Echinostoma flukes armed with 37 collar spines on their head collar are called as 37-collar-spined Echinostoma spp. (group) or ‘Echinostoma revolutum group’. At least 56 nominal species have been described in this group. However, many of them were morphologically close to and difficult to distinguish from the other, thus synonymized with the others. However, some of the synonymies were disagreed by other researchers, and taxonomic debates have been continued. Fortunately, recent development of molecular techniques, in particular, sequencing of the mitochondrial (nad1 and cox1) and nuclear genes (ITS region; ITS1-5.8S-ITS2), has enabled us to obtain highly useful data on phylogenetic relationships of these 37-collar-spined Echinostoma spp. Thus, 16 different species are currently acknowledged to be valid worldwide, which include E. revolutum, E. bolschewense, E. caproni, E. cinetorchis, E. deserticum, E. lindoense, E. luisreyi, E. mekongi, E. miyagawai, E. nasincovae, E. novaezealandense, E. paraensei, E. paraulum, E. robustum, E. trivolvis, and Echinostoma sp. IG of Georgieva et al., 2013. The validity of the other 10 species is retained until further evaluation, including molecular analyses; E. acuticauda, E. barbosai, E. chloephagae, E. echinatum, E. jurini, E. nudicaudatum, E. parvocirrus, E. pinnicaudatum, E. ralli, and E. rodriguesi. In this review, the history of discovery and taxonomic debates on these 26 valid or validity-retained species are briefly reviewed.
Citations
Citations to this article as recorded by
Development of a duplex loop-mediated isothermal amplification together with lateral flow dipstick assay for the detection and discrimination of parasitic infections in chickens between cestodes belonging to genus Raillietina and trematodes in family Echi Wasin Panich, Thanawan Tejangkura, Thapana Chontananarth Research in Veterinary Science.2025; 185: 105539. CrossRef
The ribosomal transcription units of five echinostomes and their taxonomic implications for the suborder Echinostomata (Trematoda: Platyhelminthes) Thanh Hoa Le, Linh Thi Khanh Pham, Dong Van Quyen, Khue Thi Nguyen, Huong Thi Thanh Doan, Weerachai Saijuntha, David Blair Parasitology Research.2024;[Epub] CrossRef
Epizootology of echinostomatidosis of geese I. Mullayarova, O. Nikolaeva, A. Andreeva, O. Altynbekov, C. Galieva, E. Muratova, M. Razyapov, M. Shaimuhametov, T. Itao, V. Perskaya, W. Yanmin, D. Morkovkin E3S Web of Conferences.2024; 494: 04029. CrossRef
Development and utilization of a visual loop-mediated isothermal amplification coupled with a lateral flow dipstick (LAMP-LFD) assay for rapid detection of Echinostomatidae metacercaria in edible snail samples Wasin Panich, Phonkawin Jaruboonyakorn, Awika Raksaman, Thanawan Tejangkura, Thapana Chontananarth International Journal of Food Microbiology.2024; 418: 110732. CrossRef
First molecular insights into gastrointestinal helminths of domestic birds in the Caspian Sea Littoral of Iran with an emphasis on the One Health concern Aida Vafae Eslahi, Majid Pirestani, Armin Aligolzadeh, Oskar Nowak, Elham Hajialilo, Pourya Fathollahzadeh, Fahimeh Hajiaghaee, Milad Badri, Luís Manuel Madeira de Carvalho Veterinary Parasitology: Regional Studies and Reports.2024; 51: 101035. CrossRef
Global distribution of zoonotic digenetic trematodes: a scoping review Yue Hu, Rong-Jian Zhan, Shi-Lin Lu, Yi-Yang Zhang, Min-Yu Zhou, Hui Huang, Ding-Ding Wang, Tao Zhang, Zi-Xin Huang, Yun-Fei Zhou, Zhi-Yue Lv Infectious Diseases of Poverty.2024;[Epub] CrossRef
Molecular epidemiological analyses reveal extensive connectivity between Echinostoma revolutum (sensu stricto) populations across Eurasia and species richness of zoonotic echinostomatids in England Egie E. Enabulele, Scott P. Lawton, Anthony J. Walker, Ruth S. Kirk, Hudson Alves Pinto PLOS ONE.2023; 18(2): e0270672. CrossRef
A new cryptic species of Echinostoma (Trematoda: Echinostomatidae) closely related to Echinostoma paraensei found in Brazil Marisa C. Valadão, Philippe V. Alves, Danimar López-Hernández, Jordana C. A. Assis, Paulo R. S. Coelho, Stefan M. Geiger, Hudson A. Pinto Parasitology.2023; 150(4): 337. CrossRef
A new species ofEchinostoma(Trematoda: Echinostomatidae) from the ‘revolutum’ group found in Brazil: refuting the occurrence ofEchinostoma miyagawai(=E. robustum) in the Americas Marisa C. Valadão, Danimar López-Hernández, Philippe V. Alves, Hudson A. Pinto Parasitology.2022; 149(3): 325. CrossRef
High diversity of trematode metacercariae that parasitize freshwater gastropods in Bangkok, Thailand, and their infective situations, morphologies and phylogenetic relationships Pichit Wiroonpan, Thapana Chontananarth, Jong-Yil Chai, Watchariya Purivirojkul Parasitology.2022; 149(7): 913. CrossRef
Neglected food-borne trematodiases: echinostomiasis and gastrodiscoidiasis Rafael Toledo, María Álvarez-Izquierdo, J. Guillermo Esteban, Carla Muñoz-Antoli Parasitology.2022; 149(10): 1319. CrossRef
General overview of the current status of human foodborne trematodiasis Jong-Yil Chai, Bong-Kwang Jung Parasitology.2022; 149(10): 1262. CrossRef
Morphological and molecular characterization of larval trematodes infecting the assassin snail genusAnentomein Thailand N. Chomchoei, T. Backeljau, B. Segers, C. Wongsawad, P. Butboonchoo, N. Nantarat Journal of Helminthology.2022;[Epub] CrossRef
Echinostoma miyagawai Ishii, 1932 (Echinostomatidae) from Ducks in Aceh Province, Indonesia with Special Reference to Its Synonymy with Echinostoma robustum Yamaguti, 1935 Jong-Yil Chai, Bong-Kwang Jung, Taehee Chang, Hyejoo Shin, Jaeeun Cho, Jin-Youp Ryu, Hyun-Seung Kim, Kwanghoon Park, Mun-Hyoo Jeong, Eui-Hyug Hoang, Marzuki Bin Muhammad Abdullah The Korean Journal of Parasitology.2021; 59(1): 35. CrossRef
Echinostoma mekongi: Discovery of Its Metacercarial Stage in Snails, Filopaludina martensi cambodjensis, in Pursat Province, Cambodia Jong-Yil Chai, Woon-Mok Sohn, Jaeeun Cho, Bong-Kwang Jung, Taehee Chang, Keon Hoon Lee, Virak Khieu, Rekol Huy The Korean Journal of Parasitology.2021; 59(1): 47. CrossRef
On the Helminth Fauna of the Muskrat (Ondatra zibethicus (Linnaeus, 1766)) in the Barnim District of Brandenburg State/Germany Rolf K. Schuster, Peter Specht, Siegfried Rieger Animals.2021; 11(8): 2444. CrossRef
Echinostoma mekongi n. sp. (Digenea: Echinostomatidae) from Riparian People along the Mekong River in Cambodia Jaeeun Cho, Bong-Kwang Jung, Taehee Chang, Woon-Mok Sohn, Muth Sinuon, Jong-Yil Chai The Korean Journal of Parasitology.2020; 58(4): 431. CrossRef
Fish-borne heterophyid trematodes are known to have a zoonotic potential, since at least 30 species are able to infect humans worldwide, with a global infection of around 7 million people. In this paper, a ‘state-of-the-art’ review of the South American heterophyid species is provided, including classical and molecular taxonomy, parasite ecology, host-parasite interaction studies and a list of species and their hosts. There is still a lack of information on human infections in South America with undetected or unreported infections probably due to the information shortage and little attention by physicians to these small intestinal flukes. Molecular tools for specific diagnoses of South American heterophyid species are still to be defined. Additional new sequences of Pygidiopsis macrostomum, Ascocotyle pindoramensis and Ascocotyle longa from Brazil are also provided.
