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Mini Review

Sparganosis in the Indian Sub-continent and the Middle East
Yukifumi Nawa, Mio Tanaka, Masahide Yoshikawa
Parasites Hosts Dis 2024;62(3):263-269.
Published online August 26, 2024
DOI: https://doi.org/10.3347/PHD.23126
Sparganosis is one of the common zoonotic diseases caused by infection with the larval plerocercoids (spargana) of the cestode genus Spirometra. While this parasite distributes globally in canine and feline hosts, human infection is predominantly reported in East Asia, especially China, Korea, Japan, and Thailand. Maybe related to the behavior and food culture, this zoonotic disease is rather rare in South Asia to the Middle East. In these areas, sporadic case reports have been appeared mostly in the local medical journals. To draw a solid picture of sparganosis in these non-endemic areas of Asia, we made an extensive literature survey to gather sparganosis cases in the Indian subcontinent and the Middle East.

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  • Case report: Sparganosis in Minervarya pierrei (Dubois, 1975) (Amphibia: Anura: Dicroglossidae), a new host from India
    Neelanjana Saha, Sudheer Kumar Jena, Oindrila Paul, Suman Das, Upasana Bhattacharya, Anjum N. Rizvi, Pratyush P. Mohapatra
    Journal of Parasitic Diseases.2025;[Epub]     CrossRef
  • Deciphering the global genetic structure of Spirometra mansoni and S. erinaceieuropaei based on 28S ribosomal RNA: Insights into taxonomical revaluation and population dynamics
    Anil Kumar Nehra, Rasmita Panda, Prem Sagar Maurya, Ansu Kumari, Aman Dev Moudgil
    Parasitology Research.2025;[Epub]     CrossRef
  • 3,309 View
  • 91 Download
  • 2 Web of Science
  • Crossref

Original Article

Intestinal Parasitosis in Relation to Anti-Retroviral Therapy, CD4+ T-cell Count and Diarrhea in HIV Patients
Shehla Khalil, Bijay Ranjan Mirdha, Sanjeev Sinha, Ashutosh Panda, Yogita Singh, Anju Joseph, Manorama Deb
Korean J Parasitol 2015;53(6):705-712.
Published online December 31, 2015
DOI: https://doi.org/10.3347/kjp.2015.53.6.705
Intestinal parasitic infections are one of the major causes of diarrhea in human immunodeficiency virus (HIV) seropositive individuals. Antiretroviral therapy has markedly reduced the incidence of many opportunistic infections, but parasite-related diarrhea still remains frequent and often underestimated especially in developing countries. The present hospital-based study was conducted to determine the spectrum of intestinal parasitosis in adult HIV/AIDS (acquired immunodeficiency syndrome) patients with or without diarrhea with the levels of CD4+ T-cell counts. A total of 400 individuals were enrolled and were screened for intestinal parasitosis. Of these study population, 200 were HIV seropositives, and the remaining 200 were HIV uninfected individuals with or without diarrhea. Intestinal parasites were identified by using microscopy as well as PCR assay. A total of 130 (32.5%) out of 400 patients were positive for any kinds of intestinal parasites. The cumulative number of parasite positive patients was 152 due to multiple infections. A significant association of Cryptosporidium (P<0.001) was detected among individuals with CD4+ T-cell counts less than 200 cells/μl.

