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"Jae-Hwan Park"

Brief Communication

Intestinal Nematodes from Small Mammals Captured near the Demilitarized Zone, Gyeonggi Province, Republic of Korea
Deok-Gyu Kim, Jae-Hwan Park, Jae-Lip Kim, Bong-Kwang Jung, Sarah Jiyoun Jeon, Hyemi Lim, Mi Youn Lee, Eun-Hee Shin, Terry A. Klein, Heung-Chul Kim, Sung-Tae Chong, Jin-Won Song, Luck-Ju Baek, Jong-Yil Chai
Korean J Parasitol 2015;53(1):135-139.
Published online February 27, 2015
DOI: https://doi.org/10.3347/kjp.2015.53.1.135

A total of 1,708 small mammals (1,617 rodents and 91 soricomorphs), including Apodemus agrarius (n = 1,400), Microtus fortis (167), Crocidura lasiura (91), Mus musculus (32), Myodes (= Eothenomys) regulus (9), Micromys minutus (6), and Tscherskia (= Cricetulus) triton (3), were live-trapped at US/Republic of Korea (ROK) military training sites near the demilitarized zone (DMZ) of Paju, Pocheon, and Yeoncheon, Gyeonggi Province from December 2004 to December 2009. Small mammals were examined for their intestinal nematodes by necropsy. A total of 1,617 rodents (100%) and 91 (100%) soricomorphs were infected with at least 1 nematode species, including Nippostrongylus brasiliensis, Heligmosomoides polygyrus, Syphacia obvelata, Heterakis spumosa, Protospirura muris, Capillaria spp., Trichuris muris, Rictularia affinis, and an unidentified species. N. brasiliensis was the most common species infecting small mammals (1,060; 62.1%) followed by H. polygyrus (617; 36.1%), S. obvelata (370; 21.7%), H. spumosa (314; 18.4%), P. muris (123; 7.2%), and Capillaria spp. (59; 3.5%). Low infection rates (0.1-0.8%) were observed for T. muris, R. affinis, and an unidentified species. The number of recovered worms was highest for N. brasiliensis (21,623 worms; mean 20.4 worms/infected specimen) followed by S. obvelata (9,235; 25.0 worms), H. polygyrus (4,122; 6.7 worms), and H. spumosa (1,160; 3.7 worms). A. agrarius demonstrated the highest prevalence for N. brasiliensis (70.9%), followed by M. minutus (50.0%), T. triton (33.3%), M. fortis (28.1%), M. musculus (15.6%), C. lasiura (13.2%), and M. regulus (0%). This is the first report of nematode infections in small mammals captured near the DMZ in ROK.

Citations

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  • Intestinal parasites in rodents from five different Himas in Lebanon
    M. Abi Said, T. Maroun, H. Shaib
    Helminthologia.2025; 62(2): 120.     CrossRef
  • Helminthofauna Diversity in Synanthropic Rodents of the Emilia-Romagna Region (Italy): Implications for Public Health and Rodent Control
    Filippo Maria Dini, Carlotta Mazzoni Tondi, Roberta Galuppi
    Veterinary Sciences.2024; 11(11): 585.     CrossRef
  • The Parasites that can be Found in the Mus musculus House Mice
    Dilara KARAMAN, Ahmet Onur GİRİŞGİN
    Commagene Journal of Biology.2022;[Epub]     CrossRef
  • A newly identified secreted larval antigen elicits basophil-dependent protective immunity against N. brasiliensis infection
    Natalie Thuma, Daniela Döhler, Dirk Mielenz, Heinrich Sticht, Daniel Radtke, Lena Reimann, Bettina Warscheid, David Voehringer
    Frontiers in Immunology.2022;[Epub]     CrossRef
  • IL‐4/IL‐13‐producing ILC2s are required for timely control of intestinal helminth infection in mice
    Filipa Varela, Cornelia Symowski, Jonathan Pollock, Stefan Wirtz, David Voehringer
    European Journal of Immunology.2022; 52(12): 1925.     CrossRef
  • Rictularia jiyeoni n. sp. (Nematoda: Rictulariidae) from the Striped Field Mouse, Apodemus agrarius, in Korea
    Bae Keun Park, Hyeon Cheol Kim, Eui Ju Hong, Si Yun Ryu, Joon Seok Chae
    Journal of Parasitology.2021;[Epub]     CrossRef
  • A helminth-derived suppressor of ST2 blocks allergic responses
    Francesco Vacca, Caroline Chauché, Abhishek Jamwal, Elizabeth C Hinchy, Graham Heieis, Holly Webster, Adefunke Ogunkanbi, Zala Sekne, William F Gregory, Martin Wear, Georgia Perona-Wright, Matthew K Higgins, Josquin A Nys, E Suzanne Cohen, Henry J McSorle
    eLife.2020;[Epub]     CrossRef
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    Marie Wiedemann, David Voehringer
    Frontiers in Immunology.2020;[Epub]     CrossRef
  • Selective expression of constitutively activated STAT6 in intestinal epithelial cells promotes differentiation of secretory cells and protection against helminths
    Christoph Schubart, Branislav Krljanac, Manuel Otte, Cornelia Symowski, Eva Martini, Claudia Günther, Christoph Becker, Christoph Daniel, David Voehringer
    Mucosal Immunology.2019; 12(2): 413.     CrossRef
  • A novel controlled release microsponges containing Albendazole against Haemonchus contortus in experimentally infected goats
    Ahmed A.H. Abdellatif, Gamal M. Zayed, H.H. Kamel, Ahmed G. Mohamed, Waleed M. Arafa, Abdelrhman M. Khatib, Ossama M. Sayed
    Journal of Drug Delivery Science and Technology.2018; 43: 469.     CrossRef
  • Infections of Intestinal Helminth at Two Species of Field Mice, Apodemus agrarius and A. Peninsulae, in Gangwondo and Chungcheongnam-do, Korea
    Jae-Hyung Lee, Shuang Gong, Yung Chul Park, Hyun-Ju Kim, In-Wook Choi, Young-Ha Lee
    The Korean Journal of Parasitology.2018; 56(3): 301.     CrossRef
  • The Distribution and Habitat Characteristic of Tscherskia triton (Rodentia; Cricetidae) in Jeju Island, Korea
    Jun-Ho Park, Kang Il Kim, Man-Ho Kim, Hong-Shik Oh
    Environmental Biology Research.2018; 36(3): 412.     CrossRef
  • Seroprevalence of Toxoplasmosis with ELISA and Rapid Diagnostic Test among Residents in Gyodong-do, Inchon city, Korea: A Four-Year Follow-up
    Yeong Hoon Kim, Ji hoo Lee, Seong kyu Ahn, Tong-Soo Kim, Sung-Jong Hong, Chom-Kyu Chong, Hye-Jin Ahn, Ho-Woo Nam
    The Korean Journal of Parasitology.2017; 55(3): 247.     CrossRef
  • Seroprevalence of Toxoplasmosis Detected by RDT in Residents near the DMZ (demilitarized zone) of Cheorwon-gun, Gangwon-do, Korea
    Yeong Hoon Kim, Jihoo Lee, Young-Eun Kim, Seongkyu Ahn, Tong-Soo Kim, Sung-Jong Hong, Chom-Kyu Chong, Hye-Jin Ahn, Ho-Woo Nam
    The Korean Journal of Parasitology.2017; 55(4): 385.     CrossRef
  • 22,226 View
  • 235 Download
  • 15 Web of Science
  • Crossref

Original Articles

Increased Intestinal Epithelial Cell Turnover and Intestinal Motility in Gymnophalloides seoi-Infected C57BL/6 Mice
Sang Hyub Lee, Bong-Kwang Jung, Jae-Hwan Park, Eun-Hee Shin, Jong-Yil Chai
Korean J Parasitol 2014;52(3):273-280.
Published online June 26, 2014
DOI: https://doi.org/10.3347/kjp.2014.52.3.273

The changing patterns of goblet cell hyperplasia, intestinal epithelial cell turnover, and intestinal motility were studied in ICR and C57BL/6 mice infected with Gymnophalloides seoi (Digenea: Gymnophallidae). Whereas ICR mice retained G. seoi worms until day 7 post-infection (PI), C57BL/6 mice showed a rapid worm expulsion within day 3 PI. Immunosuppression with Depo-Medrol significantly delayed the worm expulsion in C57BL/6 mice. Goblet cell counts were increased in both strains of mice, peaking at day 1 PI in C57BL/6 mice and slowly increasing until day 7 PI in ICR mice. In C57BL/6 mice infected with G. seoi, newly proliferating intestinal epithelial cells were remarkably increased in the crypt, and the increase was the highest at day 1 PI. However, in ICR mice, newly proliferating intestinal epithelial cells increased slowly from day 1 to day 7 PI. Intestinal motility was increased in G. seoi-infected mice, and its chronological pattern was highly correlated with the worm load in both strains of mice. Meanwhile, immunosuppression of C57BL/6 mice abrogated the goblet cell proliferation, reduced the epithelial cell proliferation, and suppressed the intestinal motility. Goblet cell hyperplasia, increased intestinal epithelial cell turnover, and increased intestinal motility should be important mucosal defense mechanisms in G. seoi-infected C57BL/6 mice.

