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Mini Review

Signaling Role of NADPH Oxidases in ROS-Dependent Host Cell Death Induced by Pathogenic Entamoeba histolytica
Young Ah Lee, Seobo Sim, Kyeong Ah Kim, Myeong Heon Shin
Korean J Parasitol 2022;60(3):155-161.
Published online June 30, 2022
DOI: https://doi.org/10.3347/kjp.2022.60.3.155
All living organisms are destined to die. Cells, the core of those living creatures, move toward the irresistible direction of death. The question of how to die is critical and is very interesting. There are various types of death in life, including natural death, accidental death, questionable death, suicide, and homicide. The mechanisms and molecules involved in cell death also differ depending on the type of death. The dysenteric amoeba, E. histolytica, designated by the German zoologist Fritz Schaudinn in 1903, has the meaning of tissue lysis; i.e., tissue destroying, in its name. It was initially thought that the amoebae lyse tissue very quickly leading to cell death called necrosis. However, advances in measuring cell death have allowed us to more clearly investigate the various forms of cell death induced by amoeba. Increasing evidence has shown that E. histolytica can cause host cell death through induction of various intracellular signaling pathways. Understanding of the mechanisms and signaling molecules involved in host cell death induced by amoeba can provide new insights on the tissue pathology and parasitism in human amoebiasis. In this review, we emphasized on the signaling role of NADPH oxidases in reactive oxygen species (ROS)-dependent cell death by pathogenic E. histolytica.

Citations

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  • Involvement of NOX2-derived ROS in human hepatoma HepG2 cell death induced by Entamoeba histolytica
    Young Ah Lee, Myeong Heon Shin
    Parasites, Hosts and Diseases.2023; 61(4): 388.     CrossRef
  • 4,638 View
  • 181 Download
  • 1 Web of Science
  • Crossref

Original Articles

Geographical Distribution and Epidemiologic Factors of Chigger Mites on Apodemus agrarius during Autumn in Korea
In Yong Lee, Jae-Won Lim, Jang Hoon Seo, Heung Chul Kim, Ku Jae Lee, Tai-Soon Yong, Won-Ja Lee, Jae-Ran Yu, Seobo Sim
Korean J Parasitol 2021;59(5):473-479.
Published online October 22, 2021
DOI: https://doi.org/10.3347/kjp.2021.59.5.473
A nationwide survey of chigger mites causing scrub typhus and an investigation of epidemiologic factors for chigger mites was conducted at 16 localities in 8 provinces in Korea during autumn 2009, 2012, and 2013. A total of 233 Apodemus agrarius were captured, and all were infested with chigger mites. The chigger index was highest in Chungcheongbuk-do in 2009 (358.3) and 2012 (290.1) and Chungcheongnam-do in 2013 (294.4). The predominant chigger mite species was Leptotrombidium pallidum in the northern and central parts and L. scutellare in the southern and western parts, Korea. L. pallidum was not found in Jellanam-do and Gyeongsangnam-do and the distribution of L. scutellare had been expanded in the northern parts of Korea. The chigger index of L. pallidum was positively correlated with temperature and negatively correlated with humidity. The incidence of scrub typhus is dependent on L. scutellare index. These findings could be helpful to monitor the distribution of chigger mites and to develop a preventive measures for scrub typhus in Korea.

Citations

Citations to this article as recorded by  Crossref logo
  • Scrub typhus update: A re‑emerging global threat beyond the Tsutsugamushi Triangle and the physiological ramifications of scrub typhus infection (Review)
    Ankur Vashishtha, Vivek Kumar, Gautam Panwar, Gaurav Kausik, Samaniya Baig, Prigya Sharma, Rajesh Yadav
    World Academy of Sciences Journal.2025;[Epub]     CrossRef
  • The Association Between Environmental Factors and Scrub Typhus: A Review
    Shu Yang, Shu Yang, Yuxiang Xie, Wenjing Duan, Yiting Cui, Ai Peng, Yisheng Zhou, Yibing Fan, Hui Li, Peng Huang
    Tropical Medicine and Infectious Disease.2025; 10(6): 151.     CrossRef
  • Temperature effect on scrub typhus incidence in South Korea: the projection for climate change
    Donghee Seo, Yoon-Jung Choi, Yun-Chul Hong
    Postgraduate Medical Journal.2025;[Epub]     CrossRef
  • Associations of meteorological factors and dynamics of scrub typhus incidence in South Korea: A nationwide time-series study
    Taehee Chang, Kyung-Duk Min, Sung-il Cho, Yoonhee Kim
    Environmental Research.2024; 245: 117994.     CrossRef
  • The impact of meteorological parameters on the scrub typhus incidence in Baoshan City, western Yunnan, China
    Yun-Yan Luo, Alan Frederick Geater, Jia-Xiang Yin
    Frontiers in Public Health.2024;[Epub]     CrossRef
  • Prevalence of chigger mites and Orientia tsutsugamushi strains in northern regions of Gangwon-do, Korea
    Soojin Kim, In Yong Lee, Sezim Monoldorova, Jiro Kim, Jang Hoon Seo, Tai-Soon Yong, Bo Young Jeon
    Parasites, Hosts and Diseases.2023; 61(3): 263.     CrossRef
  • Molecular Identification of Bacillus Isolated from Korean Water Deer (Hydropotes inermis argyropus) and Striped Field Mouse (Apodemus agrarius) Feces by Using an SNP-Based 16S Ribosomal Marker
    Md-Mafizur Rahman, Sang-Jin Lim, Yung-Chul Park
    Animals.2022; 12(8): 979.     CrossRef
  • 5,410 View
  • 132 Download
  • 7 Web of Science
  • Crossref
Effectiveness of Mass Drug Administration on Neglected Tropical Diseases in Schoolchildren in Zanzibar, Tanzania
Ju Yeong Kim, Seobo Sim, Eun Joo Chung, Han-Jong Rim, Jong-Yil Chai, Duk-Young Min, Keeseon S. Eom, Khalfan A. Mohammed, Iddi S. Khamis, Tai-Soon Yong
Korean J Parasitol 2020;58(2):109-119.
Published online April 30, 2020
DOI: https://doi.org/10.3347/kjp.2020.58.2.109
Soil-transmitted helminths and Schistosoma haematobium affect more than 3 billion people globally and mainly occur in sub-Saharan Africa. The present study assessed the overall infection status of a 1716-student cohort of school-children in Zanzibar and applied mass drug administration (MDA) to the cohort from 2007 to 2009. Schools in Pemba, Zanzibar, had a much higher prevalence of soil-transmitted helminth infections than those in Unguja, and the Chaani, Ghana, and Machui schools of Unguja exhibited high S. haematobium infection rates. The MDA program only partially controlled parasite infections, owing to high rates of re-infection. The infection rate of S. haematobium across all 10 schools, for example, was only reduced by 1.8%, and even this change not significant, even though the S. haematobiuminfection rates of the Chaani and Mzambarauni schools were significantly reduced from 64.4 and 23.4%, respectively, at the first screening, to 7.3 and 2.3% at the last screening. The overall infection rate of Ascaris lumbricoides was reduced from 36.0% at the first screening to 22.6% at the last screening. However, the infection rates for both Trichuris trichiuraand hookworm were generally unaffected by MDA. In the future, parasite control programs should involve strategically designed MDA schedules and holistic intervention (e.g., sanitation improvement, hygiene behavior changes, and control of intermediated hosts).

