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Volume 51(1); February 2013

Articles from Symposium on Asian Taenia (October 2011, Osong, Korea)s

Molecular Approaches to Taenia asiatica
Hyeong-Kyu Jeon, Keeseon S. Eom
Korean J Parasitol 2013;51(1):1-8.
Published online February 18, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.1.1

Taenia solium, T. saginata, and T. asiatica are taeniid tapeworms that cause taeniasis in humans and cysticercosis in intermediate host animals. Taeniases remain an important public health concerns in the world. Molecular diagnostic methods using PCR assays have been developed for rapid and accurate detection of human infecting taeniid tapeworms, including the use of sequence-specific DNA probes, PCR-RFLP, and multiplex PCR. More recently, DNA diagnosis using PCR based on histopathological specimens such as 10% formalin-fixed paraffin-embedded and stained sections mounted on slides has been applied to cestode infections. The mitochondrial gene sequence is believed to be a very useful molecular marker for not only studying evolutionary relationships among distantly related taxa, but also for investigating the phylo-biogeography of closely related species. The complete sequence of the human Taenia tapeworms mitochondrial genomes were determined, and its organization and structure were compared to other human-tropic Taenia tapeworms for which complete mitochondrial sequence data were available. The multiplex PCR assay with the Ta4978F, Ts5058F, Tso7421F, and Rev7915 primers will be useful for differential diagnosis, molecular characterization, and epidemiological surveys of human Taenia tapeworms.

Citations

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  • Identification and functional characterization of the siRNA pathway in Taenia crassiceps by silencing Enolase A
    Julio Guerrero-Hernández, Raúl J. Bobes, Martín García-Varela, Alejandro Castellanos-Gonzalez, Juan P. Laclette
    Acta Tropica.2022; 225: 106197.     CrossRef
  • Taenia saginata Infection Misdiagnosed as Acute Cholecystitis in a Tibetan Patient, in China
    Xiu-Min Han, Xue-Yong Zhang, Ying-Na Jian, Qing-Shan Tian
    The Korean Journal of Parasitology.2021; 59(3): 311.     CrossRef
  • Current status of Opisthorchis viverrini, minute intestinal fluke and Taenia spp. infections among inhabitants in the Kenethao district of northern Lao PDR
    Phasouk Senephansiri, Thaksaporn Thongseesuksai, Phaviny Sithay, Sakhone Laymanivong, Thidarut Boonmar, Porntip Laummaunwai
    Transactions of The Royal Society of Tropical Medicine and Hygiene.2020; 114(5): 397.     CrossRef
  • Recent advances in nucleic acid-based methods for detection of helminth infections and the perspective of biosensors for future development
    Hanif Ullah, Abdul Qadeer, Muhammad Rashid, Muhammad Imran Rashid, Guofeng Cheng
    Parasitology.2020; 147(4): 383.     CrossRef
  • Mitochondrial Genome Sequences of <i>Spirometra erinaceieuropaei</i> and <i>S. decipiens</i> (Cestoidea: Diphyllobothriidae)
    Keeseon S. Eom, Hansol Park, Dongmin Lee, Seongjun Choe, Kyu-Heon Kim, Hyeong-Kyu Jeon
    The Korean Journal of Parasitology.2015; 53(4): 455.     CrossRef
  • Methods for Quantification of Soil-Transmitted Helminths in Environmental Media: Current Techniques and Recent Advances
    Philip A. Collender, Amy E. Kirby, David G. Addiss, Matthew C. Freeman, Justin V. Remais
    Trends in Parasitology.2015; 31(12): 625.     CrossRef
  • Rapid Molecular Identification of Human Taeniid Cestodes by Pyrosequencing Approach
    Tongjit Thanchomnang, Chairat Tantrawatpan, Pewpan M. Intapan, Oranuch Sanpool, Penchom Janwan, Viraphong Lulitanond, Somjintana Tourtip, Hiroshi Yamasaki, Wanchai Maleewong, Emmanuel Dias-Neto
    PLoS ONE.2014; 9(6): e100611.     CrossRef
  • Control of cysticercosis in Madagascar: beware of the pitfalls
    Harentsoaniaina Rasamoelina-Andriamanivo, Vincent Porphyre, Ronan Jambou
    Trends in Parasitology.2013; 29(11): 538.     CrossRef
  • 11,944 View
  • 119 Download
  • Crossref
Human Taeniasis in the Republic of Korea: Hidden or Gone?
Jong-Yil Chai
Korean J Parasitol 2013;51(1):9-17.
Published online February 18, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.1.9

History and current status of human taeniasis in the Republic of Korea, due to Taenia solium, Taenia asiatica, and Taenia saginata, are briefly reviewed. Until the 1980s, human taeniasis had been quite common in various localities of Korea. A study from 1924 reported 12.0% egg prevalence in fecal examinations. Thereafter, the prevalence of Taenia spp. ranged from 3% to 14% depending on the time and locality. Jeju-do, where pigs were reared in a conventional way, was the highest endemic area of taeniasis. An analysis of internal transcribed spacer 2 and mitochondrial cytochrome c oxidase 1 genes of 68 taeniasis cases reported from 1935 to 2005 in Korea by a research group revealed the relative occurrence of the 3 Taenia spp. as follows: T. solium (4.4%), T. asiatica (75.0%), and T. saginata (20.6%). However, national surveys on intestinal helminths conducted every 5 years on randomly selected people revealed that the Taenia egg prevalence dropped from 1.9% in 1971 to 0.02% in 1997 and finally to 0.0% in 2004. With the exception of 3 egg-positive cases reported in 2008 and 2 worm-proven cases in 2011, no more cases have been officially recorded. Based on these surveys and also on other literature, it can be concluded that taeniasis has virtually disappeared from Korea, although a few sporadic cases may remain hidden. Human cysticercosis is also expected to disappear within a couple of decades in Korea.

