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Volume 59(4); August 2021

Original Articles

Electrophysiological Properties of Ion Channels in Ascaris suum Tissue Incorporated into Planar Lipid Bilayers
Kwon Moo Park, Sun-Don Kim, Jin Bong Park, Sung-Jong Hong, Pan Dong Ryu
Korean J Parasito 2021;59(4):329-339.
Published online August 18, 2021
DOI: https://doi.org/10.3347/kjp.2021.59.4.329
Ion channels are important targets of anthelmintic agents. In this study, we identified 3 types of ion channels in Ascaris suum tissue incorporated into planar lipid bilayers using an electrophysiological technique. The most frequent channel was a large-conductance cation channel (209 pS), which accounted for 64.5% of channels incorporated (n=60). Its open-state probability (Po) was ~0.3 in the voltage range of –60~+60 mV. A substate was observed at 55% of the main-state. The permeability ratio of Cl- to K+ (PCl/PK) was ~0.5 and PNa/PK was 0.81 in both states. Another type of cation channel was recorded in 7.5% of channels incorporated (n=7) and discriminated from the large-conductance cation channel by its smaller conductance (55.3 pS). Its Po was low at all voltages tested (~0.1). The third type was an anion channel recorded in 27.9% of channels incorporated (n=26). Its conductance was 39.0 pS and PCl/PK was 8.6±0.8. Po was ~1.0 at all tested potentials. In summary, we identified 2 types of cation and 1 type of anion channels in Ascaris suum. Gating of these channels did not much vary with voltage and their ionic selectivity is rather low. Their molecular nature, functions, and potentials as anthelmintic drug targets remain to be studied further.
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Acanthoparyphium shinanense n. sp. (Digenea: Echinostomatidae) from Experimental Chicks Infected with Metacercariae Encysted in Brackish Water Clams in the Republic of Korea
Seungwan Ryoo, Bong-Kwang Jung, Taehee Chang, Sooji Hong, Hyejoo Shin, Jong-Yil Chai
Korean J Parasito 2021;59(4):341-353.
Published online August 18, 2021
DOI: https://doi.org/10.3347/kjp.2021.59.4.341
Acanthoparyphium shinanense n. sp. (Digenea: Echinostomatidae) is described from chicks experimentally infected with the metacercariae encysted in 2 brackish water clam species, Ruditapes philippinarum and Coecella chinensis, in the Republic of Korea. The metacercariae were round to oval, armed with 23 collar spines, and 0.216 (0.203-0.226) mm in diameter. From 5 chicks experimentally infected each with 200 metacercariae, 34 juvenile (5-day-old worms) and 104 adult flukes (7-day-old worms) were harvested from their small intestines, with the average worm recovery rate of 13.8%. The adult flukes were 3.18 (2.89-3.55) mm long and 0.68 (0.61-0.85) mm wide, with an elongated, posteriorly tapering body, and a prominent head collar armed with 23 collar spines arranged in a single uninterrupted row. The posterior testis of A. shinanense was longitudinally elongated, which is similar to Acanthoparyphium spinulosum Johnston, 1917 but unique from the other closely related species, including Acanthoparyphium tyosenense Yamaguti, 1939, Acanthoparyphium kurogamo Yamaguti, 1939, and Acanthoparyphium marilae Yamaguti, 1934. The eggs of A. shinanense were larger than those of A. spinulosum, and the anterior extent of 2 lateral groups of vitellaria was slightly more limited in A. shinanense than in A. spinulosum. Molecular analysis of nuclear and mitochondrial genes revealed low homology with A. spinulosum from USA (96.1% in 5.8S rRNA) and Ukraine (97.9% in 28S rRNA), Acanthoparyphium n. sp. from USA (98.0% in 28S rRNA), and Acanthoparyphium sp. from Australia, Kuwait, and New Zealand. Biological characteristics, including its first intermediate host and natural definitive hosts, as well as its zoonotic capability, should be elucidated.

Citations

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  • Supplemental Description of Caballerotrema annulatum (Diesing, 1850) Ostrowski de Núñez and Sattmann, 2002 (Digenea: Caballerotrematidae) from a New Host (Electrophorus Cf. Varii) and Locality (Amazon River, Colombia) with Phylogenetic Analysis and Emende
    Kamila Cajiao-Mora, John H. Brule, Haley R. Dutton, Stephen A. Bullard
    Journal of Parasitology.2024;[Epub]     CrossRef
  • 4,918 View
  • 123 Download
  • 1 Web of Science
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Morphology and Mitochondrial Genome of Fischoederius sp. 1 in Thailand
Pichanee Watthanasiri, Amornrat Geadkaew-Krenc, Rudi Grams
Korean J Parasito 2021;59(4):355-362.
Published online August 18, 2021
DOI: https://doi.org/10.3347/kjp.2021.59.4.355
A rumen fluke Fischoederius elongatus is assigned to the type species of genus Fischoederius, family Gastrothylacidae. However, the mitochondrial sequences recently published are thought to be of inconsistent species, suggesting that several morphologically similar but genetically distinct species might be classified as Fischoederius elongatus. Thus, mentions of F. elongatus from South, Southeast, and East Asia might unintentionally refer to different species. The present work describes morphology and a full mitochondrial genome sequence of one of these species. The fluke specimens were collected from 2 infected cattle in Thailand. An interesting finding was the presence of a second tRNA-Asp gene next to a partial ND1 gene. It is suggested that these duplicated sequences are the remnants of non-reciprocal recombination events caused by inverted repeats located between ND2 and ND1 mitochondrial genes.

