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Original Article

Ampicillin treated German cockroach extract leads to reduced inflammation in human lung cells and a mouse model of Asthma
Seogwon Lee, Myung-Hee Yi, Yun Soo Jang, Jun Ho Choi, Myungjun Kim, Soo Lim Kim, Tai-Soon Yong, Ju Yeong Kim
Parasites Hosts Dis 2023;61(1):60-71.
Published online February 22, 2023
DOI: https://doi.org/10.3347/PHD.22147
Cockroaches can cause allergic sensitization in humans via contact with their feces or frass. Antibiotics can affect concentration of major allergen and total bacteria production in German cockroaches (Blattella germanica). This study examined the ability of antibiotic-treated German cockroaches to induce allergic airway inflammation and the effect of antibiotics on their lipopolysaccharide and Bla g1, 2, and 5 expression levels. Specifically, we measured the ability of German cockroach extract (with or without prior antibiotic exposure) to induce allergic inflammation in human bronchial epithelial cells and a mouse model of asthma. Bacterial 16S rRNA and lipopolysaccharide levels were lower in ampicillin-treated cockroaches than in the control group. The Bla g1, Bla g2, and Bla g5 expression in ampicillin-treated cockroaches decreased at both the protein and RNA levels. In human bronchial epithelial cell lines BEAS-2B exposed to the ampicillin-treated extract, expression levels of interleukin-6 and interleukin-8 were lower than that in the control group. The total cell count and eosinophil count in bronchoalveolar lavage fluid was also lower in mice exposed to the ampicillin-treated extract than in those exposed to normal cockroach extract. Mouse lung histopathology showed reduced immune cell infiltration and mucus production in the ampicillin group. Our results showed that ampicillin treatment reduced the symbiont bacterial population and major allergen levels in German cockroaches, leading to reduced airway inflammation in mice. These results can facilitate the preparation of protein extracts for immunotherapy or diagnostics applications.

Citations

Citations to this article as recorded by  Crossref logo
  • Asthma research in mice: An overview of current models and their methodological variability
    Yan-Jiao Chen, Cai-Tao Chen, Gabriel Shimizu Bassi, Yong-Qing Yang
    International Reviews of Immunology.2025; 44(3): 127.     CrossRef
  • Invasive indoor pests under the microbiological lens: bacterial and viral diversity from local to global scales in bed bugs and cockroaches
    Jose E Pietri, Maureen Laroche
    Current Opinion in Insect Science.2025; 69: 101344.     CrossRef
  • Multi-omics of cockroaches infected with Salmonella Typhimurium identifies molecular signatures of vector colonization
    Diing DM Agany, Eduardo A. Callegari, Maria D. Paez, Jose E. Pietri
    BMC Genomics.2025;[Epub]     CrossRef
  • Microbiome of laboratory‐reared and environmentally collected cockroaches
    Sohyeon Yun, Jun Ho Choi, Singeun Oh, Myungjun Kim, Myung‐hee Yi, Dongjun Kang, Yun Soo Jang, In‐Yong Lee, Tai‐Soon Yong, Juan Kim, Heung Chul Kim, Jae Rok Lee, Ju Yeong Kim
    Entomological Research.2024;[Epub]     CrossRef
  • 4,166 View
  • 163 Download
  • 3 Web of Science
  • Crossref

Brief Communication

Cockroach as a Vector of Blastocystis sp. is Risk for Golden Monkeys in Zoo
Lei Ma, Yongbin Zhang, Haixia Qiao, Shuai Li, Heqin Wang, Ningning Zhang, Xiao Zhang
Korean J Parasitol 2020;58(5):583-587.
Published online October 22, 2020
DOI: https://doi.org/10.3347/kjp.2020.58.5.583
Blastocystis sp. is a kind of protozoa living in the intestinal tract of human and animals, which will cause intestinal diseases such as diarrhea, abdominal distension and vomiting. This paper was aimed to understand the infection of Blastocystis sp. In golden monkeys and the transmission path in North China. Thirty-seven feces samples from golden monkeys and 116 cockroach samples from Shijiazhuang Zoo were collected from July to October 2019 for PCR analysis of Blastocystis sp. Genetic diversity analysis was further conducted on the samples with positive PCR results. The results showed that the infection rate was 48.7% (18/37) in golden monkeys and 82.8% (96/116) in cockroaches, respectively. The genetic evolution analysis based on small subunit ribosomal RNA demonstrated that three subtypes (ST) of Blastocystis sp. including ST1, ST2, and ST3 existed in the intestinal tract of golden monkeys, while only ST2 was detected in the intestinal tract of cockroaches. This paper may provide supports for the quarantine and control of Blastocystis sp. for the zoo in Northern China.