Citations

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  • One Health approach for prioritization of potential foodborne pathogens: Risk‐ranking, Delphi survey, and criteria evaluation pre‐ and post‐COVID‐19 pandemic
    Sun Min Park, Changsun Choi, Min Suk Rhee
    Comprehensive Reviews in Food Science and Food Safety.2024;[Epub]     CrossRef
  • Occurrence of a Hybrid Between Taenia saginata and Taenia asiatica Tapeworms in Cambodia
    Taehee Chang, Bong-Kwang Jung, Sooji Hong, Hyejoo Shin, Seungwan Ryoo, Jeonggyu Lee, Keon Hoon Lee, Hansol Park, Keeseon S. Eom, Virak Khieu, Rekol Huy, Woon-Mok Sohn, Jong-Yil Chai
    The Korean Journal of Parasitology.2021; 59(2): 179.     CrossRef
  • Disseminated Septic Lesions Caused by Staphylococcus epidermidis Mimicking Cysticercosis Detected on Ultrasonography in a Pediatric Patient with Acute Myeloid Leukemia
    Jae Min Lee, Joon-Sik Choi, Keon Hee Yoo, Yae-Jean Kim, Sun-Ja Kim
    Pediatric Infection & Vaccine.2020; 27(2): 134.     CrossRef
  • A co-infection case report of Taenia saginata in a patient with subclinical clonorchiasis confirmed by the combination of diagnostic tools
    Ju Hyeon Shin, Eun Jeong Won, Jee Seung Jung, Kyung-Hwa Park, Kwang Il Nam, Soo Hyun Kim, Jong Hee Shin
    BMC Infectious Diseases.2019;[Epub]     CrossRef
  • Taeniasis and cysticercosis in Asia: A review with emphasis on molecular approaches and local lifestyles
    Akira Ito, Tiaoying Li, Toni Wandra, Paron Dekumyoy, Tetsuya Yanagida, Munehiro Okamoto, Christine M Budke
    Acta Tropica.2019; 198: 105075.     CrossRef
  • Four Taeniasis saginata Cases Diagnosed at a University Hospital in Korea
    Eun Jeong Won, Ju Hyeon Shin, Yu Jeong Lee, Moon-Ju Kim, Seung Ji Kang, Sook In Jung, Soo Hyun Kim, Jong Hee Shin, Jong-Yil Chai, Sung-Shik Shin
    The Korean Journal of Parasitology.2019; 57(3): 313.     CrossRef
  • Neurocysticercosis: Clinical Characteristics and Changes from 26 Years of Experience in an University Hospital in Korea
    Hyo-Ju Son, Min Jae Kim, Kyung Hwa Jung, Sungim Choi, Jiwon Jung, Yong Pil Chong, Sung-Han Kim, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Jun Hee Woo, Bong-Kwang Jung, Hyemi Song, Jong-Yil Chai
    The Korean Journal of Parasitology.2019; 57(3): 265.     CrossRef
  • Ten Cases of Taenia saginata Infection Confirmed by Analysis of the Internal Transcribed Spacer 1 rDNA Region in the Republic of Korea
    Su-Min Song, Hae Soo Yun, Dorene VanBik, Hyun-Ha Chang, Sang-Ah Lee, Shin-Woo Kim, Namhee Ryoo, Dong Yeub Eun, Nan Young Lee, Youn-Kyoung Goo, Yeonchul Hong, Meesun Ock, Hee-Jae Cha, Dong-Il Chung
    The Korean Journal of Parasitology.2019; 57(4): 417.     CrossRef
  • A Case of Imported Taenia asiatica Infection in Japan
    Hiroki Namikawa, Yasuhiko Takemoto, Ikuji Shimazaki, Ayako Makuuchi, Masanori Kobayashi, Shigeki Kinuhata, Koichi Yamada, Hiroki Fujimoto, Hiromitsu Toyoda, Noriko Kamata, Yoshihiro Tochino, Isao Teramoto, Niichiro Abe, Mina Morimura, Hiroshi Kakeya, Taic
    Japanese Journal of Infectious Diseases.2018; 71(2): 170.     CrossRef
  • Molecular Diagnosis of Taenia saginata Tapeworm Infection in 2 Schoolchildren, Myanmar
    Eun Jeong Won, Bong-Kwang Jung, Hyemi Song, Mi-Seon Kim, Hyun-Seung Kim, Keon Hoon Lee, Min-Jae Kim, Myung Geun Shin, Jong Hee Shin, Soon-Pal Suh, Sung-Jong Hong, Woon-Mok Sohn, Thi Thi Htoon, Htay Htay Tin, Jong-Yil Chai
    Emerging Infectious Diseases.2018; 24(6): 1156.     CrossRef
  • Porcine cysticercosis (Taenia solium and Taenia asiatica): mapping occurrence and areas potentially at risk in East and Southeast Asia
    Uffe Christian Braae, Nguyen Manh Hung, Fadjar Satrija, Virak Khieu, Xiao-Nong Zhou, Arve Lee Willingham
    Parasites & Vectors.2018;[Epub]     CrossRef
  • Cysticercosis/taeniasis endemicity in Southeast Asia: Current status and control measures
    Hai-Wei Wu, Akira Ito, Lin Ai, Xiao-Nong Zhou, Luz P. Acosta, Arve Lee Willingham III
    Acta Tropica.2017; 165: 121.     CrossRef
  • Four Cases of Taenia saginata Infection with an Analysis of COX1 Gene
    Jaeeun Cho, Bong-Kwang Jung, Hyemi Lim, Min-Jae Kim, Thanapon Yooyen, Dongmin Lee, Keeseon S. Eom, Eun-Hee Shin, Jong-Yil Chai
    The Korean Journal of Parasitology.2014; 52(1): 79.     CrossRef
  • Epidemiology and genetic diversity of Taenia asiatica: a systematic review
    Anita Ale, Bjorn Victor, Nicolas Praet, Sarah Gabriël, Niko Speybroeck, Pierre Dorny, Brecht Devleesschauwer
    Parasites & Vectors.2014;[Epub]     CrossRef
  • Clinical Update on Parasitic Diseases
    Min Seo
    Korean Journal of Medicine.2013; 85(5): 469.     CrossRef
  • 13,346 View
  • 140 Download
  • Crossref
Current Status and Perspectives of Cysticercosis and Taeniasis in Japan
Hiroshi Yamasaki
Korean J Parasitol 2013;51(1):19-29.
Published online February 18, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.1.19

This mini-review describes recent epidemiological trends in cysticercosis and taeniasis in Japan. Some of the topics discussed herein were presented at the first symposium on "Current perspectives of Taenia asiatica researches", that was held in Osong in Chungbuk Province, South Korea, in October 2011 and organized by Prof. K. S. Eom, Chungbuk National University School of Medicine. To better understand the trends in the occurrence of cysticercosis and taeniasis in Japan, clinical cases reported in 2005 have been updated. In addition, the current status of Taenia asiatica infections successively occurring in Japan since 2010 is also discussed.

Citations

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  • Taenia asiatica: Mitochondrial signatures based analysis of an emerging public health threat in India
    Aman D. Moudgil, Anil K. Nehra, Pallavi Moudgil
    New Microbes and New Infections.2025; 63: 101562.     CrossRef
  • Phylogenetic characterization of the pork tapeworm Taenia solium in Japan: implications for the enigmatic evolutionary history
    Naoki Hayashi, Ryo Kuwamoto, Mitsuhiro Okada, Kenta Suzuki, Takaya Hoketsu, Samuel Kelava, Yuma Ohari, Munehiro Okamoto, Kinpei Yagi, Nariaki Nonaka, Ryo Nakao
    International Journal for Parasitology.2025; 55(10): 497.     CrossRef
  • Successful Gastrografin Vermifugation for Taenia saginata-associated Appendicitis
    Keigo Kobayashi, Yasuhiro Umekawa
    Internal Medicine.2024; 63(23): 3185.     CrossRef
  • Development and evaluation of an immunochromatography-based point-of-care test kit for a rapid diagnosis of human cysticercosis
    Lakkhana Sadaow, Patcharaporn Boonroumkaew, Rutchanee Rodpai, Penchom Janwan, Oranuch Sanpool, Tongjit Thanchomnang, Yasuyuki Morishima, Marcello Otake Sato, Yasuhito Sako, Kaoru Kobayashi, Misako Iwai, Wanchai Maleewong, Hiroshi Yamasaki, Pewpan M. Intap
    Food and Waterborne Parasitology.2023; 33: e00211.     CrossRef
  • Current situation of human Taenia asiatica taeniosis in Japan
    Hiroshi Yamasaki, Yasuyuki Morishima, Hiromu Sugiyama, Munehiro Okamoto
    Parasitology International.2021; 83: 102340.     CrossRef
  • Epidemiology of Taenia saginata taeniosis/cysticercosis: a systematic review of the distribution in East, Southeast and South Asia
    Ramon M. Eichenberger, Lian F. Thomas, Sarah Gabriël, Branco Bobić, Brecht Devleesschauwer, Lucy J. Robertson, Anastasios Saratsis, Paul R. Torgerson, Uffe C. Braae, Veronique Dermauw, Pierre Dorny
    Parasites & Vectors.2020;[Epub]     CrossRef
  • Possible Reintroduction of Taenia asiatica in the Kanto Region of Japan
    Daisuke Taniyama, Izumi Inoue, Megumi Kawano, Chiaki Arakawa, Tomohide Adachi, Yasuyuki Morishima, Hiroshi Yamasaki, Hiromu Sugiyama
    Japanese Journal of Infectious Diseases.2019; 72(1): 62.     CrossRef
  • Taeniasis and cysticercosis in Asia: A review with emphasis on molecular approaches and local lifestyles
    Akira Ito, Tiaoying Li, Toni Wandra, Paron Dekumyoy, Tetsuya Yanagida, Munehiro Okamoto, Christine M Budke
    Acta Tropica.2019; 198: 105075.     CrossRef
  • Clinical characteristics and epidemiology of intestinal tapeworm infections over the last decade in Tokyo, Japan: A retrospective review
    Motoyuki Tsuboi, Kayoko Hayakawa, Hiroshi Yamasaki, Yuichi Katanami, Kei Yamamoto, Satoshi Kutsuna, Nozomi Takeshita, Shuzo Kanagawa, Norio Ohmagari, Yasuyuki Kato, Pablo Maravilla
    PLOS Neglected Tropical Diseases.2018; 12(2): e0006297.     CrossRef
  • A Case of Imported Taenia asiatica Infection in Japan
    Hiroki Namikawa, Yasuhiko Takemoto, Ikuji Shimazaki, Ayako Makuuchi, Masanori Kobayashi, Shigeki Kinuhata, Koichi Yamada, Hiroki Fujimoto, Hiromitsu Toyoda, Noriko Kamata, Yoshihiro Tochino, Isao Teramoto, Niichiro Abe, Mina Morimura, Hiroshi Kakeya, Taic
    Japanese Journal of Infectious Diseases.2018; 71(2): 170.     CrossRef
  • Epidemiology ofDiphyllobothrium nihonkaienseDiphyllobothriasis, Japan, 2001–2016
    Hiroshi Ikuno, Shinkichi Akao, Hiroshi Yamasaki
    Emerging Infectious Diseases.2018;[Epub]     CrossRef
  • Cysticercosis/taeniasis endemicity in Southeast Asia: Current status and control measures
    Hai-Wei Wu, Akira Ito, Lin Ai, Xiao-Nong Zhou, Luz P. Acosta, Arve Lee Willingham III
    Acta Tropica.2017; 165: 121.     CrossRef
  • Multiplex real-time PCR monitoring of intestinal helminths in humans reveals widespread polyparasitism in Northern Samar, the Philippines
    Catherine A. Gordon, Donald P. McManus, Luz P. Acosta, Remigio M. Olveda, Gail M. Williams, Allen G. Ross, Darren J. Gray, Geoffrey N. Gobert
    International Journal for Parasitology.2015; 45(7): 477.     CrossRef
  • Culinary delights and travel? A review of zoonotic cestodiases and metacestodiases
    Akira Ito, Christine M. Budke
    Travel Medicine and Infectious Disease.2014; 12(6): 582.     CrossRef
  • Epidemiology and genetic diversity of Taenia asiatica: a systematic review
    Anita Ale, Bjorn Victor, Nicolas Praet, Sarah Gabriël, Niko Speybroeck, Pierre Dorny, Brecht Devleesschauwer
    Parasites & Vectors.2014;[Epub]     CrossRef
  • Rapid Molecular Identification of Human Taeniid Cestodes by Pyrosequencing Approach
    Tongjit Thanchomnang, Chairat Tantrawatpan, Pewpan M. Intapan, Oranuch Sanpool, Penchom Janwan, Viraphong Lulitanond, Somjintana Tourtip, Hiroshi Yamasaki, Wanchai Maleewong, Emmanuel Dias-Neto
    PLoS ONE.2014; 9(6): e100611.     CrossRef
  • Priorities for research and control of cestode zoonoses in Asia
    Ning Xiao, Jia-Wen Yao, Wei Ding, Patrick Giraudoux, Philip S Craig, Akira Ito
    Infectious Diseases of Poverty.2013;[Epub]     CrossRef
  • Nothing is perfect! Trouble-shooting in immunological and molecular studies of cestode infections
    AKIRA ITO
    Parasitology.2013; 140(13): 1551.     CrossRef
  • 14,541 View
  • 131 Download
  • Crossref
Historical Overview of Taenia asiatica in Taiwan
Hong Kean Ooi, Chau-Mei Ho, Wen-Cheng Chung
Korean J Parasitol 2013;51(1):31-36.
Published online February 18, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.1.31