Citations

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  • Differential alterations in the small intestine epithelial cell turnover during acute and chronic infection with Echinostoma caproni (Trematoda)
    Alba Cortés, Carla Muñoz-Antoli, Carla Martín-Grau, J. Guillermo Esteban, Richard K. Grencis, Rafael Toledo
    Parasites & Vectors.2015;[Epub]     CrossRef
  • 10,509 View
  • 72 Download
  • 4 Web of Science
  • Crossref
Mucosal Immune Responses of Mice Experimentally Infected with Pygidiopsis summa (Trematoda: Heterophyidae)
Jong-Yil Chai, Young-Jin Park, Jae-Hwan Park, Bong-Kwang Jung, Eun-Hee Shin
Korean J Parasitol 2014;52(1):27-33.
Published online February 19, 2014
DOI: https://doi.org/10.3347/kjp.2014.52.1.27

Mucosal immune responses against Pygidiopsis summa (Trematoda: Heterophyidae) infection were studied in ICR mice. Experimental groups consisted of group 1 (uninfected controls), group 2 (infection with 200 metacercariae), and group 3 (immunosuppression with Depo-Medrol and infection with 200 metacercariae). Worms were recovered in the small intestine at days 1, 3, 5, and 7 post-infection (PI). Intestinal intraepithelial lymphocytes (IEL), mast cells, and goblet cells were counted in intestinal tissue sections stained with Giemsa, astra-blue, and periodic acid-Schiff, respectively. Mucosal IgA levels were measured by ELISA. Expulsion of P. summa from the mouse intestine began to occur from days 3-5 PI which sustained until day 7 PI. The worm expulsion was positively correlated with proliferation of IEL, mast cells, goblet cells, and increase of IgA, although in the case of mast cells significant increase was seen only at day 7 PI. Immunosuppression suppressed all these immune effectors and inhibited worm reduction in the intestine until day 7 PI. The results suggested that various immune effectors which include IEL, goblet cells, mast cells, and IgA play roles in regulating the intestinal mucosal immunity of ICR mice against P. summa infection.

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  • Anthelmintic potential of sulphonamides and Cucurbita pepo seeds extract on Heterophyes heterophyes experimentally infected mice
    Dalia S. Ashour, Fetouh A. Deyab, Kamal F. Eliwa, Samy I. El-Kowrany
    Journal of Parasitic Diseases.2023; 47(4): 697.     CrossRef
  • Intestinal polyparasitism and levels of mucosal anthelmintic SIgA in children from endemic areas in Northeastern Brazil
    Luciana M. Oliveira, Yvanna L. D. C. Oliveira, Yrna L. M. Oliveira, Anne Caroline S. Ramos, Gabriela F. Andrade, Vitor L. Sá, Ricardo M. Geraldi, Carina S. Pinheiro, Lilian L. Bueno, Ricardo T. Fujiwara, Silvio S. Dolabella
    Parasite Immunology.2022;[Epub]     CrossRef
  • The role of IgA in gastrointestinal helminthiasis: A systematic review
    Anne C.S. Ramos, Luciana M. Oliveira, Yvanna L.D.C.O. Santos, Marlon C.S. Dantas, Cristiani I.B. Walker, Ana M.C. Faria, Lílian L. Bueno, Silvio S. Dolabella, Ricardo T. Fujiwara
    Immunology Letters.2022; 249: 12.     CrossRef
  • Haplorchis pumilio (Trematoda: Heterophyidae) as a new fish-borne zoonotic agent transmitted by Melanoides tuberculata (Mollusca: Thiaridae) in Brazil: A morphological and molecular study
    André S. Lopes, Eduardo A. Pulido-Murillo, Alan L. Melo, Hudson A. Pinto
    Infection, Genetics and Evolution.2020; 85: 104495.     CrossRef
  • Fishborne zoonotic heterophyid infections: An update
    Jong-Yil Chai, Bong-Kwang Jung
    Food and Waterborne Parasitology.2017; 8-9: 33.     CrossRef
  • Pygidiopsis cambodiensis n. sp. (Digenea: Heterophyidae) from experimental hamsters infected with metacercariae in mullets from Cambodia
    Woon-Mok Sohn, Deok-Gyu Kim, Bong-Kwang Jung, Jaeeun Cho, Jong-Yil Chai
    Parasitology Research.2016; 115(1): 123.     CrossRef
  • Experimental centrocestiasis: Worm burden, morphology and fecundity of Centrocestus formosanus (Trematoda: Heterophyidae) in dexamethasone immunosuppressed mice
    Hudson Alves Pinto, Vitor Luís Tenório Mati, Alan Lane de Melo
    Parasitology International.2015; 64(5): 236.     CrossRef
  • 10,328 View
  • 103 Download
  • 6 Web of Science
  • Crossref

Brief Communications

Echinostome Infections in the Striped-Field Mouse, Apodemus agrarius, and the Ussuri White-Toothed Shrew, Crocidura lasiura, Caught Near the Demilitarized Zone, Gyeonggi-do (Province), Republic of Korea
Jong-Yil Chai, Jae-Hwan Park, Bong-Kwang Jung, Sang-Mee Guk, Jae-Lip Kim, Eun-Hee Shin, Terry A. Klein, Heung-Chul Kim, Sung-Tae Chong, Luck Ju Baek, Jin-Won Song
Korean J Parasitol 2009;47(3):311-314.
Published online August 28, 2009
DOI: https://doi.org/10.3347/kjp.2009.47.3.311

A total of 1,498 small mammals (rodents and insectivores), including Apodemus agrarius (n = 1,366), Crocidura lasiura (54), Mus musculus (32), Micronytus fortis (28), Eothenomys regulus (9), Micronys minutes (6), and Cricetulus triton (3), were live-trapped in Gyeonggi-do (Province) (Paju-si, Pocheon-gun, and Yeoncheon-gun) near the demilitarized zone (DMZ) from December 2004 to September 2005. A. agrarius was found to be infected with 3 species of echinostomes (Echinostoma hortense, Echinostoma cinetorchis, and Euparyphium murinum), while C. lasiura was infected with 1 species (Echinochasmus japonicas) of echinostome. Other mammals were free from echinostome infections. Total 16 E. hortense were detected in 7 (0.5%) mice, 9 E. cinetorchis from 5 (0.4%), and 3 E. murinum from 2 (0.1%) out of 1.366 A. agrarius examined. E. japonicus was found only in 1 (1.9%; total 3 specimens) C. lasiura. These results demonstrate that A. agrarius and C. lasiura, inhabiting near the DMZ of Gyeonggi-do serve as the natural definitive hosts for several species of echinostomes, although their infection rates are low. This is the first record of natural infections of A. agrarius with E. cinetorchis and C. lasiura with E. japonicus in the Republic of Korea.

Citations

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  • Global distribution of zoonotic digenetic trematodes: a scoping review
    Yue Hu, Rong-Jian Zhan, Shi-Lin Lu, Yi-Yang Zhang, Min-Yu Zhou, Hui Huang, Ding-Ding Wang, Tao Zhang, Zi-Xin Huang, Yun-Fei Zhou, Zhi-Yue Lv
    Infectious Diseases of Poverty.2024;[Epub]     CrossRef
  • Infections of Intestinal Helminth at Two Species of Field Mice, Apodemus agrarius and A. Peninsulae, in Gangwondo and Chungcheongnam-do, Korea
    Jae-Hyung Lee, Shuang Gong, Yung Chul Park, Hyun-Ju Kim, In-Wook Choi, Young-Ha Lee
    The Korean Journal of Parasitology.2018; 56(3): 301.     CrossRef
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    The Korean Journal of Parasitology.2016; 54(2): 173.     CrossRef
  • Helicobacter apodemussp. nov., a newHelicobacterspecies identified from the gastrointestinal tract of striped field mice in Korea
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    The Korean Journal of Parasitology.2014; 52(4): 419.     CrossRef
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  • Trematodes Recovered in the Small Intestine of Stray Cats in the Republic of Korea
    Jong-Yil Chai, Young Yil Bahk, Woon-Mok Sohn
    The Korean Journal of Parasitology.2013; 51(1): 99.     CrossRef
  • Fish-borne Parasitic Diseases
    Jong-Yil Chai
    Hanyang Medical Reviews.2010; 30(3): 223.     CrossRef
  • Foodborne Intestinal Flukes in Southeast Asia
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    The Korean Journal of Parasitology.2009; 47(Suppl): S69.     CrossRef
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  • 96 Download
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Intestinal Helminth Infections in Feral Cats and a Raccoon Dog on Aphaedo Island, Shinan-gun, with a Special Note on Gymnophalloides seoi Infection in Cats
Eun-Hee Shin, Jae-Hwan Park, Sang-Mee Guk, Jae-Lip Kim, Jong-Yil Chai
Korean J Parasitol 2009;47(2):189-191.
Published online May 26, 2009
DOI: https://doi.org/10.3347/kjp.2009.47.2.189