Citations

Citations to this article as recorded by  Crossref logo
  • The contamination of human residential environments by intestinal protozoan parasites in cockroaches: a systematic review, meta-analysis and future predictions (up to 2035)
    Milad Badri, Mohammad Ali Mohaghegh, Meysam Olfatifar, Amir Abdoli, Leila Zaki, Ali Asghari, Razagh Mahmodi, Daniel Diaz, Aida Vafae Eslahi
    International Journal of Environmental Health Research.2025; 35(11): 3604.     CrossRef
  • Molecular Detection and Genotyping of Blastocystis in Farmed Minks and Raccoon Dogs in Northern China
    Nian-Yu Xue, Yanchun Wang, Hai-Tao Wang, Qing-Yu Hou, Ya Qin, Jing Jiang, Yan Tang
    Foodborne Pathogens and Disease.2025;[Epub]     CrossRef
  • Molecular Detection and Subtype Distribution of Blastocystis sp. in Cold-water Fish and cultured water
    Yuwei Wang, Chao Zhang, Huizhu Nan, Shi Yin, Mengjuan Cao, Ruiyong An, Lei Ma
    Israeli Journal of Aquaculture - Bamidgeh.2024;[Epub]     CrossRef
  • Fatal coinfection of blastocystosis and intestinal trichomoniasis in a rhesus macaque (Macaca mulatta)
    Varun Kumar Sarkar, Ujjwal Kumar De, Pooja Solanki, Harshit Saxena, Shivansh Mehra, Devendra Prasad Pateer, Sudhir Kumar Prajapati
    Journal of Parasitic Diseases.2024; 48(2): 400.     CrossRef
  • Molecular Identification and Subtype Analysis of Blastocystis sp. Isolates from Wild Mussels (Mytilus edulis) in Northern France
    Manon Ryckman, Nausicaa Gantois, Ruben Garcia Dominguez, Jeremy Desramaut, Luen-Luen Li, Gaël Even, Christophe Audebert, Damien Paul Devos, Magali Chabé, Gabriela Certad, Sébastien Monchy, Eric Viscogliosi
    Microorganisms.2024; 12(4): 710.     CrossRef
  • Subtype–host patterns and genetic differentiation of Blastocystis sp. in the Philippines
    Davin Edric V. Adao, Windell L. Rivera
    Heliyon.2024; 10(7): e29019.     CrossRef
  • Large-Scale Molecular Epidemiological Survey of Blastocystis sp. among Herbivores in Egypt and Assessment of Potential Zoonotic Risk
    Doaa Naguib, Nausicaa Gantois, Jeremy Desramaut, Ruben Garcia Dominguez, Nagah Arafat, Samar Magdy Atwa, Gaël Even, Damien Paul Devos, Gabriela Certad, Magali Chabé, Eric Viscogliosi
    Microorganisms.2024; 12(7): 1286.     CrossRef
  • Molecular detection and public health risk assessment of Cryptosporidium spp., Giardia duodenalis, Enterocytozoon bieneusi, and Blastocystis sp. of animals in a tropical wildlife park of Hainan Island, China
    Guangxu Ren, Jiaqi Li, Jingyan Xiong, Xiuyi Lai, Yuan Wang, Sheng Lei, Xin Lu, Tianya He, Yunfei Zhou, Yun Zhang, Gang Lv
    One Health Bulletin.2023;[Epub]     CrossRef
  • A Systematic Review of Zoonotic Enteric Parasites Carried by Flies, Cockroaches, and Dung Beetles
    Avi Patel, Meg Jenkins, Kelly Rhoden, Amber N. Barnes
    Pathogens.2022; 11(1): 90.     CrossRef
  • Rare Occurrence of Blastocystis in Pet Animals and Their Owners in the Pomeranian Voivodeship in Poland in the Light of Literature Data
    Monika Rudzińska, Beata Kowalewska, Monika Kurpas, Beata Szostakowska
    Journal of Clinical Medicine.2022; 11(11): 2975.     CrossRef
  • Molecular Characterization of Blastocystis from Animals and Their Caregivers at the Gdańsk Zoo (Poland) and the Assessment of Zoonotic Transmission
    Monika Rudzińska, Beata Kowalewska, Małgorzata Waleron, Mirosław Kalicki, Katarzyna Sikorska, Beata Szostakowska
    Biology.2021; 10(10): 984.     CrossRef
  • The Coexistence of Blastocystis spp. in Humans, Animals and Environmental Sources from 2010–2021 in Asia
    Adedolapo Aminat Rauff-Adedotun, Farah Haziqah Meor Termizi, Nurshafarina Shaari, Ii Li Lee
    Biology.2021; 10(10): 990.     CrossRef
  • 5,084 View
  • 81 Download
  • 11 Web of Science
  • Crossref

Original Articles

Comparative Microbiome Analysis of Three Species of Laboratory-Reared Periplaneta Cockroaches
Seogwon Lee, Ju Yeong Kim, Myung-hee Yi, In-Yong Lee, Won-Ja Lee, Hye Su Moon, Dongeun Yong, Tai-Soon Yong
Korean J Parasitol 2020;58(5):537-542.
Published online October 22, 2020
DOI: https://doi.org/10.3347/kjp.2020.58.5.537
Cockroaches inhabit various habitats, which will influence their microbiome. Although the microbiome can be influenced by the diet and environmental factors, it can also differ between species. Therefore, we conducted 16S rDNAtargeted high-throughput sequencing to evaluate the overall bacterial composition of the microbiomes of 3 cockroach species, Periplaneta americana, P. japonica, and P. fuliginosa, raised in laboratory for several generations under the same conditions. The experiments were conducted using male adult cockroaches. The number of operational taxonomic units (OTUs) was not significantly different among the 3 species. With regard to the Shannon and Pielou indexes, higher microbiome values were noted in P. americana than in P. japonica and P. fuliginosa. Microbiome composition was also evaluated, with endosymbionts accounting for over half of all OTUs in P. japonica and P. fuliginosa. Beta diversity analysis further showed that P. japonica and P. fuliginosa had similar microbiome composition, which differed from that of P. americana. However, we also identified that P. japonica and P. fuliginosa host distinct OTUs. Thus, although microbiome compositions may vary based on multiple conditions, it is possible to identify distinct microbiome compositions among different Periplaneta cockroach species, even when the individuals are reared under the same conditions.