Citations

Citations to this article as recorded by  Crossref logo
  • Morphological Observation and Detailed Molecular Characterization of Fischoederius elongatus (Digenea: Gastrothylacidae) from the Rumen of Domestic Cattle in Cambodia
    Chinda Wann, Bengthay Tep, Witaya Suriyasathaporn, Yasuhiro Morita, Vutha Pheng, Satoshi Ohkura, Shuichi Matsuyama, Sho Nakamura, Kei Hayashi
    Journal of Parasitology.2025;[Epub]     CrossRef
  • The complete mitochondrial genome of Aspidogaster ijimai (Platyhelminthes: Trematoda: Aspidogastrea): gene content and phylogenetic inference
    D. A. Solodovnik, D. M. Atopkin, A. A. Semenchenko, M. Urabe, S. G. Sokolov
    Invertebrate Zoology.2025; 22(3): 411.     CrossRef
  • Differentiating paramphistome species in cattle using DNA barcoding coupled with high-resolution melting analysis (Bar-HRM)
    Kittisak Buddhachat, Sirikhwan Sriuan, Sirapat Nak-on, Thapana Chontananarth
    Parasitology Research.2023; 122(3): 769.     CrossRef
  • The determination and relationship of four coexisting paramphistomes in perspective of integrative taxonomic investigation
    Sirapat Nak-on, Thapana Chontananarth
    Veterinary Parasitology: Regional Studies and Reports.2023; 40: 100849.     CrossRef
  • 6,558 View
  • 107 Download
  • 3 Web of Science
  • Crossref
Helicobacter pylori GroEL Seropositivity Is Associated with an Increased Risk of Opisthorchis viverrini-Associated Hepatobiliary Abnormalities and Cholangiocarcinoma
Isabelle Jala, Muhammad Luthfi Almanfaluthi, Thewarach Laha, Sakawrat Kanthawong, Sirikachorn Tangkawattana, Prasert Saichua, Sutas Suttiprapa, Banchob Sripa
Korean J Parasito 2021;59(4):363-368.
Published online August 18, 2021
DOI: https://doi.org/10.3347/kjp.2021.59.4.363
Despite the synergistic effect of Opisthorchis viverrini and Helicobacter pylori co-infection on pathogenesis of severe hepatobiliary abnormalities (HBA) including advanced periductal fibrosis and replace with cholangiocarcinoma (CCA) have been established, the immune response to H. pylori in O. viverrini infected population has never been explored. Hence, this study aimed to investigate the antibody responses to 2 immunogenic H. pylori proteins in O. viverrini-infected patients with HBA and CCA. The risk analysis by multinomial logistic regression revealed that GroEL seropositivity was associated with higher risks of hepatobiliary abnormalities and CCA with adjusted odds ratios (95% confidence intervals) of 2.11 (95% CI=1.20-3.71, P=0.008) and 2.13 (95% CI=1.21-3.75, P=0.009), respectively. These findings indicate that GroEL seropositivity might be a biomarker for early detection of O. viverrini associated HBA and CCA.