Four feral cats and a raccoon dog purchased from a local collector on Aphaedo Island, Shinan-gun, where human Gymnophalloides seoi infections are known to be prevalent, were examined for their intestinal helminth parasites. From 2 of 4 cats, a total of 310 adult G. seoi specimens were recovered. Other helminths detected in cats included Heterophyes nocens (1,527 specimens), Pygidiopsis summa (131), Stictodora fuscata (4), Acanthotrema felis (2), Spirometra erinacei (15), toxocarids (4), and a hookworm (1). A raccoon dog was found to be infected with a species of echinostome (55), hookworms (7), toxocarids (3), P. summa (3), and S. erinacei (1). No G. seoi was found in the raccoon dog. The results indicate that feral cats and raccoon dogs on Aphaedo are natural definitive hosts for intestinal trematodes and cestodes, including G. seoi, H. nocens, and S. erinacei. It has been first confirmed that cats, a mammalian species other than humans, play the role of a natural definitive host for G. seoi on Aphaedo Island.

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    Hyeon Cheol Kim, Eui Ju Hong, Si Yun Ryu, Jinho Park, Jeong Gon Cho, Do Hyeon Yu, Joon Seok Chae, Kyoung Seong Choi, Bae Keun Park
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  • 8,255 View
  • 101 Download
  • Crossref
Apodemus agrarius as a new definitive host for Neodiplostomum seoulense
Jong-Yil Chai, Jae-Hwan Park, Sang-Mee Guk, Jae-Lip Kim, Hyo-Jin Kim, Won-Hee Kim, Eun-Hee Shin, Terry A. Klein, Heung-Chul Kim, Sung-Tae Chong, Jin-Won Song, Luck-Ju Baek
Korean J Parasitol 2007;45(2):157-161.
Published online June 20, 2007
DOI: https://doi.org/10.3347/kjp.2007.45.2.157

A total of 1,496 rodents and insectivores were live-trapped at Yeoncheon-gun (n = 351), Paju-shi (804), and Pocheon-gun (343), Gyeonggi-do (Province), and examined for intestinal helminths, including Neodiplostomum seoulense, seasonally from December 2004 to September 2005. Six species of rodents, including Apodemus agrarius (1,366), Mus musculus (32), Micronytus fortis (28), Eothenomys regulus (9), Micronys minutus (6), and Cricetulus triton (3), and 1 species of insectivores Crocidura lasiura (54) were collected. A total of 321 adult N. seoulense were collected from 19 (1.4%) A. agrarius. The worm burden ranged from 1 to 101 per A. agrarius (mean; 16.9). No N. seoulense was observed in other rodent or insectivore species examined. The infection rate during autumn (4.5%) was higher than those during spring (0.8%), summer (0.8%), and winter (0.5%). The average number of N. seoulense in infected A. agrarius was the highest in spring (66.0 specimens), followed by autumn (15.2), winter (4.5), and summer (3.3). This study first confirms that A. agrarius is a natural definitive host for N. seoulense, and demonstrates that the infection rates and intensities vary seasonally and geographically.

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  • The genetic structure of populations of Isthmiophora melis (Schrank, 1788) (Digenea: Echinostomatidae). Does the host’s diet matter?
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    Journal of Helminthology.2023;[Epub]     CrossRef
  • Intestinal Helminthic Infections in Striped Field Mice,Apodemus agrarius, from Two Southern Regions of Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Hyeon-Je Song, Chung-Mo Kim, Gi-Jin Nam
    The Korean Journal of Parasitology.2014; 52(4): 419.     CrossRef
  • Trematodes Recovered in the Small Intestine of Stray Cats in the Republic of Korea
    Jong-Yil Chai, Young Yil Bahk, Woon-Mok Sohn
    The Korean Journal of Parasitology.2013; 51(1): 99.     CrossRef
  • Ecological surveillance of small mammals at Dagmar North Training Area, Gyeonggi Province, Republic of Korea, 2001-2005
    Heung Chul Kim, Terry A. Klein, Hae Ji Kang, Se Hun Gu, Sung Sil Moon, Luck Ju Baek, Sung Tae Chong, Monica L. O'Guinn, John S. Lee, Michael J. Turell, Jin-Won Song
    Journal of Vector Ecology.2011; 36(1): 42.     CrossRef
  • Echinostome Infections in the Striped-Field Mouse, Apodemus agrarius, and the Ussuri White-Toothed Shrew, Crocidura lasiura, Caught Near the Demilitarized Zone, Gyeonggi-do (Province), Republic of Korea
    Jong-Yil Chai, Jae-Hwan Park, Bong-Kwang Jung, Sang-Mee Guk, Jae-Lip Kim, Eun-Hee Shin, Terry A. Klein, Heung-Chul Kim, Sung-Tae Chong, Luck Ju Baek, Jin-Won Song
    The Korean Journal of Parasitology.2009; 47(3): 311.     CrossRef
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    Jong-Yil Chai, Eun-Hee Shin, Soon-Hyung Lee, Han-Jong Rim
    The Korean Journal of Parasitology.2009; 47(Suppl): S69.     CrossRef
  • A New Neodiplostomid (Digenea) From the Intestine of Chicks Infected with Metacercariae From the Grass Snake, Rhabdophis tigrina
    Eun-Hee Shin, Jae-Lip Kim, Jong-Yil Chai
    Journal of Parasitology.2008; 94(6): 1379.     CrossRef
  • Ecological surveillance of small mammals at Firing Points 10 and 60, Gyeonggi Province, Republic of Korea, 2001–2005
    Monica L. O'Guinn, Terry A. Klein, John S. Lee, Heung-Chul Kim, Luck-Ju Baek, Sung-Tae Chong, Michael J. Turell, Douglas A. Burkett, Anthony Schuster, In-Yong Lee, Suk-Hee Yi, William J. Sames, Ki-Joon Song, Jin-Won Song
    Journal of Vector Ecology.2008; 33(2): 370.     CrossRef
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Plagiorchis muris infection in Apodemus agrarius from northern Gyeonggi-do (Province) near the demilitarized zone
Jong-Yil Chai, Jae-Hwan Park, Sang-Mee Guk, Jae-Lip Kim, Hyo-Jin Kim, Won-Hee Kim, Eun-Hee Shin, Terry A. Klein, Heung-Chul Kim, Sung-Tae Chong, Jin-Won Song, Luck-Ju Baek
Korean J Parasitol 2007;45(2):153-156.
Published online June 20, 2007
DOI: https://doi.org/10.3347/kjp.2007.45.2.153

The small intestines of 6 species of rodents and 1 species of insectivore were examined seasonally for Plagiorchis muris infection in 3 different localities in northern Gyeonggi-do (Province), near the demilitarized zone (DMZ). A total of 1,496 animals, including 1,366 Apodemus agrarius, 54 Crocidura lasiura (insectivore), 32 Mus musculus, 28 Micronytus fortis, 9 Eothenomys regulus, 6 Micronys minutus, and 3 Cricetulus triton, were live-trapped at Yeoncheon-gun (n = 351), Paju-shi (804) and Pocheon-gun (343) at 3-mo intervals from December 2004 to September 2005. A total of 1,647 P. muris were collected from 72 (5.3%) A. agrarius. The infection rate was the highest in Pocheon-gun (8.2%), followed by Yeoncheon-gun (5.0%) and Paju-shi (4.2%). A higher infection rate was observed in A. agrarius captured during September (19.4%) than those captured during December (3.0%), June (2.6%), or April (0%). However, the worm burden was the highest in June (av. 32.1/animal), followed by September (24.7), December (4.0), and April (0). None of the other animal species were found infected with P. muris. The results reveal that A. agrarius is a natural definitive host for P. muris, and infection rates and worm burdens vary seasonally and geographically.

