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Volume 48(2); June 2010

Original Articles

Detection of Plasmodium vivax by Nested PCR and Real-Time PCR
Genc, Ahmet , Eroglu, Fadime , Koltas, Ismail Soner
Korean J Parasitol 2010;48(2):99-103.
DOI: https://doi.org/10.3347/kjp.2010.48.2.99
Malaria is endemic in the Cukurova region while it is sporadic in other regions of Turkey. Therefore, the laboratory and clinical diagnosis of malaria is important for the treatment of malaria. In this study, 92 blood samples that were taken from the suspected malaria patients for routine diagnosis in a period of 10 years between 1999 and 2009 were analyzed. All of these blood samples were examined by microscopic examinations using Giemsa-stained thick blood films, nested PCR, and real-time PCR. The sensitivity-specificity and positive-negative predictive values for these diagnostic tests were then calculated. It was found that the positive predictive values of microscopic examination of thick blood films, nested PCR, and real-time PCR were 47.8%, 56.5%, and 60.9% for malaria, respectively. The real-time PCR was found to have a specificity of 75% and sensitivity of 100%, while specificity and sensitivity of nested PCR was found 81.2% and 97.7% according to the microscopic examination of thick blood films, respectively.

Citations

Citations to this article as recorded by  Crossref logo
  • Optimization of the real-time PCR platform method using high-resolution melting analysis and comparison with sequencing and phylogenetic analysis for developing optimal malaria diagnostic methods
    Omid Ahmadi, Yousef Sharifi, Michael Saeed, Amirali Reihani, Seyed Aliakbar Shamsian, Elham Moghaddas, Hadi Mirahmadi, Soudabeh Etemadi, Reza Fotouhi-Ardakani, Mehdi Zarean
    Scientific Reports.2025;[Epub]     CrossRef
  • Isolation and identification of mosquito-borne zoonotic diseases in slaughterhouse in Daejeon
    Youngju Kim, Gyurae Kim, Sunkyong Song, Youngshik Jung, Seojin Park, Sang-Joon Lee, Ho-Seong Cho, Yeonsu Oh
    Korean Journal of Veterinary Service.2023; 46(2): 115.     CrossRef
  • Non-Human Primate Malaria Infections: A Review on the Epidemiology in Malaysia
    Nor Diyana Dian, Mohd Amirul Fitri A. Rahim, Sherwin Chan, Zulkarnain Md Idris
    International Journal of Environmental Research and Public Health.2022; 19(13): 7888.     CrossRef
  • A Review on PCR and POC-PCR - A Boon in the Diagnosis of COVID-19
    Singaravelan Sindhuja, Sivaperuman Amuthalakshmi, Calambur Nagarajan Nalini
    Current Pharmaceutical Analysis.2022; 18(8): 745.     CrossRef
  • Considerations on PCR-based methods for malaria diagnosis in China malaria diagnosis reference laboratory network
    Jianhai Yin, Mei Li, He Yan, Shuisen Zhou
    BioScience Trends.2018; 12(5): 510.     CrossRef
  • Molecular malaria diagnostics: A systematic review and meta-analysis
    Johanna M. Roth, Daniël A. Korevaar, Mariska M. G. Leeflang, Pètra F. Mens
    Critical Reviews in Clinical Laboratory Sciences.2016; 53(2): 87.     CrossRef
  • Sparse serological evidence of Plasmodium vivax transmission in the Ouest and Sud-Est departments of Haiti
    Thomas A. Weppelmann, Michael E. von Fricken, Brandon Lam, Taina Telisma, Alexandre Existe, Jean F. Lemoine, Joseph Larkin, Bernard A. Okech
    Acta Tropica.2016; 162: 27.     CrossRef
  • Detection of Mixed-Species Infections of Plasmodium falciparum and Plasmodium vivax by Nested PCR and Rapid Diagnostic Tests in Southeastern Iran
    Hossein Keshavarz, Ahmad Raeisi, Aliehsan Heidari, Asghar Fazaeli, Reyhaneh Ehtesham
    The American Journal of Tropical Medicine and Hygiene.2015; 93(1): 181.     CrossRef
  • Increased detection of Plasmodium knowlesi in Sandakan division, Sabah as revealed by PlasmoNex™
    Xiang Ting Goh, Yvonne AL Lim, Indra Vythilingam, Ching Hoong Chew, Ping Chin Lee, Romano Ngui, Tian Chye Tan, Nan Jiun Yap, Veeranoot Nissapatorn, Kek Heng Chua
    Malaria Journal.2013;[Epub]     CrossRef
  • Plasmodium-Specific Molecular Assays Produce Uninterpretable Results and Non-Plasmodium spp. Sequences in Field-Collected Anopheles Vectors
    Genelle F. Harrison, Desmond H. Foley, Leopoldo M. Rueda, Vanessa R. Melanson, Richard C. Wilkerson, Lewis S. Long, Jason H. Richardson, Terry A. Klein, Heung-Chul Kim, Won-Ja Lee
    The American Journal of Tropical Medicine and Hygiene.2013; 89(6): 1117.     CrossRef
  • Correlates of HIV and malaria co-infection in Southern India
    Ajay R Bharti, Shanmugam Saravanan, Vidya Madhavan, Davey M Smith, Jabin Sharma, Pachamuthu Balakrishnan, Scott L Letendre, Nagalingeswaran Kumarasamy
    Malaria Journal.2012;[Epub]     CrossRef
  • Molecular diagnosis of infections and resistance in veterinary and human parasites
    Peter W. Hunt
    Veterinary Parasitology.2011; 180(1-2): 12.     CrossRef
  • Incidence of Malaria in the Interior Division of Sabah, Malaysian Borneo, Based on Nested PCR
    Wan Fen Joveen-Neoh, Ka Lung Chong, Clemente Michael Vui Ling Wong, Tiek Ying Lau
    Journal of Parasitology Research.2011; 2011: 1.     CrossRef
  • 9,936 View
  • 104 Download
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Biological and Genetic Characterization of Cryptosporidium spp. and Giardia duodenalis Isolates from Five Hydrographical Basins in Northern Portugal
Andr? Almeida, Maria Jo?o Moreira, S?nia Soares, Maria de Lurdes Delgado, Jo?o Figueiredo, Elisabete Silva Magalh?es, Ant?nio Castro, Alexandra Viana Da Costa, Jos? Manuel Correia da Costa
Korean J Parasitol 2010;48(2):105-111.
Published online June 17, 2010
DOI: https://doi.org/10.3347/kjp.2010.48.2.105

To understand the situation of water contamination with Cryptosporidium spp. and Giardia spp. in the northern region of Portugal, we have established a long-term program aimed at pinpointing the sources of surface water and environmental contamination, working with the water-supply industry. Here, we describe the results obtained with raw water samples collected in rivers of the 5 hydrographical basins. A total of 283 samples were analyzed using the Method 1623 EPA, USA. Genetic characterization was performed by PCR and sequencing of genes 18S rRNA of Cryptosporidium spp. and β-giardin of Giardia spp. Infectious stages of the protozoa were detected in 72.8% (206 of 283) of the water samples, with 15.2% (43 of 283) positive for Giardia duodenalis cysts, 9.5% (27 of 283) positive for Cryptosporidium spp. oocysts, and 48.1% (136 of 283) samples positive for both parasites. The most common zoonotic species found were G. duodenalis assemblages A-I, A-II, B, and E genotypes, and Cryptosporidium parvum, Cryptosporidium andersoni, Cryptosporidium hominis, and Cryptosporidium muris. These results suggest that cryptosporidiosis and giardiasis are important public health issues in northern Portugal. To the authors' knowledge, this is the first report evaluating the concentration of environmental stages of Cryptosporidium and Giardia in raw water samples in the northern region of Portugal.

