Parasites, Hosts and Diseases

"co-infection"

Case Report

Two Imported Cases of Babesiosis with Complication or Co-Infection with Lyme Disease in Republic of Korea: Hea Yoon Kwon, Jae Hyoung Im, Yun-Kyu Park, Areum Durey, Jin-Soo Lee, Ji Hyeon Baek; Korean J Parasitol 2018;56(6):609-613.
Published online December 31, 2018; DOI: https://doi.org/10.3347/kjp.2018.56.6.609

Abstract
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Babesiosis, caused by Babesia microti and B. divergens, is transmitted by Ixodid ticks. Symptoms of babesiosis vary from a mild flu-like illness to acute, severe, and sometimes fatal and fulminant disease. In Korea, 7 imported babesiosis cases and 1 endemic case have been reported. We report 2 cases of severe babesiosis initially mistaken as malaria. The first patient was complicated by shock and splenic infarction, the other co-infected with Lyme disease. As the population traveling abroad increases every year, physicians should be aware of babesiosis which mimics malaria, co-infection with other diseases, and its complications.

Citations

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Imported parasitic diseases in the Republic of Korea: status and issues
Jong-Yil Chai
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Kaetlyn Arant, Ty Agaisse, Athanasios Vassilopoulos, Sassine Ghanem, Michael Santos
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Detection of US and Kobe‐type Babesia microti in ticks collected from small mammals of the Republic of Korea
Tae Yun Kim, Seong Yoon Kim, Jiye Seo, Hee IL Lee, Wook‐Gyo Lee, Hyunwoo Kim
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Current Status of Trypanosoma grosi and Babesia microti in Small Mammals in the Republic of Korea
Hyun Jung Kim, BoGyeong Han, Hee-Il Lee, Jung-Won Ju, Hyun-Il Shin
Animals.2024; 14(7): 989. CrossRef
Imported human babesiosis in the Republic of Korea, 2019: two case reports
Hyun Jung Kim, Min Jae Kim, Hyun-Il Shin, Jung-Won Ju, Hee-Il Lee
Parasites, Hosts and Diseases.2023; 61(1): 72. CrossRef
iSeq 100 for metagenomic pathogen screening in ticks
Ju Yeong Kim, Myung-hee Yi, Alghurabi Areej Sabri Mahdi, Tai-Soon Yong
Parasites & Vectors.2021;[Epub] CrossRef
Molecular evidence of zoonotic Babesia species, other than B. microti, in ixodid ticks collected from small mammals in the Republic of Korea
Tae Yun Kim, Seong Yoon Kim, Tae‐Kyu Kim, Hee IL Lee, Shin‐Hyeong Cho, Wook‐Gyo Lee, Hyunwoo Kim
Veterinary Medicine and Science.2021; 7(6): 2427. CrossRef
Interactions between Babesia microti merozoites and rat kidney cells in a short-term in vitro culture and animal model
Marta Albertyńska, Hubert Okła, Krzysztof Jasik, Danuta Urbańska-Jasik, Przemysław Pol
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A Review of Zoonotic Babesiosis as an Emerging Public Health Threat in Asia
Sabir Hussain, Abrar Hussain, Muhammad Umair Aziz, Baolin Song, Jehan Zeb, David George, Jun Li, Olivier Sparagano
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Splenic Complications ofBabesia microtiInfection in Humans: A Systematic Review
Igor Dumic, Cristian Madrid, Libardo Rueda Prada, Charles W. Nordstrom, Pahnwat Tonya Taweesedt, Poornima Ramanan
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A Practical Approach to the Diagnosis of Lyme Borreliosis: From Clinical Heterogeneity to Laboratory Methods
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Original Article

High Frequency of Enteric Protozoan, Viral, and Bacterial Potential Pathogens in Community-Acquired Acute Diarrheal Episodes: Evidence Based on Results of Luminex Gastrointestinal Pathogen Panel Assay: Yousry A. Hawash, Khadiga A. Ismail, Mazen Almehmadi; Korean J Parasitol 2017;55(5):513-521.
Published online October 31, 2017; DOI: https://doi.org/10.3347/kjp.2017.55.5.513