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  • Metabarcoding of bacteria and parasites in the gut of Apodemus agrarius
    Soo Lim Kim, Jun Ho Choi, Myung-hee Yi, Seogwon Lee, Myungjun Kim, Singeun Oh, In-Yong Lee, Bo-Young Jeon, Tai-Soon Yong, Ju Yeong Kim
    Parasites & Vectors.2022;[Epub]     CrossRef
  • Infections of Intestinal Helminth at Two Species of Field Mice, Apodemus agrarius and A. Peninsulae, in Gangwondo and Chungcheongnam-do, Korea
    Jae-Hyung Lee, Shuang Gong, Yung Chul Park, Hyun-Ju Kim, In-Wook Choi, Young-Ha Lee
    The Korean Journal of Parasitology.2018; 56(3): 301.     CrossRef
  • A molecular and ecological analysis of the trematodePlagiorchis elegansin the wood mouseApodemus sylvaticusfrom a periaquatic ecosystem in the UK
    K. Boyce, G. Hide, P.S. Craig, C. Reynolds, M. Hussain, A.J. Bodell, H. Bradshaw, A. Pickles, M.T. Rogan
    Journal of Helminthology.2014; 88(3): 310.     CrossRef
  • Intestinal Helminthic Infections in Striped Field Mice,Apodemus agrarius, from Two Southern Regions of Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Hyeon-Je Song, Chung-Mo Kim, Gi-Jin Nam
    The Korean Journal of Parasitology.2014; 52(4): 419.     CrossRef
  • Trematodes Recovered in the Small Intestine of Stray Cats in the Republic of Korea
    Jong-Yil Chai, Young Yil Bahk, Woon-Mok Sohn
    The Korean Journal of Parasitology.2013; 51(1): 99.     CrossRef
  • Intestinal Parasites among Wild Rodents in Northern Gangwon-do, Korea
    Young-Il Lee, Hee-Jang Pyeon, Min Seo
    The Korean Journal of Parasitology.2013; 51(5): 603.     CrossRef
  • The use of parasites as indicators of ecosystem health as compared to insects in freshwater lakes of the Inland Northwest
    John Shea, Gordon J. Kersten, Chris M. Puccia, Andy T. Stanton, Suzi N. Stiso, Erika S. Helgeson, Emily J. Back
    Ecological Indicators.2011;[Epub]     CrossRef
  • Fish-borne Parasitic Diseases
    Jong-Yil Chai
    Hanyang Medical Reviews.2010; 30(3): 223.     CrossRef
  • Foodborne Intestinal Flukes in Southeast Asia
    Jong-Yil Chai, Eun-Hee Shin, Soon-Hyung Lee, Han-Jong Rim
    The Korean Journal of Parasitology.2009; 47(Suppl): S69.     CrossRef
  • Echinostome Infections in the Striped-Field Mouse, Apodemus agrarius, and the Ussuri White-Toothed Shrew, Crocidura lasiura, Caught Near the Demilitarized Zone, Gyeonggi-do (Province), Republic of Korea
    Jong-Yil Chai, Jae-Hwan Park, Bong-Kwang Jung, Sang-Mee Guk, Jae-Lip Kim, Eun-Hee Shin, Terry A. Klein, Heung-Chul Kim, Sung-Tae Chong, Luck Ju Baek, Jin-Won Song
    The Korean Journal of Parasitology.2009; 47(3): 311.     CrossRef
  • 8,830 View
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Original Articles

A new endemic focus of Gymnophalloides seoi infection on Aphae Island, Shinan-gun, Jeollanam-do
Jae-Hwan Park, Sang-Mee Guk, Eun-Hee Shin, Hyo-Jin Kim, Jae-Lip Kim, Min Seo, Yun-Kyu Park, Jong-Yil Chai
Korean J Parasitol 2007;45(1):39-44.
Published online March 20, 2007
DOI: https://doi.org/10.3347/kjp.2007.45.1.39

A new endemic focus of Gymnophalloides seoi infection has been discovered on Aphae Island (Shinan-gun, Jeollanam-do), Republic of Korea. This area, which is referred to as Bokyong-ri, is a small seashore village located in the northern portion of the island. Fecal samples were collected from a total of 57 residents and examined by the Kato-Katz and formalin-ether sedimentation techniques. Helminth eggs were detected in 37 samples (64.9%); 33 samples were positive for G. seoi eggs (57.9%), 4 for Pygidiopsis summa (7.0%), 13 for other heterophyids (22.8%), 1 for Clonorchis sinensis (1.7%), and 1 for Trichuris trichiura (1.7%). Women (70.4%) revealed higher rates of G. seoi infection than did men (46.7%), and individuals older than 50 years of age also evidenced higher rates of G. seoi infection than in other age groups (P< 0.05). In worm collection from 13 G. seoi egg positive cases, G. seoi (total 86,558 specimens), Heterophyes nocens (278), Stictodora sp. (10), Heterophyopsis continua (3), P. summa (3), and unidentified flukes (42) were collected. Oysters, the source of G. seoi infection, were collected from an area proximal to the village and 50 were examined for metacercariae; 47 (94%) were found infected and the observed metacercarial density was 9.5 ± 8.9 per oyster. The results of this study indicate that Bokyong-ri is a new endemic area of G. seoi infection, with high rates of infection in humans and oysters.

Citations

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  • Survey of Gymnophalloides seoi Metacercariae in Natural and Cultured Oysters from Several Western Coastal Areas, Korea
    Taehee Chang, Bong-Kwang Jung, Hyemi Song, Jaeeun Cho, Sooji Hong, Keon-Hoon Lee, Eui-Hyug Hoang, Jisu Kang, Jini Lim, Hana Lee, Jong-Yil Chai
    The Korean Journal of Parasitology.2019; 57(6): 705.     CrossRef
  • Pygidiopsis summa (Digenea: Heterophyidae): Status of Metacercarial Infection in Mullets from Coastal Areas in the Republic of Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Won-Ja Lee, Mi-Yeoun Park, Soon-Won Lee, Seung-Bong Choi, Beom-Nyung Huh, Won-Seok Seok
    The Korean Journal of Parasitology.2016; 54(4): 497.     CrossRef
  • Korean molluscs as auxiliary hosts for parasites: A study of implications for pathogen transmission in a changing climate
    Gab-Man Park
    The Korean Journal of Malacology.2012; 28(1): 13.     CrossRef
  • Emerging Parasitic Diseases in Korea
    Jong-Yil Chai
    Journal of the Korean Medical Association.2007; 50(11): 946.     CrossRef
  • 8,805 View
  • 74 Download
  • Crossref
A new endemic focus of Heterophyes nocens and other heterophyid infections in a coastal area of Gangjin-gun, Jeollanam-do
Jae-Hwan Park, Jae-Lip Kim, Eun-Hee Shin, Sang-Mee Guk, Yun-Kyu Park, Jong-Yil Chai
Korean J Parasitol 2007;45(1):33-38.
Published online March 20, 2007
DOI: https://doi.org/10.3347/kjp.2007.45.1.33

To know the prevalence of heterophyid trematodes among inhabitants of a southern coastal village, i.e., Sacho-ri, Gangjin-gun, Jeollanam-do (Province), 82 stool samples were examined on helminth eggs and protozoan cysts using Kato-Katz and formalin-ether sedimentation techniques. Total 33 people (40.2%) were positive for trematodes (Heterophyes nocens; 15 people, Pygidiopsis summa; 3, Metagonimus sp.; 4, Clonorchis sinensis; 7, Gymnophalloides seoi; 6) and/or protozoa (Entamoeba coli; 3). Among intestinal trematode egg positive cases, 17 were treated with praziquantel and their whole diarrheic stools were collected after purgation. Adult flukes of H. nocens (number of specimens = 1,294), P. summa (386), Stellantchasmus falcatus (5), Stictodora lari (4), and Heterophyopsis continua (1) were collected using a stereomicroscope. To know the source of human H. nocens infections in this village, metacercarial infections in mullets (10) were examined and most H. nocens metacercariae (101/105, 96.2%) were found in the trunk portion. From above results, the surveyed coastal village has been newly known as an endemic focus of human H. nocens infection and consuming raw mullets was the presumable source of human heterophyid infections.