Citations

Citations to this article as recorded by  Crossref logo
  • Molecular investigation of ready-to-eat salads for Giardia duodenalis and Cryptosporidium spp. in Portugal
    Clarissa Perez Faria, Adelaide Pereira, Daniela Almeida, Miguel Pinto, Ágata Lourenço, Maria do Céu Sousa
    Food and Waterborne Parasitology.2023; 30: e00190.     CrossRef
  • Detection of Cryptosporidium spp. and Giardia spp. in Environmental Water Samples: A Journey into the Past and New Perspectives
    Marie-Stéphanie Fradette, Alexander I. Culley, Steve J. Charette
    Microorganisms.2022; 10(6): 1175.     CrossRef
  • Protozoa as the “Underdogs” for Microbiological Quality Evaluation of Fresh Vegetables
    Cláudia S. Marques, Susana Sousa, António Castro, Vânia Ferreira, Paula Teixeira, José M. Correia da Costa
    Applied Sciences.2022; 12(14): 7145.     CrossRef
  • Recombinant Expression And Indirect ELISA For COWP And HSP70 Proteins From Cryptosporidium andersoni
    Hao Peng, Linsheng Tang, Cuilan Wu, Jun Li, Li Tao, Changting Li, Zhongwei Chen, Yongping Xie
    Acta Tropica.2021; 214: 105767.     CrossRef
  • Development and evaluation of an off-the-slide genotyping technique for identifyingGiardiacysts andCryptosporidiumoocysts directly from US EPA Method 1623 slides
    M.W. Ware, S.P. Keely, E.N. Villegas
    Journal of Applied Microbiology.2013; 115(1): 298.     CrossRef
  • Cryptosporidium parvum causes gastroenteritis epidemics in the Nablus region of Palestine
    Ayman S. Hussein
    Tropical Medicine & International Health.2011; 16(1): 12.     CrossRef
  • Occurrence, Source, and Human Infection Potential of Cryptosporidium and Giardia spp. in Source and Tap Water in Shanghai, China
    Yaoyu Feng, Xukun Zhao, Jiaxu Chen, Wei Jin, Xiaonong Zhou, Na Li, Lin Wang, Lihua Xiao
    Applied and Environmental Microbiology.2011; 77(11): 3609.     CrossRef
  • Detecção de oocistos de Cryptosporidium spp e cistos de Giardia spp em mananciais e águas de abastecimento público
    Regina Célia Arantes Stancari, Marlene Correia
    Revista do Instituto Adolfo Lutz.2010; 69(4): 453.     CrossRef
  • 10,423 View
  • 100 Download
  • Crossref
Infection Status of Hospitalized Diarrheal Patients with Gastrointestinal Protozoa, Bacteria, and Viruses in the Republic of Korea
Hyeng-Il Cheun, Shin-Hyeong Cho, Jin-Hee Lee, Yi-Young Lim, Ji-Hye Jeon, Jae-Ran Yu, Tong-Soo Kim, Won-Ja Lee, Seung-Hak Cho, Deog-Yong Lee, Mi-Seon Park, Hye-Sook Jeong, Doo-Sung Chen, Yeong-Mi Ji, Mi-Hwa Kwon
Korean J Parasitol 2010;48(2):113-120.
Published online June 17, 2010
DOI: https://doi.org/10.3347/kjp.2010.48.2.113

To understand protozoan, viral, and bacterial infections in diarrheal patients, we analyzed positivity and mixed-infection status with 3 protozoans, 4 viruses, and 10 bacteria in hospitalized diarrheal patients during 2004-2006 in the Republic of Korea. A total of 76,652 stool samples were collected from 96 hospitals across the nation. The positivity for protozoa, viruses, and bacteria was 129, 1,759, and 1,797 per 10,000 persons, respectively. Especially, Cryptosporidium parvum was highly mixed-infected with rotavirus among pediatric diarrheal patients (29.5 per 100 C. parvum positive cases), and Entamoeba histolytica was mixed-infected with Clostridium perfringens (10.3 per 100 E. histolytica positive cases) in protozoan-diarrheal patients. Those infected with rotavirus and C. perfringens constituted relatively high proportions among mixed infection cases from January to April. The positivity for rotavirus among viral infection for those aged ≤ 5 years was significantly higher, while C. perfringens among bacterial infection was higher for ≥ 50 years. The information for association of viral and bacterial infections with enteropathogenic protozoa in diarrheal patients may contribute to improvement of care for diarrhea as well as development of control strategies for diarrheal diseases in Korea.

Citations

Citations to this article as recorded by  Crossref logo
  • Molecular mechanisms of Shigella effector proteins: a common pathogen among diarrheic pediatric population
    Ahmad Nasser, Mehrdad Mosadegh, Taher Azimi, Aref Shariati
    Molecular and Cellular Pediatrics.2022;[Epub]     CrossRef
  • Prevalence of rotavirus among older children and adults with diarrhea: A systematic review and meta-analysis
    Lola Arakaki, Deanna Tollefson, Brenda Kharono, Paul K. Drain
    Vaccine.2021; 39(33): 4577.     CrossRef
  • Antioxidants, inhibits the growth of foodborne pathogens and reduces nitric oxide activity in LPS-stimulated RAW 264.7 cells of nipa palm vinegar
    Wilaiwan Senghoi, Wiyada Kwanhian Klangbud
    PeerJ.2021; 9: e12151.     CrossRef
  • Molecular Detection and Epidemiological Features of Selected Bacterial, Viral, and Parasitic Enteropathogens in Stool Specimens from Children with Acute Diarrhea in Thi-Qar Governorate, Iraq
    Ali Harb, Sam Abraham, Bertha Rusdi, Tanya Laird, Mark O’Dea, Ihab Habib
    International Journal of Environmental Research and Public Health.2019; 16(9): 1573.     CrossRef
  • Molecular Prevalence and Genotypes of Cryptosporidium parvum and Giardia duodenalis in Patients with Acute Diarrhea in Korea, 2013-2016
    Da-Won Ma, Myoung-Ro Lee, Sung-Hee Hong, Shin-Hyeong Cho, Sang-Eun Lee
    The Korean Journal of Parasitology.2019; 57(5): 531.     CrossRef
  • Monitoring of Noxious Protozoa for Management of Natural Water Resources
    Young Yil Bahk, Pyo Yun Cho, Sung Kyu Ahn, Sangjung Park, Won Hwa Jheong, Yun-Kyu Park, Ho-Joon Shin, Sang-Seob Lee, Okjae Rhee, Tong-Soo Kim
    The Korean Journal of Parasitology.2018; 56(2): 205.     CrossRef
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    Miguel Romero, R. Cerritos, Cecilia Ximenez
    Journal of Parasitology Research.2016; 2016: 1.     CrossRef
  • A Case of Colitis by <i>Giardia lamblia</i> Infection with Atypical Presentation
    Soo Kyoung Choi, Youn Hee Lee, Jinhee Lee, Seon Ho Park, Mi Hee Kim, Ok-Ran Shin, Young-Seok Cho
    The Korean Journal of Medicine.2015; 89(3): 312.     CrossRef
  • Fatal cryptosporidiosis in a calf
    Kang-Hyun Baek, Hyun-Kyoung Lee, Kyung-Hyun Lee, Ha-Young Kim, Jung-Won Park, Bo-Ram Lee, Ji-Woong Her, Myoung-Heon Lee, You-Chan Bae
    Korean Journal of Veterinary Research.2014; 54(4): 257.     CrossRef
  • The First Outbreak of Giardiasis with Drinking Water in Korea
    Hyeng-Il Cheun, Cheon-Hyeon Kim, Shin-Hyeong Cho, Da-Won Ma, Bo-La Goo, Mun-Su Na, Seung-Ki Youn, Won-Ja Lee
    Osong Public Health and Research Perspectives.2013; 4(2): 89.     CrossRef
  • Chemotherapeutic drugs for common parasitic diseases in Korea
    Sun Huh
    Journal of the Korean Medical Association.2013; 56(6): 513.     CrossRef
  • Prevalence and characters of Entamoeba histolytica infection in Saudi infants and children admitted with diarrhea at 2 main hospitals at south Jeddah: a re-emerging serious infection with unusual presentation
    Moustafa Abdelaal Hegazi, Tabarek Ahmed Patel, Basem Salama El-Deek
    The Brazilian Journal of Infectious Diseases.2013; 17(1): 32.     CrossRef
  • Health Risk Assessment of Cryptosporidium in Tap Water in Korea
    Mok-Young Lee, Sang-Jung Park, Eun-Joo Cho, Su-Jeong Park, Sun-Hee Han, Oh-Sang Kwon
    Korean Journal of Environmental Health Sciences.2013; 39(1): 32.     CrossRef
  • Enteric Protozoa in the Developed World: a Public Health Perspective
    Stephanie M. Fletcher, Damien Stark, John Harkness, John Ellis
    Clinical Microbiology Reviews.2012; 25(3): 420.     CrossRef
  • A Ten-year Survey ofGiardia Cystsin Drinking Water Supplies of Seoul, the Republic of Korea
    Mok-Young Lee, Eun-Joo Cho, Jin-Hyo Lee, Sun-Hee Han, Yong-Sang Park
    The Korean Journal of Parasitology.2011; 49(1): 9.     CrossRef
  • Trend in Viral Infectious Diseases in Children
    Sung Hee Oh
    Infection and Chemotherapy.2011; 43(6): 435.     CrossRef
  • Defining the causes of diarrhea
    Darwin J. Operario, Eric Houpt
    Current Opinion in Infectious Diseases.2011; 24(5): 464.     CrossRef
  • Burden of rotavirus and other enteropathogens among children with diarrhea in Burkina Faso
    Leon W. Nitiema, Johan Nordgren, Djeneba Ouermi, Dayeri Dianou, Alfred S. Traore, Lennart Svensson, Jacques Simpore
    International Journal of Infectious Diseases.2011; 15(9): e646.     CrossRef
  • 10,092 View
  • 95 Download
  • Crossref
Parents' Knowledge about Enterobiasis Might Be One of the Most Important Risk Factors for Enterobiasis in Children
Dong-Hee Kim, Hyun-Mi Son, Joo Young Kim, Min Kyoung Cho, Mee Kyung Park, Sin Ye Kang, Bo Young Kim, Hak Sun Yu
Korean J Parasitol 2010;48(2):121-126.
Published online June 17, 2010
DOI: https://doi.org/10.3347/kjp.2010.48.2.121