Citations

Citations to this article as recorded by  Crossref logo
  • Helicobacter Species and Hepato-Biliary Tract Malignancies: A Systematic Review and Meta-Analysis
    Beatriz Gros, Alberto Gómez Pérez, María Pleguezuelo, Francisco Javier Serrano Ruiz, Manuel de la Mata, Manuel Rodríguez-Perálvarez
    Cancers.2023; 15(3): 595.     CrossRef
  • New challenges in cholangiocarcinoma candidates for elective surgery: harnessing the microbiome dysbiosis
    Oriana Lo Re, Victor López-López, Andrés Balaguer-Román, María Antonia Martínez-Sánchez, Dilmurodjon Eshmuminov, Camilo Julio Llamoza-Torres, Kohei Miura, Alberto Baroja-Mazo, Pablo Ramírez, Ricardo Robles-Campos, Bruno Ramos-Molina
    Langenbeck's Archives of Surgery.2023;[Epub]     CrossRef
  • Opisthorchis viverrini—Current Understanding of the Neglected Hepatobiliary Parasite
    Matthias Yi Quan Liau, En Qi Toh, Vishalkumar Girishchandra Shelat
    Pathogens.2023; 12(6): 795.     CrossRef
  • The possible role of Helicobacter pylori in liver diseases
    Mahnaz Mohammadi, Adeleh Attar, Maryam Mohammadbeigi, Amir Peymani, Shahin Bolori, Fatemeh Fardsanei
    Archives of Microbiology.2023;[Epub]     CrossRef
  • Intestinal helminth infections and associated risk factors among adults in the Lao People’s Democratic Republic
    Sengaloun Phonekeo, Sengchanh Kounnavong, Manithong Vonglokham, Latsamy Siengsounthone, Anousin Homsana, Sascha Gummin, Penelope Vounatsu, Prawat Nittiyanant, Suchin Worawichawong, Wichai Aekplakorn, Peter Odermatt, Somphou Sayasone
    Infectious Diseases of Poverty.2023;[Epub]     CrossRef
  • Regulation in the Expression of Virulence Factors of Helicobacter pylori by the Interaction between AGS Cells and H. pylori
    Yu-Ri Kim, Wongwarut Boonyanugomol, Won-jun An, Trinh Minh Phuong, Jin-Sik Park, Min-Kyoung Shin, Seung-Chul Baik, Woo-Kon Lee, Myung-Je Cho, Hyung-Lyun Kang, Myunghwan Jung
    Journal of Bacteriology and Virology.2022; 52(4): 160.     CrossRef
  • 4,842 View
  • 88 Download
  • 5 Web of Science
  • Crossref
Human Taeniasis and Cysticercosis and Related Factors in Phu Tho Province, Northern Vietnam
Vu Thi Lam Binh, Do Trung Dung, Hoang Quang Vinh, Van Hul Anke, Praet Nicolas, Dorny Pierre, Dermauw Veronique
Korean J Parasito 2021;59(4):369-376.
Published online August 18, 2021
DOI: https://doi.org/10.3347/kjp.2021.59.4.369
Several factors presumed to facilitate the transmission of Taenia spp. were reported in Vietnam. We conducted a cross-sectional study taking questionnaires from 1,185 participants, and collecting 1,151 sera and 1,036 stool samples in northern Vietnam. Sera were examined for circulating antigens of Taenia solium cysticerci using ELISA, stools for Taenia eggs by Kato-Katz smear, and copro-antigens by ELISA. Ag-ELISA revealed 4.6% antigen positivity, indicating infection with viable cysticerci. Taenia eggs were detected in 1.5% of participants. Copro-antigens were found in 2.8% of participants. Eating raw meat and/or vegetables was significantly associated with the presence of copro-antigen (OR=8.6, 95% CI: 1.16-63.9, P=0.01). Considering the high taeniasis prevalence and the associated threat, public health attention should be given to treat the tapeworm carriers in the projected areas.

Citations

Citations to this article as recorded by  Crossref logo
  • The burden of T. solium cysticercosis and selected neuropsychiatric disorders in Mocuba district, Zambézia province, Mozambique
    Irene Langa, Fernando Padama, Noémia Nhancupe, Alberto Pondja, Delfina Hlashwayo, Lidia Gouveia, Dominik Stelzle, Clarissa Prazeres da Costa, Veronika Schmidt, Andrea S. Winkler, Emília Virgínia Noormahomed, Eduardo Torres
    PLOS Neglected Tropical Diseases.2022; 16(7): e0010606.     CrossRef
  • 5,557 View
  • 87 Download
  • 1 Web of Science
  • Crossref
Infestation and Related Ecology of Chigger Mites on the Asian House Rat (Rattus tanezumi) in Yunnan Province, Southwest China
Fan Ding, Wen-Li Jiang, Xian-Guo Guo, Rong Fan, Cheng-Fu Zhao, Zhi-Wei Zhang, Ke-Yu Mao, Rong Xiang
Korean J Parasito 2021;59(4):377-392.
Published online August 18, 2021
DOI: https://doi.org/10.3347/kjp.2021.59.4.377
This paper is to illustrate the infestation and related ecological characteristics of chigger mites on the Asian house rat (Rattus tanezumi). A total of 17,221 chigger mites were collected from 2,761 R. tanezumi rats, and then identified as 131 species and 19 genera in 2 families. Leptotrombidium deliense, the most powerful vector of scrub typhus in China, was the first major dominant species on R. tanezumi. All the dominant mite species were of an aggregated distribution among different individuals of R. tanezumi. The species composition and infestations of chiggers on R. tanezumi varied along different geographical regions, habitats and altitudes. The species-abundance distribution of the chigger mite community was successfully fitted and the theoretical curve equation was Ŝ (R)=37e–(0.28R)2. The total chigger species on R. tanezumi were estimated to be 199 species or 234 species, and this further suggested that R. tanezumi has a great potential to harbor abundant species of chigger mites. The results of the species-plot relationship indicated that the chigger mite community on R. tanezumi in Yunnan was an uneven community with very high heterogeneity. Wide geographical regions with large host samples are recommended in the investigations of chigger mites.

