Parasites, Hosts and Diseases

"Gymnophalloides seoi"

Original Article

Increased Intestinal Epithelial Cell Turnover and Intestinal Motility in Gymnophalloides seoi-Infected C57BL/6 Mice: Sang Hyub Lee, Bong-Kwang Jung, Jae-Hwan Park, Eun-Hee Shin, Jong-Yil Chai; Korean J Parasitol 2014;52(3):273-280.
Published online June 26, 2014; DOI: https://doi.org/10.3347/kjp.2014.52.3.273

Abstract
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The changing patterns of goblet cell hyperplasia, intestinal epithelial cell turnover, and intestinal motility were studied in ICR and C57BL/6 mice infected with Gymnophalloides seoi (Digenea: Gymnophallidae). Whereas ICR mice retained G. seoi worms until day 7 post-infection (PI), C57BL/6 mice showed a rapid worm expulsion within day 3 PI. Immunosuppression with Depo-Medrol significantly delayed the worm expulsion in C57BL/6 mice. Goblet cell counts were increased in both strains of mice, peaking at day 1 PI in C57BL/6 mice and slowly increasing until day 7 PI in ICR mice. In C57BL/6 mice infected with G. seoi, newly proliferating intestinal epithelial cells were remarkably increased in the crypt, and the increase was the highest at day 1 PI. However, in ICR mice, newly proliferating intestinal epithelial cells increased slowly from day 1 to day 7 PI. Intestinal motility was increased in G. seoi-infected mice, and its chronological pattern was highly correlated with the worm load in both strains of mice. Meanwhile, immunosuppression of C57BL/6 mice abrogated the goblet cell proliferation, reduced the epithelial cell proliferation, and suppressed the intestinal motility. Goblet cell hyperplasia, increased intestinal epithelial cell turnover, and increased intestinal motility should be important mucosal defense mechanisms in G. seoi-infected C57BL/6 mice.

Citations

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Differential alterations in the small intestine epithelial cell turnover during acute and chronic infection with Echinostoma caproni (Trematoda)
Alba Cortés, Carla Muñoz-Antoli, Carla Martín-Grau, J. Guillermo Esteban, Richard K. Grencis, Rafael Toledo
Parasites & Vectors.2015;[Epub] CrossRef

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Brief Communications

STAT6 Expression and IL-13 Production in Association with Goblet Cell Hyperplasia and Worm Expulsion of Gymnophalloides seoi from C57BL/6 Mice: Jin-Joo Lee, Donghee Kim, Kyoung-Ho Pyo, Min-Ki Kim, Hyo-Jin Kim, Jong-Yil Chai, Eun-Hee Shin; Korean J Parasitol 2013;51(5):589-594.
Published online October 31, 2013; DOI: https://doi.org/10.3347/kjp.2013.51.5.589

Abstract
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In intestinal helminth infections, Th2 immune respones are generally associated with mucin secretion for worm expulsion from the host intestine. In particular, IL-4 and IL-13 are the important cytokines related with intestinal mucus production via STAT6 signalling in nematode infections. However, this perspective has never been studied in Gymnophalloides seoi infection. The present study aimed to observe the STAT6 signalling and cytokine responses in C57BL/6 mice, a mouse strain resistant to infection with this trematode. The results showed that worm expulsion occurred actively during days 1-2 post-infection (PI), when goblet cells began to proliferate in the small intestine. The STAT6 gene expression in the mouse spleen became remarkable from day 2 PI. Moreover, G. seoi infection induced a significant increase of IL-13 from day 4 PI in the spleen of infected mice. Our results suggested that goblet cell hyperplasia and worm expulsion in G. seoi-infected mice should be induced by STAT6 signalling, in which IL-13 may be involved as a dominant triggering cytokine.

