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Phylogenetic Characteristics of Echinococcus granulosus Sensu Lato in Uzbekistan
Hye-Jin Kim, Tai-Soon Yong, Myeong Heon Shin, Kyu-Jae Lee, Gab-Man Park, Uktamjon Suvonkulov, Dmitriy Kovalenko, Hak Sun Yu
Korean J Parasitol 2020;58(2):205-210.
Published online April 30, 2020
DOI: https://doi.org/10.3347/kjp.2020.58.2.205
Echinococcosis occurs mainly in areas with heavy livestock farming, such as Central Asia, America, and Australia. Echinococcus granulosus sensu lato (s.l.) infection causes echinococcosis in intermediate hosts, such as sheep, cattle, goats, camels, and horses. Numerous cases of echinococcosis occur in Uzbekistan as stock farming is a primary industry. Epidemiological and genetic studies of E. granulosus s.l. are very important for mitigating its impact on public health and the economy; however, there are no such studies on E. granulosus s.l. in Uzbekistan. In the present study, to determine which genotypes exist and are transmitted, we isolated Echinococcus sp. from definitive hosts (one isolate each from jackal and dog) and intermediate hosts (52 isolates from humans and 6 isolates from sheep) in Uzbekistan and analyzed the isolates by sequencing 2 mitochondrial DNA components (cox1 and nad1). The results showed that all of isolates except one belonged to the E. granulosus sensu stricto (s.s.) G1 and G3 genotypes. Phylogenetic analysis based on cox1 sequences showed that 42 isolates from humans, 6 isolates from sheep, and one isolate from jackal were the G1 genotype, whereas the remaining 8 isolates from human and the one isolate from dog were the G3 genotype. These results suggest that the G1 and G3 genotypes of E. granulosus s.s. are predominant in Uzbekistan, and both wild animals and domestic animals are important for maintaining their life cycle. Only one isolate from human sample was confirmed to be E. eqiinus (G4 genotype), which is known to be for the first time.