Citations

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  • Meteorological factors and normalized difference vegetation index drivers of scrub typhus incidence in Shandong Province based on a 16-year time-frequency analysis
    Zhisong Ni, Shufen Li, Rui Xi, Kemeng Liang, Sihao Song, Chuanlong Cheng, Hui Zuo, Liang Lu, Xiujun Li
    BMC Public Health.2025;[Epub]     CrossRef
  • Mite Infestation on Rattus tanezum rats in southwest China concerning risk models
    Ru-Jin Liu, Xian-Guo Guo, Pei-Ying Peng, Yan Lv, Peng-Wu Yin, Wen-Yu Song, Rong Xiang, Yan-Ling Chen, Bei Li, Dao-Chao Jin
    Frontiers in Veterinary Science.2025;[Epub]     CrossRef
  • Abundance and Infestation of Mites on Bower’s White-Toothed Rat (Berylmys bowersi) in Southwest China
    Chenxi Liu, Xianguo Guo, Yan Lv, Pengwu Yin, Wenyu Song, Peiying Peng, Rong Xiang, Yanling Chen, Bei Li
    Veterinary Sciences.2025; 12(5): 426.     CrossRef
  • The Association Between Environmental Factors and Scrub Typhus: A Review
    Shu Yang, Shu Yang, Yuxiang Xie, Wenjing Duan, Yiting Cui, Ai Peng, Yisheng Zhou, Yibing Fan, Hui Li, Peng Huang
    Tropical Medicine and Infectious Disease.2025; 10(6): 151.     CrossRef
  • Variation in Small Mammal Species Composition and the Occurrence of Parasitic Mites in Two Landscapes in a Scrub Typhus Endemic Region of Western Yunnan Province, China
    Yun‐Yan Luo, Jia‐Xiang Yin, Zong‐Ti Shao, Zeng‐Kan Liu, Shou‐Qin Yin, Jiang‐Li Lu, Jin‐Chun Li, Rong Wei, Alan Frederick Geater
    Ecology and Evolution.2025;[Epub]     CrossRef
  • The Distribution and Host-Association of the Vector Chigger Species Leptotrombidium imphalum in Southwest China
    Qiao-Yi Liu, Rong Fan, Wen-Yu Song, Pei-Ying Peng, Ya-Fei Zhao, Dao-Chao Jin, Xian-Guo Guo
    Insects.2024; 15(7): 504.     CrossRef
  • Estimation of scrub typhus incidence and spatiotemporal multicomponent characteristics from 2016 to 2023 in Zhejiang Province, China
    Haocheng Wu, Ming Xue, Chen Wu, Qinbao Lu, Zheyuan Ding, Xinyi Wang, Tianyin Fu, Ke Yang, Junfen Lin
    Frontiers in Public Health.2024;[Epub]     CrossRef
  • A Retrospective Report on the Infestation and Distribution of Chiggers on an Endemic Rodent Species (Apodemus latronum) in Southwest China
    Qiao-Yi Liu, Xian-Guo Guo, Rong Fan, Wen-Yu Song, Pei-Ying Peng, Ya-Fei Zhao, Dao-Chao Jin
    Veterinary Sciences.2024; 11(11): 547.     CrossRef
  • An Ecological Survey of Chiggers (Acariformes: Trombiculidae) Associated with Small Mammals in an Epidemic Focus of Scrub Typhus on the China–Myanmar Border in Southwest China
    Ru-Jin Liu, Xian-Guo Guo, Cheng-Fu Zhao, Ya-Fei Zhao, Pei-Ying Peng, Dao-Chao Jin
    Insects.2024; 15(10): 812.     CrossRef
  • Infestation of Oriental House Rat (Rattus tanezumi) with Chigger Mites Varies along Environmental Gradients across Five Provincial Regions of Southwest China
    Yan-Ling Chen, Xian-Guo Guo, Fan Ding, Yan Lv, Peng-Wu Yin, Wen-Yu Song, Cheng-Fu Zhao, Zhi-Wei Zhang, Rong Fan, Pei-Ying Peng, Bei Li, Ting Chen, Dao-Chao Jin
    International Journal of Environmental Research and Public Health.2023; 20(3): 2203.     CrossRef
  • Infestation and distribution of chigger mites on Chevrieri's field mouse (Apodemus chevrieri) in Southwest China
    Yan-Ling Chen, Xian-Guo Guo, Tian-Guang Ren, Lei Zhang, Rong Fan, Cheng-Fu Zhao, Zhi-Wei Zhang, Ke-Yu Mao, Xiao-Bin Huang, Ti-Jun Qian
    International Journal for Parasitology: Parasites and Wildlife.2022; 17: 74.     CrossRef
  • Infestation of chigger mites on Chinese mole shrew,Anourosorex squamipes, in Southwest China and ecological analysis
    Bei Li, Xian-Guo Guo, Cheng-Fu Zhao, Zhi-Wei Zhang, Rong Fan, Pei-Ying Peng, Wen-Yu Song, Tian-Guang Ren, Lei Zhang, Ti-Jun Qian
    Parasite.2022; 29: 39.     CrossRef
  • Analysis on infestation and related ecology of chigger mites on large Chinese voles (Eothenomys miletus) in five provincial regions of Southwest China
    Bei Li, Xian-Guo Guo, Tian-Guang Ren, Pei-Ying Peng, Wen-Yu Song, Yan Lv, Peng-Wu Yin, Zhe Liu, Xin-Hang Liu, Ti-Jun Qian
    International Journal for Parasitology: Parasites and Wildlife.2022; 19: 169.     CrossRef
  • Preliminary Study on Species Diversity and Community Characteristics of Gamasid Mites on Small Mammals in Three Parallel Rivers Area of China
    Juan-Xiu Zhou, Xian-Guo Guo, Wen-Yu Song, Cheng-Fu Zhao, Zhi-Wei Zhang, Rong Fan, Ting Chen, Yan Lv, Peng-Wu Yin, Dao-Chao Jin
    Animals.2022; 12(22): 3217.     CrossRef
  • 5,604 View
  • 85 Download
  • 15 Web of Science
  • Crossref

