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"artesunate"

Case Reports
COVID-19 and Plasmodium ovale Malaria: A Rare Case of Co-Infection
Bilge Caglar, Ridvan Karaali, Ilker Inanc Balkan, Bilgul Mete, Gokhan Aygun
Korean J Parasito 2021;59(4):399-402.
Published online August 18, 2021
DOI: https://doi.org/10.3347/kjp.2021.59.4.399
The COVID-19 pandemic continues to be a major health problem worldwide. Timely diagnosis of co-infections mimicking COVID-19, such as malaria, might be challenging particularly in non-endemic areas. We report the first case of COVID-19 and Plasmodium ovale malaria co-infection from our region aiming to highligt the importance of travel history and prophylaxis in malaria management in the context of pandemic. The galloping sound can sometimes be a harbinger of zebra besides the horse.

Citations

Citations to this article as recorded by  Crossref logo
  • Optimal control analysis of a mathematical model of malaria and COVID-19 co-infection dynamics
    Abou Bakari Diabaté, Boureima Sangaré, Ousmane Koutou
    Journal of Biological Dynamics.2025;[Epub]     CrossRef
  • Safety and Efficacy of Imatinib, Nilotinib, and Artesunate in COVID-19 Patients: A Systematic Review of Current Evidence
    Ehsan Ghavimehr, Ali Zand, Seyed Ahmad SeyedAlinaghi, Amirali Karimi, Hamid Zaferani Arani, Pegah Mirzapour, Zahra Pashaei, Esmaeil Mehraeen, Omid Dadras
    Anti-Infective Agents.2024;[Epub]     CrossRef
  • COVID-19 and malaria co-infection: a systematic review of clinical outcomes in endemic areas
    Amal H. Mohamed, Ebtihal Eltyeb, Badria Said, Raga Eltayeb, Abdullah Algaissi, Didier Hober, Abdulaziz H. Alhazmi
    PeerJ.2024; 12: e17160.     CrossRef
  • Effect of the second and third COVID-19 pandemic waves on routine outpatient malaria indicators and case management practices in Uganda: an interrupted time series analysis
    Pius Mukisa, Freddy Eric Kitutu, Arthur Mpimbaza, Jaffer Okiring, Joan N. Kalyango, Joaniter I. Nankabirwa
    Malaria Journal.2024;[Epub]     CrossRef
  • Mixed infection with COVID-19 and tropical malaria (case report)
    Dmitriy O. Efremov, Ainur R. Khuramshin, Sergey S. Кozlov, Nikolay I. Gulyaev
    Epidemiology and Infectious Diseases.2023; 28(1): 53.     CrossRef
  • Co-infection of COVID-19 and parasitic diseases: A systematic review
    Fatemeh Nemati Zargaran, Mosayeb Rostamian, Sara Kooti, Hamid Madanchi, Keyghobad Ghadiri
    Parasite Epidemiology and Control.2023; 21: e00299.     CrossRef
  • Clinical characteristics of malaria in COVID-19: A systematic review of case reports
    Chandana Rayella, Praveen Devanandan, Kavitha Rasuri, Sai Sudha Yerravelly, Sanjana Andem, Ranadheer Chowdary Puvvada
    Tropical Parasitology.2023; 13(1): 22.     CrossRef
  • MIS-C and co-infection with P. vivax and P. falciparum in a child: a clinical conundrum
    Michela Scalisi, Salvatore Giordano, Laura Antonella Canduscio, Maria Concetta Failla, Luca Messina, Elisa Sferrazza, Raffaella Rubino, Lucia Siracusa, Veronica Vanella, Antonio Cascio, Claudia Colomba
    Italian Journal of Pediatrics.2022;[Epub]     CrossRef
  • Co-Infection with Plasmodium vivax and COVID-19 in Thailand
    Parat Boonyarangka, Kittijarankon Phontham, Sabaithip Sriwichai, Kamonporn Poramathikul, Krit Harncharoenkul, Worachet Kuntawunginn, Napat Maneesrikhum, Sarayouth Srisawath, Chanida Seenuan, Chattakorn Thanyakait, Kanjana Inkabajan, Suda Pludpiem, Kingkan
    Tropical Medicine and Infectious Disease.2022; 7(8): 145.     CrossRef
  • SARS-CoV-2 and Plasmodium falciparum Co-Infection in a Returning Traveler
    Qian Huang, Wen-Jie Xu, Xiao-Xiao Wang, Xuan Zhang, Ke-Nu Pan, Jia-Qi Zhang, Hua-Liang Chen, Wei Ruan, Li-Nong Yao
    Frontiers in Public Health.2022;[Epub]     CrossRef
  • The striking mimics between COVID-19 and malaria: A review
    Emadeldin Hassan E. Konozy, Makarim El-fadil M. Osman, George Ghartey-Kwansah, Hind Mohamed Abushama
    Frontiers in Immunology.2022;[Epub]     CrossRef
  • 4,960 View
  • 136 Download
  • 9 Web of Science
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An Imported Case of Severe Falciparum Malaria with Prolonged Hemolytic Anemia Clinically Mimicking a Coinfection with Babesiosis
Young Ju Na, Jong-Yil Chai, Bong-Kwang Jung, Hyun Jung Lee, Ji Young Song, Ji Hye Je, Ji Hye Seo, Sung Hun Park, Ji Seon Choi, Min Ja Kim
Korean J Parasito 2014;52(6):667-672.
Published online December 23, 2014
DOI: https://doi.org/10.3347/kjp.2014.52.6.667