To know the prevalence of Enterobius vermicularis infection and what are the most important risk factors, we evaluated the incidence and risk factors of enterobiasis among children attended in kindergartens in Busan metropolitan city, Republic of Korea. A total of 1,674 children from 21 kindergartens in 11 of 16 autonomous districts of Busan were evaluated for E. vermicularis infection by the cellotape anal swab technique. The overall egg-positive rate for E. vermicularis was 10.7% (179/1,674), and the prevalence of enterobiasis in each kindergarten ranged between 0% and 32.4%. There was an increasing tendency of the egg positive rate according to the population density; the higher the population density communities had, the higher egg-positive rate for E. vermicularis was detected (P = 0.001). Among personal hygiene factors involving children, thumb-sucking (P = 0.036) and fingernail-trimming (P = 0.024) were highly associated with enterobiasis. In addition, taking anthelmintic medications against E. vermicularis infection was strongly associated with enterobiasis (P = 0.014). Moreover, parents' knowledge of enterobiasis was correlated significantly with the incidence of enterobiasis of their children (P = 0.006). In conclusion, we need to consider not only personal hygiene but also parents' knowledge about enterobiasis as a factor in order to develop new strategies for elimination or to complete reduction of enterobiasis in Korea.

Citations

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  • Unveiling the disparities between private and public preschools in the risk for pinworm infections in China: a multicentre cross-sectional study
    Fanzhen Mao, Xiangzhen Xu, Feng Tang, Bixian Ni, Qiang Zhang, Jiayao Zhang, Yaobao Liu, You Li, Jun Cao
    BMC Public Health.2025;[Epub]     CrossRef
  • Epidemiological and molecular characterization of Enterobius vermicularis cases in Mersin, Turkey: An analysis based on mitochondrial DNA cox1 gene sequences
    Harun Gülbudak, Seda Tezcan Ülger, Taylan Bozok, Gönül Aslan
    One Health.2025; 20: 101079.     CrossRef
  • Parasitoses intestinales infantiles
    P. Bourée
    EMC - Traité de médecine AKOS.2025; 28(3): 1.     CrossRef
  • Enterobius vermicularis infection and its risk factors among rural schoolchildren in Zhejiang Province: a cross-sectional study
    Jialie Jin, Wei Ruan, Wenjie Xu, Xuan Zhang, Kegen Yu, Hualiang Chen, Jiaqi Zhang, Jimin Sun, Jianmin Jiang, Xiaoxiao Wang
    Parasitology Research.2025;[Epub]     CrossRef
  • Pinworm (Enterobius Vermicularis) Infestation: An Updated Review
    Alexander K.C. Leung, Joseph M. Lam, Benjamin Barankin, Alex H.C. Wong, Kin F. Leong, Kam L. Hon
    Current Pediatric Reviews.2025; 21(4): 333.     CrossRef
  • Parasitosis intestinales en niños
    P. Bourée
    EMC - Tratado de Medicina.2025; 29(4): 1.     CrossRef
  • Parassitosi intestinali infantili
    P. Bourée
    EMC - AKOS - Trattato di Medicina.2025; 27(4): 1.     CrossRef
  • Oxyurose, trichocéphalose et ankylostomoses
    F. Robert-Gangneux, B. Autier, C. Guiguen
    EMC - Maladies infectieuses.2024; 41(3): 1.     CrossRef
  • Global prevalence of enterobiasis in young children over the past 20 years: a systematic review and meta-analysis
    Elham Kia Lashaki, Azadeh Mizani, Seyed Abdollah Hosseini, Bentolhoda Habibi, Khadijeh Taherkhani, Amir Javadi, AliReza Taremiha, Samira Dodangeh
    Osong Public Health and Research Perspectives.2023; 14(6): 441.     CrossRef
  • Enterobiasis among Yemeni children: a cross-sectional study
    Abdulelah H. Al-Adhroey, Yahya A. Al-Ansi, Mohammed A. Al-Kholani, Abdulrahman H. Amer, Marwan M. Al-Khyat, Fadia H. Al Hubaishi, Radhwan H. Aziz, Ebrahim S. Al-Khateeb, Souad A. Al-Gabri, Tawfik M. Al-Gabri
    Journal of Parasitic Diseases.2022; 46(3): 722.     CrossRef
  • Prevalence and genetic analysis of Enterobius vermicularis in schoolchildren in lower northern Thailand
    Pichamon Janthu, Abdulhakam Dumidae, Chanakan Subkrasae, Jiranun Ardpairin, Saengchai Nateeworanart, Aunchalee Thanwisai, Apichat Vitta
    Parasitology Research.2022; 121(10): 2955.     CrossRef
  • Is pinworm infection still a public health concern among children in resource-rich regions? Trends in pinworm infection prevalence and associated factors among children in Hualien County, Taiwan: a retrospective cross-sectional study
    Yu-Chao Hsiao, Jen-Hung Wang, Chia-Hsiang Chu, Yu-Hsun Chang, Yung-Chieh Chang, Rong-Hwa Jan, Shao-Yin Chu, Shang-Hsien Yang, Jui-Shia Chen, Ming-Chun Chen
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    Tropical Medicine and Health.2020;[Epub]     CrossRef
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    European Journal of Clinical Microbiology & Infectious Diseases.2019; 38(4): 719.     CrossRef
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    Journal of Microbiology, Immunology and Infection.2018; 51(4): 559.     CrossRef
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    Diagnostyka Laboratoryjna.2018; 54(1): 5.     CrossRef
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    Mahmood Moosazadeh, Ghasem Abedi, Mahdi Afshari, Seif Ali Mahdavi, Fereshteh Farshidi, Elham Kheradmand
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    T. S. Anuar, L. Jalilah, M. Norhayati, M. Y. Azlin, M. S. Fatmah, H. M. Al-Mekhlafi
    Helminthologia.2016; 53(1): 76.     CrossRef
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    Shuai Wang, Zhijun Yao, Yichen Hou, Dong Wang, Haizhu Zhang, Jingbo Ma, Luwen Zhang, Shiguo Liu
    Parasite.2016; 23: 30.     CrossRef
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    Hong-Mei Li, Chang-Hai Zhou, Zhi-Shi Li, Zhuo-Hui Deng, Cai-Wen Ruan, Qi-Ming Zhang, Ting-Jun Zhu, Long-Qi Xu, Ying-Dan Chen
    Infectious Diseases of Poverty.2015;[Epub]     CrossRef
  • Negligible Egg Positive Rate of <i>Enterobius vermicularis</i> and No Detection of Head Lice among Orphanage Children in Busan and Ulsan, Korea (2014)
    Dong-Hee Kim, Hyun-Mi Son, Sang Hwa Lee, Mi Kyung Park, Shin Ae Kang, Sang Kyun Park, Jun-Ho Choi, Jung Ha Park, Hak-Sun Yu
    The Korean Journal of Parasitology.2015; 53(4): 497.     CrossRef
  • Kindergarten Teacher’s Knowledge of Enterobiasis in Korea
    Dong-Hee Kim, Hak-Sun Yu
    Open Journal of Nursing.2014; 04(04): 330.     CrossRef
  • Effect of a One-Off Educational Session about Enterobiasis on Knowledge, Preventative Practices, and Infection Rates among Schoolchildren in South Korea
    Dong-Hee Kim, Hak Sun Yu, David Joseph Diemert
    PLoS ONE.2014; 9(11): e112149.     CrossRef
  • Environmental Factors Related to Enterobiasis in a Southeast Region of Korea
    Dong-Hee Kim, Min Kyoung Cho, Mi Kyung Park, Shin Ae Kang, Bo Young Kim, Sang Kyun Park, Hak Sun Yu
    The Korean Journal of Parasitology.2013; 51(1): 139.     CrossRef
  • Enterobius vermicularis and Risk Factors in Healthy Norwegian Children
    Håkon Bøås, German Tapia, John A. Sødahl, Trond Rasmussen, Kjersti S. Rønningen
    Pediatric Infectious Disease Journal.2012; 31(9): 927.     CrossRef
  • Prevalence of Enterobius vermicularis among Preschool Children in Muan-gun, Jeollanam-do, Korea
    Sung-Hee Hong, Young-Il Jeong, Jin-Hee Lee, Shin-Hyeong Cho, Won-Ja Lee, Sang-Eun Lee
    The Korean Journal of Parasitology.2012; 50(3): 259.     CrossRef
  • Impact of health education on the prevalence of enterobiasis in Korean preschool students
    In-Soon Kang, Dong-Hee Kim, Hye-Gyung An, Hyun-Mi Son, Min Kyoung Cho, Mi-Kyung Park, Shin Ae Kang, Bo Young Kim, Hak Sun Yu
    Acta Tropica.2012; 122(1): 59.     CrossRef
  • Prevalence ofEnterobius vermicularisamong Preschool Children in Gimhae-si, Gyeongsangnam-do, Korea
    Sang-Eun Lee, Jin-Hee Lee, Jung-Won Ju, Won-Ja Lee, Shin-Hyeong Cho
    The Korean Journal of Parasitology.2011; 49(2): 183.     CrossRef
  • Comparison of Egg Positive Rates ofEnterobius vermicularisamong Preschool Children in Three Korean Localities
    Sung-Hee Hong, Sang-Eun Lee, Young-Il Jeong, Won-Ja Lee, Shin-Hyeong Cho
    The Korean Journal of Parasitology.2011; 49(4): 441.     CrossRef
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Carboxylic Acids as Biomarkers of Biomphalaria alexandrina Snails Infected with Schistosoma mansoni
Salwa M. F. Abou Elseoud, Nashwa S. Abdel Fattah, Hayam M. Ezz El Din, Hala Abdel Al, Hanan Mossalem, Noha Elleboudy
Korean J Parasitol 2010;48(2):127-132.
Published online June 17, 2010
DOI: https://doi.org/10.3347/kjp.2010.48.2.127