Citations

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  • Infection characteristics of Metagonimus species (Digenea: Heterophyidae) metacercariae in fish from major rivers of Korea
    Woon-Mok Sohn
    Parasites, Hosts and Diseases.2024; 62(1): 1.     CrossRef
  • Infection Characteristics of Clonorchis sinensis Metacercariae in Fish from Republic of Korea
    Woon-Mok Sohn
    The Korean Journal of Parasitology.2022; 60(2): 79.     CrossRef
  • Infection Status with Clonorchis sinensis Metacercariae in Fish from Tamjin-gang (River) in Jeollanam-do, Republic of Korea
    Ki-Bok Yoon, Hyun-Cheol Lim, Doo Young Jeon, Sook Park, Shin-Hyeong Cho, Jung-Won Ju, Sung-Shik Shin, Byoung-Kuk Na, Woon-Mok Sohn
    The Korean Journal of Parasitology.2018; 56(2): 183.     CrossRef
  • Infections with Zoonotic Trematode Metacercariae in Yellowfin Goby, Acanthogobius flavimanus, from Coastal Areas of Republic of Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Jung-Won Ju, Soon-Won Lee, Won-Seok Seok
    The Korean Journal of Parasitology.2018; 56(3): 259.     CrossRef
  • Infection Status with Metagonimus spp. Metacercariae in Fishes from Seomjin-gang and Tamjin-gang in Republic of Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Jung-Won Ju, Cheon-Hyeon Kim, Ki-Bok Yoon
    The Korean Journal of Parasitology.2018; 56(4): 351.     CrossRef
  • Fishborne zoonotic heterophyid infections: An update
    Jong-Yil Chai, Bong-Kwang Jung
    Food and Waterborne Parasitology.2017; 8-9: 33.     CrossRef
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    M. A. Ibrahim, A. E. Abdel-Ghany, G. K. Abdel-Latef, S. A. Abdel-Aziz, S. M. Aboelhadid
    Parasitology Research.2016; 115(6): 2439.     CrossRef
  • Pygidiopsis summa (Digenea: Heterophyidae): Status of Metacercarial Infection in Mullets from Coastal Areas in the Republic of Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Won-Ja Lee, Mi-Yeoun Park, Soon-Won Lee, Seung-Bong Choi, Beom-Nyung Huh, Won-Seok Seok
    The Korean Journal of Parasitology.2016; 54(4): 497.     CrossRef
  • Stellantchasmus falcatus (Digenea: Heterophyidae) in Cambodia: Discovery of Metacercariae in Mullets and Recovery of Adult Flukes in an Experimental Hamster
    Jong-Yil Chai, Woon-Mok Sohn, Byoung-Kuk Na, Hoo-Gn Jeoung, Muth Sinuon, Duong Socheat
    The Korean Journal of Parasitology.2016; 54(4): 537.     CrossRef
  • Infection Status of Estuarine Fish and Oysters with Intestinal Fluke Metacercariae in Muan-gun, Jeollanam-do, Korea
    Shin-Hyeong Cho, In-Sang Kim, Eun-Jung Hwang, Tong-Soo Kim, Byoung-Kuk Na, Woon-Mok Sohn
    The Korean Journal of Parasitology.2012; 50(3): 215.     CrossRef
  • Epidemiological Survey on the Infection of Intestinal Flukes in Residents of Muan-gun, Jeollanam-do, the Republic of Korea
    Shin-Hyeong Cho, Pyo-Yun Cho, Dong-Min Lee, Tong-Soo Kim, In-Sang Kim, Eun-Jung Hwang, Byoung-Kuk Na, Woon-Mok Sohn
    The Korean Journal of Parasitology.2010; 48(2): 133.     CrossRef
  • Foodborne Intestinal Flukes in Southeast Asia
    Jong-Yil Chai, Eun-Hee Shin, Soon-Hyung Lee, Han-Jong Rim
    The Korean Journal of Parasitology.2009; 47(Suppl): S69.     CrossRef
  • Trends in parasitic diseases in the Republic of Korea
    Eun-Hee Shin, Sang-Mee Guk, Hyo-Jin Kim, Soon-Hyung Lee, Jong-Yil Chai
    Trends in Parasitology.2008; 24(3): 143.     CrossRef
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    Jong-Yil Chai
    Journal of the Korean Medical Association.2007; 50(11): 946.     CrossRef
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Brief Communication

A survey of cryptosporidiosis among 2,541 residents of 25 coastal islands in Jeollanam-do (Province), Republic of Korea
Jae-Hwan Park, Hyo-Jin Kim, Sang-Mee Guk, Eun-Hee Shin, Jae-Lip Kim, Han-Jong Rim, Soon-Hyung Lee, Jong-Yil Chai
Korean J Parasitol 2006;44(4):367-372.
Published online December 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.4.367

In order to determine the distribution and prevalence of human cryptosporidiosis on western and southern coastal islands of Jeollanam-do (Province), fecal samples were collected from 2,541 people residing on 25 islands, 13 in the western coasts and 12 in the southern coasts, during July and August 2000. Fecal smears were prepared following formalin-ether sedimentation of the samples and stained by a modified acid-fast procedure. The presence of Cryptosporidium oocysts was determined by light microscopy. Cryptosporidium oocysts were detected in 38 specimens (1.5%). The oocyst positive rate varied (0-6.0%) according to island; the highest was detected on Oenarodo (6.0%), followed by Naenarodo (5.6%) and Nakwoldo (5.4%). The majority (35 persons, 94.6%) of Cryptosporidium-infected individuals were older than 50 years of age. Men (22/1,159; 1.9%) were infected at a higher rate than women (16/1,382; 1.2%). The results of the present survey indicate that human Cryptosporidium infections (due to Cryptosporidium hominis and/or C. parvum) are maintained at a relatively low prevalence on coastal islands of Jeollanam-do, Republic of Korea.

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    Medical Laboratory Journal.2021; 15(1): 40.     CrossRef
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    Sun Huh
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    Ayman A. El-Badry, Samar S. El Sayed, Rafiaa R. Hussein, Youssef M. Said, Abeer S. Al-Antably, Marwa A. Hassan
    Heliyon.2019; 5(8): e02228.     CrossRef
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    Asis Khan, Jahangheer S. Shaik, Michael E. Grigg
    Acta Tropica.2018; 184: 1.     CrossRef
  • Health Risk Assessment of Cryptosporidium in Tap Water in Korea
    Mok-Young Lee, Sang-Jung Park, Eun-Joo Cho, Su-Jeong Park, Sun-Hee Han, Oh-Sang Kwon
    Korean Journal of Environmental Health Sciences.2013; 39(1): 32.     CrossRef
  • Development of a Diagnostic Kit to Detect Cryptosporidium parvum and Giardia lamblia
    Hyeng-Il Cheun, Byung-Suk Chung, Da-Won Ma, Bo-La Goo, Shin-Hyeong Cho, Mi-jung Ji, Won-Ja Lee
    Osong Public Health and Research Perspectives.2013; 4(3): 146.     CrossRef
  • Epidemiological Characteristics of the First Water-Borne Outbreak of Cryptosporidiosis in Seoul, Korea
    Shinje Moon, Wooseok Kwak, Sangwon Lee, Won Kim, Jaeyeon Oh, Seung-Ki Youn
    Journal of Korean Medical Science.2013; 28(7): 983.     CrossRef
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    Katymilla Guimarães Girotto, Daliane Faria Grama, Maria Júlia Rodrigues da Cunha, Elaine Silva Marques Faria, Jean Ezequiel Limongi, Rogério de Melo Costa Pinto, Márcia Cristina Cury
    Revista do Instituto de Medicina Tropical de São Paulo.2013; 55(1): 19.     CrossRef
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    E. Budu‐Amoako, S. J. Greenwood, B. R. Dixon, L. Sweet, L. Ang, H. W. Barkema, J. T. McClure
    Zoonoses and Public Health.2012; 59(6): 424.     CrossRef
  • CysQ ofCryptosporidium parvum, a Protozoa, May Have Been Acquired from Bacteria by Horizontal Gene Transfer
    Ji Young Lee, Sangsoo Kim
    Genomics & Informatics.2012; 10(1): 9.     CrossRef
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    Sung Shik Shin
    Hanyang Medical Reviews.2010; 30(3): 246.     CrossRef
  • Cryptosporidium parvum in Korea: Prevalence in Individuals Residing in Three Major River Valleys and Genetic Characteristics of the Isolates
    Hyeng-Il CHEUN, Shin-Hyeong CHO, Yi-Young LIM, Byung-Chul LEE, Jung-Yeon KIM, Jung-Won JU, Byoung-Kuk NA, Isao KIMATA, Jae-Ran YU, Tong-Soo KIM
    Journal of Veterinary Medical Science.2010; 72(2): 167.     CrossRef
  • Genetic polymorphism in Cryptosporidium species: An update
    Judit Plutzer, Panagiotis Karanis
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  • A Hospital-Based Serological Survey of Cryptosporidiosis in the Republic of Korea
    Jong-Kyu Lee, Eun-Taek Han, Sun Huh, Woo-Yoon Park, Jae-Ran Yu
    The Korean Journal of Parasitology.2009; 47(3): 219.     CrossRef
  • Antibody Responses to Cryptosporidium Antigen in HIV-positive Patients in the Republic of Korea
    Sang-Mee Guk, Jong-Yil Chai, Yung-Oh Shin, Min Seo
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  • Trends in parasitic diseases in the Republic of Korea
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    Trends in Parasitology.2008; 24(3): 143.     CrossRef
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    Mohammad Mirzaei
    The Korean Journal of Parasitology.2007; 45(2): 133.     CrossRef
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    Jong-Yil Chai
    Journal of the Korean Medical Association.2007; 50(11): 946.     CrossRef
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Case Reports