Citations

Citations to this article as recorded by  Crossref logo
  • The Global Prevalence of and Factors Associated with Parasitic Coinfection in People Living with Viruses: A Systematic Review and Meta-Analysis
    Yan Ge, Huaman Liu, Ningjun Ren, Abdul Qadeer, Ian Kim B. Tabios, Ian Kendrich C. Fontanilla, Lydia R. Leonardo, Banchob Sripa, Guofeng Cheng
    Pathogens.2025; 14(6): 534.     CrossRef
  • Unveiling the hidden threat: prevalence of Enterocytozoon bieneusi and other intestinal parasitic infections among organ transplant recipients in Southern Iran
    Mohammad Hossein Motazedian, Leila Morabi, Shahrokh Ezzatzadegan Jahromi, Mojtaba Shafiekhani, Saeed Shahabi, Hamed Nikoupour Dailami, Siavash Gholami, Bahador Sarkari
    Gut Pathogens.2025;[Epub]     CrossRef
  • Worldwide Epidemiology of Cyclospora cayetanensis in HIV/AIDS Patients: A Systematic Review and Meta-Analysis
    Farzad Mahdavi, Ali Pouryousef, Mohammad Reza Mohammadi, Kambiz Karimi, Asma Mousivand, Farajolah Maleki, Ali Asghari, Mina Mamizadeh
    Acta Parasitologica.2025;[Epub]     CrossRef
  • Prevalence, Antibiotic Susceptibility Pattern, and Associated Factors of Enteric Bacterial Pathogens Among HIV Infected Patients with Diarrhea Attending the ART Clinic of Dilla University Referral Hospital, Southern Ethiopia
    Asaye Mitiku, Zerihin Solomon, Berhanu Gidisa, Kasie Gebeyhu, Haymanot Tewabe, Demissew Shenkute, Melkayehu Kassa, Addisu Gize
    Infection and Drug Resistance.2023; Volume 16: 4227.     CrossRef
  • Worldwide prevalence of emerging parasite Blastocystis in immunocompromised patients: A systematic review and meta-analysis
    Zohreh Khorshidvand, Salman Khazaei, MohamadReza Amiri, Heshmatollah Taherkhani, Asad Mirzaei
    Microbial Pathogenesis.2021; 152: 104615.     CrossRef
  • Prevalence of Intestinal Coccidiosis Among Patients Living with the Human Immunodeficiency Virus in Abidjan (Côte d'Ivoire)
    N&#;Docho Assi Fiacr, Tuo Karim, N&#;Guessan Tiacoh Lan, Kassi Kondo Fulg, Koffi Attoungbr&eacu Clé, Fofana Mamery, Kouamé Amani Casi, Messou Kouassi Eu, Assoua Messou Ani, Bialé Marina Datcho-Gou, Kragbé Daugbley G, N&#;Guetta Essan Jean, Oyebi Mukayila,
    Research Journal of Parasitology.2021; 16(1): 9.     CrossRef
  • Association between Blastocystis sp. infection and immunocompromised patients: a systematic review and meta-analysis
    Ali Asghari, Zeinab Sadeghipour, Soheil Hassanipour, Zahra Abbasali, Hasan Ebrahimzadeh-Parikhani, Masoud Hashemzaei, Vahid Alimardani, Gholamreza Hatam
    Environmental Science and Pollution Research.2021; 28(43): 60308.     CrossRef
  • Global prevalence and associated risk factors of diarrheagenic Giardia duodenalis in HIV/AIDS patients: A systematic review and meta-analysis
    Farzad Mahdavi, Morteza Shams, Alireza Sadrebazzaz, Laya Shamsi, Mostafa Omidian, Ali Asghari, Soheil Hassanipour, Amir Masoud Salemi
    Microbial Pathogenesis.2021; 160: 105202.     CrossRef
  • The Coexistence of Blastocystis spp. in Humans, Animals and Environmental Sources from 2010–2021 in Asia
    Adedolapo Aminat Rauff-Adedotun, Farah Haziqah Meor Termizi, Nurshafarina Shaari, Ii Li Lee
    Biology.2021; 10(10): 990.     CrossRef
  • High carriage rate of intestinal parasites among asymptomatic HIV-seropositive individuals on antiretroviral therapy attending the tertiary care hospital in Varanasi, India
    Manish Kumar Purbey, Aradhana Singh, Simmi Kumari, Tuhina Banerjee
    Indian Journal of Sexually Transmitted Diseases and AIDS.2021; 42(2): 101.     CrossRef
  • Intestinal Parasitosis and its Association with CD4+ T Cell Count and Viral Load among People Living with HIV in Parasite Endemic Settings of Northwest Ethiopia
    Eseye Dereb, Markos Negash, Takele Teklu, Debasu Damtie, Aberham Abere, Firehiwot Kebede, Yalemwork Ewnetu, Eyuel Kasa
    HIV/AIDS - Research and Palliative Care.2021; Volume 13: 1055.     CrossRef
  • Opportunistic parasitic infections in patients with human immunodeficiency virus/acquired immunodeficiency syndrome: A review
    D. A. Laksemi, L. T. Suwanti, M. Mufasirin, K. Suastika, M. Sudarmaja
    Veterinary World.2020; 13(4): 716.     CrossRef
  • Prevalence of enteric bacteria and enteroparasites in human immunodeficiency virus-infected individuals with diarrhoea attending antiretroviral treatment clinic, Arba Minch General Hospital, southern Ethiopia
    A.A. Ayele, D. Tadesse, A. Manilal, T. Yohanes, M. Seid, M. Shewangizaw Mekuria
    New Microbes and New Infections.2020; 38: 100789.     CrossRef
  • Intestinal parasitic infections and associated factors among people living with HIV/AIDS in Ethiopia: A systematic review and meta-analysis
    Adam Wondmieneh, Getnet Gedefaw, Birhan Alemnew, Addisu Getie, Melaku Bimerew, Asmamaw Demis, Francesco Di Gennaro
    PLOS ONE.2020; 15(12): e0244887.     CrossRef
  • Cryptosporidiosis in HIV-positive patients and related risk factors: A systematic review and meta-analysis
    Ehsan Ahmadpour, Hanie Safarpour, Lihua Xiao, Mehdi Zarean, Kareem Hatam-Nahavandi, Aleksandra Barac, Stephane Picot, Mohammad Taghi Rahimi, Salvatore Rubino, Mahmoud Mahami-Oskouei, Adel Spotin, Sanam Nami, Hossein Bannazadeh Baghi
    Parasite.2020; 27: 27.     CrossRef
  • Prevalence of Cryptosporidium, microsporidia and Isospora infection in HIV-infected people: a global systematic review and meta-analysis
    Ze-Dong Wang, Quan Liu, Huan-Huan Liu, Shuang Li, Li Zhang, Yong-Kun Zhao, Xing-Quan Zhu
    Parasites & Vectors.2018;[Epub]     CrossRef
  • Escherichia�coli O101‑induced diarrhea develops gut microbial dysbiosis in rats
    Xiangwan Sun, Ying Gao, Xin Wang, Ge Hu, Yun Wang, Bo Feng, Yanxin Hu, Xiang Mu, Ying Zhang, Hong Dong
    Experimental and Therapeutic Medicine.2018;[Epub]     CrossRef
  • HIV and diarrhoea: what is new?
    Clare Logan, Mike B.J. Beadsworth, Nick J. Beeching
    Current Opinion in Infectious Diseases.2016; 29(5): 486.     CrossRef
  • 14,092 View
  • 185 Download
  • 20 Web of Science
  • Crossref

