris, Trichuris and hookworms (Ancylostoma and Necator), present a global health problem to about a half of the earth's population. In the Republic of Korea, STH were highly prevalent and were considered a high priority target for national control. To promote the control, a non-governmental organization named Korea Association for Parasite Eradication (currently Korea Association of Health Promotion) was founded in 1964, and mass fecal examination followed by selective mass chemotherapy with anthelmintics was performed twice a year from 1969 to 1995 targeting whole nationwide schoolchildren. Meanwhile, decreasing patterns of national STH infections have been monitored by 7 times' quinquennial national surveys targeting general population. In 1971, the overall intestinal helminth egg positive rate was 84.3% (Ascaris 58.2%, Trichuris 65.4%, and hookworms 10.7%), which became 63.2% in 1976, 41.1% in 1981, 12.9% in 1986, 3.8% in 1992, 2.4% in 1997, and 4.3% (Ascaris 0.03%, Trichuris 0.02%, and hookworms 0%) in 2004. During the control period, national economy rapidly developed, and living standards including environment, sanitation, and agricultural technology greatly improved, which undoubtedly boosted the STH control effects. Our experience indicates that social driving force to establish an eligible national control system to conduct repeated mass chemotherapy, together with improvement of environment and sanitation, is important for initiating and achieving STH control in a developing community.

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Molecular and biochemical characterization of hemoglobinase, a cysteine proteinase, in Paragonimus westermani
Joon-Hyuck Choi, Jae-Hyuk Lee, Hak-Sun Yu, Hae-Jin Jeong, Jin Kim, Yeon-Chul Hong, Hyun-Hee Kong, Dong-Il Chung
Korean J Parasitol 2006;44(3):187-196.
Published online September 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.3.187

The mammalian trematode Paragonimus westermani is a typical digenetic parasite, which can cause paragonimiasis in humans. Host tissues and blood cells are important sources of nutrients for development, growth and reproduction of P. westermani. In this study, a cDNA clone encoding a 47 kDa hemoglobinase of P. westermani was characterized by sequencing analysis, and its localization was investigated immunohistochemically. The phylogenetic tree prepared based on the hemoglobinase gene showed high homology with hemoglobinases of Fasciola hepatica and Schistosoma spp. Moreover, recombinant P. westermani hemoglobinase degradaded human hemoglobin at acidic pH (from 3.0 to 5.5) and its activity was almost completely inhibited by E-64, a cysteine proteinase inhibitor. Immunohistochemical studies showed that P. westermani hemoglobinase was localized in the epithelium of the adult worm intestine implying that the protein has a specific function. These observations suggest that hemoglobinase may act as a digestive enzyme for acquisition of nutrients from host hemoglobin. Further investigations may provide insights into hemoglobin catabolism in P. westermani.

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Involvement of MAPK activation in chemokine or COX-2 productions by Toxoplasma gondii
Ji-Young Kim, Myoung-Hee Ahn, Hyun-Ouk Song, Jong-Hak Choi, Jae-Sook Ryu, Duk-Young Min, Myung-Hwan Cho
Korean J Parasitol 2006;44(3):197-207.
Published online September 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.3.197

This experiment focused on MAPK activation in host cell invasion and replication of T. gondii, as well as the expression of CC chemokines, MCP-1 and MIP-1α, and enzyme, COX-2/prostaglandin E2 (PGE2) in infected cells via western blot, [3H]-uracil incorporation assay, ELISA and RT-PCR. The phosphorylation of ERK1/2 and p38 in infected HeLa cells was detected at 1 hr and/or 6 hr postinfection (PI). Tachyzoite proliferation was reduced by p38 or JNK MAPK inhibitors. MCP-1 secretion was enhanced in infected peritoneal macrophages at 6 hr PI. MIP-1α mRNA was increased in macrophages at 18 hr PI. MCP-1 and MIP-1α were reduced after treatment with inhibitors of ERK1/2 and JNK MAPKs. COX-2 mRNA gradually increased in infected RAW 264.7 cells and the secretion of COX-2 peaked at 6 hr PI. The inhibitor of JNK suppressed COX-2 expression. PGE2 from infected RAW 264.7 cells was increased and synthesis was suppressed by PD98059, SB203580, and SP600125. In this study, the activation of p38, JNK and/or ERK1/2 MAPKs occurred during the invasion and proliferation of T. gondii tachyzoites in HeLa cells. Also, increased secretion and expression of MCP-1, MIP-1α, COX-2 and PGE2 were detected in infected macrophages, and appeared to occur via MAPK signaling pathways.