Citations

Citations to this article as recorded by  Crossref logo
  • Effects of paediatric schistosomiasis control programmes in sub-Saharan Africa: A systematic review
    Maryline Vere, Wilma ten Ham-Baloyi, Paula Ezinne Melariri, Raquel Inocencio da Luz
    PLOS ONE.2024; 19(5): e0301464.     CrossRef
  • Soil-transmitted helminth (STH) infections in the Wolaita zone in Southern Ethiopia: mid-stage evaluation of the Geshiyaro project and progress towards the interruption of transmission
    Birhan Mengistu, Ewnetu Firdawek Liyew, Melkie Chernet, Geremew Tasew, Rosie Maddren, Benjamin Collyer, Ufaysa Anjulo, Adugna Tamiru, Kathryn Forbes, Zelalem Mehari, Kebede Deribe, Teshale Yadeta, Mihretab Salasibew, Getachew Tollera, Roy Anderson
    Parasites & Vectors.2024;[Epub]     CrossRef
  • Parasitic helminth infections in humans modulate Trefoil Factor levels in a manner dependent on the species of parasite and age of the host
    Babatunde Adewale, Jonathan R. Heintz, Christopher F. Pastore, Heather L. Rossi, Li-Yin Hung, Nurudeen Rahman, Jeff Bethony, David Diemert, James Ayorinde Babatunde, De’Broski R. Herbert, Subash Babu
    PLOS Neglected Tropical Diseases.2021; 15(10): e0009550.     CrossRef
  • 7,571 View
  • 181 Download
  • 4 Web of Science
  • Crossref

Brief Communication

Indoor Occurrence of the Ghost Ant Tapinoma melanocephalum (Hymenoptera: Formicidae) in Urban Homes in Korea
In Yong Lee, Seong Joon Park, Jang Hoon Seo, Seobo Sim, Jin-Hwan Kim, Young Gon Gwon, Tai-Soon Yong
Korean J Parasitol 2017;55(2):225-228.
Published online April 30, 2017
DOI: https://doi.org/10.3347/kjp.2017.55.2.225
The ghost ant Tapinoma melanocephalum is a common household pest worldwide. The present study examined the occurrence of the species in urban homes in Korea. During the period of September 2014 to January 2016, T. melanocephalum workers were collected from 58 homes at 29 different localities using bait traps with 10% sugar solution. The species was widely distributed throughout urban homes at 29 different localities, and the indoor occurrence of T. melanocephalum was highest in Seoul (32.7%) and metropolitan areas of Gyeonggi-do (Province) (29.3%). The indoor incidence rate of T. melanocephalum peaked in September (22.8%), remained moderate from October through April, and peaked again in May (15.7%). In contrast, a low incidence was observed from June to August (7.0%). The present study provides evidence that native ants, such as T. melanocephalum, are potential indoor pests of homes in Korea throughout the year.

Citations

Citations to this article as recorded by  Crossref logo
  • Ant invasion in China: An in-depth analysis of the country's ongoing battle with exotic ants
    Junaid Ali Siddiqui, Bamisope Steve Bamisile, Ruidong Fan, Muhammad Hafeez, Waqar Islam, Wenjia Yang, Minyi Wei, Hao Ran, Yijuan Xu, Xiaoyulong Chen
    Ecological Indicators.2024; 160: 111811.     CrossRef
  • Exotic Ants of the Asia-Pacific: Invasion, National Response, and Ongoing Needs
    Yijuan Xu, Edward L. Vargo, Kazuki Tsuji, Ross Wylie
    Annual Review of Entomology.2022; 67(1): 27.     CrossRef
  • 9,171 View
  • 132 Download
  • 2 Web of Science
  • Crossref

Original Article

Simultaneous Molecular Detection of Cryptosporidium and Cyclospora from Raw Vegetables in Korea
Seobo Sim, Jua Won, Jae-Whan Kim, Kyungjin Kim, Woo-Yoon Park, Jae-Ran Yu
Korean J Parasitol 2017;55(2):137-142.
Published online April 30, 2017
DOI: https://doi.org/10.3347/kjp.2017.55.2.137
Cryptosporidium and Cyclospora are well-known coccidian protozoa that can cause waterborne and foodborne diarrheal illnesses. There have been a few reports regarding contamination in different vegetables with Cryptosporidium, but no data are available regarding the sources of Cyclospora infections in Korea. In the present study, we collected 6 kinds of vegetables (perilla leaves, winter-grown cabbages, chives, sprouts, blueberries, and cherry tomatoes) from July 2014 to June 2015, and investigated contamination by these 2 protozoa using multiplex quantitative real-time PCR. Among 404 vegetables, Cryptosporidium and Cyclospora were detected in 31 (7.7%) and 5 (1.2%) samples, respectively. In addition, Cryptosporidium was isolated from all 6 kinds of vegetables, whereas Cyclospora was detected in 4 kinds of vegetables (except perilla leaves and chives). Cryptosporidium (17.8%) and Cyclospora (2.9%) had the highest detection rates in chives and winter-grown cabbages, respectively. Cryptosporidium was detected all year long; however, Cyclospora was detected only from October to January. In 2 samples (sprout and blueberry), both Cryptosporidium and Cyclospora were detected. Further investigations using TaqI restriction enzyme fragmentation and nested PCR confirmed Cryptosporidium parvum and Cyclospora cayetanensis, respectively. In conclusion, we detected C. cayetanensis in vegetables for the first time in Korea. This suggests that screening should be employed to prevent these protozoal infections in Korea.