Abstract
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Infectious diarrhea is endemic in most developing countries. We aimed to investigate the protozoan, viral, and bacterial causes of acute diarrhea in Taif, Saudi Arabia. A cross-sectional prospective 1-year study was conducted on 163 diarrheal patients of various ages. Stool samples were collected, 1 per patient, and tested for 3 protozoa, 3 viruses, and 9 bacteria with the Luminex Gastrointestinal Pathogen Panel. Overall, 53.4% (87/163) of samples were positives (20.8% protozoa, 19.6% viruses, 2.8% bacteria, and 9.8% mixed). Rotavirus (19.6%), Giardia duodenalis (16.5%), and Cryptosporidium spp. (8.5%) were the mostly detected pathogens. Adenovirus 40/41 (4.2%), Salmonella (3%), Shiga toxin-producing Escherichia coli (3%), and Entamoeba histolytica (2.4%) were also detected. Norovirus GI/II, Vibrio cholerae, Yersinia enterocolitica, and Clostridium difficile toxin A/B were not detected in any patients. All pathogens were involved in coinfections except E. histolytica. Giardia (5.5%) and rotavirus (3%) were the most commonly detected in co-infections. Enterotoxigenic E. coli (2.4%), Campylobacter spp. (2.4%), E. coli 0157 (1.8%), and Shigella spp. (1.2%) were detected in patients only as co-infections. Infections were more in children 0-4 years, less in adults <40 years, and least >40 years, with statistically significant differences in risk across age groups observed with rotavirus (P<0.001), Giardia (P=0.006), and Cryptosporidium (P=0.036) infections. Lastly, infections were not significantly more in the spring. This report demonstrates the high burden of various enteropathogens in the setting. Further studies are needed to define the impact of these findings on the clinical course of the disease.

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Jae Jin Yang, Kunsong Lee
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Israa Elbashir, Noor F. Aldoos, Shilu Mathew, Asmaa A. Al Thani, Mohamed M. Emara, Hadi M. Yassine
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Denise Andrade Colito, Roberto Dorta-Guerra, Hailton Spencer Da Costa Lima, Carine Pina, Deisy Gonçalves, Basilio Valladares, Pilar Foronda
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Articles from Symposium on Asian Taenia (October 2011, Osong, Korea)

Current Status of Taeniasis in Thailand: Malinee Thairungroj Anantaphruti; Korean J Parasitol 2013;51(1):37-42.
Published online February 18, 2013; DOI: https://doi.org/10.3347/kjp.2013.51.1.37

Abstract
PDF

Taeniasis is prevalent in all regions of Thailand, except the South. Infections were more frequently found in males than females of any age from 7-83 years. Taenia saginata is the most common species throughout the country. Taenia asiatica was reported only in the province of Kanchanaburi in the Central region. Co-infections, with Taenia solium and T. asiatica or T. solium and T. saginata, were found. Hybridization between T. asiatica and T. saginata is evidence that co-infection is never found between these 2 species. Finding more than 1 worm in a single patient was not entirely rare. Genetic variation was found without correlation to its geographic distribution in T. saginata, whereas no variation was found in T. asiatica.