Citations

Citations to this article as recorded by  Crossref logo
  • The Medical Importance of Cockroaches as Vectors of Pathogens: Implications for Public Health
    Dongfen Geng, Haotian Yu, Teng Zhao, Chunxiao Li
    Zoonoses.2025;[Epub]     CrossRef
  • Endosymbiont and gut bacterial communities of the brown-banded cockroach, Supella longipalpa
    Kylene Guse, Jose E. Pietri
    PeerJ.2024; 12: e17095.     CrossRef
  • Diversity, antibacterial and phytotoxic activities of actinomycetes associated with Periplaneta fuliginosa
    Qihua Liu, Jian Tao, Longhui Kan, Yinglao Zhang, Shuxiang Zhang
    PeerJ.2024; 12: e18575.     CrossRef
  • Composition and diversity of the gut microbiota across different life stages of American cockroach (Periplaneta americana)
    Zhiyu Chen, Sihao Wen, Juan Shen, Jie Wang, Wenbin Liu, Xiaobao Jin
    Bulletin of Entomological Research.2023; 113(6): 787.     CrossRef
  • Of Cockroaches and Symbionts: Recent Advances in the Characterization of the Relationship between Blattella germanica and Its Dual Symbiotic System
    Amparo Latorre, Rebeca Domínguez-Santos, Carlos García-Ferris, Rosario Gil
    Life.2022; 12(2): 290.     CrossRef
  • Differences in Gut Microbiome Composition Between Sympatric Wild and Allopatric Laboratory Populations of Omnivorous Cockroaches
    Kara A. Tinker, Elizabeth A. Ottesen
    Frontiers in Microbiology.2021;[Epub]     CrossRef
  • 5,721 View
  • 130 Download
  • 5 Web of Science
  • Crossref
Comparative Analysis of Pathogenic Organisms in Cockroaches from Different Community Settings in Edo State, Nigeria
Clement Isaac, Philip Ogbeide Orue, Mercy Itohan Iyamu, Joy Imuetiyan Ehiaghe, Osesojie Isaac
Korean J Parasitol 2014;52(2):177-181.
Published online April 18, 2014
DOI: https://doi.org/10.3347/kjp.2014.52.2.177

Cockroaches are abundant in Nigeria and are seen to harbour an array of pathogens. Environmental and sanitary conditions associated with demographic/socio-economic settings of an area could contribute to the prevalence of disease pathogens in cockroaches. A total of 246 cockroaches (Periplaneta americana) in urban (Benin, n=91), semi-urban (Ekpoma, n=75) and rural (Emuhi, n=70) settings in Edo State, Nigeria were collected within and around households. The external body surfaces and alimentary canal of these cockroaches were screened for bacterial, fungal, and parasitological infections. Bacillus sp. and Escherichia coli were the most common bacteria in cockroaches. However, Enterococcus faecalis could not be isolated in cockroaches trapped from Ekpoma and Emuhi. Aspergillus niger was the most prevalent fungus in Benin and Ekpoma, while Mucor sp. was predominant in Emuhi. Parasitological investigations revealed the preponderance of Ascaris lumbricoides in Benin and Emuhi, while Trichuris trichura was the most predominant in Ekpoma. The prevalence and burden of infection in cockroaches is likely to be a reflection of the sanitary conditions of these areas. Also, cockroaches in these areas making incursions in homes may increase the risk of human infections with these disease agents.