Case Reports

Helminth Eggs Detected in Soil Samples of a Possible Toilet Structure Found at the Capital Area of Ancient Baekje Kingdom of Korea
Chang Seok Oh, Sang-Yuck Shim, Yongjun Kim, Jong Ha Hong, Jong-Yil Chai, Hisashi Fujita, Min Seo, Dong Hoon Shin
Korean J Parasito 2021;59(4):393-397.
Published online August 18, 2021
DOI: https://doi.org/10.3347/kjp.2021.59.4.393
Although research conducted in East Asia has uncovered parasite eggs from ancient toilets or cesspits, data accumulated to date needs to be supplemented by more archaeoparasitological studies. We examined a total of 21 soil samples from a toilet-like structure at the Hwajisan site, a Baekje-period royal villa, in present-day Korea. At least 4 species of helminth eggs, i.e., Trichuris trichiura, Ascaris lumbricoides, Clonorchis sinensis, and Trichuris sp. (or Trichuris vulpis) were detected in 3 sediment samples of the structure that was likely a toilet used by Baekje nobles. The eggs of T. trichiura were found in all 3 samples (no. 1, 4, and 5); and A. lumbricoides eggs were detected in 2 samples (no. 4 and 5). C. sinensis and T. vulpis-like eggs were found in no. 5 sample. From the findings of this study, we can suppose that the soil-transmitted helminths were prevalent in ancient Korean people, including the nobles of Baekje Kingdom during the 5th to 7th century.

Citations

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  • Clonorchis sinensis and Cholangiocarcinoma
    Eun-Min Kim, Sung-Tae Hong
    Journal of Korean Medical Science.2025;[Epub]     CrossRef
  • Problems in Japanese archaeoparasitology: Analysis of paleo-parasitic eggs from Hachinohe Castle
    Hisashi Fujita, Masako Funaba, Shiori O. Fujisawa
    Parasites, Hosts and Diseases.2025; 63(3): 278.     CrossRef
  • Paleoparasitology research on ancient helminth eggs and larvae in the Republic of Korea
    Jong-Yil Chai, Min Seo, Dong Hoon Shin
    Parasites, Hosts and Diseases.2023; 61(4): 345.     CrossRef
  • 4,329 View
  • 104 Download
  • 3 Web of Science
  • Crossref
COVID-19 and Plasmodium ovale Malaria: A Rare Case of Co-Infection
Bilge Caglar, Ridvan Karaali, Ilker Inanc Balkan, Bilgul Mete, Gokhan Aygun
Korean J Parasito 2021;59(4):399-402.
Published online August 18, 2021
DOI: https://doi.org/10.3347/kjp.2021.59.4.399
The COVID-19 pandemic continues to be a major health problem worldwide. Timely diagnosis of co-infections mimicking COVID-19, such as malaria, might be challenging particularly in non-endemic areas. We report the first case of COVID-19 and Plasmodium ovale malaria co-infection from our region aiming to highligt the importance of travel history and prophylaxis in malaria management in the context of pandemic. The galloping sound can sometimes be a harbinger of zebra besides the horse.