Citations

Citations to this article as recorded by  Crossref logo
  • Cystic echinococcosis due to Echinococcus equinus in a Swiss donkey
    Isabelle L. Piotrowski, Rosalie Fabian, Stefanie M. Ohlerth, Felix Grimm, Meret E. Wehrli Eser
    Equine Veterinary Education.2025;[Epub]     CrossRef
  • Morphological and molecular investigation of hydatid cyst isolated from small ruminants in Rasht, Iran
    Saeed Farokhpey, Soheil Sadr, Saeed Yaghfoori, Hassan Borji
    Journal of Parasitic Diseases.2025; 49(4): 944.     CrossRef
  • Echinococcus species in wildlife
    Thomas Romig, Marion Wassermann
    International Journal for Parasitology: Parasites and Wildlife.2024; 23: 100913.     CrossRef
  • Evaluation of the Molecular Properties of Echinococcus granulosus Isolates from Various Hosts in Şanlıurfa Province
    Cemile Günbegi Çalışkan, Fadile Yıldız Zeyrek
    Journal of Anatolian Environmental and Animal Sciences.2024; 9(3): 383.     CrossRef
  • Cystic echinococcosis in donkeys in eastern Africa
    Erastus Mulinge, Eberhard Zeyhle, Cecilia Mbae, Lucy Gitau, Timothy Kaburu, Japhet Magambo, Ute Mackenstedt, Thomas Romig, Peter Kern, Marion Wassermann
    Parasitology.2023; 150(5): 468.     CrossRef
  • Genotyping of Echinococcus granulosus isolated from canine in Northwest Iran
    Zabih Zarei, Behnam Mohammadi Ghalehbin, Behnaz Akhoundi, Mehdi Mohebali, Zahra Heidari
    Journal of Parasitic Diseases.2023; 47(4): 757.     CrossRef
  • Genetic diversity of Echinococcus granulosus sensu lato in China: Epidemiological studies and systematic review
    Rui‐Qi Hua, Xiao‐Di Du, Xue He, Xiao‐Bin Gu, Yue Xie, Ran He, Jing Xu, Xue‐Rong Peng, Guang‐You Yang
    Transboundary and Emerging Diseases.2022;[Epub]     CrossRef
  • Species and genotypes belonging to Echinococcus granulosus sensu lato complex causing human cystic echinococcosis in Europe (2000–2021): a systematic review
    Adriano Casulli, Alessandro Massolo, Urmas Saarma, Gérald Umhang, Federica Santolamazza, Azzurra Santoro
    Parasites & Vectors.2022;[Epub]     CrossRef
  • Insights into Human Cystic Echinococcosis in the Kurdistan Region, Iraq: Characteristics and Molecular Identification of Cysts
    Araz Ramadhan Issa, Sardar Hassan Arif, Ayad Ahmad Mohammed, Federica Santolamazza, Azzurra Santoro, Wijdan Mohammed Salih Mero, Adriano Casulli
    Pathogens.2022; 11(4): 408.     CrossRef
  • Global distribution of Echinococcus granulosus genotypes in domestic and wild canids: a systematic review and meta-analysis
    Morteza Shams, Sasan Khazaei, Razi Naserifar, Seyyed Ali Shariatzadeh, Davood Anvari, Fattaneh Montazeri, Majid Pirestani, Hamidreza Majidiani
    Parasitology.2022; 149(9): 1147.     CrossRef
  • Food-borne zoonotic echinococcosis: A review with special focus on epidemiology
    Mughees Aizaz Alvi, Abdullah F. Alsayeqh
    Frontiers in Veterinary Science.2022;[Epub]     CrossRef
  • Molecular Epidemiology of Cystic Echinococcosis in Rural Baluchistan, Pakistan: A Cross-Sectional Study
    Ihsan Ullah, Sadia Sattar, Ijaz Ali, Arshad Farid, Amin Ullah, Refaat A. Eid, Mohamed Samir A. Zaki, Muhammad Alaa Eldeen, Iftikhar Ahmed, Irfan Ullah
    Pathogens.2022; 12(1): 40.     CrossRef
  • Relevance of Human Leukocyte Antigen (HLA) class ll alleles in susceptibility or resistance to Echinococcus granulosus infection. Systematic review
    Facundo Martín Cardozo, Andrea Florencia Maglioco
    Data and Metadata.2022; 1: 37.     CrossRef
  • A case of human cystic echinococcosis acquired in Ireland
    Caroline Conlon, Conor Grant, Helen Tuite, Catherine Fleming, Eoin Slattery
    Parasitology International.2021; 81: 102249.     CrossRef
  • Occurrence of Echinococcusgranulosussensulato and Other Taeniids in Bhutan
    Puspa M. Sharma, Nirmal K. Thapa, Pema Tshomo, Tshewang Dema, Cristian A. Alvarez Rojas, Tenzin Tenzin, Ratna B. Gurung, Tshering Norbu, Lhatru Lhatru, Phurpa Namgyel, Chimi Jamtsho, Kinzang Dukpa, Yoenten Phuentshok, Krishna P. Sharma, Sonam Pelden, Pete
    Pathogens.2021; 10(3): 330.     CrossRef
  • Cystic echinococcosis in sheep and goats of Lebanon
    Gaelle Joanny, Naunain Mehmood, Giorgia Dessì, Claudia Tamponi, Francesca Nonnis, Chadi Hosri, Urmas Saarma, Antonio Varcasia, Antonio Scala
    Parasitology.2021; 148(7): 871.     CrossRef
  • Pulmonary hydatidosis genotypes isolates from human clinical surgery based on sequencing of mitochondrial genes in Fars, Iran
    Parviz Mardani, Ali Talebi Ezabadi, Bahareh Sedaghat, Seyed Mahmoud Sadjjadi
    Journal of Cardiothoracic Surgery.2021;[Epub]     CrossRef
  • An annotated checklist of the eukaryotic parasites of humans, exclusive of fungi and algae
    Blaine A. Mathison, Sarah G. H. Sapp
    ZooKeys.2021; 1069: 1.     CrossRef
  • A validated method to identify Echinococcus granulosus sensu lato at species level
    F. Santolamazza, A. Santoro, A. Possenti, S.M. Cacciò, A. Casulli
    Infection, Genetics and Evolution.2020; 85: 104575.     CrossRef
  • 7,719 View
  • 161 Download
  • 19 Web of Science
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Prevalence of Intestinal Helminth Infections in Dogs and Two Species of Wild Animals from Samarkand Region of Uzbekistan
Tai-Soon Yong, Kyu-Jae Lee, Myeong Heon Shin, Hak Sun Yu, Uktamjon Suvonkulov, Turycin Bladimir Sergeevich, Azamat Shamsiev, Gab-Man Park
Korean J Parasitol 2019;57(5):549-552.
Published online October 31, 2019
DOI: https://doi.org/10.3347/kjp.2019.57.5.549
This study aimed to determine the prevalence of intestinal helminth parasitic infections and associated risk factors for the human infection among the people of Samarkand, Uzbekistan. Infection status of helminths including Echinococcus granulosus was surveyed in domestic and wild animals from 4 sites in the Samarkand region, Uzbekistan during 2015-2018. Fecal samples of each animal were examined with the formalin-ether sedimentation technique and the recovery of intestinal helminths was performed with naked eyes and a stereomicroscope in total 1,761 animals (1,755 dogs, 1 golden jackal, and 5 Corsac foxes). Total 658 adult worms of E. granulosus were detected in 28 (1.6%) dogs and 1 (100%) golden jackal. More than 6 species of helminths, i.e., Taenia hydatigena, Dipylidium caninum, Diplopylidium nolleri, Mesocestoides lineatus, Toxocara canis, and Trichuris vulpis, were found from 18 (1.0%) dogs. Six (T. hydatigena, Toxascaris leonina, Alaria alata, Uncinaria stenocephala, D. caninum, and M. lineatus) and 2 (D. nolleri and M. lineatus) species of helminths were also detected from 5 Corsac foxes and 1 golden jackal, respectively. Taeniid eggs were found in 2 (20%) out of 10 soil samples. In the present study, it was confirmed that the prevalences of helminths including E. granulosus are not so high in domestic and wild animals. Nevertheless, the awareness on the zoonotic helminth infections should be continuously maintained in Uzbekistan for the prevention of human infection.

