Parasites, Hosts and Diseases

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Case Reports

Painless Jaundice Caused by Clonorchis sinensis Infection: A Case Report: Yuhua Hao, Wanguo Bao, Meishan Jin, Yuxiang Li, Feng Wang; Korean J Parasitol 2016;54(3):323-327.
Published online June 30, 2016; DOI: https://doi.org/10.3347/kjp.2016.54.3.323

Abstract
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A man with only yellowing of the skin and eye sclera was diagnosed with clonorchiasis, which rarely manifested jaundice as the initial symptom. However, because of a lack of evidence for a diagnostic gold standard, the time until definitive diagnosis was more than a week. The diagnostic process relied on inquiring about the patient’s history, including the place of residence, dietary habits, and symptoms, as well as on serological findings, an imaging examination, and pathological findings. MRCP and CT results showed mild dilatation of intrahepatic ducts and increased periductal echogenicity. The eggs were ultimately found in stool by water sedimentation method after the negative report through direct smear. DNA sequencing of PCR production of the eggs demonstrated 98-100% homology with ITS2 of Clonorchis sinensis. After anti-parasite medical treatment, the patient’s symptoms were gradually relieved. Throughout the diagnostic procedure, besides routine examinations, the sedimentation method or concentration method could be used as a sensitive way for both light and heavy C. sinensis infection in the definite diagnosis.

Citations

Citations to this article as recorded by

Research and Discussion on the Clinical Diagnosis Methods of Human Clonorchis sinensis
建锌陈
Hans Journal of Biomedicine.2025; 15(02): 273. CrossRef
Novel mechanism of hepatobiliary system damage and immunoglobulin G4 elevation caused by Clonorchis sinensis infection
Xin-He Zhang, Die Huang, Yi-Ling Li, Bing Chang
World Journal of Clinical Cases.2021; 9(23): 6639. CrossRef
Surgical Infections in Low- and Middle-Income Countries: A Global Assessment of the Burden and Management Needs
Jennifer Rickard, Gregory Beilman, Joseph Forrester, Robert Sawyer, Andrew Stephen, Thomas G. Weiser, Julie Valenzuela
Surgical Infections.2020; 21(6): 478. CrossRef
Clonorchiasis sinensis detected by laparoscopic exploration of biliary tracts in two patients with obstructive jaundice
Xialei Liu, Genglong Zhu, Chaonong Cai, Zhiyue Lv, Jian Li
BMC Infectious Diseases.2019;[Epub] CrossRef
Acute shock caused by Clonorchis sinensis infection: a case report
Nan Wang, Bin Tang, Yuhua Hao, Xue Bai, Xuelin Wang, Yuxiang Li, Yong Yang, Shicun Li, Shuo Hao, Xinyu Wang, Mingyuan Liu, Xiaolei Liu
BMC Infectious Diseases.2019;[Epub] CrossRef

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A case of chronic cerebral paragonimiasis westermani: Shin-Yong Kang, Tae-Kwon Kim, Tae Yun Kim, Young-Il Ha, Sun-Wook Choi, Sung-Jong Hong; Korean J Parasitol 2000;38(3):167-171.
Published online September 30, 2000; DOI: https://doi.org/10.3347/kjp.2000.38.3.167

Abstract
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We report a chronic cerebral paragonimiasis from a 41-year-old Korean man who complains a headache and weakness of left motor neuron components. Magnetic resonance images of the brain revealed conglomerates of multiple ring-like enhancements in temporo-occipital and frontal lobes of the right hemisphere. An intradermal test for paragonimiasis westermani was positive. The patient was born near an endemic area of paragonimiasis and used to eat boiled or grilled freshwater crayfish in his childhood. Nodules in the brain were resected through craniotomies. The eggs of P. westermani were identified pathologically and parasitologically in the calcified necrotic lesions. Examinations on sputum and fecal specimens for the eggs of P. westermani were shown to be negative and a chest radiograph was normal. It is presumed that the brain lesions were formed by P. westermani approximately 30 years ago.