Citations

Citations to this article as recorded by  Crossref logo
  • Cryptosporidium and cryptosporidiosis: An update of Asian perspectives in humans, water and food, 2015–2025
    Shahira Abdelaziz Ali Ahmed, Sonia Boughattas, Mohammad Reza Mahmoudi, Huma Khan, Simuzar Mamedova, Ardra Namboodiri, Frederick R. Masangkay, Panagiotis Karanis
    Current Research in Parasitology & Vector-Borne Diseases.2025; 8: 100311.     CrossRef
  • Cyclospora in humans, animals, fresh produce and water in China: implications for host specificity of Cyclospora species and zoonotic transmission of C. cayetanensis
    Kangli Feng, Yaqiong Guo, Na Li, Lihua Xiao, Yaoyu Feng
    One Health Advances.2025;[Epub]     CrossRef
  • Cryptosporidium and agriculture: A review
    Eleni Golomazou, Simuzer Mamedova, Aida Vafae Eslahi, Panagiotis Karanis
    Science of The Total Environment.2024; 916: 170057.     CrossRef
  • Unveiling risks in healthy food: Vegetables and fruits are linked to the distribution chain of protozoan parasites
    Aida Vafae Eslahi, Simuzer Mamedova, Reghaissia Nassiba, Panagiotis Karanis
    Food Microbiology.2024; 123: 104592.     CrossRef
  • Food and Waterborne Cryptosporidiosis from a One Health Perspective: A Comprehensive Review
    Munwar Ali, Yaru Ji, Chang Xu, Qazal Hina, Usama Javed, Kun Li
    Animals.2024; 14(22): 3287.     CrossRef
  • Loop mediated isothermal amplification for detection of foodborne parasites: A journey from lab to lab-on-a-chip
    Fatemeh Mahdavi Abhari, Maryam Niyyati, Hamid Assadzadeh Aghdaei, Hamed Mirjalali
    Food Control.2023; 143: 109251.     CrossRef
  • Health risks of Cryptosporidium and Giardia in the application of surface water and septic tank effluent in Chinese agriculture: Impact on cancer patients identified by quantitative microbial risk assessment
    Qian Huang, Shan Huang, Weijie Kuang, Jianghui Yi, Shunxin Xiao, Feng Zhao, Guosheng Xiao
    Food Microbiology.2023; 111: 104213.     CrossRef
  • Development of a new multiplex PCR to detect fecal coccidian parasite
    Manish Katiyar, Reena Gulati, Nonika Rajkumari, Rakesh Singh
    Indian Journal of Gastroenterology.2023; 42(2): 241.     CrossRef
  • Contamination of fresh produce sold on the Italian market with Cyclospora cayetanensis and Echinococcus multilocularis
    Alessandra Barlaam, Tamirat T. Temesgen, Kristoffer R. Tysnes, Laura Rinaldi, Nicola Ferrari, Anna R. Sannella, Giovanni Normanno, Simone M. Cacciò, Lucy J. Robertson, Annunziata Giangaspero
    Food Microbiology.2021; 98: 103792.     CrossRef
  • Detection of Cyclospora cayetanensis on bagged pre-cut salad mixes within their shelf-life and after sell by date by the U.S. food and drug administration validated method
    Sonia Almeria, Alicia Shipley
    Food Microbiology.2021; 98: 103802.     CrossRef
  • Diverse Genotypes and Species of Cryptosporidium in Wild Rodent Species from the West Coast of the USA and Implications for Raw Produce Safety and Microbial Water Quality
    Xunde Li, Edward Robert Atwill
    Microorganisms.2021; 9(4): 867.     CrossRef
  • Detection of Cyclospora cayetanensis, Echinococcus multilocularis, Toxocara spp. and microsporidia in fresh produce using molecular methods: – A review
    B. Bartosova, B. Koudela, I. Slana
    Food and Waterborne Parasitology.2021; 23: e00124.     CrossRef
  • Causes of acute gastroenteritis in Korean children between 2004 and 2019
    Eell Ryoo
    Clinical and Experimental Pediatrics.2021; 64(6): 260.     CrossRef
  • An Epidemiological and Diagnostic Study of Cyclospora Cayetanensis Parasite in Anbar Province - Iraq
    S S Shahatha, S A Alkubaisy, M O Mousa
    IOP Conference Series: Earth and Environmental Science.2021; 904(1): 012026.     CrossRef
  • Evaluation of the U.S. Food and Drug Administration validated molecular method for detection of Cyclospora cayetanensis oocysts on fresh and frozen berries
    Angela Assurian, Helen Murphy, Laura Ewing, Hediye Nese Cinar, Alexandre da Silva, Sonia Almeria
    Food Microbiology.2020; 87: 103397.     CrossRef
  • A Molecular Tool for Rapid Detection and Traceability of Cyclospora cayetanensis in Fresh Berries and Berry Farm Soils
    Carolina N. Resendiz-Nava, Guadalupe E. Orozco-Mosqueda, Edmundo M. Mercado-Silva, Susana Flores-Robles, Hilda V. Silva-Rojas, Gerardo M. Nava
    Foods.2020; 9(3): 261.     CrossRef
  • Parasite detection in food: Current status and future needs for validation
    Rachel M. Chalmers, Lucy J. Robertson, Pierre Dorny, Suzanne Jordan, Age Kärssin, Frank Katzer, Stéphanie La Carbona, Marco Lalle, Brian Lassen, Ivona Mladineo, Miroslaw Rozycki, Ewa Bilska-Zajac, Gereon Schares, Anne Mayer-Scholl, Chiara Trevisan, Kristo
    Trends in Food Science & Technology.2020; 99: 337.     CrossRef
  • Detection of Cryptosporidium oocysts and Giardia cysts in vegetables from street markets from the Qinghai Tibetan Plateau Area in China
    Xiuping Li, Xueyong Zhang, Yingna Jian, Geping Wang, Liqing Ma, Chad Schou, Panagiotis Karanis
    Parasitology Research.2020; 119(6): 1847.     CrossRef
  • Comparison of commercial and in-house real-time PCR platforms for 15 parasites and microsporidia in human stool samples without a gold standard
    Thomas Köller, Andreas Hahn, Enkhtsetseg Altangerel, Jaco J. Verweij, Olfert Landt, Simone Kann, Denise Dekker, Jürgen May, Ulrike Loderstädt, Andreas Podbielski, Hagen Frickmann
    Acta Tropica.2020; 207: 105516.     CrossRef
  • Prevalence of Cryptosporidium and Giardia in vegetables in Iran: a nineteen-years meta-analysis review
    Ehsan Javanmard, Elnaz Sadat Mirsamadi, Meysam Olfatifar, Erfan Ghasemi, Fatemeh Saki, Hamed Mirjalali, Mohammad Reza Zali, Panagiotis Karanis
    Journal of Environmental Health Science and Engineering.2020; 18(2): 1629.     CrossRef
  • Detection of human intestinal protozoan parasites in vegetables and fruits: a review
    Junqiang Li, Zhenzhen Wang, Md Robiul Karim, Longxian Zhang
    Parasites & Vectors.2020;[Epub]     CrossRef
  • Human cyclosporiasis
    Annunziata Giangaspero, Robin B Gasser
    The Lancet Infectious Diseases.2019; 19(7): e226.     CrossRef
  • Simultaneous detection of four protozoan parasites on leafy greens using a novel multiplex PCR assay
    Karen Shapiro, Minji Kim, Veronica B. Rajal, Michael J. Arrowood, Andrea Packham, Beatriz Aguilar, Stefan Wuertz
    Food Microbiology.2019; 84: 103252.     CrossRef
  • Status of common parasitic diseases in Korea in 2019
    Sun Huh
    Journal of the Korean Medical Association.2019; 62(8): 437.     CrossRef
  • Genotyping genetically heterogeneousCyclospora cayetanensisinfections to complement epidemiological case linkage
    Joel L. N. Barratt, Subin Park, Fernanda S. Nascimento, Jessica Hofstetter, Mateusz Plucinski, Shannon Casillas, Richard S. Bradbury, Michael J. Arrowood, Yvonne Qvarnstrom, Eldin Talundzic
    Parasitology.2019; 146(10): 1275.     CrossRef
  • Identification of human pathogenic Enterocytozoon bieneusi, Cyclospora cayetanensis, and Cryptosporidium parvum on the surfaces of vegetables and fruits in Henan, China
    Junqiang Li, Ke Shi, Fangfang Sun, Tingwen Li, Rongjun Wang, Sumei Zhang, Fuchun Jian, Changshen Ning, Longxian Zhang
    International Journal of Food Microbiology.2019; 307: 108292.     CrossRef
  • Cyclospora cayetanensis and Cyclosporiasis: An Update
    Sonia Almeria, Hediye N. Cinar, Jitender P. Dubey
    Microorganisms.2019; 7(9): 317.     CrossRef
  • Cryptosporidium spp., prevalence, molecular characterisation and socio-demographic risk factors among immigrants in Qatar
    Sonia Boughattas, Jerzy M. Behnke, Duaa Al-Sadeq, Ahmed Ismail, Marawan Abu-Madi, Christine A. Petersen
    PLOS Neglected Tropical Diseases.2019; 13(10): e0007750.     CrossRef
  • Molecular Prevalence and Genotypes of Cryptosporidium parvum and Giardia duodenalis in Patients with Acute Diarrhea in Korea, 2013-2016
    Da-Won Ma, Myoung-Ro Lee, Sung-Hee Hong, Shin-Hyeong Cho, Sang-Eun Lee
    The Korean Journal of Parasitology.2019; 57(5): 531.     CrossRef
  • Assessment of pesticide residues and microbial contamination in raw leafy green vegetables marketed in Italy
    Gino Angelo Santarelli, Giacomo Migliorati, Francesco Pomilio, Cristina Marfoglia, Patrizia Centorame, Antonella D'Agostino, Roberta D'Aurelio, Rossana Scarpone, Noemi Battistelli, Federica Di Simone, Giuseppe Aprea, Luigi Iannetti
    Food Control.2018; 85: 350.     CrossRef
  • Parasite contamination of berries: Risk, occurrence, and approaches for mitigation
    Tamirat Tefera, Kristoffer R. Tysnes, Kjersti Selstad Utaaker, Lucy J. Robertson
    Food and Waterborne Parasitology.2018; 10: 23.     CrossRef
  • 11,505 View
  • 281 Download
  • 33 Web of Science
  • Crossref

Brief Communication

Prevalence of Cryptosporidium Infection among Inhabitants of 2 Rural Areas in White Nile State, Sudan
Seobo Sim, Jae-Ran Yu, Young-Ha Lee, Jin-Su Lee, Hoo-Gn Jeong, Abd Al Wahab Saed Mohamed, Sung-Tae Hong
Korean J Parasitol 2015;53(6):745-747.
Published online December 31, 2015
DOI: https://doi.org/10.3347/kjp.2015.53.6.745
Cryptosporidium, a protozoan parasite that causes watery diarrhea, is found worldwide and is common in areas with low water hygiene. In February 2014, 866 stool samples were collected from the inhabitants of 2 rural areas in White Nile State, Sudan. These stool samples were assessed by performing modified acid-fast staining, followed by examination under a light microscope. The overall positive rate of Cryptosporidium oocysts was 13.3%. Cryptosporidium oocysts were detected in 8.6% stool samples obtained from inhabitants living in the area having water purification systems and in 14.6% stool samples obtained from inhabitants living in the area not having water purification systems. No significant difference was observed in the prevalence of Cryptosporidium infection between men and women (14.7% and 14.1%, respectively). The positive rate of oocysts by age was the highest among inhabitants in their 60s (40.0%). These findings suggest that the use of water purification systems is important for preventing Cryptosporidium infection among inhabitants of these rural areas in Sudan.