Citations

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  • Molecular identification and phylogenetic positioning of nematodes Toxocara canis, T. cati (Ascarididae) and Toxascaris leonina (Toxocaridae) from domestic and wild carnivores in the Fergana Valley, Uzbekistan
    A. E. Kuchboev, A. G. Sotiboldiyev, B. K. Ruziev, A. A. Safarov
    Biosystems Diversity.2025; 33(3): e2538.     CrossRef
  • High-Quality Chromosome-Level Genome Assembly of the Corsac Fox (Vulpes corsac) Reveals Adaptation to Semiarid and Harsh Environments
    Zhihao Zhang, Tian Xia, Shengyang Zhou, Xiufeng Yang, Tianshu Lyu, Lidong Wang, Jiaohui Fang, Qi Wang, Huashan Dou, Honghai Zhang
    International Journal of Molecular Sciences.2023; 24(11): 9599.     CrossRef
  • Time series modeling of animal bites
    Fatemeh Rostampour, Sima Masoudi
    Journal of Acute Disease.2023; 12(3): 121.     CrossRef
  • Diagnostic tools for the detection of taeniid eggs in different environmental matrices: A systematic review.
    Ganna Saelens, Lucy Robertson, Sarah Gabriël
    Food and Waterborne Parasitology.2022; 26: e00145.     CrossRef
  • Fleas from the Silk Road in Central Asia: identification of Ctenocephalides canis and Ctenocephalides orientis on owned dogs in Uzbekistan using molecular identification and geometric morphometrics
    Georgiana Deak, Alisher Safarov, Xi Carria Xie, Runting Wang, Andrei Daniel Mihalca, Jan Šlapeta
    Parasites & Vectors.2022;[Epub]     CrossRef
  • Control of cystic echinococcosis in the Middle Atlas, Morocco: Field evaluation of the EG95 vaccine in sheep and cesticide treatment in dogs
    Fatimaezzahra Amarir, Abdelkbir Rhalem, Abderrahim Sadak, Marianne Raes, Mohamed Oukessou, Aouatif Saadi, Mohammed Bouslikhane, Charles G. Gauci, Marshall W. Lightowlers, Nathalie Kirschvink, Tanguy Marcotty, María-Gloria Basáñez
    PLOS Neglected Tropical Diseases.2021; 15(3): e0009253.     CrossRef
  • Co-infection of Trichuris vulpis and Toxocara canis in different aged dogs: Influence on the haematological indices
    I. V. Saichenko, A. A. Antipov, T. I. Bakhur, L. V. Bezditko, S. S. Shmayun
    Biosystems Diversity.2021; 29(2): 129.     CrossRef
  • Spread and seasonal dynamics of dogs helminthiasis in BilaTserkva district
    I. Saichenko
    Naukovij vìsnik veterinarnoï medicini.2021; (1(165)): 119.     CrossRef
  • Monitoring of parasitic diseases of dogs
    Bogdan Morozov, Andrii Berezovskyi
    EUREKA: Health Sciences.2021; (4): 109.     CrossRef
  • An epizootic situation is in relation to the nematodosiss of gastroenteric channel of dogs
    I. Saichenko, A. Antipov
    Naukovij vìsnik veterinarnoï medicini.2020; (1(154)): 54.     CrossRef
  • 7,165 View
  • 140 Download
  • 8 Web of Science
  • Crossref
Practical Algorisms for PCR-RFLP-Based Genotyping of Echinococcus granulosus Sensu Lato
Hye-Jin Kim, Tae-Soon Yong, Myeong Heon Shin, Kyu-Jae Lee, Gab-Man Park, Uktamjon Suvonkulov, Dmitriy Kovalenko, Hak Sun Yu
Korean J Parasitol 2017;55(6):679-684.
Published online December 31, 2017
DOI: https://doi.org/10.3347/kjp.2017.55.6.679
Echinococcus granulosus sensu lato (s.l.) is a causative agent of cystic echinococcosis or cystic hydatid disease in humans and domestic and wild animals. The disease is a serious health problem in countries associated with poverty and poor hygiene practices, particularly in livestock raising. We introduced a practical algorism for genotyping the parasite, which may be useful to many developing countries. To evaluate the efficiency of the algorism, we genotyped 3 unknown strains isolated from human patients. We found that unknowns 1 and 3 were included in G1, G2, and G3 genotypes group and unknown 2 was included in G4 genotype (Echinococcus equinus) according to the algorisms. We confirmed these results by sequencing the 3 unknown isolates cox1 and nad1 PCR products. In conclusion, these new algorisms are very fast genotype identification tools that are suitable for evaluating E. granulosus s.l. isolated from livestock or livestock holders, particularly in developing countries.