Citations
Citations to this article as recorded by
Evaluation of benzocaine and eugenol as anesthetics and antiparasitic agents in a freshwater fish model M. C. Vercellini, A. Carranza-Martin, M. M. Montes, M. A. Ayala Aquaculture International.2025;[Epub] CrossRef
Eugenol-parasite interactions in ten spotted live-bearer fish Cnesterodon decemmaculatus: Seasonal and host-related effects M.C. Vercellini, A.C. Carranza-Martín, L. Morote, F. Maschi, M.M. Montes, M.A. Ayala Veterinary Parasitology: Regional Studies and Reports.2025; 62: 101288. CrossRef
Fish Pathogens and Associated Zoonotic Risks in Aquaculture: A Global One Health Perspective Fredrick Juma Syanya, Sajna Beegum, Zachariy Oreko Winam, Fazeena Fariq, A. R. Nikhila Khanna, Megha Lovejan, Mujeeb Rahiman K. M., Harikrishnan Mahadevan Aquaculture, Fish and Fisheries.2025;[Epub] CrossRef
Prevalence and molecular identification of fish-borne trematodes in endemic communities in Caraga region, Mindanao, Philippines Vachel Gay V. Paller, Jasmine Renette D. Jimenez, Allen Jethro I. Alonte, Vicente Y. Belizario Jr., Billy P. Divina, Kezia W. Kozel, Martha E. Betson Food and Waterborne Parasitology.2025; 41: e00302. CrossRef
Ultra-structure, genetic characterization and Immunological approach of fish borne zoonotic trematodes (Family: Heterophyidae) of a redbelly tilapia Mai A. Salem, Olfat A. Mahdy, Reem M. Ramadan Research in Veterinary Science.2024; 166: 105097. CrossRef
Description of new species of Trematoda from bats of Southeastern Mexico and a new classification for Brachylecithum rileyi n. comb. (Dicrocoeliidae) Wilson I. Moguel-Chin, Jesús Alonso Panti-May, Brenda Atziri García-García, David I. Hernández-Mena Systematic Parasitology.2024;[Epub] CrossRef
Phylogenetic assessment of Apophallines (Digenea: Opisthorchiidae) with revision of
Apophallus donicus
Skrjabin & Lindtrop, 1919 complex and some taxonomic propositions
Sergey G. Sokolov, Alexander V. Khrustalev, Spencer J. Greenwood, Caitlyn N. Gray, William T. Robbins, Megan E. B. Jones, Ekaterina L. Voropaeva, Alexander P. Kalmykov, Gadzhibek S. Dzhamirzoev, Dmitry M. Atopkin Systematics and Biodiversity.2023;[Epub] CrossRef
Black spot diseases in seven commercial fish species from the English Channel and the North Sea: infestation levels, identification and population genetics of Cryptocotyle spp. Maureen Duflot, Pierre Cresson, Maéva Julien, Léa Chartier, Odile Bourgau, Marialetizia Palomba, Simonetta Mattiucci, Graziella Midelet, Mélanie Gay Parasite.2023; 30: 28. CrossRef
The first new species of European Ascocotyle Looss, 1899 (Digenea: Heterophyidae) described in more than half a century Andrea Gustinelli, Monica Caffara, Dino Scaravelli, Maria Letizia Fioravanti, Tomáš Scholz International Journal for Parasitology: Parasites and Wildlife.2022; 17: 327. CrossRef
Pholeter gastrophilus (Trematoda: Heterophyidae), a parasite of dolphins from Brazilian waters Mariana Bertholdi Ebert, Ana Luisa Schiffino Valente, Marta Jussara Cremer, Reinaldo José da Silva Biologia.2021; 76(11): 3411. CrossRef
Cryptocotyle lata (Trematoda: Heterophyidae) Adult from a Korean Raccoon Dog, Nyctereutes procyonoides koreensis Heon Woo Lee, Eui Ju Hong, Hyeon Cheol Kim, Si Yun Ryu, Bae Keun Park The Korean Journal of Parasitology.2021; 59(6): 645. CrossRef
A serological survey was performed using ELISA to estimate the prevalence of tissue and luminal helminthic infections among hospital patients in Hanoi region, Vietnam. An overall seroprevalence of tissue and luminal helminthiases was 64.0% (95% CI 61.2-66.8) among 1,120 patients who visited Hanoi Medical University Hospital, Vietnam in 2018. The highest seroprevalence was observed against Toxocara spp. (59.0%), followed by Strongyloides stercoralis (46.3%), Gnathostoma spp. (25.5%), cysticercus (12.8%), Angiostrongylus cantonensis (10.5%), Fasciola spp. (11.1%), and Clonorchis sinensis (8.7%). Mono-infection by one species (11.1%) was lower than multiple infections (53.0%) (P<0.05). The seroprevalence in males (59.3%) was lower than in females (66.2%) but not statistically significant (P>0.05). Children (<15 years) revealed lower seroprevalence (34.0%) than adults (68.4%), and the age group 51-70 years revealed the highest seroprevalence (76.0%). Among the seropositive patients, eosinophilia (≥8.0%) was noted in 80.2%. The present results suggested active transmission of various tissue and luminal helminths among people in Hanoi, Vietnam.
