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"Mun-Hyoo Jeong"

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"Mun-Hyoo Jeong"

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Failure of Repeated MDA with Albendazole for Trichuriasis Control in Schoolchildren of the Yangon Region, Myanmar
Sooji Hong, Bong-Kwang Jung, Hyemi Song, Jaeeun Cho, Woon-Mok Sohn, Sung-Jong Hong, Jin-Youp Ryu, Hyun-Seung Kim, Mun-Hyoo Jeong, Thi Thi Htoon, Htay Htay Tin, Jong-Yil Chai
Korean J Parasitol 2021;59(6):607-613.
Published online December 22, 2021
DOI: https://doi.org/10.3347/kjp.2021.59.6.607
Soil-transmitted helminth (STH) infections are still a considerable challenge in Myanmar. We undertook a control program for STH infections (especially Trichuris trichiura) among schoolchildren in Myanmar using mass drug administration (MDA) and health education. Around 1,700 schoolchildren from 15 primary schools in 3 suburban districts (Shwe Pyi Thar, Twantay, and Kyauktan) of the Yangon Region were subjected in this study during 2017-2019. All of the schoolchildren in each school were orally administered albendazole (400 mg in a single dose) 2, 3, and 4 times a year in 2017, 2018, and 2019, respectively. The results revealed that the egg positive rate of any intestinal helminths (including STH) was reduced from 37.6% (649/1,724) in 2017 to 22.8% (352/1,542) in 2019. The egg positive rate of Ascaris lumbricoides was decreased remarkably from 23.3% (402/1,724) in 2017 to 3.6% (56/1,542) in 2019. However, that of T. trichiura was only slightly reduced from 26.9% (464/1,724) in 2017 to 20.2% (312/1,542) in 2019. The intensity of infection with A. lumbricoides and T. trichiura was both more or less reduced, and the proportion of light infection cases with A. lumbricoides and T. trichiura increased from 35.6% in 2017 to 64.3% in 2019 and from 70.3% in 2017 to 81.7% in 2019, respectively. The results indicated that repeated MDAs (2-4 times a year for 3 years) using albendazole on schoolchildren in Myanmar failed to control T. trichiura infection. For a successful control of trichuriasis in Myanmar, new MDA strategies, using a modified albendazole regimen (multiple daily doses for 2 or 3 days) or an alternative anthelmintic drug, such as oxantel pamoate, is strongly recommended.

Citations

Citations to this article as recorded by  Crossref logo
  • Assessing soil-transmitted helminths and Schistosoma mansoni infections using parasitological indicators after seven years of preventive chemotherapy among school-age children in Mizan-Aman town
    Mitiku Abera, Tariku Belay, Daniel Emana, Zeleke Mekonnen, Uwem Friday Ekpo
    PLOS Neglected Tropical Diseases.2025; 19(5): e0013058.     CrossRef
  • Standard- and large-sized eggs of Trichuris trichiura in the feces of schoolchildren in the Yangon Region, Myanmar: Morphological and molecular analyses
    Seungwan Ryoo, Bong-Kwang Jung, Sooji Hong, Hyejoo Shin, Hyemi Song, Hyun-Seung Kim, Jin-Youp Ryu, Woon-Mok Sohn, Sung-Jong Hong, Thi Thi Htoon, Htay Htay Tin, Jong-Yil Chai
    Parasites, Hosts and Diseases.2023; 61(3): 317.     CrossRef
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Echinostoma miyagawai Ishii, 1932 (Echinostomatidae) from Ducks in Aceh Province, Indonesia with Special Reference to Its Synonymy with Echinostoma robustum Yamaguti, 1935
Jong-Yil Chai, Bong-Kwang Jung, Taehee Chang, Hyejoo Shin, Jaeeun Cho, Jin-Youp Ryu, Hyun-Seung Kim, Kwanghoon Park, Mun-Hyoo Jeong, Eui-Hyug Hoang, Marzuki Bin Muhammad Abdullah
Korean J Parasitol 2021;59(1):35-45.
Published online February 19, 2021
DOI: https://doi.org/10.3347/kjp.2021.59.1.35
Adult echinostomes having 37 collar spines collected from the intestine of Pitalah ducks in Aceh Province, Indonesia in 2018 were morphologically and molecularly determined to be Echinostoma miyagawai Ishii, 1932 (Digenea: Echinostomatidae). Among 20 ducks examined, 7 (35.0%) were found to be infected with this echinostome, and the number of flukes collected was 48 in total with average 6.9 (1-17) worms per duck. The adult flukes were 7.2 (6.1-8.5) mm in length and 1.2 (1.0-1.4) mm in width (pre-ovarian or testicular level) and characterized by having a head collar armed with 37 collar spines (dorsal spines arranged in 2 alternating rows), including 5 end group spines, and variable morphology of the testes, irregularly or deeply lobed (3-5 lobes) at times with horizontal extension. The eggs within the worm uterus were 93 (79-105) ?m long and 62 (56-70) ?m wide. These morphological features were consistent with both E. miyagawai and Echinostoma robustum, for which synonymy to each other has been raised. Sequencing of 2 mitochondrial genes, cox1 and nad1, revealed high homology with E. miyagawai (98.6-100% for cox1 and 99.0-99.8% for nad1) and also with E. robustum (99.3-99.8% for nad1) deposited in GenBank. We accepted the synonymy between the 2 species and diagnosed our flukes as E. miyagawai (syn. E. robustum) with redescription of its morphology. Further studies are required to determine the biological characteristics of E. miyagawai in Aceh Province, Indonesia, including the intermediate host and larval stage information.