Biomphalaria alexandrina snails play an indispensable role in transmission of schistosomiasis. Infection rates in field populations of snails are routinely determined by cercarial shedding neglecting prepatent snail infections, because of lack of a suitable method for diagnosis. The present study aimed at separation and quantification of oxalic, malic, acetic, pyruvic, and fumaric acids using ion-suppression reversed-phase high performance liquid chromatography (HPLC) to test the potentiality of these acids to be used as diagnostic and therapeutic biomarkers. The assay was done in both hemolymph and digestive gland-gonad complex (DGG) samples in a total of 300 B. alexandrina snails. All of the studied acids in both the hemolymph and tissue samples except for the fumaric acid in hemolymph appeared to be good diagnostic biomarkers as they provide not only a good discrimination between the infected snails from the control but also between the studied stages of infection from each other. The most sensitive discriminating acid was malic acid in hemolymph samples as it showed the highest F-ratio. Using the Z-score, malic acid was found to be a good potential therapeutic biomarker in the prepatency stage, oxalic acid and acetic acid in the stage of patency, and malic acid and acetic acid at 2 weeks after patency. Quantification of carboxylic acids, using HPLC strategy, was fast, easy, and accurate in prediction of infected and uninfected snails and possibly to detect the stage of infection. It seems also useful for detection of the most suitable acids to be used as drug targets.

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  • Novel insights into the glucose metabolic alterations of freshwater snails: a pathway to molluscicide innovation and snail control strategies
    Tao Zheng, Jia Hao Liu, Ting Yao Zhu, Bin Li, Jia Shan Li, Yun Yang Gu, Juan Nie, Tao Xiong, Fang Guo Lu
    Parasitology Research.2024;[Epub]     CrossRef
  • NMR-based metabolomic responses of freshwater gastropod Bellamya aeruginosa to MC-producing and non MC-producing Microcystis aeruginosa
    Wen Yang, Yangfang Ye, Kaihong Lu, Zhongming Zheng, Jinyong Zhu
    Journal of Oceanology and Limnology.2022; 40(1): 260.     CrossRef
  • UHPLC-MS-Based Metabolomics Analysis Reveals the Process of Schistosomiasis in Mice
    Yuzheng Huang, Qiong Wu, Liang Zhao, Chunrong Xiong, Yongliang Xu, Xin Dong, Yan Wen, Jun Cao
    Frontiers in Microbiology.2020;[Epub]     CrossRef
  • Unveiling the oxidative metabolism of Achatina fulica (Mollusca: Gastropoda) experimentally infected to Angiostrongylus cantonensis (Nematoda: Metastrongylidae)
    Vinícius Menezes Tunholi-Alves, Victor Menezes Tunholi, Juberlan Garcia, Esther Maria Mota, Rosane Nora Castro, Emerson Guedes Pontes, Jairo Pinheiro
    Parasitology Research.2018; 117(6): 1773.     CrossRef
  • Advances in the Diagnosis of Human Schistosomiasis
    Kosala G. A. D. Weerakoon, Geoffrey N. Gobert, Pengfei Cai, Donald P. McManus
    Clinical Microbiology Reviews.2015; 28(4): 939.     CrossRef
  • Potential Correlation between Carboxylic Acid Metabolites in Biomphalaria alexandrina Snails after Exposure to Schistosoma mansoni Infection
    Salwa M. F. Abou Elseoud, Nashwa S. Abdel Fattah, Hayam M. Ezz El Din, Hala Abdel Al, Hanan Mossalem, Noha Elleboudy
    The Korean Journal of Parasitology.2012; 50(2): 119.     CrossRef
  • 8,894 View
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Epidemiological Survey on the Infection of Intestinal Flukes in Residents of Muan-gun, Jeollanam-do, the Republic of Korea
Shin-Hyeong Cho, Pyo-Yun Cho, Dong-Min Lee, Tong-Soo Kim, In-Sang Kim, Eun-Jung Hwang, Byoung-Kuk Na, Woon-Mok Sohn
Korean J Parasitol 2010;48(2):133-138.
Published online June 17, 2010
DOI: https://doi.org/10.3347/kjp.2010.48.2.133