Citations

Citations to this article as recorded by  Crossref logo
  • Cockroach Microbiome Disrupts Indoor Environmental Microbial Ecology with Potential Public Health Implications
    Jiahui Ma, Mengzhen Wang, Ye Sun, Yunhao Zheng, Senchao Lai, Yingyi Zhang, Yan Wu, Chao Jiang, Fangxia Shen
    Environment & Health.2025; 3(4): 380.     CrossRef
  • SURVEY OF MEDICALLY IMPORTANT PROTOZOANS INFESTED ON COCKROACHES COLLECTED FROM STUDENT HOSTEL IN SA’ADU ZUNGUR UNIVERSITY, BAUCHI STATE
    Abdullahi Kamal, Aliyu Abdulhamid Omar, Abdullahi Shamsudden , Ladan Muhammad Auwal, Umar Aminu Mohammed, Abubakar Sadiq Yusuf, Umar Aliyu, Firdausi Zakari Ya’u
    FUDMA JOURNAL OF SCIENCES.2025; 9(2): 61.     CrossRef
  • The Medical Importance of Cockroaches as Vectors of Pathogens: Implications for Public Health
    Dongfen Geng, Haotian Yu, Teng Zhao, Chunxiao Li
    Zoonoses.2025;[Epub]     CrossRef
  • Comparison of the Effectiveness of Eucalyptus camaldulensis Extract and Dichlorvos (DDVP) in Controlling the Periplaneta americana
    A H Alwan, S M Lafta, E K Athab
    IOP Conference Series: Earth and Environmental Science.2025; 1538(1): 012076.     CrossRef
  • Urban Cockroaches as Reservoirs of Multidrug-Resistant Bacteria: Insights from Morphological and Molecular Characterization
    Jaweria Riaz, Mubashar Hussain, Aniza Iftikhar, Kiran Aftab, Suleman Hussain Shah, Sheeza Sakhawat, Amina Zafar, Aqsa Noreen
    Revista Brasileira de Entomologia.2025;[Epub]     CrossRef
  • Intestinal Parasites Associated with American Cockroach (Periplaneta americana) in Akure, Ondo State, Nigeria
    Adebayo Victor Akeju, Titus Adeniyi Olusi, Regina-Tyra Ekwi Obi
    Journal of Parasitic Diseases.2024; 48(1): 67.     CrossRef
  • Extended spectrum and metalo beta lactamase producing gram negative bacterial pathogens from cockroaches collected at hospital, Southern Ethiopia
    Fithamlak Solomon Bisetegn, Habtamu Azene, Khawaja Shakeel Ahmed, Fiseha Wadilo, Efrata Girma Tufa
    Antimicrobial Resistance & Infection Control.2024;[Epub]     CrossRef
  • De Novo Assembly and Characterization of the Transcriptome of an Omnivorous Camel Cricket (Tachycines meditationis)
    Jun-Hui Lu, De-Long Guan, Sheng-Quan Xu, Huateng Huang
    International Journal of Molecular Sciences.2023; 24(4): 4005.     CrossRef
  • Species composition and parasite carriage rate of cockroaches among households of Sekota town, Northeast Ethiopia
    Habtu Debash, Megbaru Alemu, Animen Ayehu
    International Journal of Tropical Insect Science.2022; 42(6): 3815.     CrossRef
  • A Systematic Review of Zoonotic Enteric Parasites Carried by Flies, Cockroaches, and Dung Beetles
    Avi Patel, Meg Jenkins, Kelly Rhoden, Amber N. Barnes
    Pathogens.2022; 11(1): 90.     CrossRef
  • Experimental studies to study the efficacy of "Tarzan, VE" against Blattoptera representatives
    R. M. Akbaev, L. V. Nacheva, A. A. Generalov
    Russian Journal of Parasitology.2021; 15(2): 80.     CrossRef
  • Protozoan Cysts in Faecal Pellets of German Cockroaches (Blattella germanica), with Particular Emphasis on Lophomonas blattarum
    Hugo Cornelis van Woerden, Rafael Martínez-Girón, Cristina Martínez-Torre
    Acta Parasitologica.2020; 65(4): 831.     CrossRef
  • Phenotypic and genotypic characterization of antibiotic resistance in the methicillin-resistant Staphylococcus aureus strains isolated from hospital cockroaches
    Zohreh Abdolmaleki, Zohreh Mashak, Farhad Safarpoor Dehkordi
    Antimicrobial Resistance & Infection Control.2019;[Epub]     CrossRef
  • Spatial Distribution and Prevalence of Parasites Vectored by Periplaneta americana in Southern, Nigeria: Implication for Intervention
    Ito Edore Edwin
    Asian Journal of Biological Sciences.2019; 12(2): 313.     CrossRef
  • Contamination of Cockroaches (Insecta: Blattaria) by Medically Important Bacteriae: A Systematic Review and Meta-analysis
    Hassan Nasirian, Michael Rust
    Journal of Medical Entomology.2019; 56(6): 1534.     CrossRef
  • Identification of Cockroaches as Mechanical Vector for Parasitic Infections and Infestations in Kuantan, Malaysia
    Afzan Mat Yusof
    Journal of Entomology.2018; 15(3): 143.     CrossRef
  • Isolation of bacteria from the digestive tract of Periplaneta americana and Polyphaga aegyptiaca (Blattodea: Blattidae) in Khuzestan Province, Southwestern Iran
    Arezo Elyasigomari, Davood Keshavarzi, Mustapha Ahmed Yusuf, Amir Hassanzadeh, Narges Marvi, Marzia Shahriari-Namadi, Zahra Nassiri
    Oriental Insects.2017; 51(4): 345.     CrossRef
  • Contamination of cockroaches (Insecta: Blattaria) to medically fungi: A systematic review and meta-analysis
    H. Nasirian
    Journal de Mycologie Médicale.2017; 27(4): 427.     CrossRef
  • The cockroach Periplaneta americana as a potential paratenic host of the lungworm Aelurostrongylus abstrusus
    Luigi Falsone, Vito Colella, Ettore Napoli, Emanuele Brianti, Domenico Otranto
    Experimental Parasitology.2017; 182: 54.     CrossRef
  • The prevalence of protozoa in the gut of German cockroaches (Blattella germanica) with special reference to Lophomonas blattarum
    Rafael Martínez-Girón, Cristina Martínez-Torre, Hugo Cornelis van Woerden
    Parasitology Research.2017; 116(11): 3205.     CrossRef
  • Cockroaches as a Source of High Bacterial Pathogens with Multidrug Resistant Strains in Gondar Town, Ethiopia
    Feleke Moges, Setegn Eshetie, Mengistu Endris, Kahsay Huruy, Dagnachew Muluye, Tigist Feleke, Fisha G/Silassie, Getenet Ayalew, Raja Nagappan
    BioMed Research International.2016; 2016: 1.     CrossRef
  • Cockroaches (Blattodea: Blattidae): A Reservoir of Pathogenic Microbes in Human-Dwelling Localities in Lahore
    H. Memona, F. Manzoor, A. A. Anjum
    Journal of Medical Entomology.2016; : tjw168.     CrossRef
  • 9,458 View
  • 125 Download
  • 19 Web of Science
  • Crossref
Enzymatic Activities of Allergen Extracts from Three Species of Dust Mites and Cockroaches Commonly Found in Korean Home
Kyoung Yong Jeong, Chungryul Kim, Tai-Soon Yong
Korean J Parasitol 2010;48(2):151-155.
Published online June 17, 2010
DOI: https://doi.org/10.3347/kjp.2010.48.2.151

Allergen extracts from dust mites and cockroaches commonly found in Korean homes were used to evaluate their enzymatic activity as they are believed to influence allergenicity. Allergen extracts were prepared from 3 dust mite species (Dermatophagoides farinae, D. pteronyssinus, and Tyrophagus putrescentiae) and 3 cockroach species (Blattella germanica, Periplaneta americana, and P. fuliginosa) maintained in the Korea National Arthropods of Medical Importance Resource Bank. Proteins were extracted in PBS after homogenization using liquid nitrogen. The activities of various enzymes were investigated using the API Zym system. No significant difference in phosphatase, lipase, or glycosidase activity was observed among the 6 allergen extracts, but much difference was observed in protease activity. Protease activity was assessed in more detail by gelatin zymography and the EnzChek assay. Extract from T. putrescentiae showed the highest protease activity, followed by those of the cockroach extracts. Extracts from D. farinae and D. pteronyssinus showed only weak protease activity. Gelatinolytic activity was detected mainly in a 30-kDa protein in D. farinae, a 28-kDa protein in D. pteronyssinus, a > 26-kDa protein in T. putrescentiae, a > 20-kDa protein in B. germanica, and a > 23-kDa protein in P. americana and P. fuliginosa. The information on various enzymatic activities obtained in this study may be useful for future studies. In particular, the strong protease activity found in cockroach extracts could contribute to sensitization to cockroach allergens, which is known to be associated with the development of asthma.

