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Case Report

Trichinosis Imitating an Inflammatory Systematic Disease
Maria Kosmidou, Georgios Papamichail, Eleftherios Klouras, Konstantinos Tsamis, Ioannis Sarmas, Iro Rapti, Haralampos Milionis
Korean J Parasitol 2021;59(5):497-499.
Published online October 22, 2021
DOI: https://doi.org/10.3347/kjp.2021.59.5.497
Trichinellosis (trichinosis) is a parasitic infection caused by nematodes of the genus Trichinella. Pigs are the most common source of human infection. We describe a case of a 47-year-old woman presented with a wide range of intermittent symptoms including prolonged fever, dry cough, diarrhea, rash, myalgias and arthralgias. The patient was attended by physicians with various medical specialties such as dermatologists, rheumatologists and allergiologists, but they did not establish a certain diagnosis because of the gradual onset of symptoms, raising the suspicion of a systematic disease. After extensive work up, the diagnosis of trichinosis was established with femoral muscle biopsy compatible with inflammatory myopathy of parasitic etiology with trichinosis to be the predominant diagnosis. Despite the significant delay of diagnosis for almost three months, patient was treated successfully with no further complications. Trichinellosis is a food-borne treatable infection. Preventive measures include community education especially in zones where parasite prevalence is increased, improvement of farming and cooking techniques.

Citations

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  • Immunomodulatory and anti-inflammatory effects of fluvoxamine during the intestinal phase of Trichinella spiralis infection in mice
    Wesam M. A. Elgendy, Ahmad A. Othman, Nema A. Soliman, Nivin Baiomy, Dina M. El-Guindy, Dina I. Elgendy
    Parasitology Research.2025;[Epub]     CrossRef
  • C-Reactive Protein: Pathophysiology, Diagnosis, False Test Results and a Novel Diagnostic Algorithm for Clinicians
    Dimitra S. Mouliou
    Diseases.2023; 11(4): 132.     CrossRef
  • 4,776 View
  • 98 Download
  • 2 Web of Science
  • Crossref

Original Articles

Survey of Zoonotic Trematode Metacercariae in Fish from Water Systems of Geum-gang (River) in Republic of Korea
Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Cheon-Hyeon Kim, Min-Ah Hwang, Kyeong-Woo No, Jai-Dong Kim
Korean J Parasitol 2021;59(1):23-33.
Published online February 19, 2021
DOI: https://doi.org/10.3347/kjp.2021.59.1.23
The infection status of zoonotic trematode metacercariae (ZTM) was surveyed in freshwater fishes from the water systems of Geum-gang (River) in the Republic of Korea (Korea). A total of 1,161 freshwater fishes from 6 local sites of Geum-gang were examined with the artificial digestion method for 4 years (2012-2015). Clonorchis sinensis metacercariae were detected in 122 (37.2%) out of 328 fishes in the positive fish species from 4 surveyed areas, and their mean intensity was 43 per fish infected. Metagonimus spp. metacercariae were found in 432 (51.7%) out of 835 fishes in the positive fish species from all 6 surveyed areas, and their mean intensity was 30 per fish infected. Centrocestus armatus metacercariae were detected in 285 (75.0%) out of 380 fishes in the positive fish species from 6 surveyed areas, and their mean intensity was 2,100 per fish infected. Echinostoma spp. metacercariae were found in 56 (19.7%) out of 284 fishes in the positive fish species from 5 surveyed areas, and their mean intensity was 10 per fish infected. Clinostomum complanatum metacercariae were detected in 98 (57.3%) out of 171 fishes in the positive fish species from only 2 surveyed areas, and their mean intensity was 11 per fish infected. Conclusively, the endemicity of ZTM is not so high in fishes from water systems of Geum-gang in Korea although it is more or less different by fish species, surveyed areas and ZTM species.

Citations

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  • Infection characteristics of Metagonimus species (Digenea: Heterophyidae) metacercariae in fish from major rivers of Korea
    Woon-Mok Sohn
    Parasites, Hosts and Diseases.2024; 62(1): 1.     CrossRef
  • Infection Characteristics of Clonorchis sinensis Metacercariae in Fish from Republic of Korea
    Woon-Mok Sohn
    The Korean Journal of Parasitology.2022; 60(2): 79.     CrossRef
  • Current status of Clonorchis sinensis and clonorchiasis in Korea: epidemiological perspectives integrating the data from human and intermediate hosts
    Won Gi Yoo, Woon-Mok Sohn, Byoung-Kuk Na
    Parasitology.2022; 149(10): 1296.     CrossRef
  • Prevalence and Infection Intensity of Zoonotic Trematode Metacercariae in Fish from Soyang-cheon (Stream), in Wanju-gun, Jeollabuk-do, Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Jung-Won Ju, Cheon-Hyeon Kim, Min-Ah Hwang, Kyeong-Woo No, Jong-Ho Park
    The Korean Journal of Parasitology.2021; 59(3): 265.     CrossRef
  • Survey of Zoonotic Trematode Metacercariae in Fish from Irrigation Canal of Togyo-jeosuji (Reservoir) in Cheorwon-gun, Gangwon-do, Republic of Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Hee Il Lee, Jung-Won Ju, Myoung-Ro Lee, Eun-Joo Lim, Sung Yong Son, Eunmi Ko, Jaeseok Choi
    The Korean Journal of Parasitology.2021; 59(4): 427.     CrossRef
  • 5,565 View
  • 145 Download
  • 6 Web of Science
  • Crossref
Morphological and Molecular Characteristics of Clinostomid Metacercariae from Korea and Myanmar
Eun Jeong Won, Yu Jeong Lee, Moon-Ju Kim, Jong-Yil Chai, Byoung-Kuk Na, Woon-Mok Sohn
Korean J Parasitol 2020;58(6):635-645.
Published online December 29, 2020
DOI: https://doi.org/10.3347/kjp.2020.58.6.635
Morphological and molecular characterization of clinostomid metacercariae (CMc) was performed with the specimens collected in fish from Korea and Myanmar. Total 6 batches of clinostomid specimens by the fish species and geographical localities, 5 Korean and 1 Myanmar isolates, were analyzed with morphological (light microscopy and SEM) and molecular methods (the cytochrome c oxidase 1 gene and internal transcribed spacer 1/5.8S rRNA sequence). There were some morphological variations among CMc specimens from Korea. However, some morphometrics, i.e., the size of worm body and each organ, ratio of body length to body width, and morphology of cecal lumens, were considerably different between the specimens from Korea and Myanmar. The surface ultrastructures were somewhat different between the specimens from Korea and Myanmar. The CO1 sequences of 5 Korean specimens ranging 728-736 bp showed 99.6-100% identity with Clinostomum complanatum (GenBank no. KM923964). They also showed 99.9-100% identity with C. complanatum (FJ609420) in the ITS1 sequences ranging 692-698 bp. Meanwhile, the ITS1 sequences of Myanmar specimen showed 99.9% identity with Euclinostomum heterostomum (KY312847). Five sequences from Korean specimens clustered with the C. complanatum genes, but not clustered with Myanmar specimens. Conclusively, it was confirmed that CMc from Korea were morphologically and molecularly identical with C. complanatum and those from Myanmar were E. heterostomum.

Citations

Citations to this article as recorded by  Crossref logo
  • Population structure of Clinostomum complanatum (Trematoda: Digenea) with new data on haplotype diversity of flukes from Slovakia and Italy
    Ľudmila Juhásová, Eva Čisovská Bazsalovicsová, Monica Caffara, Alžbeta Radačovská, Andrea Gustinelli, Lucia Dinisová, Yaroslav Syrota, Ivica Králová-Hromadová
    Parasite.2025; 32: 3.     CrossRef
  • Genetic variation of the freshwater snail Indoplanorbis exustus (Gastropoda: Planorbidae) in Thailand, inferred from 18S and 28S rDNA sequences
    Abdulhakam Dumidae, Chanakan Subkrasae, Jiranun Ardpairin, Supawan Pansri, Chanatinat Homkaew, Aunchalee Thanwisai, Apichat Vitta
    Parasitology Research.2024;[Epub]     CrossRef
  • Prevalence and identification of cyathocotylid trematodes infecting African catfish in Egypt
    Asmaa M. I. Abuzeid, Mahmoud M. Hefni, Amal K. El-Gayar, Yue Huang, Guoqing Li
    Parasitology Research.2024;[Epub]     CrossRef
  • Freshwater pulmonate snails and their potential role as trematode intermediate host in a cercarial dermatitis outbreak in Southern Thailand
    Thanaporn Wongpim, Jirayus Komsuwan, Chanyanuch Janmanee, Piyawan Thongchot, Sukhonta Limsampan, Nattarinee Wichiannarat, Wiyada Chaowatut, Saranphat Suwanrat, Wivitchuta Dechruksa, Nuanpan Veeravechsukij, Matthias Glaubrecht, Duangduen Krailas
    Evolutionary Systematics.2023; 7(2): 293.     CrossRef
  • Cercarial dermatitis outbreak caused by ruminant parasite with intermediate snail host: schistosome in Chana, South Thailand
    Duangduen Krailas, Suluck Namchote, Jirayus Komsuwan, Thanaporn Wongpim, Kitja Apiraksena, Matthias Glaubrecht, Pichaya Sonthiporn, Choopong Sansawang, Sirirat Suwanrit
    Evolutionary Systematics.2022; 6(2): 151.     CrossRef
  • La Presentación de Jesús en el Templo de Diego Valentín Díaz: una nueva interpretación
    Carmen De Tena Ramírez
    Archivo Español de Arte.2022; 95(378): 121.     CrossRef
  • Characterization of Clinostomum sp. (Trematoda: Clinostomidae) infecting cormorants in south-eastern Australia
    Shokoofeh Shamsi, Diane P. Barton, Scott Day, Juliet Masiga, Xiaocheng Zhu, Matthew McLellan
    Parasitology Research.2021; 120(8): 2793.     CrossRef
  • 5,238 View
  • 140 Download
  • 5 Web of Science
  • Crossref
Morphology and Molecular Identification of Echinostoma revolutum and Echinostoma macrorchis in Freshwater Snails and Experimental Hamsters in Upper Northern Thailand
Preeyaporn Butboonchoo, Chalobol Wongsawad, Pheravut Wongsawad, Jong-Yil Chai
Korean J Parasitol 2020;58(5):499-511.
Published online October 22, 2020
DOI: https://doi.org/10.3347/kjp.2020.58.5.499
Echinostome metacercariae were investigated in freshwater snails from 26 districts in 7 provinces of upper northern Thailand. The species identification was carried out based on the morphologies of the metacercariae and adult flukes harvested from experimental hamsters, and on nucleotide sequences of internal transcribed spacer 2 (ITS2) and nicotinamide adenine dinucleotide dehydrogenase subunit 1 (nad1) genes. Twenty-four out of 26 districts were found to be infected with echinostome metacercariae in freshwater snails with the prevalence of 40.4%. The metacercariae were found in all 6 species of snails, including Filopaludina martensi martensi (21.9%), Filopaludina doliaris (50.8%), F. sumatrensis polygramma (61.3%), Bithynia siamensis siamensis (14.5%), Bithynia pulchella (38.0%), and Anenthome helena (4.9%). The echinostome metacercariae found in these snails were identified as Echinostoma revolutum (37-collar-spined) and Echinostoma macrorchis (45-collar-spined) morphologically and molecularly. The 2-week-old adult flukes of E. revolutum revealed unique features of the cirrus sac extending to middle of the ventral sucker and smooth testes. E. macrorchis adults revealed the cirrus sac close to the right lateral margin of the ventral sucker and 2 large and elliptical testes with slight indentations and pointed posterior end of the posterior testis. The ITS2 and nad1 sequences confirmed the species identification of E. revolutum, and the sequences of E. macrorchis have been deposited for the first time in Gen-Bank. The presence of the life cycle of E. macrorchis is a new record in Thailand and the snail F. doliaris as their second intermediate host seems to be new among the literature.

Citations

Citations to this article as recorded by  Crossref logo
  • Filling the void: Morphological and molecular phylogenetic analyses of helminths assemblage from the Egyptian egret Bubulcus ibis
    Nada A. Ibrahim, Ismail M. Shalaby, Mahi A. Ghobashy, Azza A. Taeleb, Elham A. Elkhawass
    Parasitology International.2025; 104: 102972.     CrossRef
  • The Nuclear Ribosomal Transcription Units of Two Echinostomes and Their Taxonomic Implications for the Family Echinostomatidae
    Yu Cao, Ye Li, Zhong-Yan Gao, Bo-Tao Jiang
    Biology.2025; 14(8): 1101.     CrossRef
  • Prevalence of Foodborne Trematodes in Small Indigenous Fish Species in Local Markets of Phnom Penh, Cambodia
    Domenico Caruso, Lin Kong, Samnang Keo, Sreyni Yoeurn, Samphal Seng
    Vector-Borne and Zoonotic Diseases.2024; 24(3): 141.     CrossRef
  • Morphological and molecular characteristics of Paralecithodendrium longiforme (Digenea: Lecithodendriidae) adults and cercariae from Chinese pipistrelle bats and viviparid snails in Thailand
    Thitichai Arttra, Pheravut Wongsawad, Chalobol Wongsawad, Nattawadee Nantarat, Preeyaporn Butboonchoo, Jong-Yil Chai
    Parasites, Hosts and Diseases.2024; 62(1): 85.     CrossRef
  • Development and utilization of a visual loop-mediated isothermal amplification coupled with a lateral flow dipstick (LAMP-LFD) assay for rapid detection of Echinostomatidae metacercaria in edible snail samples
    Wasin Panich, Phonkawin Jaruboonyakorn, Awika Raksaman, Thanawan Tejangkura, Thapana Chontananarth
    International Journal of Food Microbiology.2024; 418: 110732.     CrossRef
  • Genetic diversity and population structure of the helminths intermediate host Anentome helena (von dem Busch, 1847) in northern Thailand
    Nithinan Chomchoei, Chalobol Wongsawad, Preeyaporn Butboonchoo, Nattawadee Nantarat
    Asian Pacific Journal of Tropical Medicine.2024; 17(12): 536.     CrossRef
  • Morphological and DNA analyses reveal cryptic diversity in Anentome wykoffi (Brandt, 1974) (Gastropoda: Nassariidae), with descriptions of two new species from Thailand
    Nithinan Chomchoei, Thierry Backeljau, Piyatida Pimvichai, Ting Hui Ng, Nattawadee Nantarat, Gonzalo Giribet
    Invertebrate Systematics.2023; 37(11): 755.     CrossRef
  • High diversity of trematode metacercariae that parasitize freshwater gastropods in Bangkok, Thailand, and their infective situations, morphologies and phylogenetic relationships
    Pichit Wiroonpan, Thapana Chontananarth, Jong-Yil Chai, Watchariya Purivirojkul
    Parasitology.2022; 149(7): 913.     CrossRef
  • Unwanted ‘hitchhikers’ of ornamental snails: a case report of digeneans transported via the international pet trade
    A. Stanicka, R. Maciaszek, A. Cichy, J. Templin, W. Świderek, E. Żbikowska, A. M. Labecka
    The European Zoological Journal.2022; 89(1): 601.     CrossRef
  • Morphological and molecular characterization of larval trematodes infecting the assassin snail genusAnentomein Thailand
    N. Chomchoei, T. Backeljau, B. Segers, C. Wongsawad, P. Butboonchoo, N. Nantarat
    Journal of Helminthology.2022;[Epub]     CrossRef
  • 10,091 View
  • 234 Download
  • 10 Web of Science
  • Crossref
Echinostoma mekongi n. sp. (Digenea: Echinostomatidae) from Riparian People along the Mekong River in Cambodia
Jaeeun Cho, Bong-Kwang Jung, Taehee Chang, Woon-Mok Sohn, Muth Sinuon, Jong-Yil Chai
Korean J Parasitol 2020;58(4):431-443.
Published online August 25, 2020
DOI: https://doi.org/10.3347/kjp.2020.58.4.431
Echinostoma mekongi n. sp. (Digenea: Echinostomatidae) is described based on adult flukes collected from humans residing along the Mekong River in Cambodia. Total 256 flukes were collected from the diarrheic stool of 6 echinostome egg positive villagers in Kratie and Takeo Province after praziquantel treatment and purging. Adults of the new species were 9.0-13.1 (av. 11.3) mm in length and 1.3-2.5 (1.9) mm in maximum width and characterized by having a head collar armed with 37 collar spines (dorsal spines arranged in 2 alternative rows), including 5 end group spines. The eggs in feces and worm uterus were 98-132 (117) μm long and 62-90 (75) μm wide. These morphological features closely resembled those of Echinostoma revolutum, E. miyagawai, and several other 37-collar-spined Echinostoma species. However, sequencing of the nuclear ITS (ITS1-5.8S rRNA-ITS2) and 2 mitochondrial genes, cox1 and nad1, revealed unique features distinct from E. revolutum and also from other 37-collar-spined Echinostoma group available in GenBank (E. bolschewense, E. caproni, E. cinetorchis, E. deserticum, E. miyagawai, E. nasincovae, E. novaezealandense, E. paraensei, E. paraulum, E. robustum, E. trivolvis, and Echinostoma sp. IG). Thus, we assigned our flukes as a new species, E. mekongi. The new species revealed marked variation in the morphology of testes (globular or lobulated), and smaller head collar, collar spines, oral and ventral suckers, and cirrus sac compared to E. revolutum and E. miyagawai. Epidemiological studies regarding the geographical distribution and its life history, including the source of human infections, remain to be performed.