Infection status of intestinal flukes was investigated in residents of Muan-gun, Jeollanam-do, the Republic of Korea. Total 1,257 fecal samples of residents were examined by formalin-ether sedimentation technique and Kato-Katz thick smear method. Helminth eggs were detected from 95 (7.6%) residents, and eggs of heterophyid flukes and Clonorchis sinensis were found from 62 (4.9%) and 40 (3.2%) cases, respectively. The larger heterophyid eggs, somewhat dark-brown in color and 37.7 × 21.5 ?m in average size, and found in 32 (2.6%) out of 62 egg positive cases of heterophyid flukes. To confirm the adult flukes, we performed worm recovery from 12 cases after praziquantel treatment and purgation with MgSO4. A total of 1,281 adult flukes, assigned to 7 species, were recovered from 9 cooperative cases. Heterophyes nocens (total 981 specimens) was collected from 9 cases, Stictodora fuscata (80) from 7, Gymnophalloides seoi (75) from 5, Pygidiopsis summa (140) from 3, Stellantchasmus falcatus (3) from 2, and Stictodora lari and Acanthotrema felis (each 1 worm) from 1 case each. The intrauterine eggs of S. fuscata collected from the recovered worm were identical with the larger heterophyid eggs detected in the stool examination. By the present study, it was confirmed that A. felis is a new intestinal fluke infecting humans, and residents in Muan-gun, Jeollanam-do are infected with variable species of intestinal trematodes.

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  • Infection characteristics of Metagonimus species (Digenea: Heterophyidae) metacercariae in fish from major rivers of Korea
    Woon-Mok Sohn
    Parasites, Hosts and Diseases.2024; 62(1): 1.     CrossRef
  • Global distribution of zoonotic digenetic trematodes: a scoping review
    Yue Hu, Rong-Jian Zhan, Shi-Lin Lu, Yi-Yang Zhang, Min-Yu Zhou, Hui Huang, Ding-Ding Wang, Tao Zhang, Zi-Xin Huang, Yun-Fei Zhou, Zhi-Yue Lv
    Infectious Diseases of Poverty.2024;[Epub]     CrossRef
  • Global prevalence of 4 neglected foodborne trematodes targeted for control by WHO: A scoping review to highlight the gaps
    Rachel Tidman, Kaushi S. T. Kanankege, Mathieu Bangert, Bernadette Abela-Ridder, Paul R. Torgerson
    PLOS Neglected Tropical Diseases.2023; 17(3): e0011073.     CrossRef
  • Infections with Zoonotic Trematode Metacercariae in Yellowfin Goby, Acanthogobius flavimanus, from Coastal Areas of Republic of Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Jung-Won Ju, Soon-Won Lee, Won-Seok Seok
    The Korean Journal of Parasitology.2018; 56(3): 259.     CrossRef
  • Fishborne zoonotic heterophyid infections: An update
    Jong-Yil Chai, Bong-Kwang Jung
    Food and Waterborne Parasitology.2017; 8-9: 33.     CrossRef
  • The importance of wild fish in the epidemiology of Clonorchis sinensis in Vietnam
    Thanh Ngoc Bui, Thanh Thi Pham, Nguyen Thi Nguyen, Ha Van Nguyen, Darwin Murrell, Van Thi Phan
    Parasitology Research.2016; 115(9): 3401.     CrossRef
  • Pygidiopsis summa (Digenea: Heterophyidae): Status of Metacercarial Infection in Mullets from Coastal Areas in the Republic of Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Won-Ja Lee, Mi-Yeoun Park, Soon-Won Lee, Seung-Bong Choi, Beom-Nyung Huh, Won-Seok Seok
    The Korean Journal of Parasitology.2016; 54(4): 497.     CrossRef
  • Stellantchasmus falcatus (Digenea: Heterophyidae) in Cambodia: Discovery of Metacercariae in Mullets and Recovery of Adult Flukes in an Experimental Hamster
    Jong-Yil Chai, Woon-Mok Sohn, Byoung-Kuk Na, Hoo-Gn Jeoung, Muth Sinuon, Duong Socheat
    The Korean Journal of Parasitology.2016; 54(4): 537.     CrossRef
  • Comparative Risk of Liver and Intestinal Fluke Infection from Either Wild-Caught or Cultured Fish in Vietnam
    Thi Van Phan, Ngoc Thanh Bui, Van Ha Nguyen, Darwin Murrell
    Vector-Borne and Zoonotic Diseases.2016; 16(12): 790.     CrossRef
  • Four Human Cases of Acanthotrema felis (Digenea: Heterophyidae) Infection in Korea
    Jong-Yil Chai, Jae-Lip Kim, Min Seo
    The Korean Journal of Parasitology.2014; 52(3): 291.     CrossRef
  • Comparative Morphology of Minute Intestinal Fluke Eggs That Can Occur in Human Stools in the Republic of Korea
    Jin-Joo Lee, Bong-Kwang Jung, Hyemi Lim, Mi Youn Lee, Sung-Yil Choi, Eun-Hee Shin, Jong-Yil Chai
    The Korean Journal of Parasitology.2012; 50(3): 207.     CrossRef
  • Infection Status of Estuarine Fish and Oysters with Intestinal Fluke Metacercariae in Muan-gun, Jeollanam-do, Korea
    Shin-Hyeong Cho, In-Sang Kim, Eun-Jung Hwang, Tong-Soo Kim, Byoung-Kuk Na, Woon-Mok Sohn
    The Korean Journal of Parasitology.2012; 50(3): 215.     CrossRef
  • Discovery ofMaritrema obstipum(Digenea: Microphallidae) from Migratory Birds in Korea
    Ok-Sik Chung, Woon-Mok Sohn, Jong-Yil Chai, Min Seo, Hye-Jung Lee
    The Korean Journal of Parasitology.2011; 49(4): 457.     CrossRef
  • Prevalence ofMetagonimusMetacercariae in Sweetfish,Plecoglossus altivelis, from Eastern and Southern Coastal Areas in Korea
    Shin-Hyeong Cho, Tong-Soo Kim, Byoung-Kuk Na, Woon-Mok Sohn
    The Korean Journal of Parasitology.2011; 49(2): 161.     CrossRef
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Extraintestinal Migration of Centrorhynchus sp. (Acanthocephala: Centrorhynchidae) in Experimentally Infected Rats
Chang-Jin Choi, Hye-Jung Lee, Jai-Hyang Go, Yun-Kyu Park, Jong-Yil Chai, Min Seo
Korean J Parasitol 2010;48(2):139-143.
Published online June 17, 2010
DOI: https://doi.org/10.3347/kjp.2010.48.2.139

Reptiles were known to serve as paratenic hosts for Centrorhynchus (Acanthocephala: Centrorhynchidae) in Korea, but the infection course in experimental animals was not elucidated yet. In this study, the tiger keelback snakes (Rhabdophis tigrinus) were collected and digested with artificial pepsin solution, and the larvae of Centrorhynchus were recovered from them. Then, the collected larvae were orally infected to rats for developmental observations. In rats, all the larvae were observed outside the intestine on day 3 post-infection (PI), including the mesentery and abdominal muscles. As for the development in rats, the ovary of Centrorhynchus sp. was observed at day 15 PI, and the cement glands were 3 in number. Based on the morphological characteristics, including the arrangement of proboscis hooks, these larvae proved to be a species of Centrorhynchus, and more studies were needed for species identification.