Brief Communication

Molecular Characterization of Gastrothylax crumenifer (Platyhelminthes: Gastrothylacidae) from Goats in the Western Part of India by LSU of Nuclear Ribosomal DNA
Ashwani Kumar, Anshu Chaudhary, Chandni Verma, Hridaya Shanker Singh
Korean J Parasitol 2014;52(6):701-705.
Published online December 23, 2014
DOI: https://doi.org/10.3347/kjp.2014.52.6.701

The rumen parasite, Gastrothylax crumenifer (Platyhelminthes: Gastrothylacidae), is a highly pathogenic trematode parasite of goat (Capra hircus). It sucks blood that causes acute disease like anemia, and severe economic losses occur due to morbidity and mortality of the ruminant infected by these worms. The study of these rumen paramphistomes, their infection, and public health importance remains unclear in India especially in the western part of state Uttar Pradesh (U.P.), Meerut, India, where the goat meat consumption is very high. This paper provides the molecular characterization of G. crumenifer recovered from the rumen of Capra hircus from Meerut, U.P., India by the partial sequence of 28S rDNA. Nucleotide sequence similarity searching on BLAST of 28S rDNA from parasites showed the highest identity with those of G. crumenifer from the same host Capra hircus. This is the first report of molecular identification of G. crumenifer from this part of India.