Citations

Citations to this article as recorded by  Crossref logo
  • B-cell antibody class switchings are pressuromodulated events: Part II, gene recombination
    Hemant Sarin
    Translational Medicine Communications.2018;[Epub]     CrossRef
  • Allergenic Characterization of a Novel Allergen, Homologous to Chymotrypsin, from German Cockroach
    Kyoung Yong Jeong, Mina Son, Jae-Hyun Lee, Chein-Soo Hong, Jung-Won Park
    Allergy, Asthma & Immunology Research.2015; 7(3): 283.     CrossRef
  • Current Status of Standardization of Inhalant Allergen Extracts in Korea
    Kyoung Yong Jeong, Jae-Hyun Lee, Eun-Jin Kim, Joo-Shil Lee, Sang-Heon Cho, Soo-Jong Hong, Jung-Won Park
    Allergy, Asthma & Immunology Research.2014; 6(3): 196.     CrossRef
  • Preparation and Characterization of an Extract of German Cockroach From a Korean Source
    Kyoung Yong Jeong, Soo-Young Choi, Jae-Hyun Lee, Joo-Shil Lee, Tai-Soon Yong, Chein-Soo Hong, Jung-Won Park
    Allergy, Asthma & Immunology Research.2013; 5(2): 102.     CrossRef
  • The Effects of Storage Conditions on the Stability of House Dust Mite Extracts
    Kyoung Yong Jeong, Soo-Young Choi, In-Soo Han, Jae-Hyun Lee, Joo-Shil Lee, Chein-Soo Hong, Jung-Won Park
    Allergy, Asthma & Immunology Research.2013; 5(6): 397.     CrossRef
  • House Dust Mite Allergy in Korea: The Most Important Inhalant Allergen in Current and Future
    Kyoung Yong Jeong, Jung-Won Park, Chein-Soo Hong
    Allergy, Asthma & Immunology Research.2012; 4(6): 313.     CrossRef
  • Role of Cockroach Proteases in Allergic Disease
    Kristen Page
    Current Allergy and Asthma Reports.2012; 12(5): 448.     CrossRef
  • Optimization of Allergen Standardization
    Kyoung Yong Jeong, Chein-Soo Hong, Joo-Shil Lee, Jung-Won Park
    Yonsei Medical Journal.2011; 52(3): 393.     CrossRef
  • 9,148 View
  • 82 Download
  • Crossref

Mini Review

Household Arthropod Allergens in Korea
Tai-Soon Yong, Kyoung Yong Jeong
Korean J Parasitol 2009;47(Suppl):S143.
Published online October 26, 2009
DOI: https://doi.org/10.3347/kjp.2009.47.S.S143

Arthropods are important in human health, which can transmit pathogens to humans, parasitize, or produce important allergens. Allergy prevalence becomes higher in Korea recently as well as other developed countries in contrast to a decrease of infectious diseases. Allergic diseases caused by household arthropods have increased dramatically during the last few decades since human beings spend more their time for indoor activities in modernized life style. Household arthropods are one of the most common causes of allergic diseases. Biological characterization of household arthropods and researches on their allergens will provide better understanding of the pathogenesis of allergic diseases and suggest new therapeutic ways. Therefore, studies on arthropods of allergenic importance can be considered one of the major research areas in medical arthropodology and parasitology. Here, the biology of several household arthropods, including house dust mites and cockroaches, the 2 most well known arthropods living indoor together with humans worldwide, and characteristics of their allergens, especially the research activities on these allergens performed in Korea, are summarized.