A case of histologically diagnosed tick infestation on the scalp of a Korean child
Sun Hee Chang, Jae-Hwan Park, Ji Eun Kwak, Mee Joo, Hanseong Kim, Je G. Chi, Sung-Tae Hong, Jong-Yil Chai
Korean J Parasitol 2006;44(2):157-161.
Published online June 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.2.157

A scalp mass surgically excised from a 4-year-old Korean boy was identified as a tick through histological observations. In sections of the mass, characteristic features of a tick, including its gross contour, cuticular structures, well developed musculature and salivary glands, and the capitulum, were discovered. In particular, the capitulum is anteriorly protruded, which strongly suggests that the specimen be a hard tick of family Ixodidae. However, the present histological features were not enough to determine the genus and species of the tick, because information on sectional morphologies of different tick species is unavailable. This is a rare case of tick infestation on the scalp diagnosed in histological sections.

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A surgically confirmed case of breast sparganosis showing characteristic mammography and ultrasonography findings
Jae-Hwan Park, Jee-Won Chai, Nariya Cho, Nam-Sun Paek, Sang-Mee Guk, Eun-Hee Shin, Jong-Yil Chai
Korean J Parasitol 2006;44(2):151-156.
Published online June 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.2.151

A case of breast sparganosis was confirmed by surgical excision of a worm (fragmented into 5 pieces) in a 59-year-old Korean woman suffering from a palpable mass in the left breast. Mammography and ultrasonography characteristically revealed the presence of several well-defined, isodense and hypoechoic tubular masses, in the upper quadrant of the left breast, each mass consisting of a continuous cord- or worm-like structure. During surgery, a long segment of an actively moving sparganum of Spirometra sp. and 4 small fragments of the same worm, giving a total length of 20.3 cm, were extracted from the upper outer quadrant of the left breast and the axillary region. The infection source remains unclear, because the patient denied ingesting any snake or frog meat or drinking untreated water.

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Original Articles

Genotype analysis of Cryptosporidium spp. prevalent in a rural village in Hwasun-gun, Republic of Korea
Jae-Hwan Park, Sang-Mee Guk, Eun-Taek Han, Eun-Hee Shin, Jae-Lip Kim, Jong-Yil Chai
Korean J Parasitol 2006;44(1):27-33.
Published online March 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.1.27

Two species of Cryptosporidium are known to infect man; C. hominis which shows anthroponotic transmission between humans, and C. parvum which shows zoonotic transmission between animals or between animals and man. In this study, we focused on identifying genotypes of Cryptosporidium prevalent among inhabitants and domestic animals (cattle and goats), to elucidate transmittal routes in a known endemic area in Hwasun-gun, Jeollanam-do, Republic of Korea. The existence of Cryptosporidium oocysts was confirmed using a modified Ziehl-Neelsen stain. Human infections were found in 7 (25.9%) of 27 people examined. Cattle cryptosporidiosis cases constituted 7 (41.2%) of 17 examined, and goat cases 3 (42.9%) of 7 examined. Species characterizations were performed on the small subunit of the rRNA gene using both PCR-RFLP and sequence analysis. Most of the human isolates were mixtures of C. hominis and C. parvum genotypes and similar PCR-RFLP patterns were observed in cattle and goat isolates. However, sequence analyses identified only C. hominis in all isolates examined. The natural infection of cattle and goats with C. hominis is a new and unique finding in the present study. It is suggested that human cryptosporidiosis in the studied area is caused by mixtures of C. hominis and C. parvum oocysts originating from both inhabitants and domestic animals.

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Prevalence of Gymnophalloides seoi infection in coastal villages of Haenam-gun and Yeongam-gun, Republic of Korea
Sang-Mee Guk, Jae-Hwan Park, Eun-Hee Shin, Jae-Lip Kim, Aifen Lin, Jong-Yil Chai
Korean J Parasitol 2006;44(1):1-5.
Published online March 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.1.1

One coastal village in Haenam-gun and two in Yeongam-gun, Jeollanam-do were surveyed for intestinal parasite infections by fecal examination. The egg positive rates of Gymnophalloides seoi were high, 24.1% (14/58) in Haenam-gun and 9.3% (11/118) in Yeongam-gun. The egg positive rates of heterophyids, including Heterophyes nocens, and of Clonorchis sinensis were 10.3% and 6.9% in Haenam-gun, and 14.4% and 8.5% in Yeongam-gun, respectively. After praziquantel treatment and purgation, a total of 37,761 fluke specimens were recovered from 17 patients; 11 in Haenam-gun and 6 in Yeongam-gun. Gymnophalloides seoi was the most commonly recovered species, with 37,489 specimens in total (2,205 per person). Other recovered flukes included Heterophyes nocens, Stictodora fuscata, Heterophyopsis continua, Pygidiopsis summa, and undetermined species. These results indicate that the areas surveyed are new endemic foci of G. seoi.

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A survey of Enterobius vermicularis infection among children on western and southern coastal islands of the Republic of Korea
Jae-Hwan Park, Eun-Taek Han, Won-Hee Kim, Eun-Hee Shin, Sang-Mee Guk, Jae-Lip Kim, Jong-Yil Chai
Korean J Parasitol 2005;43(4):129-134.
Published online December 20, 2005
DOI: https://doi.org/10.3347/kjp.2005.43.4.129

To determine the status of Enterobius vermicularis infection among children living on western and southern coastal islands of the Republic of Korea, children (3-10 years) in 39 kindergartens and primary schools were examined using the cello-tape anal swab method, during July and August 2000. Of 1,661 children examined, 307 (18.5%) were found to be positive for E. vermicularis eggs. The highest infection rate (59.3%) was found in a kindergarten and a branch school of Shinyang primary school on Chujado, Jeju-do (Province). Remarkable differences in egg positive rates were observed in different localities. The egg positive rate for boys (21.3%) was significantly higher than that of girls (15.4%) (P = 0.02). However, positive rates were not significantly dependent on age. The results of the present study show that E. vermicularis infection is highly prevalent among pre-school and primary school children living on the western and southern coastal islands of the Republic of Korea, and indicate the need for efforts to control this infection.

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Brief Communication

A new method for concentration of proteins in the calcareous corpuscles separated from the spargana of Spirometra erinacei
Yun-Kyu Park, Jae-Hwan Park, Sang-Mee Guk, Eun-Hee Shin, Jong-Yil Chai
Korean J Parasitol 2005;43(3):119-122.
Published online September 20, 2005
DOI: https://doi.org/10.3347/kjp.2005.43.3.119

Calcareous corpuscles are a characteristic structure found in larval and adult stage cestodes. These corpuscles are known to contain several protein components and to possess protein-binding activity. However, the proteins bound to calcareous corpuscles in situ have not been studied. The present study was undertaken to identify the proteins on calcareous corpuscles. Calcareous corpuscles were purified from the plerocercoids (= spargana) of Spirometra erinacei, and serially dissolved using 0.1 M sulfamic acid solution. Collected supernatants were examined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and silver staining. The results showed that only the fraction remaining after the 19th dissolved fraction contained proteins. A total of 20 protein molecules were detected in gel, with major bands at 56, 53, 46, 40, 35, 29, 28, 24.5, 21, 19, 16, 13, 10 and 8 kDa. In particular, the proteins corresponding to the 21 and 16 kDa bands were most abundant. Our results demonstrated for the first time the protein contents of the calcareous corpuscles of spargana. Further studies on the functions of these proteins are required.

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    Jae-Hwan Kim, Young Ju Kim, Woon-Mok Sohn, Young Mee Bae, Sung-Tae Hong, Min-Ho Choi
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Original Article

Genetic characteristics of the Korean isolate KI-1 of Toxoplasma gondii
Aifen Lin, Eun-Hee Shin, Tae-Yun Kim, Jae-Hwan Park, Sang-Mee Guk, Jong-Yil Chai
Korean J Parasitol 2005;43(1):27-32.
Published online March 20, 2005
DOI: https://doi.org/10.3347/kjp.2005.43.1.27

Toxoplasma gondii tachyzoites were isolated from an ocular patient in the Republic of Korea and maintained in the laboratory (designated KI-1). In the present study, its genotype was determined by analyzing dense granule antigen 6 (GRA6) gene and surface antigen 2 (SAG2) gene as typing markers. Digestion of the amplification products of GRA6 and of the 5' and 3' ends of SAG2, respectively, with Mse I, Sau3A I, and Hha I, revealed that KI-1 is included in the genotype I, which includes the worldwide virulent RH strain. In addition, when the whole sequences of the coding regions of SAG1, rhoptry antigen 1 (ROP1), and GRA8 genes of KI-1 were compared with those of RH, minor nucleotide polymorphisms and amino acid substitutions were identified. These results show that KI-1 is a new geographical strain of T. gondii that can be included in the genotype I.