An overview of the epidemiological, biological, and clinical studies of Taenia and taeniasis in Taiwan for the past century is presented. The phenomenal observations that led to the discovery of Taenia asiatica as a new species, which differ from Taenia solium and Taenia saginata, are described. Parasitological surveys of the aborigines in Taiwan revealed a high prevalence of taeniasis, which might be due to the culture of eating raw liver of hunted wild boars. Chemotherapeutic deworming trials involving many patients with taeniasis were discussed. Praziquantel was found to be very effective, but sometimes complete worms could not be recovered from the feces after treatment, probably due to the dissolution of the proglottids. Atabrine, despite some side effects, can still be used, in properly controlled dosages, as the drug of choice for human T. asiatica infection if we need to recover the expelled worms for morphological examinations. Research results on the infection of T. asiatica eggs from Taiwan aborigines in experimental animals were also noted. Since the pig serve as the natural intermediate host of T. asiatica and the predilection site is the liver, a differential comparison of other parasitic pathogens that might cause apparently similar lesions is also presented.

Citations

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  • Taenia asiatica: Mitochondrial signatures based analysis of an emerging public health threat in India
    Aman D. Moudgil, Anil K. Nehra, Pallavi Moudgil
    New Microbes and New Infections.2025; 63: 101562.     CrossRef
  • Teniases caused by Taenia asiatica, Taenia saginata, Taenia solium
    S. B. Chuelov, A. L. Rossina
    CHILDREN INFECTIONS.2021; 20(4): 42.     CrossRef
  • Accurate diagnosis of lesions suspected of being caused by Taenia solium in body organs of pigs with naturally acquired porcine cysticercosis
    Charles G. Gauci, Chrisostom Ayebazibwe, Zachary Nsadha, Chris Rutebarika, Ishab Poudel, Keshav Sah, Dinesh Kumar Singh, Andrew Stent, Angela Colston, Meritxell Donadeu, Marshall W. Lightowlers, Mar Siles-Lucas
    PLOS Neglected Tropical Diseases.2019; 13(6): e0007408.     CrossRef
  • Epidemiology and genetic diversity of Taenia asiatica: a systematic review
    Anita Ale, Bjorn Victor, Nicolas Praet, Sarah Gabriël, Niko Speybroeck, Pierre Dorny, Brecht Devleesschauwer
    Parasites & Vectors.2014;[Epub]     CrossRef
  • Parasitic porkborne hazards, globalisation, and meat inspection
    Maria Teresa Galán-Puchades, Màrius V. Fuentes
    Food Control.2014; 46: 546.     CrossRef
  • 13,969 View
  • 117 Download
  • Crossref
Current Status of Taeniasis in Thailand
Malinee Thairungroj Anantaphruti
Korean J Parasitol 2013;51(1):37-42.
Published online February 18, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.1.37

Taeniasis is prevalent in all regions of Thailand, except the South. Infections were more frequently found in males than females of any age from 7-83 years. Taenia saginata is the most common species throughout the country. Taenia asiatica was reported only in the province of Kanchanaburi in the Central region. Co-infections, with Taenia solium and T. asiatica or T. solium and T. saginata, were found. Hybridization between T. asiatica and T. saginata is evidence that co-infection is never found between these 2 species. Finding more than 1 worm in a single patient was not entirely rare. Genetic variation was found without correlation to its geographic distribution in T. saginata, whereas no variation was found in T. asiatica.