Citations

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  • The Identification of Potential Immunogenic Antigens in Particular Active Developmental Stages of the Rice Weevil (Sitophilus oryzae)
    Joanna Witecka, Natalia Malejky-Kłusek, Krzysztof Solarz, Olga Pawełczyk, Małgorzata Kłyś, Aleksandra Izdebska, Weronika Maślanko, Marek Asman
    International Journal of Environmental Research and Public Health.2023; 20(5): 3917.     CrossRef
  • Multiple allergen simultaneous test is useful in assessing allergen sensitization and its geographic variations by the Geographic Information System-based approach
    Sung-Yoon Kang, Jae-Woo Kwon, Jeong-Hun Lim, Hyeong-Nyeon Kim, Sung-Geun Jung, Jae-Won Jeong
    Allergy, Asthma & Respiratory Disease.2023; 11(3): 135.     CrossRef
  • Trends and Associated Factors of Under-five Mortality Based on 2008–2016 Data in Kersa Health and Demographic Surveillance Site, Eastern Ethiopia
    Gebisa Dirirsa Gutema, Abraham Geremew, Dechasa Adare Mengistu, Yohannes Mulugeta Dammu, Kefelegn Bayu
    INQUIRY: The Journal of Health Care Organization, Provision, and Financing.2022;[Epub]     CrossRef
  • The Influence of Indoor Environmental Factors on the Prevalence of House Dust Mites as Aeroallergens in Bandar Abbas Student Dormitories, South of Iran, 2019
    Mehdi Zare, Mehdi Hassani-Azad, Moussa Soleimani-Ahmadi, Raziea Majnoon, Monika Gulia-Nuss
    Journal of Medical Entomology.2021; 58(4): 1865.     CrossRef
  • Comparison of inhalant allergen sensitization between children, adolescents, and adults with asthma and allergic rhinitis
    Na Gyeom Lee, Hee-Kyoo Kim, Gil Soon Choi
    Allergy, Asthma & Respiratory Disease.2021; 9(3): 148.     CrossRef
  • Changes in allergen sensitization in children with allergic diseases in the 1980 to 2019
    Jae Hwa Jung, Ga Eun Kim, Mireu Park, Soo Yeon Kim, Min Jung Kim, Yong Ju Lee, Yoon Hee Kim, Kyung Won Kim, Myung Hyun Sohn
    Allergy, Asthma & Respiratory Disease.2021; 9(4): 208.     CrossRef
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    Abdolazim Mortazavi Lahijani, Ramin Khaghani, Hamidreza Hajiqanbar, Seyed Shahram Mirzamani
    Annals of Military and Health Sciences Research.2019;[Epub]     CrossRef
  • Glutathione S-transferase (GST) of American Cockroach, Periplaneta americana: Classes, Isoforms, and Allergenicity
    Nitat Sookrung, Onrapak Reamtong, Rojana Poolphol, Nitaya Indrawattana, Watee Seesuay, Nawannaporn Saelim, Pongsakorn Tantilipikorn, Chaweewan Bunnag, Wanpen Chaicumpa, Anchalee Tungtrongchitr
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    Meir Paul Pener
    Journal of Orthoptera Research.2016; 25(2): 91.     CrossRef
  • Repellent effect of Mate tea and Jasmine tea against house dust mites (Dermatophagoides farinae and D. pteronyssinus)
    Sook Jae Lee, Cha Ho Jee
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    Woo-Jung Song, Kyoung-Hee Sohn, Min-Gyu Kang, Han-Ki Park, Mi-Yeong Kim, Sae-Hoon Kim, Min Kyung Lim, Min-Ho Choi, Ki Woong Kim, Sang-Heon Cho, Kyung-Up Min, Yoon-Seok Chang
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    Hye-Sung Kim, Cha-Ho Jee
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    CHUNG-RYUL KIM, KYOUNG YONG JEONG, MYUNG-HEE YI, HYOUNG-PYO KIM, HO-JOON SHIN, TAI-SOON YONG
    Molecular Medicine Reports.2015; 12(4): 5467.     CrossRef
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  • The differences of clinical profiles by house dust mite sensitization in patients with asthmatics in Soonchunhyang University Hospital cohort
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    Ljerka Prester
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    Rubaba Hamid Shafique, Muhammad Inam, Muhammad Ismail, Farhana Riaz Chaudhary
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  • Review on Ecology of House Dust Mites in Korea and Suggestion of a Standard Survey Method
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    Molecular Immunology.2011; 48(15-16): 1983.     CrossRef
  • 11,945 View
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Original Article

Reactivity of German Cockroach Allergen, Bla g 2, Peptide Fragments to IgE Antibodies in Patients' Sera
Haeseok Lee, Kyoung Yong Jeong, Kwang Hyun Shin, Myung-hee Yi, Darambazar Gantulaga, Chein-Soo Hong, Tai-Soon Yong
Korean J Parasitol 2008;46(4):243-246.
Published online December 20, 2008
DOI: https://doi.org/10.3347/kjp.2008.46.4.243

Bla g 2 is a cockroach allergen of great importance. This study was conducted to identify IgE-binding epitope(s) of Bla g 2 using the recombinant protein technique. Approximately 50% of tested sera showed IgE reactivity to Pichia-expressed Bla g 2 (PrBla g 2) and E. coli-expressed Bla g 2 (ErBla g 2). Only 5.3% of serum samples showed stronger reactivity to PrBla g 2 than ErBla g 2, indicating that serum was reactive to conformational or carbohydrate epitopes. The full-length and 5 peptide fragments of Bla g 2 were produced in E. coli. All fragments showed IgE-binding activity to the cockroach-allergy patients' sera. Specifically, peptide fragments of amino acid residue 1-75 and 146-225 appeared to be important for IgE-binding. The information about the IgE-binding epitope of Bla g 2 can aid in the diagnosis and treatment for cockroach allergies.

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  • IgE-Binding Epitope Mapping and Tissue Localization of the Major American Cockroach Allergen Per a 2
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  • Different Bla‐g T cell antigens dominate responses in asthma versus rhinitis subjects
    M. B. C. Dillon, V. Schulten, C. Oseroff, S. Paul, L. M. Dullanty, A. Frazier, X. Belles, M.‐D. Piulachs, C. Visness, L. Bacharier, G. R. Bloomberg, P. Busse, J. Sidney, B. Peters, A. Sette
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  • Preparation and Characterization of an Extract of German Cockroach From a Korean Source
    Kyoung Yong Jeong, Soo-Young Choi, Jae-Hyun Lee, Joo-Shil Lee, Tai-Soon Yong, Chein-Soo Hong, Jung-Won Park
    Allergy, Asthma & Immunology Research.2013; 5(2): 102.     CrossRef
  • Identification of Novel Allergenic Components from German Cockroach Fecal Extract by a Proteomic Approach
    Kyoung Yong Jeong, Chung-ryul Kim, Jina Park, In-Soo Han, Jung-Won Park, Tai-Soon Yong
    International Archives of Allergy and Immunology.2013; 161(4): 315.     CrossRef
  • The Cockroach and Allergic Diseases
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    Allergy, Asthma & Immunology Research.2012; 4(5): 264.     CrossRef
  • Validation of a Phage Display and Computational Algorithm by Mapping a Conformational Epitope of Bla g 2
    Ruby Tiwari, Surendra S. Negi, Benjamin Braun, Werner Braun, Anna Pomés, Martin D. Chapman, Randall M. Goldblum, Terumi Midoro-Horiuti
    International Archives of Allergy and Immunology.2012; 157(4): 323.     CrossRef
  • Sensitization to per a 2 of the American cockroach correlates with more clinical severity among airway allergic patients in Taiwan
    Mey-Fann Lee, Pei-Peng Song, Guang-Yuh Hwang, Shyh-Jye Lin, Yi-Hsing Chen
    Annals of Allergy, Asthma & Immunology.2012; 108(4): 243.     CrossRef
  • Household Arthropod Allergens in Korea
    Tai-Soon Yong, Kyoung Yong Jeong
    The Korean Journal of Parasitology.2009; 47(Suppl): S143.     CrossRef
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  • 86 Download
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Case Report