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Cytokine and antibody responses of reactivated murine toxoplasmosis upon administration of dexamethasone
Ki-Man Kang, In-Uk Choi, Dae-Whan Shin, Young-Ha Lee
Korean J Parasitol 2006;44(3):209-219.
Published online September 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.3.209

Toxoplasma gondii has been shown to result in life-threatening encephalitis in immunocompromised patients after reactivation of dormant parasites. In order to obtain information on immune responses related to this phenomenon, BALB/c mice were infected with 25 cysts of the 76K strain of T. gondii, then, treated orally with dexamethasone (Toxo/Dexa-treated group) in order to reactivate the chronic toxoplasmosis. None of the T. gondii-infected mice died during the experimental periods, whereas the Toxo/Dexa-treated mice evidenced a significant attenuation of survival periods. Toxoplasma-specific IgG2a, IgA and IgM titers in sera were significantly depressed in the Toxo/Dexa-treated mice; however, the IgG1 sera titers were similar to those seen in the Toxoplasma-infected mice. The percentages of CD4+ and CD8α+ T cells in the Toxo/Dexa-treated mice were significantly reduced 2 weeks after dexamethasone treatment. IFN-γ and IL-10 production levels in the Toxo/Dexa-treated mice were depressed significantly, whereas IL-4 production was increased temporarily. The expression levels of the Toxoplasma-specific P30 and B1 genes were found to have been increased in the Toxo/Dexa-treated mice in comparison with the Toxoplasma-infected mice. Collectively, the findings of this study demonstrate that reactivation of murine toxoplasmosis as the result of dexamethasone treatment induced a depression in Th1 immune responses, whereas Th2 immune responses were not significantly influenced.

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Safety and tolerability of elubaquine (bulaquine, CDRI 80/53) for treatment of Plasmodium vivax malaria in Thailand
Srivicha Krudsood, Polrat Wilairatana, Noppadon Tangpukdee, Kobsiri Chalermrut, Siripun Srivilairit, Vipa Thanachartwet, Sant Muangnoicharoen, Natthanej Luplertlop, Gary M. Brittenham, Sornchai Looareesuwan
Korean J Parasitol 2006;44(3):221-228.
Published online September 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.3.221

We conducted a study to compare the safety and tolerability of anti-relapse drugs elubaquine and primaquine against Plasmodium vivax malaria. After standard therapy with chloroquine, 30 mg/kg given over 3 days, 141 patients with P. vivax infection were randomized to receive primaquine or elubaquine. The 2 treatment regimens were primaquine 30 mg once daily for 7 days (group A, n = 71), and elubaquine 25 mg once daily for 7 days (group B, n = 70). All patients cleared parasitemia within 7 days after chloroquine treatment. Among patients treated with primaquine, one patient relapsed on day 26; no relapse occurred with elubaquine treatement. Both drugs were well tolerated. Adverse effects occurred only in patients with G6PD deficiency who were treated with primaquine (group A, n = 4), whose mean hematocrit fell significantly on days 7, 8 and 9 (P = 0.015, 0.027, and 0.048, respectively). No significant change in hematocrit was observed in patients with G6PD deficiency who were treated with elubaquine (group B, n = 3) or in patients with normal G6PD. In conclusion, elubaquine, as anti-relapse therapy for P. vivax malaria, was as safe and well tolerated as primaquine and did not cause clinically significant hemolysis.

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    Ilan Youngster, Lidia Arcavi, Renata Schechmaster, Yulia Akayzen, Hen Popliski, Janna Shimonov, Svetlana Beig, Matitiahu Berkovitch
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    J. Kevin Baird
    Clinical Microbiology Reviews.2009; 22(3): 508.     CrossRef
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Travelers' malaria among foreigners at the Hospital for Tropical Diseases, Bangkok, Thailand: a 6-year review (2000-2005)
Watcharapong Piyaphanee, Srivicha Krudsood, Udomsak Silachamroon, Karnchana Pornpininworakij, Phatcharee Danwiwatdecha, Supat Chamnachanan, Polrat Wilairatana, Sornchai Looareesuwan
Korean J Parasitol 2006;44(3):229-232.
Published online September 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.3.229

We retrospectively examined the charts of travelers admitted to the Hospital for Tropical Diseases, Bangkok, Thailand, with malaria during the years 2000-2005. Twenty-one cases of malaria were identified, of which 12 (57%) were Plasmodium vivax infections and 9 (43%) were P. falciparum infections. There was one mixed case with vivax and falciparum infection. Only 1 P. falciparum case had complications. All cases were successfully treated with standard antimalarial drugs. Only 3 of the 21 cases were thought to be acquired in Thailand, the rest were regarded to be imported.