Citations

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Jenny K. Gustafsson, Gunnar C. Hansson
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Franziska Bayer, Olga Dremova, My Phung Khuu, Könül Mammadova, Giulia Pontarollo, Klytaimnistra Kiouptsi, Natalia Soshnikova, Helen Louise May-Simera, Kristina Endres, Christoph Reinhardt
Nutrients.2021; 13(7): 2198. CrossRef
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Songwei Yang, Min Yu
Journal of Inflammation Research.2021; Volume 14: 3171. CrossRef
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Mingming Zhang, Chenchen Wu
Bioscience Reports.2020;[Epub] CrossRef
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Hongbo Yi, Denghu Jiang, Lin Zhang, Haitao Xiong, Feifei Han, Yizhen Wang
International Immunopharmacology.2016; 36: 199. CrossRef
Increased Intestinal Epithelial Cell Turnover and Intestinal Motility in Gymnophalloides seoi-Infected C57BL/6 Mice
Sang Hyub Lee, Bong-Kwang Jung, Jae-Hwan Park, Eun-Hee Shin, Jong-Yil Chai
The Korean Journal of Parasitology.2014; 52(3): 273. CrossRef

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Intestinal Helminth Infections in Feral Cats and a Raccoon Dog on Aphaedo Island, Shinan-gun, with a Special Note on Gymnophalloides seoi Infection in Cats: Eun-Hee Shin, Jae-Hwan Park, Sang-Mee Guk, Jae-Lip Kim, Jong-Yil Chai; Korean J Parasitol 2009;47(2):189-191.
Published online May 26, 2009; DOI: https://doi.org/10.3347/kjp.2009.47.2.189

Abstract
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Four feral cats and a raccoon dog purchased from a local collector on Aphaedo Island, Shinan-gun, where human Gymnophalloides seoi infections are known to be prevalent, were examined for their intestinal helminth parasites. From 2 of 4 cats, a total of 310 adult G. seoi specimens were recovered. Other helminths detected in cats included Heterophyes nocens (1,527 specimens), Pygidiopsis summa (131), Stictodora fuscata (4), Acanthotrema felis (2), Spirometra erinacei (15), toxocarids (4), and a hookworm (1). A raccoon dog was found to be infected with a species of echinostome (55), hookworms (7), toxocarids (3), P. summa (3), and S. erinacei (1). No G. seoi was found in the raccoon dog. The results indicate that feral cats and raccoon dogs on Aphaedo are natural definitive hosts for intestinal trematodes and cestodes, including G. seoi, H. nocens, and S. erinacei. It has been first confirmed that cats, a mammalian species other than humans, play the role of a natural definitive host for G. seoi on Aphaedo Island.

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Heliyon.2024; 10(9): e30059. CrossRef
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The Korean Journal of Parasitology.2021; 59(1): 83. CrossRef
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Heon Woo Lee, Eui Ju Hong, Hyeon Cheol Kim, Si Yun Ryu, Bae Keun Park
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Jong-Yil Chai, Bong-Kwang Jung
Acta Tropica.2020; 201: 105210. CrossRef
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Taehee Chang, Bong-Kwang Jung, Hyejoo Shin, Sooji Hong, Jeonggyu Lee, Deok-Gyu Kim, Laddawan Patarwut, Woon-Mok Sohn, Jong-Yil Chai
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Ji-Hyeon Kim, Kyunghyun Lee, Woon-Mok Sohn, Ha-Young Kim, Yu-Ran Lee, Eun-Jin Choi, ByungJae So, Ji-Youl Jung
The Korean Journal of Parasitology.2019; 57(1): 17. CrossRef
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Khaled Mohamed El-Dakhly, Amany Samir Aboshinaf, Asmaa Alaa Kamel
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Umanets Alexander, Chae-Wong Lim, Bumseok Kim, Eui-Ju Hong, Hyeon-Cheol Kim, Bae-Keun Park
The Korean Journal of Parasitology.2018; 56(6): 567. CrossRef
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Jong-Yil Chai, Bong-Kwang Jung
Food and Waterborne Parasitology.2017; 8-9: 33. CrossRef
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Quan Liu, Ming-Wei Li, Ze-Dong Wang, Guang-Hui Zhao, Xing-Quan Zhu
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Jong-Yil Chai, Jae-Lip Kim, Min Seo
The Korean Journal of Parasitology.2014; 52(3): 291. CrossRef
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Jong-Yil Chai, Young Yil Bahk, Woon-Mok Sohn
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Original Article

