Parasites, Hosts and Diseases

"Toxocara cati"

Brief Communications

A Seroepidemiological Survey of Toxocariasis among Eosinophilia Patients in Chungcheongnam-do: Min Seo, Sung Chul Yoon; Korean J Parasitol 2012;50(3):249-251.
Published online August 13, 2012; DOI: https://doi.org/10.3347/kjp.2012.50.3.249

Abstract
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There have been several reports on the relationship between toxocariasis and eosinophilia, but all have been limited to the areas of Seoul or Gangwon-do. In the present study, we investigated the seroprevalence of toxocariasis among eosinophilia patients in Chungcheongnam-do, the central district of Korea. Among the 101 patients tested, 51 (50.5%) were identified as positive by Toxocara ELISA, and 46 (45.5%) were confidently diagnosed with toxocariasis because of absence of any other cause of eosinophilia. Whereas 22 of 42 seropositive patients (52.3%) had a recent history of consuming raw livers, especially the cow liver, only 1 of 25 seronegative patients (4%) had done so (P<0.01). From these results, we could confirm that toxocariasis is related to eosinophilia, and infer that ingestion of raw cow liver plays a vital role in the transmission of toxocariasis in Chungcheongnam-do.

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Experimental Toxocara cati Infection in Gerbils and Rats: Mohammad Zibaei, Seyed Mahmoud Sadjjadi, Shoji Uga; Korean J Parasitol 2010;48(4):331-333.
Published online December 16, 2010; DOI: https://doi.org/10.3347/kjp.2010.48.4.331

Abstract
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Mongolian gerbils and Wistar rats were inoculated orally with 240 and 2,500 Toxocara cati embryonated eggs, respectively, to evaluate the larval recovery in different tissues and organs, such as the liver, lungs, heart, kidney, and skeletal muscles after 5, 30, 49, 70, and 92 days post-infection (PI). Larval recovery rates were 1.7-30.0% in Mongolian gerbils on days 5-92 PI and 0.2-3.8% in rats on the same days. These results indicate that Mongolian gerbils and Wistar rats are suitable experimental paratenic hosts for the study of neurological toxocariasis as well as visceral toxocariasis.

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Zahra Shayesteh, Hamid Hosseini, Vahid Nasiri, Zeinab Haddadi, Najmeh Moradi, Leila Beikzadeh, Monireh Sezavar, Aliehsan Heidari, Mohammad Zibaei
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Experimental Parasitology.2014; 144: 73. CrossRef
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Bahador Sarkari, Malihe Lari, Reza Shafiei, Seyed Mahmoud Sadjjadi
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Elisabeth Janecek, Andreas Beineke, Thomas Schnieder, Christina Strube
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Mohammad Zibaei, Seyed Mahmoud Sadjjadi, Mehdi Karamian, Shoji Uga, Ahmad Oryan, Seyed Hamidreza Jahadi-Hosseini
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9,052 View
96 Download
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Longevity of Toxocara cati Larvae and Pathology in Tissues of Experimentally Infected Chickens: Oryan, Ahmad , Sadjjadi, Seyyed Mahmoud , Azizi, Shahrzad; Korean J Parasitol 2010;48(1):79-80.; DOI: https://doi.org/10.3347/kjp.2010.48.1.79

Abstract
PDF

This study was conducted to determine the distribution patterns and duration of stay of Toxocara cati larvae in organs of chickens and to investigate chronic phase and potential zoonotic risk of toxocariasis in chickens. Chickens were orally infected with 1,000 embryonated T. cati eggs and necropsied 240 days post-infection. Organs of the chickens were examined at gross and microscopic levels; tissues were digested to recover larvae. Peribronchiolitis with infiltration of lymphocytes, and hyperplasia of bronchiolar associated lymphatic tissues (BALT) and goblet cells, were evident in the lungs of infected chickens. There were mild hemorrhages and infiltration of lymphocytes and a few eosinophils in the meninges. Larvae were recovered from 30% of the exposed chickens. Larvae recovery indicated that T. cati larvae stay alive for at least 240 days in the chicken brain. Therefore, chickens may potentially act as a paratenic host in nature and transfer T. cati larvae to other hosts.

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