While imported falciparum malaria has been increasingly reported in recent years in Korea, clinicians have difficulties in making a clinical diagnosis as well as in having accessibility to effective anti-malarial agents. Here we describe an unusual case of imported falciparum malaria with severe hemolytic anemia lasting over 2 weeks, clinically mimicking a coinfection with babesiosis. A 48-year old Korean man was diagnosed with severe falciparum malaria in France after traveling to the Republic of Benin, West Africa. He received a 1-day course of intravenous artesunate and a 7-day course of Malarone (atovaquone/proguanil) with supportive hemodialysis. Coming back to Korea 5 days after discharge, he was readmitted due to recurrent fever, and further treated with Malarone for 3 days. Both the peripheral blood smears and PCR test were positive for Plasmodium falciparum. However, he had prolonged severe hemolytic anemia (Hb 5.6 g/dl). Therefore, 10 days after the hospitalization, Babesia was considered to be potentially coinfected. A 7-day course of Malarone and azithromycin was empirically started. He became afebrile within 3 days of this babesiosis treatment, and hemolytic anemia profiles began to improve at the completion of the treatment. He has remained stable since his discharge. Unexpectedly, the PCR assays failed to detect DNA of Babesia spp. from blood. In addition, during the retrospective review of the case, the artesunate-induced delayed hemolytic anemia was considered as an alternative cause of the unexplained hemolytic anemia.

Citations

Citations to this article as recorded by  Crossref logo
  • Imported parasitic diseases in the Republic of Korea: status and issues
    Jong-Yil Chai
    Journal of the Korean Medical Association.2025; 68(1): 52.     CrossRef
  • Current Status of Trypanosoma grosi and Babesia microti in Small Mammals in the Republic of Korea
    Hyun Jung Kim, BoGyeong Han, Hee-Il Lee, Jung-Won Ju, Hyun-Il Shin
    Animals.2024; 14(7): 989.     CrossRef
  • Imported human babesiosis in the Republic of Korea, 2019: two case reports
    Hyun Jung Kim, Min Jae Kim, Hyun-Il Shin, Jung-Won Ju, Hee-Il Lee
    Parasites, Hosts and Diseases.2023; 61(1): 72.     CrossRef
  • Babesia microti alleviates disease manifestations caused by Plasmodium berghei ANKA in murine co-infection model of complicated malaria
    Iqra Zafar, Tomoyo Taniguchi, Hanadi B. Baghdadi, Daisuke Kondoh, Mohamed Abdo Rizk, Eloiza May Galon, Shengwei Ji, Shimaa Abd El-Salam El-Sayed, Thom Do, Hang Li, Moaz M. Amer, Ma Zhuowei, Ma Yihong, Jinlin Zhou, Noboru Inoue, Xuenan Xuan
    Frontiers in Cellular and Infection Microbiology.2023;[Epub]     CrossRef
  • A conserved protein of Babesia microti elicits partial protection against Babesia and Plasmodium infection
    Yao Wang, Qianqian Zhang, Wanruo Zhang, Junhu Chen, Jianfeng Dai, Xia Zhou
    Parasites & Vectors.2023;[Epub]     CrossRef
  • Babesia microti Confers Macrophage-Based Cross-Protective Immunity Against Murine Malaria
    Artemis Efstratiou, Eloiza May S. Galon, Guanbo Wang, Kousuke Umeda, Daisuke Kondoh, Mohamad Alaa Terkawi, Aiko Kume, Mingming Liu, Aaron Edmond Ringo, Huanping Guo, Yang Gao, Seung-Hun Lee, Jixu Li, Paul Franck Adjou Moumouni, Yoshifumi Nishikawa, Hirosh
    Frontiers in Cellular and Infection Microbiology.2020;[Epub]     CrossRef
  • Two Imported Cases of Babesiosis with Complication or Co-Infection with Lyme Disease in Republic of Korea
    Hea Yoon Kwon, Jae Hyoung Im, Yun-Kyu Park, Areum Durey, Jin-Soo Lee, Ji Hyeon Baek
    The Korean Journal of Parasitology.2018; 56(6): 609.     CrossRef
  • Delayed Diagnosis of Falciparum Malaria with Acute Kidney Injury
    Iee Ho Choi, Pyoung Han Hwang, Sam Im Choi, Dae-Yeol Lee, Min Sun Kim
    Journal of Korean Medical Science.2016; 31(9): 1499.     CrossRef
  • Malaria endemicity and co-infection with tissue-dwelling parasites in Sub-Saharan Africa: a review
    Nyamongo W. Onkoba, Moses J. Chimbari, Samson Mukaratirwa
    Infectious Diseases of Poverty.2015;[Epub]     CrossRef
  • Artesunate

