Parasites, Hosts and Diseases

"Mohammad Zibaei"

Original Article

Scolicidal Effects of Olea europaea and Satureja khuzestanica Extracts on Protoscolices of Hydatid Cysts: Mohammad Zibaei, Amanallah Sarlak, Bahram Delfan, Behrouz Ezatpour, Alireza Azargoon; Korean J Parasitol 2012;50(1):53-56.
Published online March 6, 2012; DOI: https://doi.org/10.3347/kjp.2012.50.1.53

Abstract
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Treatment of hydatid disease is mainly surgical, with medical treatment being reserved as a coadjuvant treatment. Use of effective scolicidal agents during surgery of cystic echinococcosis is essential to reduce the recurrence rate. The goal of this study was to evaluate the in vitro scolicidal effects of hydroalcoholic extracts of Satureja khuzestanica leaves and aqueous extracts of Olea europaea leaves on hydatid cyst protoscolices. Echinococcus granulosus protoscolices were collected from the liver of sheep infected with the hydatid cyst. Various concentrations of plant extracts were used in different exposure times for viability assay of protoscolices. Among the olive leaf extracts tested, 0.1% and 0.01% concentrations had strong scolicidal effects in 120 min. S. khuzestanica 0.1% had very strong scolicidal effects in 30, 60, and 120 min of exposure times and the mortality rate decreased with the lower concentration. The finding have shown that the scolicidal activity of S. khuzestanica against cystic echinococosis protoscolices were more effective, while the O. europaea extract showed less effects.

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Brief Communication

Experimental Toxocara cati Infection in Gerbils and Rats: Mohammad Zibaei, Seyed Mahmoud Sadjjadi, Shoji Uga; Korean J Parasitol 2010;48(4):331-333.
Published online December 16, 2010; DOI: https://doi.org/10.3347/kjp.2010.48.4.331

Abstract
PDF

Mongolian gerbils and Wistar rats were inoculated orally with 240 and 2,500 Toxocara cati embryonated eggs, respectively, to evaluate the larval recovery in different tissues and organs, such as the liver, lungs, heart, kidney, and skeletal muscles after 5, 30, 49, 70, and 92 days post-infection (PI). Larval recovery rates were 1.7-30.0% in Mongolian gerbils on days 5-92 PI and 0.2-3.8% in rats on the same days. These results indicate that Mongolian gerbils and Wistar rats are suitable experimental paratenic hosts for the study of neurological toxocariasis as well as visceral toxocariasis.

Citations

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