Metabolism of C<sup>14</sup>-glycine by Clonorchis sinensis

, Seong, Soo Hyun; , Seo, Byong Seol

doi:1966.4.2.14

Korean J Parasito > Volume 4(2):1966 > Article

Original Article


Korean J Parasitol. 1966 Dec;4(2):14-22. English. Published online Mar 20, 1994. http://dx.doi.org/10.3347/kjp.1966.4.2.14
Copyright © 1966 by The Korean Society for Parasitology


Metabolism of C¹⁴-glycine by Clonorchis sinensis
Soo Hyun Seong and Byong Seol Seo
Department of Parasitology and Institute of Endemic Diseases, College of Medicine, Seoul National University, Korea.


Abstract
Radioactive C¹⁴-glycine was given to Clonorchis sinensis in Tyrode medium in order to trace the metabolic fate of the labeled carbon. The labeled carbon from glycine enters into every major fraction of Clonorchis sinensis and is highest in the fraction of protein and nucleic acid. Significant amount of C¹⁴-glycine is incorporated into respiratory carbon dioxide. Relatively high percentage of C¹⁴-glycine in medium is converted to amino acid fraction and lipid fraction of the worm. In general, glycine is continuously being utilized in the synthesis of proteins and for energy production despite the uptake rate of glycine decreased gradually as incubation proceeds.

Figures


	Fig. 1 The cumulative curve of C₁₄-glycine which was absorbed by Clonorchis sinensis.


	Fig. 2 The uptake rate of glycine and total respiratory CO₂ production rate in Clonorchis sinensis.


	Fig. 3 The cumulative curves of respiratory CO₂ and relative specific activity of C¹⁴O₂


	Fig. 4 Conversion of C¹⁴-glycine into four major fractions in Clonorchis sinensis.

Tables


	Table 1 The glycine uptake rate and conversion of C¹⁴-glycine into respiratory CO₂


	Table 2 Conversion of C¹⁴-glycine into four major fractions by Clonorchis sinensis

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