A new endemic focus of Gymnophalloides seoi infection on Aphae Island, Shinan-gun, Jeollanam-do: Jae-Hwan Park, Sang-Mee Guk, Eun-Hee Shin, Hyo-Jin Kim, Jae-Lip Kim, Min Seo, Yun-Kyu Park, Jong-Yil Chai; Korean J Parasitol 2007;45(1):39-44.
Published online March 20, 2007; DOI: https://doi.org/10.3347/kjp.2007.45.1.39

Abstract
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A new endemic focus of Gymnophalloides seoi infection has been discovered on Aphae Island (Shinan-gun, Jeollanam-do), Republic of Korea. This area, which is referred to as Bokyong-ri, is a small seashore village located in the northern portion of the island. Fecal samples were collected from a total of 57 residents and examined by the Kato-Katz and formalin-ether sedimentation techniques. Helminth eggs were detected in 37 samples (64.9%); 33 samples were positive for G. seoi eggs (57.9%), 4 for Pygidiopsis summa (7.0%), 13 for other heterophyids (22.8%), 1 for Clonorchis sinensis (1.7%), and 1 for Trichuris trichiura (1.7%). Women (70.4%) revealed higher rates of G. seoi infection than did men (46.7%), and individuals older than 50 years of age also evidenced higher rates of G. seoi infection than in other age groups (P< 0.05). In worm collection from 13 G. seoi egg positive cases, G. seoi (total 86,558 specimens), Heterophyes nocens (278), Stictodora sp. (10), Heterophyopsis continua (3), P. summa (3), and unidentified flukes (42) were collected. Oysters, the source of G. seoi infection, were collected from an area proximal to the village and 50 were examined for metacercariae; 47 (94%) were found infected and the observed metacercarial density was 9.5 ± 8.9 per oyster. The results of this study indicate that Bokyong-ri is a new endemic area of G. seoi infection, with high rates of infection in humans and oysters.

Citations

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Survey of Gymnophalloides seoi Metacercariae in Natural and Cultured Oysters from Several Western Coastal Areas, Korea
Taehee Chang, Bong-Kwang Jung, Hyemi Song, Jaeeun Cho, Sooji Hong, Keon-Hoon Lee, Eui-Hyug Hoang, Jisu Kang, Jini Lim, Hana Lee, Jong-Yil Chai
The Korean Journal of Parasitology.2019; 57(6): 705. CrossRef
Pygidiopsis summa (Digenea: Heterophyidae): Status of Metacercarial Infection in Mullets from Coastal Areas in the Republic of Korea
Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Won-Ja Lee, Mi-Yeoun Park, Soon-Won Lee, Seung-Bong Choi, Beom-Nyung Huh, Won-Seok Seok
The Korean Journal of Parasitology.2016; 54(4): 497. CrossRef
Korean molluscs as auxiliary hosts for parasites: A study of implications for pathogen transmission in a changing climate
Gab-Man Park
The Korean Journal of Malacology.2012; 28(1): 13. CrossRef
Emerging Parasitic Diseases in Korea
Jong-Yil Chai
Journal of the Korean Medical Association.2007; 50(11): 946. CrossRef

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Case Report

A case of colonic lymphoid tissue invasion by Gymnophalloides seoi in a Korean man: Min Seo, Hokyung Chun, Geunghwan Ahn, Kee-Taek Jang, Sang-Mee Guk, Jong-Yil Chai; Korean J Parasitol 2006;44(1):87-89.
Published online March 20, 2006; DOI: https://doi.org/10.3347/kjp.2006.44.1.87

Abstract
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A 65-year old Korean man, living in Mokpo-city, Jeollanam-do, Republic of Korea, visited a local clinic complaining of right upper quadrant pain and indigestion. At colonoscopy, he was diagnosed as having a carcinoma of the ascending colon, and thus, a palliative right hemicolectomy was performed. Subsequently, an adult fluke of Gymnophalloides seoi was incidentally found in a surgical pathology specimen of the lymph node around the colon. The worm was found to have invaded gut lymphoid tissue, with characteristic morphologies of a large oral sucker, a small ventral sucker, and a ventral pit surrounded by strong muscle fibers. This is the first reported case of mucosal tissue invasion by G. seoi in the human intestinal tract.