Citations

Citations to this article as recorded by  Crossref logo
  • The Nuclear Ribosomal Transcription Units of Two Echinostomes and Their Taxonomic Implications for the Family Echinostomatidae
    Yu Cao, Ye Li, Zhong-Yan Gao, Bo-Tao Jiang
    Biology.2025; 14(8): 1101.     CrossRef
  • Prevalence of Foodborne Trematodes in Small Indigenous Fish Species in Local Markets of Phnom Penh, Cambodia
    Domenico Caruso, Lin Kong, Samnang Keo, Sreyni Yoeurn, Samphal Seng
    Vector-Borne and Zoonotic Diseases.2024; 24(3): 141.     CrossRef
  • High Prevalence of Echinostoma mekongi Infection in Schoolchildren and Adults, Kandal Province, Cambodia
    Bong-Kwang Jung, Taehee Chang, Seungwan Ryoo, Sooji Hong, Jeonggyu Lee, Sung-Jong Hong, Woon-Mok Sohn, Virak Khieu, Rekol Huy, Jong-Yil Chai
    Emerging Infectious Diseases.2024;[Epub]     CrossRef
  • Development and utilization of a visual loop-mediated isothermal amplification coupled with a lateral flow dipstick (LAMP-LFD) assay for rapid detection of Echinostomatidae metacercaria in edible snail samples
    Wasin Panich, Phonkawin Jaruboonyakorn, Awika Raksaman, Thanawan Tejangkura, Thapana Chontananarth
    International Journal of Food Microbiology.2024; 418: 110732.     CrossRef
  • First molecular insights into gastrointestinal helminths of domestic birds in the Caspian Sea Littoral of Iran with an emphasis on the One Health concern
    Aida Vafae Eslahi, Majid Pirestani, Armin Aligolzadeh, Oskar Nowak, Elham Hajialilo, Pourya Fathollahzadeh, Fahimeh Hajiaghaee, Milad Badri, Luís Manuel Madeira de Carvalho
    Veterinary Parasitology: Regional Studies and Reports.2024; 51: 101035.     CrossRef
  • Characterization of Echinostoma spp. (Trematoda: Echinostomatidae Looss, 1899) infecting ducks in south-eastern Australia
    Madeleine Ray, Michael Trinidad, Nidhish Francis, Shokoofeh Shamsi
    International Journal of Food Microbiology.2024; 421: 110754.     CrossRef
  • Genetic diversity and population structure of the helminths intermediate host Anentome helena (von dem Busch, 1847) in northern Thailand
    Nithinan Chomchoei, Chalobol Wongsawad, Preeyaporn Butboonchoo, Nattawadee Nantarat
    Asian Pacific Journal of Tropical Medicine.2024; 17(12): 536.     CrossRef
  • High endemicity of Opisthorchis viverrini infection among people in northern Cambodia confirmed by adult worm expulsion
    Bong-Kwang Jung, Sooji Hong, Taehee Chang, Jaeeun Cho, Seungwan Ryoo, Keon Hoon Lee, Jeonggyu Lee, Woon-Mok Sohn, Sung-Jong Hong, Virak Khieu, Rekol Huy, Jong-Yil Chai
    Scientific Reports.2023;[Epub]     CrossRef
  • High diversity of trematode metacercariae that parasitize freshwater gastropods in Bangkok, Thailand, and their infective situations, morphologies and phylogenetic relationships
    Pichit Wiroonpan, Thapana Chontananarth, Jong-Yil Chai, Watchariya Purivirojkul
    Parasitology.2022; 149(7): 913.     CrossRef
  • Neglected food-borne trematodiases: echinostomiasis and gastrodiscoidiasis
    Rafael Toledo, María Álvarez-Izquierdo, J. Guillermo Esteban, Carla Muñoz-Antoli
    Parasitology.2022; 149(10): 1319.     CrossRef
  • General overview of the current status of human foodborne trematodiasis
    Jong-Yil Chai, Bong-Kwang Jung
    Parasitology.2022; 149(10): 1262.     CrossRef
  • Echinostoma mekongi: Discovery of Its Metacercarial Stage in Snails, Filopaludina martensi cambodjensis, in Pursat Province, Cambodia
    Jong-Yil Chai, Woon-Mok Sohn, Jaeeun Cho, Bong-Kwang Jung, Taehee Chang, Keon Hoon Lee, Virak Khieu, Rekol Huy
    The Korean Journal of Parasitology.2021; 59(1): 47.     CrossRef
  • Echinostoma miyagawai Ishii, 1932 (Echinostomatidae) from Ducks in Aceh Province, Indonesia with Special Reference to Its Synonymy with Echinostoma robustum Yamaguti, 1935
    Jong-Yil Chai, Bong-Kwang Jung, Taehee Chang, Hyejoo Shin, Jaeeun Cho, Jin-Youp Ryu, Hyun-Seung Kim, Kwanghoon Park, Mun-Hyoo Jeong, Eui-Hyug Hoang, Marzuki Bin Muhammad Abdullah
    The Korean Journal of Parasitology.2021; 59(1): 35.     CrossRef
  • Acanthoparyphium shinanense n. sp. (Digenea: Echinostomatidae) from Experimental Chicks Infected with Metacercariae Encysted in Brackish Water Clams in the Republic of Korea
    Seungwan Ryoo, Bong-Kwang Jung, Taehee Chang, Sooji Hong, Hyejoo Shin, Jong-Yil Chai
    The Korean Journal of Parasitology.2021; 59(4): 341.     CrossRef
  • Taxonomy of Echinostoma revolutum and 37-Collar-Spined Echinostoma spp.: A Historical Review
    Jong-Yil Chai, Jaeeun Cho, Taehee Chang, Bong-Kwang Jung, Woon-Mok Sohn
    The Korean Journal of Parasitology.2020; 58(4): 343.     CrossRef
  • 7,594 View
  • 148 Download
  • 17 Web of Science
  • Crossref

Invited Review

Taxonomy of Echinostoma revolutum and 37-Collar-Spined Echinostoma spp.: A Historical Review
Jong-Yil Chai, Jaeeun Cho, Taehee Chang, Bong-Kwang Jung, Woon-Mok Sohn
Korean J Parasitol 2020;58(4):343-371.
Published online August 25, 2020
DOI: https://doi.org/10.3347/kjp.2020.58.4.343
Echinostoma flukes armed with 37 collar spines on their head collar are called as 37-collar-spined Echinostoma spp. (group) or ‘Echinostoma revolutum group’. At least 56 nominal species have been described in this group. However, many of them were morphologically close to and difficult to distinguish from the other, thus synonymized with the others. However, some of the synonymies were disagreed by other researchers, and taxonomic debates have been continued. Fortunately, recent development of molecular techniques, in particular, sequencing of the mitochondrial (nad1 and cox1) and nuclear genes (ITS region; ITS1-5.8S-ITS2), has enabled us to obtain highly useful data on phylogenetic relationships of these 37-collar-spined Echinostoma spp. Thus, 16 different species are currently acknowledged to be valid worldwide, which include E. revolutum, E. bolschewense, E. caproni, E. cinetorchis, E. deserticum, E. lindoense, E. luisreyi, E. mekongi, E. miyagawai, E. nasincovae, E. novaezealandense, E. paraensei, E. paraulum, E. robustum, E. trivolvis, and Echinostoma sp. IG of Georgieva et al., 2013. The validity of the other 10 species is retained until further evaluation, including molecular analyses; E. acuticauda, E. barbosai, E. chloephagae, E. echinatum, E. jurini, E. nudicaudatum, E. parvocirrus, E. pinnicaudatum, E. ralli, and E. rodriguesi. In this review, the history of discovery and taxonomic debates on these 26 valid or validity-retained species are briefly reviewed.

Citations

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  • Development of a duplex loop-mediated isothermal amplification together with lateral flow dipstick assay for the detection and discrimination of parasitic infections in chickens between cestodes belonging to genus Raillietina and trematodes in family Echi
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    Research in Veterinary Science.2025; 185: 105539.     CrossRef
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  • Development and utilization of a visual loop-mediated isothermal amplification coupled with a lateral flow dipstick (LAMP-LFD) assay for rapid detection of Echinostomatidae metacercaria in edible snail samples
    Wasin Panich, Phonkawin Jaruboonyakorn, Awika Raksaman, Thanawan Tejangkura, Thapana Chontananarth
    International Journal of Food Microbiology.2024; 418: 110732.     CrossRef
  • First molecular insights into gastrointestinal helminths of domestic birds in the Caspian Sea Littoral of Iran with an emphasis on the One Health concern
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    Marisa C. Valadão, Philippe V. Alves, Danimar López-Hernández, Jordana C. A. Assis, Paulo R. S. Coelho, Stefan M. Geiger, Hudson A. Pinto
    Parasitology.2023; 150(4): 337.     CrossRef
  • A new species ofEchinostoma(Trematoda: Echinostomatidae) from the ‘revolutum’ group found in Brazil: refuting the occurrence ofEchinostoma miyagawai(=E. robustum) in the Americas
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  • High diversity of trematode metacercariae that parasitize freshwater gastropods in Bangkok, Thailand, and their infective situations, morphologies and phylogenetic relationships
    Pichit Wiroonpan, Thapana Chontananarth, Jong-Yil Chai, Watchariya Purivirojkul
    Parasitology.2022; 149(7): 913.     CrossRef
  • Neglected food-borne trematodiases: echinostomiasis and gastrodiscoidiasis
    Rafael Toledo, María Álvarez-Izquierdo, J. Guillermo Esteban, Carla Muñoz-Antoli
    Parasitology.2022; 149(10): 1319.     CrossRef
  • General overview of the current status of human foodborne trematodiasis
    Jong-Yil Chai, Bong-Kwang Jung
    Parasitology.2022; 149(10): 1262.     CrossRef
  • Morphological and molecular characterization of larval trematodes infecting the assassin snail genusAnentomein Thailand
    N. Chomchoei, T. Backeljau, B. Segers, C. Wongsawad, P. Butboonchoo, N. Nantarat
    Journal of Helminthology.2022;[Epub]     CrossRef
  • Echinostoma miyagawai Ishii, 1932 (Echinostomatidae) from Ducks in Aceh Province, Indonesia with Special Reference to Its Synonymy with Echinostoma robustum Yamaguti, 1935
    Jong-Yil Chai, Bong-Kwang Jung, Taehee Chang, Hyejoo Shin, Jaeeun Cho, Jin-Youp Ryu, Hyun-Seung Kim, Kwanghoon Park, Mun-Hyoo Jeong, Eui-Hyug Hoang, Marzuki Bin Muhammad Abdullah
    The Korean Journal of Parasitology.2021; 59(1): 35.     CrossRef
  • Echinostoma mekongi: Discovery of Its Metacercarial Stage in Snails, Filopaludina martensi cambodjensis, in Pursat Province, Cambodia
    Jong-Yil Chai, Woon-Mok Sohn, Jaeeun Cho, Bong-Kwang Jung, Taehee Chang, Keon Hoon Lee, Virak Khieu, Rekol Huy
    The Korean Journal of Parasitology.2021; 59(1): 47.     CrossRef
  • On the Helminth Fauna of the Muskrat (Ondatra zibethicus (Linnaeus, 1766)) in the Barnim District of Brandenburg State/Germany
    Rolf K. Schuster, Peter Specht, Siegfried Rieger
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  • Echinostoma mekongi n. sp. (Digenea: Echinostomatidae) from Riparian People along the Mekong River in Cambodia
    Jaeeun Cho, Bong-Kwang Jung, Taehee Chang, Woon-Mok Sohn, Muth Sinuon, Jong-Yil Chai
    The Korean Journal of Parasitology.2020; 58(4): 431.     CrossRef
  • 9,497 View
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Brief Communications

Echinostoma aegyptica (Trematoda: Echinostomatidae) Infection in Five Riparian People in Savannakhet Province, Lao PDR
Jong-Yil Chai, Bong-Kwang Jung, Taehee Chang, Hyejoo Shin, Woon-Mok Sohn, Keeseon S. Eom, Tai-Soon Yong, Duk-Young Min, Bounlay Phammasack, Bounnaloth Insisiengmay, Han-Jong Rim
Korean J Parasitol 2020;58(1):67-72.
Published online February 29, 2020
DOI: https://doi.org/10.3347/kjp.2020.58.1.67
Human infection with Echinostoma aegyptica Khalil and Abaza, 1924 (Trematoda: Echinostomatidae) is extremely rare. In this study, we confirmed E. aegyptica infection in 5 riparian residents living along the Mekong River in Savannakhet Province, Lao PDR. The patients revealed eggs of Opisthorchis viverrini/minute intestinal flukes, echinostomes, and other parasites in fecal examinations using the Kato-Katz technique. Following treatment with praziquantel 30-40 mg/kg and pyrantel pamoate 10-15 mg/kg in a single dose and purging with magnesium salts, adult specimens of various helminth species were collected. Among the trematodes, echinostome flukes of 4.5-7.6 mm in length (n = 134; av. 22.3 specimens per case) were of taxonomic interest and subjected in this study. The flukes were morphologically characterized by having total 43-45 collar spines arranged in 2 alternating rows (corner spines usually 5 on each side) and compatible with previous descriptions of E. aegyptica. The patients were mixed-infected with other helminths, so specific clinical manifestations due to this echinostome fluke were difficult to determine. The present paper describes for the first time human E. aegyptica infections in Lao PDR. This is the second report of human infection (2nd-6th cases) with E. aegyptica in the world following the first one from China.

Citations

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  • High endemicity of Opisthorchis viverrini infection among people in northern Cambodia confirmed by adult worm expulsion
    Bong-Kwang Jung, Sooji Hong, Taehee Chang, Jaeeun Cho, Seungwan Ryoo, Keon Hoon Lee, Jeonggyu Lee, Woon-Mok Sohn, Sung-Jong Hong, Virak Khieu, Rekol Huy, Jong-Yil Chai
    Scientific Reports.2023;[Epub]     CrossRef
  • Neglected food-borne trematodiases: echinostomiasis and gastrodiscoidiasis
    Rafael Toledo, María Álvarez-Izquierdo, J. Guillermo Esteban, Carla Muñoz-Antoli
    Parasitology.2022; 149(10): 1319.     CrossRef
  • Echinostoma mekongi n. sp. (Digenea: Echinostomatidae) from Riparian People along the Mekong River in Cambodia
    Jaeeun Cho, Bong-Kwang Jung, Taehee Chang, Woon-Mok Sohn, Muth Sinuon, Jong-Yil Chai
    The Korean Journal of Parasitology.2020; 58(4): 431.     CrossRef
  • 8,105 View
  • 122 Download
  • 5 Web of Science
  • Crossref
Echinochasmus caninus n. comb. (Trematoda: Echinostomatidae) Infection in Eleven Riparian People in Khammouane Province, Lao PDR
Jong-Yil Chai, Taehee Chang, Bong-Kwang Jung, Hyejoo Shin, Woon-Mok Sohn, Keeseon S. Eom, Tai-Soon Yong, Duk-Young Min, Bounlay Phammasack, Bounnaloth Insisiengmay, Han-Jong Rim
Korean J Parasitol 2019;57(4):451-456.
Published online August 31, 2019
DOI: https://doi.org/10.3347/kjp.2019.57.4.451
Adult specimens of Echinochasmus caninus n. comb. (Verma, 1935) (Trematoda: Echinostomatidae) (syn. Episthmium caninum Yamaguti, 1958) were recovered from 11 riparian people who resided along the Mekong River in Khammouane Province, Lao PDR. In fecal examinations done by the Kato-Katz technique, the cases revealed eggs of Opisthorchis viverrini/minute intestinal flukes, hookworms, and in 2 cases echinostome eggs. To recover the adult helminths, praziquantel 30-40 mg/kg and pyrantel pamoate 10-15 mg/kg in a single dose were given and purged with magnesium salts. Various species of trematodes (including O. viverrini and Haplorchis spp.), cestodes, and nematodes were recovered from their diarrheic stools. Among the trematodes, small echinostome flukes (n=42; av. 3.8 specimens per case) of 0.7-1.2 mm in length are subjected in this study. They are morphologically characterized by having 24 collar spines interrupted dorsally and anterior extension of vitellaria from the cirrus sac or genital pore level to the posterior end of the body. Particularly based on this extensive distribution of vitellaria, the specific diagnosis was made as Echinochasmus caninus. The cases were co-infected with various other helminth parasites; thus, clinical manifestations specific for this echinostome infection were difficult to determine. The present paper describes for the first time human E. caninus infections in Lao PDR. Our cases marked the 4-14th human infections with this echinostome around the world following the 3 previous cases reported from Thailand.

Citations

Citations to this article as recorded by  Crossref logo
  • Neglected food-borne trematodiases: echinostomiasis and gastrodiscoidiasis
    Rafael Toledo, María Álvarez-Izquierdo, J. Guillermo Esteban, Carla Muñoz-Antoli
    Parasitology.2022; 149(10): 1319.     CrossRef
  • General overview of the current status of human foodborne trematodiasis
    Jong-Yil Chai, Bong-Kwang Jung
    Parasitology.2022; 149(10): 1262.     CrossRef
  • Echinostoma aegyptica (Trematoda: Echinostomatidae) Infection in Five Riparian People in Savannakhet Province, Lao PDR
    Jong-Yil Chai, Bong-Kwang Jung, Taehee Chang, Hyejoo Shin, Woon-Mok Sohn, Keeseon S. Eom, Tai-Soon Yong, Duk-Young Min, Bounlay Phammasack, Bounnaloth Insisiengmay, Han-Jong Rim
    The Korean Journal of Parasitology.2020; 58(1): 67.     CrossRef
  • Echinostoma mekongi n. sp. (Digenea: Echinostomatidae) from Riparian People along the Mekong River in Cambodia
    Jaeeun Cho, Bong-Kwang Jung, Taehee Chang, Woon-Mok Sohn, Muth Sinuon, Jong-Yil Chai
    The Korean Journal of Parasitology.2020; 58(4): 431.     CrossRef
  • Echinostoma macrorchis Metacercariae in Cipangopaludina chinensis malleata from Xiengkhuang Province, Lao PDR and Morphologies of Adults from Experimental Animals
    Woon-Mok Sohn, Byoung-Kuk Na, Dongmin Lee, Keeseon S. Eom, Tai-Soon Yong, Jong-Yil Chai, Duk-Young Min
    The Korean Journal of Parasitology.2019; 57(6): 657.     CrossRef
  • 8,223 View
  • 155 Download
  • 7 Web of Science
  • Crossref
Echinostoma ilocanum Infection in Two Residents of Savannakhet Province, Lao PDR
Jong-Yil Chai, Woon-Mok Sohn, Jaeeun Cho, Keeseon S. Eom, Tai-Soon Yong, Duk-Young Min, Eui-Hyug Hoang, Bounlay Phommasack, Bounnaloth Insisiengmay, Han-Jong Rim
Korean J Parasitol 2018;56(1):75-79.
Published online February 28, 2018
DOI: https://doi.org/10.3347/kjp.2018.56.1.75
Adult specimens of Echinostoma ilocanum (Garrison, 1908) Odhner, 1911 (Trematoda: Echinostomatidae) were recovered from 2 riparian people who resided along the Mekong River in Savannakhet Province, Lao PDR. In fecal examinations done by the Kato-Katz technique, they revealed echinostome eggs together with eggs of Opisthorchis viverrini (and minute intestinal fluke eggs) and hookworms. To recover the adult flukes, they were treated with praziquantel 30-40 mg/kg in a single dose and purged with magnesium salts. A total of 658 adult fluke specimens were recovered from the 2 people; 456 from case 1 and 202 from case 2. Specimens from case 1 consisted of 335 echinostomes (301 E. ilocanum and 34 species undetermined), 120 O. viverrini, and 1 Haplorchis taichui, and those from case 2 consisted of 36 E. ilocanum, 134 O. viverrini, and 32 H. taichui. Thus, the number of E. ilocanum specimens was 337 in total (average per person, 168.5). From this study, it is suggested that foodborne intestinal flukes and liver flukes are highly prevalent along the Mekong River in Savannakhet Province. The present report describes for the first time human infections with E. ilocanum in Lao PDR.