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  • Epidemiologic trends and clinical outcomes of imported malaria in a tertiary care hospital, Bangkok, Thailand: A retrospective analysis (2013–2022)
    Panita Looareesuwan, Rachata Charoenwisedsil, Punyisa Asawapaithulsert, Phimphan Pisutsan, Viravarn Luvira, Watcharapong Piyaphanee, Wasin Matsee
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    Annelies Wilder-Smith
    Journal of Travel Medicine.2017;[Epub]     CrossRef
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    Saranath Lawpoolsri, Irwin F Chavez, Surapon Yimsamran, Supalap Puangsa-art, Nipon Thanyavanich, Wanchai Maneeboonyang, Wuthichai Chaimungkun, Pratap Singhasivanon, James H Maguire, Laura L Hungerford
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    Panita Gosi, Srisin Khusmith, Thareerat Khalambaheti, David E Lanar, Kurt E Schaecher, Mark M Fukuda, Scott R Miller
    Malaria Journal.2008;[Epub]     CrossRef
  • 7,939 View
  • 86 Download
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Brief Communications
Cloning of the novel putative apoptosis-related gene of Spirometra erinacei (Order Pseudophyllidea)
Soo-Ung Lee, Sun Huh
Korean J Parasitol 2006;44(3):233-237.
Published online September 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.3.233

We postulated that apolysis was processed in accordance with apoptotic changes occurring in a cestode, Spirometra erinacei (Pseudophyllidea). We cloned the novel putative apoptosis-associated gene from S. erinacei via screening of a S. erinacei cDNA library with a ced-3 gene (activator of apoptosis) probe from Caenorhabditis elegans. We identified a 261-bp cDNA sequence, which encodes for an 86-amino acid protein. The cloned gene expression was observed in the neck and gravid proglottids via Northern blotting, using cloned cDNA inserts as probes, but the clone was not expressed in any of other tissues. We suggest that this gene may be involved in the apolysis of S. erinacei during normal tissue development and differentiation in cestode parasites.

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  • The genome of the sparganosis tapeworm Spirometra erinaceieuropaeiisolated from the biopsy of a migrating brain lesion
    Hayley M Bennett, Hoi Ping Mok, Effrossyni Gkrania-Klotsas, Isheng J Tsai, Eleanor J Stanley, Nagui M Antoun, Avril Coghlan, Bhavana Harsha, Alessandra Traini, Diogo M Ribeiro, Sascha Steinbiss, Sebastian B Lucas, Kieren SJ Allinson, Stephen J Price, Thom
    Genome Biology.2014;[Epub]     CrossRef
  • 8,204 View
  • 56 Download
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In vitro protoscolicidal effects of hypertonic glucose on protoscolices of hydatid cyst
Seyed Vahid Hosseini, Kurosh Ghanbarzadeh, Zahra Barzin, Seyed Mahmoud Sadjjadi, Nader Tanideh, Davood Mehrabani
Korean J Parasitol 2006;44(3):239-242.
Published online September 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.3.239

To evaluate the protoscolicidal effects of various concentrations of hypertonic glucose, live protoscolices of sheep were exposed to 10%, 15%, 25% and 50% glucose solutions. Cetrimide (0.5%), silver nitrate (0.5%) and hypertonic saline (20%) were used as positive controls, while physiological saline was used as a negative control. After 1, 2 and 5 min, the protoscolicidal effects were determined by 1% eosin. A 25% glucose solution had no significant protoscolicidal effect. However, a 50% glucose solution revealed higher protoscolicidal effect than 0.5% silver nitrate but weaker effect than 0.5% cetrimide; the effect was comparable with that of 20% hypertonic saline. The results showed that hypertonic glucose solution is highly effective in killing protoscolices of Echinococcus granulosus in vitro.