Citations
Citations to this article as recorded by
Seroprevalence and associated risk factors of human fascioliasis in Yen Bai and Thanh Hoa provinces, Vietnam Thao Thi Bich Nguyen, Hafid Dahma, Veronique Dermauw, Dung Thi Bui, Bertrand Losson, Pierre Dorny, Dung Trung Do, Olivier Vandenberg Parasitology International.2026; 112: 103219. CrossRef
Toxocara seroprevalence among suspected patients across different geographical regions in Vietnam: A retrospective study Trinh Thi Que, Tran Van Chieu, Trieu Thuy Anh, Pham Van Ngai, Pham Van Tran, Nguyen Thai Son, Do Ngoc Anh Journal of Microbiology, Immunology and Infection.2025;[Epub] CrossRef
The seroprevalence of toxocariasis and related risk factors in children in Ho Chi Minh City, Vietnam: results from a school-based cross-sectional study Thieu V Ha, Tien T N Vo, Duy K H Dang, Y M L Tran, Thanh V Kim, Duc H Le, Lan-Anh T Do, Hong K Tang Transactions of The Royal Society of Tropical Medicine and Hygiene.2024; 118(6): 384. CrossRef
Fasciola spp. in Southeast Asia: A systematic review Vinh Hoang Quang, Bruno Levecke, Dung Do Trung, Brecht Devleesschauwer, Binh Vu Thi Lam, Kathy Goossens, Katja Polman, Steven Callens, Pierre Dorny, Veronique Dermauw, Krystyna Cwiklinski PLOS Neglected Tropical Diseases.2024; 18(1): e0011904. CrossRef
Fascioliasis, una zoonosis emergente en Perú y el mundo: factores asociados a la infección en niños de edad escolar A. Valderrama–Pomé Revista de la Facultad de Medicina Veterinaria y de Zootecnia.2023;[Epub] CrossRef
Prevalence of Strongyloides in Southeast Asia: a systematic review and meta-analysis with implications for public health and sustainable control strategies Abigail Hui En Chan, Teera Kusolsuk, Dorn Watthanakulpanich, Wallop Pakdee, Pham Ngoc Doanh, Azlin Mohd Yasin, Paron Dekumyoy, Urusa Thaenkham Infectious Diseases of Poverty.2023;[Epub] CrossRef
Seroprevalence of toxocariasis among allergic patients in Kuwait and its association with eosinophilia Mohammad Al-Awadhi, Wafaa Jamal Parasite Epidemiology and Control.2022; 18: e00260. CrossRef
Human Fascioliasis: Current Epidemiological Status and Strategies for Diagnosis, Treatment, and Control
Maria Alejandra Caravedo, Miguel Cabada Research and Reports in Tropical Medicine.2020; Volume 11: 149. CrossRef
Toxoplasma gondii is an intracellular parasite that causes severe disease when the infection occurs during pregnancy. Adenosine is a purine nucleoside involved in numerous physiological processes; however, the role of adenosine receptors in T. gondii-induced trophoblast cell function has not been investigated until now. The goal of the present study was to evaluate the intracellular signaling pathways regulated by adenosine receptors using a HTR-8/SVneo trophoblast cell model of T. gondii infection. HTR8/SVneo human extravillous trophoblast cells were infected with or without T. gondii and then evaluated for cell morphology, intracellular proliferation of the parasite, adenosine receptor expression, TNF-α production and mitogen-activated protein (MAP) kinase signaling pathways triggered by adenosine A3 receptor (A3AR). HTR8/SVneo cells infected with T. gondii exhibited an altered cytoskeletal changes, an increased infection rate and reduced viability in an infection time-dependent manner. T. gondii significantly promoted increased TNF-α production, A3AR protein levels and p38, ERK1/2 and JNK phosphorylation compared to those observed in uninfected control cells. Moreover, the inhibition of A3AR by A3AR siRNA transfection apparently suppressed the T. gondii infection-mediated upregulation of TNF-α, A3AR production and MAPK activation. In addition, T. gondii-promoted TNF-α secretion was dramatically attenuated by pretreatment with PD098059 or SP600125. These results indicate that A3AR-mediated activation of ERK1/2 and JNK positively regulates TNF-α secretion in T. gondii-infected HTR8/SVneo cells.
Citations
Citations to this article as recorded by
LINC00152 knockdown exerts repressive effects on epithelial-mesenchymal transition in bladder cancer Guoping Wang, Meijun Han, Fei Chen, Jinquan Liu, Jie Zhang Cytotechnology.2025;[Epub] CrossRef
Structural Simplification from Tricyclic to Bicyclic Scaffolds: A Long-Term Investigation in the Field of Adenosine Receptor Antagonists Costanza Ceni, Sara Calenda, Giulia Vagnoni, Daniela Catarzi, Flavia Varano, Vittoria Colotta Cells.2025; 14(18): 1480. CrossRef
Suppression by central adenosine A3 receptors of the cholinergic defense against cardiovascular aberrations of sepsis: role of PI3K/MAPKs/NFκB signaling Amany E. El-Naggar, Mai M. Helmy, Sahar M. El-Gowilly, Mahmoud M. El-Mas Frontiers in Pharmacology.2024;[Epub] CrossRef
Modeling the human placental barrier to understand Toxoplasma gondii´s vertical transmission Paula Faral-Tello, Romina Pagotto, Mariela Bollati-Fogolín, Maria E. Francia Frontiers in Cellular and Infection Microbiology.2023;[Epub] CrossRef
TNF-α/anti-TNF-αdrugs and its effect on pregnancy outcomes Fang-fang Dai, Min Hu, Yu-wei Zhang, Rong-hui Zhu, Li-ping Chen, Zhi-dian Li, Yan-jie Huang, Wei Hu, Yan-xiang Cheng Expert Reviews in Molecular Medicine.2022;[Epub] CrossRef
Adult ascarid worms from the field mice, Apodemus agrarius, were observed with a light and scanning electron microscope, and molecularly analized with 18S rRNA gene. In the scanning electron microscope, 3 prominent labia were present in the anterior end of male and female worms, but the interlabia and gubernaculum were absent. Scanning electron micrographs showed cervical alae as vestigial organs that looked like a slightly uplifted superficial sewing stitch. Total 6 pairs of post-cloacal papillae were observed on the tail of the male worms. The tail of female worms was blunt and conical shape with a spine-like structure, mucron. The eggs were sub-globular, coated with the albuminous layer and 73 by 82 μm in average size. The superficial pits of T. apodemi egg (mean 8.6×6.7 μm) are obviously bigger than those of Toxocara spp. The partial sequence of 18S rRNA showed the sequence homology of Toxocara canis (99.6%), Toxocara cati (99.4%), Toxascaris leonina (99.4%), and Toxocara vitulorum (99.2%). Conclusively, it was confirmed that ascarid nematodes, Toxocara apodemi, recovered from striped field mice in Korea are taxonomically conspecific relationship with genus Toxocara and genetic divergence from other Toxocara species.