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  • Morphological variety and mechanisms of formation of acanthocephalan cysts in intermediate host
    V.P. Nikishin, T.V. Davydenko, E.M. Skorobrekhova
    Journal of Helminthology.2025;[Epub]     CrossRef
  • Helminth Fauna of Anatolian Rock Lizard Anatololacerta anatolica (Werner, 1902) from Western Anatolia, Türkiye
    E. B. Hastürk, S. Birlik, Ç. Ilgaz, A. G. Korkmaz, K. Candan, E. Yıldırım Caynak, Y. Kumlutaş
    Biology Bulletin.2025;[Epub]     CrossRef
  • Pathological and incidental findings in anurans from Ceará, northeastern Brazil
    Roberta da Rocha Braga, Deborah Praciano de Castro, Daniel Cassiano Lima, Cícero Ricardo de Oliveira, Robson Waldemar Ávila
    Ciência Animal Brasileira.2024;[Epub]     CrossRef
  • Achados patológicos e incidentais em anuros do Ceará, nordeste brasileiro
    Roberta da Rocha Braga, Deborah Praciano de Castro, Daniel Cassiano Lima, Cícero Ricardo de Oliveira, Robson Waldemar Ávila
    Ciência Animal Brasileira.2024;[Epub]     CrossRef
  • First report of acanthocephalan parasite in wild-caught Asian vine snake (Ahaetulla prasina) in Indonesia
    Aditya Yudhana, Ratih Novita Praja, Ryanka Edila
    Veterinary World.2023; : 317.     CrossRef
  • Identification of antiparasitic drug targets using a multi-omics workflow in the acanthocephalan model
    Hanno Schmidt, Katharina Mauer, Manuel Glaser, Bahram Sayyaf Dezfuli, Sören Lukas Hellmann, Ana Lúcia Silva Gomes, Falk Butter, Rebecca C. Wade, Thomas Hankeln, Holger Herlyn
    BMC Genomics.2022;[Epub]     CrossRef
  • Histopathology of lesions caused byPseudocorynosoma constrictum(Acanthocephala: Polymorphidae) in the ileum of blue-winged teal
    C. Caballero-Viñas, P. Sánchez-Nava
    Journal of Helminthology.2020;[Epub]     CrossRef
  • The genome, transcriptome, and proteome of the fish parasite Pomphorhynchus laevis (Acanthocephala)
    Katharina Mauer, Sören Lukas Hellmann, Marco Groth, Andreas C. Fröbius, Hans Zischler, Thomas Hankeln, Holger Herlyn, Zhong-Hua Chen
    PLOS ONE.2020; 15(6): e0232973.     CrossRef
  • Evolutionary anatomy of the muscular apparatus involved in the anchoring of Acanthocephala to the intestinal wall of their vertebrate hosts
    Holger Herlyn, Horst Taraschewski
    Parasitology Research.2017; 116(4): 1207.     CrossRef
  • Organization and evolution of the proboscis musculature in avian parasites of the genus Apororhynchus (Acanthocephala: Apororhynchida)
    Holger Herlyn
    Parasitology Research.2017; 116(7): 1801.     CrossRef
  • The helminth fauna of Apathya cappadocica (Werner, 1902) (Anatolian Lizard) (Squamata: Lacertidae) from Turkey
    S. Birlik, H. S. Yildirimhan, N. Sümer, Ç. Ilgaz, Kumlutaş, Ö. Güçlü, S. H. Durmuş
    Helminthologia.2015; 52(4): 310.     CrossRef
  • 13,765 View
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Survey of Flea Infestation in Dogs in Different Geographical Regions of Iran
Mosa Tavassoli, Amir Ahmadi, Abbas Imani, Emad Ahmadiara, Shahram Javadi, Mojtaba Hadian
Korean J Parasitol 2010;48(2):145-149.
Published online June 17, 2010
DOI: https://doi.org/10.3347/kjp.2010.48.2.145

Medically important arthropods, including fleas, play an important role in causing clinical disorders and disease in man and domestic animals. This study was conducted to determine the seasonal flea infestations for domestic dogs from different geographic regions of Iran. A total of 407 fleas, belonging to 5 different species, were recovered from 83 domestic dogs from 3 regions. There was a distinctive pattern of species distribution and infestations with the highest infestation rates observed in a temperate climate and higher rainfall. Additionally, fleas were observed over all seasons, except February and March, with the highest infestation rate observed in August (24.7%) and the lowest rate in January (1.7%). They also parasitize dogs with a different spectrum of species. The cat flea, Ctenocephalides felis (67.5%), exhibited the highest prevalence among all flea species found on dogs. Thus, climatic conditions and seasonal patterns impact on flea infestation and must be considered in developing control programs.

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    Zuhair Dardona, Samia Boussaa
    Public Health Challenges.2025;[Epub]     CrossRef
  • Molecular Identification, Multigenic Characterization and Phylogenetic Analysis of Ctenocephalides Canis Fleas from Humans and Domestic Animals in Iran
    Shahin Seidi, Mousa Tavassoli, Farnaz Malekifard, Mourad Ben Said
    Acta Parasitologica.2024; 69(2): 1219.     CrossRef
  • Detection of Bartonella spp. and Rickettsia spp. in cat fleas (Ctenocephalides felis) collected from free-roaming domestic cats in southeastern Georgia, USA
    Lisa D. Brown, Ryne Maness, Kania Greer
    Veterinary Parasitology: Regional Studies and Reports.2022; 32: 100743.     CrossRef
  • Türkiye’nin Muğla ili Datça ilçesinde sahipli köpeklerde pire enfestasyonları
    Mehmet ACIÖZ, Mehmet Fatih AYDIN
    Etlik Veteriner Mikrobiyoloji Dergisi.2020; 31(1): 70.     CrossRef
  • Fleas infesting cats and dogs in Great Britain: spatial distribution of infestation risk and its relation to treatment
    A‐R. Cooper, E. Nixon, H. Rose Vineer, S. Abdullah, H. Newbury, R. Wall
    Medical and Veterinary Entomology.2020; 34(4): 452.     CrossRef
  • Ectoparasites Ctenocephalides (Siphonaptera, Pulicidae) in the Composition of Mixed Infestations in Domestic Dogs from Poltava, Ukraine
    V. Yevstafieva, K. Horb, V. Melnychuk, T. Bakhur, D. Feshchenko
    Folia Veterinaria.2020; 64(3): 47.     CrossRef
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    Bersissa Kumsa, Yonas Abiy, Fufa Abunna
    Veterinary Parasitology: Regional Studies and Reports.2019; 15: 100263.     CrossRef
  • Molecular detection and identification of Wolbachia endosymbiont in fleas (Insecta: Siphonaptera)
    Zuhal Onder, Arif Ciloglu, Onder Duzlu, Alparslan Yildirim, Mubeccel Okur, Gamze Yetismis, Abdullah Inci
    Folia Microbiologica.2019; 64(6): 789.     CrossRef
  • Molecular survey of ITS1 spacer and Rickettsia infection in human flea, Pulex irritans
    Mohammad Bagher Ghavami, Habibeh Mirzadeh, Jamshid Mohammadi, Asghar Fazaeli
    Parasitology Research.2018; 117(5): 1433.     CrossRef
  • Evidence for the presence of Ctenocephalides orientis in livestock dwellings in northwest Iran
    S. J. Seyyed‐Zadeh, F. Bozorg‐Omid, Z. Telmadarraiy, O. Terenius, A. R. Chavshin
    Medical and Veterinary Entomology.2018; 32(3): 383.     CrossRef
  • Prevalence and Potential Risk Factors forBartonellaInfection in Tunisian Stray Dogs
    Jaber Belkhiria, Bruno B. Chomel, Taoufik Ben Hamida, Rickie W. Kasten, Matthew J. Stuckey, Drew A. Fleischman, Mary M. Christopher, Henri-Jean Boulouis, Thomas B. Farver
    Vector-Borne and Zoonotic Diseases.2017; 17(6): 388.     CrossRef
  • First molecular detection and characterization of zoonotic Bartonella species in fleas infesting domestic animals in Tunisia
    Saba Zouari, Fatma Khrouf, Youmna M’ghirbi, Ali Bouattour
    Parasites & Vectors.2017;[Epub]     CrossRef
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    Vicente Homero González-Álvarez, Isabel G. Fernández de Mera, Alejandro Cabezas-Cruz, José de la Fuente, Aldo I. Ortega-Morales, Consuelo Almazán
    Veterinary Parasitology: Regional Studies and Reports.2017; 10: 143.     CrossRef
  • Molecular detection of zoonotic bartonellae (B. henselae, B. elizabethae and B. rochalimae) in fleas collected from dogs in Israel
    S. SOFER, R. GUTIÉRREZ, D. MORICK, K. Y. MUMCUOGLU, S. HARRUS
    Medical and Veterinary Entomology.2015; 29(3): 344.     CrossRef
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    BMC Veterinary Research.2015;[Epub]     CrossRef
  • Molecular Detection of Rickettsia felis and Bartonella henselae in Dog and Cat Fleas in Central Oromia, Ethiopia
    Philippe Parola, Didier Raoult, Bersissa Kumsa, Cristina Socolovschi
    The American Journal of Tropical Medicine and Hygiene.2014; 90(3): 457.     CrossRef
  • A survey of ectoparasite infestation in dogs in Tehran, Iran
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    Revista Brasileira de Parasitologia Veterinária.2012; 21(3): 326.     CrossRef
  • Fleas as parasites of the family Canidae
    Gerhard Dobler, Martin Pfeffer
    Parasites & Vectors.2011;[Epub]     CrossRef
  • 10,967 View
  • 116 Download
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Enzymatic Activities of Allergen Extracts from Three Species of Dust Mites and Cockroaches Commonly Found in Korean Home
Kyoung Yong Jeong, Chungryul Kim, Tai-Soon Yong
Korean J Parasitol 2010;48(2):151-155.
Published online June 17, 2010
DOI: https://doi.org/10.3347/kjp.2010.48.2.151