Citations

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A potential zoonotic parasite, the digenean Gymnophalloides nacellae, on the Magellanic coast in the Southwestern Atlantic Ocean: its life cycle and geographical distribution
Carmen Gilardoni, Gisele Di Giorgio, Estefanía Bagnato, Susana Pina, Pedro Rodrigues, Florencia Cremonte
Polar Biology.2020; 43(6): 725. CrossRef
Foodborne Intestinal Flukes in Southeast Asia
Jong-Yil Chai, Eun-Hee Shin, Soon-Hyung Lee, Han-Jong Rim
The Korean Journal of Parasitology.2009; 47(Suppl): S69. CrossRef
Emerging Parasitic Diseases in Korea
Jong-Yil Chai
Journal of the Korean Medical Association.2007; 50(11): 946. CrossRef

8,130 View
76 Download
Crossref

Original Article

Prevalence of Gymnophalloides seoi infection in coastal villages of Haenam-gun and Yeongam-gun, Republic of Korea: Sang-Mee Guk, Jae-Hwan Park, Eun-Hee Shin, Jae-Lip Kim, Aifen Lin, Jong-Yil Chai; Korean J Parasitol 2006;44(1):1-5.
Published online March 20, 2006; DOI: https://doi.org/10.3347/kjp.2006.44.1.1

Abstract
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One coastal village in Haenam-gun and two in Yeongam-gun, Jeollanam-do were surveyed for intestinal parasite infections by fecal examination. The egg positive rates of Gymnophalloides seoi were high, 24.1% (14/58) in Haenam-gun and 9.3% (11/118) in Yeongam-gun. The egg positive rates of heterophyids, including Heterophyes nocens, and of Clonorchis sinensis were 10.3% and 6.9% in Haenam-gun, and 14.4% and 8.5% in Yeongam-gun, respectively. After praziquantel treatment and purgation, a total of 37,761 fluke specimens were recovered from 17 patients; 11 in Haenam-gun and 6 in Yeongam-gun. Gymnophalloides seoi was the most commonly recovered species, with 37,489 specimens in total (2,205 per person). Other recovered flukes included Heterophyes nocens, Stictodora fuscata, Heterophyopsis continua, Pygidiopsis summa, and undetermined species. These results indicate that the areas surveyed are new endemic foci of G. seoi.

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Polar Biology.2020; 43(6): 725. CrossRef
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Taehee Chang, Bong-Kwang Jung, Hyemi Song, Jaeeun Cho, Sooji Hong, Keon-Hoon Lee, Eui-Hyug Hoang, Jisu Kang, Jini Lim, Hana Lee, Jong-Yil Chai
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Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Won-Ja Lee, Mi-Yeoun Park, Soon-Won Lee, Seung-Bong Choi, Beom-Nyung Huh, Won-Seok Seok
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Eun Jeong Won, Soo Hyun Kim, Seung Jung Kee, Jong Hee Shin, Soon Pal Suh, Jong Yil Chai, Dong Wook Ryang, Myung Geun Shin, Mark Spigelman
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Young-Il Lee, Ok-Sik Chung, Min Seo
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Increased Intestinal Epithelial Cell Turnover and Intestinal Motility in Gymnophalloides seoi-Infected C57BL/6 Mice
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The Korean Journal of Parasitology.2014; 52(3): 273. CrossRef
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Jong-Yil Chai, Eun-Hee Shin, Soon-Hyung Lee, Han-Jong Rim
The Korean Journal of Parasitology.2009; 47(Suppl): S69. CrossRef
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Eun-Hee Shin, Sang-Mee Guk, Hyo-Jin Kim, Soon-Hyung Lee, Jong-Yil Chai
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A new endemic focus of Heterophyes nocens and other heterophyid infections in a coastal area of Gangjin-gun, Jeollanam-do
Jae-Hwan Park, Jae-Lip Kim, Eun-Hee Shin, Sang-Mee Guk, Yun-Kyu Park, Jong-Yil Chai
The Korean Journal of Parasitology.2007; 45(1): 33. CrossRef