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  • Nationwide spatial dynamics of taeniasis in Thailand: declining prevalence but shifting focus and One Health risk factors across 2008–2014
    Pornphutthachat Sota, Kefyalew Addis Alene, Thitima Wongsaroj, Sirikachorn Tangkawattana, Archie C. A. Clements, Banchob Sripa
    Parasites & Vectors.2025;[Epub]     CrossRef
  • Assessment of knowledge and practices regarding taeniasis and cysticercosis in Pak Chong, Nakhon Ratchasima, Thailand: A cross-sectional study
    Wuttipong Phumrattanaprapin, Nitima Tatiya-apiradee, Pattana Jantaban, Wiriya Mahikul, Gideon Zulu
    PLOS ONE.2024; 19(7): e0307240.     CrossRef
  • Current prevalence and geographic distribution of helminth infections in the parasitic endemic areas of rural Northeastern Thailand
    Pongsakorn Martviset, Wansika Phadungsil, Kesara Na-Bangchang, Wiwat Sungkhabut, Tanutchamon Panupornpong, Parisa Prathaphan, Nattaya Torungkitmangmi, Salisa Chaimon, Chompunoot Wangboon, Mantana Jamklang, Sirilak Chumkiew, Pichanee Watthanasiri, Amornrat
    BMC Public Health.2023;[Epub]     CrossRef
  • A retrospective study of Taenia spp. in Cuban patients: what does molecular analysis tell us?
    Luis Enrique Jerez Puebla, Fidel A. Núñez Fernández, Jorge Fraga Nodarse, Raul Cordovi Prado, Iraís Atencio Millán, Iredys Cruz Rodríguez, Rigoberto Fimia Duarte, Marina del Carmen Sánchez Romero, Sahily de la Caridad Ortega Medina, Ubaldo del Risco, Liss
    Food and Waterborne Parasitology.2021; 25: e00136.     CrossRef
  • Epidemiology of Taenia saginata taeniosis/cysticercosis: a systematic review of the distribution in East, Southeast and South Asia
    Ramon M. Eichenberger, Lian F. Thomas, Sarah Gabriël, Branco Bobić, Brecht Devleesschauwer, Lucy J. Robertson, Anastasios Saratsis, Paul R. Torgerson, Uffe C. Braae, Veronique Dermauw, Pierre Dorny
    Parasites & Vectors.2020;[Epub]     CrossRef
  • Taeniasis and cysticercosis in Asia: A review with emphasis on molecular approaches and local lifestyles
    Akira Ito, Tiaoying Li, Toni Wandra, Paron Dekumyoy, Tetsuya Yanagida, Munehiro Okamoto, Christine M Budke
    Acta Tropica.2019; 198: 105075.     CrossRef
  • Comment on “Epidemiological Survey on Porcine Cysticercosis in Nay Pyi Taw Area, Myanmar”
    Maria Teresa Galán-Puchades, Màrius Vicent Fuentes
    Journal of Veterinary Medicine.2016; 2016: 1.     CrossRef
  • Epidemiology and genetic diversity of Taenia asiatica: a systematic review
    Anita Ale, Bjorn Victor, Nicolas Praet, Sarah Gabriël, Niko Speybroeck, Pierre Dorny, Brecht Devleesschauwer
    Parasites & Vectors.2014;[Epub]     CrossRef
  • Current Status of Taeniasis in Thailand
    Malinee Thairungroj Anantaphruti
    The Korean Journal of Parasitology.2013; 51(1): 37.     CrossRef
  • Genetic Diversity of Taenia asiatica from Thailand and Other Geographical Locations as Revealed by Cytochrome c Oxidase Subunit 1 Sequences
    Malinee Thairungroj Anantaphruti, Urusa Thaenkham, Dorn Watthanakulpanich, Orawan Phuphisut, Wanna Maipanich, Tippayarat Yoonuan, Supaporn Nuamtanong, Somjit Pubampen, Surapol Sanguankiat
    The Korean Journal of Parasitology.2013; 51(1): 55.     CrossRef
  • 10,338 View
  • 83 Download
  • Crossref
State of the Art of Taenia solium as Compared to Taenia asiatica
Ana Flisser
Korean J Parasitol 2013;51(1):43-49.
Published online February 18, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.1.43

Three species of tapeworms infect humans in their adult stage (Taenia solium, Taenia saginata and Taenia asiatica). The 3 are flat, opaque white or yellowish, and exceptional long segmented parasites, measuring 1 to 12 m in their adult stage. In this review, the development of the knowledge regarding the first species, mainly focused on understanding how the larval stage or cysticercus is transmitted to humans, is described. The second species is a cosmopolitan parasite that only causes taeniosis and not cysticercosis; therefore, it will not be included. Information on the third species, which is presently being produced, since this species was recognized as such only at the end of the 20th century, will be discussed at the end of this review.

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    Scientific Data.2025;[Epub]     CrossRef
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    Justine Daudi Maganira, Noel Mark Makwinya, Beda John Mwang'onde
    Parasite Epidemiology and Control.2025; 30: e00445.     CrossRef
  • Baseline Assessment of Taeniasis and Cysticercosis Infections in a High-Priority Region for Taenia solium Control in Colombia
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    Pathogens.2025; 14(8): 755.     CrossRef
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    Fela Mendlovic, Agnes Fleury, Ana Flisser
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    Carolina Guzman, Hector H Garcia
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  • Challenges Encountered When Evaluating an Antibody-Detecting Point-of-Care Test for Taeniosis in an Endemic Community in Zambia: A Prospective Diagnostic Accuracy Study
    Chishimba Mubanga, Chiara Trevisan, Inge Van Damme, Veronika Schmidt, Isaac K. Phiri, Gideon Zulu, John Noh, Sukwan Handali, Richard Mambo, Mwelwa Chembensofu, Maxwell Masuku, Dries Reynders, Famke Jansen, Emmanuel Bottieau, Pascal Magnussen, Andrea S. Wi
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  • Diagnosis of Taenia solium infections based on “mail order” RNA-sequencing of single tapeworm egg isolates from stool samples
    Henrik Sadlowski, Veronika Schmidt, Jonathan Hiss, Johannes A. Kuehn, Christian G. Schneider, Gideon Zulu, Alex Hachangu, Chummy S. Sikasunge, Kabemba E. Mwape, Andrea S. Winkler, Markus Schuelke, Xiao-Nong Zhou
    PLOS Neglected Tropical Diseases.2021; 15(12): e0009787.     CrossRef
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  • Mapping the residual incidence of taeniasis and cysticercosis in Colombia, 2009–2013, using geographical information systems: Implications for public health and travel medicine
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    Dolores A. Ayón-Núñez, Gladis Fragoso, Clara Espitia, Martín García-Varela, Xavier Soberón, Gabriela Rosas, Juan P. Laclette, Raúl J. Bobes
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    Ana Vargas-Calla, Luis A. Gomez-Puerta, Juan Calcina, Omar Gonzales-Viera, Cesar Gavidia, Maria T. Lopez-Urbina, Hector H. Garcia, Armando E. Gonzalez
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Taenia asiatica: the Most Neglected Human Taenia and the Possibility of Cysticercosis
M. Teresa Gal?n-Puchades, Mario V. Fuentes
Korean J Parasitol 2013;51(1):51-54.
Published online February 18, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.1.51

Not only Taenia solium and Taenia saginata, but also Taenia asiatica infects humans. The last species is not included in the evaluation of the specificity of the immunodiagnostic techniques for taeniasis/cysticercosis. There is currently no specific immunodiagnostic method for T. asiatica available. Therefore, due to the fact that molecular techniques (the only tool to distinguish the 3 Taenia species) are normally not employed in routine diagnostic methods, the 2 questions concerning T. asiatica (its definite geographic distribution and its ability to cause human cysticercosis), remain open, turning T. asiatica into the most neglected agent of human taeniasis-cysticercosis.