Allergen extracts from dust mites and cockroaches commonly found in Korean homes were used to evaluate their enzymatic activity as they are believed to influence allergenicity. Allergen extracts were prepared from 3 dust mite species (Dermatophagoides farinae, D. pteronyssinus, and Tyrophagus putrescentiae) and 3 cockroach species (Blattella germanica, Periplaneta americana, and P. fuliginosa) maintained in the Korea National Arthropods of Medical Importance Resource Bank. Proteins were extracted in PBS after homogenization using liquid nitrogen. The activities of various enzymes were investigated using the API Zym system. No significant difference in phosphatase, lipase, or glycosidase activity was observed among the 6 allergen extracts, but much difference was observed in protease activity. Protease activity was assessed in more detail by gelatin zymography and the EnzChek assay. Extract from T. putrescentiae showed the highest protease activity, followed by those of the cockroach extracts. Extracts from D. farinae and D. pteronyssinus showed only weak protease activity. Gelatinolytic activity was detected mainly in a 30-kDa protein in D. farinae, a 28-kDa protein in D. pteronyssinus, a > 26-kDa protein in T. putrescentiae, a > 20-kDa protein in B. germanica, and a > 23-kDa protein in P. americana and P. fuliginosa. The information on various enzymatic activities obtained in this study may be useful for future studies. In particular, the strong protease activity found in cockroach extracts could contribute to sensitization to cockroach allergens, which is known to be associated with the development of asthma.

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  • B-cell antibody class switchings are pressuromodulated events: Part II, gene recombination
    Hemant Sarin
    Translational Medicine Communications.2018;[Epub]     CrossRef
  • Allergenic Characterization of a Novel Allergen, Homologous to Chymotrypsin, from German Cockroach
    Kyoung Yong Jeong, Mina Son, Jae-Hyun Lee, Chein-Soo Hong, Jung-Won Park
    Allergy, Asthma & Immunology Research.2015; 7(3): 283.     CrossRef
  • Current Status of Standardization of Inhalant Allergen Extracts in Korea
    Kyoung Yong Jeong, Jae-Hyun Lee, Eun-Jin Kim, Joo-Shil Lee, Sang-Heon Cho, Soo-Jong Hong, Jung-Won Park
    Allergy, Asthma & Immunology Research.2014; 6(3): 196.     CrossRef
  • Preparation and Characterization of an Extract of German Cockroach From a Korean Source
    Kyoung Yong Jeong, Soo-Young Choi, Jae-Hyun Lee, Joo-Shil Lee, Tai-Soon Yong, Chein-Soo Hong, Jung-Won Park
    Allergy, Asthma & Immunology Research.2013; 5(2): 102.     CrossRef
  • The Effects of Storage Conditions on the Stability of House Dust Mite Extracts
    Kyoung Yong Jeong, Soo-Young Choi, In-Soo Han, Jae-Hyun Lee, Joo-Shil Lee, Chein-Soo Hong, Jung-Won Park
    Allergy, Asthma & Immunology Research.2013; 5(6): 397.     CrossRef
  • House Dust Mite Allergy in Korea: The Most Important Inhalant Allergen in Current and Future
    Kyoung Yong Jeong, Jung-Won Park, Chein-Soo Hong
    Allergy, Asthma & Immunology Research.2012; 4(6): 313.     CrossRef
  • Role of Cockroach Proteases in Allergic Disease
    Kristen Page
    Current Allergy and Asthma Reports.2012; 12(5): 448.     CrossRef
  • Optimization of Allergen Standardization
    Kyoung Yong Jeong, Chein-Soo Hong, Joo-Shil Lee, Jung-Won Park
    Yonsei Medical Journal.2011; 52(3): 393.     CrossRef
  • 9,140 View
  • 82 Download
  • Crossref

Case Reports

A Case of Probable Mixed-Infection with Clonorchis sinensis and Fasciola sp.: CT and Parasitological Findings
Tae Yun Kim, Yun-Sik Lee, Ji Hye Yun, Jeong Ju Kim, Won Hyung Choi, In Hwan Oh, Hyun Ouk Song, Jong Phil Chu
Korean J Parasitol 2010;48(2):157-160.
Published online June 17, 2010
DOI: https://doi.org/10.3347/kjp.2010.48.2.157

We report here a human case probably mixed-infected with Clonorchis sinensis and Fasciola sp. who was diagnosed by computed tomography (CT) scan, serological findings, and/or fecal examination. The patient was a 43-year-old Korean female and was admitted to Kyung Hee University Hospital with the complaints of fever and abdominal pain. On admission, marked eosinophilia was noted in her peripheral blood. CT scan showed specific lesions for clonorchiasis and fascioliasis in the liver, along with lesions suggestive of amebic abscess. Micro-ELISA revealed positive results for the 2 helminthic infections. Eggs of C. sinensis and trophozoites of Entamoeba histolytica were observed in the stool. Treatment with praziquantel followed by metronidazole and tinidazole reduced abnormalities in the liver and eosinophilia. This is the first case report of a possible co-infection with 2 kinds of liver flukes in the Republic of Korea.