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Mini Review

A review of Gymnophalloides seoi (Digenea: Gymnophallidae) and human infections in the Republic of Korea: Soon-Hyung Lee, Jong-Yil Chai; Korean J Parasitol 2001;39(2):85-118.
Published online June 30, 2002; DOI: https://doi.org/10.3347/kjp.2001.39.2.85

Abstract
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Studies on Gymnophalloides seoi (Digenea: Gymnophallidae) and human infections are briefly reviewed. This minute intestinal fluke was first discovered from a Korean woman suffering from acute pancreatitis and gastrointestinal troubles. It was described as a new species by Lee, Chai and Hong in 1993. The southwestern coastal village where the patient resided was found to be a highly endemic area, and additional endemic areas have been identified. The parasite is very small, 0.33-0.50 mm long and 0.23-0.33 mm wide, and characterized by the presence of a ventral pit. The first intermediate host remains unknown, but the second intermediate host has been found to be the oyster Crassostrea gigas. Man and the Palearctic oystercatcher Haematopus ostralegus have been shown to be natural definitive hosts, and wading birds including the Kentish plover Charadrius alexandrinus are highly susceptible to experimental infection. Gerbils, hamsters, cats, and several strains of mice were also susceptible laboratory hosts. In experimentally infected mice, the parasites inhabit the small intestine, pinching and sucking the root of villi with their large oral suckers, but they did not invade beyond the mucosa in immunocompetent mice. However, they were found to invade the submucosa in immunosuppressed mice. Human G. seoi infections have been found in at least 25 localities; 23 islands on the Yellow Sea or the South Sea, and 2 western coastal villages. The highest prevalence was found in a village on Aphaedo, Shinan-gun (49% egg positive rate); other areas showed 0.8-25.3% prevalence. Infected people complained of variable degrees of gastrointestinal troubles and indigestion. The infection can be diagnosed by recovery of eggs in the feces; however, an expert is needed to identify the eggs. Praziquantel, 10 mg/kg in single dose, is effective for treatment of human infections. Eating raw oysters in endemic areas should be avoided.

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Intestinal Helminth Infections in Feral Cats and a Raccoon Dog on Aphaedo Island, Shinan-gun, with a Special Note on Gymnophalloides seoi Infection in Cats
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Cd4+ T-cell-dependent Goblet Cell Proliferation and Expulsion of Gymnophalloides seoi from the Intestine of C57bl/6 Mice
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A case of colonic lymphoid tissue invasion by Gymnophalloides seoi in a Korean man
Min Seo, Hokyung Chun, Geunghwan Ahn, Kee-Taek Jang, Sang-Mee Guk, Jong-Yil Chai
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Food-borne Parasitic Diseases
Jong-Yil Chai
Journal of the Korean Medical Association.2004; 47(6): 496. CrossRef
Gymnophalloides seoi: a new human intestinal trematode
Jong-Yil Chai, Min-Ho Choi, Jae-Ran Yu, Soon-Hyung Lee
Trends in Parasitology.2003; 19(3): 109. CrossRef
Role of Intestinal Goblet Cells in the Expulsion of Gymnophalloides seoi From Mice
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Journal of Parasitology.2003; 89(5): 1080. CrossRef
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Jong-Yil Chai, Soon-Hyung Lee
Parasitology International.2002; 51(2): 129. CrossRef