Citations

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  • Cryptosporidium spp. prevalence in the general population in Guinea: first large-scale screening study
    Timothé Guilavogui, Nausicaa Gantois, Jérémy Desramaut, Fode Ibrahima Cissé, Salif Cherif Touré, Bakary Luther Kourouma, Cristian Preda, Magali Chabé, Eric Viscogliosi, Gabriela Certad
    Parasite.2024; 31: 70.     CrossRef
  • Prevalence of cryptosporidiosis among children with diarrhoea under five years admitted to Kosti teaching hospital, Kosti City, Sudan
    Abdelhakam G. Tamomh, AbdElhadi M. Agena, Elham Elamin, Mohammed A. Suliman, Mohammed Elmadani, Asmaa B. Omara, Sahar A. Musa
    BMC Infectious Diseases.2021;[Epub]     CrossRef
  • First report and molecular characterization of Cryptosporidium spp. in humans and animals in Khartoum state, Sudan
    Kaltoum Yagoub Adam, A. A. Ismail, M. A. Masri, A. A. Gameel
    Veterinary World.2019; 12(1): 183.     CrossRef
  • Epidemiological Survey on Schistosomiasis and Intestinal Helminthiasis among Village Residents of the Rural River Basin Area in White Nile State, Sudan
    Young-Ha Lee, Jin-Su Lee, Hoo-Gn Jeoung, In-Sun Kwon, Abd Al Wahab Saed Mohamed, Sung-Tae Hong
    The Korean Journal of Parasitology.2019; 57(2): 135.     CrossRef
  • Cryptosporidium and Giardia in Africa: current and future challenges
    Sylvia Afriyie Squire, Una Ryan
    Parasites & Vectors.2017;[Epub]     CrossRef
  • Cryptosporidium spp. and rotavirus gastroenteritis and change of incidence after rotavirus vaccination among children in Raparin Pediatrics Hospital, Erbil, Iraq
    Sally S. Azeez, Hadi M. Alsakee
    Medical Journal of Indonesia.2017; 26(3): 190.     CrossRef
  • 9,196 View
  • 97 Download
  • 6 Web of Science
  • Crossref

Case Report

Human Sting of Cephalonomia gallicola (Hymenoptera: Bethylidae) in Korea
In-Yong Lee, Chang-Seob Shin, Seobo Sim, Jung-Won Park, Tai-Soon Yong
Korean J Parasitol 2014;52(6):681-684.
Published online December 23, 2014
DOI: https://doi.org/10.3347/kjp.2014.52.6.681

Hymenoptera stings can cause serious injury to humans. We report the clinical findings of 6 cases of Hymenoptera stings. All patients developed painful erythematous papules at the sting sites and had a past history of parasitoid wasp sting. This is the first clinical report of the parasitoid wasp, Cephalonomia gallicola, causing human stings in Korea.

Citations

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  • Human ectoparasitoses caused by flat wasps of the genera Sclerodermus and Cephalonomia (Hymenoptera: Bethylidae)
    Paolo Masini, Luca Stingeni, Gianandrea Salerno, Valerio Saitta, Celso O Azevedo, Manuela Rebora, Matteo Ornielli, Katharina Hansel, Leonardo Bianchi, Gabriele Casciola
    Clinical and Experimental Dermatology.2025; 50(8): 1508.     CrossRef
  • Updated checklist of Iranian Bethylidae (Hymenoptera: Chrysidoidea)
    Hassan Ghahari, Jongok Lim
    Oriental Insects.2019; 53(1): 112.     CrossRef
  • Health Hazards Associated with Arthropod Infestation of Stored Products
    Jan Hubert, Vaclav Stejskal, Christos G. Athanassiou, James E. Throne
    Annual Review of Entomology.2018; 63(1): 553.     CrossRef
  • A Review of Sclerodermus Latreille, 1809 (Hymenoptera: Bethylidae) Infestations and Report of the First Case in North America North of Mexico
    Michael J Skvarla
    Journal of Medical Entomology.2018; 55(3): 752.     CrossRef
  • Bethylids attacking stored‐product pests: an overview
    Marco Amante, Matthias Schöller, Pompeo Suma, Agatino Russo
    Entomologia Experimentalis et Applicata.2017; 163(3): 251.     CrossRef
  • Dermatitis caused by arthropods in domestic environment: an Italian multicentre study
    L. Stingeni, L. Bianchi, K. Hansel, D. Neve, C. Foti, M. Corazza, V. Bini, I. Moretta, M. Principato
    Journal of the European Academy of Dermatology and Venereology.2017; 31(9): 1526.     CrossRef
  • 17,753 View
  • 99 Download
  • 8 Web of Science
  • Crossref

Brief Communication

Cryptosporidium hominis Infection Diagnosed by Real-Time PCR-RFLP
Hyeng-Il Cheun, Kyungjin Kim, Sejoung Yoon, Won-Ja Lee, Woo-Yoon Park, Seobo Sim, Jae-Ran Yu
Korean J Parasitol 2013;51(3):353-355.
Published online June 30, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.3.353

There are approximately 20 known species of the genus Cryptosporidium, and among these, 8 infect immunocompetent or immunocompromised humans. C. hominis and C. parvum most commonly infect humans. Differentiating between them is important for evaluating potential sources of infection. We report here the development of a simple and accurate real-time PCR-based restriction fragment length polymorphism (RFLP) method to distinguish between C. parvum and C. hominis. Using the CP2 gene as the target, we found that both Cryptosporidium species yielded 224 bp products. In the subsequent RFLP method using TaqI, 2 bands (99 and 125 bp) specific to C. hominis were detected. Using this method, we detected C. hominis infection in 1 of 21 patients with diarrhea, suggesting that this method could facilitate the detection of C. hominis infections.

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  • Causes of acute gastroenteritis in Korean children between 2004 and 2019
    Eell Ryoo
    Clinical and Experimental Pediatrics.2021; 64(6): 260.     CrossRef
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    Jennifer K. O'Leary, Roy D. Sleator, Brigid Lucey
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  • Comparison of Three Real-Time PCR Assays Targeting the SSU rRNA Gene, the COWP Gene and the DnaJ-Like Protein Gene for the Diagnosis of Cryptosporidium spp. in Stool Samples
    Felix Weinreich, Andreas Hahn, Kirsten Alexandra Eberhardt, Torsten Feldt, Fred Stephen Sarfo, Veronica Di Cristanziano, Hagen Frickmann, Ulrike Loderstädt
    Pathogens.2021; 10(9): 1131.     CrossRef
  • Lateral Flow Loop-Mediated Isothermal Amplification Test with Stem Primers: Detection ofCryptosporidiumSpecies in Kenyan Children Presenting with Diarrhea
    Timothy S. Mamba, Cecilia K. Mbae, Johnson Kinyua, Erastus Mulinge, Gitonga Nkanata Mburugu, Zablon K. Njiru
    Journal of Tropical Medicine.2018; 2018: 1.     CrossRef
  • Expression and Purification of gp40/15 Antigen of Cryptosporidium parvum Parasite in Escherichia coli: an Innovative Approach in Vaccine Production
    Hossein Sobati, Habib Jasor-Gharebagh, Hossein Honari
    Iranian Red Crescent Medical Journal.2017;[Epub]     CrossRef
  • Detection of Cryptosporidium parvum in Environmental Soil and Vegetables
    Semie Hong, Kyungjin Kim, Sejoung Yoon, Woo-Yoon Park, Seobo Sim, Jae-Ran Yu
    Journal of Korean Medical Science.2014; 29(10): 1367.     CrossRef
  • 10,258 View
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Original Article

