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Original Article

Risk of Recrudescence of Lymphatic Filariasis after Post-MDA Surveillance in Brugia malayi Endemic Belitung District, Indonesia
Santoso, Yahya, Yanelza Supranelfy, Nungki Hapsari Suryaningtyas, Yulian Taviv, Aprioza Yenni, Maya Arisanti, Rika Mayasari, Vivin Mahdalena, Rizki Nurmaliani, Marini, K. Krishnamoorthy, Helena Ullyartha Pangaribuan
Korean J Parasitol 2020;58(6):627-634.
Published online December 29, 2020
DOI: https://doi.org/10.3347/kjp.2020.58.6.627
Belitung district in Bangka-Belitung Province, Indonesia with a population of 0.27 million is endemic for Brugia malayi and 5 rounds of mass drug administration (MDA) were completed by 2010. Based on the results of 3 transmission assessment surveys (TAS), the district is declared as achieving elimination of lymphatic filariasis (LF) in 2017. The findings of an independent survey conducted by the National Institute of Health Research and Development (NIHRD) in the same year showed microfilaria (Mf) prevalence of 1.3% in this district. In 2019, NIHRD conducted microfilaria survey in 2 villages in Belitung district. Screening of 311 and 360 individuals in Lasar and Suak Gual villages showed Mf prevalence of 5.1% and 2.2% with mean Mf density of 120 and 354 mf/ml in the respective villages. Mf prevalence was significantly higher among farmers and fishermen compared to others and the gender specific difference was not significant. The results of a questionnaire based interview showed that 62.4% of the respondents reported to have participated in MDA in Lasar while it was 57.7% in Suak Gual village. About 42% of the Mf positive cases did not participate in MDA. Environmental surveys identified many swampy areas supporting the breeding of Mansonia vector species. Persistence of infection is evident and in the event of successful TAS3 it is necessary to monitor the situation and plan for focal MDA. Appropriate surveillance strategies including xenomonitoring in post-MDA situations need to be developed to prevent resurgence of infection. Possible role of animal reservoirs is discussed.

Citations

Citations to this article as recorded by  Crossref logo
  • Lymphatic filariasis transmission 10 years after stopping mass drug administration in the Gomoa west district of Ghana
    Christian Akuamoah Boateng, Millicent Selassie Afatodzie, Angus McLure, Bethel Kwansa-Bentum, Dziedzom K. de Souza
    International Journal of Infectious Diseases.2025; 152: 107790.     CrossRef
  • Xenomonitoring as an epidemiological tool supporting post-stop surveillance of albendazole-ivermectin mass drug distribution in the Bougouni-Yanfolila evaluation unit, Sikasso, Mali, in 2023
    Lamine Soumaoro, Housseini Dolo, Yaya Ibrahim Coulibaly, Siaka Yamoussa Coulibaly, Salif Seriba Doumbia, Moussa Sangaré, Abdallah Amadou Diallo, Abdoul Fatah Diabaté, Michel Emmanuel Coulibaly, Ibrahima Dolo, Massitan Dembélé, Alpha Seydou Yaro, Thomas Nu
    BMC Infectious Diseases.2025;[Epub]     CrossRef
  • Current perspectives in the epidemiology and control of lymphatic filariasis
    Dziedzom K. de Souza, Moses J. Bockarie, Louisa A. Messenger
    Clinical Microbiology Reviews.2025;[Epub]     CrossRef
  • Evaluating the effectiveness of mass drug administration on lymphatic filariasis transmission and assessment of post-mass drug administration surveillance in Nigeria’s Federal Capital Territory
    Juliana Ajuma Amanyi-Enegela, Joseph Kumbur, Faizah Okunade, Donald Ashikeni, Rinpan Ishaya, Girija Sankar, William Enan Adamani, Moses Aderogba, Louise Makau-Barasa, Achai Emmanuel, Bosede Eunice Ogundipe, Chinwe Okoye, Babar Qureshi
    Infectious Diseases of Poverty.2025;[Epub]     CrossRef
  • Field Validation of Post-MDA LF Surveillance by using Molecular Xeno-monitoring: Preliminary Study in Belitung District, Indonesia
    Tri Wahono, Mara Ipa, Triwibowo Ambar Garjito, Yuneu Yuliasih, Agung Puja Kesuma, Muhammad Fajri Rokhmad, Sunardi Sunardi, Hafiz Permana Putra
    Journal of Multidisciplinary Applied Natural Science.2025;[Epub]     CrossRef
  • A Review of Bed Nets Usage and Sewerage Conditions as Risk Factors for Lymphatic Filariasis in Developing Countries
    Muhafasya Karunia Azzahra, Diva Alishya Shafwah, Cresti Sukmadevi Sondakh, Retno Adriyani
    JURNAL KESEHATAN LINGKUNGAN .2024; 16(1): 89.     CrossRef
  • Lymphatic Filariasis Elimination Status: Wuchereria bancrofti Infections in Human Populations after Five Effective Rounds of Mass Drug Administration in Zambia
    Belem Blamwell Matapo, Evans Mwila Mpabalwani, Patrick Kaonga, Martin Chitolongo Simuunza, Nathan Bakyaita, Freddie Masaninga, Namasiku Siyumbwa, Seter Siziya, Frank Shamilimo, Chilweza Muzongwe, Enala T. Mwase, Chummy Sikalizyo Sikasunge
    Tropical Medicine and Infectious Disease.2023; 8(7): 333.     CrossRef
  • Vector Surveillance for Lymphatic Filariasis After Mass Drug Administration in an Endemic Area: A Case Study in Bekasi
    Endang Puji Astuti, Joni Hendri, Mara Ipa, Andri Ruliansyah, Triwibowo Ambar Garjito
    JURNAL KESEHATAN LINGKUNGAN .2023; 15(2): 134.     CrossRef
  • Finding and eliminating the reservoirs: Engage and treat, and test and treat strategies for lymphatic filariasis programs to overcome endgame challenges
    Dziedzom K. de Souza, Joseph Otchere, Jeffrey G. Sumboh, Odame Asiedu, Joseph Opare, Kofi Asemanyi-Mensah, Daniel A. Boakye, Katherine M. Gass, Elizabeth F. Long, Collins S. Ahorlu
    Frontiers in Tropical Diseases.2022;[Epub]     CrossRef
  • 7,347 View
  • 197 Download
  • 4 Web of Science
  • Crossref