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Original Articles

Intestinal histopathology and in situ postures of Gymnophalloides seoi in experimentally infected mice: Jong-Yil Chai, Hong-Soon Lee, Sung-Jong Hong, Jae Hyung Yoo, Sang-Mee Guk, Min Seo, Min-Ho Choi, Soon-Hyung Lee; Korean J Parasitol 2001;39(1):31-41.
Published online March 31, 2001; DOI: https://doi.org/10.3347/kjp.2001.39.1.31

Abstract
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The intestinal histopathology and in situ postures of Gymnophalloides seoi (Digenea: Gymnophallidae) were studied using C3H/HeN and C57BL/6 mice as experimental hosts; the effects of immunosuppression were also observed. The metacercariae isolated from naturally infected oysters, 300 or 1,000 in number, were infected orally to each mouse, and the mice were killed at days 3-21 post-infection (PI). In immunocompetent (IC) mice, only a small number of flukes were found in the mucosa of the duodenum and jejunum during days 3-7 PI, with their large oral suckers pinching and sucking the root of villi. The intestinal mucosa showed mild villous atrophy, crypt hyperplasia, and inflammations in the villous stroma and crypt, with remarkable goblet cell hyperplasia. These mucosal changes were almost restored after days 14-21 PI. In immunosuppressed (IS) mice, displacement as well as complete loss of villi adjacent to the flukes was frequently encountered, otherwise the histopathology was generally mild, with minimal goblet cell hyperplasia. In these mice, numerous flukes were found, and it seemed that they were actively moving and rotating in situ. Several flukes were found to have invaded into the submucosa, almost facing the serosa. These results indicate that in IC mice the intestinal histopathology caused by G. seoi is generally mild, and the flukes do not penetrate beyond the mucosa, however, in IS mice, the flukes can cause severe destruction of neighboring villi, and some of them invade into the submucosa.

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Foodborne Intestinal Flukes in Southeast Asia
Jong-Yil Chai, Eun-Hee Shin, Soon-Hyung Lee, Han-Jong Rim
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A new endemic focus of Gymnophalloides seoi infection on Aphae Island, Shinan-gun, Jeollanam-do
Jae-Hwan Park, Sang-Mee Guk, Eun-Hee Shin, Hyo-Jin Kim, Jae-Lip Kim, Min Seo, Yun-Kyu Park, Jong-Yil Chai
The Korean Journal of Parasitology.2007; 45(1): 39. CrossRef
A case of colonic lymphoid tissue invasion by Gymnophalloides seoi in a Korean man
Min Seo, Hokyung Chun, Geunghwan Ahn, Kee-Taek Jang, Sang-Mee Guk, Jong-Yil Chai
The Korean Journal of Parasitology.2006; 44(1): 87. CrossRef
Gymnophalloides seoi: a new human intestinal trematode
Jong-Yil Chai, Min-Ho Choi, Jae-Ran Yu, Soon-Hyung Lee
Trends in Parasitology.2003; 19(3): 109. CrossRef
Food-borne intestinal trematode infections in the Republic of Korea
Jong-Yil Chai, Soon-Hyung Lee
Parasitology International.2002; 51(2): 129. CrossRef
A review of Gymnophalloides seoi (Digenea: Gymnophallidae) and human infections in the Republic of Korea
Soon-Hyung Lee, Jong-Yil Chai
The Korean Journal of Parasitology.2001; 39(2): 85. CrossRef

9,318 View
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A nationwide survey of the prevalence of human Gymnophalloides seoi infection on western and southern coastal islands in the Republic of Korea: Jong-Yil Chai, Jae-Hwan Park, Eun-Taek Han, Eun-Hee Shin, Jae-Lip Kim, Kwang-Seon Hong, Han-Jong Rim, Soon-Hyung Lee; Korean J Parasitol 2001;39(1):23-30.
Published online March 31, 2001; DOI: https://doi.org/10.3347/kjp.2001.39.1.23