Citations

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  • A Universal Approach to Molecular Identification of Rumen Fluke Species Across Hosts, Continents, and Sample Types
    Gillian Mitchell, Ruth N. Zadoks, Philip J. Skuce
    Frontiers in Veterinary Science.2021;[Epub]     CrossRef
  • Rumen fluke, Fischoederius elongatus (Trematoda: Gastrothylacidae): Preliminary investigation of suitable conditions for egg hatching
    Sirapat Nak-on, Thapana Chontananarth
    Veterinary Parasitology.2020; 282: 109135.     CrossRef
  • Incidence of amphistome infection in sheep from Mhow, Madhya Pradesh
    D. K. Bansal, V. Agrawal, A. K. Jayraw, U. K. Garg, G. P Jatav, N. Jamra, Nidhi Singh
    Journal of Parasitic Diseases.2018; 42(1): 19.     CrossRef
  • First genetic evidence for the presence of the rumen fluke Paramphistomum epiclitum in Pakistan
    Qasim Ali, Imran Rashid, Muhammad Zubair Shabbir, Haroon Akbar, Kashif Shahzad, Kamran Ashraf, Neil Sargison, Umer Chaudhry
    Parasitology International.2018; 67(5): 533.     CrossRef
  • 11,083 View
  • 102 Download
  • 3 Web of Science
  • Crossref

Original Article

Prevalence and Clinical Manifestations of Malaria in Aligarh, India
Umm-e Asma, Farha Taufiq, Wajihullah Khan
Korean J Parasitol 2014;52(6):621-629.
Published online December 23, 2014
DOI: https://doi.org/10.3347/kjp.2014.52.6.621

Malaria is one of the most widespread infectious diseases of tropical countries with an estimated 207 million cases globally. In India, there are endemic pockets of this disease, including Aligarh. Hundreds of Plasmodium falciparum and P. vivax cases with severe pathological conditions are recorded every year in this district. The aim of this study is to find out changes in liver enzymes and kidney markers. Specific diagnosis for P. falciparum and P. vivax was made by microscopic examination of Giemsa stained slides. Clinical symptoms were observed in both of these infections. Liver enzymes, such as AST, ALT, and ALP, and kidney function markers, such as creatinine and urea, were estimated by standard biochemical techniques. In Aligarh district, P. vivax, P. falciparum, and mixed infections were 64%, 34%, and 2%, respectively. In case of P. falciparum infection, the incidences of anemia, splenomegaly, renal failure, jaundice, and neurological sequelae were higher compared to those in P. vivax infection. Recrudescence and relapse rates were 18% and 20% in P. falciparum and P. vivax infections, respectively. Liver dysfunctions and renal failures were more common in P. falciparum patients, particularly in elderly patients. Artesunate derivatives must, therefore, be introduced for the treatment of P. falciparum as they resist to chloroquine as well as sulfadoxine-pyrimethamine combinations.