Citations

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  • Primary cerebral cystic echinococcosis in a child from Roman countryside: Source attribution and scoping review of cases from the literature
    Adriano Casulli, Stefania Pane, Franco Randi, Paola Scaramozzino, Andrea Carvelli, Carlo Efisio Marras, Andrea Carai, Azzurra Santoro, Federica Santolamazza, Francesca Tamarozzi, Lorenza Putignani, Solange Bresson-Hadni
    PLOS Neglected Tropical Diseases.2023; 17(9): e0011612.     CrossRef
  • A validated method to identify Echinococcus granulosus sensu lato at species level
    F. Santolamazza, A. Santoro, A. Possenti, S.M. Cacciò, A. Casulli
    Infection, Genetics and Evolution.2020; 85: 104575.     CrossRef
  • A pilot comparative study between serological and genetic investigations in relationship to clinical outcomes on patients with cystic echinococcosis
    Nu. Altintas, S. A. Karamil, O. Turkum, M. Akil, A. Sakarya, H. Bozkaya, J. Šoltys, Na. Altintas
    Helminthologia.2020; 57(2): 91.     CrossRef
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    Cancer Reports.2019;[Epub]     CrossRef
  • 8,580 View
  • 182 Download
  • 6 Web of Science
  • Crossref
Status of intestinal parasite infections among children in Bat Dambang, Cambodia
Seung Kyu Park, Dong-Heui Kim, Young-Kun Deung, Hun-Joo Kim, Eun-Ju Yang, Soo-Jung Lim, Yong-Suk Ryang, Dan Jin, Kyu-Jae Lee
Korean J Parasitol 2004;42(4):201-203.
Published online December 20, 2004
DOI: https://doi.org/10.3347/kjp.2004.42.4.201

A survey was conducted to determine the extent of intestinal parasite infection in Bat Dambang, Cambodia in March 2004. A total of 623 fecal specimens was collected from kindergarten and schoolchildren and examined using the formalin-ether sedimentation technique. The overall infection rate of intestinal parasites was 25.7% (boys, 26.2%; girls, 25.1%), and the infection rates of intestinal helminthes by species were as follows: Echinostoma sp. 4.8%, hookworm 3.4%, Hymenolepis nana 1.3%, and Rhabditis sp. 1.3%. The infection rates of intestinal protozoa were; Entamoeba coli 4.8%, Giardia lamblia 2.9%, Iodamoeba butschlii 1.4%, Entamoeba polecki 1.1%, and Entamoeba histolytica 0.8%. There were no egg positive cases of Ascaris lumbricoides or Trichuris trichiura. All children infected were treated with albendazole, praziquantel, or metronidazole according to parasite species. The results showed that intestinal parasites are highly endemic in Bat Dambang, Cambodia.