Monthly Occurrence of Vectors and Reservoir Rodents of Scrub Typhus in an Endemic Area of Jeollanam-do, Korea
Seung Hyun Lee, Young-Sun Lee, In Yong Lee, Jae Won Lim, Hee-Kwan Shin, Jae-Ran Yu, Seobo Sim
Korean J Parasitol 2012;50(4):327-331.
Published online November 26, 2012
DOI: https://doi.org/10.3347/kjp.2012.50.4.327

Monthly surveys were conducted to investigate the occurrence of chigger mites and seroprevalence of scrub typhus among small mammals in Jeollanam-do, the southwestern part of Korea, from November 2006 through October 2007. Fifty-eight small mammals, including 57 Apodemus agrarius (98.3%) and 1 Crocidura lasiura (1.7%), were captured, and a total of 4,675 chigger mites representing 4 genera and 8 species were collected from them. The chigger infestation rate among small mammals was 69.0%. The most predominant species in A. agrarius was Leptotrombidium scutellare (54.0%), followed by Leptotrombidium pallidum (39.4%), Leptotrombidium orientale (4.4%), Leptotrombidium palpale (1.1%), Neotrombicula tamiyai (0.6%), Eushoengastia koreaensis (0.3%), Neotrombicula gardellai (0.3%), and Cheladonta ikaoensis (<0.1%). The chigger index of A. agrarius was the highest in October (740.0), followed by November (242.0), September (134.6), March (98.3), February (38.2), January (35.3), December (34.5), April (30.8), and May (1.7). The average antibody positive rate of scrub typhus in wild rodents was 50.0%. The seropositive rates were high in October (100.0%) and November (83.3%), whereas those in other months were relatively low (28.6-57.1%). The chigger index of L. scutellare rapidly increased in September to form an acuminate peak in October, followed by a gradual decline. These results suggest that the outbreak of scrub typhus in the southwestern part of Korean peninsula is mostly due to L. scutellare.

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  • Seasonal dynamics and niches of three vector chigger species at a focus of scrub typhus in southwest China
    Yan Lv, Peng-Wu Yin, Xian-Guo Guo, Rong Fan, Cheng-Fu Zhao, Zhi-Wei Zhang, Ya-Fei Zhao, Lei Zhang
    Frontiers in Veterinary Science.2025;[Epub]     CrossRef
  • Associations of meteorological factors and dynamics of scrub typhus incidence in South Korea: A nationwide time-series study
    Taehee Chang, Kyung-Duk Min, Sung-il Cho, Yoonhee Kim
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  • Epidemiologic changes of a longitudinal surveillance study spanning 51 years of scrub typhus in mainland China
    Pei-Ying Peng, Hui-Ying Duan, Lei Xu, Lin-Tao Zhang, Ji-Qin Sun, Ya Zu, Li-Juan Ma, Yan Sun, Ting-Liang Yan, Xian-Guo Guo
    Scientific Reports.2024;[Epub]     CrossRef
  • A cross sectional study on molecular prevalence of Orientia tsutsugamushi in household rat population of South India
    S. Purushothaman, P. Azhahianambi, M. Dharman, R. Gokula Kannan, K.G. Tirumurugaan, C. Soundararajan, R.P. Aravindh Babu, Panneer Devaraju, John A.J. Prakash
    Comparative Immunology, Microbiology and Infectious Diseases.2024; 111: 102212.     CrossRef
  • Rickettsial infections: prevalence and diagnosis of scrub typhus in India
    Vigneshwaran Ravishankar, Shridhar Narayanan, Radha Krishan Shandil
    Frontiers in Tropical Diseases.2024;[Epub]     CrossRef
  • Serological Detection and Epidemiological Factors Associated with Scrub Typhus among Undifferentiated Febrile Illness Patients in a Tertiary Care Hospital
    V.M. Somasunder, K. Akila, S. Sijimol, S. Senthamarai, S. Sivasankari, C. Anitha, V.J. Subha
    Journal of Pure and Applied Microbiology.2021; 15(3): 1442.     CrossRef
  • Geographical Distribution and Epidemiologic Factors of Chigger Mites on Apodemus agrarius during Autumn in Korea
    In Yong Lee, Jae-Won Lim, Jang Hoon Seo, Heung Chul Kim, Ku Jae Lee, Tai-Soon Yong, Won-Ja Lee, Jae-Ran Yu, Seobo Sim
    The Korean Journal of Parasitology.2021; 59(5): 473.     CrossRef
  • Epidemiological Characteristics of Rodents and Chiggers with Orientia Tsutsugamushi in the Republic of Korea
    Jung Wook Park, Dae Sung Yu, Gi Seong Lee, Jin Jong Seo, Jae Keun Chung, Jae Il Lee
    The Korean Journal of Parasitology.2020; 58(5): 559.     CrossRef
  • Risk factors for acquisition of scrub typhus in children admitted to a tertiary centre and its surrounding districts in South India: a case control study
    Winsley Rose, Gagandeep Kang, Valsan Philip Verghese, Sadanandane Candassamy, Prasanna Samuel, John Jude Antony Prakash, Jayaprakash Muliyil
    BMC Infectious Diseases.2019;[Epub]     CrossRef
  • Occurrence rates of wild rodent hosts and chigger mites and the infection rate ofOrientia tsutsugamushiin the central region of South Korea from 2015 to 2018
    Moon Bo Choi, Yeongbu Kim, Da Young Kim, Ohseok Kwon
    Entomological Research.2019; 49(8): 374.     CrossRef
  • Scrub typhus ecology: a systematic review of Orientia in vectors and hosts
    Ivo Elliott, Isabelle Pearson, Prabin Dahal, Nigel V. Thomas, Tamalee Roberts, Paul N. Newton
    Parasites & Vectors.2019;[Epub]     CrossRef
  • Annual Fluctuation in Chigger Mite Populations and <italic>Orientia Tsutsugamushi</italic> Infections in Scrub Typhus Endemic Regions of South Korea
    Seong Yoon Kim, Byoungchul Gill, Bong Gu Song, Hyuk Chu, Won Il Park, Hee Il Lee, E-hyun Shin, Shin-Hyeong Cho, Jong Yul Roh
    Osong Public Health and Research Perspectives.2019; 10(6): 351.     CrossRef
  • Identification and Characterization of Orientia chuto in Trombiculid Chigger Mites Collected from Wild Rodents in Kenya
    Clement Masakhwe, Piyada Linsuwanon, Gathii Kimita, Beth Mutai, Surachai Leepitakrat, Santos Yalwala, David Abuom, Nutthanun Auysawasi, Tom Gilbreath, Elizabeth Wanja, John Waitumbi, Erik Munson
    Journal of Clinical Microbiology.2018;[Epub]     CrossRef
  • A Study on the Public Health Disasters using Meteorological Factor: Scrub Typhus in South Korea
    Younggon Lee, Kyuhyun Choi, Jaewon Kwak
    Journal of the Korean Society of Hazard Mitigation.2018; 18(3): 343.     CrossRef
  • RETROSPECTIVE ANALYSIS OF THE EPIDEMIOLOGIC LITERATURE, 1990–2015, ON WILDLIFE-ASSOCIATED DISEASES FROM THE REPUBLIC OF KOREA
    Jusun Hwang, Kyunglee Lee, Young-Jun Kim, Jonathan M. Sleeman, Hang Lee
    Journal of Wildlife Diseases.2017; 53(1): 5.     CrossRef
  • Prevalence and Phylogenetic Analysis ofOrientia tsutsugamushiin Rodents and Mites from Central India
    Ruchi Bhate, Nilesh Pansare, Sandeep P. Chaudhari, Sukhadeo B. Barbuddhe, Vijay K. Choudhary, Nitin V. Kurkure, Sunil W. Kolte
    Vector-Borne and Zoonotic Diseases.2017; 17(11): 749.     CrossRef
  • Geographical Distribution and Seasonal Indices of Chigger Mites on Small Mammals Collected on the East Coast of the Republic of Korea
    Gab-Man Park, Ho-Sung Shin
    Journal of Parasitology.2016; 102(2): 193.     CrossRef
  • Seroepidemiological Survey of Zoonotic Diseases in Small Mammals with PCR Detection of Orientia tsutsugamushi in Chiggers, Gwangju, Korea
    Jung Wook Park, Jae Keun Chung, Sun Hee Kim, Sun Ju Cho, Yi Deun Ha, So Hyang Jung, Hye Jung Park, Hyun Jae Song, Jung Yoon Lee, Dong Min Kim, Jah Pyus, Dong Ryong Ha, Eun Sun Kim, Jae Il Lee
    The Korean Journal of Parasitology.2016; 54(3): 307.     CrossRef
  • Scrub Typhus Incidence Modeling with Meteorological Factors in South Korea
    Jaewon Kwak, Soojun Kim, Gilho Kim, Vijay Singh, Seungjin Hong, Hung Kim
    International Journal of Environmental Research and Public Health.2015; 12(7): 7254.     CrossRef
  • Larval Chigger Mites Collected from Small Mammals in 3 Provinces, Korea
    In-Yong Lee, Hyeon-Je Song, Yeon-Joo Choi, Sun-Hye Shin, Min-Kyung Choi, So-Hyun Kwon, E-Hyun Shin, Chan Park, Heung-Chul Kim, Terry A. Klein, Kyung-Hee Park, Won-Jong Jang
    The Korean Journal of Parasitology.2014; 52(2): 225.     CrossRef
  • Epidemiology of Scrub Typhus and the Eschars Patterns in South Korea from 2008 to 2012
    Ji-Hyuk Park, Sun-Ja Kim, Seung-Ki Youn, Kisoo Park, Jin Gwack
    Japanese Journal of Infectious Diseases.2014; 67(6): 458.     CrossRef
  • Coincidence between Geographical Distribution of Leptotrombidium scutellare and Scrub Typhus Incidence in South Korea
    Jong Yul Roh, Bong Gu Song, Won Il Park, Eun Hee Shin, Chan Park, Mi-Yeoun Park, Kyu Sik Chang, Wook Gyo Lee, Hee Il Lee, E-Hyun Shin, Xue-jie Yu
    PLoS ONE.2014; 9(12): e113193.     CrossRef
  • A Case Series of Possibly Recrudescent Orientia tsutsugamushi Infection Presenting as Pneumonia
    Jae-Hyoung Im, Ji Hyeon Baek, Jin-Soo Lee, Moon-Hyun Chung, Sun Myoung Lee, Jae-Seung Kang
    Japanese Journal of Infectious Diseases.2014; 67(2): 122.     CrossRef
  • Are There Spatial and Temporal Correlations in the Incidence Distribution of Scrub Typhus in Korea?
    Maengseok Noh, Youngjo Lee, Chaeshin Chu, Jin Gwack, Seung-Ki Youn, Sun Huh
    Osong Public Health and Research Perspectives.2013; 4(1): 39.     CrossRef
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Brief Communication