Abstract
PDF

A nationwide survey was performed to know the distribution and prevalence of human Gymnophalloides seoi infection on western and southern coastal islands in the Republic of Korea. A total of 4,178 fecal specimens were collected from residents on 45 (24 western and 21 southern) islands, and examined by Kato-Katz and formalin-ether sedimentation techniques. Eggs of G. seoi were detected from 160 (3.8%) people living on 22 (13 western and 9 southern) islands. The prevalence varied by the location of islands; higher on western islands than on southern islands. The highest prevalence was found on Amtaedo (25.3%), followed by Cheungdo (25.0%), and Anchwado (20.9%) (Shinan-gun). A little lower prevalence was observed on Munyodo (13.3%), Shinshido (12.9%), and Sonyudo (10.3%) (Kunsan-shi). Of the remaining islands, the regions showing the prevalence greater than 5% included Kohado, Dallido (Mokpo-shi), Pyeongildo, Kogumdo (Wando-gun), and Keogumdo (Kohung-gun). A strong age predilection was noted (p < 0.05); 95% of the infected people were over 40 years old. Females showed a little higher prevalence than males. The results indicate that human G. seoi infection is more widely distributed than previously considered. Nine of 11 islands (excluding the 2 known areas Munyodo and Sunyudo) that showed greater prevalence than 5% are regarded as new endemic foci of G. seoi.

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Prevalence and Density of Digenetic Trematode Metacercariae in Clams and Oysters from Western Coastal Regions of the Republic of Korea
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Min Seo, Adauto Araujo, Karl Reinhard, Jong Yil Chai, Dong Hoon Shin
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Sang Hyub Lee, Bong-Kwang Jung, Jae-Hwan Park, Eun-Hee Shin, Jong-Yil Chai
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Jong-Yil Chai, Eun-Hee Shin, Soon-Hyung Lee, Han-Jong Rim
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Eun-Hee Shin, Sang-Mee Guk, Hyo-Jin Kim, Soon-Hyung Lee, Jong-Yil Chai
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Gymnophalloides seoi Eggs from the Stool of a 17th Century Female Mummy Found in Hadong, Republic of Korea
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A new endemic focus of Gymnophalloides seoi infection on Aphae Island, Shinan-gun, Jeollanam-do
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Sang-Mee Guk, Jae-Hwan Park, Eun-Hee Shin, Jae-Lip Kim, Aifen Lin, Jong-Yil Chai
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A survey of Enterobius vermicularis infection among children on western and southern coastal islands of the Republic of Korea
Jae-Hwan Park, Eun-Taek Han, Won-Hee Kim, Eun-Hee Shin, Sang-Mee Guk, Jae-Lip Kim, Jong-Yil Chai
The Korean Journal of Parasitology.2005; 43(4): 129. CrossRef
Gymnophalloides seoi: a new human intestinal trematode
Jong-Yil Chai, Min-Ho Choi, Jae-Ran Yu, Soon-Hyung Lee
Trends in Parasitology.2003; 19(3): 109. CrossRef
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Jong-Yil Chai, Soon-Hyung Lee
Parasitology International.2002; 51(2): 129. CrossRef
A review of Gymnophalloides seoi (Digenea: Gymnophallidae) and human infections in the Republic of Korea
Soon-Hyung Lee, Jong-Yil Chai
The Korean Journal of Parasitology.2001; 39(2): 85. CrossRef

10,351 View
99 Download
Crossref

Discovery of Gymnophalloides seoi metacercariae in oysters from islands of the West Sea known as the habitats of paleartic oystercatchers: Woon-Mok Sohn, Yong-Suk Ryang, Jong-Yil Chai, Soon-Hyung Lee; Korean J Parasitol 1998;36(3):163-169.
Published online September 30, 1998; DOI: https://doi.org/10.3347/kjp.1998.36.3.163