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    Chien-Wei Liao, Ting-Wu Chuang, Ying-Chieh Huang, Chia-Mei Chou, Chia-Lien Chiang, Fei-Peng Lee, Yun-Ting Hsu, Jia-Wei Lin, Kennar Briand, Chia-Ying Tu, Chia-Kwung Fan
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Original Article

Susceptibility of several strains of mice to Echinostoma hortense infection
Kyu-Jae Lee, Seung Kyu Park, Jee Aee Im, Soo Kie Kim, Geun Ha Kim, Gwang Young Kim, Eun Ju Yang, Yong-Suk Ryang
Korean J Parasitol 2004;42(2):51-56.
Published online June 20, 2004
DOI: https://doi.org/10.3347/kjp.2004.42.2.51

Susceptibilities of 5 different mice strains, including C3H/HeN, BALB/c, C57BL6, FvB and ICR, to Echinostoma hortense infection, was evaluated. The worm expulsion rate, worm size and egg production were observed from 1 to 8 weeks after infection with 30 metacercariae. C3H/HeN and ICR mice showed the highest worm maturation rates. The worm recovery rate and the number of eggs per gram (EPG) of feces was also higher in C3H/HeN and ICR mice than in BALB/c, C57BL6, and FvB mice. It is suggested that E. hortense is highly infectious to ICR and C3H/HeN mice, but not to the other strains of mice. Based on the results obtained, we believe that the susceptibility of different mouse strains to E. hortense infection is dependent on the genetic and immunologic background of mice.

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Brief Communication

The intestinal parasite infection status of inhabitants in the Roxas city, the Philippines
Bong-Jin Kim, Mee-Sun Ock, Dong-Il Chung, Tai-Soon Yong, Kyu-Jae Lee
Korean J Parasitol 2003;41(2):113-115.
Published online June 20, 2003
DOI: https://doi.org/10.3347/kjp.2003.41.2.113

We carried out a small-scale survey to investigate the status of intestinal protozoa and helminthes infection of inhabitants in Roxas city, Mindoro, the Philippines. Total 301 stool samples were subjected to the formalin-ether concentration method for the detection of helminth ova and protozoan cysts. The overall positive rate was 64.5%, and that of male and female were 56.6% and 72.5%, respectively. The highest infected helminth was Ascaris lumbricoudes (51.2%), followed by Trichuris trichiura (27.6%), hookworm (8.0%) and Enterobius vermicularis (0.3%). The protozoa infection status revealed that Entamoeba coli was the most frequent (15.0%). Iodoamoeba buetschlii and E. histolytica were found but few. The multiple infection more than two parasites was 29.6%, and double infection with A. lumbricoides and T. trichiura was most common. The intestinal helminth infections were highly prevalent in this area, according to this result, and we concluded that anthelminthic drugs should be given to inhabitants, especially to children of 1 to 15 years-old.

Citations

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Original Articles

A survey on head lice infestation in Korea (2001) and the therapeutic efficacy of oral trimethoprim/sulfamethoxazole adding to lindane shampoo
Seobo Sim, In-Yong Lee, Kyu-Jae Lee, Jang-Hoon Seo, Kyung-Il Im, Myeong Heon Shin, Tai-Soon Yong
Korean J Parasitol 2003;41(1):57-61.
Published online March 20, 2003
DOI: https://doi.org/10.3347/kjp.2003.41.1.57

Total of 7,495 children including 3,908 boys and 3,587 girls from a kindergarten and 15 primary schools were examined for head lice infestation (HLI). The overall prevalence of HLI in this study was found to be 5.8%. Head lice were much more commonly detected in girls than in boys with prevalence of 11.2% and 0.9%, respectively. Sixty-nine children with HLI were treated with 1% lindane shampoo alone (group 1), and 45 children with HLI were treated with 1% lindane shampoo and oral trimethoprim/sulfamethoxazole (group 2), and follow-up visits were conducted 2 and 4 weeks later. The children who still had HLI 2 weeks after the primary treatment were treated again. At the 2-week follow-up visit, the treatment success rates of groups 1 and 2 were 76.8% and 86.7%, respectively, and at the 4-week follow-up visit, the rates were 91.3% and 97.8%, respectively. No statistically significant synergistic effect was observed for the combination of a 1% lindane shampoo and oral trimethoprim/sulfamethoxazole.

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A seroepidemiologic survey for human sparganosis in Gangweon-do
Kyu-Jae Lee, Yong-Tae Bae, Dong-Heui Kim, Young-Kun Deung, Yong-Suk Ryang
Korean J Parasitol 2002;40(4):177-180.
Published online December 30, 2002
DOI: https://doi.org/10.3347/kjp.2002.40.4.177

Gangweon-do is known to be highly endemic area of sparganosis more than other provinces in Korea. A seroepidmiologic examination for the detection of anti-Spirometra erinacei plerocercoid IgG in serum was carried out in normal inhabitants in Hongcheon-gun, Gangweon-do. Sere were tested by enzyme-linked immunosrobent assay (ELISA) for the anti-sparganum antibodies. Positive rate for anti-sparganum antibody in 719 adults was 3.3%. Data of the questionnaire for 24 ELISA positive inhabitants revealed that 20 had a history of eating raw meat of snakes, 24 had a history of eating frogs, and 24 had a history of drinking stream water. Two positive cases had a past history of sparganosis. Two positive cases showed current symptoms of sparganosis. The data revealed that ELISA would be useful to find infected cases among normal inhabitants at sparganosis-endemic areas.