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  • In Vitro Scolicidal Effect of Urtica dioica and Pyrus boissieriana Extracts Against Protoscoleces of Echinococcus granulosus
    Kimia Goudarzi, Rasoul Alimi, Tandis Zarghami, Mohammad Saleh Bahreini, Mohamad Ghanimatdan, Meysam Sharifdini, Erfan Kohansal, Aref Teimouri
    Shiraz E-Medical Journal.2024;[Epub]     CrossRef
  • Protoscolicidal effects of curcumin nanoemulsion against protoscoleces of Echinococcus granulosus
    Aref Teimouri, Sanaz Jafarpour Azami, Saeedeh Hashemi Hafshejani, Mohammad Ghanimatdan, Mohammad Saleh Bahreini, Rasoul Alimi, Seyed Mahmoud Sadjjadi
    BMC Complementary Medicine and Therapies.2023;[Epub]     CrossRef
  • Scorpion crude venom induced apoptosis and structural changes of Echinococcus granulosus protoscolices
    Esam S. Al-Malki, Manei M. Aljedaie, Omar S.O. Amer, Naser Abdelsater, Ahmed Badry
    Journal of King Saud University - Science.2022; 34(4): 101937.     CrossRef
  • In vitro protoscolicidal effects of lithocholic acid on protoscoleces of Echinococcus granulosus and its mechanism
    Ya Xu, Wenjuan Qing, Zhen Wang, Lin Chen, Linyao Wang, Hailong Lv, Yufeng Jiang
    Experimental Parasitology.2022; 239: 108280.     CrossRef
  • Anti-hydatidosis Potential of Sodium Valproate: Evaluating New Therapeutic Potential for Sodium Valproate
    Mohammadreza Rezaie, Reza Rahimi, Zahra Eslamirad
    Archives of Clinical Infectious Diseases.2022;[Epub]     CrossRef
  • Study on the effect of an ion channel inhibitor “Fluralaner” on Echinococcus granulosus protoscolices and metacestode layers in vitro
    Fatima Zahran, Hayam Mohamed Ezz El-Din, Mai Abdel Sameaa Shehata
    Journal of Parasitic Diseases.2020; 44(2): 411.     CrossRef
  • Echinococcus Granulosus in Childhood: A Retrospective Study of 187 Cases and Newer Data
    Anastasios S. Petropoulos, Georgios A. Chatzoulis
    Clinical Pediatrics.2019; 58(8): 864.     CrossRef
  • In-vitro evaluation of Nigella sativa and Punica granatum effect on protoscolices of hydatid cysts
    Nasr Moawad El-Bahy, Amer Ragheb Abdelaziz, Reda Elbastawisy Khalafalla
    Revista Brasileira de Parasitologia Veterinária.2019; 28(2): 210.     CrossRef
  • In Vitro Study on Protoscolicidal Effect of Methanolic Extract of Allium hirtifolium on Protoscoleces of Cystic Echinococcosis
    Z. Shahamir Tabatabaei, S. Dehshahri, M.M. Taghi, F. Esfandiari, F.S. Sadjjadi, M. Ebrahimipour, S.M. Sadjjadi
    Infectious Disorders - Drug Targets.2019; 19(3): 264.     CrossRef
  • Povidone iodine versus silver nitrate in induction of sclerosing cholangitis in hepatic hydatid cysts surgery
    Seyed Vahid Hosseini, Abdulrazzak Kalaf Hassan, Ahmed Mohamed Ali Hussein Alhurry, Maral Mokhtari, Nader Tanideh, Sepideh Sefidbakht, Hajar Khazraei
    Comparative Clinical Pathology.2018; 27(1): 239.     CrossRef
  • Solidification of hydatid cyst fluid with an injectable chitosan/carboxymethylcellulose/β-glycerophosphate hydrogel for effective control of spillage during aspiration of hydatid cysts
    Mostafa D. A. Azadi, Shadi Hassanjili, Khalil Zarrabi, Bahador Sarkari
    Progress in Biomaterials.2018; 7(1): 35.     CrossRef
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    Mar Siles-Lucas, Adriano Casulli, Roberto Cirilli, David Carmena, Giovanna Raso