Risk Factors Associated with Head Louse Infestation in Korea
Seobo Sim, Won-Ja Lee, Jae-Ran Yu, In Yong Lee, Seung Hyun Lee, Soo-Youn Oh, Min Seo, Jong-Yil Chai
Korean J Parasitol 2011;49(1):95-98.
Published online March 18, 2011
DOI: https://doi.org/10.3347/kjp.2011.49.1.95

Head louse infestation (HLI) is one of the most frequently occurring parasitic diseases in children. This study was conducted to investigate the socioeconomic and personal factors influencing HLI in the Republic of Korea. A total of 2,210 questionnaires about various factors related to HLI were obtained from children in 17 primary schools throughout the country. The rate of HLI was significantly lower in children who lived together with mother or in a family where both parents worked. In addition, HLI was lower in children whose fathers or mothers were public officers or teachers. However, HLI was higher in children who had small families and washed their hair less often. Education levels of parents and the number of children in family were not significant. Improvement of socioeconomic factors and personal hygiene will be helpful for reducing HLI.

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    Zuhair Dardona, Mounia Amane, Samia Boussaa
    Egyptian Journal of Dermatology and Venereology.2025; 45(2): 127.     CrossRef
  • Monitoring the impact, trends, and impact levels of factors affecting Pediculus capitis infestation in primary school students: An illustrative scale of evidence review
    Hassan Nasirian
    Journal of Public Health.2024; 32(8): 1479.     CrossRef
  • Epidemiological analysis of pediculosis and the distribution of kdr mutation frequency in head lice populations in Torbat Heydarieh city of Khorasan Razavi Province, Northeastern Iran
    Mohammad Taheri, Fereshteh Ghahvechi Khaligh, Ahmad Ali Hanafi-Bojd, Hamid Reza Khalkhali, Kamal Dashti, Mehdi Badakhshan, Saber Gholizadeh
    BMC Research Notes.2024;[Epub]     CrossRef
  • Prevalence of head louse infestation among primary schoolchildren in the Republic of Korea: nationwide observation of trends in 2011-2019
    Seungwan Ryoo, Sooji Hong, Taehee Chang, Hyejoo Shin, Jae Young Park, Jeonggyu Lee, Eun-Hee Nah, Eun Hee Lee, Bong-Kwang Jung, Jong-Yil Chai
    Parasites, Hosts and Diseases.2023; 61(1): 53.     CrossRef
  • Pediculosis capitis among school-age students worldwide as an emerging public health concern: a systematic review and meta-analysis of past five decades
    Kareem Hatam-Nahavandi, Ehsan Ahmadpour, Fariba Pashazadeh, Asiyeh Dezhkam, Mehdi Zarean, Raheleh Rafiei-Sefiddashti, Alireza Salimi-Khorashad, Saeed Hosseini-Teshnizi, Teimour Hazratian, Domenico Otranto
    Parasitology Research.2020; 119(10): 3125.     CrossRef
  • Social Determinants of Health, the Family, and Children’s Personal Hygiene: A Comparative Study
    Antonio Jesús Ramos-Morcillo, Francisco José Moreno-Martínez, Ana María Hernández Susarte, César Hueso-Montoro, María Ruzafa-Martínez
    International Journal of Environmental Research and Public Health.2019; 16(23): 4713.     CrossRef
  • Effect of a health education program on reduction of pediculosis in school girls at Amphoe Muang, Khon Kaen Province, Thailand
    Manachai Yingklang, Chatchawan Sengthong, Ornuma Haonon, Rungtiwa Dangtakot, Porntip Pinlaor, Chulaporn Sota, Somchai Pinlaor, David Joseph Diemert
    PLOS ONE.2018; 13(6): e0198599.     CrossRef
  • Effect of Educational Intervention Based on Protection Motivation Theory on Promoting Pediculosis Preventive Behaviors among Elementary School Girls in Neyshabur
    Masoomeh Jahani eftekhari, Nooshin Peyman
    Journal of Education and Community Health.2018; 5(2): 1.     CrossRef
  • Prevalence of head lice infestation and pediculicidal effect of permethrine shampoo in primary school girls in a low-income area in southeast of Iran
    Moussa Soleimani-Ahmadi, Seyed Aghil Jaberhashemi, Mehdi Zare, Alireza Sanei-Dehkordi
    BMC Dermatology.2017;[Epub]     CrossRef
  • Assessment of the Prevalence of Pediculosis capitis among Primary School Girls in Riyadh, Saudi Arabia
    Wafa A.I. AL-Me
    Research Journal of Environmental Sciences.2015; 9(4): 193.     CrossRef
  • Prevalence of Head Lice Infestation and Its Associated Factors among Primary School Students in Iran: A Systematic Review and Meta-analysis
    Mahmood Moosazadeh, Mahdi Afshari, Hormoz Keianian, Asghar Nezammahalleh, Ahmad Ali Enayati
    Osong Public Health and Research Perspectives.2015; 6(6): 346.     CrossRef
  • Reemerging skin disease caused by arthropods II: louse
    Seobo Sim, Ki-Soo Pai
    Journal of the Korean Medical Association.2011; 54(5): 523.     CrossRef
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Original Articles