    Reactions Weekly.2015; 1574(1): 36.     CrossRef
  • 10,642 View
  • 107 Download
  • 9 Web of Science
  • Crossref
Peripheral gangrene in patients with severe falciparum malaria: report of 3 cases
Vipa Thanachartwet, Srivicha Krudsood, Polrat Wilairatana, Weerapong Phumratanaprapin, Udomsak Silachamroon, Sornchai Looareesuwan
Korean J Parasito 2006;44(2):139-143.
Published online June 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.2.139

Peripheral gangrene, characterized by distal ischemia of the extremities, is a rare complication in patients with falciparum malaria. Patients with this complication have generally undergone early amputation of the affected areas. In this report, we describe 3 adult Thai patients presented at the Hospital for Tropical Diseases, Bangkok, with high grade of fever ranged 6-9 days, jaundice, acute renal failure, respiratory failure, alteration of consciousness and shock. Two patients had gangrene developed at the lower extremities on day 1 of hospitalization and 1 patient had gangrene developed on day 3. Blood smears revealed hyperparasitemia with Plasmodium falciparum. These patients were diagnosed as having severe malaria with peripheral gangrene. The resolution of gangrene was successfully achieved by treatment with artesunate and conservative treatment in 2 of 3 cases.

Citations

Citations to this article as recorded by  Crossref logo
  • Symmetrical peripheral gangrene in an atypical case of Plasmodium falciparum malaria with HIV coinfection
    Bishakha Swain, Saurabh Kumar Singh, Uday Raj Singh
    Indian Journal of Medical Sciences.2023; 75: 88.     CrossRef
  • Acute Peripheral and/or Cutaneous Ischemic Syndrome
    Mittermayer B. Santiago, Adriane Paz
    JCR: Journal of Clinical Rheumatology.2021; 27(2): 73.     CrossRef
  • Disseminated intravascular coagulation presenting as symmetrical peripheral gangrene: a case report
    Vineet Jain, Khan Afreen, Jyotsana Kumari, Tanveer Mir, Bilal Wani, Romit Bhushan
    Journal of Medical Case Reports.2019;[Epub]     CrossRef
  • Symmetrical Peripheral Gangrene Complicating Vivax Malaria
    Krishnarpan Chatterjee, Chetana Sen
    Indian Journal of Vascular and Endovascular Surgery.2015; 2(4): 166.     CrossRef
  • Malaria-associated peripheral gangrene
    Deborah B. Martins, Vanda Amado, Stella Langa, Joyce Ventura, Atanasio Taela, Daniel A. DeUgarte
    Journal of Pediatric Surgery Case Reports.2014; 2(9): 417.     CrossRef
  • Plasmodium falciparumMalaria Complicated by Symmetrical Peripheral Gangrene, Bowel Ischemia, Repeated Candidemia, and Bacteraemia
    Emeline Masse, Philippe Hantson
    Case Reports in Medicine.2014; 2014: 1.     CrossRef
  • Peripheral gangrene in an 18-month-old boy withPlasmodium vivaxmalaria
    J Raghunandan, K Rajeshwari, A P Dubey, T Singh
    Paediatrics and International Child Health.2012; 32(3): 164.     CrossRef
  • 9,582 View
  • 63 Download
  • Crossref