Citations

Citations to this article as recorded by  Crossref logo
  • Challenges of diagnosing severe malaria with complications in adult patients: a case report
    Rika Bur, Erni Juwita Nelwan, Ira Danasasmita, Gardian Lukman Hakim, Syukrini Bahri, Febby Elvanesa Sandra Dewi, Rana Zara Athaya, Leonard Nainggolan
    Tropical Diseases, Travel Medicine and Vaccines.2024;[Epub]     CrossRef
  • Genome-wide liver transcriptomic profiling of a malaria mouse model reveals disturbed immune and metabolic responses
    Xueyan Hu, Jie Zhao, Junhui Zhao, Ence Yang, Mozhi Jia
    Parasites & Vectors.2023;[Epub]     CrossRef
  • Clinical profile and severity of Plasmodium vivax and falciparum malaria in hospitalized children from North India
    Venkatesh Badugu, Bablu Kumar Gaur, Baljeet Maini
    Journal of Vector Borne Diseases.2023; 60(3): 252.     CrossRef
  • Antimalarial activity of solvent fractions of a leaf of Eucalyptus globulus labill against Plasmodium berghei infected mice
    Mihret Ayalew, Seyfe Asrade Atnafie, Azmeraw Bekele
    BMC Complementary Medicine and Therapies.2022;[Epub]     CrossRef
  • Predictors of treatment failures of plasmodium falciparum malaria in Vietnam: a 4-year single‐centre retrospective study
    Minh Cuong Duong, Oanh Kieu Nguyet Pham, Phong Thanh Nguyen, Van Vinh Chau Nguyen, Phu Hoan Nguyen
    Malaria Journal.2021;[Epub]     CrossRef
  • Clinical profile of malaria at a tertiary care teaching hospital in North India
    Ritu Karoli, Shobhit Shakya, Nikhil Gupta, Vineeta Mittal, Anil Kumar Upadhyay
    Tropical Parasitology.2021; 11(1): 25.     CrossRef
  • Anti-Malarial and Anti-Lipid Peroxidation Activities of Deferiprone-Resveratrol Hybrid in Plasmodium berghei-Infected Mice
    Hataichanok Chuljerm, Supawadee Maneekesorn, Voravuth Somsak, Yongmin Ma, Somdet Srichairatanakool, Pimpisid Koonyosying
    Biology.2021; 10(9): 911.     CrossRef
  • Clinical features and haematological parameters among malaria patients in Mangaluru city area in the southwestern coastal region of India
    Kishore Punnath, Kiran K. Dayanand, Valleesha N. Chandrashekar, Rajeshwara N. Achur, Srinivas B. Kakkilaya, Susanta K. Ghosh, Benudhar Mukhi, Vishal Midya, Suchetha N. Kumari, D. Channe Gowda
    Parasitology Research.2020; 119(3): 1043.     CrossRef
  • A micro-epidemiological report on the unstable transmission of malaria in Aligarh, India
    Sana Aqeel, Ansari Naheda, Adil Raza, Wajihullah Khan
    Parasite Epidemiology and Control.2020; 11: e00161.     CrossRef
  • Phenotypic characterization of acute headache attributed to SARS-CoV-2: An ICHD-3 validation study on 106 hospitalized patients
    Javier Trigo López, David García-Azorín, Álvaro Planchuelo-Gómez, Cristina García-Iglesias, Carlos Dueñas-Gutiérrez, Ángel L Guerrero
    Cephalalgia.2020; 40(13): 1432.     CrossRef
  • Comparative study of clinical presentation and hematological indices in hospitalized sickle cell patients with severe Plasmodium falciparum malaria
    Prasanta Purohit, Pradeep K. Mohanty, Siris Patel, Padmalaya Das, Jogeswar Panigrahi, Kishalaya Das
    Journal of Infection and Public Health.2018; 11(3): 321.     CrossRef
  • Severe thrombocytopaenia in patients with vivax malaria compared to falciparum malaria: a systematic review and meta-analysis
    Cho Naing, Maxine A. Whittaker
    Infectious Diseases of Poverty.2018;[Epub]     CrossRef
  • On the epidemiology of Plasmodium vivax malaria: past and present with special reference to the former USSR
    Anatoly V. Kondrashin, Lola F. Morozova, Ekaterina V. Stepanova, Natalia A. Turbabina, Maria S. Maksimova, Evgeny N. Morozov
    Malaria Journal.2018;[Epub]     CrossRef
  • Serum Lipids and Lipoproteins During Uncomplicated Malaria: A Cohort Study in Lambaréné, Gabon
    Petra F. Mens, Rik B. J. Kraan, Benjamin J. Visser, Sophia G. de Vries, Selidji T. Agnandji, Peter G. Kremsner, Rosanne W. Wieten, Danielle Kroon, François Danion, Lídia Ciudad Aguilar, Michèle van Vugt, Barbara Sjouke, Martin P. Grobusch, Akim A. Adegnik
    The American Journal of Tropical Medicine and Hygiene.2017; 96(5): 1205.     CrossRef
  • Utility of nested polymerase chain reaction over the microscopy and immuno-chromatographic test in the detection of Plasmodium species and their clinical spectrum
    P. Ranjan, U. Ghoshal
    Parasitology Research.2016; 115(9): 3375.     CrossRef
  • 11,721 View
  • 103 Download
  • 18 Web of Science
  • Crossref