    PLOS Neglected Tropical Diseases.2018; 12(4): e0006422.     CrossRef
  • Chemical composition and scolicidal activity of Zataria multiflora Boiss essential oil
    Hossein Mahmoudvand, Seyed Reza Mirbadie, Saeed Sadooghian, Majid Fasihi Harandi, Sareh Jahanbakhsh, Ebrahim Saedi Dezaki
    Journal of Essential Oil Research.2017; 29(1): 42.     CrossRef
  • Effects of trigonelline inhibition of the Nrf2 transcription factor in vitro on Echinococcus granulosus
    Wenjuan Qin, Dongfang Guan, Rongji Ma, Rentan Yang, Guoqiang Xing, Hongjuan Shi, Guangyao Tang, Jiajie Li, Hailong Lv, Yufeng Jiang
    Acta Biochimica et Biophysica Sinica.2017; 49(8): 696.     CrossRef
  • Scolicidal agents for protoscolices of Echinococcus granulosus hydatid cyst: Review of literature
    Seyedeh Maryam Sharafi, Raheleh Rafiei Sefiddashti, Behnam Sanei, Morteza Yousefi, Hossein Yousofi Darani
    Journal of Research in Medical Sciences.2017;[Epub]     CrossRef
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    Hossein Mahmoudvand, Farnaz Kheirandish, Ebrahim Saedi Dezaki, Saeedeh Shamsaddini, Majid Fasihi Harandi
    Biomedicine & Pharmacotherapy.2016; 82: 393.     CrossRef
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    Yosra Hussein Alam-Eldin, Abeer Fathy Badawy
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    Zahra Eslamirad, Homa Soleimani, Reza Hajihossein, Fatemeh Rafiei
    Asian Pacific Journal of Tropical Disease.2015; 5(10): 821.     CrossRef
  • Study of Protoscolicidal Effects of Hypertonic Glucose on Protoscolices of Hydatid Cyst at Different Concentrations and Exposure Times
    Mojtaba Shahnazi, Fatemeh Badakhsh, Abbas Azadmehr, Mehrzad Saraei, Mahmood Alipour, Maryam Shahnazi, Mehri Jamshidi
    International Scholarly Research Notices.2014; 2014: 1.     CrossRef
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    The Korean Journal of Parasitology.2014; 52(6): 653.     CrossRef
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    Mohammad Zibaei, Amanallah Sarlak, Bahram Delfan, Behrouz Ezatpour, Alireza Azargoon
    The Korean Journal of Parasitology.2012; 50(1): 53.     CrossRef
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  • Evaluation of Different Chemical Agents on the Germinative Layer of Sheep Hydatid Cyst After Implantation to Peritoneal Cavity of Balb/C
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    Journal of Investigative Surgery.2009; 22(3): 183.     CrossRef
  • In Vitro Screening of DifferentAllium SativumExtracts on Hydatid Cysts Protoscoleces
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  • In Vitro Effectiveness of Different Chemical Agents on Scolices of Hydatid Cyst
    Recep Caglar, Mehmet Fatih Yuzbasioglu, Ertan Bulbuloglu, Mustafa Gul, Fikret Ezberci, Ilhami Taner Kale
    Journal of Investigative Surgery.2008; 21(2): 71.     CrossRef
  • 9,116 View
  • 82 Download
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Infection status of pond smelts, Hypomesus olidus, and other freshwater fishes with trematode metacercariae in 6 large lakes
Shin-Hyeong Cho, Woon-Mok Sohn, Sung-Shik Shin, Hyeon-Je Song, Taek-Gyun Choi, Chang-Mi Oh, Yoon Kong, Tong-Soo Kim
Korean J Parasitol 2006;44(3):243-246.
Published online September 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.3.243