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    Bong-Kwang Jung, Sang-Eun Lee, Hyemi Lim, Jaeeun Cho, Deok-Gyu Kim, Hyemi Song, Min-Jae Kim, Eun-Hee Shin, Jong-Yil Chai
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    Shantaveer Biradar, Buddhi Saravanan, Anup Tewari, Chirukandoth Sreekumar, Muthu Sankar, Naduvanahalli Sudhakar
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    Eun-Hee Shin, Yeoun Sook Chun, Won-Hee Kim, Jae-Lip Kim, Kyoung-Ho Pyo, Jong-Yil Chai
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    Si-Hwan Choi, Tae Yun Kim, Sung Goo Park, Guang-Ho Cha, Dae-Whan Shin, Jong-Yil Chai, Young-Ha Lee
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    Susana Sousa, Daniel Ajzenberg, Maggy Marle, Dominique Aubert, Isabelle Villena, José Correia da Costa, Marie-Laure Dardé
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    Juan-Hua Quan, Tae Yun Kim, In-Uk Choi, Young-Ha Lee
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    Eun-Hee Shin, Dong-Hee Kim, Aifen Lin, Jo-Woon-Yi Lee, Hyo-Jin Kim, Myoung-Hee Ahn, Jong-Yil Chai
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Brief Communications

Genotype and animal infectivity of a human isolate of Cryptosporidium parvum in the Republic of Korea
Sang-Mee Guk, Tai-Soon Yong, Soon-Jung Park, Jae-Hwan Park, Jong-Yil Chai
Korean J Parasitol 2004;42(2):85-89.
Published online June 20, 2004
DOI: https://doi.org/10.3347/kjp.2004.42.2.85

Cryptosporidium parvum oocysts were isolated from a child suffering from acute gastroenteritis and successfully passaged in a calf and mice (designated hereafter SNU-H1) in the Republic of Korea; its molecular genotype has been analyzed. The GAG microsatellite region was amplified by a polymerase chain reaction (PCR), with a 238 base pair product, which is commonly displayed in C. parvum. The isolate was shown to be a mixture of the genotypes 1 (anthroponotic) and 2 (zoonotic). To study its infectivity in animals, 2 calves and 3 strains of mice were infected with the SNU-H1; in these animals, the propagation of both genotypes was successful. In immunosuppressed (ImSP) BALB/c and C57BL/6 mice the number of oocysts decreased after day 10 post-infection (PI); but in ImSP ICR mice, they remained constant until day 27 PI. The results show that both the C. parvum genotypes 1 and 2 can be propagated in calves and ImSP mice.

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Clonorchis sinensis metacercarial infection in the pond smelt Hypomesus olidus and the minnow Zacco platypus collected from the Soyang and Daechung Lakes
Jae-Hwan Park, Sang-Mee Guk, Tae-Yun Kim, Eun-Hee Shin, Aifen Lin, Ji-Yeon Park, Jae-Lip Kim, Sung-Tae Hong, Jong-Yil Chai
Korean J Parasitol 2004;42(1):41-44.
Published online March 20, 2004
DOI: https://doi.org/10.3347/kjp.2004.42.1.41

The pond smelt Hypomesus olidus and minnow Zacco platypus were collected from the Soyang and Daechung Lakes in January 2003, and their metacercarial infections was examined by the muscle compression and artificial digestion techniques. In the Soyang Lake, 161 metacercariae of Clonorchis sinensis (0.35 per fish) were harvested from 459 pond smelts examined. Also, 13 metacercariae of C. sinensis (0.43 per fish), 1 of Metagonimus sp., 4 of Echinostoma sp., 148 of Centrocestus armatus and 44 unidentified species were collected from 30 minnows. In the Daechung Lake, 369 metacercariae of C. sinensis (3.69 per fish) and 51 unidentified species were recovered from 100 pond smelts. The metacercariae of C. sinensis were fed to experimental rats, in which the adult flukes were identified. The pond smelts and minnows collected from the Soyang and Daechung Lakes were verified to be the second intermediate hosts and the sources of human C. sinensis infection.

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    The Korean Journal of Parasitology.2011; 49(4): 385.     CrossRef
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    Daixiong Chen, Jieyun Chen, Ji Huang, Xueying Chen, Dana Feng, Baofang Liang, Yuchuan Che, Xiaodan Liu, Cuihua Zhu, Xiaomin Li, Haoxian Shen
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    Jakob Skov, Per W. Kania, Anders Dalsgaard, Thomas R. Jørgensen, Kurt Buchmann
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    Shin-Hyeong Cho, Woon-Mok Sohn, Sung-Shik Shin, Hyeon-Je Song, Taek-Gyun Choi, Chang-Mi Oh, Yoon Kong, Tong-Soo Kim
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    Jong-Yil Chai, K. Darwin Murrell, Alan J. Lymbery
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Original Article

Effects of anti-allergic drugs on intestinal mastocytosis and worm expulsion of rats infected with Neodiplostomum seoulense
Eun-Hee Shin, Tae-Heung Kim, Sung-Jong Hong, Jae-Hwan Park, Sang-Mee Guk, Jong-Yil Chai
Korean J Parasitol 2003;41(2):81-87.
Published online June 20, 2003
DOI: https://doi.org/10.3347/kjp.2003.41.2.81

The effects of anti-allergic drugs on intestinal mastocytosis and the expulsion of Neodiplostomum seoulense were observed in Sprague-Dawley rats, after oral infection with 500 metacercariae. The drugs used were hydroxyzine (a histamine receptor H1 blocker), cimetidine (a H2 blocker), cyclosporin-A (a helper T-cell suppressant), and prednisolone (a T- and B-cell suppressant). Infected, but untreated controls, and uninfected controls, were prepared. Worm recovery rate and intestinal mastocytosis were measured on weeks 1, 2, 3, 5, and 7 post-infection. Compared with the infected controls, worm expulsion was significantly (P < 0.05) delayed in hydroxyzine- and cimetidine-treated rats, despite mastocytosis being equally marked in the duodenum of all three groups. In the cyclosporin-A- and prednisolone-treated groups, mastocytosis was suppressed, but worm expulsion was only slightly delayed, without statistical significance. Our results suggest that binding of histamine to its receptors on intestinal smooth muscles is more important in terms of the expulsion of N. seoulense from rats than the levels of histamine alone, or mastocytosis.

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    Asmaa M. I. Abuzeid, Mahmoud M. Hefni, Yue Huang, Long He, Tingting Zhuang, Guoqing Li
    Frontiers in Veterinary Science.2022;[Epub]     CrossRef
  • Increased Intestinal Epithelial Cell Turnover and Intestinal Motility in Gymnophalloides seoi-Infected C57BL/6 Mice
    Sang Hyub Lee, Bong-Kwang Jung, Jae-Hwan Park, Eun-Hee Shin, Jong-Yil Chai
    The Korean Journal of Parasitology.2014; 52(3): 273.     CrossRef
  • Mast cell histamine promotes the immunoregulatory activity of myeloid-derived suppressor cells
    Rebecca K Martin, Sheinei J Saleem, Lauren Folgosa, Hannah B Zellner, Sheela R Damle, Giang-Kim T Nguyen, John J Ryan, Harry D Bear, Anne-Marie Irani, Daniel H Conrad
    Journal of Leukocyte Biology.2014; 96(1): 151.     CrossRef
  • Foodborne Intestinal Flukes in Southeast Asia
    Jong-Yil Chai, Eun-Hee Shin, Soon-Hyung Lee, Han-Jong Rim
    The Korean Journal of Parasitology.2009; 47(Suppl): S69.     CrossRef
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Brief Communication

Apical membrane antigen-1 (AMA-1) gene sequences of re-emerging Plasmodium vivax in South Korea
Eun-Taek Han, Jae-Hwan Park, Eun-Hee Shin, Min-Ho Choi, Myoung-Don Oh, Jong-Yil Chai
Korean J Parasitol 2002;40(3):157-162.
Published online September 30, 2002
DOI: https://doi.org/10.3347/kjp.2002.40.3.157

Plasmodium vivax malaria re-emerged in South Korea in 1993, and epidemics continue since then. We examined genetic variation in the region encompassing the apical membrane antigen-1 (PvAMA-1) of the parasites by DNA sequencing of the 22 re-emerging P. vivax isolates. The genotype of the PvAMA-1, which was based on sequence data previously reported for the polymorphic regions, showed that two haplotypes were present at one polymorphic site. Compared with reported data, the two types, SKOR type I and type II, were similar to Chinese CH-10A and CH-05A isolates, respectively. Thus, the present study showed that two genotypes of AMA-1 genes coexist in the re-emerging Korean P. vivax.

