Parasites, Hosts and Diseases

"hypersensitivity"

Brief Communication

Chronic Toxoplasmosis Modulates the Induction of Contact Hypersensitivity by TNCB in Mouse Model: Zhaoshou Yang, Hye-Jin Ahn, Ho-Woo Nam; Korean J Parasitol 2015;53(6):755-757.
Published online December 31, 2015; DOI: https://doi.org/10.3347/kjp.2015.53.6.755

Abstract
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Mouse models of chronic toxoplasmosis and atopic dermatitis (AD) were combined to clarify the effect of opportunistic Toxoplama gondii infection on the development of AD. AD was induced as a chronic contact hypersensitivity (CHS) with repeated challenge of 2,4,6-trinitro-1-chlorobenzene (TNCB) on the dorsal skin of mice. TNCB induced skin thickness increases in both normal and toxoplasmic mice. The changing patterns were different from the sigmoidal which saturated at 20 days in normal mice to the convex saturated at 12 days in toxoplasmic mice with the crossing at 18 days. Compared to normal mice, toxoplasmic mice presented CHS more severely in earlier times and then moderately in later times. These data suggest that host immune modification by T. gondii infection enhances CHS in early times of atopic stimulation but soothes the reaction of CHS in later times in mouse model.

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Effect of orally administered exopolysaccharides produced by Lactococcus lactis subsp. cremoris FC on a mouse model of dermatitis induced by repeated exposure to 2,4,6-trinitro-1-chlorobenzene
Yayoi Gotoh, Shiho Suzuki, Midori Amako, Shinichi Kitamura, Toshiya Toda
Journal of Functional Foods.2017; 35: 43. CrossRef

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Original Article

Leishmania tropica infection, in comparison to Leishmania major, induces lower delayed type hypersensitivity in BALB/c mice: Hamid Mahmoudzadeh-Niknam, Simin Sadat Kiaei, Davood Iravani; Korean J Parasitol 2007;45(2):103-109.
Published online June 20, 2007; DOI: https://doi.org/10.3347/kjp.2007.45.2.103

Abstract
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Leishmania tropica and L. major are etiologic agents of human cutaneous leishmaniasis. Delayed type hypersensitivity (DTH) is an immunologic response that has been frequently used as a correlate for protection against or sensitization to leishmania antigen. In BALB/c mice, L. tropica infection results in non-ulcerating disease, whereas L. major infection results in destructive lesions. In order to clarify the immunologic mechanisms of these 2 different outcomes, we compared the ability of these 2 leishmania species in induction of DTH response in this murine model. BALB/c mice were infected with L. major or L. tropica, and disease evolution and DTH responses were determined. The results show that the primary L. major infection can exacerbate the secondary L. major infection and is associated with DTH response. Higher doses of the primary L. major infection result in more disease exacerbation of the secondary L. major infection as well as higher DTH response. L. tropica infection induces lower DTH responses than L. major. We have previously reported that the primary L. tropica infection induces partial protection against the secondary L. major infection in BALB/c mice. Induction of lower DTH response by L. tropica suggests that the protection induced against L. major by prior L. tropica infection may be due to suppression of DTH response.