Citations

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  • Optimal control analysis of a mathematical model of malaria and COVID-19 co-infection dynamics
    Abou Bakari Diabaté, Boureima Sangaré, Ousmane Koutou
    Journal of Biological Dynamics.2025;[Epub]     CrossRef
  • Safety and Efficacy of Imatinib, Nilotinib, and Artesunate in COVID-19 Patients: A Systematic Review of Current Evidence
    Ehsan Ghavimehr, Ali Zand, Seyed Ahmad SeyedAlinaghi, Amirali Karimi, Hamid Zaferani Arani, Pegah Mirzapour, Zahra Pashaei, Esmaeil Mehraeen, Omid Dadras
    Anti-Infective Agents.2024;[Epub]     CrossRef
  • COVID-19 and malaria co-infection: a systematic review of clinical outcomes in endemic areas
    Amal H. Mohamed, Ebtihal Eltyeb, Badria Said, Raga Eltayeb, Abdullah Algaissi, Didier Hober, Abdulaziz H. Alhazmi
    PeerJ.2024; 12: e17160.     CrossRef
  • Effect of the second and third COVID-19 pandemic waves on routine outpatient malaria indicators and case management practices in Uganda: an interrupted time series analysis
    Pius Mukisa, Freddy Eric Kitutu, Arthur Mpimbaza, Jaffer Okiring, Joan N. Kalyango, Joaniter I. Nankabirwa
    Malaria Journal.2024;[Epub]     CrossRef
  • Mixed infection with COVID-19 and tropical malaria (case report)
    Dmitriy O. Efremov, Ainur R. Khuramshin, Sergey S. Кozlov, Nikolay I. Gulyaev
    Epidemiology and Infectious Diseases.2023; 28(1): 53.     CrossRef
  • Co-infection of COVID-19 and parasitic diseases: A systematic review
    Fatemeh Nemati Zargaran, Mosayeb Rostamian, Sara Kooti, Hamid Madanchi, Keyghobad Ghadiri
    Parasite Epidemiology and Control.2023; 21: e00299.     CrossRef
  • Clinical characteristics of malaria in COVID-19: A systematic review of case reports
    Chandana Rayella, Praveen Devanandan, Kavitha Rasuri, Sai Sudha Yerravelly, Sanjana Andem, Ranadheer Chowdary Puvvada
    Tropical Parasitology.2023; 13(1): 22.     CrossRef
  • MIS-C and co-infection with P. vivax and P. falciparum in a child: a clinical conundrum
    Michela Scalisi, Salvatore Giordano, Laura Antonella Canduscio, Maria Concetta Failla, Luca Messina, Elisa Sferrazza, Raffaella Rubino, Lucia Siracusa, Veronica Vanella, Antonio Cascio, Claudia Colomba
    Italian Journal of Pediatrics.2022;[Epub]     CrossRef
  • Co-Infection with Plasmodium vivax and COVID-19 in Thailand
    Parat Boonyarangka, Kittijarankon Phontham, Sabaithip Sriwichai, Kamonporn Poramathikul, Krit Harncharoenkul, Worachet Kuntawunginn, Napat Maneesrikhum, Sarayouth Srisawath, Chanida Seenuan, Chattakorn Thanyakait, Kanjana Inkabajan, Suda Pludpiem, Kingkan
    Tropical Medicine and Infectious Disease.2022; 7(8): 145.     CrossRef
  • SARS-CoV-2 and Plasmodium falciparum Co-Infection in a Returning Traveler
    Qian Huang, Wen-Jie Xu, Xiao-Xiao Wang, Xuan Zhang, Ke-Nu Pan, Jia-Qi Zhang, Hua-Liang Chen, Wei Ruan, Li-Nong Yao
    Frontiers in Public Health.2022;[Epub]     CrossRef
  • The striking mimics between COVID-19 and malaria: A review
    Emadeldin Hassan E. Konozy, Makarim El-fadil M. Osman, George Ghartey-Kwansah, Hind Mohamed Abushama
    Frontiers in Immunology.2022;[Epub]     CrossRef
  • 4,961 View
  • 136 Download
  • 9 Web of Science
  • Crossref

