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Original Article

Serologic Survey of Toxoplasmosis in Seoul and Jeju-do, and a Brief Review of Its Seroprevalence in Korea

Hyemi Lim1, Sang-Eun Lee2, Bong-Kwang Jung1, Min-Ki Kim1, Mi Youn Lee1, Ho-Woo Nam3, Jong-Gyun Shin4, Cheong-Ha Yun4, Han-Ik Cho4, Eun-Hee Shin1,5, Jong-Yil Chai1
The Korean Journal of Parasitology 2012;50(4):287-293.
Published online: November 26, 2012

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Corresponding author (cjy@snu.ac.kr)
• Received: September 21, 2012   • Revised: October 9, 2012   • Accepted: October 9, 2012

© 2012, Korean Society for Parasitology and Tropical Medicine

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Serologic Survey of Toxoplasmosis in Seoul and Jeju-do, and a Brief Review of Its Seroprevalence in Korea
Korean J Parasitol. 2012;50(4):287-293.   Published online November 26, 2012
DOI: https://doi.org/10.3347/kjp.2012.50.4.287
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Serologic Survey of Toxoplasmosis in Seoul and Jeju-do, and a Brief Review of Its Seroprevalence in Korea
Korean J Parasitol. 2012;50(4):287-293.   Published online November 26, 2012
DOI: https://doi.org/10.3347/kjp.2012.50.4.287
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Serologic Survey of Toxoplasmosis in Seoul and Jeju-do, and a Brief Review of Its Seroprevalence in Korea
Image Image
Fig. 1 Age- and sex-specific seroprevalence of toxoplasmosis among residents in Seoul and Jeju-do assayed by IgG ELISA. The seroprevalence was generally higher in Jeju-do than in Seoul and in males than in females both in Seoul and Jeju-do, although these differences were not statistically significant (P>0.05).
Fig. 2 Chronologic view of the seroprevalence of toxoplasmosis reported in Korea (1982-2012) based on data in Table 4 [7-24]. Each point represents % seropositive rate for each subjected group surveyed. Note that the seroprevalence in recent years (2010-2012) showed an increasing tendency.

