A total of 53 patients infected with Taenia solium were treated with praziquantel in two different dose levels.
Twenty-six cases were treated with praziquantel in a single oral dose of 5 mg/kg body weight. All cases except one were completely cured. The cure rate was 96.2 per cent. The other 27 cases were treated with a single dose of 10 mg/kg body weight. All cases were completely cured and revealed a cure rate of 100 per cent. Side effects were mild and transient.
About half of the cases complained of a mild abdominal pain.
Soft stool or diarrhea and dizziness were observed in some cases. Tests on clinical hematology, serum biochemistry and urinalysis were performed immediately before and one day after treatment in all cases. There were no significant abnormalities detected in these tests.
Citations
Citations to this article as recorded by
Localization of Praziquantel Production and Clonorchiasis Control Program in Korea, 1970s~1980s Jungje PARK, Junho JUNG Korean Journal of Medical History.2021; 30(2): 317. CrossRef
In Silico Chemogenomics Drug Repositioning Strategies for Neglected Tropical Diseases Carolina Horta Andrade, Bruno Junior Neves, Cleber Camilo Melo-Filho, Juliana Rodrigues, Diego Cabral Silva, Rodolpho Campos Braga, Pedro Vitor Lemos Cravo Current Medicinal Chemistry.2019; 26(23): 4355. CrossRef
Praziquantel Treatment in Trematode and Cestode Infections: An Update Jong-Yil Chai Infection & Chemotherapy.2013; 45(1): 32. CrossRef
A Review of the Pharmacokinetic Implications of Schistosomiasis Kyle J. Wilby, Samuel E. Gilchrist, Mary H. H. Ensom Clinical Pharmacokinetics.2013; 52(8): 647. CrossRef
Food-Borne Parasitic Diseases Han-Jong Rim Journal of the Korean Medical Association.2007; 50(11): 984. CrossRef
Human cysticercosis: Parasitology, pathology, clinical manifestations and available treatment G. Webbe Pharmacology & Therapeutics.1994; 64(1): 175. CrossRef
Human fascioliasis successfully treated with triclabendazole P. P. Laird, J. C. Boray Australian and New Zealand Journal of Medicine.1992; 22(1): 45. CrossRef
Current status of medicinal research in helminth diseases Sudhir K. Singh, Satyavan Sharma Medicinal Research Reviews.1991; 11(6): 581. CrossRef
Efficacy of low doses of praziquantel in taeniasis Zbigniew S. Pawłowski Acta Tropica.1990; 48(2): 83. CrossRef
Cestode infections in Korea D Y Min The Korean Journal of Parasitology.1990; 28(Suppl): 123. CrossRef
Clinical study evaluating efficacy of praziquantel in clonorchiasis B G Yangco, C De Lerma, G H Lyman, D L Price Antimicrobial Agents and Chemotherapy.1987; 31(2): 135. CrossRef
TREATMENT OF TAENIA SOLIUM INFECTIONS Frank Richards, PeterM. Schantz The Lancet.1985; 325(8440): 1264. CrossRef
Studies on intestinal trematodes in Korea XVIII. Effects of praziquantel in the treatment of Fibricola seoulensis infection in albino rats Soon Hyung Lee, Jong Yil Chai, Byoug Seol Seo The Korean Journal of Parasitology.1985; 23(1): 41. CrossRef
Praziquantel Peter Andrews, Herbert Thomas, Rolf Pohlke, JÜRgen Seubert Medicinal Research Reviews.1983; 3(2): 147. CrossRef
Therapeutic trial of praziquantal (Embay 8440; Biltricide®) on the dermal and cerebral human cysticercosis Han Jong Rim, Joon Sang Lee, Kyoung Hwan Joo, Soo Jin Kim, Chang Ryong Won, Chang Yun Park The Korean Journal of Parasitology.1982; 20(2): 169. CrossRef
Clinical evaluation of the therapeutic efficacy of praziquantel (Embay 8440) againstClonorchis sinensisinfection in man Han-Jong Rim, Kwang-Sa Lyu, Joon-Sang Lee, Kyoung-Hwan Joo Annals of Tropical Medicine & Parasitology.1981; 75(1): 27. CrossRef
Effect of praziquantel on adultEchinococcus granulosus in vitro: Scanning electron microscopy George A. Conder, Alan A. Marchiondo, Ferron L. Andersen Zeitschrift f�r Parasitenkunde Parasitology Research.1981; 66(2): 191. CrossRef