Involvement of Src Family Tyrosine Kinase in Apoptosis of Human Neutrophils Induced by Protozoan Parasite Entamoeba histolytica
Seobo Sim, Jae-Ran Yu, Young Ah Lee, Myeong Heon Shin
Korean J Parasitol 2010;48(4):285-290.
Published online December 16, 2010
DOI: https://doi.org/10.3347/kjp.2010.48.4.285

Tyrosine kinases are one of the most important regulators for intracellular signal transduction related to inflammatory responses. However, there are no reports describing the effects of tyrosine kinases on neutrophil apoptosis induced by Entamoeba histolytica. In this study, isolated human neutrophils from peripheral blood were incubated with live trophozoites in the presence or absence of tyrosine kinase inhibitors. Entamoeba-induced receptor shedding of CD16 and PS externalization in neutrophils were inhibited by pre-incubation of neutrophils with the broad-spectrum tyrosine kinase inhibitor genistein or the Src family kinase inhibitor PP2. Entamoeba-induced ROS production was also inhibited by genistein or PP2. Moreover, genistein and PP2 blocked the phosphorylation of ERK and p38 MAPK in neutrophils induced by E. histolytica. These results suggest that Src tyrosine kinases may participate in the signaling event for ROS-dependent activation of MAPKs during neutrophil apoptosis induced by E. histolytica.

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  • The Src family kinases contribute to MII arrest maintenance in aging porcine oocytes
    Kateřina Kheilová, Jaroslav Petr, Dalibor Řehák, Eva Chmelíková, Markéta Sedmíková
    Theriogenology.2025; 248: 117614.     CrossRef
  • The flip side of reactive oxygen species in the tropical disease‐Amoebiasis
    Sakshi Desure, Arya Mallika, Mrinalini Roy, Anupam Jyoti, Sanket Kaushik, Vijay Kumar Srivastava
    Chemical Biology & Drug Design.2021; 98(5): 930.     CrossRef
  • Differential expression of ADAM15 and ADAM17 metalloproteases in the rat brain after severe hypobaric hypoxia and hypoxic preconditioning
    Elena Rybnikova, Tatjana Gluschenko, Anasthasia Galeeva, Ekaterina Tulkova, Natalia N. Nalivaeva, Natalia Z. Makova, Anthony J. Turner, Mikhail Samoilov
    Neuroscience Research.2012; 72(4): 364.     CrossRef
  • 8,413 View
  • 64 Download
  • Crossref
Microphallus koreana n. sp. (Trematoda: Microphallidae) Transmitted by a Marine Crab, Macrophthalmus dilatatus
Sang-Mee Guk, Jong-Yil Chai, Woon-Mok Sohn, You-Me Kim, Seobo Sim, Min Seo
Korean J Parasitol 2008;46(3):165-169.
Published online September 20, 2008
DOI: https://doi.org/10.3347/kjp.2008.46.3.165

Microphallus species occur primarily as intestinal parasites of birds and mammals, and metacercariae of a new species belonging to this genus have been discovered from the crab, Macrophthalmus dilatatus, in the Republic of Korea. The metacercaria of this fluke was round with 2 thick walls, and the excysted one had mature genital organs. The adult flukes recovered from experimentally infected chicks had numerous intrauterine eggs, well-developed pars prostatica, widely bifurcating ceca, and prominent uterine bulge. After observing internal structures, it was concluded that this species is different from any other known Microphallus spp. Based on the morphology of metacercariae and adult flukes, we describe this specimen as a new species, Microphallus koreana n. sp.

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    International Journal of Biosciences (IJB).2020; : 464.     CrossRef
  • Infections with Digenetic Trematode Metacercariae in Freshwater Fishes from Two Visiting Sites of Migratory Birds in Gyeongsangnam-do, Republic of Korea
    Woon-Mok Sohn, Byoung-Kuk Na
    The Korean Journal of Parasitology.2019; 57(3): 273.     CrossRef
  • Morphology and histology of the adultParamphistomum gracileFischoeder, 1901
    Busaba Panyarachun, Arin Ngamniyom, Prasert Sobhon, Panat Anuracpreeda
    Journal of Veterinary Science.2013; 14(4): 425.     CrossRef
  • Discovery ofMaritrema obstipum(Digenea: Microphallidae) from Migratory Birds in Korea
    Ok-Sik Chung, Woon-Mok Sohn, Jong-Yil Chai, Min Seo, Hye-Jung Lee
    The Korean Journal of Parasitology.2011; 49(4): 457.     CrossRef
  • Surveys of Gynaecotyla squatarolae and Microphallus koreana (Digenea: Microphallidae) Metacercariae in Two Species of Estuarine Crabs in Western Coastal Areas, Korea
    Hye Jung Lee, Jong-Yil Chai, Jin-Woo Lee, Ho Jin, Kwan-Hong Min, Yong-Jun Cho, Min Seo
    The Korean Journal of Parasitology.2010; 48(1): 81.     CrossRef
  • Discovery ofMaritrema jebuensisn. sp. (Digenea: Microphallidae) from the Asian Shore Crab,Hemigrapsus sanguineus, in Korea
    Ok-Sik Chung, Hye-Jung Lee, Woon-Mok Sohn, Seung-Ha Lee, Il-Yong Park, Sang-Ah Oh, Jong-Yil Chai, Min Seo
    The Korean Journal of Parasitology.2010; 48(4): 335.     CrossRef
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Holostephanus metorchis (Digenea: Cyathocotylidae) from Chicks Experimentally Infected with Metacercariae from a Fish, Pseudorasbora parva, in the Republic of Korea
Min Seo, Sang-Mee Guk, Jong-Yil Chai, Seobo Sim, Woon-Mok Sohn
Korean J Parasitol 2008;46(2):83-86.
Published online June 20, 2008
DOI: https://doi.org/10.3347/kjp.2008.46.2.83

Holostephanus metorchis(Digenea: Cyathocotylidae) is a parasite of birds, transmitted by freshwater fishes. H. metorchis adults were recovered from chicks experimentally infected with metacercariae collected from freshwater fishes, Pseudorasbora parva. The metacercariae were oval, surrounded with thick fibrous capsules. In adult flukes, the holdfast organ occupied the ventral concavity, and the anterior testis did not reach the level of the ventral sucker. Based on these morphological characteristics, these flukes were identified as H. metorchis.