Citations
Citations to this article as recorded by
First molecular characterization and species validation of Toxocara alienata (Rudolphi 1819) (Nematoda: Ascarididae), from a crab-eating raccoon (Procyon cancrivorus) Gustavo Macêdo do Carmo, Lorena Gisela Ailán-Choke, Hassan Jerdy, Hermínio Ismael de Araújo-Júnior, Felipe Bisaggio Pereira Parasitology International.2026; 111: 103160. CrossRef
Parasites in the Digestive Tract of Lion (Panthera leo) at the Safari Park of Gurun Putih Lestari Jantho, Aceh Besar Fajri Dwitama, Razali Daud, Arman Sayuti, Yudha Fahrimal Journal of Applied Veterinary Science And Technology.2025; 6(1): 32. CrossRef
Nematocidal activity of zinc oxide nanoparticles synthesized using chicken egg albumin in lung and spleen of Parascaris equorum experimentally infected rats Sara Bayoumi Ali, Ayman Saber Mohamed, Sohair R. Fahmy, Manal El–Garhy, Mohamed R. Mousa, Fathy Abdel-Ghaffar Scientific Reports.2025;[Epub] CrossRef
Incidence and Risk Factors of Toxocara vitulorum Infection in Beef Cattle of Yogyakarta, Indonesia Vika Ichsania Ninditya, Fitrine Ekawasti, Joko Prastowo, Irkham Widiyono, Wisnu Nurcahyo World's Veterinary Journal.2024; 14(4): 592. CrossRef
Characterisation of the mitochondrial genome and phylogenetic analysis of Toxocara apodemi (Nematoda: Ascarididae) Y. Gao, Y. Hu, S. Xu, H. Liang, H. Lin, T. H. Yin, K. Zhao Journal of Helminthology.2024;[Epub] CrossRef
The Complete Mitogenome of Toxocara vitulorum: Novel In-Sights into the Phylogenetics in Toxocaridae Yue Xie, Lidan Wang, Yijun Chen, Zhao Wang, Pengchen Zhu, Zun Hu, Xinfeng Han, Zhisheng Wang, Xuan Zhou, Zhicai Zuo Animals.2022; 12(24): 3546. CrossRef
Hyun Beom Song, Deokho Lee, Yan Jin, Jinwoo Kang, Shin-Hyeong Cho, Min Sun Park, Jin-Ho Park, Woo-Jung Song, Hye-Ryun Kang, Sang Hyub Lee, Sung-Tae Hong, Min-Ho Choi
Korean J Parasitol 2020;58(4):413-419. Published online August 26, 2020
Eosinophilia occurs commonly in many diseases including allergic diseases and helminthic infections. Toxocariasis has been suggested as one cause of eosinophilia. The present study was undertaken to examine the prevalence of toxocariasis in patients with eosinophilia and to identify the risk factors for toxocariasis. This prospective cohort study recruited a total of 81 patients with eosinophilia (34 males and 47 females) who visited the outpatient clinic at Seoul National University Hospital from January 2017 to February 2018 and agreed to participate in this study. The prevalence of toxocariasis was examined by T. canis-specific ELISA, and the various risk factors for toxocariasis were evaluated by a questionnaire survey. Among 81 patients with eosinophilia, 18 were positive for anti-T. canis antibodies (22.2%); 88.9% were male (16/18) and 11.1% were female (2/18). Multivariate statistical analysis revealed that males (OR 21.876, 95% CI: 1.667-287.144) with a history of consuming the raw meat or livers of animals (OR 5.899, 95% CI: 1.004-34.669) and a heavy alcohol-drinking habit (OR 8.767, 95% CI: 1.018-75.497) were at higher risk of toxocariasis in patients with eosinophilia. Toxocariasis should be considered a potential cause of eosinophilia when the patient has a history of eating the raw meat or livers of animals in Korea. A single course of albendazole is recommended to reduce the migration of Toxocara larvae in serologically positive cases with eosinophilia.
Citations
Citations to this article as recorded by
Evaluation of a Multiplex Bead Assay for Strongyloides stercoralis diagnosis using the recombinant antigen rSs-NIE-1 Joelma Nascimento de Souza, Wéslei Almeida Costa Araújo, Márcia Cristina Aquino Teixeira, Neci Matos Soares Diagnostic Microbiology and Infectious Disease.2026; 114(2): 117108. CrossRef
High toxocariasis seroprevalence in a tri-border indigenous community (Brazil, Paraguay and Argentina): A One Health perspective Isabella Braghin Ferreira, Roberto Teixeira de Souza Filho, Susana Angélica Zevallos Lescano, Rogério Giuffrida, Daniele Rodrigues, Suelen Teixeira de Faria Resende, Fabiano Borges Figueiredo, Louise Bach Kmetiuk, Andrea Pires dos Santos, Alexander Welker One Health.2025; 21: 101106. CrossRef
Human toxocariasis Susana Lopez-Alamillo, Pravallika Padyala, Megan Carey, Megan M. Duffey, Jill E. Weatherhead, Louisa A. Messenger, Bachir Medrouh, Marcelo U. Ferreira Clinical Microbiology Reviews.2025;[Epub] CrossRef
First Report on the Seroprevalence and Risk Factors Associated with Toxocara Infection in Blood Donors from Romania Ana Alexandra Ardelean, Rodica Lighezan, Sorin Ursoniu, Sergiu Adrian Sprintar, Daniela Adriana Oatis, Alin Gabriel Mihu, Maria Alina Lupu, Tudor Rareș Olariu Pathogens.2025; 14(9): 857. CrossRef
TỶ LỆ VÀ YẾU TỐ LIÊN QUAN NHIỄM TOXOCARA CANIS TẠI PHÒNG KHÁM BỆNH VIỆN ĐẠI HỌC Y DƯỢC 1 THÀNH PHỐ HỒ CHÍ MINH Nguyễn Ngọc Phi Anh Nguyễn Ngọc Phi Anh, Trần Thị Kim Dung Trần Thị Kim Dung, Huỳnh Thị Thu Thảo Huỳnh Thị Thu Thảo Tạp Chí Khoa Học Trường Đại Học Quốc Tế Hồng Bàng.2024; : 213. CrossRef
Toxocariasis: potential association with bronchial asthma, and pneumonia among pediatric children Wegdan M. Abd El Wahab, Mona I. Ali, Shimaa S. Ibrahim, Yasmen A. Mohamed, Doaa A. Hamdy Journal of Parasitic Diseases.2023; 47(1): 93. CrossRef
One health approach to toxocariasis in quilombola communities of southern Brazil Vamilton Alvares Santarém, Giovanni Kalempa Panazzolo, Louise Bach Kmetiuk, Orlei José Domingues, Isabella Braghin Ferreira, Roberto Teixeira de Souza Filho, João Henrique Farinhas, Fernando Rodrigo Doline, Susana Angélica Zevallos Lescano, Leandro Menegu Parasites & Vectors.2023;[Epub] CrossRef
Seroprevalence of toxocariasis among allergic patients in Kuwait and its association with eosinophilia Mohammad Al-Awadhi, Wafaa Jamal Parasite Epidemiology and Control.2022; 18: e00260. CrossRef
Green vegetable juice as a potential source of human fascioliasis in Korea Sungim Choi, Sunghee Park, Sooji Hong, Hyejoo Shin, Bong-Kwang Jung, Min Jae Kim One Health.2022; 15: 100441. CrossRef
Serosurvey of anti-Toxocara canis antibodies in people experiencing homelessness and shelter workers from São Paulo, Brazil Vamilton Alvares Santarém, Anahi Chechia do Couto, Susana Zevallos Lescano, William Henry Roldán, Ruana Renostro Delai, Rogério Giuffrida, Louise Bach Kmetiuk, Alexander Welker Biondo, Sriveny Dangoudoubiyam, Andrea Pires dos Santos Parasites & Vectors.2022;[Epub] CrossRef
Seroprevalence of Toxocariasis Among Hypereosinophilic Children: A Single Center Study, Tehran, Iran Meysam Sharifdini, Mehdi Zarean, Mehrzad Sadredinamin, Mitra Zare- Bavani, Sarah Sharifi-yazdi, Bahram Nikmanesh Archives of Pediatric Infectious Diseases.2022;[Epub] CrossRef
The Role of Nile Tilapia (Oreochromis niloticus) in the Life Cycle of Toxocara spp. Everton André de Oliveira, Yslla Fernanda Fitz Balo Merigueti, Isabella Braghin Ferreira, Isabele Santos Garcia, Alini Soriano Pereira, Rosemeire de Souza Santos, Louise Bach Kmetiuk, Andrea Pires dos Santos, Alexander Welker Biondo, Rogerio Giuffrida, Va Frontiers in Veterinary Science.2021;[Epub] CrossRef
Seungman Cha, Sung-Tae Hong, Jin-Su Lee, Hoo Gn Jeong, In-Sun Kwon, Abd Al Wahab Saed, Mousab Siddig Elhag, Hassan Ahmed Hassan Ahmed Ismail, Mutamad Amin, Young-Ha Lee
Korean J Parasitol 2020;58(4):421-430. Published online August 25, 2020
This study aimed to investigate whether mass drug administration (MDA) intervention has an equivalent effect on reducing the prevalence and intensity of Schistosoma haematobium infection regardless of the baseline values. A repeated cross-sectional survey was performed targeting students of 12 primary schools in Al Jabalain and El Salam districts of White Nile State, Sudan, at both 1 week before and 8 months after the MDA. Prior to the baseline survey, school-aged children in Al Jabalain had received MDA interventions twice in 4 years, while those in El Salam had not. The baseline prevalence was 9.1% in Al Jabalain and 35.2% in El Salam, which were reduced to 1.8% and 5.5% at 8 months after the MDA, respectively. The corresponding reduction rates were 80.3% and 84.4%, not significant difference between both districts. However, changes in the geometric mean intensity (GMI) of egg counts were significantly different between both districts. The baseline GMIs were 14.5 eggs per 10 ml of urine (EP10) in Al Jabalain and 18.5 EP10 in El Salam, which were reduced to 7.1 and 11.2 EP10 after treatment, respectively. The corresponding reduction rates were 51.0% and 39.5%. In conclusion, MDA interventions were found to bring about similar relative reduction in prevalence regardless of the baseline value; however, the relative reduction in infection intensity was more salient in the district with a low baseline value for both prevalence and intensity. This clearly points to the importance of repeated MDA interventions in endemic areas, which will eventually contribute to schistosomiasis elimination.