Brief Communications

Anticoccidial Activity of Berberine against Eimeria-Infected Chickens
Binh Thanh Nguyen, Rochelle Alipio Flores, Paula Leona Taymen Cammayo, Suk Kim, Woo Hyun Kim, Wongi Min
Korean J Parasito 2021;59(4):403-408.
Published online August 18, 2021
DOI: https://doi.org/10.3347/kjp.2021.59.4.403
Avian coccidiosis has a major economic impact on the poultry industry, it is caused by 7 species of Eimeria, and has been primarily controlled using chemotherapeutic agents. Due to the emergence of drug-resistant strains, alternative control strategies are needed. We assessed anticoccidial effects of berberine-based diets in broiler chickens following oral infection with 5 Eimeria species (E. acervulina, E. maxima, E. tenella, E. mitis, and E. praecox). When 0.2% berberine, a concentration that does not affect weight gain, was added to the diet, the 4 groups infected with E. acervulina, E. tenella, E. mitis, or E. praecox showed significant reductions in fecal oocyst shedding (P<0.05) compared to their respective infected and untreated controls. In chickens treated 0.5% berberine instead of 0.2% and infected with E. maxima, fecal oocyst production was significantly reduced, but body weight deceased, indicating that berberine treatment was not useful for E. maxima infection. Taken together, these results illustrate the applicability of berberine for prophylactic use to control most Eimeria infections except E. maxima. Further studies on the mechanisms underlying the differences in anticoccidial susceptibility to berberine, particularly E. maxima, are remained.

Citations

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  • Evaluation of the Effectiveness of a Phytogenic Supplement (Alkaloids and Flavonoids) in the Control of Eimeria spp. in Experimentally Challenged Broiler Chickens
    Anne-Sophie Hascoët, Paulina Torres-Celpa, Roberto Riquelme-Neira, Héctor Hidalgo-Olate
    Animals.2025; 15(6): 847.     CrossRef
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Molecular Identification of Cryptosporidium viatorum Infection in a Patient Suffering from Unusual Cryptosporidiosis in West Bengal, India
Sanjib Kumar Sardar, Ajanta Ghosal, Yumiko Saito-Nakano, Shanta Dutta, Tomoyoshi Nozaki, Sandipan Ganguly
Korean J Parasito 2021;59(4):409-413.
Published online August 18, 2021
DOI: https://doi.org/10.3347/kjp.2021.59.4.409
In this study, we have collected and screened a total of 268 stool samples from diarrheal patients admitted to an Infectious disease hospital in Kolkata for the presence of Cryptosporidium spp. The initial diagnosis was carried out by microscopy followed by genus specific polymerase chain reaction assays based on 70 kDa heat shock proteins (HSP70). DNA sequencing of the amplified locus has been employed for determination of genetic diversity of the local isolates. Out of 268 collected samples, 12 (4.48%) were positive for Cryptosporidium spp. Sequences analysis of 70 kDa heat shock proteins locus in 12 Cryptosporidium local isolates revealed that 2.24% and 1.86% of samples were showing 99% to 100% identity with C. parvum and C. hominis. Along with the other 2 major species one recently described globally distributed pathogenic species Cryptosporidium viatorum has been identified. The HSP70 locus sequence of the isolate showed 100% similarity with a previously described isolate of C. viatorum (Accession No. JX978274.1, JX978273.1, and JN846706.1) present in GenBank.

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  • 5 Web of Science
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Seroprevalence of Plasmodium vivax Circumsporozoite Protein Antibody in High-Risk Malaria Areas in Korea
Jinyoung Lee, Kyoung Jin, Seong Kyu Ahn, Sung-Keun Lee, Hyung Wook Kwon, Byoung-Kuk Na, Tong-Soo Kim
Korean J Parasito 2021;59(4):415-419.
Published online August 18, 2021
DOI: https://doi.org/10.3347/kjp.2021.59.4.415
The circumsporozoite protein (CSP) of Plasmodium spp. is a diagnostic antigen and useful biomarker for monitoring short-term/seasonal changes to malaria transmission. Using P. vivax CSP antibody ELISA, epidemiological characteristics were analyzed in the residents of Ganghwa, Cheorwon, Paju, and Goseong from 2017 to 2018. In Ganghwa and Cheorwon, 1.6% and 1.2% of residents, respectively, were PvCSP-antibody-positive in 2018, which indicates a decrease of 0.4% in the positive rate compared to 2017. The annual parasite incidence (API) in Ganghwa and Cheorwon was 24.9 and 10.5 in 2017 and 20.3 and 10.7 in 2018, respectively. Although the changes were not significant, the API in Ganghwa decreased slightly by 4.5 in 2018 compared to the previous year. In Paju and Goseong, 3.9% and 2.0% of residents were positive for the PvCSP antibody. The API in Paju was 13.1 in 2017 and 16.0 in 2018, although no malaria patients were reported for the 2 years. Therefore, the results suggest that PvCSP is a useful antigen for confirming initial malaria infection. Additionally, considering that the antibody is relatively transient, it can be employed for sero-epidemiological studies to determine the extent of malaria transmission in the current year.