Fig. 1

Fig. 2

Serologic Survey of Toxoplasmosis in Seoul and Jeju-do, and a Brief Review of Its Seroprevalence in Korea
District Male
Female
Total
No. examined No. positive (%) No. examined No. positive (%) No. examined No. positive (%) Seoul 426 43 (10.1)b 688 46 (6.7)b 1,114 89 (8.0)d Jeju-do 479 65 (13.6)c 557 52 (9.3)c 1,036 117 (11.3)d Total 905 108 (11.9) 1,245 98 (7.9) 2,150 206 (9.6) Type of occupation Seoul
Jeju-do
Total
No. examined No. ositive (%) No. examined No. positive (%) No. examined No. positive (%) Agriculture 7 0 (0.0) 165 30 (18.2)a 172 30 (17.4) Livestock 1 0 (0.0) 6 0 (0.0) 7 0 (0.0) Fisheries 0 0 (0.0) 8 1 (12.5) 8 1 (12.5) Officeb 207 12 (5.8) 126 8 (6.3) 333 20 (6.0) Housewifec 106 7 (6.6) 76 3 (3.9) 182 10 (5.5) Forestry 6 0 (0.0) 2 1 (50.0) 8 1 (12.5) Mining 2 1 (50.0) 2 0 (0.0) 4 1 (25.0) Services 7 1 (7.1) 35 3 (8.6) 42 4 (9.5) Miscellaneous 778 68 (8.7) 616 71 (11.5) 1,394 139 (10.0) Total 1,114 89 (8.0) 1,036 117 (11.3) 2,150 206 (9.6) Epidemiologic factor Seoul
Jeju-do
Total
No. seropositive (Ta) No. sero-negative No. seropositive (Ta) No. sero-negative No. seropositive (Ta) No. sero-negative Vegetarian diet 11b (21) 255 12 (16) 136 23b (40) 391 No 78b (67) 770 105 (100) 783 183b (166) 1,553 Using bottled water 49 (47) 551 44b (56) 457 93 (105) 1,008 No 40 (41) 474 73b (60) 462 113 (101) 936 Cooked food intake 80 (81) 942 83 (87) 688 163 (172) 1,630 No 9 (7) 83 34 (29) 231 43 (34) 314 Contact with animals 15 (12) 144 28 (21) 166 43 (34) 310 No 74 (76) 881 89 (95) 753 163 (172) 1,634 History of travel abroad 24 (28) 333 50 (54) 430 74 (80) 763 No 65 (60) 692 67 (62) 489 132 (126) 1,181 Authors (year) Subjects Surveyed area No. positive/ No. examined Seropositive rate (%) Assay method Reference Soh et al. (1960) Residents Korea 21/373 5.8 Skin test [6] Choi et al. (1982) Patients in a university hospital Seoul 18/421 4.3 LAa [7] Choi et al. (1983) Mental patients Seoul 11/573 1.9 LA [8] Yoo and Choe (1986) Children ( < 15 years) Seoul 7/120 5.8 Hemag-glutination [9] Choi et al. (1989) Patients in a hospital Seoul 19/1,019 1.9 LA [10] Asthma patients Seoul 11/1,030 1.1 LA Patients in a hospital Jeju-do 45/780 5.8 LA Choi et al. (1992) Neurologic patients Seoul 76/2,016 3.8 LA [11] Neurologic patients Seoul 142/2,016 7.0 ELISA Ryu et al. (1996) Pregnant women Gyeonggi-do 39/899 4.3 ELISA [12] High school students Gyeonggi-do 4/218 1.8 ELISA Kook et al. (1999) Under 10-year children Seoul 42/542 7.7 LA [13] Yang et al. (2000) Students Jeju-do 250/4,570 5.5 ELISA [14] Adults Jeju-do 61/474 12.9 ELISA Hong et al. (2000) High school students Jeju-do 250/4,320 5.5 ELISA [15] Lee et al. (2000) Residents Okcheon-gun 74/1,109 6.9 ELISA [16] Bae et al. (2001) Teachers of childbearing age Jeju-do 12/314 3.8 LA/ELISA [17] Song et al. (2005) Pregnant women Seoul 51/5,725 0.9 ELISA [18] Han et al. (2008) Pregnant women Daejeon 13/351 3.7 ELISA/LA [19] Shin et al. (2009) Patients in a university hospital Daejeon 85/1,265 6.6 LA [20] 84/1,265 6.7 ELISA Ko et al. (2011) Pregnant women Daejeon 19/787 2.4 ELISA [21] Hong et al. (2011) Residents Jeju-do 309/2,348 13.2 ELISA [22] Yang et al. (2012) Residents (2010) Gyeonggi-do 195/1,232 15.8 ELISA [23] Residents (2011) Gyeonggi-do 335/1,296 25.8 ELISA Ahn et al. (2012) Residents Gangwon-do 282/1,661 17.0 ELISA [24] Lim et al. (2012)b Residents Seoul 89/1,114 8.0 ELISA - Residents Jeju-do 117/1,036 11.3 ELISA -
Table 1. Seroprevalencea of Toxoplasma gondii infection among residents in Seoul and Jeju-do

Serum samples were collected and examined during March-September 2011.

b,c,dNo statistically significant differences were found between the paired 2 figures (P>0.05).

Table 2. Seroprevalence of T. gondii infection according to the occupation of subjects in Seoul and Jeju-do

Residents who are engaged in agriculture in Jeju-do showed higher seroprevalence than the average value, although the difference was not statistically significant (P>0.05).

b,cOffice workers and housewives in Seoul or Jeju-do showed lower seroprevalence than the average value; however, the difference was not statistically significant (P>0.05).

Table 3. Relationship of epidemiologic factors and serologic results of T. gondii infection among residents in Seoul and Jeju-do

Theoretical values for the observed ones (no. of seropositive cases).

Statistical significance was noted (P<0.05) between these 2 variables.

Table 4. Comparison of Toxoplasma gondii seropositive rates in Korea reported by different authors

LA; latex agglutination test.

Present study.

Table 1.

Table 2.

Table 3.

Table 4.

PHD : Parasites, Hosts and Diseases

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