A case of Moniliformis moniliformis (Acanthocephala) infection in Iran
Fariba Berenji, Abdolmajid Fata, Zahra Hosseininejad
Korean J Parasitol 2007;45(2):145-148.
Published online June 20, 2007
DOI: https://doi.org/10.3347/kjp.2007.45.2.145

Only a few cases of Acanthocephala infections have been reported in humans, and Moniliformis moniliformis is the most common species around the world. We report here a case of infection with M. moniliformis, which passed in the stool of a 2-year-old girl in Iran. The patient had abdominal pain, diarrhea, vomiting, and facial edema. According to her mother, the patient had habit of eating dirt and once a cockroach was discovered in her mouth. In stool examination, eggs of M. moniliformis were not found. She was treated with levamisole and the clinical symptoms reduced within 2 weeks. The specimen contained 2 pieces of a female worm with a total length of 148 mm lacking the posterior end. The spiral musculature of the proboscis receptacle and the shape of the trunk allowed its generic determination. Previously 2 cases of M. moniliformis infection were reported in Iran. This is the 3rd case of M. moniliformis infection in Iran.

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    Heliyon.2024; 10(11): e31955.     CrossRef
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    Božana Tošić, Borislav Čabrilo, Milan Miljević, Marija Rajičić, Branka Bajić, Ivana Budinski, Olivera Bjelić-Čabrilo
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Brief Communication

Field trial on the control effect of fipronil bait against German cockroaches
Han-Il Ree, In-Yong Lee, Soung-Hoo Jeon, Tai-Soon Yong
Korean J Parasitol 2006;44(3):255-257.
Published online September 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.3.255

A field trial on the control effect of fipronil poison bait against German cockroaches (Blatella germanica) was carried out at different restaurant types in Sinchon, Seoul, Republic of Korea. Monitoring was performed applying food baited traps for 2 days per week. Reduction rates of German cockroaches by applying fipronil baits were 90.9% at Korean restaurants, 96.4% at Chinese restaurants, and 89.4% in beer hall kitchens after 4 weeks of the treatment. Overall average of the reduction rate was 93.9%. As the natural reduction rate at untreated restaurants was 11.5% after 4 weeks, a correction of the average reduction rate by applying the Abbot formula was 93.1%.

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  • Insecticidal action of beer towards different aphid species
    D. Ganchev
    Agricultural Science and Technology.2022; 14(4): 43.     CrossRef
  • Development of Fipronil Gel Bait Against German Cockroaches, Blattella germanica (Dictyoptera: Blattellidae): Laboratory and Field Performance in Bandung, Indonesia
    Intan Ahmad, Suliyat .
    Journal of Entomology.2011; 8(3): 288.     CrossRef
  • Permethrin Induces Overexpression of Cytochrome c Oxidase Subunit 3 in Aedes aegypti
    Julia W. Pridgeon, James J. Becnel, Gary G. Clark, Kenneth J. Linthicum
    Journal of Medical Entomology.2009; 46(4): 810.     CrossRef
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    Kazuhiko Tarora, Norio Arakaki, Kazumi Uehara, Masato Ishimine, Aya Kobayashi, Atsushi Nagayama
    Japanese Journal of Applied Entomology and Zoology.2007; 51(2): 129.     CrossRef
  • 6,909 View
  • 63 Download
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Original Article

Effectiveness of education for control of house dust mites and cockroaches in Seoul, Korea
Kyoung Yong Jeong, In-Yong Lee, Jongweon Lee, Han-Il Ree, Chein-Soo Hong, Tai-Soon Yong
Korean J Parasitol 2006;44(1):73-79.
Published online March 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.1.73

We evaluated the efficacy of health education in reducing indoor arthropod allergens in Seoul. The mite control measures comprised the use of mite-proof mattress and pillow coverings, regular washing of potentially infested materials, maintenance of a low humidity, removal of carpets, and frequent vacuum cleaning. Cockroach control measures included trapping, application of insecticides, and protecting food. Of 201 homes enrolled in October 1999, 63 volunteers were included in a 2-year follow-up survey between April 2000 and January 2002. Before intervention, the density of mites/g of dust varied greatly; 27.1/g in children's bedding, 20/g in adult bedding, 7.2/g on the floors of children's bedrooms, 6.8/g in sofas, 5.9/g on the floors of adult's bedrooms, 3.9/g on living room floors, 3.7/g in carpets, and 1.9 mites/g on kitchen floors. The predominant mite species and house percentages infested were; Dermatophagoides farinae 93%, D. pteronyssinus 9%, and Tyrophagus putrescentiae 8%. Comparing 1999 and 2001 infestations, before and after 25 mo of education, mite abundance was reduced by 98%, from 23.7 to 0.57 mites/g of dust. In 1999, cockroaches were detected in 62% homes: 36% Blattella germanica and 35% Periplaneta spp., including 9% double infestations of B. germanica and P. americana. Following intervention, cockroach infestation rates decreased to 22% of houses in 2000 and 23% in 2001. We conclude that continuous and repetitive health education resulted in the effective control of domestic arthropods.

