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Impact of self-efficacy–based health education programs on behavior modification for Opisthorchis viverrini and cholangiocarcinoma prevention in Thailand: A systematic review and meta-analysis

Worathon Busabong1,2orcid, Somkiattiyos Woradet3,*orcid, Nopparat Songserm1,*orcid
Parasites, Hosts and Diseases 2025;63(1):1-11.
Published online: February 25, 2025

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*Correspondence: (sw, somkiattiyos@tsu.ac.th; ns, nopparat.s@ubru.ac.th)
• Received: October 24, 2024   • Accepted: November 24, 2024

© 2025 The Korean Society for Parasitology and Tropical Medicine

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  • Re: Impact of self-efficacy–based health education programs on behavior modification for Opisthorchis viverrini and cholangiocarcinoma prevention in Thailand: A systematic review and meta-analysis
    Nathkapach Kaewpitoon Rattanapitoon, Chutharat Thanchonnang, Schawanya Kaewpitoon Rattanapitoon
    Parasites, Hosts and Diseases.2025; 63(4): 378.     CrossRef

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Impact of self-efficacy–based health education programs on behavior modification for Opisthorchis viverrini and cholangiocarcinoma prevention in Thailand: A systematic review and meta-analysis
Parasites Hosts Dis. 2025;63(1):1-11.   Published online February 25, 2025
DOI: https://doi.org/10.3347/PHD.24074
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Impact of self-efficacy–based health education programs on behavior modification for Opisthorchis viverrini and cholangiocarcinoma prevention in Thailand: A systematic review and meta-analysis
Parasites Hosts Dis. 2025;63(1):1-11.   Published online February 25, 2025
DOI: https://doi.org/10.3347/PHD.24074
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Impact of self-efficacy–based health education programs on behavior modification for Opisthorchis viverrini and cholangiocarcinoma prevention in Thailand: A systematic review and meta-analysis
Image Image Image Image
Fig. 1 Flowchart of study selection. This figure illustrates the systematic review process, including the initial number of studies identified, the screening phases, and the criteria for exclusion, leading to the final number of studies included in the meta-analysis.
Fig. 2 Risk of bias graph and summary. This figure shows the distribution of the risk of bias judgments across domains, including sequence generation, allocation concealment, blinding, outcome data, reporting, and other biases, categorized by color to indicate low, high, or unclear risk in key bias domains as per the Cochrane Collaboration tool.
Fig. 3 The forest plot and funnel plot present the effects of health education programs on outcomes, respectively: (A), (a) knowledge; (B), (b) self-efficacy; and (C), (c) behavior modification for preventing Opisthorchis viverrini and cholangiocarcinoma before and after the experiment. IV, inverse variance; CI, confidence interval.
Fig. 4 The forest plot and funnel plot present the effects of health education programs on outcomes, respectively: (A), (a) knowledge; (B), (b) self-efficacy; and (C), (c) behavior modification for preventing Opisthorchis viverrini and cholangiocarcinoma between the experimental and comparison groups. IV, inverse variance; CI, confidence interval.

Fig. 1

Fig. 2

Fig. 3

Fig. 4

Impact of self-efficacy–based health education programs on behavior modification for Opisthorchis viverrini and cholangiocarcinoma prevention in Thailand: A systematic review and meta-analysis

Literature reviews of health education programs for preventing Opisthorchis viverrini and cholangiocarcinoma in Thailand