Citations

Citations to this article as recorded by  Crossref logo
  • Development and utilization of a visual loop-mediated isothermal amplification coupled with a lateral flow dipstick (LAMP-LFD) assay for rapid detection of Echinostomatidae metacercaria in edible snail samples
    Wasin Panich, Phonkawin Jaruboonyakorn, Awika Raksaman, Thanawan Tejangkura, Thapana Chontananarth
    International Journal of Food Microbiology.2024; 418: 110732.     CrossRef
  • Neglected food-borne trematodiases: echinostomiasis and gastrodiscoidiasis
    Rafael Toledo, María Álvarez-Izquierdo, J. Guillermo Esteban, Carla Muñoz-Antoli
    Parasitology.2022; 149(10): 1319.     CrossRef
  • General overview of the current status of human foodborne trematodiasis
    Jong-Yil Chai, Bong-Kwang Jung
    Parasitology.2022; 149(10): 1262.     CrossRef
  • Foodborne intestinal flukes: A brief review of epidemiology and geographical distribution
    Jong-Yil Chai, Bong-Kwang Jung
    Acta Tropica.2020; 201: 105210.     CrossRef
  • Echinostoma aegyptica (Trematoda: Echinostomatidae) Infection in Five Riparian People in Savannakhet Province, Lao PDR
    Jong-Yil Chai, Bong-Kwang Jung, Taehee Chang, Hyejoo Shin, Woon-Mok Sohn, Keeseon S. Eom, Tai-Soon Yong, Duk-Young Min, Bounlay Phammasack, Bounnaloth Insisiengmay, Han-Jong Rim
    The Korean Journal of Parasitology.2020; 58(1): 67.     CrossRef
  • Echinostoma mekongi n. sp. (Digenea: Echinostomatidae) from Riparian People along the Mekong River in Cambodia
    Jaeeun Cho, Bong-Kwang Jung, Taehee Chang, Woon-Mok Sohn, Muth Sinuon, Jong-Yil Chai
    The Korean Journal of Parasitology.2020; 58(4): 431.     CrossRef
  • Echinochasmus caninus n. comb. (Trematoda: Echinostomatidae) Infection in Eleven Riparian People in Khammouane Province, Lao PDR
    Jong-Yil Chai, Taehee Chang, Bong-Kwang Jung, Hyejoo Shin, Woon-Mok Sohn, Keeseon S. Eom, Tai-Soon Yong, Duk-Young Min, Bounlay Phammasack, Bounnaloth Insisiengmay, Han-Jong Rim
    The Korean Journal of Parasitology.2019; 57(4): 451.     CrossRef
  • 10,243 View
  • 177 Download
  • 11 Web of Science
  • Crossref
Artyfechinostomum malayanum: Metacercariae Encysted in Pila sp. Snails Purchased from Phnom Penh, Cambodia
Woon-Mok Sohn, Tai-Soon Yong, Keeseon S. Eom, Muth Sinuon, Hoo-Gn Jeoung, Jong-Yil Chai
Korean J Parasitol 2017;55(3):341-345.
Published online June 30, 2017
DOI: https://doi.org/10.3347/kjp.2017.55.3.341
The metacercariae of Artyfechinostomum malayanum (Leiper, 1911) Mendheim, 1943 were discovered in Pila sp. snails purchased from a market in Phnom Penh, Cambodia. They were isolated from the snails using the artificial digestion technique and were orally fed to 2 hamsters, 1 rat, and 2 mice to obtain the adult flukes. The metacercariae were round, 145-165 μm in diameter, having a cyst wall of 6-10 μm in thickness, a head collar and collar spines, and characteristic features of excretory granules. Adult flukes were recovered in the small intestines of the animals at days 14 and 32 post infection and were morphologically observed using a light microscope and a scanning electron microscope. They were plump or elongated, ventrally curved, 6.0-8.1×1.6-2.0 mm in size, and characterized by the head collar bearing 43 collar spines, including 5 end group ones on each side, a long cirrus sac extending beyond the posterior margin of the ventral sucker, a submedian ovary, and 2 deeply lobed testes. Eggs in uteri were operculate, ovoid to ellipsoid, and 120-135×68-75 μm in size. In scanning electron microscopy, the head collar was prominent with collar spines looking like horns. Scale-like tegumental spines were densely distributed on the ventral surface between the head collar and ventral sucker. Sensory papillae were distributed mainly on the tegument around suckers. By this study, it has been first confirmed that the life cycle of A. malayanum exists in Cambodia.

Citations

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  • The ribosomal transcription units of five echinostomes and their taxonomic implications for the suborder Echinostomata (Trematoda: Platyhelminthes)
    Thanh Hoa Le, Linh Thi Khanh Pham, Dong Van Quyen, Khue Thi Nguyen, Huong Thi Thanh Doan, Weerachai Saijuntha, David Blair
    Parasitology Research.2024;[Epub]     CrossRef
  • Biological Hazards and Indicators Found in Products of Animal Origin in Cambodia from 2000 to 2022: A Systematic Review
    Shwe Phue San, Rortana Chea, Delia Grace, Kristina Roesel, Sothyra Tum, Stephen Young, Tumnoon Charaslertrangsi, Nazanin Zand, Shetty Seetharama Thombathu, Ra Thorng, Leab Kong, Kuok Fidero, Linda Nicolaides
    International Journal of Environmental Research and Public Health.2024; 21(12): 1621.     CrossRef
  • Mitophylogenomics of the zoonotic fluke Echinostoma malayanum confirms it as a member of the genus Artyfechinostomum Lane, 1915 and illustrates the complexity of Echinostomatidae systematics
    Linh Thi Khanh Pham, Weerachai Saijuntha, Scott P. Lawton, Thanh Hoa Le
    Parasitology Research.2022; 121(3): 899.     CrossRef
  • High diversity of trematode metacercariae that parasitize freshwater gastropods in Bangkok, Thailand, and their infective situations, morphologies and phylogenetic relationships
    Pichit Wiroonpan, Thapana Chontananarth, Jong-Yil Chai, Watchariya Purivirojkul
    Parasitology.2022; 149(7): 913.     CrossRef
  • General overview of the current status of human foodborne trematodiasis
    Jong-Yil Chai, Bong-Kwang Jung
    Parasitology.2022; 149(10): 1262.     CrossRef
  • Foodborne intestinal flukes: A brief review of epidemiology and geographical distribution
    Jong-Yil Chai, Bong-Kwang Jung
    Acta Tropica.2020; 201: 105210.     CrossRef
  • 11,005 View
  • 153 Download
  • 7 Web of Science
  • Crossref

Original Articles

Two Echinostome Species, Pegosomum bubulcum and Nephrostomum ramosum (Digenea: Echinostomatidae), from an Eastern Cattle Egret, Bubulcus ibis coromandus, in Republic of Korea
Seongjun Choe, Dongmin Lee, Hansol Park, Hyeong-Kyu Jeon, Youngsun Lee, Eunju Kim, Ki-Jeong Na, Keeseon S. Eom
Korean J Parasitol 2016;54(4):485-496.
Published online August 31, 2016
DOI: https://doi.org/10.3347/kjp.2016.54.4.485
We describe 2 echinostome species recovered from an Eastern cattle egret, Bubulcus ibis coromandus, from Cheongju-si (city), Chungcheongbuk-do (province), Korea. Total 72 Pegosomum bubulcum specimens were recovered from the bile duct. They were 7,566×2,938 μm in average size and had 27 collar spines with vitelline extension from anterior 1/3 level of the esophagus to mid-level of the posterior testis as characteristic features. Total 9 specimens of Nephrostomum ramosum were recovered in the small intestines of the bird. They were ribbon-shaped, 11,378×2,124 μm in average size, and morphologically variable in some organs, i.e., the number of collar spines (47-50), the shape of ovary and testes, and the extension of vitelline follicles. These morphological variations observed in a single host indicated that these features are not critical for the classification of Nephrostomum species and thus were reconsidered taxonomically as synonym of N. ramosum. This study is the first report documenting and describing both flukes and their associated genera in Korea.

Citations

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  • Filling the void: Morphological and molecular phylogenetic analyses of helminths assemblage from the Egyptian egret Bubulcus ibis
    Nada A. Ibrahim, Ismail M. Shalaby, Mahi A. Ghobashy, Azza A. Taeleb, Elham A. Elkhawass
    Parasitology International.2025; 104: 102972.     CrossRef
  • 18S rRNA gene metabarcoding for investigation of gastrointestinal parasite diversity in great cormorants
    Subin Lee, Badriah Alkathiri, Chang Hyeon Lee, Heon Woo Lee, Dong-Hyuk Jeong, Ju Yeong Kim, Seongjun Choe, Seung-Hun Lee
    Scientific Reports.2025;[Epub]     CrossRef
  • Molecular and morphological support for the synonymy of Nephrostomum and Patagifer: discovery of new species and broad geographic connections
    María G. Díaz González, Danimar López-Hernández, Vasyl V. Tkach, Fabiana Drago, Fred D. Chibwana, Martina R. Laidemitt, Christopher A. Blanar, Verónica Núñez, Mariano Dueñas Díaz, Luis A. Gomez-Puerta, Sean A. Locke
    International Journal for Parasitology.2025;[Epub]     CrossRef
  • Infections with Digenetic Trematode Metacercariae in Freshwater Fishes from Two Visiting Sites of Migratory Birds in Gyeongsangnam-do, Republic of Korea
    Woon-Mok Sohn, Byoung-Kuk Na
    The Korean Journal of Parasitology.2019; 57(3): 273.     CrossRef
  • Infections of Two Isthmiophora Species (Digenea: Echinostomatidae) in Wild Mammals from Republic of Korea with Their Morphological Descriptions
    Seongjun Choe, Ki-Jeong Na, Youngjun Kim, Dong-Hyuk Jeong, Jeong-Jin Yang, Keeseon S. Eom
    The Korean Journal of Parasitology.2019; 57(6): 647.     CrossRef
  • New Definitive Hosts and Differential Body Indices of Isthmiophora hortensis (Digenea: Echinostomatidae)
    Woon-Mok Sohn, Byoung-Kuk Na, Sung-Shik Shin
    The Korean Journal of Parasitology.2017; 55(3): 287.     CrossRef
  • Echinostoma macrorchis (Digenea: Echinostomatidae): Metacercariae in Cipangopaludina chinensis malleata Snails and Adults from Experimental Rats in Korea
    Woon-Mok Sohn, Byoung-Kuk Na
    The Korean Journal of Parasitology.2017; 55(5): 541.     CrossRef
  • 11,097 View
  • 225 Download
  • 6 Web of Science
  • Crossref
Complete Mitochondrial Genome of Echinostoma hortense (Digenea: Echinostomatidae)
Ze-Xuan Liu, Yan Zhang, Yu-Ting Liu, Qiao-Cheng Chang, Xin Su, Xue Fu, Dong-Mei Yue, Yuan Gao, Chun-Ren Wang
Korean J Parasitol 2016;54(2):173-179.
Published online April 30, 2016
DOI: https://doi.org/10.3347/kjp.2016.54.2.173
Echinostoma hortense (Digenea: Echinostomatidae) is one of the intestinal flukes with medical importance in humans. However, the mitochondrial (mt) genome of this fluke has not been known yet. The present study has determined the complete mt genome sequences of E. hortense and assessed the phylogenetic relationships with other digenean species for which the complete mt genome sequences are available in GenBank using concatenated amino acid sequences inferred from 12 protein-coding genes. The mt genome of E. hortense contained 12 protein-coding genes, 22 transfer RNA genes, 2 ribosomal RNA genes, and 1 non-coding region. The length of the mt genome of E. hortense was 14,994 bp, which was somewhat smaller than those of other trematode species. Phylogenetic analyses based on concatenated nucleotide sequence datasets for all 12 protein-coding genes using maximum parsimony (MP) method showed that E. hortense and Hypoderaeum conoideum gathered together, and they were closer to each other than to Fasciolidae and other echinostomatid trematodes. The availability of the complete mt genome sequences of E. hortense provides important genetic markers for diagnostics, population genetics, and evolutionary studies of digeneans.

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  • Genetic variation and population structure of Haemonchus contortus: an in-silico analysis
    W. Wei, Z. Lan, Xuewei Liu, Xinhui Zhang, X. Gu, R. Wang
    Journal of Helminthology.2025;[Epub]     CrossRef
  • The Nuclear Ribosomal Transcription Units of Two Echinostomes and Their Taxonomic Implications for the Family Echinostomatidae
    Yu Cao, Ye Li, Zhong-Yan Gao, Bo-Tao Jiang
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  • The complete mitochondrial genome of Aspidogaster ijimai (Platyhelminthes: Trematoda: Aspidogastrea): gene content and phylogenetic inference
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    Invertebrate Zoology.2025; 22(3): 411.     CrossRef
  • Complete mitochondrial genome and phylogenetic analysis of Dollfustrema vaneyi (Trematoda: Bucephalidae)
    Ye Hu, Tong Ye, Hong Zou, Gui-Tang Wang, Wen-Xiang Li, Dong Zhang
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  • Characterization of the complete mitochondrial genome of Plagiorchis multiglandularis (Digenea, Plagiorchiidae): Comparison with the members of Xiphidiatan species and phylogenetic implications
    Janelle Laura J. Gacad, Natalia I. Yurlova, Natalia M. Ponomareva, Misako Urabe
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  • A report on the complete mitochondrial genome of the trematode Azygia robusta Odhner, 1911, its new definitive host from the Russian Far East, and unexpected phylogeny of Azygiidae within Digenea, as inferred from mitogenome sequences
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    Xin-ru Guo, Ye Li, Yuan Gao, Yang-yuan Qiu, Zhen-hua Jin, Zhong-yan Gao, Xian-guang Zhang, Qi An, Qiao-cheng Chang, Jun-feng Gao, Chun-ren Wang
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    Y.I. Ivashko, A.A. Semenchenko, D.A. Solodovnik, D.M. Atopkin
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  • First next-generation sequencing data for Haploporidae (Digenea: Haploporata): characterization of complete mitochondrial genome and ribosomal operon for Parasaccocoelium mugili Zhukov, 1971
    Dmitry M. Atopkin, Alexander A. Semenchenko, Daria A. Solodovnik, Yana I. Ivashko, Kirill A. Vinnikov
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  • Characterization of the complete mitochondrial genome sequence of Tracheophilus cymbius (Digenea), the first representative from the family Cyclocoelidae
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  • Mitochondrial Genome Sequence of Echinostoma revolutum from Red-Crowned Crane (Grus japonensis)
    Rongkun Ran, Qi Zhao, Asmaa M. I. Abuzeid, Yue Huang, Yunqiu Liu, Yongxiang Sun, Long He, Xiu Li, Jumei Liu, Guoqing Li
    The Korean Journal of Parasitology.2020; 58(1): 73.     CrossRef
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    Yuan-An Wu, Jin-Wei Gao, Xiao-Fei Cheng, Min Xie, Xi-Ping Yuan, Dong Liu, Rui Song
    ZooKeys.2020; 945: 1.     CrossRef
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    Toby Landeryou, Stephen M. Kett, Anne Ropiquet, Dirk Wildeboer, Scott P. Lawton
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    Suleman, Jun Ma, Mian Sayed Khan, Vasyl V. Tkach, Nehaz Muhammad, Dong Zhang, Xing-Quan Zhu
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    Jun Ma, Jun-Jun He, Cheng-Yan Zhou, Miao-Miao Sun, William Cevallos, Hiromu Sugiyama, Xing-Quan Zhu, Manuel Calvopiña
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    Suleman, Mian Sayed Khan, Petr Heneberg, Cheng-Yan Zhou, Nehaz Muhammad, Xing-Quan Zhu, Jun Ma
    Parasitology Research.2019; 118(7): 2203.     CrossRef
  • The complete mitochondrial genome of Echinostoma miyagawai: Comparisons with closely related species and phylogenetic implications
    Ye Li, Yang-Yuan Qiu, Min-Hao Zeng, Pei-Wen Diao, Qiao-Cheng Chang, Yuan Gao, Yan Zhang, Chun-Ren Wang
    Infection, Genetics and Evolution.2019; 75: 103961.     CrossRef
  • Mitochondrial DNA Evidence Supports the Hypothesis that Triodontophorus Species Belong to Cyathostominae
    Yuan Gao, Yan Zhang, Xin Yang, Jian-Hua Qiu, Hong Duan, Wen-Wen Xu, Qiao-Cheng Chang, Chun-Ren Wang
    Frontiers in Microbiology.2017;[Epub]     CrossRef
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Animal Models for Echinostoma malayanum Infection: Worm Recovery and Some Pathology
Jiraporn Songsri, Ratchadawan Aukkanimart, Thidarut Boonmars, Panaratana Ratanasuwan, Porntip Laummaunwai, Pranee Sriraj, Panupan Sripan
Korean J Parasitol 2016;54(1):47-53.
Published online February 26, 2016
DOI: https://doi.org/10.3347/kjp.2016.54.1.47
Echinostomes are intestinal trematodes that infect a wide range of vertebrate hosts, including humans, in their adult stage and also parasitize numerous invertebrate and cold-blooded vertebrate hosts in their larval stages. The purpose of this study was to compare Echinostoma malayanum parasite growth, including worm recovery, body size of adult worms, eggs per worm, eggs per gram of feces, and pathological changes in the small intestine of experimental animals. In this study, 6-8-week-old male hamsters, rats, mice, and gerbils were infected with echinostome metacercariae and then sacrificed at day 60 post-infection. The small intestine and feces of each infected animal were collected and then processed for analysis. The results showed that worm recovery, eggs per worm, and eggs per gram of feces from all infected hamsters were higher compared with infected rats and mice. However, in infected gerbils, no parasites were observed in the small intestine, and there were no parasite eggs in the feces. The volume of eggs per gram of feces and eggs per worm were related to parasite size. The results of histopathological changes in the small intestine of infected groups showed abnormal villi and goblet cells, as evidenced by short villi and an increase in the number and size of goblet cells compared with the normal control group.

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  • Research Note: Genetic analysis, pathology, and vectors of echinostomiasis, a zoonotic helminth infection in chickens in Bangladesh
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    Poultry Science.2022; 101(3): 101682.     CrossRef
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    Jian Li, Yijing Ren, Lei Yang, Jiani Guo, Haiying Chen, Jiani Liu, Haoqiang Tian, Qingan Zhou, Weiyi Huang, Wei Hu, Xinyu Feng
    Infectious Diseases of Poverty.2022;[Epub]     CrossRef
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    Asmaa M. I. Abuzeid, Mahmoud M. Hefni, Yue Huang, Long He, Tingting Zhuang, Guoqing Li
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    Dimple Mandla, Neena Singla, Sukhmanpreet Kaur Brar, Lachhman Das Singla
    Biologia.2022; 78(1): 119.     CrossRef
  • Artyfechinostomum malayanum: Metacercariae Encysted in Pila sp. Snails Purchased from Phnom Penh, Cambodia
    Woon-Mok Sohn, Tai-Soon Yong, Keeseon S. Eom, Muth Sinuon, Hoo-Gn Jeoung, Jong-Yil Chai
    The Korean Journal of Parasitology.2017; 55(3): 341.     CrossRef
  • 28,407 View
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Trematode Metacercariae in Freshwater Fish from Water Systems of Hantangang and Imjingang in Republic of Korea
Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Soon-Won Lee, Seung-Bong Choi, Won-Seok Seok
Korean J Parasitol 2015;53(3):289-298.
Published online June 30, 2015
DOI: https://doi.org/10.3347/kjp.2015.53.3.289
The infection status of freshwater fish with digenetic trematode metacercariae was examined in water systems of Hantangang and Imjingang (River), the Republic of Korea. A total of 877 (594 from Hantangang and 283 from Imjingang) fishes were examined by the artificial digestion methods. Clonorchis sinensis metacercariae were detected in 7 (1.2%) fishes (in 3 spp.) from Hantangang in Cheorwon-gun, Gangwon-do, and 40 (14.1%) fishes (in 7 spp.) from Munsancheon in Paju-si, Gyeonggi-do. The average densities were 1.9 and 35.6 per fish infected, respectively. Metagonimus spp. metacercariae were detected in 312 (52.5%) and 113 (39.9%) fishes from Hantangang and Imjingang, and their average densities were 47.5 and 9.6 per fish infected, respectively. Centrocestus armatus metacercariae were found in 161 (27.1%) and 70 (24.7%) fishes from Hantangang and Imjingang, and their average number per fish infected was 694 and 82, respectively. Echinostoma spp. metacercariae were detected in 50 (8.4%) and 94 (33.2%) fishes from Hantangang and Imjingang, and their average densities were 9.6 and 23.1 per fish infected, respectively. The infection status of fishes with metacercariae of Stephanoprora spp., Diplostomum spp., Clinostomum complanatum, Metorchis orientalis, and Metorchis taiwanensis were analyzed by surveyed regions. Conclusively, it was confirmed that C. sinensis metacercariae were quite commonly detected in fishes from Munsancheon but rarely from other localities, whereas the metacercariae of other digenetic trematodes were relatively prevalent in fishes from water systems of Hantangang and Imjingang in Korea.

