Theileria annulata, a protozoan parasite of cattle and domestic buffaloes, is transmitted by ticks of the genus Hyalomma, and causes a disease named Mediterranean or tropical theileriosis. In this research 50 cattle naturally infected with Theileria annulata were treated with the extract of the plant Peganum harmala. The treatment was continued for 5 days, the dose of the extract being 5 mg/kg per day. After the treatment, 39 cattle responded to the treatment and recovered, but 11 did not respond to the treatment and died. The recovery rate of animals treated with the extract of the plant Peganum harmala was 78%.
Citations
Citations to this article as recorded by
Metabolic profiling reveals first evidence of fumigating drug plant Peganum harmala in Iron Age Arabia Barbara Huber, Marta Luciani, Ahmed M. Abualhassan, Daniel Giddings Vassão, Ricardo Fernandes, Thibaut Devièse Communications Biology.2025;[Epub] CrossRef
Therapeutic evaluation of Buparvaquone and Peganum harmala against theileriosis in cattle S. A. Lokhande, M. F. M. F. Siddiqui, M. P. Sakhare, G. M. Chigure, N. D. Jadhav, S. Sajid Ali, S. D. Chepte, S. R. Shaikh, P. C. Ahire Tropical Animal Health and Production.2025;[Epub] CrossRef
In vivo investigation of the inhibitory effect of Peganum harmala L. and its major alkaloids on ethylene glycol-induced urolithiasis in rats Summya Rashid, Maryam Sameti, Mohammed H. Alqarni, Fatma M. Abdel Bar Journal of Ethnopharmacology.2023; 300: 115752. CrossRef
Prevalence and risk factors assessment of theileriosis in livestock of Malakand Division, Pakistan Mohsinullah Mohsin, Khalid Hameed, Mustafa Kamal, Asad Ali, Naseem Rafiq, Tahir Usman, Wali Khan, Ansar Ahmed Abbasi, Rahmat Ullah Khan, Gulalai Jamal Yousafzai Journal of the Saudi Society of Agricultural Sciences.2022; 21(4): 242. CrossRef
Antibacterial, Antifungal, Antiviral, and Antiparasitic Activities of Peganum harmala and Its Ingredients: A Review Zihao Zhu, Shujuan Zhao, Changhong Wang Molecules.2022; 27(13): 4161. CrossRef
Synthesis and structure-activity relationships of asymmetric dimeric β-carboline derivatives as potential antitumor agents Liang Guo, Wei Chen, Rihui Cao, Wenxi Fan, Qin Ma, Jie Zhang, Bin Dai European Journal of Medicinal Chemistry.2018; 147: 253. CrossRef
In vitro ovicidal activity of Peganum harmala seeds extract on the eggs of Fasciola hepatica
Mohammad Moazeni, Zahra Sadat Saadaty Ardakani, Mohammad Jamal Saharkhiz, Jafar Jalaei, Ali Asghar Khademolhoseini, Shahab Shams Esfand Abad, Amir Mootabi Alavi Journal of Parasitic Diseases.2017; 41(2): 467. CrossRef
A review on traditional uses, phytochemistry, pharmacology, pharmacokinetics and toxicology of the genus Peganum Shuping Li, Xuemei Cheng, Changhong Wang Journal of Ethnopharmacology.2017; 203: 127. CrossRef
Ultrastructure of Theileria-infected blood cells of loggerhead turtles Alessandra Pica Comparative Clinical Pathology.2015; 24(4): 711. CrossRef
Prevalence of theileriosis in cross-bred cattle: its detection through blood smear examination and polymerase chain reaction in Dehradun district, Uttarakhand, India Shweta Kohli, U. K. Atheya, A. Thapliyal Veterinary World.2014; 7(3): 168. CrossRef
Medicinal plants as alternative for control of livestock parasites. 2. Protozoa M B CHHABRA, K M L PATHAK, K MURALEEDHARAN The Indian Journal of Animal Sciences.2014;[Epub] CrossRef