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  • Helminth/Protozoan Coinfections in Chronic Fascioliasis Cases in Human Hyperendemic Areas: High Risk of Multiparasitism Linked to Transmission Aspects and Immunological, Environmental and Social Factors
    M. Adela Valero, M. Manuela Morales-Suarez-Varela, Davis J. Marquez-Guzman, Rene Angles, Jose R. Espinoza, Pedro Ortiz, Filippo Curtale, M. Dolores Bargues, Santiago Mas-Coma
    Tropical Medicine and Infectious Disease.2025; 10(8): 224.     CrossRef
  • Fascioliasis: Image Findings, Diagnosis, and Treatment
    Jae Seung Lee
    Clinical Ultrasound.2024; 9(1): 18.     CrossRef
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An Imported Case of Echinococcosis of the Liver in a Korean Who Traveled to Western and Central Europe
Sun-Ju Byun, Kyung Chul Moon, Kyung-Suk Suh, Joon Koo Han, Jong-Yil Chai
Korean J Parasitol 2010;48(2):161-165.
Published online June 17, 2010
DOI: https://doi.org/10.3347/kjp.2010.48.2.161

Echinococcus granulosus, an intestinal tapeworm of dogs and other canids, infects humans in its larval stage and causes human echinococcosis or hydatid disease. In the Republic of Korea, 31 parasite-proven human echinococcosis cases have been reported, most of which were imported from the Middle East. We recently examined a 61-year-old Korean man who had a large cystic mass in his liver. ELISA was negative for tissue parasitic infections, including echinococcosis, cysticercosis, paragonimiasis, and sparganosis. The patient underwent surgery to remove the cyst, and the resected cyst was processed histopathologically for microscopic examinations. In sectioned cyst tissue, necrotizing protoscolices with disintegrated hooklets of E. granulosus were found. In some areas, only freed, fragmented hooklets were detected. The patient had traveled to western and central Europe in 1996, and had no other history of overseas travel. We report our patient as a hepatic echinococcosis case which was probably imported from Europe.

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A Human Case of Hymenolepis diminuta in a Child from Eastern Sicily
Ildebrando Patamia, Elisa Cappello, Donato Castellano-Chiodo, Filippo Greco, Luciano Nigro, Bruno Cacopardo
Korean J Parasitol 2010;48(2):167-169.
Published online June 17, 2010
DOI: https://doi.org/10.3347/kjp.2010.48.2.167

We report a case of Hymenolepis diminuta infection in a 2-year-old child living in a suburban area of Catania, Italy. This case was initially referred to us as Dipylidium caninum infection, which was not cured after being treated twice with mebendazole. However, by analyzing the clinical presentation and stool samples we arrived to the diagnosis of H. diminuta infection. The case presented with atypical allergic manifestations which had never been reported as clinical features of symptomatic H. diminuta infection; remittent fever with abdominal pain, diffuse cutaneous itching, transient thoracic rash, and arthromyalgias. The patient was treated with a 7-day cycle of oral niclosamide, which proved to be safe and effective. This case report emphasizes that a correct parasitological diagnosis requires adequate district laboratories and trained personnel. In addition, we recommend the importance of reporting all H. diminuta infection cases, in order to improve knowledge on epidemiology, clinical presentation, and treatment protocols.

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Brief Communications

Suppressed CD31 Expression in Sarcoma-180 Tumors after Injection with Toxoplasma gondii Lysate Antigen in BALB/c Mice
Kyoung-Ho Pyo, Bong-Kwang Jung, Jong-Yil Chai, Eun-Hee Shin
Korean J Parasitol 2010;48(2):171-174.
Published online June 17, 2010
DOI: https://doi.org/10.3347/kjp.2010.48.2.171

The anti-tumorigenic effects of Toxoplasma gondii (RH) antigens were studied in a murine sarcoma-180 tumor model. To determine the anti-tumor effects, the reduction in tumor size and expression of CD31 (an angiogenesis marker in the tumor tissue) were examined after injection of BALB/c mice with T. gondii lysate antigen (TLA) or formalin-fixed, proliferation-inhibited, T. gondii tachyzoites. Tumors were successfully produced by an intradermal injection of sarcoma-180 cells with plain Matrigel in the mid-backs of mice. After injection with TLA or formalin-fixed T. gondii tachyzoites, the increase in tumor size and weight nearly stopped while tumor growth continued in control mice that were injected with PBS. CD31 expression in TLA-treated or formalin-fixed T. gondii-injected mice was lower than the control mice. Accordingly, the present study shows that the treatment of mice with formalin-fixed T. gondii or TLA in the murine sarcoma-180 tumor model results in a decrease of both tumor size and CD31 expression.

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    Joung-Ho Moon, Kyoung-Ho Pyo, Bong-Kwang Jung, Hyang Sook Chun, Jong-Yil Chai, Eun-Hee Shin
    The Korean Journal of Parasitology.2011; 49(3): 303.     CrossRef
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Primaquine Administration after Falciparum Malaria Treatment in Malaria Hypoendemic Areas with High Incidence of Falciparum and Vivax Mixed Infection: Pros and Cons
Polrat Wilairatana, Noppadon Tangpukdee, Shigeyuki Kano, Srivicha Krudsood
Korean J Parasitol 2010;48(2):175-177.
Published online June 17, 2010
DOI: https://doi.org/10.3347/kjp.2010.48.2.175

Mixed infections of Plasmodium falciparum and Plasmodium vivax is high (~30%) in some malaria hypoendemic areas where the patients present with P. falciparum malaria diagnosed by microscopy. Conventional treatment of P. falciparum with concurrent chloroquine and 14 days of primaquine for all falciparum malaria patients may be useful in areas where mixed falciparum and vivax infections are high and common and also with mild or moderate G6PD deficiency in the population even with or without subpatent vivax mixed infection. It will be possibly cost-effective to reduce subsequent vivax illness if the patients have mixed vivax infection. Further study to prove this hypothesis may be warranted.

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  • Impact of enhanced malaria control on the competition between Plasmodium falciparum and Plasmodium vivax in India
    Olivia Prosper, Maia Martcheva
    Mathematical Biosciences.2013; 242(1): 33.     CrossRef
  • Elimination Therapy for the Endemic Malarias
    J. Kevin Baird
    Current Infectious Disease Reports.2012; 14(3): 227.     CrossRef
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Appropriate Time for Primaquine Treatment to Reduce Plasmodium falciparum Transmission in Hypoendemic Areas
Polrat Wilairatana, Srivicha Krudsood, Noppadon Tangpukdee
Korean J Parasitol 2010;48(2):179-182.
Published online June 17, 2010
DOI: https://doi.org/10.3347/kjp.2010.48.2.179

Artemesinin-combination therapies (ACT) for falciparum malaria reduce gametocyte carriage, and therefore reduce transmission. Artemisinin derivatives will act against only young gametocytes whereas primaquine acts on mature gametocytes which are present usually in the circulation at the time when the patient presents for treatment. Both artemisinin derivatives and primaquine have short half-lives, less than 1 hr and 7 hr, respectively. Therefore, asexual parasites or young gametocytes remain after completed ACT. A single dose of primaquine (0.50-0.75 mg base/kg) at the end of ACT can kill only mature gametocytes but cannot kill young gametocytes (if present). Remaining asexual forms after completion of ACT course, e.g., artesunate-mefloquine for 3 days, may develop to mature gametocytes 7-15 days later. Thus, an additional dose of primaquine (0.50-0.75 mg base/kg) given 2 weeks after ACT completion may be beneficial for killing remaining mature gametocytes and contribute to more interruption of Plasmodium falciparum transmission than giving only 1 single dose of primaquine just after completing ACT.

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    Michael J Delves
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    Eliana M. Arango, Yulieth A. Upegui, Jaime Carmona-Fonseca
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In a previous study, the author developed a method for separation of the tegument of spargana (plerocercoids of Spirometra mansoni) from the parenchyme using urea. The present study, as a next step, was performed to evaluate which molecules are present in the outer tegument. Two major proteins, 180 and 200 kDa, are present in the tegument and we could make polyclonal antibodies against these molecules. Their immunolocalization was processed and the outermost layer of the spargana showed strong positive staining. Conclusively, we could confirm that the 180 and 200 kDa molecules might be tightly bound membrane proteins in the tegument of spargana.

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  • Identification of an enolase gene and its physiological role in Spirometra mansoni
    Pei Liang, Xiuji Cui, Ruijia Fu, Peng Liang, Gang Lu, Dayong Wang
    Parasitology Research.2021; 120(6): 2095.     CrossRef
  • 7,286 View
  • 87 Download
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Book Review
Acanthamoeba: Biology and Pathogenesis
Hyun-Hee Kong
Korean J Parasitol 2010;48(2):187-187.
Published online June 17, 2010
DOI: https://doi.org/10.3347/kjp.2010.48.2.187
  • 5,788 View
  • 100 Download