Strongyloides stercoralis is a human intestinal parasite which may lead to complicated strongyloidiasis in immunocompromised. Here, a case of complicated strongyloidiasis in a patient with chronic lymphocytic leukemia is reported. Presence of numerous S. stercoralis larvae in feces and sputum confirmed the diagnosis of hyperinfection syndrome in this patient. Following recovery of filariform larvae from agar plate culture of the stool, the isolate was characterized for the ITS1 region of ribosomal DNA gene by nested-PCR and sequencing. Albendazole therapy did not have cure effects; and just at the beginning of taking ivermectin, the patient died. The most important clue to prevent such fatal consequences is early diagnosis and proper treatment.
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Strongyloidiasis Current Status with Emphasis in Diagnosis and Drug Research Tiago Mendes, Karen Minori, Marlene Ueta, Danilo Ciccone Miguel, Silmara Marques Allegretti Journal of Parasitology Research.2017; 2017: 1. CrossRef
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Strong-LAMP: A LAMP Assay for Strongyloides spp. Detection in Stool and Urine Samples. Towards the Diagnosis of Human Strongyloidiasis Starting from a Rodent Model Pedro Fernández-Soto, Alicia Sánchez-Hernández, Javier Gandasegui, Cristina Bajo Santos, Julio López-Abán, José María Saugar, Esperanza Rodríguez, Belén Vicente, Antonio Muro, James S McCarthy PLOS Neglected Tropical Diseases.2016; 10(7): e0004836. CrossRef
Single Donor-Derived Strongyloidiasis in Three Solid Organ Transplant Recipients: Case Series and Review of the Literature M. Le, K. Ravin, A. Hasan, H. Clauss, D.G. Muchant, J.K. Pasko, G. Cipollina, F. Abanyie, S.P. Montgomery, M. Loy, M. Ahmed, M. Mathur, B. Chokkalingam Mani, J. Mehr, A. Kotru, C. Varma, M. Maksimak, M. Schultz, G. Obradovic, R. Alvarez, Y. Toyoda, M. Bir American Journal of Transplantation.2014; 14(5): 1199. CrossRef
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Strongyloidiasis: An Emerging Infectious Disease in China Xiaohong Zhou, Anthony A. James, Chunmei Wang, Juan Li, Xiaoguang Chen, Guiyun Yan, Jiabao Xu The American Journal of Tropical Medicine and Hygiene.2013; 88(3): 420. CrossRef
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