In order to determine the current infection status of pond smelts, Hypomesus olidus, and other freshwater fishes with trematode metacercariae, a total of 4,861 pond smelts and 18 other freshwater fishes, collected from the Soyang and Uiam Lakes in Gangwon-do, the Unam Lake in Jeollabuk-do, the Jangseong Lake in Jeollanam-do, the Uirim-ji (lake) in Chungcheongbuk-do, and the Andong Lake in Gyeongsangbuk-do, were individually digested with 1% pepsin-HCl and examined under a dissecting microscope. In all pond smelts caught from the 6 lakes, we were unable to detect any known human infectious trematode metacercariae in Korea. However, in other freshwater fishes, such as, Squalidus japonicus coreanus (Unam Lake), and Zacco platypus (Jangseong Lake) and Opsariichthys uncirostris amurensis (Jangseong Lake), metacercariae of human-infecting trematodes, i.e., Clonorchis sinensis and Metagonimus sp. were detected, respectively.

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  • Ultrasound-Assisted Enhancement of Gel Properties in Hypomesus olidus Surimi
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    Yuan Fu, Chuanhao Liu, Xiaohui Yan, Guochuan Jiang, Qiao Dang, Liyan Wang, Xuejun Liu
    Food Chemistry: X.2022; 16: 100484.     CrossRef
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    Xuan Zhang, Xin‐Tong Ma, Yu Xu, Guo‐Chuan Jiang, Jia‐Lin Zhang, Xue‐Jun Liu, Xiao‐Hui Yan
    Food Science & Nutrition.2020; 8(2): 849.     CrossRef
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    Young-Il Lee, Min Seo, Jong-Yil Chai
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    Journal of the Korean earth science society.2020; 41(2): 129.     CrossRef
  • Prevalence of Clonorchis sinensis infection in freshwater fishes in northeastern China
    Y. Zhang, Q.C. Chang, Y. Zhang, L. Na, W.T. Wang, W.W. Xu, D.Z. Gao, Z.X. Liu, C.R. Wang, X.Q. Zhu
    Veterinary Parasitology.2014; 204(3-4): 209.     CrossRef
  • Prevalence ofClonorchis sinensisMetacercariae in Freshwater Fish from Three Latitudinal Regions of the Korean Peninsula
    Shin-Hyeong Cho, Woon-Mok Sohn, Byoung-Kuk Na, Tong-Soo Kim, Yoon Kong, Keeseon Eom, Won-Seok Seok, Taejoon Lee
    The Korean Journal of Parasitology.2011; 49(4): 385.     CrossRef
  • Infection Status of Freshwater Fish with Metacercariae of Clonorchis sinensis in Korea
    Eun-Min Kim, Jae-Lip Kim, Sung Yil Choi, Jae-Whan Kim, Siwon Kim, Min-Ho Choi, Young Mee Bae, Soon-Hyung Lee, Sung-Tae Hong
    The Korean Journal of Parasitology.2008; 46(4): 247.     CrossRef
  • Survey for zoonotic liver and intestinal trematode metacercariae in cultured and wild fish in An Giang Province, Vietnam
    Nguyen Diem Thu, Anders Dalsgaard, Ly Thi Thanh Loan, K. Darwin Murrell
    The Korean Journal of Parasitology.2007; 45(1): 45.     CrossRef
  • 8,324 View
  • 79 Download
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Egg positive rate of Enterobius vermicularis among preschool children in Cheongju, Chungcheongbuk-do, Korea
Seokha Kang, Hyeong Kyu Jeon, Keeseon S. Eom, Joong-Ki Park
Korean J Parasitol 2006;44(3):247-249.
Published online September 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.3.247

In an attempt to determine the prevalence of pinworm infection, the egg positive rate of Enterobius vermicularis was examined using the adhesive cello-tape anal swab method in 1,512 preschool children sampled from a total of 20 kindergartens in Cheongju city, in November to December of 2004 (951 children from 13 kindergartens) and September to October of 2005 (561 from 7 kindergartens). The overall egg positive rate was found to be 7.9% (119/1,512); 9.3% (73/784) for boys and 6.3% (46/728) for girls, respectively. The 5-year age group evidenced the highest egg positive rate (10.9%, 47/430) among the examined age groups. As compared to those reported from previous works (ranged from 9.2 to 26.1%), the prevalence of E. vermicularis in the Cheongju city area is relatively low.