Citations

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  • On the etiology of a case of human liver cysticercosis in India
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  • Potential of Aframomum melegueta and Xylopia aethiopica Against Taenia spp.: Plant-Based Remedies as Novel Anthelmintics
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  • Novel Oral papaya-based preventive and therapeutic vaccine for controlling different zoonotic Taeniid parasites: Current advances
    Marisela Hernández, Anabel Ortiz Caltempa, Nelly Villalobos, María Celina Elisondo, Cynthia Guzmán, Juan A. Hernández-Aceves, Liliana Aguilar, Ivan Flores-Pérez, José Juan Martínez, Sahara D. Elguea Zarate, Maria Jesús Perteguer Prieto, Gabriela Meneses,
    Vaccine.2025; 66: 127818.     CrossRef
  • Edukasi tentang Deteksi Dini, Pengobatan, dan Pencegahan Kejadian Taeniasis oleh Taenia asiatica di Desa Negeri Dolok, Kecamatan Silau Kahean, Kabupaten Simalungun
    Ichwan Alamsyah Lubis, Ramadhan Bestari, Umar Zein, Pandu Prabowo Warsodirejo
    Wahana Jurnal Pengabdian kepada Masyarakat.2024; 2(2): 53.     CrossRef
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    Wenjie Mu, Pingping Ma, Yugui Wang, Yaqi Li, Yingying Ding, Yang Zou, Lixia Pu, Qi Yan, Haoyue Kong, Xiaola Guo, Aijiang Guo, Hailong Li, Shuai Wang
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    Simone Bariselli, Giulia Maioli, Giovanni Pupillo, Mattia Calzolari, Deborah Torri, Letizia Cirasella, Andrea Luppi, Camilla Torreggiani, Chiara Garbarino, Filippo Barsi, Gianluca Rugna, Michele Dottori
    International Journal for Parasitology: Parasites and Wildlife.2023; 22: 20.     CrossRef
  • Molecular Identification and Appraisal of the Genetic Variation of Taenia saginata in Central Regions of Vietnam
    Giang Tran Thi, Ilenia Azzena, Fabio Scarpa, Piero Cossu, Cong Danh Le, Phuong Anh Ton Nu, Thi Minh Chau Ngo, Daria Sanna, Marco Casu
    Life.2022; 12(1): 70.     CrossRef
  • On Hazardous Pills for Weight Loss and Cysticercosis
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  • Genomic palaeoparasitology traced the occurrence of Taenia asiatica in ancient Iran (Sassanid Empire, 2th cent. CE–6th cent. CE)
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    Scientific Reports.2022;[Epub]     CrossRef
  • Zoonotic Taenia infections with focus on cysticercosis due to Taenia solium in swine and humans
    Fela Mendlovic, Agnes Fleury, Ana Flisser
    Research in Veterinary Science.2021; 134: 69.     CrossRef
  • Transcriptome Analysis and Autophagy Investigation of LoVo Cells Stimulated with Exosomes Derived from T. asiatica Adult Worms
    Panhong Liang, Yanping Li, Li Mao, Tingli Liu, Shaohua Zhang, Muhammad Ehsan, Liqun Wang, Aimin Guo, Guoliang Chen, Xuenong Luo
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  • Teniases caused by Taenia asiatica, Taenia saginata, Taenia solium
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  • Ten Cases of Taenia saginata Infection Confirmed by Analysis of the Internal Transcribed Spacer 1 rDNA Region in the Republic of Korea
    Su-Min Song, Hae Soo Yun, Dorene VanBik, Hyun-Ha Chang, Sang-Ah Lee, Shin-Woo Kim, Namhee Ryoo, Dong Yeub Eun, Nan Young Lee, Youn-Kyoung Goo, Yeonchul Hong, Meesun Ock, Hee-Jae Cha, Dong-Il Chung
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    Denis W. Spelman, Ar Kar Aung
    The American Journal of Tropical Medicine and Hygiene.2016; 94(5): 947.     CrossRef
  • Epidemiology and genetic diversity of Taenia asiatica: a systematic review
    Anita Ale, Bjorn Victor, Nicolas Praet, Sarah Gabriël, Niko Speybroeck, Pierre Dorny, Brecht Devleesschauwer
    Parasites & Vectors.2014;[Epub]     CrossRef
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  • 15,817 View
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Genetic Diversity of Taenia asiatica from Thailand and Other Geographical Locations as Revealed by Cytochrome c Oxidase Subunit 1 Sequences
Malinee Thairungroj Anantaphruti, Urusa Thaenkham, Dorn Watthanakulpanich, Orawan Phuphisut, Wanna Maipanich, Tippayarat Yoonuan, Supaporn Nuamtanong, Somjit Pubampen, Surapol Sanguankiat
Korean J Parasitol 2013;51(1):55-59.
Published online February 18, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.1.55

Twelve 924 bp cytochrome c oxidase subunit 1 (cox1) mitochondrial DNA sequences from Taenia asiatica isolates from Thailand were aligned and compared with multiple sequence isolates from Thailand and 6 other countries from the GenBank database. The genetic divergence of T. asiatica was also compared with Taenia saginata database sequences from 6 different countries in Asia, including Thailand, and 3 countries from other continents. The results showed that there were minor genetic variations within T. asiatica species, while high intraspecies variation was found in T. saginata. There were only 2 haplotypes and 1 polymorphic site found in T. asiatica, but 8 haplotypes and 9 polymorphic sites in T. saginata. Haplotype diversity was very low, 0.067, in T. asiatica and high, 0.700, in T. saginata. The very low genetic diversity suggested that T. asiatica may be at a risk due to the loss of potential adaptive alleles, resulting in reduced viability and decreased responses to environmental changes, which may endanger the species.

Citations

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  • Taenia asiatica: Mitochondrial signatures based analysis of an emerging public health threat in India
    Aman D. Moudgil, Anil K. Nehra, Pallavi Moudgil
    New Microbes and New Infections.2025; 63: 101562.     CrossRef
  • Identification of species and genetic variation in Taenia isolates from human and swine of North India
    Satyendra K. Singh, Kashi N. Prasad, Aloukick K. Singh, Kamlesh K. Gupta, Ranjeet S. Chauhan, Amrita Singh, Avinash Singh, Ravi P. Rai, Binod K. Pati
    Parasitology Research.2016; 115(10): 3689.     CrossRef
  • Epidemiology and genetic diversity of Taenia asiatica: a systematic review
    Anita Ale, Bjorn Victor, Nicolas Praet, Sarah Gabriël, Niko Speybroeck, Pierre Dorny, Brecht Devleesschauwer
    Parasites & Vectors.2014;[Epub]     CrossRef
  • Current Status of Taeniasis in Thailand
    Malinee Thairungroj Anantaphruti
    The Korean Journal of Parasitology.2013; 51(1): 37.     CrossRef
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Original Articles

Entamoeba histolytica Induces Cell Death of HT29 Colonic Epithelial Cells via NOX1-Derived ROS
Kyeong Ah Kim, Ju Young Kim, Young Ah Lee, Arim Min, Young Yil Bahk, Myeong Heon Shin
Korean J Parasitol 2013;51(1):61-68.
Published online February 18, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.1.61

Entamoeba histolytica, which causes amoebic colitis and occasionally liver abscess in humans, is able to induce host cell death. However, signaling mechanisms of colon cell death induced by E. histolytica are not fully elucidated. In this study, we investigated the signaling role of NOX in cell death of HT29 colonic epithelial cells induced by E. histolytica. Incubation of HT29 cells with amoebic trophozoites resulted in DNA fragmentation that is a hallmark of apoptotic cell death. In addition, E. histolytica generate intracellular reactive oxygen species (ROS) in a contact-dependent manner. Inhibition of intracellular ROS level with treatment with DPI, an inhibitor of NADPH oxidases (NOXs), decreased Entamoeba-induced ROS generation and cell death in HT29 cells. However, pan-caspase inhibitor did not affect E. histolytica-induced HT29 cell death. In HT29 cells, catalytic subunit NOX1 and regulatory subunit Rac1 for NOX1 activation were highly expressed. We next investigated whether NADPH oxidase 1 (NOX1)-derived ROS is closely associated with HT29 cell death induced by E. histolytica. Suppression of Rac1 by siRNA significantly inhibited Entamoeba-induced cell death. Moreover, knockdown of NOX1 by siRNA, effectively inhibited E. histolytica-triggered DNA fragmentation in HT29 cells. These results suggest that NOX1-derived ROS is required for apoptotic cell death in HT29 colon epithelial cells induced by E. histolytica.