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Brief Communications

Status of intestinal parasites infection among primary school children in Kampongcham, Cambodia
Kyu-Jae Lee, Yong-Tae Bae, Dong-Heui Kim, Young-Kun Deung, Yong-Suk Ryang, Hun-Joo Kim, Kyung-Il Im, Tai-Soon Yong
Korean J Parasitol 2002;40(3):153-155.
Published online September 30, 2002
DOI: https://doi.org/10.3347/kjp.2002.40.3.153

A survey was made to find the extent of intestinal parasite infection in Kampongcham, Cambodia in February 2002. A total of 251 fecal specimens were collected from Tonlebat primary school children and examined by formalin-ether sedimentation technique. The overall infection rate of intestinal parasite was 54.2% (males, 57.3%; females, 50.8%). The infection rate of intestinal helminths by the species were as follows: Ascaris lumbricoides 26.3%, Echinostoma sp. 15.6%, hookworm 6.4%, Opisthorchis sp. 4.0%, Rhabditis sp. 2.4%, and Trichuris trichiura 0.4%. The infection rate of intestinal protozoa were as follows: E. coli 7.6%, G. lamblia 3.2%, I. butschlii 3.2%, and E. histolytica 0.8%. More than two different kinds of parasites were found in 16.7% of the stool samples. All the children infected were treated with albendazole, praziquantel and metronidazole according to parasite species. The results showed that intestinal parasites are highly endemic in this area.

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Enterobius vermicularis egg positive rates in primary school children in Gangwon-do (Province), Korea
Kyu-Jae Lee, Yung-Kyum Ahn, Yong-Suk Ryang
Korean J Parasitol 2001;39(4):327-328.
Published online December 31, 2001
DOI: https://doi.org/10.3347/kjp.2001.39.4.327

A survey of the infection rate of Enterobius vermicularis among students in 4 primary schools located in Gangwon-do (Province) was done from May to June 2001. Among the 398 examinees, 39 (9.8%) were infected with E. vermicularis demonstrated by the adhesive cellotape anal swab method. The infection rates ranged from 8.3% to 11.8% among the four schools. The infection rate of males and females was 10.7% and 7,7% respectively. The first grade students showed the highest infection rate, 28.7%. The confirmed cases were treated with albendazole three times at an interval of 15 days. We were able to confirm that E. vermicularis infection is still prevalent among students in Gangwon-do, Korea.

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  • Enterobius vermicularis Infection among Preschool Children: A 12-Year (2008-2019) Survey in Large Cities and Provinces of the Republic of Korea
    Hyejoo Shin, Bong-Kwang Jung, Seungwan Ryoo, Sooji Hong, Taehee Chang, Jiyeon Park, Keon Hoon Lee, Jeonggyu Lee, Jae Young Park, Hoo-Gn Jeoung, Jae Hyun Cho, Jong-Yil Chai
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    Dong-Hee Kim, Hak Sun Yu, David Joseph Diemert
    PLoS ONE.2014; 9(11): e112149.     CrossRef
  • Comparison of Egg Positive Rates ofEnterobius vermicularisamong Preschool Children in Three Korean Localities
    Sung-Hee Hong, Sang-Eun Lee, Young-Il Jeong, Won-Ja Lee, Shin-Hyeong Cho
    The Korean Journal of Parasitology.2011; 49(4): 441.     CrossRef
  • Egg positive rate of Enterobius vermicularis among preschool children in Cheongju, Chungcheongbuk-do, Korea
    Seokha Kang, Hyeong Kyu Jeon, Keeseon S. Eom, Joong-Ki Park
    The Korean Journal of Parasitology.2006; 44(3): 247.     CrossRef
  • A survey of Enterobius vermicularis infection among children on western and southern coastal islands of the Republic of Korea
    Jae-Hwan Park, Eun-Taek Han, Won-Hee Kim, Eun-Hee Shin, Sang-Mee Guk, Jae-Lip Kim, Jong-Yil Chai
    The Korean Journal of Parasitology.2005; 43(4): 129.     CrossRef
  • Enterobius vermicularisinfection among population of General Mansilla, Argentina
    Betina C Pezzani
    World Journal of Gastroenterology.2004; 10(17): 2535.     CrossRef
  • Egg positive rate of Enterobius vermicularis of primary school children in Geoje island
    Bong Jin Kim, Bo Young Lee, Hyun Kee Chung, Young Sun Lee, Kun Hee Lee, Hae Jin Chung, Mee Sun Ock
    The Korean Journal of Parasitology.2003; 41(1): 75.     CrossRef
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    John Horton
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Original Article