Citations

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Expression of key cytokines in dog macrophages infected by Leishmania tarentolae opening new avenues for the protection against Leishmania infantum
Viviane Noll Louzada-Flores, Maria Stefania Latrofa, Jairo Alfonso Mendoza-Roldan, Maria Stella Lucente, Sara Epis, Ilaria Varotto-Boccazzi, Claudio Bandi, Domenico Otranto
Scientific Reports.2024;[Epub] CrossRef
Interspecies and Intrastrain Interplay among Leishmania spp. Parasites
Bruna Dias das Chagas, Thaís Martins Pereira, Lilian Motta Cantanhêde, Gabriela Pereira da Silva, Mariana Côrtes Boité, Luiza de Oliveira Ramos Pereira, Elisa Cupolillo
Microorganisms.2022; 10(10): 1883. CrossRef
Integration of Bioinformatics and in vitro Analysis Reveal Anti-leishmanial Effects of Azithromycin and Nystatin
Irum Jehangir, Syed Farhan Ahmad, Maryam Jehangir, Anwar Jamal, Momin Khan
Current Bioinformatics.2019; 14(5): 450. CrossRef
Vaccination with whole-cell killed or recombinant leishmanial protein and toll-like receptor agonists against Leishmania tropica in BALB/c mice
Mosayeb Rostamian, Fariborz Bahrami, Hamid M. Niknam, Humberto Lanz-Mendoza
PLOS ONE.2018; 13(9): e0204491. CrossRef
Route of Infection Affects Pathogenicity of Leishmania major in BALB/c Mice
Ehsan Sarreshteh, Mosayeb Rostamian, Mahsa Tat Asadi, Firoozeh Abrishami, Ali Najafi, Maryam Abolghazi, Hamid Mahmoudzadeh Niknam
Journal of Medical Microbiology and Infectious Diseases .2017; 5(1): 26. CrossRef
Studies on cocktails of 31‐kDa, 36‐kDa and 51‐kDa antigens of Leishmania donovani along with saponin against murine visceral leishmaniasis
H. Kaur, A. Thakur, S. Kaur
Parasite Immunology.2015; 37(4): 192. CrossRef
A Review: The Current In Vivo Models for the Discovery and Utility of New Anti-leishmanial Drugs Targeting Cutaneous Leishmaniasis
Emily Rose Mears, Farrokh Modabber, Robert Don, George E. Johnson, Louis Maes
PLOS Neglected Tropical Diseases.2015; 9(9): e0003889. CrossRef
Studies on the protective efficacy of second-generation vaccine along with standard antileishmanial drug in Leishmania donovani infected BALB/c mice
JYOTI JOSHI, SUKHBIR KAUR
Parasitology.2014; 141(4): 554. CrossRef
The Route of Leishmania tropica Infection Determines Disease Outcome and Protection against Leishmania major in BALB/c Mice
Hamid Mahmoudzadeh-Niknam, Ghader Khalili, Firoozeh Abrishami, Ali Najafy, Vahid Khaze
The Korean Journal of Parasitology.2013; 51(1): 69. CrossRef
Antineoplastic drug, carboplatin, protects mice against visceral leishmaniasis
Tejinder Kaur, Prerna Makkar, Kulbir Randhawa, Sukhbir Kaur
Parasitology Research.2013; 112(1): 91. CrossRef
Protective immunity against Leishmania major induced by Leishmania tropica infection of BALB/c mice
Hamid Mahmoudzadeh-Niknam, Simin Sadat Kiaei, Davood Iravani
Experimental Parasitology.2011; 127(2): 448. CrossRef
FML vaccine against canine visceral leishmaniasis: from second-generation to synthetic vaccine
Clarisa B Palatnik-de-Sousa, André de Figueiredo Barbosa, Sandra Maria Oliveira, Dirlei Nico, Robson Ronney Bernardo, Wania R Santos, Mauricio M Rodrigues, Irene Soares, Gulnara P Borja-Cabrera
Expert Review of Vaccines.2008; 7(6): 833. CrossRef
Viscerotropic growth pattern of Leishmania tropica in BALB/c mice is suggestive of a murine model for human viscerotropic leishmaniasis
Hamid Mahmoudzadeh-Niknam, Simin Sadat Kiaei, Davood Iravani
The Korean Journal of Parasitology.2007; 45(4): 247. CrossRef

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Brief Communication

Prevalence of arthropod antibodies in Korean patients with allergic rhinitis: Kyu-Yoon Hwang, Joon-Soo Park, Hyun-Cheol Ahn, Hae-Seon Nam; Korean J Parasitol 2001;39(2):197-199.
Published online June 30, 2001; DOI: https://doi.org/10.3347/kjp.2001.39.2.197

Abstract
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Arthropod antigens are main causative agents which induce allergic reponses in humans. However, little information is known about the prevalence of specific arthropod allergens in Koreans with allergic diseases. The current study was designed to determine the positive rates of arthropod antibodies by the Korean inhalant panel of MAST-CLA. One hundred sixty patients, who were diagnosed with allergic rhinitis from an out-patient center at the Soonchunhyang University Chunan Hospital, were studied between August 1998 to July 2000. The overall positive rate, at least more than one specific antibody of arthropods such as Dermatophagoides farinae (Df), Dermatophagoides pteronyssinus (Dp), and cockroach mix (Cm), was 46.9%. Each positive rate of Df, Dp, and Cm was 45.0%, 43.1%, and 8.8%, respectively. A significant agreement among arthropod allergens was observed (Df and Dp: 95.6%, Kappa = 0.911, P < 0.001). Our data supported the fact that arthropods were the most common allergens in Korean patients with allergic rhinitis; however, the MAST-CLA should be modified to increase specificity of arthropod allergens.