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  • Involvement of NOX2-derived ROS in human hepatoma HepG2 cell death induced by Entamoeba histolytica
    Young Ah Lee, Myeong Heon Shin
    Parasites, Hosts and Diseases.2023; 61(4): 388.     CrossRef
  • Signaling Role of NADPH Oxidases in ROS-Dependent Host Cell Death Induced by Pathogenic Entamoeba histolytica
    Young Ah Lee, Seobo Sim, Kyeong Ah Kim, Myeong Heon Shin
    The Korean Journal of Parasitology.2022; 60(3): 155.     CrossRef
  • The interaction betweenEntamoeba histolyticaand enterobacteria shed light on an ancient antibacterial response
    Nancy Guillén
    Cellular Microbiology.2019;[Epub]     CrossRef
  • NOX4 activation is involved in ROS‐dependent Jurkat T‐cell death induced by Entamoeba histolytica
    Young Ah Lee, Kyeong Ah Kim, Arim Min, Myeong Heon Shin
    Parasite Immunology.2019;[Epub]     CrossRef
  • O-deGlcNAcylation is required for Entamoeba histolytica-induced HepG2 cell death
    Young Ah Lee, Arim Min, Myeong Heon Shin
    Microbial Pathogenesis.2018; 123: 285.     CrossRef
  • GOLPH3 expression promotes the resistance of HT29 cells to 5‑fluorouracil by activating multiple signaling pathways
    Ming‑Zhen Wang, Cheng‑Zhi Qiu, Wai‑Shi Yu, Yan‑Ta Guo, Chun‑Xiao Wang, Zhi‑Xiong Chen
    Molecular Medicine Reports.2017;[Epub]     CrossRef
  • Infection Strategies of Intestinal Parasite Pathogens and Host Cell Responses
    Bruno M. Di Genova, Renata R. Tonelli
    Frontiers in Microbiology.2016;[Epub]     CrossRef
  • A whole-genome RNAi screen uncovers a novel role for human potassium channels in cell killing by the parasite Entamoeba histolytica
    Chelsea Marie, Hans P. Verkerke, Dan Theodorescu, William A. Petri
    Scientific Reports.2015;[Epub]     CrossRef
  • Degradation of the Transcription Factors NF-κB, STAT3, and STAT5 Is Involved in Entamoeba histolytica-Induced Cell Death in Caco-2 Colonic Epithelial Cells
    Kyeong Ah Kim, Arim Min, Young Ah Lee, Myeong Heon Shin
    The Korean Journal of Parasitology.2014; 52(5): 459.     CrossRef
  • Protective action of NADPH oxidase inhibitors and role of NADPH oxidase in pathogenesis of colon inflammation in mice
    Rima Ramonaite
    World Journal of Gastroenterology.2014; 20(35): 12533.     CrossRef
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    Alí Francisco Citalán-Madrid, Alexander García-Ponce, Hilda Vargas-Robles, Abigail Betanzos, Michael Schnoor
    Tissue Barriers.2013; 1(5): e26938.     CrossRef
  • The EhCPADH112 Complex of Entamoeba histolytica Interacts with Tight Junction Proteins Occludin and Claudin-1 to Produce Epithelial Damage
    Abigail Betanzos, Rosario Javier-Reyna, Guillermina García-Rivera, Cecilia Bañuelos, Lorenza González-Mariscal, Michael Schnoor, Esther Orozco, Johanna M. Brandner
    PLoS ONE.2013; 8(6): e65100.     CrossRef
  • 10,951 View
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The Route of Leishmania tropica Infection Determines Disease Outcome and Protection against Leishmania major in BALB/c Mice
Hamid Mahmoudzadeh-Niknam, Ghader Khalili, Firoozeh Abrishami, Ali Najafy, Vahid Khaze
Korean J Parasitol 2013;51(1):69-74.
Published online February 18, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.1.69

Leishmania tropica is one of the causative agents of leishmaniasis in humans. Routes of infection have been reported to be an important variable for some species of Leishmania parasites. The role of this variable is not clear for L. tropica infection. The aim of this study was to explore the effects of route of L. tropica infection on the disease outcome and immunologic parameters in BALB/c mice. Two routes were used; subcutaneous in the footpad and intradermal in the ear. Mice were challenged by Leishmani major, after establishment of the L. tropica infection, to evaluate the level of protective immunity. Immune responses were assayed at week 1 and week 4 after challenge. The subcutaneous route in the footpad in comparison to the intradermal route in the ear induced significantly more protective immunity against L. major challenge, including higher delayed-type hypersensitivity responses, more rapid lesion resolution, lower parasite loads, and lower levels of IL-10. Our data showed that the route of infection in BALB/c model of L. tropica infection is an important variable and should be considered in developing an appropriate experimental model for L. tropica infections.

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  • The Immune Memory Response of In Vitro-Polarised Th1, Th2, and Th17 Cells in the Face of Ovalbumin-Transgenic Leishmania major in a Mouse Model
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    Bernard Ong’ondo Osero, Zama Cele, Raphael Taiwo Aruleba, Rebeng A. Maine, Mumin Ozturk, Manfred B. Lutz, Frank Brombacher, Ramona Hurdayal
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    Shima Nahidi, Elham Gholami, Yasaman Taslimi, Sima Habibzadeh, Negar Seyed, Elaheh Davarpanah, Alireza Ghanadan, Sima Rafati, Tahereh Taheri
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    Mosayeb Rostamian, Fariborz Bahrami, Hamid M. Niknam, Humberto Lanz-Mendoza
    PLOS ONE.2018; 13(9): e0204491.     CrossRef
  • Route of Infection Affects Pathogenicity of Leishmania major in BALB/c Mice
    Ehsan Sarreshteh, Mosayeb Rostamian, Mahsa Tat Asadi, Firoozeh Abrishami, Ali Najafi, Maryam Abolghazi, Hamid Mahmoudzadeh Niknam
    Journal of Medical Microbiology and Infectious Diseases .2017; 5(1): 26.     CrossRef
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  • Coinjection with TLR2 Agonist Pam3CSK4 Reduces the Pathology of Leishmanization in Mice
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  • Site-Dependent Recruitment of Inflammatory Cells Determines the Effective Dose of Leishmania major
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An Epidemiological Study of Cutaneous Leishmaniasis in Al-Jabal Al-Gharbi, Libya
Manal Z. M. Abdellatif, Khamis El-Mabrouk, Ashraf A. Ewis
Korean J Parasitol 2013;51(1):75-84.
Published online February 18, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.1.75

Cutaneous leishmaniasis (CL) is an endemic parasitic infection in the Mediterranean region, including Libya and its Al-jabal Al-gharbi province. We aimed at studying the occupational relevance as well as other epidemiological aspects of CL. We investigated 140 CL cases who attended at Gharyan outpatient polyclinic during a period of 6 months in 2009. CL infection was clinically diagnosed and confirmed by demonstration of Leishmania parasites on smears from lesions. Our findings showed that males were more affected than females (P=0.04), and people above 10-years were more affected than younger ones (P=0.0001). A significant percent of CL cases belonged to Al-Kawasem subprovince (P=0.0001). Farm-related activities were the most frequent occupations among CL cases (P=0.04). In addition to farm workers, housewives and students are at risk groups since they are engaged at farm activities. Moreover, those who have occupations that require staying outdoors for a part of night, e.g., policemen, are also at risk. Compared to children, adult CL patients had multiple lesions (P=0.001) that were more prevalent in their upper and lower extremities than the face (P=0.0001). We conclude that CL is a major health problem in Al-jabal Al-gharbi province of Libya. The presence of rodents and sandflies makes it a suitable environment for Leishmania to spread in an endemic epidemiological pattern. Being engaged in farming activities or outdoor occupations increases the risk of infection. Various clinical patterns of CL suggest the presence of more than 1 species of Leishmania at Al-jabal Al-gharbi province. We propose that the 2 species responsible for CL in this area are L. major and L. tropica. Further investigations to identify the leishmanial species responsible for CL at Al-jabal Al-gharbi together with adoption of preventive and control programs are needed.

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  • Entomological studies of phlebotomine sand flies (Diptera: Psychodidae) in relation to cutaneous leishmaniasis transmission in Al Rabta, North West of Libya
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Kinetics of IL-23 and IL-12 Secretion in Response to Toxoplasma gondii Antigens from THP-1 Monocytic Cells
Juan-Hua Quan, Wei Zhou, Guang-Ho Cha, In-Wook Choi, Dae-Whan Shin, Young-Ha Lee
Korean J Parasitol 2013;51(1):85-92.
Published online February 18, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.1.85

IL-23 and IL-12 are structurally similar and critical for the generation of efficient cellular immune responses. Toxoplasma gondii induces a strong cell-mediated immune response. However, little is known about IL-23 secretion profiles in T. gondii-infected immune cells in connection with IL-12. We compared the patterns of IL-23 and IL-12 production by THP-1 human monocytic cells in response to stimulation with live or heat-killed T. gondii tachyzoites, or with equivalent quantities of either T. gondii excretory/secretory proteins (ESP) or soluble tachyzoite antigen (STAg). IL-23 and IL-12 were significantly increased from 6 hr after stimulation with T. gondii antigens, and their secretions were increased with parasite dose-dependent manner. IL-23 concentrations were significantly higher than those of IL-12 at the same multiplicity of infection. IL-23 secretion induced by live parasites was significantly higher than that by heat-killed parasites, ESP, or STAg, whereas IL-12 secretion by live parasite was similar to those of ESP or STAg. However, the lowest levels of both cytokines were at stimulation with heat-killed parasites. These data indicate that IL-23 secretion patterns by stimulation with various kinds of T. gondii antigens at THP-1 monocytic cells are similar to those of IL-12, even though the levels of IL-23 induction were significantly higher than those of IL-12. The detailed kinetics induced by each T. gondii antigen were different from each other.