Brief Communication

Genetic Polymorphisms in VIR Genes among Indian Plasmodium vivax Populations
Purva Gupta, Veena Pande, Aparup Das, Vineeta Singh
Korean J Parasitol 2014;52(5):557-564.
Published online October 22, 2014
DOI: https://doi.org/10.3347/kjp.2014.52.5.557

The vir genes are antigenic genes and are considered to be possible vaccine targets. Since India is highly endemic to Plasmodium vivax, we sequenced 5 different vir genes and investigated DNA sequence variations in 93 single-clonal P. vivax isolates. High variability was observed in all the 5 vir genes; the vir 1/9 gene was highly diverged across Indian populations. The patterns of genetic diversity do not follow geographical locations, as geographically distant populations were found to be genetically similar. The results in general present complex genetic diversity patterns in India, requiring further in-depth population genetic and functional studies.

Citations

Citations to this article as recorded by  Crossref logo
  • Genomic dynamics of clinical Plasmodium vivax: comparative genomic hybridization in severe malaria cases
    Sampreeti Tahbildar, Pon Arunachalam Boopathi, Sanjay Kumar Kochar, Dhanpat Kumar Kochar, Mohamed Aiyaz, Raja C. Mugasimangalam, Sudha N. Rao, Ashis Das
    Frontiers in Malaria.2025;[Epub]     CrossRef
  • Population genetic analysis of Plasmodium vivax vir genes in Pakistan
    Sylvatrie-Danne Dinzouna-Boutamba, Zin Moon, Sanghyun Lee, Sahib Gul Afridi, Hương Giang Lê, Yeonchul Hong, Byoung-Kuk Na, Youn-Kyoung Goo
    Parasites, Hosts and Diseases.2024; 62(3): 313.     CrossRef
  • Misidentification of Plasmodium Species by Cross-Reacting Primers and Cerebral Malaria Caused by Plasmodium vivax
    Anoopkrishna Rai, Deepak Sebastian Pinto, Praveen Rai, Srinivas Teerthanath, Indrani Karunasagar, Rama Adiga
    Journal of Health and Allied Sciences NU.2023; 13(04): 563.     CrossRef
  • Vivax Malaria and the Potential Role of the Subtelomeric Multigene vir Superfamily
    Youn-Kyoung Goo
    Microorganisms.2022; 10(6): 1083.     CrossRef
  • Humoral and cellular immune response to Plasmodium vivax VIR recombinant and synthetic antigens in individuals naturally exposed to P. vivax in the Republic of Korea
    Sanghyun Lee, Young-Ki Choi, Youn-Kyoung Goo
    Malaria Journal.2021;[Epub]     CrossRef
  • Diversity of vir Genes in Plasmodium vivax from Endemic Regions in the Republic of Korea: an Initial Evaluation
    Ui-han Son, Sylvatrie-Danne Dinzouna-Boutamba, Sanghyun Lee, Hae Soo Yun, Jung-Yeon Kim, So-Young Joo, Sookwan Jeong, Man Hee Rhee, Yeonchul Hong, Dong-Il Chung, Dongmi Kwak, Youn-Kyoung Goo
    The Korean Journal of Parasitology.2017; 55(2): 149.     CrossRef
  • Clinical manifestations and molecular mechanisms in the changing paradigm of vivax malaria in India
    Purva Gupta, Rajni Sharma, Jagdish Chandra, Virender Kumar, Ruchi Singh, Veena Pande, Vineeta Singh
    Infection, Genetics and Evolution.2016; 39: 317.     CrossRef
  • Acute kidney injury in malaria: An update
    Anand Chellappan, D.S. Bhadauria
    Clinical Queries: Nephrology.2016; 5(1): 26.     CrossRef
  • Plasmodium vivax msp-3α polymorphisms: analysis in the Indian subcontinent
    Anju Verma, Hema Joshi, Vineeta Singh, Anup Anvikar, Neena Valecha
    Malaria Journal.2016;[Epub]     CrossRef
  • Design, construction and validation of a Plasmodium vivax microarray for the transcriptome profiling of clinical isolates
    Pon Arunachalam Boopathi, Amit Kumar Subudhi, Sheetal Middha, Jyoti Acharya, Raja Chinnadurai Mugasimangalam, Sanjay Kumar Kochar, Dhanpat Kumar Kochar, Ashis Das
    Acta Tropica.2016; 164: 438.     CrossRef
  • 10,664 View
  • 102 Download
  • 9 Web of Science
  • Crossref