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Nationwide spatial dynamics of taeniasis in Thailand: declining prevalence but shifting focus and One Health risk factors across 2008–2014
Pornphutthachat Sota, Kefyalew Addis Alene, Thitima Wongsaroj, Sirikachorn Tangkawattana, Archie C. A. Clements, Banchob Sripa
Parasites & Vectors.2025;[Epub] CrossRef
Assessment of knowledge and practices regarding taeniasis and cysticercosis in Pak Chong, Nakhon Ratchasima, Thailand: A cross-sectional study
Wuttipong Phumrattanaprapin, Nitima Tatiya-apiradee, Pattana Jantaban, Wiriya Mahikul, Gideon Zulu
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Current prevalence and geographic distribution of helminth infections in the parasitic endemic areas of rural Northeastern Thailand
Pongsakorn Martviset, Wansika Phadungsil, Kesara Na-Bangchang, Wiwat Sungkhabut, Tanutchamon Panupornpong, Parisa Prathaphan, Nattaya Torungkitmangmi, Salisa Chaimon, Chompunoot Wangboon, Mantana Jamklang, Sirilak Chumkiew, Pichanee Watthanasiri, Amornrat
BMC Public Health.2023;[Epub] CrossRef
A retrospective study of Taenia spp. in Cuban patients: what does molecular analysis tell us?
Luis Enrique Jerez Puebla, Fidel A. Núñez Fernández, Jorge Fraga Nodarse, Raul Cordovi Prado, Iraís Atencio Millán, Iredys Cruz Rodríguez, Rigoberto Fimia Duarte, Marina del Carmen Sánchez Romero, Sahily de la Caridad Ortega Medina, Ubaldo del Risco, Liss
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Epidemiology of Taenia saginata taeniosis/cysticercosis: a systematic review of the distribution in East, Southeast and South Asia
Ramon M. Eichenberger, Lian F. Thomas, Sarah Gabriël, Branco Bobić, Brecht Devleesschauwer, Lucy J. Robertson, Anastasios Saratsis, Paul R. Torgerson, Uffe C. Braae, Veronique Dermauw, Pierre Dorny
Parasites & Vectors.2020;[Epub] CrossRef
Taeniasis and cysticercosis in Asia: A review with emphasis on molecular approaches and local lifestyles
Akira Ito, Tiaoying Li, Toni Wandra, Paron Dekumyoy, Tetsuya Yanagida, Munehiro Okamoto, Christine M Budke
Acta Tropica.2019; 198: 105075. CrossRef
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Maria Teresa Galán-Puchades, Màrius Vicent Fuentes
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Anita Ale, Bjorn Victor, Nicolas Praet, Sarah Gabriël, Niko Speybroeck, Pierre Dorny, Brecht Devleesschauwer
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Current Status of Taeniasis in Thailand
Malinee Thairungroj Anantaphruti
The Korean Journal of Parasitology.2013; 51(1): 37. CrossRef
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Malinee Thairungroj Anantaphruti, Urusa Thaenkham, Dorn Watthanakulpanich, Orawan Phuphisut, Wanna Maipanich, Tippayarat Yoonuan, Supaporn Nuamtanong, Somjit Pubampen, Surapol Sanguankiat
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83 Download
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Case Report

A Case of Probable Mixed-Infection with Clonorchis sinensis and Fasciola sp.: CT and Parasitological Findings: Tae Yun Kim, Yun-Sik Lee, Ji Hye Yun, Jeong Ju Kim, Won Hyung Choi, In Hwan Oh, Hyun Ouk Song, Jong Phil Chu; Korean J Parasitol 2010;48(2):157-160.
Published online June 17, 2010; DOI: https://doi.org/10.3347/kjp.2010.48.2.157

Abstract
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We report here a human case probably mixed-infected with Clonorchis sinensis and Fasciola sp. who was diagnosed by computed tomography (CT) scan, serological findings, and/or fecal examination. The patient was a 43-year-old Korean female and was admitted to Kyung Hee University Hospital with the complaints of fever and abdominal pain. On admission, marked eosinophilia was noted in her peripheral blood. CT scan showed specific lesions for clonorchiasis and fascioliasis in the liver, along with lesions suggestive of amebic abscess. Micro-ELISA revealed positive results for the 2 helminthic infections. Eggs of C. sinensis and trophozoites of Entamoeba histolytica were observed in the stool. Treatment with praziquantel followed by metronidazole and tinidazole reduced abnormalities in the liver and eosinophilia. This is the first case report of a possible co-infection with 2 kinds of liver flukes in the Republic of Korea.

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Ultrasound and contrast-enhanced ultrasound (CEUS) in infective liver lesions
Nitin Chaubal, Thomas Thomsen, Adnan Kabaalioglu, David Srivastava, Stephanie Simone Rösch, Christoph F. Dietrich
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S. MAS-COMA, M. D. BARGUES, M. A. VALERO
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