Evaluation of Haematochemical Parameters in Crossbred Cattle Naturally Infected with Theileria annulata in Iran A.P.R. Saber, M. Khorrami, M. Nouri International Journal of Dairy Science.2008; 3(4): 205. CrossRef
For evaluation of the prevalence of Cryptosporidium sp. infection in diarrheic and non-diarrheic humans in Iran, fecal specimens from diarrheic (n = 129) and non-diarrheic humans (n = 271) were collected and examined for the presence of Cryptosporidium sp. oocysts. The presence of Cryptosporidium sp. oocysts was determined by Ziehl-Neelsen acid-fast staining. Humans were grouped according to their age as follows: younger than 15, 16-25, 26-35, 36-50, and over 51 years. The results showed that the overall prevalence of infection in all 400 samples was 10.8%, but the prevalence (25.6%) in diarrheic humans was higher than that (3.7%) in non-diarrheic humans. Oocysts of Cryptosporidium sp. were detected in the feces of 21.4%, 9.3%, 8.8%, 6.7% and 5.7% of different age groups, respectively. The intensity of oocysts was significantly higher in diarrheic humans than in non-diarrheic ones. There was a significant association between Cryptosporidium sp. infection and occurrence of diarrhea (P < 0.05). The results indicate that Cryptosporidium sp. infection is prevalent in diarrheic humans in Iran.
Citations
Citations to this article as recorded by
Cryptosporidium Species Infections Detected from Fecal Samples of Animal and Human Hosts in South Africa: Systematic Review and Meta-Analysis Mpho Tawana, ThankGod E. Onyiche, Tsepo Ramatla, Sebolelo Jane Nkhebenyane, Dennis J. Grab, Oriel Thekisoe Microorganisms.2024; 12(12): 2426. CrossRef
Enteric protozoal infections in camels: Etiology, epidemiology, and future perspectives Eman A. Noaman, Mohamed Nayel, Akram Salama, Mona A. Mahmoud, Adel M. El-Kattan, Ali S. Dawood, Ibrahim S. Abd El-Hamid, Ahmed Elsify, Walid Mousa, Ahmed Elkhtam, Ahmed Zaghawa German Journal of Veterinary Research.2023; 3(1): 1. CrossRef
Treatment of Urticaria caused by severe cryptosporidiosis in a 17-month-old child – a case report Mehdi Azami, Saeid Amini Rarani, Fatemeh Kiani BMC Infectious Diseases.2023;[Epub] CrossRef
A large-scale study on the prevalence of intestinal parasites in patients referred to medical laboratories in Urmia, Northwest Iran Shiva Zeinali, Mahsa Rezgi, Morteza Gholinejad, Rasool Jafari BMC Gastroenterology.2023;[Epub] CrossRef
Prevalence and Molecular Genotyping of Cryptosporidium Spp. in Diarrheic Patients from Bandar Abbas City, Southern Iran Majid Najafi-Asl, Habibollah Faraji, Saeed Hosseini Teshnizi, Khojasteh Sharifi-Sarasiabi Jundishapur Journal of Microbiology.2020;[Epub] CrossRef
Evaluation of prevalence and risk factors associated with Cryptosporidium infection in rural population of district Buner, Pakistan Asar Khan, Sumaira Shams, Saima Khan, Muhammad Iftikhar Khan, Sardar Khan, Abid Ali, Adriana Calderaro PLOS ONE.2019; 14(1): e0209188. CrossRef
Cryptosporidium parvum in Children with Diarrhea in Zahedan, Iran Faezeh Mirshekari, Kareem Hatam-Nahavandi, Samane Abdolahi Khabisi, Alireza Salimi-Khorashad Jundishapur Journal of Microbiology.2019;[Epub] CrossRef
Rodent-borne diseases and their public health importance in Iran Mohammad Hasan Rabiee, Ahmad Mahmoudi, Roohollah Siahsarvie, Boris Kryštufek, Ehsan Mostafavi, Peter J. Krause PLOS Neglected Tropical Diseases.2018; 12(4): e0006256. CrossRef