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Validity of MAST-CLA for diagnosis of arthropod allergy using receiver operating characteristic (ROC) analysis
Joon-Soo Park, Hae-Seon Nam, Yong-Bae Kim, Young-Jin Choi, Sang-Han Lee, Sung-Ho Kim
The Korean Journal of Parasitology.2007; 45(3): 239. CrossRef

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Original Article

Identification of Chironomus kiiensis allergens, a dominant species of non-biting midges in Korea: Tai-Soon Yong, Jong-Seok Lee, In-Yong Lee, Soon-Jung Park, Gab-Man Park, Han-Il Ree, Jung-Won Park, Chein-Soo Hong, Hae-Sim Park; Korean J Parasitol 1999;37(3):171-179.
Published online September 30, 1999; DOI: https://doi.org/10.3347/kjp.1999.37.3.171

Abstract
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Non-biting midges are known to contain potent inhalant allergens. IgE antibody responses to the crude extract of Chironomus kiiensis adults, a dominant chironomid species in Korea, were examined. With the IgE-ELISA or passive cutaneous anaphylaxis reactions, increased levels of chironomid-specific IgE were detected in the skin test positive human sera, or immunized BALB/c mouse sera with the crude extract adsorbed to alum. IgE-immunoblot analysis showed major IgE-reacting protein band patterns, which reacted with more than 50% of the skin test positive human sera, at 110, 80, 73, 46, 40, 37, 34, and 31 kDa. The reactive band patterns were largely similar between skin test positive humans and immune BALB/c mice. However, the bands of 55, 31, 27, 26, 24, and 23 kDa were found only in sensitized humans, but not in immunized mice.

Citations

Citations to this article as recorded by

Les allergènes croisants des insectes comestibles
A. Barre, E. Velazquez, A. Delplanque, S. Caze-Subra, F. Bienvenu, J. Bienvenu, H. Benoist, P. Rougé
Revue Française d'Allergologie.2016; 56(7-8): 522. CrossRef
Haemoglobin, a new major allergen of Anisakis simplex
Juan González-Fernández, Alvaro Daschner, Natalie E. Nieuwenhuizen, Andreas L. Lopata, Consolación De Frutos, Ana Valls, Carmen Cuéllar
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An Asiatic Chironomid in Brazil: morphology, DNA barcode and bionomics
Gizelle Amora, Neusa Hamada, Lívia Maria Fusari, Vanderly Andrade-Souza
ZooKeys.2015; 514: 129. CrossRef
L’effet inflammatoire de l’extrait brut de Phaenopsectra flavipes (Diptera : Chironomidae) du Nord-Est algérien, chez un modèle murin (Mus musculus)
Z. Bensakhri, K. Zerguine, I. Bouguenoun, D. Bendjeddou
Revue Française d'Allergologie.2014; 54(7): 485. CrossRef
Six new and two newly recorded species of Chironomidae (Insecta: Diptera) in Korea
Han Il Ree
Entomological Research.2013; 43(6): 322. CrossRef
Two New and Four Unrecorded Species of Chironomidae (Diptera) in Korea
Han-Il Ree, Sung-Hyun Nam, Kyoung-Yong Jeong
Animal Systematics, Evolution and Diversity.2012; 28(1): 2. CrossRef
Eight New and Four Newly Recorded Species of Chironomidae (Insecta: Diptera) from Korea
Han Il Ree
Animal Systematics, Evolution and Diversity.2012; 28(4): 241. CrossRef
Household Arthropod Allergens in Korea
Tai-Soon Yong, Kyoung Yong Jeong
The Korean Journal of Parasitology.2009; 47(Suppl): S143. CrossRef
Molecular Cloning and Characterization of Tropomyosin, a Major Allergen of Chironomus kiiensis , a Dominant Species of Nonbiting Midges in Korea
Kyoung Yong Jeong, Hye-Yung Yum, In-Yong Lee, Han-Il Ree, Chein-Soo Hong, Dong Soo Kim, Tai-Soon Yong
Clinical and Vaccine Immunology.2004; 11(2): 320. CrossRef