Citations

Citations to this article as recorded by

Imaging of infectious and inflammatory cystic lesions of the brain, a narrative review
Anna Cervantes-Arslanian, Hector H Garcia, Otto Rapalino
Expert Review of Neurotherapeutics.2023; 23(3): 237. CrossRef
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Seok Woo Moon, Taeho Kim
The Korean Journal of Parasitology.2022; 60(5): 353. CrossRef
Inactivation of Paragonimus westermani metacercariae in soy sauce-marinated and frozen freshwater crabs
Tae Im Kim, Se-Ra Oh, Fuhong Dai, Hyun-Jong Yang, Sang-Do Ha, Sung-Jong Hong
Parasitology Research.2017; 116(3): 1003. CrossRef
Cerebral Paragonimiasis Presenting with Sudden Death
Gary W. Procop, Annie Cowell, Sharon L. Reed, Deirdre E. Amaro, Marion J. Tuohy, Jacquelyn Morhaime
The American Journal of Tropical Medicine and Hygiene.2016; 95(6): 1424. CrossRef
Overview of the Effect and Epidemiology of Parasitic Central Nervous System Infections in African Children
Macpherson Mallewa, Jo M. Wilmshurst
Seminars in Pediatric Neurology.2014; 21(1): 19. CrossRef
Cerebral Infarction and Cranial Venous Sinus Thrombosis Caused by Paragonimiasis
Jia‐Yan Wu, Bao‐Rong Zhang, Guo‐Hua Zhao
CNS Neuroscience & Therapeutics.2013; 19(9): 734. CrossRef
The Return of an Old Worm: Cerebral Paragonimiasis Presenting with Intracerebral Hemorrhage
Eun Jung Koh, Seung-Ki Kim, Kyu-Chang Wang, Jong-Yil Chai, Sangjoon Chong, Sung-Hye Park, Jung-Eun Cheon, Ji Hoon Phi
Journal of Korean Medical Science.2012; 27(11): 1428. CrossRef
Excretory–secretory products from Paragonimus westermani increase nitric oxide production in microglia in PKC-dependent and -independent manners
Youngnam Jin, In Young Choi, Chunsook Kim, Suyoung Hong, Won-Ki Kim
Neuroscience Research.2009; 65(2): 141. CrossRef
Update on Eosinophilic Meningoencephalitis and Its Clinical Relevance
Carlos Graeff-Teixeira, Ana Cristina Arámburu da Silva, Kentaro Yoshimura
Clinical Microbiology Reviews.2009; 22(2): 322. CrossRef
Parasitoses et atteinte neurologique
André Paugam
Revue Francophone des Laboratoires.2008; 2008(399): 41. CrossRef
Imaging Manifestations of Tropical Parasitic Infections
Carlos S. Restrepo, Abhijit A. Raut, Roy Riascos, Santiago Martinez, Jorge Carrillo, Srinivasa R. Prasad
Seminars in Roentgenology.2007; 42(1): 37. CrossRef
Excretory-Secretory Products Produced by Paragonimus westermani Differentially Regulate the Nitric Oxide Production and Viability of Microglial Cells
Youngnam Jin, Jae-Chul Lee, In Young Choi, Eun A. Kim, Myeong Heon Shin, Won-Ki Kim
International Archives of Allergy and Immunology.2006; 139(1): 16. CrossRef
Granulomatous Diseases of the Central Nervous System
Antonio José da Rocha, Antonio Carlos Martins Maia, Nelson Paes Diniz Fortes Ferreira, Lázaro Luís Faria do Amaral
Topics in Magnetic Resonance Imaging.2005; 16(2): 155. CrossRef
Paragonimiasis: a view from Columbia
Iván D Vélez, Jorge E Ortega, Luz E Velásquez
Clinics in Chest Medicine.2002; 23(2): 421. CrossRef
Paragonimiasis: a Japanese perspective
Fukumi Nakamura-Uchiyama, Hiroshi Mukae, Yukifumi Nawa
Clinics in Chest Medicine.2002; 23(2): 409. CrossRef