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    Mingzhu Deng, Feifei Gao, Tianfeng Liu, Weiqiang Zhan, Juanhua Quan, Ziquan Zhao, Xuyang Wu, Zhuolan Zhong, Hong Zheng, Jiaqi Chu
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    Hassan Ahmed Hassan Ahmed Ismail, Byung-Hun Kang, Jae-Su Kim, Jae-Hyung Lee, In-Wook Choi, Guang-Ho Cha, Jae-Min Yuk, Young-Ha Lee
    The Korean Journal of Parasitology.2017; 55(6): 613.     CrossRef
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    Emily J. Govro, Melissa K. Stuart
    Experimental Parasitology.2016; 169: 77.     CrossRef
  • Far beyond Phagocytosis: Phagocyte-Derived Extracellular Traps Act Efficiently against Protozoan ParasitesIn VitroandIn Vivo
    Liliana M. R. Silva, Tamara Muñoz-Caro, Rafael A. Burgos, Maria A. Hidalgo, Anja Taubert, Carlos Hermosilla
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    D. Pérez, M.C. Muñoz, J.M. Molina, T. Muñoz-Caro, L.M.R. Silva, A. Taubert, C. Hermosilla, A. Ruiz
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    Seyed Hossein Abdollahi, Fateme Ayoobi, Hossein Khorramdelazad, Behzad Nasiri Ahmadabadi, Mohammadtaghi Rezayati, Mohammad Kazemi Arababadi, Mohammad Zare-Bidaki
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  • Intracellular Networks of the PI3K/AKT and MAPK Pathways for Regulating Toxoplasma gondii-Induced IL-23 and IL-12 Production in Human THP-1 Cells
    Juan-Hua Quan, Jia-Qi Chu, Jaeyul Kwon, In-Wook Choi, Hassan Ahmed Hassan Ahmed Ismail, Wei Zhou, Guang-Ho Cha, Yu Zhou, Jae-Min Yuk, Eun-Kyeong Jo, Young-Ha Lee, Salvatore V Pizzo
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Monoclonal Antibody-Based Dipstick Assay: A Reliable Field Applicable Technique for Diagnosis of Schistosoma mansoni Infection Using Human Serum and Urine Samples
Zeinab Demerdash, Salwa Mohamed, Mohamed Hendawy, Ibrahim Rabia, Mohy Attia, Zeinab Shaker, Tarek M Diab
Korean J Parasitol 2013;51(1):93-98.
Published online February 18, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.1.93

A field applicable diagnostic technique, the dipstick assay, was evaluated for its sensitivity and specificity in diagnosing human Schistosoma mansoni infection. A monoclonal antibody (mAb) against S. mansoni adult worm tegumental antigen (AWTA) was employed in dipstick and sandwich ELISA for detection of circulating schistosome antigen (CSA) in both serum and urine samples. Based on clinical and parasitological examinations, 60 S. mansoni-infected patients, 30 patients infected with parasites other than schistosomiasis, and 30 uninfected healthy individuals were selected. The sensitivity and specificity of dipstick assay in urine samples were 86.7% and 90.0%, respectively, compared to 90.0% sensitivity and 91.7% specificity of sandwich ELISA. In serum samples, the sensitivity and specificity were 88.3% and 91.7% for dipstick assay vs. 91.7% and 95.0% for sandwich ELISA, respectively. The diagnostic efficacy of dipstick assay in urine and serum samples was 88.3% and 90.0%, while it was 90.8% and 93.3% for sandwich ELISA, respectively. The diagnostic indices of dipstick assay and ELISA either in serum or in urine were statistically comparable (P>0.05). In conclusion, the dipstick assay offers an alternative simple, rapid, non-invasive technique in detecting CSA or complement to stool examinations especially in field studies.

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    Maria Cristina Carvalho Espírito-Santo, Mónica Viviana Alvarado-Mora, Pedro Luiz Silva Pinto, Maria Carmen Arroyo Sanchez, Emmanuel Dias-Neto, Vera Lúcia Pagliusi Castilho, Elenice Messias do Nascimento Gonçalves, Pedro Paulo Chieffi, Expedito José de Alb
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Trematodes Recovered in the Small Intestine of Stray Cats in the Republic of Korea
Jong-Yil Chai, Young Yil Bahk, Woon-Mok Sohn
Korean J Parasitol 2013;51(1):99-106.
Published online February 18, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.1.99

In 2005, we reported the infection status of 438 stray cats with various species of intestinal helminths, including nematodes (4 species), trematodes (23 species), and cestodes (5 species) in the Republic of Korea. However, morphologic details of each helminth species have not been provided. In the present study, we intended to describe morphologic details of 13 trematode species which were either new fauna of cats (10 species) or new fauna of not only cats but also all animal hosts (3 species). The worms were fixed in 10% neutral buffered formalin under a cover slip pressure, stained with Semichon's acetocarmine, and then observed using a light microscope equipped with a micrometer. The 13 subjected species included members of the Heterophyidae (Stellantchasmus falcatus, Stictodora fuscata, Stictodora lari, Centrocestus armatus, Procerovum varium, and Cryptocotyle concava), Echinostomatidae (Echinostoma hortense, Echinostoma revolutum, Echinochasmus japonicus, and Stephanoprora sp.), Diplostomidae (Neodiplostomum seoulense), Plagiorchiidae (Plagiorchis muris), and Dicrocoeliidae (Eurytrema pancreaticum). By the present study, Cryptocotyle sp. and Neodiplostomum sp. recored in our previous study were identified as C. concava and N. seoulense, respectively. Three species, P. varium, C. concava, and Stephanoprora sp., are new trematode fauna in Korea.

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Fishborne Trematode Metacercariae in Luang Prabang, Khammouane, and Saravane Province, Lao PDR
Han-Jong Rim, Woon-Mok Sohn, Tai-Soon Yong, Keeseon S. Eom, Jong-Yil Chai, Duk-Young Min, Soon-Hyung Lee, Eui-Hyug Hoang, Bounlay Phommasack, Sithat Insisiengmay
Korean J Parasitol 2013;51(1):107-114.
Published online February 18, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.1.107

Fishborne trematode (FBT) metacercariae were investigated in fish from 3 Provinces of Lao PDR. Total 242 freshwater fish of 40 species were collected in local markets of Luang Prabang (59 fish of 16 species), Khammouane (81 fish of 19 species), and Saravane (97 fish of 14 species), and each of them was examined by artificial digestion method. Four species of metacercariae (Opisthorchis viverrini, Haplorchis taichui, Haplorchis yokogawai, and Centrocestus formosanus) were detected. O. viverrini was detected in 35 fish (14.5%), and their density was 252 per infected fish (Luang Prabang, 88 metacercariae in 5 fish; Khammouane, 187 in 6 fish; Saravane, 303 in 24 fish). H. taichui was found in 102 fish (42.1%), and their density was 485 per infected fish (Luang Prabang, 260 metacercariae in 38 fish; Khammouane, 1,084 in 23 fish; Saravane, 359 in 41 fish). H. yokogawai was detected in 92 fish (38.0%), and their density was 222 per infected fish (Luang Prabang, 362 metacercariae in 17 fish; Khammouane, 126 in 20 fish; Saravane, 214 in 55 fish). Metacercariae of C. formosanus were found in 8 fish (3.3%), and their density was 3 per infected fish. In the present study, it has been confirmed that FBT metacercariae, in particular, H. taichui, H. yokogawai, and O. viverrini, are highly prevalent in fish from Luang Prabang, Khammouane, and Saravane Province, Lao PDR.

Citations

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Case Reports

A Case of Anisakidosis Caused by Pseudoterranova decipiens Larva
Hak Kyun Na, Min Seo, Jong-Yil Chai, Eun Kyoung Lee, Soung Min Jeon
Korean J Parasitol 2013;51(1):115-117.
Published online February 18, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.1.115

Pseudoterranova decipiens larva is a rare cause of anisakiasis. Indeed, prior to the present study, there had been only 12 reports of larval P. decipiens infection in the Republic of Korea. In June 2011, an anisakid larva, 32.1 mm in length and 0.88 mm in width, and finally identified as the third stage larva of P. decipiens owing to the presence of an intestinal cecum but lacking ventricular appendage, was discovered in a 61-year-old woman during the course of endoscopy executed as a part of routine physical examinations. The patient had eaten raw a rockfish 13 hr prior to the endoscopy, but showed no symptoms of anisakiasis. This paper is the 13th report of P. decipiens infection in Korea.