Analysis of vivax malaria cases in Gangwon-do (Province), Korea in the year 2000
Kyu-Jae Lee, Chun-Bae Kim, Byong-Ju Choi, Kee-Ho Park, Jong-Ku Park
Korean J Parasitol 2001;39(4):301-306.
Published online December 31, 2001
DOI: https://doi.org/10.3347/kjp.2001.39.4.301

A total of 827 malaria cases were reported in the Gangwon-do in the year 2000. There were 18.2 cases per 100,000 inhabitants. There were 283 cases among civilians and 544 cases among the military. 90.6% of cases were reported in Cheorwon- (531), Hwacheon- (152), and Goseong- (66) gun (county), which bordered the demilitarized zone (DMZ). A distinct feature pertaining to the malaria cases in Gangwon-do is that the number of cases has increased about two times over the last year. The mean time from the beginning of symptoms to malaria diagnosis was five days. Control systems for malaria by public health organizations and military organizations are well maintained, but were not able to reduce the malaria prevalence rate. The cause for the increase in pattern of the malaria cases in Gangwon-do may be caused by the spreading of prevalent areas of malaria to the east. Continuous endeavor such as early detection of cases, early treatment, education on clinical symptoms and prevention of mosquito bites with repellent and mosquito nets will help to reduce the infection rate of malaria in Gangwon-do.

Citations

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  • Epidemiological Characteristics of Re-emerging Vivax Malaria in the Republic of Korea (1993-2017)
    Young Yil Bahk, Hyeong-Woo Lee, Byoung-Kuk Na, Jeonga Kim, Kyoung Jin, Yeong Seon Hong, Tong-Soo Kim
    The Korean Journal of Parasitology.2018; 56(6): 531.     CrossRef
  • Genetic Diversity of Plasmodium vivax Causing Epidemic Malaria in the Republic of Korea
    Young Yil Bahk, Jeonga Kim, Seong Kyu Ahn, Byoung-Kuk Na, Jong-Yil Chai, Tong-Soo Kim
    The Korean Journal of Parasitology.2018; 56(6): 545.     CrossRef
  • Risk analysis of the re-emergence of Plasmodium vivax malaria in Japan using a stochastic transmission model
    Tomoyuki Bitoh, Kaoru Fueda, Hiroshi Ohmae, Mamoru Watanabe, Hirofumi Ishikawa
    Environmental Health and Preventive Medicine.2011; 16(3): 171.     CrossRef
  • Plasmodium vivax PCR genotyping of the first malaria case imported from South Korea into Japan
    Moritoshi Iwagami, Shigeyuki Kano, Ichiro Itoda, Seung-Young Hwang, Weon-Gyu Kho
    Journal of Infection and Chemotherapy.2009; 15(1): 27.     CrossRef
  • ELISA detection of vivax malaria with recombinant multiple stage-specific antigens and its application to survey of residents in endemic areas
    Sera Kim, Hye-Jin Ahn, Tong-Soo Kim, Ho-Woo Nam
    The Korean Journal of Parasitology.2003; 41(4): 203.     CrossRef
  • 7,861 View
  • 64 Download
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Brief Communications

A small-scale survey of intestinal parasite infections among children and adolescents in Legaspi city, the Philippines
Kyu-Jae Lee, Yung-Kyum Ahn, Tai-Soon Yong
Korean J Parasitol 2000;38(3):183-185.
Published online September 30, 2000
DOI: https://doi.org/10.3347/kjp.2000.38.3.183

To determine the status of infection caused by intestinal parasites among children and adolescents living in Legaspi city, the Philippines, we performed a small survey by fecal examination for helminth ova and protozoan cysts with formalin-ether concentration method. Of the 64 examinees, the infection rate was 78.1%. The infection rates of primary school children, preschool children and adolescents were 95.5%, 64.7% and 87.5%, respectively. The infection rate in urban areas was 56%, and 92.3% in rural areas. The infection rates were 51% with Trichuris trichiura, 40% with Ascaris lumbricoides, 23.4% with hookworm, 15.6% with Iodamoeba butschlii, 14.1% with Endolimax nana, 9.4% with Entamoeba coli and 7.8% with Giardia lamblia. There were 33 cases with multiple infection (51.6%). Mixed infection with more than 3 parasites was observed in 15 cases, all of them being children and adolescents living in rural areas. By this survey, it was conjectured that helminthic infection is prevalent among children and adolescents in Legaspi, Philippines.