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    Domenico Caruso, Lin Kong, Samnang Keo, Sreyni Yoeurn, Samphal Seng
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  • Infection characteristics of Metagonimus species (Digenea: Heterophyidae) metacercariae in fish from major rivers of Korea
    Woon-Mok Sohn
    Parasites, Hosts and Diseases.2024; 62(1): 1.     CrossRef
  • Re‐evaluation of certain aspects of the EFSA Scientific Opinion of April 2010 on risk assessment of parasites in fishery products, based on new scientific data. Part 2
    Ana Allende, Avelino Alvarez‐Ordóñez, Valeria Bortolaia, Sara Bover‐Cid, Alessandra De Cesare, Wietske Dohmen, Laurent Guillier, Lieve Herman, Liesbeth Jacxsens, Maarten Nauta, Lapo Mughini‐Gras, Jakob Ottoson, Luisa Peixe, Fernando Perez‐Rodriguez, Panag
    EFSA Journal.2024;[Epub]     CrossRef
  • Infection Characteristics of Clonorchis sinensis Metacercariae in Fish from Republic of Korea
    Woon-Mok Sohn
    The Korean Journal of Parasitology.2022; 60(2): 79.     CrossRef
  • Current status of Clonorchis sinensis and clonorchiasis in Korea: epidemiological perspectives integrating the data from human and intermediate hosts
    Won Gi Yoo, Woon-Mok Sohn, Byoung-Kuk Na
    Parasitology.2022; 149(10): 1296.     CrossRef
  • Survey of Zoonotic Trematode Metacercariae in Fish from Water Systems of Geum-gang (River) in Republic of Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Cheon-Hyeon Kim, Min-Ah Hwang, Kyeong-Woo No, Jai-Dong Kim
    The Korean Journal of Parasitology.2021; 59(1): 23.     CrossRef
  • Prevalence and Infection Intensity of Zoonotic Trematode Metacercariae in Fish from Soyang-cheon (Stream), in Wanju-gun, Jeollabuk-do, Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Jung-Won Ju, Cheon-Hyeon Kim, Min-Ah Hwang, Kyeong-Woo No, Jong-Ho Park
    The Korean Journal of Parasitology.2021; 59(3): 265.     CrossRef
  • Survey of Zoonotic Trematode Metacercariae in Fish from Irrigation Canal of Togyo-jeosuji (Reservoir) in Cheorwon-gun, Gangwon-do, Republic of Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Hee Il Lee, Jung-Won Ju, Myoung-Ro Lee, Eun-Joo Lim, Sung Yong Son, Eunmi Ko, Jaeseok Choi
    The Korean Journal of Parasitology.2021; 59(4): 427.     CrossRef
  • Endemicity of Zoonotic Trematode Metacercariae in Fish from Deokcheon-gang (River) in Sancheong-gun, Gyeongsangnam-do, Republic of Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Hee Il Lee, Jung-Won Ju, Myoung-Ro Lee, Jeong-Gil Park, Jihee Ahn
    The Korean Journal of Parasitology.2021; 59(5): 523.     CrossRef
  • Intestinal Flukes Recovered from a Herring Gull, Larus argentatus, in the Republic of Korea
    Young-Il Lee, Min Seo, Jong-Yil Chai
    The Korean Journal of Parasitology.2020; 58(1): 81.     CrossRef
  • Diagnosis of Centrocestus formosanus Infection in Zebrafish (Danio rerio) in Italy: A Window to a New Globalization-Derived Invasive Microorganism
    Antonino Pace, Ludovico Dipineto, Serena Aceto, Maria Concetta Censullo, Maria Carmen Valoroso, Lorena Varriale, Laura Rinaldi, Lucia Francesca Menna, Alessandro Fioretti, Luca Borrelli
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  • Morphological and Molecular Characteristics of Clinostomid Metacercariae from Korea and Myanmar
    Eun Jeong Won, Yu Jeong Lee, Moon-Ju Kim, Jong-Yil Chai, Byoung-Kuk Na, Woon-Mok Sohn
    The Korean Journal of Parasitology.2020; 58(6): 635.     CrossRef
  • Infection Status with Clonorchis sinensis Metacercariae in Fish from Yangcheon (Stream) in Sancheong-gun, Gyeongsangnam-do, Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Jung-Won Ju
    The Korean Journal of Parasitology.2019; 57(2): 145.     CrossRef
  • Infections with Digenetic Trematode Metacercariae in Freshwater Fishes from Two Visiting Sites of Migratory Birds in Gyeongsangnam-do, Republic of Korea
    Woon-Mok Sohn, Byoung-Kuk Na
    The Korean Journal of Parasitology.2019; 57(3): 273.     CrossRef
  • Infection Status with Clinostomum complanatum Metacercariae in Fish from Water Systems of Nakdong-gang (River) in Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho
    The Korean Journal of Parasitology.2019; 57(4): 389.     CrossRef
  • Infection Status with Digenetic Trematode Metacercariae in Fishes from Coastal Lakes in Gangwon-do, Republic of Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Soon-Won Lee
    The Korean Journal of Parasitology.2019; 57(6): 681.     CrossRef
  • Prevalence and Intensity of Clonorchis sinensis Metacercariae in Freshwater Fish from Wicheon Stream in Gunwi-gun, Gyeongsangbuk-do, Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Jung-Won Ju, Dong-Chul Son
    The Korean Journal of Parasitology.2018; 56(1): 41.     CrossRef
  • Infection Status with Clonorchis sinensis Metacercariae in Fish from Tamjin-gang (River) in Jeollanam-do, Republic of Korea
    Ki-Bok Yoon, Hyun-Cheol Lim, Doo Young Jeon, Sook Park, Shin-Hyeong Cho, Jung-Won Ju, Sung-Shik Shin, Byoung-Kuk Na, Woon-Mok Sohn
    The Korean Journal of Parasitology.2018; 56(2): 183.     CrossRef
  • Infections with Centrocestus armatus Metacercariae in Fishes from Water Systems of Major Rivers in Republic of Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Jung-Won Ju, Cheon-Hyeon Kim, Ki-Bok Yoon, Jai-Dong Kim, Dong Cheol Son, Soon-Won Lee
    The Korean Journal of Parasitology.2018; 56(4): 341.     CrossRef
  • Infection Status with Metagonimus spp. Metacercariae in Fishes from Seomjin-gang and Tamjin-gang in Republic of Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Jung-Won Ju, Cheon-Hyeon Kim, Ki-Bok Yoon
    The Korean Journal of Parasitology.2018; 56(4): 351.     CrossRef
  • Infections with Digenean Trematode Metacercariae in Two Invasive Alien Fish, Micropterus salmoides and Lepomis macrochirus, in Two Rivers in Chungcheongbuk-do, Republic of Korea
    Seongjun Choe, Hansol Park, Dongmin Lee, Yeseul Kang, Hyeong-Kyu Jeon, Keeseon S. Eom
    The Korean Journal of Parasitology.2018; 56(5): 509.     CrossRef
  • A Case of Endoscopically Treated Laryngopharyngitis Resulting fromClinostomum complanatumInfection
    Geum Soo Lee, Sang Wook Park, Jin Kim, Kang Seok Seo, Kyoung Wan You, Jae Hun Chung, Hyeong Chul Moon, Gun Young Hong
    The Korean Journal of Gastroenterology.2017; 69(3): 177.     CrossRef
  • Prevalence of Clonorchis sinensis Metacercariae in Fish from Water Systems of Seomjin-gang (River)
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Mi-Yeoun Park, Cheon-Hyeon Kim, Min-Ah Hwang, Kyeong-Woo No, Ki-Bok Yoon, Hyun-Cheol Lim
    The Korean Journal of Parasitology.2017; 55(3): 305.     CrossRef
  • X-ray microcomputed tomography reveals putative trematode metacercaria in a 100 million year-old lizard (Squamata: Agamidae)
    George Poinar, Kenneth A. Philbrick, Martin J. Cohn, Russell T. Turner, Urszula T. Iwaniec, Joerg Wunderlich
    Cretaceous Research.2017; 80: 27.     CrossRef
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Three Echinostome Species from Wild Birds in the Republic of Korea
Seongjun Choe, Dongmin Lee, Hansol Park, Mihyeon Oh, Hyeong-Kyu Jeon, Youngsun Lee, Ki-Jeong Na, Youngjun Kim, Hang Lee, Keeseon S. Eom
Korean J Parasitol 2014;52(5):513-520.
Published online October 22, 2014
DOI: https://doi.org/10.3347/kjp.2014.52.5.513

Three echinostome species, i.e., Patagifer bilobus, Petasiger neocomense, and Saakotrema metatestis, are newly recorded in the trematode fauna of the Republic of Korea. They were recovered from 3 species of migratory birds (Platalea minor, Podiceps cristatus, and Egretta garzetta), which were donated by the Wildlife Center of Chungbuk (WCC) and the Conservation Genome Resource Bank for Korean Wildlife (CGRB). Only 1 P. bilobus specimen was recovered from the intestine of a black-faced spoonbill (P. minor), and characterized by the bilobed head crown with a deep dorsal incision and 54 collar spines. Twenty P. neocomense were recovered from the intestine of a great crested grebe (P. cristatus), and they had a well-developed head crown with 19 spines and 2 testes obliquely located at the posterior middle of the body. Total 70 S. metatestis were collected from the bursa of Fabricius of 1 little egret (E. garzetta). It is characterized by stout tegumental spines covered in the entire leaf-shaped body, posterior extension of the uterus, presence of the uroproct and a well-developed head crown with 12 pairs of collar spines on each side. By the present study, these 3 echinostome species are newly added to the trematode fauna in Korea.

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  • Filling the void: Morphological and molecular phylogenetic analyses of helminths assemblage from the Egyptian egret Bubulcus ibis
    Nada A. Ibrahim, Ismail M. Shalaby, Mahi A. Ghobashy, Azza A. Taeleb, Elham A. Elkhawass
    Parasitology International.2025; 104: 102972.     CrossRef
  • The Nuclear Ribosomal Transcription Units of Two Echinostomes and Their Taxonomic Implications for the Family Echinostomatidae
    Yu Cao, Ye Li, Zhong-Yan Gao, Bo-Tao Jiang
    Biology.2025; 14(8): 1101.     CrossRef
  • First record of Patagifer bilobus (Rudolphi, 1819) Dietz, 1909 (Digenea: Echinostomatidae), with a morphological and molecular characterization from two threskiornithid species in Mexico
    Ana Lucia Sereno-Uribe, Marcelo Tonatiuh González-García, Mirza Patricia Ortega-Olivares, Alejandra López-Jiménez, Martín García-Varela, Leopoldo Andrade-Gómez
    Parasitology Research.2022; 121(7): 1921.     CrossRef
  • EXAMINATION OF HELMINTH PARASITES IN THE FECAL SAMPLES OF MAGPIES (Pica pica), JACKDAWS (Corvus monedula), AND ROOKS (Corvus frugilegus) IN THE VICINITIES OF VAN PROVINCE/TURKEY
    Ali Bilgin YILMAZ, Erkan AZİZOĞLU, Özdemir ADIZEL
    Commagene Journal of Biology.2020;[Epub]     CrossRef
  • Infections with Digenetic Trematode Metacercariae in Freshwater Fishes from Two Visiting Sites of Migratory Birds in Gyeongsangnam-do, Republic of Korea
    Woon-Mok Sohn, Byoung-Kuk Na
    The Korean Journal of Parasitology.2019; 57(3): 273.     CrossRef
  • Infections of Two Isthmiophora Species (Digenea: Echinostomatidae) in Wild Mammals from Republic of Korea with Their Morphological Descriptions
    Seongjun Choe, Ki-Jeong Na, Youngjun Kim, Dong-Hyuk Jeong, Jeong-Jin Yang, Keeseon S. Eom
    The Korean Journal of Parasitology.2019; 57(6): 647.     CrossRef
  • Echinochasmus swabiensis n. sp. (Digenea: Echinostomatidae) from Black Kite (Milvus Migrans Migrans) in Swabi District, Pakistan
    S. Suleman, M. S. Khan, X. Q. Zhu, A. M. Dharejo, E. C. Uwalaka, M. Shah, O. A. Adediran
    Folia Veterinaria.2018; 62(2): 5.     CrossRef
  • New Definitive Hosts and Differential Body Indices of Isthmiophora hortensis (Digenea: Echinostomatidae)
    Woon-Mok Sohn, Byoung-Kuk Na, Sung-Shik Shin
    The Korean Journal of Parasitology.2017; 55(3): 287.     CrossRef
  • Echinostoma macrorchis (Digenea: Echinostomatidae): Metacercariae in Cipangopaludina chinensis malleata Snails and Adults from Experimental Rats in Korea
    Woon-Mok Sohn, Byoung-Kuk Na
    The Korean Journal of Parasitology.2017; 55(5): 541.     CrossRef
  • Two Echinostome Species, Pegosomum bubulcum and Nephrostomum ramosum (Digenea: Echinostomatidae), from an Eastern Cattle Egret, Bubulcus ibis coromandus, in Republic of Korea
    Seongjun Choe, Dongmin Lee, Hansol Park, Hyeong-Kyu Jeon, Youngsun Lee, Eunju Kim, Ki-Jeong Na, Keeseon S. Eom
    The Korean Journal of Parasitology.2016; 54(4): 485.     CrossRef
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Amoebic PI3K and PKC Is Required for Jurkat T Cell Death Induced by Entamoeba histolytica
Young Ah Lee, Kyeong Ah Kim, Arim Min, Myeong Heon Shin
Korean J Parasitol 2014;52(4):355-365.
Published online August 29, 2014
DOI: https://doi.org/10.3347/kjp.2014.52.4.355

The enteric protozoan parasite Entamoeba histolytica is the causative agent of human amebiasis. During infection, adherence of E. histolytica through Gal/GalNAc lectin on the surface of the amoeba can induce caspase-3-dependent or -independent host cell death. Phosphorylinositol 3-kinase (PI3K) and protein kinase C (PKC) in E. histolytica play an important function in the adhesion, killing, or phagocytosis of target cells. In this study, we examined the role of amoebic PI3K and PKC in amoeba-induced apoptotic cell death in Jurkat T cells. When Jurkat T cells were incubated with E. histolytica trophozoites, phosphatidylserine (PS) externalization and DNA fragmentation in Jurkat cells were markedly increased compared to those of cells incubated with medium alone. However, when amoebae were pretreated with a PI3K inhibitor, wortmannin before being incubated with E. histolytica, E. histolytica-induced PS externalization and DNA fragmentation in Jurkat cells were significantly reduced compared to results for amoebae pretreated with DMSO. In addition, pretreatment of amoebae with a PKC inhibitor, staurosporine strongly inhibited Jurkat T cell death. However, E. histolytica-induced cleavage of caspase-3, -6, and -7 were not inhibited by pretreatment of amoebae with wortmannin or staurosporin. In addition, we found that amoebic PI3K and PKC have an important role on amoeba adhesion to host compartment. These results suggest that amebic PI3K and PKC activation may play an important role in caspase-independent cell death in Entamoeba-induced apoptosis.

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    Nancy Guillén
    Virulence.2023;[Epub]     CrossRef
  • Apoptotic mimicry as a strategy for the establishment of parasitic infections: parasite- and host-derived phosphatidylserine as key molecule
    João Luiz Mendes Wanderley, Renato Augusto DaMatta, Marcello André Barcinski
    Cell Communication and Signaling.2020;[Epub]     CrossRef
  • Entamoeba histolytica Up-Regulates MicroRNA-643 to Promote Apoptosis by Targeting XIAP in Human Epithelial Colon Cells
    Itzel López-Rosas, César López-Camarillo, Yarely M. Salinas-Vera, Olga N. Hernández-de la Cruz, Carlos Palma-Flores, Bibiana Chávez-Munguía, Osbaldo Resendis-Antonio, Nancy Guillen, Carlos Pérez-Plasencia, María Elizbeth Álvarez-Sánchez, Esther Ramírez-Mo
    Frontiers in Cellular and Infection Microbiology.2019;[Epub]     CrossRef
  • Phosphatidylinositol Kinases and Phosphatases in Entamoeba histolytica
    Kumiko Nakada-Tsukui, Natsuki Watanabe, Tomohiko Maehama, Tomoyoshi Nozaki
    Frontiers in Cellular and Infection Microbiology.2019;[Epub]     CrossRef
  • AGC family kinase 1 participates in trogocytosis but not in phagocytosis in Entamoeba histolytica
    Somlata, Kumiko Nakada-Tsukui, Tomoyoshi Nozaki
    Nature Communications.2017;[Epub]     CrossRef
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  • 9 Web of Science
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Case Report

A Case of Echinostoma cinetorchis (Trematoda: Echinostomatidae) Infection Diagnosed by Colonoscopy
Woon Tae Jung, Kyeong Ju Lee, Hong Jun Kim, Tae Hyo Kim, Byoung-Kuk Na, Woon-Mok Sohn
Korean J Parasitol 2014;52(3):287-290.
Published online June 26, 2014
DOI: https://doi.org/10.3347/kjp.2014.52.3.287

Human cases of echinostomiasis have been sporadically diagnosed by extracting worms in the endoscopy in Korea and Japan. Most of these were caused by Echinostoma hortense infection. However, in the present study, we detected 2 live worms of Echinostoma cinetorchis in the ascending colon of a Korean man (68-year old) admitted to the Gyeongsang National University Hospital with complaint of intermittent right lower quadrant abdominal pain for 5 days. Under colonoscopy, 1 worm was found attached on the edematous and hyperemic mucosal surface of the proximal ascending colon and the other was detected on the mid-ascending colon. Both worms were removed from the mucosal surface with a grasping forceps, and morphologically identified as E. cinetorchis by the characteristic head crown with total 37 collar spines including 5 end-group ones on both sides, disappearance of testes, and eggs of 108×60 ?m with abopercular wrinkles. The infection source of this case seems to be the raw frogs eaten 2 months ago. This is the first case of endoscopy-diagnosed E. cinetorchis infection in Korea.