Citations

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    Eun-Min Kim, Ju Yeong Kim, You Shine Kwak, Myung-Hee Yi, Tai-Soon Yong
    Parasites, Hosts and Diseases.2024; 62(3): 365.     CrossRef
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    Myung-hee Yi, Myungjun Kim, Tai-Soon Yong, Ju Yeong Kim
    Frontiers in Allergy.2023;[Epub]     CrossRef
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    Ju Yeong Kim, Myung‐hee Yi, Seogwon Lee, In‐Yong Lee, Dongeun Yong, Sang Sun Yoon, Tai‐Soon Yong
    Clinical & Experimental Allergy.2021; 51(12): 1592.     CrossRef
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    Mey-Fann Lee, Yi-Hsing Chen, Shyh-Jye Lin, Hsin-Chun Liu, Tzu-Mei Lin
    Annals of Allergy, Asthma & Immunology.2019; 123(3): 301.     CrossRef
  • Infestation of cockroaches (Insecta: Blattaria) in the human dwelling environments: A systematic review and meta-analysis
    Hassan Nasirian
    Acta Tropica.2017; 167: 86.     CrossRef
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    Ammorn INSUNG, Jarongsak PUMNUAN, Vanna MAHAKITTIKUN, Teerapong WANGAPAI
    Journal of the Acarological Society of Japan.2016; 25(Supplement): S179.     CrossRef
  • The effects of a newsletter on bedding control on house dust mite allergen concentrations in childcare centers in Korea
    Jeonghoon Kim, Kyoung Yong Jeong, Ho-Jang Kwon, Heasuk Yang, Hye Yung Yum, Seon Ah Lee, Chae-Bong Kim, Hyunjung Kim, Wan Ryung Lim, Soyoung Hong, Kyoosang Kim
    Environmental Health and Toxicology.2015; 30: e2015008.     CrossRef
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    Anna Pomés, Luisa Karla Arruda
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    Experimental and Applied Acarology.2014; 63(1): 57.     CrossRef
  • The differences of clinical profiles by house dust mite sensitization in patients with asthmatics in Soonchunhyang University Hospital cohort
    Jung-Hyun Kim, An-Soo Jang, Shin-Ok Jeong, Young-Seok Ji, Hyun-Jung Seo, Jae-Hyung Nam, Jong-Joo Moon, Ae-Rin Baek, Jong-Sook Park, June-Hyuk Lee, Sung-Woo Park, Do-Jin Kim, Choon-Sik Park
    Allergy Asthma & Respiratory Disease.2013; 1(1): 50.     CrossRef
  • Preparation and Characterization of an Extract of German Cockroach From a Korean Source
    Kyoung Yong Jeong, Soo-Young Choi, Jae-Hyun Lee, Joo-Shil Lee, Tai-Soon Yong, Chein-Soo Hong, Jung-Won Park
    Allergy, Asthma & Immunology Research.2013; 5(2): 102.     CrossRef
  • Effect of a commercial air ionizer on dust mites Dermatophagoides pteronyssinus and Dermatophagoides farinae (Acari: Pyroglyphidae) in the laboratory
    Suhaili Zainal Abidin, Ho Tze Ming
    Asian Pacific Journal of Tropical Biomedicine.2012; 2(2): 156.     CrossRef
  • The Cockroach and Allergic Diseases
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    Allergy, Asthma & Immunology Research.2012; 4(5): 264.     CrossRef
  • Group 10 Allergens (Tropomyosins) from House-Dust Mites May Cause Covariation of Sensitization to Allergens from Other Invertebrates
    Rubaba Hamid Shafique, Muhammad Inam, Muhammad Ismail, Farhana Riaz Chaudhary
    Allergy & Rhinology.2012;[Epub]     CrossRef
  • Review on Ecology of House Dust Mites in Korea and Suggestion of a Standard Survey Method
    Tai-Soon Yong, Kyoung-Yong Jeong
    Pediatric Allergy and Respiratory Disease.2011; 21(1): 4.     CrossRef
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    Tai-Soon Yong, Kyoung Yong Jeong
    The Korean Journal of Parasitology.2009; 47(Suppl): S143.     CrossRef
  • 10,263 View
  • 96 Download
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Brief Communication
Prevalence of arthropod antibodies in Korean patients with allergic rhinitis
Kyu-Yoon Hwang, Joon-Soo Park, Hyun-Cheol Ahn, Hae-Seon Nam
Korean J Parasitol 2001;39(2):197-199.
Published online June 30, 2001
DOI: https://doi.org/10.3347/kjp.2001.39.2.197

Arthropod antigens are main causative agents which induce allergic reponses in humans. However, little information is known about the prevalence of specific arthropod allergens in Koreans with allergic diseases. The current study was designed to determine the positive rates of arthropod antibodies by the Korean inhalant panel of MAST-CLA. One hundred sixty patients, who were diagnosed with allergic rhinitis from an out-patient center at the Soonchunhyang University Chunan Hospital, were studied between August 1998 to July 2000. The overall positive rate, at least more than one specific antibody of arthropods such as Dermatophagoides farinae (Df), Dermatophagoides pteronyssinus (Dp), and cockroach mix (Cm), was 46.9%. Each positive rate of Df, Dp, and Cm was 45.0%, 43.1%, and 8.8%, respectively. A significant agreement among arthropod allergens was observed (Df and Dp: 95.6%, Kappa = 0.911, P < 0.001). Our data supported the fact that arthropods were the most common allergens in Korean patients with allergic rhinitis; however, the MAST-CLA should be modified to increase specificity of arthropod allergens.

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  • Validity of MAST-CLA for diagnosis of arthropod allergy using receiver operating characteristic (ROC) analysis
    Joon-Soo Park, Hae-Seon Nam, Yong-Bae Kim, Young-Jin Choi, Sang-Han Lee, Sung-Ho Kim
    The Korean Journal of Parasitology.2007; 45(3): 239.     CrossRef
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