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    Fanzhen Mao, Xiangzhen Xu, Feng Tang, Bixian Ni, Qiang Zhang, Jiayao Zhang, Yaobao Liu, You Li, Jun Cao
    BMC Public Health.2025;[Epub]     CrossRef
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  • Enterobius vermicularis Infection in a Child Population with Evidence of Vulvovaginitis and Bacterial Coinfection in Girls in Oaxaca, México
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    Advances in Public Health.2024;[Epub]     CrossRef
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    Osong Public Health and Research Perspectives.2023; 14(6): 441.     CrossRef
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    Abdulelah H. Al-Adhroey, Yahya A. Al-Ansi, Mohammed A. Al-Kholani, Abdulrahman H. Amer, Marwan M. Al-Khyat, Fadia H. Al Hubaishi, Radhwan H. Aziz, Ebrahim S. Al-Khateeb, Souad A. Al-Gabri, Tawfik M. Al-Gabri
    Journal of Parasitic Diseases.2022; 46(3): 722.     CrossRef
  • Enterobius vermicularis Infection among Preschool Children: A 12-Year (2008-2019) Survey in Large Cities and Provinces of the Republic of Korea
    Hyejoo Shin, Bong-Kwang Jung, Seungwan Ryoo, Sooji Hong, Taehee Chang, Jiyeon Park, Keon Hoon Lee, Jeonggyu Lee, Jae Young Park, Hoo-Gn Jeoung, Jae Hyun Cho, Jong-Yil Chai
    The Korean Journal of Parasitology.2021; 59(4): 421.     CrossRef
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    Ali Taghipour, Meysam Olfatifar, Ehsan Javanmard, Mojtaba Norouzi, Hamed Mirjalali, Mohammad Reza Zali, Paulo Lee Ho
    PLOS ONE.2020; 15(4): e0232143.     CrossRef
  • A preliminary epidemiological study of pinworm infection in Thaklong Municipal Early Childhood Development Center and Rangsit Babies’ Home, Pathum Thani, Thailand
    Aree Taylor, Prasert Saichua, Pochong Rhongbutsri, Rattana Tiengtip, Sirima Kitvatanachai, Walter R. J. Taylor
    BMC Research Notes.2018;[Epub]     CrossRef
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    A. Dudlová, P. Juriš, P. Jarčuška, Z. Vasilková, V. Vargová, M. Sumková, V. Krčméry
    Helminthologia.2018; 55(4): 275.     CrossRef
  • Pinworm (Enterobius vermicularis) Infection among Primary Level Government School Children of Chhampi, Lalitpur District, Nepal
    Karuna Khadka, Mahendra Maharjan
    National Journal of Health Sciences.2018; 3(2): 46.     CrossRef
  • Prevalence ofEnterobius vermicularisamong Children in Iran: A Systematic Review and Meta-analysis
    Mahmood Moosazadeh, Ghasem Abedi, Mahdi Afshari, Seif Ali Mahdavi, Fereshteh Farshidi, Elham Kheradmand
    Osong Public Health and Research Perspectives.2017; 8(2): 108.     CrossRef
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    Seyed Ali Norbakhsh Amiri, Mohammad Taghi Rahimi, Seif Ali Mahdavi, Mahmood Moosazadeh, Omid Ramzani, Ali Farrokhi Koshk, Reza Rosbehan, Seyed Abolghasem Siyadatpanah
    Journal of Parasitic Diseases.2016; 40(4): 1558.     CrossRef
  • Prevalence of Enterobius vermicularis Among Children in Kindergartens and Primary Schools in Iran: A Systematic Review and Meta-Analysis
    Mahmood Moosazadeh, Ghasem Abedi, Mahdi Afshari, Seif Ali Mahdavi, Fereshteh Farshidi, Elham Kheradmand
    Osong Public Health and Research Perspectives.2016;[Epub]     CrossRef
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    Dong-Hee Kim, Hak Sun Yu, David Joseph Diemert
    PLoS ONE.2014; 9(11): e112149.     CrossRef
  • Clinical Update on Parasitic Diseases
    Min Seo
    Korean Journal of Medicine.2013; 85(5): 469.     CrossRef
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    Dong-Hee Kim, Min Kyoung Cho, Mi Kyung Park, Shin Ae Kang, Bo Young Kim, Sang Kyun Park, Hak Sun Yu
    The Korean Journal of Parasitology.2013; 51(1): 139.     CrossRef
  • REPEATED URETHRITIS DUE TO ENTEROBIUS VERMICULARIS-A CASE REPORT
    Vimal Rathod, Sharmila Raut, Sanjay Rajaram More, Poonam Sharma, Vidya Nardele, Vaibhav Rajhans
    Journal of Evolution of medical and Dental Sciences.2013; 2(4): 392.     CrossRef
  • Prevalence of Enterobius vermicularis among Preschool Children in Muan-gun, Jeollanam-do, Korea
    Sung-Hee Hong, Young-Il Jeong, Jin-Hee Lee, Shin-Hyeong Cho, Won-Ja Lee, Sang-Eun Lee
    The Korean Journal of Parasitology.2012; 50(3): 259.     CrossRef
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    In-Soon Kang, Dong-Hee Kim, Hye-Gyung An, Hyun-Mi Son, Min Kyoung Cho, Mi-Kyung Park, Shin Ae Kang, Bo Young Kim, Hak Sun Yu
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Molecular cloning of a rhoptry protein (ROP6) secreted from Toxoplasma gondii
Hye-Jin Ahn, Sehra Kim, Ho-Woo Nam
Korean J Parasitol 2006;44(3):251-254.
Published online September 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.3.251

Monoclonal antibody (mAb) Tg786 against Toxoplasma gondii has been found to detect a 42-kDa rhoptry protein (ROP6) which showed protease activity and host cell binding characteristics after secretion. Using the mAb, a colony containing a 3'-UTR was probed in a T. gondii cDNA expression library. A full length cDNA sequence of the rhoptry protein was completed after 5'-RACE, which consisted of 1,908 bp with a 1,443 bp ORF. The deduced amino acid sequence of ROP6 consisted of a polypeptide of 480 amino acids without significant homology to any other known proteins. This sequence contains an amino terminal stop transfer sequence downstream of a short neutral sequence, hydrophilic middle sequence, and hydrophobic carboxy terminus. It is suggested that the ROP6 is inserted into the rhoptry membrane with both N- and C-termini.