Reference Age group (year) Intervention Comparison Results
n Mean SD n Mean SD
Knowledge
 [9] 10–12 47 10.91 1.96 47 7.85 1.83 After the experiment, the intervention group had higher knowledge than the comparison group (P<0.001).
 [10] 15–70 35 13.10 1.80 35 10.90 1.60 The experimental group had a mean knowledge score higher than the comparison group (mean difference=2.5, 95% CI=1.4–3.6, P<0.001).
 [11] 20–50 30 11.87 1.01 30 8.53 1.89 After the trial, the family leaders had mean knowledge scores higher than the comparison group (P<0.001).
 [15] 40–59 40 8.72 1.33 40 7.02 1.34 The experimental group’s mean knowledge scores were significantly higher than the comparison group (P<0.05).
 [12] 10–12 35 11.83 1.07 35 8.97 2.26 After the intervention, the experimental group’s knowledge scores were higher than the comparison group (P<0.001).
 [7] 30–89 33 19.42 0.61 33 15.79 1.72 The experimental group had significantly greater knowledge than the comparison group (P<0.05).
 [16] 10–12 113 7.60 2.70 113 3.60 1.90 The intervention group had significantly greater knowledge than those in the comparison schools (P<0.05).
 [17] ≥ 30 38 11.66 2.16 38 9.42 2.09 The experimental group knew significantly higher than the comparison group (P<0.05).
 [6] ≥ 20 34 14.30 2.10 34 12.70 1.60 After the experiment, the mean scores of knowledge of the experimental group were significantly higher than before the comparison group (P<0.05).
Self-efficacy
 [12] 10–12 35 28.26 1.70 35 23.83 3.44 After the intervention, the experimental group’s perceived self-efficacy scores were higher than the comparison group (P<0.001).
 [7] 30–89 33 2.82 0.39 33 2.57 0.51 The experimental group had significantly greater self-efficacy than the comparison group (P<0.05).
 [13] 20–60 54 41.13 4.90 54 31.63 4.66 After participating in the program, the experimental group perceived self-efficacy more than the comparison group (P<0.05).
 [16] 10–12 113 9.70 1.70 113 8.30 1.60 The pupils in the intervention group had significantly greater self-efficacy than those in the comparison schools (P<0.05).
 [6] ≥ 20 34 3.80 0.40 34 3.20 0.80 After the experiment, the experimental group’s perceived self-efficacy scores were significantly higher than the comparison group (P<0.05).
Behavior/practice/outcome expectation
 [9] 10–12 47 28.85 2.90 47 25.77 2.71 The experimental group’s mean practice scores were significantly higher than the comparison group (P<0.001).
 [10] 15–70 35 23.10 1.40 35 19.10 1.70 The experimental group had a mean practice score higher than the comparison group (mean difference=4.4, 95% CI=4.2–7.9, P<0.001).
 [11] 20–50 30 2.47 0.14 30 1.75 0.24 The family leaders’ mean behavior scores increased than those of the comparison group (P<0.001).
 [15] 40–59 40 59.40 8.57 40 41.35 6.10 The experimental group had a mean score of practice more than the comparison groups (P<0.05).
 [18] ≥ 60 22 70.36 6.48 22 64.00 7.40 The experimental group’s mean score of complications-preventing behaviors was significantly higher than the comparison group (P<0.05).
 [12] 10–12 35 20.60 0.55 35 18.60 2.15 After the intervention, the scores of practice of the experimental group were higher than the comparison group (P<0.001).
 [7] 30–89 33 2.52 0.51 33 2.24 0.43 The experimental group had significantly greater practice than the comparison group (P<0.05).
 [13] 20–60 54 44.99 4.42 54 36.08 6.14 After the program, the experimental group had better practice than the comparison group (P<0.05).
 [17] ≥ 30 38 36.00 4.62 38 32.26 4.39 The experimental group had proper behaviors to prevent the diseases higher than the comparison group (P<0.05).
 [6] ≥ 20 34 2.30 0.40 34 1.70 0.50 The experimental group’s mean scores of prevention behavior were significantly higher than before the comparison group (P<0.05).
 [19] ≥ 20 47 29.68 2.34 47 23.29 2.30 The mean social support score for the prevention behavior of the experimental group was significantly higher than that of the comparison group (P<0.001).
 [14] ≥ 20 150 34.23 2.18 150 28.63 1.82 The experimental group’s mean scores of correct behaviors were significantly higher than those of the comparison group (P<0.05).

CI, confidence interval.

Table 1 Literature reviews of health education programs for preventing Opisthorchis viverrini and cholangiocarcinoma in Thailand

CI, confidence interval.

Table 1

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