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    Feng Jiang, Wanyu Zhang, Yang Pan, Xudong Yu, Jiacheng Cao, Ningning Du, Mengyi Zhu, Shengli Gu, Xiaodong Zhan
    Veterinary Research Communications.2023; 47(3): 1185.     CrossRef
  • Digenean Holostephanus (Trematoda: Digenea: Cyathocotylidae) metacercariae in common carp (Cyprinus carpio Linnaeus, 1758) muscle: zoonotic potential and sensitivity to physico-chemical treatments
    D. Sándor, M. Gyöngy, K. Nyeste, I. Czeglédi, C. Székely, K. Buchmann, G. Cech
    Journal of Helminthology.2020;[Epub]     CrossRef
  • Infections of Digenetic Trematode Metacercariae in Wrestling Halfbeak, Dermogenys pusilla from Bangkok Metropolitan Region in Thailand
    Laddawan Patarwut, Thapana Chontananarth, Jong-Yil Chai, Watchariya Purivirojkul
    The Korean Journal of Parasitology.2020; 58(1): 27.     CrossRef
  • Pan‐continental invasion ofPseudorasbora parva: towards a better understanding of freshwater fish invasions
    Rodolphe E Gozlan, Demetra Andreou, Takashi Asaeda, Kathleen Beyer, Rachid Bouhadad, Dean Burnard, Nuno Caiola, Predrag Cakic, Vesna Djikanovic, Hamid R Esmaeili, Istvan Falka, Duncan Golicher, Akos Harka, Galina Jeney, Vladimír Kováč, Jiří Musil, Annamar
    Fish and Fisheries.2010; 11(4): 315.     CrossRef
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Brief Communications

Differential diagnosis of Trichostrongylus and hookworm eggs via PCR using ITS-1 sequence
Tai-Soon Yong, Jong-Ho Lee, Seobo Sim, Jongweon Lee, Duk-Young Min, Jong-Yil Chai, Keeseon S. Eom, Woon-Mok Sohn, Soon-Hyung Lee, Han-Jong Rim
Korean J Parasitol 2007;45(1):69-74.
Published online March 20, 2007
DOI: https://doi.org/10.3347/kjp.2007.45.1.69

Trichostrongylus eggs observed in cellophane-thick smears are difficult, in practice, to distinguish from hookworm eggs. In order to overcome these limitations, a molecular approach was conducted. A Trichostrongylus colubriformis adult worm was obtained from a human in Laos, which was identified morphologically. ITS-1 sequence of this worm was determined, and found to be most similar with that of T. colubriformis among the Trichostrongylus spp. reported so far. Then, this sequence was compared with those of human hookworm species, Ancylostoma duodenale and Necator americanus, and species-specific oligonucleotide primers were designed. Polymerase chain reaction (PCR) using these primers evidenced specifically amplified PCR products of Trichostrongylus sp., A. duodenale and N. americanus from the eggs of each (520 bp, 690 bp, and 870 bp, respectively). A species-specific PCR technique can be developed in order to study the epidemiology of Trichostrongylus spp. and hookworms in endemic areas.

Citations

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  • Molecular Characterization and Analysis of Human Trichostrongylus Species in an Endemic Region of Iran Based on COX 1 Gene; A Cross‐Sectional Study
    Sara Nemati, Hanieh Mohammad Rahimi, Meysam Sharifdini, Hamed Mirjalali
    Health Science Reports.2025;[Epub]     CrossRef
  • Trichostrongylosis: a zoonotic disease of small ruminants
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Ultrastructural observation of human neutrophils during apoptotic cell death triggered by Entamoeba histolytica
Seobo Sim, Kyeong Ah Kim, Tai-Soon Yong, Soon-Jung Park, Kyung-il Im, Myeong Heon Shin
Korean J Parasitol 2004;42(4):205-208.
Published online December 20, 2004
DOI: https://doi.org/10.3347/kjp.2004.42.4.205

Neutrophils are important effector cells against protozoan extracellular parasite Entamoeba histolytica, which causes amoebic colitis and liver abscess in human beings. Apoptotic cell death of neutrophils is an important event in the resolution of inflammation and parasite's survival in vivo. This study was undertaken to investigate the ultrastructural aspects of apoptotic cells during neutrophil death triggered by Entamoeba histolytica. Isolated human neutrophils from the peripheral blood were incubated with or without live trophozoites of E. histolytica and examined by transmission electron microscopy (TEM). Neutrophils incubated with E. histolytica were observed to show apoptotic characteristics, such as compaction of the nuclear chromatin and swelling of the nuclear envelop. In contrast, neutrophils incubated in the absence of the amoeba had many protrusions of irregular cell surfaces and heterogenous nuclear chromatin. Therefore, it is suggested that Entamoeba-induced neutrophil apoptosis contribute to prevent unwanted tissue inflammation and damage in the amoeba-invaded lesions in vivo.

Citations

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Original Article

A survey on head lice infestation in Korea (2001) and the therapeutic efficacy of oral trimethoprim/sulfamethoxazole adding to lindane shampoo
Seobo Sim, In-Yong Lee, Kyu-Jae Lee, Jang-Hoon Seo, Kyung-Il Im, Myeong Heon Shin, Tai-Soon Yong
Korean J Parasitol 2003;41(1):57-61.
Published online March 20, 2003
DOI: https://doi.org/10.3347/kjp.2003.41.1.57

Total of 7,495 children including 3,908 boys and 3,587 girls from a kindergarten and 15 primary schools were examined for head lice infestation (HLI). The overall prevalence of HLI in this study was found to be 5.8%. Head lice were much more commonly detected in girls than in boys with prevalence of 11.2% and 0.9%, respectively. Sixty-nine children with HLI were treated with 1% lindane shampoo alone (group 1), and 45 children with HLI were treated with 1% lindane shampoo and oral trimethoprim/sulfamethoxazole (group 2), and follow-up visits were conducted 2 and 4 weeks later. The children who still had HLI 2 weeks after the primary treatment were treated again. At the 2-week follow-up visit, the treatment success rates of groups 1 and 2 were 76.8% and 86.7%, respectively, and at the 4-week follow-up visit, the rates were 91.3% and 97.8%, respectively. No statistically significant synergistic effect was observed for the combination of a 1% lindane shampoo and oral trimethoprim/sulfamethoxazole.

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Case Report

A case of breast sparganosis
Seobo Sim, Jai-Kyung You, In-Yong Lee, Kyung-Il Im, Tai-Soon Yong
Korean J Parasitol 2002;40(4):187-189.
Published online December 30, 2002
DOI: https://doi.org/10.3347/kjp.2002.40.4.187

A 29-year-old Korean woman visited the Department of Surgery in MizMedi Hospital with a palpable itching mass on the right breast that had existed for the past 7 months. She had no history to eat either frogs or snakes, but had the history of drinking impure water. Sonography revealed a serpiginous hypoechoic tubular structure associated with partial fat necrosis in breast parenchymal layer and subcutaneous fat layer. It also revealed oval cystic lesions. At operation, an ivory white opaque ribbon-like worm that measured 16.5 cm in length and 0.5 cm in width was extracted. Anti-sparganum specific serum IgG level in the patient's serum (absorbance = 0.71), measured by ELISA, was found to be significantly higher than those of normal controls (cut off point = 0.21). Sonography and ELISA appear to be helpful to diagnose sparganosis. Breast sparganosis is rarely found throughout the world.

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Brief Communication
A small-scale survey on the status of intestinal parasite infections in rural villages in Nepal
Tai-Soon Yong, Seobo Sim, Jongweon Lee, Heechoul Ohrr, Myung-Ho Kim, Hyunsoo Kim
Korean J Parasitol 2000;38(4):275-277.
Published online December 31, 2000
DOI: https://doi.org/10.3347/kjp.2000.38.4.275

The status of intestinal parasite infections was investigated in two rural villages (Chitrasar, Jerona) in Chitwan District, Nepal in 1999. Stool examination was performed with a total of 300 specimens from schoolchildren by formalin-ether sedimentation technique. The prevalence rate of intestinal parasite infections in the surveyed areas was 44.0%. The prevalence rate in Jerona was slightly higher than that in Chitrasar. The prevalence rate of intestinal parasite infections in female was slighly higher than that in male without statistically significant difference. Entamoeba coli was the most commonly found protozoan parasite (21.0%) followed by Giardia lamblia (13.7%) and others (5.3%). Hookworm was the most prevalent intestinal helminth (13.0%) followed by Trichuris trichiura (3.0%) and others (5.0%). Forty-three specimens (14.3%) showed mixed infections. It is necessary to implement large-scale treatment with anthelminthics, health education and sanitary improvement for intestinal parasite control in the surveyed areas.

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