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  • A systematic review of Toxoplasma gondii antigens to find the best vaccine candidates for immunization
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    Microbiological Research.2019;[Epub]     CrossRef
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    Fatemeh Rezaei, Mahdi Sharif, Shahabeddin Sarvi, Seyed Hossein Hejazi, Sargis Aghayan, Abdol Sattar Pagheh, Samira Dodangeh, Ahmad Daryani
    Journal of Microbiological Methods.2019; 165: 105696.     CrossRef
  • Rhoptry protein 6 from Toxoplasma gondii is an intrinsically disordered protein
    Won-Kyu Lee, Hye-Jin Ahn, Yeon Gyu Yu, Ho-Woo Nam
    Protein Expression and Purification.2014; 101: 146.     CrossRef
  • Electrophoretic Patterns of Toxoplasma gondii Excreted/Secreted Antigens and Their Role in Induction of the Humoral Immune Response
    Ahmad Daryani, Mehdi Sharif, Hamed Kalani, Alireza Rafiei, Farzad Kalani, Ehsan Ahmadpour
    Jundishapur Journal of Microbiology.2014;[Epub]     CrossRef
  • Kiss and spit: the dual roles of Toxoplasma rhoptries
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    Acta Biochimica et Biophysica Sinica.2007; 39(7): 475.     CrossRef
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Field trial on the control effect of fipronil bait against German cockroaches
Han-Il Ree, In-Yong Lee, Soung-Hoo Jeon, Tai-Soon Yong
Korean J Parasitol 2006;44(3):255-257.
Published online September 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.3.255

A field trial on the control effect of fipronil poison bait against German cockroaches (Blatella germanica) was carried out at different restaurant types in Sinchon, Seoul, Republic of Korea. Monitoring was performed applying food baited traps for 2 days per week. Reduction rates of German cockroaches by applying fipronil baits were 90.9% at Korean restaurants, 96.4% at Chinese restaurants, and 89.4% in beer hall kitchens after 4 weeks of the treatment. Overall average of the reduction rate was 93.9%. As the natural reduction rate at untreated restaurants was 11.5% after 4 weeks, a correction of the average reduction rate by applying the Abbot formula was 93.1%.

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    Japanese Journal of Applied Entomology and Zoology.2007; 51(2): 129.     CrossRef
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House dust mite fauna in western Anatolia, Turkey
Ihsan Hakki Ciftci, Zafer Cetinkaya, Metin Atambay, Nilay Kiyildi, Ozlem M. Aycan, Nilgun Daldal
Korean J Parasitol 2006;44(3):259-264.
Published online September 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.3.259

House dust mites play an important role in the pathogenesis of allergic diseases. Many factors may influence mite growth. The presence of mites is related to mean temperature and humidity as well as altitude. The aim of this study was to analyze the mite fauna in 5 regions of western Anatolia, Turkey, that have similar climatic properties with low mean temperature and humidity, but differ in altitude. During the period October-November 2004, house dust was collected from 290 homes in 5 different cities. House dust mites were isolated in 67 (23.1%) of 290 samples. The family Pyroglyphidae (Astigmata) was present in all positive samples. This study suggests that the selected western Anatolian regions that share similar environmental conditions host similar dust mite populations.

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    M. Aykut, O. K. Erman, S. Doğan
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  • High Sensitization to House-Dust Mites in Patients with Allergic Rhinitis in the Eastern Black Sea Region of Turkey: A Retrospective Study
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  • Incrimination of Blomia tropicalis as a Potent Allergen in House Dust and its Role in Allergic Asthma in Kolkata Metropolis, India
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    World Allergy Organization Journal.2010; 3(5): 182.     CrossRef
  • Seasonal prevalence of allergenic mites in house dust of Kolkata Metropolis, India
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    Experimental and Applied Acarology.2007; 42(1): 55.     CrossRef
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Status of intestinal helminthic infections of borderline residents in North Korea
Shunyu Li, Chenghua Shen, Min-Ho Choi, Young Mee Bae, Hiwon Yoon, Sung-Tae Hong
Korean J Parasitol 2006;44(3):265-268.
Published online September 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.3.265

The present authors investigated intestinal parasitic infections among North Korean residents and refugees in China in 2003. The Kato-Katz method was applied to 236 residents and soldiers in a town on the North Korea-China border and to 46 people at a refugee camp in China. Only eggs of Ascaris and Trichuris were detected, with egg positive rates of 41.1% and 37.6%, respectively. The total egg positive rate was 55.0% and most of those who were egg positive were only lightly infected. Women of 61.2% and men of 53.1% were egg positive. The refugees from rural areas showed higher egg positive rates than those from urban areas. The present investigation confirmed high prevalence of soil-transmitted intestinal helminths in rural borderline areas of North Korea.

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