Abstract
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An epidemiological survey was performed to know the infection status of oysters with Gymnophalloides seoi metacercariae in 7 islands of the West Sea known as the habitat of paleartic oystercatchers, Haematopus ostralegus osculans, in Korea. The surveyed areas were Aphaedo (Shinan-gun, Chollanam-do), Jangjado, Sonyudo and Munyodo (Okdo-myon, Kunsan-shi, Chollabuk-do), Yubudo (Changhang-up, Sochon-gun Chungchongnam-do), and Polumdo and Chumoondo (Sodo-myon, Kangwha-gun. Inchon-shi). The oysters collected from Aphaedo, the known endemic focus, were examined monthly from August 1995 to October 1996 for observation of any seasonal variation of the metacercarial density. The average metacercarial burden was 761-2,077 by month, but the seasonal variation of the metacercarial density was not obvious. A total of 54 metacercariae was detected in 63 oysters collected from Yubudo. Out of 30 oysters from Sonyudo, 25 (83.3%) were infected with 1-66 metacercariae (12.6 in average). All of 50 oysters (100%) from Munyodo were infected with 3-162 metacercariae (53.5 in average). Only 4 metacercariae were detected in 100 oysters from Chumoondo. However, no metacercariae were found in 55 oysters from Jangjado and 50 oysters from Polumdo. From the above results, it was confirmed that G. seoi is still highly prevalent in oysters from Aphaedo, and several islands of the West Sea known as the habitats of paleartic oystercatchers are new endemic areas of this fluke.

Citations

Citations to this article as recorded by

Survey of Gymnophalloides seoi Metacercariae in Natural and Cultured Oysters from Several Western Coastal Areas, Korea
Taehee Chang, Bong-Kwang Jung, Hyemi Song, Jaeeun Cho, Sooji Hong, Keon-Hoon Lee, Eui-Hyug Hoang, Jisu Kang, Jini Lim, Hana Lee, Jong-Yil Chai
The Korean Journal of Parasitology.2019; 57(6): 705. CrossRef
Prevalence and Density of Digenetic Trematode Metacercariae in Clams and Oysters from Western Coastal Regions of the Republic of Korea
Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Won-Ja Lee
The Korean Journal of Parasitology.2017; 55(4): 399. CrossRef
Foodborne Intestinal Flukes in Southeast Asia
Jong-Yil Chai, Eun-Hee Shin, Soon-Hyung Lee, Han-Jong Rim
The Korean Journal of Parasitology.2009; 47(Suppl): S69. CrossRef
A new endemic focus of Gymnophalloides seoi infection on Aphae Island, Shinan-gun, Jeollanam-do
Jae-Hwan Park, Sang-Mee Guk, Eun-Hee Shin, Hyo-Jin Kim, Jae-Lip Kim, Min Seo, Yun-Kyu Park, Jong-Yil Chai
The Korean Journal of Parasitology.2007; 45(1): 39. CrossRef
Gymnophalloides seoi: a new human intestinal trematode
Jong-Yil Chai, Min-Ho Choi, Jae-Ran Yu, Soon-Hyung Lee
Trends in Parasitology.2003; 19(3): 109. CrossRef
Food-borne intestinal trematode infections in the Republic of Korea
Jong-Yil Chai, Soon-Hyung Lee
Parasitology International.2002; 51(2): 129. CrossRef
Intestinal histopathology and in situ postures of Gymnophalloides seoi in experimentally infected mice
Jong-Yil Chai, Hong-Soon Lee, Sung-Jong Hong, Jae Hyung Yoo, Sang-Mee Guk, Min Seo, Min-Ho Choi, Soon-Hyung Lee
The Korean Journal of Parasitology.2001; 39(1): 31. CrossRef
A nationwide survey of the prevalence of human Gymnophalloides seoi infection on western and southern coastal islands in the Republic of Korea
Jong-Yil Chai, Jae-Hwan Park, Eun-Taek Han, Eun-Hee Shin, Jae-Lip Kim, Kwang-Seon Hong, Han-Jong Rim, Soon-Hyung Lee
The Korean Journal of Parasitology.2001; 39(1): 23. CrossRef
A review of Gymnophalloides seoi (Digenea: Gymnophallidae) and human infections in the Republic of Korea
Soon-Hyung Lee, Jong-Yil Chai
The Korean Journal of Parasitology.2001; 39(2): 85. CrossRef