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    A. Nordholm, J.A.L. Kurtzhals, A.M. Karami, P.W. Kania, K. Buchmann
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A Case of Oral Myiasis Caused by Lucilia sericata (Diptera: Calliphoridae) in Korea
Mun Jang, Seung-Min Ryu, Sang-Chang Kwon, Jun-Ouk Ha, Young-Hoon Kim, Dong-Hyun Kim, Soon-Myung Jung, Soon-Il Lee, Woon-Mok Sohn, Hee-Jae Cha, Meesun Ock
Korean J Parasitol 2013;51(1):119-123.
Published online February 18, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.1.119

We report here a case of oral myiasis in the Republic of Korea. The patient was a 37-year-old man with a 30-year history of Becker's muscular dystrophy. He was intubated due to dyspnea 8 days prior to admission to an intensive care unit (ICU). A few hours after the ICU admission, 43 fly larvae were found during suction of the oral cavity. All maggots were identified as the third instars of Lucilia sericata (Diptera: Calliphoridae) by morphology. We discussed on the characteristics of myiasis acquired in Korea, including the infection risk and predisposing factors.

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First Feline Case of Otodectosis in the Republic of Korea and Successful Treatment with Imidacloprid/Moxidectin Topical Solution
Ah-Jin Ahn, Dae-Sung Oh, Kyu-Sung Ahn, Sung-Shik Shin
Korean J Parasitol 2013;51(1):125-128.
Published online February 18, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.1.125

In April 2010, pruritic symptoms were recognized in 3 privately-owned Siamese cats raised in Gwangju, Korea. Examination of ear canals revealed dark brown, ceruminous otic exudates that contain numerous live mites at various developmental stages. Based on morphological characteristics of adult mites in which caruncles were present on legs 1 and 2 in adult females and on legs 1, 2, 3, and 4 in adult males while the tarsus of leg 3 in both sexes was equipped with 2 long setae, the mite was identified as Otodectes cynotis. Ten ear mite-free domestic shorthaired cats were experimentally infected with O. cynotis to evaluate the efficacy of 10% imidacloprid/1% moxidectin spot-on. Live mites were recovered from 1 of 10 treated cats on day 9 post-treatment (PT) while no live mites were observed from the ear canals of treated cats on days 16 and 30 PT. The efficacy of 10% imidacloprid/1% moxidectin spot-on on O. cynotis in cats was, therefore, 90% on day 9 and 100% on days 16 and 30 PT. This is the first report of otodectosis in 3 cats naturally infested with O. cynotis in Gwang-ju, Korea. Both natural and experimental infestations were successfully treated with 10% imidacloprid/1% moxidectin spot-on.

Citations

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  • Transcriptome Analysis of Otodectes cynotis in Different Developmental Stages
    Ran He, Qian Zhang, Xiaobin Gu, Yue Xie, Jing Xu, Xuerong Peng, Guangyou Yang
    Frontiers in Microbiology.2022;[Epub]     CrossRef
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    Li Hu, Ya-e Zhao, Dong-ling Niu, Rui Yang, Ji-hui Zeng
    Acta Parasitologica.2019; 64(2): 251.     CrossRef
  • Evidence‐based veterinary dermatology: a review of published studies of treatments forOtodectes cynotis(ear mite) infestation in cats
    Ching Yang, Hui‐Pi Huang
    Veterinary Dermatology.2016; 27(4): 221.     CrossRef
  • 12,078 View
  • 231 Download
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Brief Communications
Development of a Disperse Dye Immunoassay Technique for Detection of Antibodies against Neospora caninum in Cattle
Fatemeh Selahi, Mehdi Namavari, Mohammad Hossein Hosseini, Maryam Mansourian, Yahya Tahamtan
Korean J Parasitol 2013;51(1):129-132.
Published online February 18, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.1.129

In this study a disperse dye immunoassay method was standardized and evaluated for detection of antibodies against Neospora caninum in cattle. Sera from 150 cattle with a recent history of abortion were collected and tested by commercial ELISA kit and a standardized in-house dye immunoassay system. The positivity rate for the sera used in this study was 34.6% for the disperse dye immunoassay (DDIA) compared to 32% obtained by ELISA kit. This study showed no significant difference between DDIA and ELISA. The results indicated that the DDIA provide an economic, simple, rapid and robust test for detection of N. caninum infection in cattle.

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    Francine Alves Sinnott, Leonardo Garcia Monte, Thaís Farias Collares, Roberta Maraninchi Silveira, Sibele Borsuk
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    Sonia Almería, Fernando López-Gatius
    Research in Veterinary Science.2015; 100: 169.     CrossRef
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Increased Cytokine and Nitric Oxide Levels in Serum of Dogs Experimentally Infected with Rangelia vitalii
Francine C. Paim, Aleksandro S. Da Silva, Carlos Breno V. Paim, Raqueli T. Fran?a, M?rcio M. Costa, Marta M. M. F. Duarte, Manuela B. Sangoi, Rafael N. Moresco, Silvia G. Monteiro, Sonia Terezinha A. Lopes
Korean J Parasitol 2013;51(1):133-137.
Published online February 18, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.1.133

This study aimed to measure the levels of interferon-gamma (IFN-γ), tumor necrosis factor-alpha (TNF-α), interleukin 1 (IL-1), interleukin 6 (IL-6), and nitrite/nitrate (NOx) in serum of dogs experimentally infected with Rangelia vitalii. Twelve female mongrel dogs were divided into 2 groups; group A (uninfected controls) composed by healthy dogs (n=5) and group B consisting of dogs inoculated with R. vitalii (n=7). Animals were monitored by blood smear examinations, which showed intraerythrocytic forms of the parasite on day 5 post-infection (PI). Blood samples were collected through the jugular vein on days 0, 10, and 20 PI to determine the serum levels of IFN-γ, TNF-α, IL-1, IL-6, and NOx. Cytokines were assessed by ELISA quantitative sandwich technique, and NOx was measured by the modified Griess method. Cytokine levels (IFN-γ, TNF-α, IL-1, and IL-6) were increased (P<0.01) in serum of infected animals. Serum levels of NOx were also increased on days 10 PI (P<0.01) and 20 PI (P<0.05) in infected animals. Therefore, the infection with R. vitalii causes an increase in proinflammatory cytokines and nitric oxide content. These alterations may be associated with host immune protection against the parasite.

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Environmental Factors Related to Enterobiasis in a Southeast Region of Korea
Dong-Hee Kim, Min Kyoung Cho, Mi Kyung Park, Shin Ae Kang, Bo Young Kim, Sang Kyun Park, Hak Sun Yu
Korean J Parasitol 2013;51(1):139-142.
Published online February 18, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.1.139

Pinworm infection can occur through contact with contaminated surfaces followed by ingestion or even through inhalation of infective eggs. We have limited information regarding environmental contamination by eggs of Enterobius vermicularis. In order to determine environmental risk factors associated with the rate of E. vermicularis infection, we investigated possible environmental risk factors using a questionnaire from 46 kindergartens in 3 different cities of the southeast area of Korea. In total, using the cellotape anal swab technique, 3,422 children were examined for E. vermicularis infection. We evaluated E. vermicularis egg of books, educational materials, toys, room door handles, dusts of window edges, desks, chairs, tables, and dusts of classrooms. The overall egg-positive rate for E. vermicularis was 6.0%, and the prevalence of enterobiasis in each kindergarten ranged between 0% and 16.9%. We found that 78.9% of egg positive kindergartens were managed by private foundations, which was significantly higher, compared with kindergartens managed by public foundations or the nation. Compared with public or national kindergartens, most private kindergartens were located in residential areas and the number of children in these areas was significantly higher. In conclusion, numbers of children in kindergartens was found to be an environmental risk factor associated with transmission of enterobiasis in Korea.

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