Citations
Citations to this article as recorded by
Prevalence and Risk Factors of Schistosomiasis in Sudan: A Systematic Review and Meta-Analysis Yousef Alsaafin, Ayman Omer, Osama Felemban, Sarra Modawi, Maydolin Ibrahim, Abdullah Mohammed, Ammar Elfaki, Ahmed Abushara, Maryam A SalahEldin Cureus.2024;[Epub] CrossRef
Programmatic Implications for Schistosomiasis Elimination Based on Community-Based Survey in the Blue Nile, North Kordofan, and Sennar States, Sudan Hassan Ahmed Hassan Ahmed Ismail, Seungman Cha, Yan Jin, Sung-Tae Hong Life.2023; 13(4): 1049. CrossRef
Implications for selecting persistent hot spots of schistosomiasis from community- and school-based surveys in Blue Nile, North Kordofan, and Sennar States, Sudan Hassan Ahmed Hassan Ahmed Ismail, Seungman Cha, Yan Jin, Sung-Tae Hong Parasites, Hosts and Diseases.2023; 61(2): 216. CrossRef
Review of Recent Prevalence of Urogenital Schistosomiasis in Sub-Saharan Africa and Diagnostic Challenges in the Field Setting Sung-Tae Hong Life.2023; 13(8): 1670. CrossRef
Investigation of Intestinal and Blood Parasites in People Returning to Turkey with a History of Traveling Abroad During the Pandemic Abdurrahman Ekici, Esra Gürbüz, Ahmet Hakan Ünlü, Rahmi Yıldız, Selahattin Aydemir, Ahmed Galip Halidi, Nuriz Ödemiş, Sinan Karakuş, Şehriban Yürektürk, Mutalip Çiçek, Hasan Yılmaz Turkish Journal of Parasitology.2022; 46(2): 108. CrossRef
Transmission Dynamics of Schistosoma haematobium among School-Aged Children: A Cohort Study on Prevalence, Reinfection and Incidence after Mass Drug Administration in the White Nile State of Sudan Yan Jin, Young-Ha Lee, Seungman Cha, In-Uk Choi, Hassan Ahmed Hassan Ahmed Ismail, Mousab Siddig Elhag, Sung-Tae Hong International Journal of Environmental Research and Public Health.2021; 18(21): 11537. CrossRef
Urinary schistosomiasis and the associated bladder cancer: update Mohamed S. Zaghloul, Tarek M. Zaghloul, Mai K. Bishr, Brian C. Baumann Journal of the Egyptian National Cancer Institute.2020;[Epub] CrossRef
Echinostoma mekongi n. sp. (Digenea: Echinostomatidae) is described based on adult flukes collected from humans residing along the Mekong River in Cambodia. Total 256 flukes were collected from the diarrheic stool of 6 echinostome egg positive villagers in Kratie and Takeo Province after praziquantel treatment and purging. Adults of the new species were 9.0-13.1 (av. 11.3) mm in length and 1.3-2.5 (1.9) mm in maximum width and characterized by having a head collar armed with 37 collar spines (dorsal spines arranged in 2 alternative rows), including 5 end group spines. The eggs in feces and worm uterus were 98-132 (117) μm long and 62-90 (75) μm wide. These morphological features closely resembled those of Echinostoma revolutum, E. miyagawai, and several other 37-collar-spined Echinostoma species. However, sequencing of the nuclear ITS (ITS1-5.8S rRNA-ITS2) and 2 mitochondrial genes, cox1 and nad1, revealed unique features distinct from E. revolutum and also from other 37-collar-spined Echinostoma group available in GenBank (E. bolschewense, E. caproni, E. cinetorchis, E. deserticum, E. miyagawai, E. nasincovae, E. novaezealandense, E. paraensei, E. paraulum, E. robustum, E. trivolvis, and Echinostoma sp. IG). Thus, we assigned our flukes as a new species, E. mekongi. The new species revealed marked variation in the morphology of testes (globular or lobulated), and smaller head collar, collar spines, oral and ventral suckers, and cirrus sac compared to E. revolutum and E. miyagawai. Epidemiological studies regarding the geographical distribution and its life history, including the source of human infections, remain to be performed.