Prevalence and associated risk factors of intestinal parasitic infections in Kurdistan province, northwest Iran Fares Bahrami, Ali Haghighi, Ghasem Zamini, Mohammad Bagher Khadem-Erfan, Eznolla Azargashb, Andrew Kiyu Cogent Medicine.2018; 5(1): 1503777. CrossRef
Human cryptosporidiosis in Iran: a systematic review and meta-analysis Reza Berahmat, Adel Spotin, Ehsan Ahmadpour, Mahmoud Mahami-Oskouei, Azim Rezamand, Nayyereh Aminisani, Morteza Ghojazadeh, Roghayeh Ghoyounchi, Tahereh Mikaeili-Galeh Parasitology Research.2017; 116(4): 1111. CrossRef
Expression and Purification of gp40/15 Antigen of Cryptosporidium parvum Parasite in Escherichia coli: an Innovative Approach in Vaccine Production Hossein Sobati, Habib Jasor-Gharebagh, Hossein Honari Iranian Red Crescent Medical Journal.2017;[Epub] CrossRef
Cryptosporidium and Giardia Infections in Children Blandina T. Mmbaga, Eric R. Houpt Pediatric Clinics of North America.2017; 64(4): 837. CrossRef
Epidemiology of cryptosporidium in pediatric diarrheal illnesses Aashima Dabas, Dheeraj Shah, Shinjini Bhatnagar, Rakesh Lodha Indian Pediatrics.2017; 54(4): 299. CrossRef
Burden of major diarrheagenic protozoan parasitic co-infection among amoebic dysentery cases from North East India: a case report JOYOBRATO NATH, GULZAR HUSSAIN, BABY SINGHA, JAISHREE PAUL, SANKAR KUMAR GHOSH Parasitology.2015; 142(10): 1318. CrossRef
Sporozoan Protozoa and Enteroparasites in the Gastroenteritic Patients Referring to the Healthcare Centers of Seven Provinces of Iran Hossein Nahrevanian, Mehdi Assmar, Seyed Mohsen Zahraei, Moharram Mafi, Hossein Masoumi Asl, Fatemeh Sadat Ghasemi International Journal of Enteric Pathogens.2015;[Epub] CrossRef
The first reported cases of human cryptosporidiosis caused by Cryptosporidium hominis in Slovak Republic František Ondriska, Ivana Vrabcová, Silvia Brinďáková, Martin Kváč, Oleg Ditrich, Vojtech Boldiš, Marcela Bastlová Folia Microbiologica.2013; 58(1): 69. CrossRef
Prevalence ofCryptosporidium-like infection in one-humped camels (Camelus dromedarius) of northwestern Iran M. Yakhchali, T. Moradi Parasite.2012; 19(1): 71. CrossRef
Molecular Epidemiology ofCryptosporidiumandGiardiain Humans on Prince Edward Island, Canada: Evidence of Zoonotic Transmission From Cattle E. Budu‐Amoako, S. J. Greenwood, B. R. Dixon, L. Sweet, L. Ang, H. W. Barkema, J. T. McClure Zoonoses and Public Health.2012; 59(6): 424. CrossRef
Ocorrência e fatores de risco da criptosporidiose em felinos de companhia de idosos Cassia Regina Alves Pereira, Aldo Pacheco Ferreira Revista Brasileira de Geriatria e Gerontologia.2012; 15(4): 681. CrossRef
Prevalence and clinical significance of Cryptosporidium infection in patients with hepatitis B virus-associated acute-on-chronic liver failure Zhijian Yu, Fawu Li, Zhongming Zeng, Zheng Huang, Zhang Fan, Yang Jin, Wensheng Luo, Xuandong Xiang, Qiwen Deng International Journal of Infectious Diseases.2011; 15(12): e845. CrossRef
Prevalência de Cryptosporidium spp. em animais domésticos de companhia da população idosa em Teresópolis, Rio de Janeiro, Brasil Cassia R. A. Pereira, Aldo P. Ferreira, Rosalina J. Koifman, Sérgio Koifman Revista Brasileira de Geriatria e Gerontologia.2011; 14(1): 17. CrossRef