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    Adilson Fernando Loforte Bauhofer, Idalécia Cossa-Moiane, Selma Marques, Esperança L. Guimarães, Benilde Munlela, Elda Anapakala, Jorfélia J. Chilaúle, Marta Cassocera, Jerónimo S. Langa, Assucênio Chissaque, Júlia Sambo, Lena Manhique-Coutinho, Diocrecia
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    Cecilia Kathure Mbae, David James Nokes, Erastus Mulinge, Joyce Nyambura, Anthony Waruru, Samuel Kariuki
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    The Korean Journal of Parasitology.2003; 41(2): 113.     CrossRef
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Enterobius vermicularis egg positive rate in a primary school in Chungchongnam-do (Province) in Korea
Kyu-Jae Lee, In-Yong Lee, Kyung-il Im
Korean J Parasitol 2000;38(3):177-178.
Published online September 30, 2000
DOI: https://doi.org/10.3347/kjp.2000.38.3.177

The egg positive rate of Enterobius vermicularis was investigated among students of a primary school and a kindergarten located in the rural area of Tangjin-gun, Chungchongnam-do in December, 1998. Of the 189 examinees, 28 (14.8%) were found to be infected with E. vermicularis by the adhesive cellotape anal swab method. The infection rates ranged from 4.2% to 26.1% among school children, and the highest rate was observed in children attending kindergarten. Three months after treatment with albendazole, four (14.3%) out of 28 infected children still remained infected with E. vermicularis. Through this survey, we were able to determine that E. vermicularis infection is still prevalent among children in rural areas of Korea.

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    H. S. Al-Warid, A. Q. I. Alqaisi, I. M. Al Saqur, H. S. Al-Bahadely
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    Eman H. Radwan, Amel Abd El Rahman Hassan, Wael M. Lotfy, Ahmed Abd El-Mawgood, Hala M. Mashaal, Patricio De los RÃos
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  • Comparison of Egg Positive Rates ofEnterobius vermicularisamong Preschool Children in Three Korean Localities
    Sung-Hee Hong, Sang-Eun Lee, Young-Il Jeong, Won-Ja Lee, Shin-Hyeong Cho
    The Korean Journal of Parasitology.2011; 49(4): 441.     CrossRef
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    Betina C Pezzani
    World Journal of Gastroenterology.2004; 10(17): 2535.     CrossRef
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    Bong Jin Kim, Bo Young Lee, Hyun Kee Chung, Young Sun Lee, Kun Hee Lee, Hae Jin Chung, Mee Sun Ock
    The Korean Journal of Parasitology.2003; 41(1): 75.     CrossRef
  • Enterobius vermicularis egg positive rates in primary school children in Gangwon-do (Province), Korea
    Kyu-Jae Lee, Yung-Kyum Ahn, Yong-Suk Ryang
    The Korean Journal of Parasitology.2001; 39(4): 327.     CrossRef
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Case Report
An incidental case of human Heterophyes nocens infection diagnosed by sectional morphology in a biopsy specimen of the small intestine
Yong-Suk Ryang, Chi-Young Lee, Kyu-Jae Lee, Soon-Hyung Lee, Jong-Yil Chai
Korean J Parasitol 1999;37(3):189-194.
Published online September 30, 1999
DOI: https://doi.org/10.3347/kjp.1999.37.3.189

A case of human infection with Heterophyes nocens (Heterophyidae) was incidentally found in a biopsy specimen of the Meckel's diverticulum at the upper part of the small intestine. The patient was a 58-year-old man living in a rural area of Talsong-gun, Kyongsangbuk-do. He had gastrointestinal symptoms such as epigastric pain, indigestion, and abdominal discomfort for 3 months, and severe diarrhea, abdominal pain, and vomiting for about 1 month before hospitalization. Endoscopy of the upper part of the small intestine revealed a Meckel's diverticulum, and it was excised and histopathologically examined. Three adult flukes were incidentally found sectioned in the mucosa, and they were identified as H. nocens. The patient had a history of eating raw mullets at a fish market in Pusan 6 months ago, and the mullets were presumed to be the source of infection. This case brings a considerable interest in that specific diagnosis of heterophyid infections could be done by sectional morphology of the worms.

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