Citations

Citations to this article as recorded by  Crossref logo
  • Development of a duplex loop-mediated isothermal amplification together with lateral flow dipstick assay for the detection and discrimination of parasitic infections in chickens between cestodes belonging to genus Raillietina and trematodes in family Echi
    Wasin Panich, Thanawan Tejangkura, Thapana Chontananarth
    Research in Veterinary Science.2025; 185: 105539.     CrossRef
  • The Nuclear Ribosomal Transcription Units of Two Echinostomes and Their Taxonomic Implications for the Family Echinostomatidae
    Yu Cao, Ye Li, Zhong-Yan Gao, Bo-Tao Jiang
    Biology.2025; 14(8): 1101.     CrossRef
  • Phylogeny and morphology of some Palearctic echinostomatid digeneans from rallid bird Fulica atra Linnaeus, 1758
    Sergei A. Vlasenkov, Mikhail Yu. Shchelkanov, Sergey G. Sokolov
    Biologia.2025; 80(11): 3079.     CrossRef
  • Catatropis indicus (Digenea: Notocotylidae) from ducks in Indonesia with a brief review of the genus Catatropis
    Jong-Yil Chai, Bong-Kwang Jung, Taehee Chang, Sooji Hong, Hyejoo Shin, Marzuki Bin Muhammad Abdullah
    Parasites, Hosts and Diseases.2025; 63(4): 303.     CrossRef
  • Development and utilization of a visual loop-mediated isothermal amplification coupled with a lateral flow dipstick (LAMP-LFD) assay for rapid detection of Echinostomatidae metacercaria in edible snail samples
    Wasin Panich, Phonkawin Jaruboonyakorn, Awika Raksaman, Thanawan Tejangkura, Thapana Chontananarth
    International Journal of Food Microbiology.2024; 418: 110732.     CrossRef
  • Molecular epidemiological analyses reveal extensive connectivity between Echinostoma revolutum (sensu stricto) populations across Eurasia and species richness of zoonotic echinostomatids in England
    Egie E. Enabulele, Scott P. Lawton, Anthony J. Walker, Ruth S. Kirk, Hudson Alves Pinto
    PLOS ONE.2023; 18(2): e0270672.     CrossRef
  • A new cryptic species of Echinostoma (Trematoda: Echinostomatidae) closely related to Echinostoma paraensei found in Brazil
    Marisa C. Valadão, Philippe V. Alves, Danimar López-Hernández, Jordana C. A. Assis, Paulo R. S. Coelho, Stefan M. Geiger, Hudson A. Pinto
    Parasitology.2023; 150(4): 337.     CrossRef
  • A new species ofEchinostoma(Trematoda: Echinostomatidae) from the ‘revolutum’ group found in Brazil: refuting the occurrence ofEchinostoma miyagawai(=E. robustum) in the Americas
    Marisa C. Valadão, Danimar López-Hernández, Philippe V. Alves, Hudson A. Pinto
    Parasitology.2022; 149(3): 325.     CrossRef
  • Echinostoma mekongi: Discovery of Its Metacercarial Stage in Snails, Filopaludina martensi cambodjensis, in Pursat Province, Cambodia
    Jong-Yil Chai, Woon-Mok Sohn, Jaeeun Cho, Bong-Kwang Jung, Taehee Chang, Keon Hoon Lee, Virak Khieu, Rekol Huy
    The Korean Journal of Parasitology.2021; 59(1): 47.     CrossRef
  • 5,828 View
  • 111 Download
  • 9 Web of Science
  • Crossref