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  • Molecular Characterization of Plasmodium Species to Strengthen Malaria Surveillance in Migrant Populations in Honduras
    Ashley Godoy, Kevin Euceda, Alejandra Pinto, Hugo O. Valdivia, Lesly Chaver, Gloria Ardon, Gustavo Fontecha
    Tropical Medicine and Infectious Disease.2025; 10(10): 292.     CrossRef
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    Young Yil Bahk, Jeonga Kim, Seong Kyu Ahn, Byoung-Kuk Na, Jong-Yil Chai, Tong-Soo Kim
    The Korean Journal of Parasitology.2018; 56(6): 545.     CrossRef
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    Ram Das, Ramesh C. Dhiman, Deepali Savargaonkar, Anupkumar R. Anvikar, Neena Valecha
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    Andrea M McCollum, Valeria Soberon, Carola J Salas, Meddly L Santolalla, Venkatachalam Udhayakumar, Ananias A Escalante, Paul CF Graf, Salomon Durand, Cesar Cabezas, David J Bacon
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  • Population genetic structure and polymorphism analysis of gene encoding apical membrane antigen-1 (AMA-1) of Iranian Plasmodium vivax wild isolates
    Sedigheh Zakeri, Hengameh Sadeghi, Akram Abouie Mehrizi, Navid Dinparast Djadid
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    Ana Cecilia Lopez, Andres Ortiz, Jorge Coello, Wilfredo Sosa-Ochoa, Rosa E Mejia Torres, Engels I Banegas, Irina Jovel, Gustavo A Fontecha
    Malaria Journal.2012;[Epub]     CrossRef
  • Genetic diversity of the malaria vaccine candidate merozoite surface protein 1 gene of Plasmodium vivax field isolates in Republic of Korea
    Eun-Taek Han, Yue Wang, Chae Seung Lim, Jun Hwi Cho, Jong-Yil Chai
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  • CD8+T-cell Activation in Mice Injected with a Plasmid DNA Vaccine Encoding AMA-1 of the Reemerging KoreanPlasmodium vivax
    Hyo-Jin Kim, Bong-Kwang Jung, Jin-Joo Lee, Kyoung-Ho Pyo, Tae Yun Kim, Byung-il Choi, Tae Woo Kim, Hajime Hisaeda, Kunisuke Himeno, Eun-Hee Shin, Jong-Yil Chai
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  • Molecular markers and genetic diversity of Plasmodium vivax
    Cristiana Ferreira Alves de Brito, Marcelo Urbano Ferreira
    Memórias do Instituto Oswaldo Cruz.2011; 106(suppl 1): 12.     CrossRef
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    Seung-Young Hwang, So-Hee Kim, Weon-Gyu Kho
    The Korean Journal of Parasitology.2009; 47(Suppl): S51.     CrossRef
  • Plasmodium vivax: Sequence polymorphism and effect of natural selection at apical membrane antigen 1 (PvAMA1) among Indian population
    Ankur Thakur, Mohammad Tauqeer Alam, Hema Bora, Punit Kaur, Yagya D. Sharma
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    Priscila Grynberg, Cor Jesus F Fontes, Austin L Hughes, Érika M Braga
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  • Plasmodium vivax: Genetic diversity of the apical membrane antigen-1 (AMA-1) in isolates from India
    Vidya Rajesh, M. Elamaran, S. Vidya, M. Gowrishankar, Dhanpat Kochar, Ashis Das
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    Weon-Gyu Kho
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  • Reemerging vivax malaria: changing patterns of annual incidence and control programs in the Republic of Korea
    Eun-Taek Han, Duk-Hyoung Lee, Ki-Dong Park, Won-Seok Seok, Young-Soo Kim, Takafumi Tsuboi, Eun-Hee Shin, Jong-Yil Chai
    The Korean Journal of Parasitology.2006; 44(4): 285.     CrossRef
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Original Article
A nationwide survey of the prevalence of human Gymnophalloides seoi infection on western and southern coastal islands in the Republic of Korea
Jong-Yil Chai, Jae-Hwan Park, Eun-Taek Han, Eun-Hee Shin, Jae-Lip Kim, Kwang-Seon Hong, Han-Jong Rim, Soon-Hyung Lee
Korean J Parasitol 2001;39(1):23-30.
Published online March 31, 2001
DOI: https://doi.org/10.3347/kjp.2001.39.1.23

A nationwide survey was performed to know the distribution and prevalence of human Gymnophalloides seoi infection on western and southern coastal islands in the Republic of Korea. A total of 4,178 fecal specimens were collected from residents on 45 (24 western and 21 southern) islands, and examined by Kato-Katz and formalin-ether sedimentation techniques. Eggs of G. seoi were detected from 160 (3.8%) people living on 22 (13 western and 9 southern) islands. The prevalence varied by the location of islands; higher on western islands than on southern islands. The highest prevalence was found on Amtaedo (25.3%), followed by Cheungdo (25.0%), and Anchwado (20.9%) (Shinan-gun). A little lower prevalence was observed on Munyodo (13.3%), Shinshido (12.9%), and Sonyudo (10.3%) (Kunsan-shi). Of the remaining islands, the regions showing the prevalence greater than 5% included Kohado, Dallido (Mokpo-shi), Pyeongildo, Kogumdo (Wando-gun), and Keogumdo (Kohung-gun). A strong age predilection was noted (p < 0.05); 95% of the infected people were over 40 years old. Females showed a little higher prevalence than males. The results indicate that human G. seoi infection is more widely distributed than previously considered. Nine of 11 islands (excluding the 2 known areas Munyodo and Sunyudo) that showed greater prevalence than 5% are regarded as new endemic foci of G. seoi.

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    The Korean Journal of Parasitology.2016; 54(6): 809.     CrossRef
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    Min Seo, Adauto Araujo, Karl Reinhard, Jong Yil Chai, Dong Hoon Shin
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    Sang Hyub Lee, Bong-Kwang Jung, Jae-Hwan Park, Eun-Hee Shin, Jong-Yil Chai
    The Korean Journal of Parasitology.2014; 52(3): 273.     CrossRef
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    Young-Eun Kim, Hee Jae Huh, Yu-Yean Hwang, Nam Yong Lee
    Annals of Clinical Microbiology.2013; 16(3): 134.     CrossRef
  • Sixteenth CenturyGymnophalloides seoiInfection on the Coast of the Korean Peninsula
    Dong Hoon Shin, Chang Seok Oh, Jong-Yil Chai, Min Ju Ji, Hye-Jung Lee, Min Seo
    Journal of Parasitology.2012; 98(6): 1283.     CrossRef
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    Jong-Yil Chai, Eun-Hee Shin, Soon-Hyung Lee, Han-Jong Rim
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  • Trends in parasitic diseases in the Republic of Korea
    Eun-Hee Shin, Sang-Mee Guk, Hyo-Jin Kim, Soon-Hyung Lee, Jong-Yil Chai
    Trends in Parasitology.2008; 24(3): 143.     CrossRef
  • Gymnophalloides seoi Eggs from the Stool of a 17th Century Female Mummy Found in Hadong, Republic of Korea
    Min Seo, Dong Hoon Shin, Sang-Mee Guk, Chang Seok Oh, Eun-Joo Lee, Myung Ho Shin, Myeung Ju Kim, Soong Deok Lee, Yi-Suk Kim, Yang Su Yi, Mark Spigelman, Jong-Yil Chai
    Journal of Parasitology.2008; 94(2): 467.     CrossRef
  • A new endemic focus of Gymnophalloides seoi infection on Aphae Island, Shinan-gun, Jeollanam-do
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    The Korean Journal of Parasitology.2005; 43(4): 129.     CrossRef
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    Parasitology International.2002; 51(2): 129.     CrossRef
  • A review of Gymnophalloides seoi (Digenea: Gymnophallidae) and human infections in the Republic of Korea
    Soon-Hyung Lee, Jong-Yil Chai
    The Korean Journal of Parasitology.2001; 39(2): 85.     CrossRef
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  • 99 Download
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