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Original Articles

A Cross-Sectional Study on Intestinal Parasitic Infections in Rural Communities, Northeast Thailand
Sirintip Boonjaraspinyo, Thidarut Boonmars, Butsara Kaewsamut, Nuttapon Ekobol, Porntip Laummaunwai, Ratchadawan Aukkanimart, Nadchanan Wonkchalee, Amornrat Juasook, Pranee Sriraj
Korean J Parasitol 2013;51(6):727-734.
Published online December 31, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.6.727

Despite the existence of effective anthelmintics, parasitic infections remain a major public health problem in Southeast Asia, including Thailand. In rural communities, continuing infection is often reinforced by dietary habits that have a strong cultural basis and by poor personal hygiene and sanitation. This study presents a survey of the prevalence of intestinal parasitic infections among the people in rural Thailand. The community-based cross-sectional study was conducted in villages in Khon Kaen Province, northeastern Thailand, from March to August 2013. A total of 253 stool samples from 102 males and 140 females, aged 2-80 years, were prepared using formalin-ethyl acetate concentration methods and examined using light microscopy. Ninety-four individuals (37.2%) were infected with 1 or more parasite species. Presence of parasitic infection was significantly correlated with gender (P=0.001); nearly half of males in this survey (49.0%) were infected. Older people had a higher prevalence than younger members of the population. The most common parasite found was Opisthorchis viverrini (26.9%), followed by Strongyloides stercoralis (9.5%), Taenia spp. (1.6%), echinostomes (0.4%), and hookworms (0.4%). The prevalence of intestinal protozoa was Blastocystis hominis 1.6%, Entamoeba histolytica 0.8%, Entamoeba coli 0.8%, Balantidium coli 0.4%, Iodamoeba b?tschlii 0.4%, and Sarcocystis hominis 0.4%. Co-infections of various helminths and protozoa were present in 15.9% of the people. The present results show that the prevalence of parasitic infections in this region is still high. Proactive education about dietary habits, personal hygiene, and sanitation should be provided to the people in this community to reduce the prevalence of intestinal parasite infections. Moreover, development of policies and programs to control parasites is needed.

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Zoonotic Echinostome Infections in Free-Grazing Ducks in Thailand
Weerachai Saijuntha, Kunyarat Duenngai, Chairat Tantrawatpan
Korean J Parasitol 2013;51(6):663-667.
Published online December 31, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.6.663

Free-grazing ducks play a major role in the rural economy of Eastern Asia in the form of egg and meat production. In Thailand, the geographical location, tropical climate conditions and wetland areas of the country are suitable for their husbandry. These environmental factors also favor growth, multiplication, development, survival, and spread of duck parasites. In this study, a total of 90 free-grazing ducks from northern, central, and northeastern regions of Thailand were examined for intestinal helminth parasites, with special emphasis on zoonotic echinostomes. Of these, 51 (56.7%) were infected by one or more species of zoonotic echinostomes, Echinostoma revolutum, Echinoparyphium recurvatum, and Hypoderaeum conoideum. Echinostomes found were identified using morphological criteria when possible. ITS2 sequences were used to identify juvenile and incomplete worms. The prevalence of infection was relatively high in each region, namely, north, central, and northeast region was 63.2%, 54.5%, and 55.3%, respectively. The intensity of infection ranged up to 49 worms/infected duck. Free-grazing ducks clearly play an important role in the life cycle maintenance, spread, and transmission of these medically important echinostomes in Thailand.

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Morphological and Molecular Characterization of Lymnaeid Snails and Their Potential Role in Transmission of Fasciola spp. in Vietnam
Bui Thi Dung, Pham Ngoc Doanh, Dang Tat The, Ho Thi Loan, Bertrand Losson, Yannick Caron
Korean J Parasitol 2013;51(6):657-662.
Published online December 31, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.6.657

Freshwater snails of the family Lymnaeidae play an important role in the transmission of fascioliasis worldwide. In Vietnam, 2 common lymnaeid species, Lymnaea swinhoei and Lymnaea viridis, can be recognized on the basis of morphology, and a third species, Lymnaea sp., is known to exist. Recent studies have raised controversy about their role in transmission of Fasciola spp. because of confusion in identification of the snail hosts. The aim of this study is, therefore, to clarify the identities of lymnaeid snails in Vietnam by a combination of morphological and molecular approaches. The molecular analyses using the second internal transcribed spacer (ITS2) of the nuclear ribosomal DNA clearly showed that lymnaeids in Vietnam include 3 species, Austropeplea viridis (morphologically identified as L. viridis), Radix auricularia (morphologically identified as L. swinhoei) and Radix rubiginosa (morphologically identified as Lymnaea sp.). R. rubiginosa is a new record for Vietnam. Among them, only A. viridis was found to be infected with Fasciola spp. These results provide a new insight into lymnaeid snails in Vietnam. Identification of lymnaeid snails in Vietnam and their role in the liver fluke transmission should be further investigated.

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Brief Communication

Intestinal Parasites among Wild Rodents in Northern Gangwon-do, Korea
Young-Il Lee, Hee-Jang Pyeon, Min Seo
Korean J Parasitol 2013;51(5):603-606.
Published online October 31, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.5.603

To determine geographical patterns of natural parasite infections among wild rodents, a total of 46 wild rodents from 3 different localities in northern Gangwon-do (Province), Korea were examined for intestinal parasite infections. Along with nematodes such as hookworms and Syphacia spp., Plagiorchis muris (2 specimens) (Trematoda) were collected from striped field mice, Apodemus agrarius. In a Korean wood mouse, Apodemus peninsulae, the overall nematode infections were similar to A. agrarius, but an adult worm of Echinostoma hortense (Trematoda) was collected. In addition, 2 species of cestodes, i.e., Hymenolepis nana and Hymenolepis diminuta, were collected from A. agrarius. Through this survey, A. agrarius and A. peninsule were confirmed as the natural definite hosts for zoonotic intestinal helminths, i.e., P. muris, E. hortense, H. nana, and H. diminuta, in northern Gangwon-do, Korea. Considering increased leisure activities around these areas, seasonal and further comprehensive surveys on wild rodents seem to be needed to prevent zoonotic parasite infections.

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    Biologia.2022; 78(1): 119.     CrossRef
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    Parasites & Vectors.2022;[Epub]     CrossRef
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    Jae-Hyung Lee, Shuang Gong, Yung Chul Park, Hyun-Ju Kim, In-Wook Choi, Young-Ha Lee
    The Korean Journal of Parasitology.2018; 56(3): 301.     CrossRef
  • Study of Internal Parasites of Rodents in Ahvaz, South-West of Iran
    Mahmoud Rahdar, Elham-Al- Sadat Roointan, Babak Vazirianzadeh, Alireza Alborzi
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    The Korean Journal of Parasitology.2014; 52(4): 419.     CrossRef
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Case Report

Trichinosis Caused by Ingestion of Raw Soft-Shelled Turtle Meat in Korea
Sang-Rok Lee, Sang-Hoon Yoo, Hyun-Seon Kim, Seung-Ha Lee, Min Seo
Korean J Parasitol 2013;51(2):219-221.
Published online April 25, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.2.219

Reptiles, unlike mammals, have been considered to be unsuitable hosts of Trichinella spp., though larvae have been detected in their muscles and human outbreaks related to their consumption have, in fact, occurred. Herein we report 2 Korean cases of trichinosis, possibly transmitted via consumption of reptile meat. Both patients suffered from myalgia, headache, and facial edema. Laboratory examinations revealed leukocytosis with eosinophilia (54% and 39%, respectively) and elevated creatinine phosphokinase. ELISA was performed under the suspicion of trichinosis, showing positivity at the 29th and 60th day post-infection. Since they had consumed raw soft-shelled turtle meat, turtle was strongly suggested to be an infection source of trichinosis in Korea next to the wild boar and badger.

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    Aquaculture Reports.2024; 37: 102227.     CrossRef
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    Parasitology.2017; 144(6): 793.     CrossRef
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    Parasitology International.2013; 62(6): 583.     CrossRef
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Original Articles

Echinostoma macrorchis in Lao PDR: Metacercariae in Cipangopaludina Snails and Adults from Experimentally Infected Animals
Woon-Mok Sohn, Jong-Yil Chai, Byoung-Kuk Na, Tai-Soon Yong, Keeseon S. Eom, Hansol Park, Duk-Young Min, Han-Jong Rim
Korean J Parasitol 2013;51(2):191-196.
Published online April 25, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.2.191

The echinostome metacercariae encysted in Cipangopaludina sp. snails that were purchased from a market in Vientiane Municipality, Lao PDR, were identified as Echinostoma macrorchis (Digenea: Echinostomatidae) through recovery of adult flukes after experimental infection to rats and a cat. The metacercariae were round, 113-128 (121)×113-125 (120) ?m, having a thick cyst wall, a head collar armed with collar spines, and excretory granules. The adult flukes recovered from the rats and cat at day 14 and 30 post-infection, respectively, were elongated, ventrally curved, and 3.9-6.3×0.7-1.1 mm in size. The head collar was distinct, bearing 43-45 collar spines with 5 angle spines on each side. Two testes were large (as the name implies), tandem, and slightly constricted at the middle, with irregular margins. Eggs were operculated, ovoid to elliptical, and 88-95×56-60 ?m. In scanning electron microscopy, the head collar was prominent, with 43-45 collar spines. Scale-like tegumental spines were densely distributed on the ventral surface between the oral and ventral suckers. Sensory papillae were distributed mainly on the tegument around the 2 suckers. It is confirmed that E. macrorchis is distributed in Lao PDR using Cipangopaludina sp. snails as the second intermediate host.

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Echinostoma revolutum: Freshwater Snails as the Second Intermediate Hosts in Chiang Mai, Thailand
Kittichai Chantima, Jong-Yil Chai, Chalobol Wongsawad
Korean J Parasitol 2013;51(2):183-189.
Published online April 25, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.2.183

The occurrence of 37-collar spined echinostome metacercariae in freshwater snails was investigated in 6 districts of Chiang Mai Province, Thailand, from October 2011 to April 2012. A total of 2,914 snails that belong to 12 species were examined, and 7 snail species (Clea helena, Eyriesia eyriesi, Bithynia funiculata, Bithynia siamensis siamensis, Filopaludina doliaris, Filopaludina sumatrensis polygramma, and Filopaludina martensi martensi) were found infected with echinostome metacercariae. The prevalence of metacercariae was the highest in Filopaludina spp. (38.5-58.7%) followed by B. funiculata (44.0%), E. eyriesi (12.5%), B. siamensis siamensis (8.2%), and C. helena (5.1%). Metacercariae were experimentally fed to hamsters and domestic chicks, and adult flukes were recovered from both hosts at days 15 and 20 post-infection. The adult flukes were identified based on morphological features, morphometrics, host-parasite relationships, and geographical distribution. They were compatible to Echinostoma revolutum or Echinostoma jurini, with only minor differences. As the adults were recovered from both hamsters and chicks, our specimens were more compatible to E. revolutum rather than E. jurini (reported only from mammals). This is the first report for metacercariae of E. revolutum in the snail host, C. helena, and also confirmed that Filopaludina spp., E. eryresi, and Bithynia spp. act as the second intermediate hosts of E. revolutum under natural conditions, which are indigenously distributed in Chiang Mai province.

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Brief Communications

Echinostome Flukes Receovered from Humans in Khammouane Province, Lao PDR
Jong-Yil Chai, Woon-Mok Sohn, Tai-Soon Yong, Keeseon S. Eom, Duk-Young Min, Eui-Hyug Hoang, Bounlay Phammasack, Bounnaloth Insisiengmay, Han-Jong Rim
Korean J Parasitol 2012;50(3):269-272.
Published online August 13, 2012
DOI: https://doi.org/10.3347/kjp.2012.50.3.269

Echinostome eggs were detected in 22 (1.1%) of 2,074 people residing in riparian villages along the Mekong River in Khammouane Province, Lao PDR. In order to recover the adult flukes, 9 persons were treated with praziquantel and purged with magnesium salts. A total of 55 echinostome specimens (4 species) were recovered from the 9 persons. Echinostoma revolutum (8 specimens) was recovered from 3 persons, Artyfechinostomum malayanum (8 specimens) was from 2 persons, Echinochasmus japonicus (33 specimens) was from 7 persons, and Euparyphium sp. (6 specimens) was from 1 person. In Lao PDR, only human infections with E. japonicus were previously known. Therefore, the present study describes human infections with E. revolutum, A. malayanum, and Euparyphium sp. for the first time in Lao PDR. These results indicate that the surveyed villages of Khammouane Province, Lao PDR are low-grade endemic foci of echinostomiasis.

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Echinostoma revolutum: Metacercariae in Filopaludina Snails from Nam Dinh Province, Vietnam, and Adults from Experimental Hamsters
Jong-Yil Chai, Woon-Mok Sohn, Byoung-Kuk Na, Nguyen Van De
Korean J Parasitol 2011;49(4):449-455.
Published online December 16, 2011
DOI: https://doi.org/10.3347/kjp.2011.49.4.449

We detected metacercariae of Echinostoma revolutum in Filopaludina sp. snails purchased from a local market in Nam Dinh Province for the first time in Vietnam. Adult flukes were harvested from experimentally infected hamsters at days 14 and 17 post-infection. The metacercariae were round, 170-190 ?m (n=15) in diameter, with a cyst wall thickness of about 12 ?m. A total of 37 collar spines were arranged around the head collar, and large excretory granules were seen in 2 canals of the excretory bladder. The 14-day old adult flukes were elongated, ventrally curved, and 5.0-7.2×0.8-1.3 mm (n=20). The head collar had a total of 37 collar spines arranged in 2 alternating rows, including 5 corner spines on each side. The cirrus sac contained a saccular seminal vesicle, a prostatic gland, and an unarmed cirrus. Two tandem testes were smooth or slightly lobed. Eggs were ovoid to elliptical, 110-118×70-75 ?m. These morphological characters were similar to those of E. revolutum and E. jurini. We tentatively identified it as E. revolutum because the validity of E. jurini remains to be elucidated. The taxonomic relationship of E. revolutum and E. jurini is discussed.

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Case Report

The Fifth Outbreak of Trichinosis in Korea
Ji-Young Rhee, Sung-Tae Hong, Hye-Jung Lee, Min Seo, Suk-Bae Kim
Korean J Parasitol 2011;49(4):405-408.
Published online December 16, 2011
DOI: https://doi.org/10.3347/kjp.2011.49.4.405

Trichinosis is a food-borne zoonotic disease caused by the nematode, Trichinella spp., and had been reported several times in Korea. Recently, there was an additional outbreak, involving 5 patients, the findings from which are reported herein. On 30 November 2010, 8 persons ate sashimi of the meat of a wild boar. Then, 2-3 weeks later, they complained of myalgia and fever. Unfortunately, muscle biopsy was not performed, but ELISA was performed using their sera. Two people among 8 were positive for Trichinella on the 34th day post-infection (PI), and 3 patients who initially revealed negative ELISA were additionally proved to be positive for trichinosis on the 42nd day PI. Hence, the confirmed patients of trichinosis were 5 in total in the present outbreak. They were treated with albendazole and discharged uneventfully. This was the fifth outbreak of trichinosis in Korea.

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    Manasawee Tanariyakul, Jonathan Estaris, Sakditad Saowapa
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    H.J. Kim, W.S. Jeong, E.M. Kim, S.G. Yeo, D.J. An, H. Yoon, E.J. Kim, C.K. Park
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    Seung Ho Bang, Jae Bum Park, Hyun Keun Chee, Jun Seok Kim, Sung Min Ko, Wan Seop Kim, Je Kyoun Shin
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Brief Communication

Echinostoma ilocanum Infection in Oddar Meanchey Province, Cambodia
Woon-Mok Sohn, Hyeong-Jin Kim, Tai-Soon Yong, Keeseon S. Eom, Hoo-Gn Jeong, Jae-Kwang Kim, A-Reum Kang, Mok-Ryun Kim, Jung-Mi Park, Soo-Hyeon Ji, Muth Sinuon, Duong Socheat, Jong-Yil Chai
Korean J Parasitol 2011;49(2):187-190.
Published online June 14, 2011
DOI: https://doi.org/10.3347/kjp.2011.49.2.187

Fecal examinations using the Kato Katz technique were performed on a total of 1,287 villagers (945 students and 342 general inhabitants) of Oddar Meanchey Province, Cambodia in May 2007 and November 2009. The overall intestinal helminth egg positive rate was 23.9%, and the most prevalent helminth species was hookworms (21.6%). Other helminth eggs detected included echinostomes (1.0%), Enterobius vermicularis (0.8%), small trematode eggs (0.7%), which may include Opisthorchis viverrini and Haplorchis spp., and Hymenolepis nana (0.4%). In order to recover adult echinostomes, we treated 2 patients with 10-15 mg/kg praziquantel and purged. Total 14 adult echinostomes, 1 and 13 worms from each patient, were collected. The echinostomes characteristically had 49-51 collar spines and 2 round or slightly lobated testes. They were identified as Echinostoma ilocanum (Garrison, 1908) Odhner, 1911. So far as literature are concerned, this is the first record on the discovery of human E. ilocanum infection in Cambodia.

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    Bong-Kwang Jung, Taehee Chang, Seungwan Ryoo, Sooji Hong, Jeonggyu Lee, Sung-Jong Hong, Woon-Mok Sohn, Virak Khieu, Rekol Huy, Jong-Yil Chai
    Emerging Infectious Diseases.2024;[Epub]     CrossRef
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    International Journal of Food Microbiology.2024; 418: 110732.     CrossRef
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    The Korean Journal of Parasitology.2017; 55(3): 341.     CrossRef
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Original Article

Enzymatic Activities of Allergen Extracts from Three Species of Dust Mites and Cockroaches Commonly Found in Korean Home
Kyoung Yong Jeong, Chungryul Kim, Tai-Soon Yong
Korean J Parasitol 2010;48(2):151-155.
Published online June 17, 2010
DOI: https://doi.org/10.3347/kjp.2010.48.2.151

Allergen extracts from dust mites and cockroaches commonly found in Korean homes were used to evaluate their enzymatic activity as they are believed to influence allergenicity. Allergen extracts were prepared from 3 dust mite species (Dermatophagoides farinae, D. pteronyssinus, and Tyrophagus putrescentiae) and 3 cockroach species (Blattella germanica, Periplaneta americana, and P. fuliginosa) maintained in the Korea National Arthropods of Medical Importance Resource Bank. Proteins were extracted in PBS after homogenization using liquid nitrogen. The activities of various enzymes were investigated using the API Zym system. No significant difference in phosphatase, lipase, or glycosidase activity was observed among the 6 allergen extracts, but much difference was observed in protease activity. Protease activity was assessed in more detail by gelatin zymography and the EnzChek assay. Extract from T. putrescentiae showed the highest protease activity, followed by those of the cockroach extracts. Extracts from D. farinae and D. pteronyssinus showed only weak protease activity. Gelatinolytic activity was detected mainly in a 30-kDa protein in D. farinae, a 28-kDa protein in D. pteronyssinus, a > 26-kDa protein in T. putrescentiae, a > 20-kDa protein in B. germanica, and a > 23-kDa protein in P. americana and P. fuliginosa. The information on various enzymatic activities obtained in this study may be useful for future studies. In particular, the strong protease activity found in cockroach extracts could contribute to sensitization to cockroach allergens, which is known to be associated with the development of asthma.