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    European Journal of Medical Research.2021;[Epub]     CrossRef
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  • 3 Web of Science
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Enterobius vermicularis Infection among Preschool Children: A 12-Year (2008-2019) Survey in Large Cities and Provinces of the Republic of Korea
Hyejoo Shin, Bong-Kwang Jung, Seungwan Ryoo, Sooji Hong, Taehee Chang, Jiyeon Park, Keon Hoon Lee, Jeonggyu Lee, Jae Young Park, Hoo-Gn Jeoung, Jae Hyun Cho, Jong-Yil Chai
Korean J Parasito 2021;59(4):421-426.
Published online August 18, 2021
DOI: https://doi.org/10.3347/kjp.2021.59.4.421
A 12-year nationwide survey (2008-2019) was performed to investigate the prevalence of Enterobius vermicularis infection among preschool children in Seoul, 4 large cites (Busan, Incheon, Daegu, and Ulsan), and 9 provinces (grouped into 5 localities) in the Republic of Korea (=Korea). The survey was carried out once a year by 16 regional offices of the Korea Association of Health Promotion. The cello-tape perianal swab method (1 smear per child) was applied to detect eggs of E. vermicularis and other helminths. According to the results, the egg positive rate of E. vermicularis infection in 2008-2009 was 1.8-2.0%, but it decreased gradually to 0.6% in 2019 (P<0.05). The prevalence was significantly higher in boys (0.7-5.0%, mean 1.8%) than in girls (0.5-2.8%, mean 1.3%) (P<0.05). The 2 most southern localities, Jejudo (Province) and Jeolla-do (inclusive of Jeollabuk-do and Jeollanam-do) and a mid-western province, Gyeonggi-do, revealed higher prevalences, whereas Seoul and Gangwon-do showed lower prevalences. The results indicate that a low-grade prevalence of E. vermicularis infection (less than 4%) has been maintained for the recent 12 years among preschool children in Korea. Continuous monitoring of enterobiasis in the child age group is necessary in Korea.

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  • Positive rates for Enterobius vermicularis eggs among preschool children in Yeosu-si, Jeollanam-do, Korea (2017-2021)
    Myoung-Ro Lee, Hee-Eun Shin, Seon-Ok Back, Young-Ju Lee, Jung-Won Ju, Chun Soon Park, Hee-Il Lee
    Parasites, Hosts and Diseases.2023; 61(1): 84.     CrossRef
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Survey of Zoonotic Trematode Metacercariae in Fish from Irrigation Canal of Togyo-jeosuji (Reservoir) in Cheorwon-gun, Gangwon-do, Republic of Korea
Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Hee Il Lee, Jung-Won Ju, Myoung-Ro Lee, Eun-Joo Lim, Sung Yong Son, Eunmi Ko, Jaeseok Choi
Korean J Parasito 2021;59(4):427-432.
Published online August 18, 2021
DOI: https://doi.org/10.3347/kjp.2021.59.4.427
The infection status of zoonotic trematode metacercariae (ZTM) was investigated in total 568 freshwater fishes (19 species) from the irrigation canal of Togyo-jeosuji (Reservoir) in Cheorwon-gun, Gangwon-do, the Republic of Korea for 3 years (2018-2020). All fishes were examined using the artificial digestion method. The metacercariae of Clonorchis sinensis (CsMc) were detected in 180 (43.8%) out of 411 fish of positive species, and their infection intensity was 38 per fish infected (PFI). Especially, in 2 fish species, i.e., Pseudorasbora parva and Puntungia herzi, the prevalence was 82.1% and 31.3%, and the infection intensity with CsMc was 88 and 290 PFI, respectively. Metagonimus spp. metacercariae (MsMc) were found in 403 (74.1%) out of 544 fish of positive species, and their infection intensity was 62 PFI. In the pale chub, Zacco platypus, the prevalence of MsMc was 98.6%, and their infection intensity was 144 PFI. Centrocestus armatus metacercariae were detected in 171 (38.9%) out of 440 fish of positive species, and their infection intensity was 1,844 PFI. Echinostoma spp. metacercariae were found in 94 (19.6%) out of 479 fish of positive species, and their infection intensity was 3 PFI. Metorchis orientalis metacercariae were detected in 43 (29.3%) out of 147 fish of positive species, and their infection intensity was 4 PFI. By the present study, it has been confirmed that some species of ZTM, including CsMc and MsMc, are prevalent in fishes from the irrigation canal of Togyo-jeosuji in Cheorwon-gun, Gangwon-do, Korea.

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    Parasitology.2022; 149(10): 1296.     CrossRef
  • Integrative Transcriptomics and Proteomics Analyses to Reveal the Developmental Regulation of Metorchis orientalis: A Neglected Trematode With Potential Carcinogenic Implications
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    Frontiers in Cellular and Infection Microbiology.2021;[Epub]     CrossRef
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  • 78 Download
  • 6 Web of Science
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