Original Article

IgG Avidity Antibodies against Toxoplasma gondii in High Risk Females of Reproductive Age Group in India
Naushaba Siddiqui, Fatima Shujatullah, Haris M. Khan, Tamkin Rabbani, Parvez A. Khan
Korean J Parasitol 2014;52(5):487-491.
Published online October 22, 2014
DOI: https://doi.org/10.3347/kjp.2014.52.5.487

Toxoplasma gondii is an obligate intracellular protozoan that is distributed worldwide. Recently, several tests for avidity of Toxoplasma IgG antibodies have been introduced to help discriminate between recently acquired and distant infections. The study was conducted in Jawaharlal Nehru Medical College and Hospital, India from February 2011 to September 2012. Serum specimens were subjected to Toxoplasma IgM ELISA and IgG avidity ELISA test. Out of 48 patients with abortions, 17 (35.4%) were positive for IgM ELISA, and 8 (16.6%) had low IgG avidity antibodies. Out of 48 patients with other obstetric problems, 23 (47.9%) were positive for IgM ELISA, and 17 (35.4%) had low IgG avidity antibodies. Combining both groups on avidity test, only 25 of 40 (62.5%) IgM-positive women had low-avidity IgG antibodies suggesting a recent T. gondii infection in these women. More importantly, 15 (37.5%) of the IgM-positive women had high-avidity antibodies suggesting that the infection was acquired before gestation The relation of IgM seropositivity with the following risk factors was not found to be statistically significant; contact with cats (0.13), non-vegetarian food habits (0.05), and low socio-economic status (0.49). While, for IgG avidity ELISA, only contact with cats (0.01) was significantly associated with seropositivity. All other risk factors have P-values of >0.05 (not significant). IgG avidity test when used in combination with IgM test was a valuable assay for diagnosis of ongoing or recently acquired T. gondii infection in India.

Citations

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  • A meta-analysis and survey on the prevalence of Toxoplasma gondii infection in cats (Felis catus)
    Mohd Ubaid, Umra Fatima Zuberi, Syed Muhammad Sarosh Ghalib, Faizeaab Hashmi, Sana Aqeel
    The Journal of Basic and Applied Zoology.2025;[Epub]     CrossRef
  • Seroprevalence and associated behavioral factors of Toxoplasma gondii infection among pregnant women in Pokhara Valley, Nepal
    Mamata Thapa, Tulsi Ram Gompo, Tatsuki Sugi, Masahito Asada, Hiroaki Arima, Kishor Pandey
    Tropical Medicine and Health.2025;[Epub]     CrossRef
  • Relationship between the serum level, polymorphism and gene expression of IL-33 in samples of recurrent miscarriage Iraqi women infected with toxoplasmosis
    Sabreen Hadi Fadhil, Entsar Jabbar Saheb
    Experimental Parasitology.2024; 263-264: 108799.     CrossRef
  • Detection of persistent low IgG avidity–an interpretative problem in the diagnosis of acute toxoplasmosis
    Petr Kodym, Zuzana Kurzová, Dagmar Berenová, Marek Malý, Gheyath K. Nasrallah
    PLOS ONE.2023; 18(4): e0284499.     CrossRef
  • Diagnosis of Acute Toxoplasmosis in the First Trimester of Pregnancy by IgG Avidity
    Afshin Azimi, Mahdi Parsaei, Eissa Soleymani, Elham Mehranzadeh, Amir Hossein Maghsood
    Avicenna Journal of Clinical Medicine.2022; 29(1): 50.     CrossRef
  • Toxoplasma gondii infection and spontaneous abortion: A systematic review and meta-analysis
    Narges Kalantari, Tahmineh Gorgani-Firouzjaee, Zahra Moulana, Mohammad Chehrazi, Salman Ghaffari
    Microbial Pathogenesis.2021; 158: 105070.     CrossRef
  • The global seroprevalence of anti-Toxoplasma gondii antibodies in women who had spontaneous abortion: A systematic review and meta-analysis
    Tooran Nayeri, Shahabeddin Sarvi, Mahmood Moosazadeh, Afsaneh Amouei, Zahra Hosseininejad, Ahmad Daryani, Maria Angeles Gómez-Morales
    PLOS Neglected Tropical Diseases.2020; 14(3): e0008103.     CrossRef
  • Analysis Concentration of <i>Toxoplasma gondii</i> on Anti-Toxoplasma IgG-IgM Antibody Levels, and the Outcomes of Pregnancy in Mice Balb/c
    Tigor Peniel Simanjuntak, Mochammad Hatta, Robert H. Sirait, Marni Br Karo, Lenny Irmawaty Sirait, Tetty Rina Aritonang, Syahrul Rauf, Ressy Dwiyanti
    Open Journal of Obstetrics and Gynecology.2017; 07(03): 281.     CrossRef
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    Naglaa F.A. Imam, Esra'a A.A. Azzam, Ahmed A. Attia
    Journal of Taibah University Medical Sciences.2016; 11(3): 255.     CrossRef
  • 9,252 View
  • 83 Download
  • 9 Web of Science
  • Crossref