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  • B-cell antibody class switchings are pressuromodulated events: Part II, gene recombination
    Hemant Sarin
    Translational Medicine Communications.2018;[Epub]     CrossRef
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    Kyoung Yong Jeong, Mina Son, Jae-Hyun Lee, Chein-Soo Hong, Jung-Won Park
    Allergy, Asthma & Immunology Research.2015; 7(3): 283.     CrossRef
  • Current Status of Standardization of Inhalant Allergen Extracts in Korea
    Kyoung Yong Jeong, Jae-Hyun Lee, Eun-Jin Kim, Joo-Shil Lee, Sang-Heon Cho, Soo-Jong Hong, Jung-Won Park
    Allergy, Asthma & Immunology Research.2014; 6(3): 196.     CrossRef
  • Preparation and Characterization of an Extract of German Cockroach From a Korean Source
    Kyoung Yong Jeong, Soo-Young Choi, Jae-Hyun Lee, Joo-Shil Lee, Tai-Soon Yong, Chein-Soo Hong, Jung-Won Park
    Allergy, Asthma & Immunology Research.2013; 5(2): 102.     CrossRef
  • The Effects of Storage Conditions on the Stability of House Dust Mite Extracts
    Kyoung Yong Jeong, Soo-Young Choi, In-Soo Han, Jae-Hyun Lee, Joo-Shil Lee, Chein-Soo Hong, Jung-Won Park
    Allergy, Asthma & Immunology Research.2013; 5(6): 397.     CrossRef
  • House Dust Mite Allergy in Korea: The Most Important Inhalant Allergen in Current and Future
    Kyoung Yong Jeong, Jung-Won Park, Chein-Soo Hong
    Allergy, Asthma & Immunology Research.2012; 4(6): 313.     CrossRef
  • Role of Cockroach Proteases in Allergic Disease
    Kristen Page
    Current Allergy and Asthma Reports.2012; 12(5): 448.     CrossRef
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    Kyoung Yong Jeong, Chein-Soo Hong, Joo-Shil Lee, Jung-Won Park
    Yonsei Medical Journal.2011; 52(3): 393.     CrossRef
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  • 82 Download
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Case Report

A Human Case of Clinostomum complanatum Infection in Korea
Chan-Woong Park, Jong-Soon Kim, Hyun-Soo Joo, Jin Kim
Korean J Parasitol 2009;47(4):401-404.
Published online December 2, 2009
DOI: https://doi.org/10.3347/kjp.2009.47.4.401

A 33-year-old Korean man visited a medical clinic with complaints of throat discomfort and pain for one week. The symptoms occurred one day after eating raw brackish water fish, perch. Endoscopy revealed a fluke, about 5 mm in length, attaching to and peristaltically moving on the surface of the mucosa at the arytenoid region of the larynx. Microscopically, the testes were triangular, tandem, and separated by the uterus. The ovary and cirrus pouch were placed apart from median line between testes. Numerous blood cells were observed in the ceca. The worm was identified to be Clinostomum complanatum. This is the second human case of clinostomiasis in Korea.

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    Folia Parasitologica.2025;[Epub]     CrossRef
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Mini Review

Foodborne Intestinal Flukes in Southeast Asia
Jong-Yil Chai, Eun-Hee Shin, Soon-Hyung Lee, Han-Jong Rim
Korean J Parasitol 2009;47(Suppl):S69.
Published online October 23, 2009
DOI: https://doi.org/10.3347/kjp.2009.47.S.S69

In Southeast Asia, a total of 59 species of foodborne intestinal flukes have been known to occur in humans. The largest group is the family Heterophyidae, which constitutes 22 species belonging to 9 genera (Centrocestus, Haplorchis, Heterophyes, Heterophyopsis, Metagonimus, Procerovum, Pygidiopsis, Stellantchasmus, and Stictodora). The next is the family Echinostomatidae, which includes 20 species in 8 genera (Artyfechinostomum, Acanthoparyphium, Echinochasmus, Echinoparyphium, Echinostoma, Episthmium, Euparyphium, and Hypoderaeum). The family Plagiorchiidae follows the next containing 5 species in 1 genus (Plagiorchis). The family Lecithodendriidae includes 3 species in 2 genera (Phaneropsolus and Prosthodendrium). In 9 other families, 1 species in 1 genus each is involved; Cathaemaciidae (Cathaemacia), Fasciolidae (Fasciolopsis), Gastrodiscidae (Gastrodiscoides), Gymnophallidae (Gymnophalloides), Microphallidae (Spelotrema), Neodiplostomidae (Neodiplostomum), Paramphistomatidae (Fischoederius), Psilostomidae (Psilorchis), and Strigeidae (Cotylurus). Various types of foods are sources of human infections. They include freshwater fish, brackish water fish, fresh water snails, brackish water snails (including the oyster), amphibians, terrestrial snakes, aquatic insects, and aquatic plants. The reservoir hosts include various species of mammals or birds.The host-parasite relationships have been studied in Metagonimus yokogawai, Echinostoma hortense, Fasciolopsis buski, Neodiplostomum seoulense, and Gymnophalloides seoi; however, the pathogenicity of each parasite species and host mucosal defense mechanisms are yet poorly understood. Clinical aspects of each parasite infection need more clarification. Differential diagnosis by fecal examination is difficult because of morphological similarity of eggs. Praziquantel is effective for most intestinal fluke infections. Continued efforts to understand epidemiological significance of intestinal fluke infections, with detection of further human cases, are required.

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Brief Communications

Echinostome Infections in the Striped-Field Mouse, Apodemus agrarius, and the Ussuri White-Toothed Shrew, Crocidura lasiura, Caught Near the Demilitarized Zone, Gyeonggi-do (Province), Republic of Korea
Jong-Yil Chai, Jae-Hwan Park, Bong-Kwang Jung, Sang-Mee Guk, Jae-Lip Kim, Eun-Hee Shin, Terry A. Klein, Heung-Chul Kim, Sung-Tae Chong, Luck Ju Baek, Jin-Won Song
Korean J Parasitol 2009;47(3):311-314.
Published online August 28, 2009
DOI: https://doi.org/10.3347/kjp.2009.47.3.311

A total of 1,498 small mammals (rodents and insectivores), including Apodemus agrarius (n = 1,366), Crocidura lasiura (54), Mus musculus (32), Micronytus fortis (28), Eothenomys regulus (9), Micronys minutes (6), and Cricetulus triton (3), were live-trapped in Gyeonggi-do (Province) (Paju-si, Pocheon-gun, and Yeoncheon-gun) near the demilitarized zone (DMZ) from December 2004 to September 2005. A. agrarius was found to be infected with 3 species of echinostomes (Echinostoma hortense, Echinostoma cinetorchis, and Euparyphium murinum), while C. lasiura was infected with 1 species (Echinochasmus japonicas) of echinostome. Other mammals were free from echinostome infections. Total 16 E. hortense were detected in 7 (0.5%) mice, 9 E. cinetorchis from 5 (0.4%), and 3 E. murinum from 2 (0.1%) out of 1.366 A. agrarius examined. E. japonicus was found only in 1 (1.9%; total 3 specimens) C. lasiura. These results demonstrate that A. agrarius and C. lasiura, inhabiting near the DMZ of Gyeonggi-do serve as the natural definitive hosts for several species of echinostomes, although their infection rates are low. This is the first record of natural infections of A. agrarius with E. cinetorchis and C. lasiura with E. japonicus in the Republic of Korea.

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Fishborne trematode (FBT) metacercariae were investigated in yellowfin goby, Acanthogobius flavimanus, collected from Shinan-gun and Muan-gun, Jeollanam-do (province), Korea. All collected fishes were examined using the artificial digestion method. In all of 15 gobies from Aphae-myeon in Shinan-gun, metacercariae of Stictodora spp. (334 metacercariae/fish), Heterophyes nocens (153/fish), and Heterophyopsis continua (20/fish) were detected. In 2 of 14 gobies from Jido-myeon in Shinan-gun, 8 Echinostoma hortense metacercariae in total were detected. In 15 gobies from Haeje-myeon in Muan-gun, the metacercariae of H. continua were found in 100%, Stictodora spp. in 86.7%, and H. nocens in 6.7% of fish examined. The average numbers of metacercariae per infected fish were 23.3 (H. continua), 416.0 (Stictodora spp.), and 2.0 (H. nocens), respectively. The metacercariae of E. hortense found in gobies were elliptical, with 150 × 138 ?m in average size, and had 27 collar spines on the head crown. The above results suggest that yellowfin gobies from 2 localities may be the potential infection sources of FBT. Moreover, it is proved for the first time that the yellowfin goby, A. flavimanus, acts as a second intermediate host for E. hortense.

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Original Article

Proinflammatory Cytokine and Nitric Oxide Production by Human Macrophages Stimulated with Trichomonas vaginalis
Ik-Hwan Han, Sung Young Goo, Soon-Jung Park, Se-Jin Hwang, Yong-Seok Kim, Michael Sungwoo Yang, Myoung-Hee Ahn, Jae-Sook Ryu
Korean J Parasitol 2009;47(3):205-212.
Published online August 28, 2009
DOI: https://doi.org/10.3347/kjp.2009.47.3.205

Trichomonas vaginalis commonly causes vaginitis and perhaps cervicitis in women and urethritis in men and women. Macrophages are important immune cells in response to T. vaginalis infection. In this study, we investigated whether human macrophages could be involved in inflammation induced by T. vaginalis. Human monocyte-derived macrophages (HMDM) were co-cultured with T. vaginalis. Live, opsonized-live trichomonads, and T. vaginalis lysates increased proinflammatory cytokines, such as TNF-α, IL-1β, and IL-6 by HMDM. The involvement of nuclear factor (NF)-κB signaling pathway in cytokine production induced by T. vaginalis was confirmed by phosphorylation and nuclear translocation of p65 NF-κB. In addition, stimulation with live T. vaginalis induced marked augmentation of nitric oxide (NO) production and expression of inducible NO synthase (iNOS) levels in HMDM. However, trichomonad-induced NF-κB activation and TNF-α production in macrophages were significantly inhibited by inhibition of iNOS levels with L-NMMA (NO synthase inhibitor). Moreover, pretreatment with NF-κB inhibitors (PDTC or Bay11-7082) caused human macrophages to produce less TNF-α. These results suggest that T. vaginalis stimulates human macrophages to produce proinflammatory cytokines, such as IL-1, IL-6, and TNF-α, and NO. In particular, we showed that T. vaginalis induced TNF-α production in macrophages through NO-dependent activation of NF-κB, which might be closely involved in inflammation caused by T. vaginalis.

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    Abdollah Jafarzadeh, Maryam Nemati, Ehsan Salarkia, Sonal Yadav, Najmeh Aminizadeh, Sara Jafarzadeh, Manisha Yadav
    Parasite Immunology.2023;[Epub]     CrossRef
  • In Vitro Activation of Macrophages by an MHC Class II-restricted Trichomonas Vaginalis TvZIP8-derived Synthetic Peptide
    Victor Ermilo Arana-Argáez, Emanuel Ceballos-Góngora, María Elizbeth Alvarez-Sánchez, Antonio Euan-Canto, Julio Lara-Riegos, Julio César Torres-Romero
    Immunological Investigations.2022; 51(1): 88.     CrossRef
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    Sonal Yadav, Vivek Verma, Rakesh Singh Dhanda, Sumeeta Khurana, Manisha Yadav
    Experimental Parasitology.2022; 239: 108287.     CrossRef
  • Immune cell arrival kinetics to peritoneum and role during murine-experimental trichomoniasis
    F. J. Rangel-Mata, E. E. Ávila-Muro, J. E. Reyes-Martínez, L. M. Olmos-Ortiz, M. E. Brunck, L. A. Arriaga-Pizano, P. Cuéllar-Mata
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  • Immune Response of BALB/c Mice toward Putative Calcium Transporter Recombinant Protein of Trichomonas vaginalis
    Tahali Mendoza-Oliveros, Victor Arana-Argáez, Leidi C. Alvaréz-Sánchez, Julio Lara-Riegos, María Elizbeth Alvaréz-Sánchez, Julio C. Torres-Romero
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  • Heterogeneous macrophages: Supersensors of exogenous inducing factors
    Caiyun Qian, Zehui Yun, Yudi Yao, Minghua Cao, Qiang Liu, Song Hu, Shuhua Zhang, Daya Luo
    Scandinavian Journal of Immunology.2019;[Epub]     CrossRef
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    Namarta Kalia, Jatinder Singh, Manpreet Kaur
    Frontiers in Immunology.2019;[Epub]     CrossRef
  • ReducedTrichomonas vaginalisviability in mice pretreated with parasite DNA
    Marco Antonio Barajas-Mendiola, Laura E. Castellano, Miriam Barrios-Rodiles, Martha A. Deveze-Alvarez, Eva E. Avila, Patricia Cuéllar-Mata
    Parasitology.2019; 146(13): 1636.     CrossRef
  • Trichomonas vaginalis Induces NLRP3 Inflammasome Activation and Pyroptotic Cell Death in Human Macrophages
    Angelica Montenegro Riestra, J. Andrés Valderrama, Kathryn A. Patras, Sharon D. Booth, Xing Yen Quek, Chih-Ming Tsai, Victor Nizet
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    M. Nemati, N. Malla, M. Yadav, H. Khorramdelazad, A. Jafarzadeh
    Parasite Immunology.2018;[Epub]     CrossRef
  • Trichomonas vaginalis Induces Production of Proinflammatory Cytokines in Mouse Macrophages Through Activation of MAPK and NF-κB Pathways Partially Mediated by TLR2
    Ling Li, Xin Li, Pengtao Gong, Xichen Zhang, Zhengtao Yang, Ju Yang, Jianhua Li
    Frontiers in Microbiology.2018;[Epub]     CrossRef
  • BLT1-mediated O-GlcNAcylation is required for NOX2-dependent migration, exocytotic degranulation and IL-8 release of human mast cell induced by Trichomonas vaginalis-secreted LTB4
    Arim Min, Young Ah Lee, Kyeong Ah Kim, Myeong Heon Shin
    Microbes and Infection.2018; 20(6): 376.     CrossRef
  • Effect of iNOS inhibitor LNMMA along with antibiotics Chloramphenicol or Ofloxacin in murine peritoneal macrophages regulates S.aureus infection as well as inflammation: An in vitro study
    Somrita Dey, Biswadev Bishayi
    Microbial Pathogenesis.2017; 105: 307.     CrossRef
  • Trichomonas vaginalis exosome‐like vesicles modify the cytokine profile and reduce inflammation in parasite‐infected mice
    L. M. Olmos‐Ortiz, M. A. Barajas‐Mendiola, M. Barrios‐Rodiles, L. E. Castellano, S. Arias‐Negrete, E. E. Avila, P. Cuéllar‐Mata
    Parasite Immunology.2017;[Epub]     CrossRef
  • The anti‐Trichomonas vaginalis phloroglucinol derivative isoaustrobrasilol B modulates extracellular nucleotide hydrolysis
    Camila Braz Menezes, Graziela Vargas Rigo, Henrique Bridi, Danielle da Silva Trentin, Alexandre José Macedo, Gilsane Lino von Poser, Tiana Tasca
    Chemical Biology & Drug Design.2017; 90(5): 811.     CrossRef
  • Adenosine reduces reactive oxygen species and interleukin-8 production by Trichomonas vaginalis-stimulated neutrophils
    Amanda Piccoli Frasson, Camila Braz Menezes, Gustavo Krumel Goelzer, Simone Cristina Baggio Gnoatto, Solange Cristina Garcia, Tiana Tasca
    Purinergic Signalling.2017; 13(4): 569.     CrossRef
  • Trichomonas vaginalis α-Actinin 2 Modulates Host Immune Responses by Inducing Tolerogenic Dendritic Cells via IL-10 Production from Regulatory T Cells
    Hye-Yeon Lee, Juri Kim, Jae-Sook Ryu, Soon-Jung Park
    The Korean Journal of Parasitology.2017; 55(4): 375.     CrossRef
  • SNAP23-Dependent Surface Translocation of Leukotriene B 4 (LTB 4 ) Receptor 1 Is Essential for NOX2-Mediated Exocytotic Degranulation in Human Mast Cells Induced by Trichomonas vaginalis-Secrete
    Arim Min, Young Ah Lee, Kyeong Ah Kim, Jamel El-Benna, Myeong Heon Shin, Judith A. Appleton
    Infection and Immunity.2017;[Epub]     CrossRef
  • OsmC and incomplete glycine decarboxylase complex mediate reductive detoxification of peroxides in hydrogenosomes of Trichomonas vaginalis
    Eva Nývltová, Tamara Smutná, Jan Tachezy, Ivan Hrdý
    Molecular and Biochemical Parasitology.2016; 206(1-2): 29.     CrossRef
  • Symbiotic Association with Mycoplasma hominis Can Influence Growth Rate, ATP Production, Cytolysis and Inflammatory Response of Trichomonas vaginalis
    Valentina Margarita, Paola Rappelli, Daniele Dessì, Gianfranco Pintus, Robert P. Hirt, Pier L. Fiori
    Frontiers in Microbiology.2016;[Epub]     CrossRef
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    Camila Braz Menezes, Tiana Tasca
    Biomedical Journal.2016; 39(4): 234.     CrossRef
  • Modulation of dendritic cell function by Trichomonas vaginalis-derived secretory products
    Min-Ji Song, Jong-Joo Lee, Young Hee Nam, Tae-Gyun Kim, Youn Wook Chung, Mikyoung Kim, Ye-Eun Choi, Myeong Heon Shin, Hyoung-Pyo Kim
    BMB Reports.2015; 48(2): 103.     CrossRef
  • Involvement of PI3K/AKT and MAPK Pathways for TNF-α Production in SiHa Cervical Mucosal Epithelial Cells Infected with <i>Trichomonas vaginalis</i>
    Jung-Bo Yang, Juan-Hua Quan, Ye-Eun Kim, Yun-Ee Rhee, Byung-Hyun Kang, In-Wook Choi, Guang-Ho Cha, Jae-Min Yuk, Young-Ha Lee
    The Korean Journal of Parasitology.2015; 53(4): 371.     CrossRef
  • Analysis of the Oxidative Stress Status in Nonspecific Vaginitis and Its Role in Vaginal Epithelial Cells Apoptosis
    Zhaojie Chen, Zhen Zhang, Haiyan Zhang, Beibei Xie
    BioMed Research International.2015; 2015: 1.     CrossRef
  • T. vaginalis Infection Is Associated with Increased IL-8 and TNFr1 Levels but with the Absence of CD38 and HLADR Activation in the Cervix of ESN
    Olamide D. Jarrett, Kirsten E. Brady, Sharada P. Modur, Jill Plants, Alan L. Landay, Mahmood Ghassemi, Elizabeth T. Golub, Greg T. Spear, Richard M. Novak, Clive M. Gray
    PLOS ONE.2015; 10(6): e0130146.     CrossRef
  • Prostatic Disease Associated withTrichomonas vaginalis
    Jae-Sook Ryu
    The Korean Journal of Urogenital Tract Infection and Inflammation.2014; 9(2): 61.     CrossRef
  • Immunity in urogenital protozoa
    N. Malla, K. Goyal, R. S. Dhanda, M. Yadav
    Parasite Immunology.2014; 36(9): 400.     CrossRef
  • Differential Regulation of Proinflammatory Cytokine Expression by Mitogen-Activated Protein Kinases in Macrophages in Response to Intestinal Parasite Infection
    Mei Xing Lim, Chin Wen Png, Crispina Yan Bing Tay, Joshua Ding Wei Teo, Huipeng Jiao, Norbert Lehming, Kevin Shyong Wei Tan, Yongliang Zhang, J. A. Appleton
    Infection and Immunity.2014; 82(11): 4789.     CrossRef
  • IL‐22 Levels are Associated with Trichomonas vaginalis Infection in the Lower Genital Tract
    Hadijat Moradeke Makinde, Reza Zariffard, Paria Mirmonsef, Richard M Novak, Olamide Jarrett, Alan L Landay, Gregory T Spear
    American Journal of Reproductive Immunology.2013; 70(1): 38.     CrossRef
  • IL-10 release by bovine epithelial cells cultured with Trichomonas vaginalis and Tritrichomonas foetus
    Ricardo Chaves Vilela, Marlene Benchimol
    Memórias do Instituto Oswaldo Cruz.2013; 108(1): 110.     CrossRef
  • Involvement of purinergic signaling on nitric oxide production by neutrophils stimulated with Trichomonas vaginalis
    Amanda Piccoli Frasson, Geraldo Attilio De Carli, Carla Denise Bonan, Tiana Tasca
    Purinergic Signalling.2012; 8(1): 1.     CrossRef
  • Leukotriene B4 receptors BLT1 and BLT2 are involved in interleukin-8 production in human neutrophils induced by Trichomonas vaginalis-derived secretory products
    Young Hee Nam, Arim Min, Seong Hoon Kim, Young Ah Lee, Kyeong Ah Kim, Kyoung-Ju Song, Myeong Heon Shin
    Inflammation Research.2012; 61(2): 97.     CrossRef
  • Involvement of mast cells in inflammation induced by Trichomonas vaginalis via crosstalk with vaginal epithelial cells
    I. H. HAN, S. J. PARK, M. H. AHN, J. S. RYU
    Parasite Immunology.2012; 34(1): 8.     CrossRef
  • Leukotriene B4 receptor BLT-mediated phosphorylation of NF-κB and CREB is involved in IL-8 production in human mast cells induced by Trichomonas vaginalis-derived secretory products
    Young Hee Nam, Deulle Min, Hyoung-Pyo Kim, Kyoung-Ju Song, Kyeong Ah Kim, Young Ah Lee, Seong Hoon Kim, Myeong Heon Shin
    Microbes and Infection.2011; 13(14-15): 1211.     CrossRef
  • NF-κB and CREB Are Involved in IL-8 Production of Human Neutrophils Induced byTrichomonas vaginalis-Derived Secretory Products
    Young Hee Nam, Deulle Min, Soon-Jung Park, Kyeong Ah Kim, Young Ah Lee, Myeong Heon Shin
    The Korean Journal of Parasitology.2011; 49(3): 291.     CrossRef
  • Trichomoniasis
    Jae-Sook Ryu
    Hanyang Medical Reviews.2010; 30(3): 213.     CrossRef
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  • 118 Download
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Mini Review