Citations
Citations to this article as recorded by
The Nuclear Ribosomal Transcription Units of Two Echinostomes and Their Taxonomic Implications for the Family Echinostomatidae Yu Cao, Ye Li, Zhong-Yan Gao, Bo-Tao Jiang Biology.2025; 14(8): 1101. CrossRef
Prevalence of Foodborne Trematodes in Small Indigenous Fish Species in Local Markets of Phnom Penh, Cambodia Domenico Caruso, Lin Kong, Samnang Keo, Sreyni Yoeurn, Samphal Seng Vector-Borne and Zoonotic Diseases.2024; 24(3): 141. CrossRef
High Prevalence of Echinostoma mekongi Infection in Schoolchildren and Adults, Kandal Province, Cambodia Bong-Kwang Jung, Taehee Chang, Seungwan Ryoo, Sooji Hong, Jeonggyu Lee, Sung-Jong Hong, Woon-Mok Sohn, Virak Khieu, Rekol Huy, Jong-Yil Chai Emerging Infectious Diseases.2024;[Epub] CrossRef
Development and utilization of a visual loop-mediated isothermal amplification coupled with a lateral flow dipstick (LAMP-LFD) assay for rapid detection of Echinostomatidae metacercaria in edible snail samples Wasin Panich, Phonkawin Jaruboonyakorn, Awika Raksaman, Thanawan Tejangkura, Thapana Chontananarth International Journal of Food Microbiology.2024; 418: 110732. CrossRef
First molecular insights into gastrointestinal helminths of domestic birds in the Caspian Sea Littoral of Iran with an emphasis on the One Health concern Aida Vafae Eslahi, Majid Pirestani, Armin Aligolzadeh, Oskar Nowak, Elham Hajialilo, Pourya Fathollahzadeh, Fahimeh Hajiaghaee, Milad Badri, Luís Manuel Madeira de Carvalho Veterinary Parasitology: Regional Studies and Reports.2024; 51: 101035. CrossRef
Characterization of Echinostoma spp. (Trematoda: Echinostomatidae Looss, 1899) infecting ducks in south-eastern Australia Madeleine Ray, Michael Trinidad, Nidhish Francis, Shokoofeh Shamsi International Journal of Food Microbiology.2024; 421: 110754. CrossRef
Genetic diversity and population structure of the helminths intermediate host Anentome helena (von dem Busch, 1847) in northern Thailand Nithinan Chomchoei, Chalobol Wongsawad, Preeyaporn Butboonchoo, Nattawadee Nantarat Asian Pacific Journal of Tropical Medicine.2024; 17(12): 536. CrossRef
High endemicity of Opisthorchis viverrini infection among people in northern Cambodia confirmed by adult worm expulsion Bong-Kwang Jung, Sooji Hong, Taehee Chang, Jaeeun Cho, Seungwan Ryoo, Keon Hoon Lee, Jeonggyu Lee, Woon-Mok Sohn, Sung-Jong Hong, Virak Khieu, Rekol Huy, Jong-Yil Chai Scientific Reports.2023;[Epub] CrossRef
High diversity of trematode metacercariae that parasitize freshwater gastropods in Bangkok, Thailand, and their infective situations, morphologies and phylogenetic relationships Pichit Wiroonpan, Thapana Chontananarth, Jong-Yil Chai, Watchariya Purivirojkul Parasitology.2022; 149(7): 913. CrossRef
Neglected food-borne trematodiases: echinostomiasis and gastrodiscoidiasis Rafael Toledo, María Álvarez-Izquierdo, J. Guillermo Esteban, Carla Muñoz-Antoli Parasitology.2022; 149(10): 1319. CrossRef
General overview of the current status of human foodborne trematodiasis Jong-Yil Chai, Bong-Kwang Jung Parasitology.2022; 149(10): 1262. CrossRef
Echinostoma mekongi: Discovery of Its Metacercarial Stage in Snails, Filopaludina martensi cambodjensis, in Pursat Province, Cambodia Jong-Yil Chai, Woon-Mok Sohn, Jaeeun Cho, Bong-Kwang Jung, Taehee Chang, Keon Hoon Lee, Virak Khieu, Rekol Huy The Korean Journal of Parasitology.2021; 59(1): 47. CrossRef
Echinostoma miyagawai Ishii, 1932 (Echinostomatidae) from Ducks in Aceh Province, Indonesia with Special Reference to Its Synonymy with Echinostoma robustum Yamaguti, 1935 Jong-Yil Chai, Bong-Kwang Jung, Taehee Chang, Hyejoo Shin, Jaeeun Cho, Jin-Youp Ryu, Hyun-Seung Kim, Kwanghoon Park, Mun-Hyoo Jeong, Eui-Hyug Hoang, Marzuki Bin Muhammad Abdullah The Korean Journal of Parasitology.2021; 59(1): 35. CrossRef
Acanthoparyphium shinanense n. sp. (Digenea: Echinostomatidae) from Experimental Chicks Infected with Metacercariae Encysted in Brackish Water Clams in the Republic of Korea Seungwan Ryoo, Bong-Kwang Jung, Taehee Chang, Sooji Hong, Hyejoo Shin, Jong-Yil Chai The Korean Journal of Parasitology.2021; 59(4): 341. CrossRef
Taxonomy of Echinostoma revolutum and 37-Collar-Spined Echinostoma spp.: A Historical Review Jong-Yil Chai, Jaeeun Cho, Taehee Chang, Bong-Kwang Jung, Woon-Mok Sohn The Korean Journal of Parasitology.2020; 58(4): 343. CrossRef
Trombiculid “chigger” mites (Acari) are ectoparasites that feed blood on rodents and another animals. A crosssectional survey was conducted in 7 ecosystems of southern Vietnam from 2015 to 2016. Chigger mites were identified with morphological characteristics and assayed by polymerase chain reaction for detection of rickettsiaceae. Overall chigger infestation among rodents was 23.38%. The chigger index among infested rodents was 19.37 and a mean abundance of 4.61. A total of 2,770 chigger mites were identified belonging to 6 species, 3 genera, and 1 family, and pooled into 141 pools (10-20 chiggers per pool). Two pools (1.4%) of the chiggers were positive for Orientia tsutsugamushi. Ricketsia spp. was not detected in any pools of chiggers. Further studies are needed including a larger number and diverse hosts, and environmental factors to assess scrub typhus.
Citations
Citations to this article as recorded by
A review on trombiculiasis: An underreported parasitosis that affects humans and animals, including world distribution, clinical findings, associated pathogens, prophylaxis and identification methods Isabella Pereira Pesenato, Ricardo Bassini-Silva, Fernando de Castro Jacinavicius Acta Tropica.2024; 260: 107420. CrossRef
Detection of Orientia tsutsugamushi in Novel Trombiculid Mite Species in Northern Tamil Nadu, India: Use of Targeting the Multicopy traD Gene John Antony Jude Prakash, Kannan Kamarasu, P Philip Samuel, Renu Govindarajan, Punitha Govindasamy, Liji Anna Johnson, P Ramalingam, J Nirmalson, K C Seran, Kevin Macaluso Journal of Medical Entomology.2022; 59(2): 693. CrossRef
Mapping the distributions of blood-sucking mites and mite-borne agents in China: a modeling study Tao Wang, Fanfei Meng, Tianle Che, Jinjin Chen, Haiyang Zhang, Yang Ji, Zhengwei Fan, Guoping Zhao, Wenhui Zhang, Baogui Jiang, Qiang Xu, Chenlong Lv, Taoxing Shi, Shiman Ruan, Lanzheng Liu, Wei Liu, Yang Yang, Liqun Fang Infectious Diseases of Poverty.2022;[Epub] CrossRef
Not Only Leptotrombidium spp. an Annotated Checklist of Chigger Mites (Actinotrichida: Trombiculidae) Associated with Bacterial Pathogens Hanna Moniuszko, Konrad Wojnarowski, Paulina Cholewińska Pathogens.2022; 11(10): 1084. CrossRef
International Rickettsia Disease Surveillance: An Example of Cooperative Research to Increase Laboratory Capability and Capacity for Risk Assessment of Rickettsial Outbreaks Worldwide Ju Jiang, Christina M. Farris, Kenneth B. Yeh, Allen L. Richards Frontiers in Medicine.2021;[Epub] CrossRef
A dataset of distribution and diversity of blood-sucking mites in China Fan-Fei Meng, Qiang Xu, Jin-Jin Chen, Yang Ji, Wen-Hui Zhang, Zheng-Wei Fan, Guo-Ping Zhao, Bao-Gui Jiang, Tao-Xing Shi, Li-Qun Fang, Wei Liu Scientific Data.2021;[Epub] CrossRef
This is a report of 2 cases of human hydatidosis caused by Echinococcus ortleppi in Vietnam. The patients were a 12-year-old male (case 1) having a cyst of 10.0×9.0 cm size in the lung and a 50-year-old female with a 3.0×3.3 cm-sized cyst in the heart. Eosinophilia was 33.7% in the male and 45.8% in the female patient. C-reactive protein was increased to 16.5 mg/L in the male and 18.2 mg/L in the female. Both patients were positive for ELISA at OD=2.5 and 3.1, respectively. Echinococcus protoscolices were collected from the cysts by amniocentesis and surgery. The protoscolices were identified as E. ortleppi by morphology and analysis of mitochondrial NADH dehydrogenase 1 (nad1) gene sequence. Both patients were cured by surgical resection of the hydatid cyst combined with albendazole medication. The E. ortleppi infection in lung is the second report, and the other in the heart is the first in Vietnam.