Brief Communication

Whole Mitochondrial Genome Sequence of an Indian Plasmodium falciparum Field Isolate
Suchi Tyagi, Veena Pande, Aparup Das
Korean J Parasitol 2014;52(1):99-103.
Published online February 19, 2014
DOI: https://doi.org/10.3347/kjp.2014.52.1.99

Mitochondrial genome sequence of malaria parasites has served as a potential marker for inferring evolutionary history of the Plasmodium genus. In Plasmodium falciparum, the mitochondrial genome sequences from around the globe have provided important evolutionary understanding, but no Indian sequence has yet been utilized. We have sequenced the whole mitochondrial genome of a single P. falciparum field isolate from India using novel primers and compared with the 3D7 reference sequence and 1 previously reported Indian sequence. While the 2 Indian sequences were highly divergent from each other, the presently sequenced isolate was highly similar to the reference 3D7 strain.

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Case Reports
Cystic Echinococcosis of the Pelvic Bone with Recurrences: A Case Report
Sunila Jain, Prem Chopra
Korean J Parasitol 2011;49(3):277-279.
Published online September 30, 2011
DOI: https://doi.org/10.3347/kjp.2011.49.3.277

Hydatid cysts commonly affect the liver and the lung. However, they rarely involve bones with vertebral column. We hereby report a case of a female patient with cystic echinococcosis of the hip bone and ilium. She presented with a long history of frequent recurrences highlighting the dismal prognosis at this rare site. Resection of the hydatid cyst from the sacroiliac region was done with allograft and autograft (rib graft) with lumbosacroiliac fixation. Follow-up of the patient at 6 months showed no detectable abnormality on radiology and the patient was doing well.

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External Ophthalmomyiasis Caused by Oestrus ovis: A Rare Case Report from India
Anita Pandey, Molly Madan, Ashish K. Asthana, Anupam Das, Sandeep Kumar, Kirti Jain
Korean J Parasitol 2009;47(1):57-59.
Published online March 12, 2009
DOI: https://doi.org/10.3347/kjp.2009.47.1.57

Myiasis of different organs has been reported off and on from various regions in the world. We report a human case of external ophthalmomyiasis caused by the larvae of a sheep nasal botfly, Oestrus ovis, for the first time from Meerut city in Western Uttar Pradesh, India. A 25-year-old farmer presented with severe symptoms of conjunctivitis. The larvae, 3 in number, were observed in the bulbar conjunctiva, and following removal the symptoms of eye inflammation improved within a few hours.

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