Trypanosome Glycosylphosphatidylinositol Biosynthesis
Yeonchul Hong, Taroh Kinoshita
Korean J Parasitol 2009;47(3):197-204.
Published online August 28, 2009
DOI: https://doi.org/10.3347/kjp.2009.47.3.197

Trypanosoma brucei, a protozoan parasite, causes sleeping sickness in humans and Nagana disease in domestic animals in central Africa. The trypanosome surface is extensively covered by glycosylphosphatidylinositol (GPI)-anchored proteins known as variant surface glycoproteins and procyclins. GPI anchoring is suggested to be important for trypanosome survival and establishment of infection. Trypanosomes are not only pathogenically important, but also constitute a useful model for elucidating the GPI biosynthesis pathway. This review focuses on the trypanosome GPI biosynthesis pathway. Studies on GPI that will be described indicate the potential for the design of drugs that specifically inhibit trypanosome GPI biosynthesis.

Citations

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    Nature Communications.2024;[Epub]     CrossRef
  • Identification of TbPBN1 in Trypanosoma brucei reveals a conserved heterodimeric architecture for glycosylphosphatidylinositol‐mannosyltransferase‐I
    Andrew Cowton, Peter Bütikofer, Robert Häner, Anant K. Menon
    Molecular Microbiology.2022; 117(2): 450.     CrossRef
  • Persistence of Trypanosoma brucei as early procyclic forms and social motility are dependent on glycosylphosphatidylinositol transamidase
    Sebastian Knüsel, Aurelio Jenni, Mattias Benninger, Peter Bütikofer, Isabel Roditi
    Molecular Microbiology.2022; 117(4): 802.     CrossRef
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    Nava Raj Poudyal, Kimberly S. Paul
    Frontiers in Cellular and Infection Microbiology.2022;[Epub]     CrossRef
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    Alyssa R. Borges, Fabian Link, Markus Engstler, Nicola G. Jones
    Frontiers in Cell and Developmental Biology.2021;[Epub]     CrossRef
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    Juan Felipe Osorio-Méndez, Ana María Cevallos
    Frontiers in Cellular and Infection Microbiology.2019;[Epub]     CrossRef
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    Fana B. Mersha, Leslie K. Cortes, Ashley N. Luck, Colleen M. McClung, Cristian I. Ruse, Christopher H. Taron, Jeremy M. Foster, Catherine FAIVRE-SARRAILH
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    Ana Luísa Malaco Morotti, Maristela Braga Martins-Teixeira, Ivone Carvalho
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    Mohamed Bessat
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    Sonali Shinde, Milsee Mol, Virashree Jamdar, Shailza Singh
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    Darren J. Creek, Jana Anderson, Malcolm J. McConville, Michael P. Barrett
    Molecular and Biochemical Parasitology.2012; 181(2): 73.     CrossRef
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    Paul F. Seke Etet, M. Fawzi Mahomoodally
    The Scientific World Journal.2012; 2012: 1.     CrossRef
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    Mauro Serricchio, Peter Bütikofer
    The FEBS Journal.2011; 278(7): 1035.     CrossRef
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    Nahid Azzouz, Faustin Kamena, Peter H. Seeberger
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    Toya Nath Baral
    Journal of Biomedicine and Biotechnology.2010; 2010: 1.     CrossRef
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    Terry K. Smith, Peter Bütikofer
    Molecular and Biochemical Parasitology.2010; 172(2): 66.     CrossRef
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Brief Communication

Metacercariae of Acanthoparyphium marilae Yamaguti, 1934 (Digenea: Echinostomatidae) were discovered in an intertidal clam, Mactra veneriformis, in a southwestern coastal area of the Republic of Korea. A total of 128 metacercariae were detected from 10 clams examined. They were round, 320 ?m in average diameter, with 23 collar spines. They were fed experimentally to chicks, and 10 days later adult flukes were obtained. The adults were morphologically characterized by the head collar with a single row of 23 dorsally uninterrupted spines, without special end group spines, a round ventral sucker, 2 round and tandem testes, and vitellaria extending at lateral fields from the posterior extremity not beyond the middle level of the posterior testis. The most characteristic feature of this species was the limited distribution of vitellaria, which differs from Acanthoparyphium tyosenense Yamaguti, 1939, the metacercariae of which are encysted in the same mollusk species. This is the first report in which the metacercariae of this species were detected, and the intertidal bivalve, M. veneriformis, has been identified as a second intermediate host for A. marilae.

Citations

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  • Acanthoparyphium shinanense n. sp. (Digenea: Echinostomatidae) from Experimental Chicks Infected with Metacercariae Encysted in Brackish Water Clams in the Republic of Korea
    Seungwan Ryoo, Bong-Kwang Jung, Taehee Chang, Sooji Hong, Hyejoo Shin, Jong-Yil Chai
    The Korean Journal of Parasitology.2021; 59(4): 341.     CrossRef
  • Prevalence and Density of Digenetic Trematode Metacercariae in Clams and Oysters from Western Coastal Regions of the Republic of Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Won-Ja Lee
    The Korean Journal of Parasitology.2017; 55(4): 399.     CrossRef
  • Clearance rate and feeding according to water temperature and salinity condition in the surf clam, Mactra veneriformis
    Joung Wook Kang, Seon Sik Lee, Kyung Nam Han
    The Korean Journal of Malacology.2014; 30(2): 101.     CrossRef
  • Korean molluscs as auxiliary hosts for parasites: A study of implications for pathogen transmission in a changing climate
    Gab-Man Park
    The Korean Journal of Malacology.2012; 28(1): 13.     CrossRef
  • 9,261 View
  • 80 Download
  • Crossref

Original Article

Effectiveness of education for control of house dust mites and cockroaches in Seoul, Korea
Kyoung Yong Jeong, In-Yong Lee, Jongweon Lee, Han-Il Ree, Chein-Soo Hong, Tai-Soon Yong
Korean J Parasitol 2006;44(1):73-79.
Published online March 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.1.73

We evaluated the efficacy of health education in reducing indoor arthropod allergens in Seoul. The mite control measures comprised the use of mite-proof mattress and pillow coverings, regular washing of potentially infested materials, maintenance of a low humidity, removal of carpets, and frequent vacuum cleaning. Cockroach control measures included trapping, application of insecticides, and protecting food. Of 201 homes enrolled in October 1999, 63 volunteers were included in a 2-year follow-up survey between April 2000 and January 2002. Before intervention, the density of mites/g of dust varied greatly; 27.1/g in children's bedding, 20/g in adult bedding, 7.2/g on the floors of children's bedrooms, 6.8/g in sofas, 5.9/g on the floors of adult's bedrooms, 3.9/g on living room floors, 3.7/g in carpets, and 1.9 mites/g on kitchen floors. The predominant mite species and house percentages infested were; Dermatophagoides farinae 93%, D. pteronyssinus 9%, and Tyrophagus putrescentiae 8%. Comparing 1999 and 2001 infestations, before and after 25 mo of education, mite abundance was reduced by 98%, from 23.7 to 0.57 mites/g of dust. In 1999, cockroaches were detected in 62% homes: 36% Blattella germanica and 35% Periplaneta spp., including 9% double infestations of B. germanica and P. americana. Following intervention, cockroach infestation rates decreased to 22% of houses in 2000 and 23% in 2001. We conclude that continuous and repetitive health education resulted in the effective control of domestic arthropods.

Citations

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  • The storage mite Tyrophagus putrescentiae induces greater lung inflammation than house dust mites in mice
    Eun-Min Kim, Ju Yeong Kim, You Shine Kwak, Myung-Hee Yi, Tai-Soon Yong
    Parasites, Hosts and Diseases.2024; 62(3): 365.     CrossRef
  • Investigating the microbiome of house dust mites in South Korea
    Myung-hee Yi, Myungjun Kim, Tai-Soon Yong, Ju Yeong Kim
    Frontiers in Allergy.2023;[Epub]     CrossRef
  • Microbiome and mycobiome interaction in house dust mites and impact on airway cells
    Ju Yeong Kim, Myung‐hee Yi, Seogwon Lee, In‐Yong Lee, Dongeun Yong, Sang Sun Yoon, Tai‐Soon Yong
    Clinical & Experimental Allergy.2021; 51(12): 1592.     CrossRef
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    Mey-Fann Lee, Yi-Hsing Chen, Shyh-Jye Lin, Hsin-Chun Liu, Tzu-Mei Lin
    Annals of Allergy, Asthma & Immunology.2019; 123(3): 301.     CrossRef
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    Hassan Nasirian
    Acta Tropica.2017; 167: 86.     CrossRef
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    Ammorn INSUNG, Jarongsak PUMNUAN, Vanna MAHAKITTIKUN, Teerapong WANGAPAI
    Journal of the Acarological Society of Japan.2016; 25(Supplement): S179.     CrossRef
  • The effects of a newsletter on bedding control on house dust mite allergen concentrations in childcare centers in Korea
    Jeonghoon Kim, Kyoung Yong Jeong, Ho-Jang Kwon, Heasuk Yang, Hye Yung Yum, Seon Ah Lee, Chae-Bong Kim, Hyunjung Kim, Wan Ryung Lim, Soyoung Hong, Kyoosang Kim
    Environmental Health and Toxicology.2015; 30: e2015008.     CrossRef
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    Anna Pomés, Luisa Karla Arruda
    Methods.2014; 66(1): 75.     CrossRef
  • IgE reactivity to Acarus siro extract in Korean dust mite allergic patients
    Mina Son, Kyoung Yong Jeong, Bum Joon Kim, Kook-Jin Lim, Jae-Hyun Lee, Jung-Won Park
    Experimental and Applied Acarology.2014; 63(1): 57.     CrossRef
  • The differences of clinical profiles by house dust mite sensitization in patients with asthmatics in Soonchunhyang University Hospital cohort
    Jung-Hyun Kim, An-Soo Jang, Shin-Ok Jeong, Young-Seok Ji, Hyun-Jung Seo, Jae-Hyung Nam, Jong-Joo Moon, Ae-Rin Baek, Jong-Sook Park, June-Hyuk Lee, Sung-Woo Park, Do-Jin Kim, Choon-Sik Park
    Allergy Asthma & Respiratory Disease.2013; 1(1): 50.     CrossRef
  • Preparation and Characterization of an Extract of German Cockroach From a Korean Source
    Kyoung Yong Jeong, Soo-Young Choi, Jae-Hyun Lee, Joo-Shil Lee, Tai-Soon Yong, Chein-Soo Hong, Jung-Won Park
    Allergy, Asthma & Immunology Research.2013; 5(2): 102.     CrossRef
  • Effect of a commercial air ionizer on dust mites Dermatophagoides pteronyssinus and Dermatophagoides farinae (Acari: Pyroglyphidae) in the laboratory
    Suhaili Zainal Abidin, Ho Tze Ming
    Asian Pacific Journal of Tropical Biomedicine.2012; 2(2): 156.     CrossRef
  • The Cockroach and Allergic Diseases
    Myung Hyun Sohn, Kyu-Earn Kim
    Allergy, Asthma & Immunology Research.2012; 4(5): 264.     CrossRef
  • Group 10 Allergens (Tropomyosins) from House-Dust Mites May Cause Covariation of Sensitization to Allergens from Other Invertebrates
    Rubaba Hamid Shafique, Muhammad Inam, Muhammad Ismail, Farhana Riaz Chaudhary
    Allergy & Rhinology.2012;[Epub]     CrossRef
  • Review on Ecology of House Dust Mites in Korea and Suggestion of a Standard Survey Method
    Tai-Soon Yong, Kyoung-Yong Jeong
    Pediatric Allergy and Respiratory Disease.2011; 21(1): 4.     CrossRef
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    Tai-Soon Yong, Kyoung Yong Jeong
    The Korean Journal of Parasitology.2009; 47(Suppl): S143.     CrossRef
  • 10,280 View
  • 96 Download
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Case Report

A human infection of Echinostoma hortense in duodenal bulb diagnosed by endoscopy
Young-Doo Chang, Woon-Mok Sohn, Jae-Hwa Ryu, Shin-Yong Kang, Sung-Jong Hong
Korean J Parasitol 2005;43(2):57-60.
Published online June 20, 2005
DOI: https://doi.org/10.3347/kjp.2005.43.2.57

As gastroduodenoscopy performed more frequently, case reports of human echinostomiasis are increasing in Korea. A Korean woman presented at a local clinic with complaints of abdominal pain and discomfort that had persisted for 2 weeks. Under gastroduodenoscopy, two motile flukes were found attached on the duodenal bulb, and retrieved with endoscopic forceps. She had history of eating raw frog meat. The two flukes were identified as Echinostoma hortense by egg morphology, 27 collar spines with 4 end-group spines, and surface ultrastructural characters. This report may prove frogs to be a source of human echinostome infections.

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  • Clonorchis sinensis and Echinostoma hortense detected by endoscopy and molecular characterization: two case reports and update on diagnosis
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    Arif Rahman Jabal, Dian Mutiasari, Hairil Akbar, M. Arfah, Marhani Marhani, Rini Rini, Nur Alam Sobak, Anggit Julianingsih Pisu, Agnes Immanuela Toemon, Arini Ratnasari
    Russian Journal of Infection and Immunity.2023; 12(4): 765.     CrossRef
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    Rafael Toledo, María Álvarez-Izquierdo, J. Guillermo Esteban, Carla Muñoz-Antoli
    Parasitology.2022; 149(10): 1319.     CrossRef
  • Morphology and Molecular Identification of Echinostoma revolutum and Echinostoma macrorchis in Freshwater Snails and Experimental Hamsters in Upper Northern Thailand
    Preeyaporn Butboonchoo, Chalobol Wongsawad, Pheravut Wongsawad, Jong-Yil Chai
    The Korean Journal of Parasitology.2020; 58(5): 499.     CrossRef
  • Fasciola hepatica infection in children actively detected in a survey in rural areas of Mardan district, Khyber Pakhtunkhawa province, northern Pakistan
    Asma W. Qureshi, Aurang Zeb, Abu Mansoor, Azam Hayat, Santiago Mas-Coma
    Parasitology International.2019; 69: 39.     CrossRef
  • Infection Status of Isthmiophora hortensis Metacercariae in Dark Sleepers, Odontobutis Species, from Some Water Systems of the Republic of Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Jung-Won Ju
    The Korean Journal of Parasitology.2018; 56(6): 633.     CrossRef
  • New Definitive Hosts and Differential Body Indices of Isthmiophora hortensis (Digenea: Echinostomatidae)
    Woon-Mok Sohn, Byoung-Kuk Na, Sung-Shik Shin
    The Korean Journal of Parasitology.2017; 55(3): 287.     CrossRef
  • Echinostoma macrorchis (Digenea: Echinostomatidae): Metacercariae in Cipangopaludina chinensis malleata Snails and Adults from Experimental Rats in Korea
    Woon-Mok Sohn, Byoung-Kuk Na
    The Korean Journal of Parasitology.2017; 55(5): 541.     CrossRef
  • Epidemiological analysis of human fascioliasis in northeastern Punjab, Pakistan
    Asma W. Qureshi, Akhtar Tanveer, Santiago Mas-Coma
    Acta Tropica.2016; 156: 157.     CrossRef
  • An update on human echinostomiasis
    R. Toledo, J. G. Esteban
    Transactions of The Royal Society of Tropical Medicine and Hygiene.2016; 110(1): 37.     CrossRef
  • A Case of Echinostoma cinetorchis (Trematoda: Echinostomatidae) Infection Diagnosed by Colonoscopy
    Woon Tae Jung, Kyeong Ju Lee, Hong Jun Kim, Tae Hyo Kim, Byoung-Kuk Na, Woon-Mok Sohn
    The Korean Journal of Parasitology.2014; 52(3): 287.     CrossRef
  • Echinostoma hortense Infection with Enteritis Diagnosed by Upper Gastrointestinal Endoscopy in a Dog
    Hiroki OKANISHI, Jun MATSUMOTO, Sadao NOGAMI, Yumiko KAGAWA, Toshihiro WATARI
    Journal of Veterinary Medical Science.2013; 75(7): 991.     CrossRef
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    Parasitology Research.2012; 111(3): 1045.     CrossRef
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    Rafael Toledo, M. Dolores Bernal, Antonio Marcilla
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    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho
    The Korean Journal of Parasitology.2009; 47(3): 307.     CrossRef
  • Foodborne Intestinal Flukes in Southeast Asia
    Jong-Yil Chai, Eun-Hee Shin, Soon-Hyung Lee, Han-Jong Rim
    The Korean Journal of Parasitology.2009; 47(Suppl): S69.     CrossRef
  • ECHINOSTOMA HORTENSE ASADA INFECTION IN THE DUODENUM: INCIDENTAL FINDINGS DURING ROUTINE GASTROINTESTINAL ENDOSCOPY
    Toshiaki Tanaka, Tomoari Kamada, Hideki Koga, Aki Tanaka, Noriaki Manabe, Jiro Hata, Hiroaki Kusunoki, Manabu Ishii, Motonori Sato, Kenichi Tarumi, Akiko Shiotani, Tetsuya Okino, Ken Haruma
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Original Article

Susceptibility of several strains of mice to Echinostoma hortense infection
Kyu-Jae Lee, Seung Kyu Park, Jee Aee Im, Soo Kie Kim, Geun Ha Kim, Gwang Young Kim, Eun Ju Yang, Yong-Suk Ryang
Korean J Parasitol 2004;42(2):51-56.
Published online June 20, 2004
DOI: https://doi.org/10.3347/kjp.2004.42.2.51

Susceptibilities of 5 different mice strains, including C3H/HeN, BALB/c, C57BL6, FvB and ICR, to Echinostoma hortense infection, was evaluated. The worm expulsion rate, worm size and egg production were observed from 1 to 8 weeks after infection with 30 metacercariae. C3H/HeN and ICR mice showed the highest worm maturation rates. The worm recovery rate and the number of eggs per gram (EPG) of feces was also higher in C3H/HeN and ICR mice than in BALB/c, C57BL6, and FvB mice. It is suggested that E. hortense is highly infectious to ICR and C3H/HeN mice, but not to the other strains of mice. Based on the results obtained, we believe that the susceptibility of different mouse strains to E. hortense infection is dependent on the genetic and immunologic background of mice.