Citations
Citations to this article as recorded by
Current Perspectives on Cystic Echinococcosis: A Systematic Review Hawkar A. Nasralla, Berun A. Abdalla, Hiwa O. Abdullah, Sasan M. Ahmed, Fahmi H. Kakamad, Shvan H. Mohammed, Rawezh Q. Salih, Dahat A. Hussein, Tomas M. Mikael, Marwan N. Hassan, Hunar A. Hassan, Suhaib H. Kakamad, Kayhan A. Najar, Karukh K. Judi Clinical Journal.2025; 1(1): 12. CrossRef
Epidemiological study on bovine cystic echinococcosis: Abattoir survey, cyst characterization and its economic impact at Mekaneyesuse municipality abattoir, Northwest Ethiopia Belete Sendekie, Beyenech Gebeyehu, Abebe Mihret, Tesfu Kassa, Nigatu Kebede Parasite Epidemiology and Control.2024; 25: e00355. CrossRef
Echinococcus ortleppi infection in humans: An emerging zoonosis in Asia Ayako Yoshida, Takao Irie, Lan-Anh Le, Khanh-Linh Bui, Yukifumi Nawa Parasitology International.2024; 103: 102949. CrossRef
An overview of human helminthioses in Vietnam: Their prevention, control and lessons learnt Hung Manh Nguyen, Dung Trung Do, Stephen E. Greiman, Ha Van Nguyen, Hien Van Hoang, Toan Quoc Phan, Phuc Pham-Duc, Henry Madsen Acta Tropica.2023; 238: 106753. CrossRef
First report of Echinococcus ortleppi and genotype G6 of E. canadensis cluster from southern Punjab, Pakistan and a global overview on genetic structure and host adaptation of E. ortleppi Hira Muqaddas, Naunain Mehmood, Urmas Saarma, Ammarah Usman, Fahad Ahmed, Antonio Varcasia, Maria Francesca Sini, Muhammad Irfan Ullah Acta Tropica.2023; 244: 106951. CrossRef
Vietnam: Neglected tropical diseases in an emerging and accelerating economy Kala Pham, Peter J Hotez, Aaron R. Jex PLOS Neglected Tropical Diseases.2022; 16(2): e0010140. CrossRef
Species and genotypes belonging to Echinococcus granulosus sensu lato complex causing human cystic echinococcosis in Europe (2000–2021): a systematic review Adriano Casulli, Alessandro Massolo, Urmas Saarma, Gérald Umhang, Federica Santolamazza, Azzurra Santoro Parasites & Vectors.2022;[Epub] CrossRef
Cardiac hydatid cysts in a young man: A case report and a literature review Mircea Bajdechi, Dalia Manolache, Adrian Tudor, Mihnea Orghidan, Adriana Gurghean Experimental and Therapeutic Medicine.2022;[Epub] CrossRef
Genetic Characterization of Echinococcus granulosus Sensu Lato in Livestock and Human Isolates from North of Iran Indicates the Presence of E. ortleppi in Cattle Khadijeh Nematdoost, Keyhan Ashrafi, Bijan Majidi-Shad, Eshrat Beigom Kia, Arash Zeinali, Meysam Sharifdini Acta Parasitologica.2021; 66(2): 446. CrossRef
First Report of Echinococcus ortleppi in Free-Living Wild Boar (Sus scrofa) from Portugal Teresa Letra Mateus, Maria João Gargaté, Anabela Vilares, Idalina Ferreira, Manuela Rodrigues, Catarina Coelho, Madalena Vieira-Pinto Microorganisms.2021; 9(6): 1256. CrossRef
Extracellular vesicles of Echinococcus granulosus have therapeutic effects in allergic airway inflammation Mi Jin Jeong, Shin Ae Kang, Jun Ho Choi, Da In Lee, Hak Sun Yu Parasite Immunology.2021;[Epub] CrossRef
Terminologie à utiliser pour l’étude et la prise en charge des échinococcoses : adaptation du consensus international à la langue française A.P. Bellanger, K. Achour, S. Barkati, C. Bastid, S. Bresson-Hadni, B. Delaere, C. Dziri, B. Gottstein, M. Kachani, G. Mantion, G. Umhang, M. Wallon, D.A. Vuitton Bulletin de l'Académie Nationale de Médecine.2021; 205(8): 1028. CrossRef
The Pacific tapeworm Adenocephalus pacifcus (syn. Diphyllobothrium pacificum) is a causative agent of diphyllobothriosis occurred in Pacific coast of South America, mainly in Peru. Source of infections are traditional meal from raw or undercooked marine fish such as “cebiche”. We confirmed 3 new cases, one including scolex and the other two headless. A strobila 46 cm long without scolex was discharged from an 8-year-old boy before treatment. Specimens were confirmed morphologically by presence of tegumental protuberances on proglottids and small sized eggs. Partial sequence of cytochrome c oxidase subunit 1 gene was congruent with A. pacificus sequences.
Citations
Citations to this article as recorded by
Molecular identification and prevalence of plerocercoid larvae (Cestoda: Diphyllobothriidae) in some commercial fish species from Peru Aarón Mondragón-Martínez, Diego Marroquin-Vilchez, Rosa Martínez-Rojas, Lidia Cruz-Neyra, Eduardo A. Pulido-Murillo, Marcos A. Sulca-López, Celso Luis Cruces, Jhon Darly Chero, Enrique García-Candela, Jefferson Yunis-Aguinaga Parasitology Research.2024;[Epub] CrossRef
Presentación inusual de Diphyllobothrium pacificum: un caso de ileítis simulando linfoma Siomara Aransuzú Chávez-Sánchez, David Rafael Guevara-Lazo, Álvaro Bellido-Caparó, José Luis Pinto-Valdivia Revista de Gastroenterología del Perú.2024; 44(3): 288. CrossRef
Re‐evaluation of certain aspects of the EFSA Scientific Opinion of April 2010 on risk assessment of parasites in fishery products, based on new scientific data. Part 2 Ana Allende, Avelino Alvarez‐Ordóñez, Valeria Bortolaia, Sara Bover‐Cid, Alessandra De Cesare, Wietske Dohmen, Laurent Guillier, Lieve Herman, Liesbeth Jacxsens, Maarten Nauta, Lapo Mughini‐Gras, Jakob Ottoson, Luisa Peixe, Fernando Perez‐Rodriguez, Panag EFSA Journal.2024;[Epub] CrossRef
Toxoplasma gondii is an obligate intracellular protozoan parasite that can invade various organs in the host body, including the central nervous system. Chronic intracranial T. gondii is known to be associated with neuroprotection against neurodegenerative diseases through interaction with host brain cells in various ways. The present study investigated the neuroprotective effects of chronic T. gondii infection in mice with cerebral ischemia experimentally produced by middle cerebral artery occlusion (MCAO) surgery. The neurobehavioral effects of cerebral ischemia were assessed by measurement of Garcia score and Rotarod behavior tests. The volume of brain ischemia was measured by triphenyltetrazolium chloride staining. The expression levels of related genes and proteins were determined. After cerebral ischemia, corrected infarction volume was significantly reduced in T. gondii infected mice, and their neurobehavioral function was significantly better than that of the uninfection control group. Chronic T. gondii infection induced the expression of hypoxia-inducible factor 1-alpha (HIF-1α) in the brain before MCAO. T. gondii infection also increased the expression of vascular endothelial growth factor after the cerebral ischemia. It is suggested that chronic intracerebral infection of T. gondii may be a potential preconditioning strategy to reduce neural deficits associated with cerebral ischemia and induce brain ischemic tolerance through the regulation of HIF-1α expression.