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Brief Communications

Clonorchis sinensis metacercarial infection in the pond smelt Hypomesus olidus and the minnow Zacco platypus collected from the Soyang and Daechung Lakes
Jae-Hwan Park, Sang-Mee Guk, Tae-Yun Kim, Eun-Hee Shin, Aifen Lin, Ji-Yeon Park, Jae-Lip Kim, Sung-Tae Hong, Jong-Yil Chai
Korean J Parasitol 2004;42(1):41-44.
Published online March 20, 2004
DOI: https://doi.org/10.3347/kjp.2004.42.1.41

The pond smelt Hypomesus olidus and minnow Zacco platypus were collected from the Soyang and Daechung Lakes in January 2003, and their metacercarial infections was examined by the muscle compression and artificial digestion techniques. In the Soyang Lake, 161 metacercariae of Clonorchis sinensis (0.35 per fish) were harvested from 459 pond smelts examined. Also, 13 metacercariae of C. sinensis (0.43 per fish), 1 of Metagonimus sp., 4 of Echinostoma sp., 148 of Centrocestus armatus and 44 unidentified species were collected from 30 minnows. In the Daechung Lake, 369 metacercariae of C. sinensis (3.69 per fish) and 51 unidentified species were recovered from 100 pond smelts. The metacercariae of C. sinensis were fed to experimental rats, in which the adult flukes were identified. The pond smelts and minnows collected from the Soyang and Daechung Lakes were verified to be the second intermediate hosts and the sources of human C. sinensis infection.

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A human case of Echinostoma hortense (Trematoda: Echinostomatidae) infection diagnosed by gastroduodenal endoscopy in Korea
Chang-Min Cho, Won-Young Tak, Young-Oh Kweon, Sung-Kook Kim, Yong-Hwan Choi, Hyun-Hee Kong, Dong-Il Chung
Korean J Parasitol 2003;41(2):117-120.
Published online June 20, 2003
DOI: https://doi.org/10.3347/kjp.2003.41.2.117

A human Echinostoma hortense infection was diagnosed by gastroduodenoscopy. An 81-year-old Korean male, living in Yeongcheon-shi, Gyeongsangbuk-do and with epigastric discomfort of several days duration, was subjected to upper gastrointestinal endoscopy. He was in the habit of eating fresh water fish. Two live worms were found in the duodenal bulb area and were removed using an endoscopic forcep. Based on their morphological characteristics, the worms were identified as E. hortense. The patient was treated with praziquantel 10 mg/kg as a single dose. The source of the infection in this case remains unclear, but the fresh water fish consumed, including the loach, may have been the source. This is the second case of E. hortense infection diagnosed by endoscopy in Korea.

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    Heung Up Kim
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  • Morphology and Molecular Identification of Echinostoma revolutum and Echinostoma macrorchis in Freshwater Snails and Experimental Hamsters in Upper Northern Thailand
    Preeyaporn Butboonchoo, Chalobol Wongsawad, Pheravut Wongsawad, Jong-Yil Chai
    The Korean Journal of Parasitology.2020; 58(5): 499.     CrossRef
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    Asma W. Qureshi, Aurang Zeb, Abu Mansoor, Azam Hayat, Santiago Mas-Coma
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    Ranjit Sah, Shusila Khadka, Rabin Hamal, Sagar Poudyal
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Original Article

Tegumental ultrastructure of the juvenile and adult Himasthla alincia (Digenea: Echinostomatidae)
Eun-Taek Han, Kye-Young Han, Jong-Yil Chai
Korean J Parasitol 2003;41(1):17-25.
Published online March 20, 2003
DOI: https://doi.org/10.3347/kjp.2003.41.1.17

The tegumental ultrastructure of juvenile and adult Himasthla alincia (Digenea: Echinostomatidae) was observed by scanning electron microscopy. One-, 5- (juveniles) and 20-day-old worms (adults) were harvested from chicks experimentally fed metacercariae from a bivalve, Mactra veneriformis. The juvenile worms were elongated and curved ventrally. The head crown bore 31 collar spines, arranged in a single row. The lip of the oral sucker had 12 paired, and 3 single type I sensory papillae, and the ventral sucker had about 25 type II sensory papillae. The anterolateral surface between the two suckers was densely packed with tegumental spines with 4-7 pointed tips. The adult worms were more elongated and filamentous, and had severe transverse folds over the whole body surface. On the head crown and two suckers, type I and II sensory papillae were more densely distributed than in the juvenile worms. Retractile brush-like spines, with 8-10 digits, were seen on the anterolateral surface, whereas claw-shaped spines, with 2-5 digits, were sparsely distributed posteriorly to the ventral sucker. The cirrus characteristically protruded out, and was armed with small spines distally. The surface ultrastructure of H. alincia was shown to be unique among echinostomes, especially in the digitation of its tegumental spines, the distribution of sensory papillae and by severe folds of the tegument.

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    Experimental Parasitology.2010; 125(3): 304.     CrossRef
  • Centrocestus formosanus (Digenea: Heterophyidae) Encysted in the Freshwater Fish, Puntius brevis, from Lao PDR
    Eun-Taek Han, Eun-Hee Shin, Souvanny Phommakorn, Bounthong Sengvilaykham, Jae-Lip Kim, Han-Jong Rim, Jong-Yil Chai
    The Korean Journal of Parasitology.2008; 46(1): 49.     CrossRef
  • Mactra veneriformis, an Intertidal Clam, as a New Second Intermediate Host for Acanthoparyphium marilae (Digenea: Echinostomatidae)
    Eun-Taek Han, Jong-Yil Chai
    The Korean Journal of Parasitology.2008; 46(2): 101.     CrossRef
  • FIRST RECORD AND DESCRIPTION OF METACERCARIAE OF CURTUTERIA ARGUINAE N. SP. (DIGENEA: ECHINOSTOMATIDAE), PARASITE OF COCKLES CERASTODERMA EDULE (MOLLUSCA: BIVALVIA) IN ARCACHON BAY, FRANCE
    Céline Desclaux, Fernanda Russell-Pinto, Xavier de Montaudouin, Guy Bachelet
    Journal of Parasitology.2006; 92(3): 578.     CrossRef
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Mini Review

Tegumental ultrastructure of Echinoparyphium recurvatum according to developmental stages
Woon-Mok Sohn, Ho-Choon Woo, Sung-Jong Hong
Korean J Parasitol 2002;40(2):67-73.
Published online June 30, 2002
DOI: https://doi.org/10.3347/kjp.2002.40.2.67

The present study was performed to observe tegumental ultrastructure of Echinoparyphium recurvatum according to developmental stages. Worms (1, 3, 5 and 15-day old) were recovered from chicks experimentally infected with metacercariae from Radix auricularia coreana. One-day old worms were elongated and ventrally concave, and covered with peg-like tegumental spines except the adjacent areas of the head crown and excretory pore. Type I sensory papillae were distributed on the lip of the oral sucker, and grouped ciliated papillae were around the oral sucker. Peg-like tegumental spines were densely distributed on the anterior surface of the ventral sucker level. The ventral sucker had an aspinous tegument and no sensory papillae. Tegumental spines on the posterior surface of the ventral sucker level were sparsely distributed and disappeared posteriorly. In 3 and 5-day old worms, the tegument around the oral sucker was aspinose and wrinkled concentrically. The ventral sucker had a wrinkled tegument and many bulbous papillae. Type I sensory papillae were distributed between the bulbous papillae. Tegumental spines were spade-shaped with a terminal tip. A total of 45 collar spines including 4 end group ones on both ventral corners was alternately arranged in 2 rows. The 15-day old worms were very stout and their tegumental spines were tongue-shaped without a terminal tip. From the above results, it is confirmed that the surface ultrastructure of E. recurvatum was generally similar to that of other echinostomatid flukes. However, some features, i.e., morphological change of tegumental spines and appearence of sensory papillae on the ventral sucker according to development, and number, shape and arrangement of collar spines, were characteristic, which may be of taxonomic and bioecological significance.

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  • Morphological and molecular characterization of Acanthostomum species with Plesiomonas shigelloides coinfection: Immunological and histopathological appraisal in Bagrus bajad
    Marwa M. Attia, Abdullah Albaqami, Rania I. Mohamed, Hanim S. Heikal, Asmaa W. Soliman, Mohamed Abdelsalam
    Microbial Pathogenesis.2025; 200: 107365.     CrossRef
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    Sofia A. Denisova, Natalia N. Shunatova, Vladimir V. Lebedenkov, Sergei V. Shchenkov
    Canadian Journal of Zoology.2023; 101(7): 579.     CrossRef
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    S.A. Denisova, S.V. Shchenkov
    Journal of Helminthology.2020;[Epub]     CrossRef
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    Jane Huffman, Bernard Fried
    Acta Parasitologica.2012;[Epub]     CrossRef
  • Surface Ultrastructure of Juvenile and Adult Acanthoparyphium tyosenense (Digenea: Echinostomatidae)
    Eun-Taek Han, Moon-Seok Choi, Sung-Yil Choi, Jong-Yil Chai
    Journal of Parasitology.2011; 97(6): 1049.     CrossRef
  • Scanning electron microscopy of adult Echinoparyphium recurvatum (Von Linstow, 1873) (Digenea: Echinostomatidae) from Britain
    A.M. McCarthy
    Journal of Helminthology.2011; 85(4): 453.     CrossRef
  • Identification of antigenic proteins from Echinostoma caproni (Trematoda) recognized by mouse immunoglobulins M, A and G using an immunoproteomic approach
    J. SOTILLO, L. VALERO, M. M. SÁNCHEZ DEL PINO, B. FRIED, J. G. ESTEBAN, A. MARCILLA, R. TOLEDO
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  • Developmental and Functional Ultrastructure of Ornithodiplostomum ptychocheilus Diplostomula (Trematoda: Strigeoidea) during Invasion of the Brain of the Fish Intermediate Host, Pimephales promelas
    David Bruce Conn, Cameron P. Goater, Douglas Bray
    Journal of Parasitology.2008; 94(3): 635.     CrossRef
  • Developmental and Functional Ultrastructure of Ornithodiplostomum ptychocheilus Diplostomula (Trematoda: Strigeoidea) during Invasion of the Brain of the Fish Intermediate Host, Pimephales promelas
    David Bruce Conn, Cameron P. Goater, Douglas Bray
    Journal of Parasitology.2008; 94(3): 635.     CrossRef
  • FIRST RECORD AND DESCRIPTION OF METACERCARIAE OF CURTUTERIA ARGUINAE N. SP. (DIGENEA: ECHINOSTOMATIDAE), PARASITE OF COCKLES CERASTODERMA EDULE (MOLLUSCA: BIVALVIA) IN ARCACHON BAY, FRANCE
    Céline Desclaux, Fernanda Russell-Pinto, Xavier de Montaudouin, Guy Bachelet
    Journal of Parasitology.2006; 92(3): 578.     CrossRef
  • MORPHOLOGICAL OBSERVATIONS OF ECHINOCHASMUS JAPONICUS CERCARIAE AND THE IN VITRO MAINTENANCE OF ITS LIFE CYCLE FROM CERCARIAE TO ADULTS
    Min-Ho Choi, Sae Hoon Kim, Jong-Hoon Chung, Hye-Jin Jang, Joon-Ho Eom, Byung-Suk Chung, Woon-Mok Sohn, Jong-Yil Chai, Sung-Tae Hong
    Journal of Parasitology.2006; 92(2): 236.     CrossRef
  • Tegumental ultrastructure of the juvenile and adult Himasthla alincia (Digenea: Echinostomatidae)
    Eun-Taek Han, Kye-Young Han, Jong-Yil Chai
    The Korean Journal of Parasitology.2003; 41(1): 17.     CrossRef
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Brief Communication

Corbicula fluminea (Bivalvia: Corbiculidae): a possible second molluscan intermediate host of Echinostoma cinetorchis (Trematoda: Echinostomatidae) in Korea
Pyung-Rim Chung, Younghun Jung, Yun-Kyu Park, Myung-Gi Hwang, Chin-Thack Soh
Korean J Parasitol 2001;39(4):329-332.
Published online December 31, 2001
DOI: https://doi.org/10.3347/kjp.2001.39.4.329

More than 1,500 clams of Corbicula fluminea, the most favorable food source of freshwater bivalves in Korea, were collected from 5 localities to examine cercarial and metacercarial infection with Echinostoma cinetorchis. Although 3 clams infected with suspicious E. cinetorchis metacercariae out of 200 specimens collected at Kangjin, Chollanam-do were detected, no cercarial and metacercarial infections with E. cinetorchis were observed in field-collected Corbicula specimens. In the susceptibility experiments with laboratory-reared clams, those infected with miracidia of E. cinetorchis did not release their cercariae up to 60 days after infection. To confirm the identity of second intermediate host of E. cinetorchis experimentally, a total of 30 clams were exposed to the cercariae from Segmentina hemisphaerula that had been infected with miracidia of E. cinetorchis. The clams were susceptible to cercariae of E. cinetorchis with an infection rate of 93.3%. Metacercariae from clams taken more than 7 days after cercarial exposure were fed to rats (S/D strain), and adult worms of E. cinetorchis, characterized by 37-38 collar spines on the head crown, were recovered from the ileocecal regions. This is the first report of C. fluminea as a possible second intermediate host of E. cinetorchis.

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  • Lower parasite pressure in invasive freshwater bivalves than in sympatric native Unionidae mussels in southern European lakes
    Binglin Deng, Nicoletta Riccardi, Maria Urbańska, Timo J. Marjomäki, Wojciech Andrzejewski, Jouni Taskinen
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    Alexander V. Kropotin, Yulia V. Bespalaya, Alexander V. Kondakov, Irina S. Khrebtova, Ilya V. Vikhrev, Ivan N. Bolotov
    Ecologica Montenegrina.2023; 62: 1.     CrossRef
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    Uma Sabapathy Allen
    CABI Compendium.2022;[Epub]     CrossRef
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    Fabiana Freitas
    CABI Compendium.2022;[Epub]     CrossRef
  • Parasites of Aquatic Exotic Invertebrates: Identification of Potential Risks Posed to the Great Lakes
    Sergey E. Mastitsky, Alexander Y. Karatayev, Lyubov E. Burlakova
    Human and Ecological Risk Assessment: An International Journal.2014; 20(3): 743.     CrossRef
  • Korean molluscs as auxiliary hosts for parasites: A study of implications for pathogen transmission in a changing climate
    Gab-Man Park
    The Korean Journal of Malacology.2012; 28(1): 13.     CrossRef
  • ENCYSTMENT AND METACERCARIAE DEVELOPMENT OF ECHINOSTOMA CINETORCHIS CERCARIAE IN AN IN VITRO CULTURE SYSTEM
    Yun-Kyu Park, Myung-Ki Hwang, Pyung-Rim Chung
    Journal of Parasitology.2006; 92(5): 1010.     CrossRef
  • Host Specificity of Pisidium coreanum (Bivalvia: Sphaeriidae) to Larval Infection with a Human Intestinal Fluke Echinostoma cinetorchis (Trematoda: Echinostomatidae) in Korea
    Y. K. Park, C. T. Soh, G. M. Park, M. K. Hwang, P. R. Chung
    Journal of Parasitology.2006; 92(5): 1118.     CrossRef
  • 8,263 View
  • 87 Download
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Original Article
Austropeplea ollula (Pulmonata: Lymnaeidae): A new molluscan intermediate host of a human intestinal fluke, Echinostoma cinetorchis (Trematoda: Echinostomatidae) in Korea
Pyung-Rim Chung, Younghun Jung, Yun-Kyu Park, Myung-Ki Hwang
Korean J Parasitol 2001;39(3):247-253.
Published online September 30, 2001
DOI: https://doi.org/10.3347/kjp.2001.39.3.247

Three freshwater snail species of the family Lymnaeidae have been reported from Korea, Radix auricularia coreana, Austropeplea ollula and Fossaria truncatula. Out of 3 lymnaeid snail species, A. ollula was naturally infected with the Echinostoma cinetorchis cercariae (infection rate = 0.7%). In the experiments with the laboratory-bred snails, F. truncatula as well as A. ollula was also susceptible to the E. cinetorchis miracidia with infection rates of 25% and 40%, respectively. All of three lymnaeid snail species exposed to the E. cinetorchis cercariae were infected with the E. cinetorchis metacercariae. It is evident that A. ollula acts as the first molluscan intermediate host of E. cinetorchis in Korea, and F. truncatula may be a possible candidate for the first intermediate host of this intestinal fluke. Also, three lymnaeid snail species targeted were experimentally infected with E. cinetorchis metacercariae.

Citations

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    Biology.2025; 14(8): 1101.     CrossRef
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    Antonio A. Vázquez, Elodie Chapuis, Jorge Sánchez, Pilar Alda, Dominique Faugère, Mónica Sánchez, Léa Souq, Joaquín López-Soriano, Sergio Quiñonero-Salgado, Nicolás Bonel, Jean-Pierre Pointier, Annia Alba, Sylvie Hurtrez-Boussès
    Parasites & Vectors.2024;[Epub]     CrossRef
  • Morphology and Molecular Identification of Echinostoma revolutum and Echinostoma macrorchis in Freshwater Snails and Experimental Hamsters in Upper Northern Thailand
    Preeyaporn Butboonchoo, Chalobol Wongsawad, Pheravut Wongsawad, Jong-Yil Chai
    The Korean Journal of Parasitology.2020; 58(5): 499.     CrossRef
  • Examining the phylogeny of the Australasian Lymnaeidae (Heterobranchia: Pulmonata: Gastropoda) using mitochondrial, nuclear and morphological markers
    Louise Puslednik, Winston F. Ponder, Mark Dowton, Andrew R. Davis
    Molecular Phylogenetics and Evolution.2009; 52(3): 643.     CrossRef
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  • 79 Download
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