Citations
Citations to this article as recorded by
Seroprevalence of latent toxoplasmosis and its association with clinical outcomes in patients with acute ischemic stroke; a case-control study in northeastern Iran Amirali Ghahremani, Hasan Namdar Ahmadabad, Reza shafiei Experimental Parasitology.2025; 276: 109003. CrossRef
Chinese edible frogs, Hoplobatrachus rugulosus, were examined to estimate the potential risks of human gnathostomiasis and sparganosis in Myanmar. A total of 20 frogs were purchased in a local market of Yangon and examined with naked eyes and the artificial digestion method after skin peeling in June 2018 and June 2019. Larvae of gnathostomes and Spirometra (=spargana) were detected in 15 (75.0%) and 15 (75.0%) frogs with average intensities of 10.5 and 6.3 larvae per infected frog, respectively. Gnathostome larvae were 2.75-3.80 (av. 3.30) mm long and 0.29-0.36 (0.33) mm wide. They had a characteristic head bulb with 4 rows of hooklets, a muscular long esophagus, and 2 pairs of cervical sac. The mean number of hooklets were 41, 44, 47, and 50 on the 1st, 2nd, 3rd, and 4th row, respectively. Collected spargana were actively moving, particularly with the scolex part, and have ivory-white color and variable in size. Conclusively, it has been first confirmed that Chinese edible frogs, H. rugulosus, are highly infected with larval gnathostomes and spargana in this study. Consuming these frogs is considered a potential risk of human gnathostomiasis and sparganosis in Myanmar.
Citations
Citations to this article as recorded by
A Global Review of the Zoonotic Potential and Disease Risks of Amphibian Parasites in Bullfrog Aquaculture Meiqi Weng, Xinhua Liu, Chenxi Zhang, Rui Shu, Andrew Wang, Haotian Zhang, Xingqiang Wang, Huirong Yang, Jinyong Zhang Reviews in Aquaculture.2025;[Epub] CrossRef
Parasitic helminths of alien invasive anurans in Butuan City, Northeastern Mindanao, Philippines CA. V. Torralba, E. F. Gamalinda, L. A. Estaño Helminthologia.2023; 60(4): 385. CrossRef
Echinostoma mekongi: Discovery of Its Metacercarial Stage in Snails, Filopaludina martensi cambodjensis, in Pursat Province, Cambodia Jong-Yil Chai, Woon-Mok Sohn, Jaeeun Cho, Bong-Kwang Jung, Taehee Chang, Keon Hoon Lee, Virak Khieu, Rekol Huy The Korean Journal of Parasitology.2021; 59(1): 47. CrossRef
Detection of Gnathostoma spinigerum Advanced 3rd-Stage Larvae in the Chinese Edible Frog, Hoplobatrachus rugulosus, from Local Markets in Phnom Penh, Cambodia Woon-Mok Sohn, Bong-Kwang Jung, Sooji Hong, Seungwan Ryoo, Keon Hoon Lee, Virak Khieu, Jong-Yil Chai The Korean Journal of Parasitology.2021; 59(5): 519. CrossRef
Larval Gnathostomes and Zoonotic Trematode Metacercariae in Fish from a Local Market in Yangon City, Myanmar Jong-Yil Chai, Bong-Kwang Jung, Keon Hoon Lee, Jin-Youp Ryu, Hyeon-Seung Kim, Sung-Jong Hong, Thi Thi Htoon, Htay Htay Tin, Byoung-Kuk Na, Woon-Mok Sohn The Korean Journal of Parasitology.2020; 58(6): 701. CrossRef
Tegumental and excretory-secretory proteins are reported as diagnostic antigens for human opisthorchiasis. Rhophilin associated tail protein1-like (OvROPN1L) protein of Opisthorchis viverrini sperm tail showed potential as a diagnostic antigen. The OvROPN1L recombinant fragments were assayed for diagnostic antigenicity for human opisthorchiasis using indirect ELISA. The strongest antigenic region was a N-terminus peptide of M1 - P56. One synthetic peptide (P1, L3-Q13) of this region showed the highest antigenicity to opisthorchiasis. Sera from other parasitic infections including Strongyloides stercoralis, hookworm, Taenia spp, minute intestinal flukes, Paragonimus spp showed lower reactivity to P1. Peptide P1 is located in the disordered N-terminus of ROPN1L supporting its suitability as linear epitope. In the Platyhelminthes the N-terminal sequence of ROPN1L is diverging with taxonomic distance further suggesting that peptide P1 has potential as diagnostic tool in the genus Opisthorchis/Clonorchis. It should be further evaluated in combination with peptides derived from other O. viverrini antigens to increase its diagnostic power.
Citations
Citations to this article as recorded by
Production and immunological characterization of the novel single-chain variable fragment (scFv) antibodies against the epitopes on Opisthorchis viverrini cathepsin F (OvCatF) Pongsakorn Martviset, Jeeraphong Thanongsaksrikul, Amornrat Geadkaew-Krenc, Salisa Chaimon, Kantaphon Glab-ampai, Wanlapa Chaibangyang, Phornphan Sornchuer, Potjanee Srimanote, Jittiporn Ruangtong, Parisa Prathaphan, Tonkla Taechadamrongtham, Nattaya Toru Acta Tropica.2024; 254: 107199. CrossRef
Investigation of a Serine Protease Inhibitor Active in the Infectious Stage of the Human Liver Fluke Opisthorchis viverrini Rosnanee Salang, Wansika Phadungsil, Amornrat Geadkaew-Krenc, Rudi Grams Pathogens.2024; 13(8): 678. CrossRef
Production and Immunological Characterization of scFv Specific to Epitope of Opisthorchis viverrini Rhophilin-Associated Tail Protein 1-like (OvROPN1L) Amornrat Geadkaew-Krenc, Dawid Krenc, Jeeraphong Thanongsaksrikul, Rudi Grams, Wansika Phadungsil, Kittirat Glab-ampai, Pathanin Chantree, Pongsakorn Martviset Tropical Medicine and Infectious Disease.2023; 8(3): 160. CrossRef
Cystatins from the Human Liver Fluke Opisthorchis viverrini: Molecular Characterization and Functional Analysis Amornrat Geadkaew-Krenc, Rudi Grams, Sinee Siricoon, Nanthawat Kosa, Dawid Krenc, Wansika Phadungsil, Pongsakorn Martviset Pathogens.2023; 12(7): 949. CrossRef
Novel recombinant proteins and peptides from Clonorchis sinensis and Opisthorchis viverrini for liver fluke exposure ELISA Sumathy Mohan, Mohan Natarajan, John G. Bruno Biochemistry and Biophysics Reports.2023; 35: 101516. CrossRef
Screening of sperm antigen epitopes by phage display technique and its preliminary clinical application Jin-Chun Lu, Yan-Mei Ge, Yuan-Hua Xu, Shan-Shan Tang, Yuan-Jiao Liang Basic and Clinical Andrology.2022;[Epub] CrossRef
First
Prev