Mini Review

Current Status of Parasite Infections in Indonesia: A Literature Review
Juyoung Lee, Jae-Sook Ryu
Korean J Parasitol 2019;57(4):329-339.
Published online August 31, 2019
DOI: https://doi.org/10.3347/kjp.2019.57.4.329
Indonesia and South Korea have become inseparable in various respects since the 2 countries established diplomatic relation in 1973. Indonesia is a tropical region that stretches across the equator, comprised of 5 main islands (Java, Kalimantan, Sumatra, Sulawesi, and Papua) and 4 archipelagoes (Riau, Bangka Belitung, Nusa Tenggara, and Maluku). As most population of Eastern Indonesia (Sulawesi, Papua and Nusa Tenggara & Maluku) live in poor areas, it is expected that there will be many parasites. Nevertheless, little is known about the status of parasites in Indonesia. This study examines the prevalences of malaria and lymphatic filaria, which are prevalent in Indonesia, as well as those of soil-transmitted-helminths (STH). As a result, the Plasmodium falciparum and P. vivax case loads are almost equal. The current prevalence of P. vivax is uniformly low (<5%) in all age groups and annual parasite incidence (API) showed decreasing tendency as 0.84 per 1,000 population in 2016. However, more than 65 million people still live in malaria epidemic regions. Lymphatic filariasis remains an important public health problem and 236 cities were classified as endemic areas in 514 cities/districts in 2017. It is difficult to ascertain the current prevalence rate of STH in Indonesia, although West Sumba and Southwest Sumba in East Nusa Tenggara reported prevalence rate of more than 20%. The study also considers the (sero) prevalences of other parasites identified in Indonesia. This report should be useful not only to parasitologists but also to travelers and people with business in Indonesia.

Citations

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  • Evaluation of the malaria elimination programme in Muara Enim Regency: a qualitative study from Indonesia
    Hamzah Hasyim, Heni Marini, Misnaniarti Misnaniarti, Rostika Flora, Iche Andriyani Liberty, Ahmed Elagali, Hartoni Hartoni, Fadhilah Eka Maharani
    Malaria Journal.2024;[Epub]     CrossRef
  • Malaria elimination in West Java, Indonesia: A descriptive-and-qualitative study
    Nisa Fauziah, Fedri Ruluwedrata Rinawan, Naufal Fakhri Nugraha, Lia Faridah, Karomahul Malaya Jati, Angelina Dakosta, Mahatyanta Kalya Santika, Muhammad Yusuf Zakiyyudin, Ahmad Muhsin, Kiky Furbani Rizkillah, Miftahul Nurun Nisa, Ryan Bayusantika Ristandi
    Journal of Vector Borne Diseases.2024; 61(2): 183.     CrossRef
  • Effect of preventive chemotherapy for neglected tropical diseases in Indonesia from 1992 to 2022: A systematic review and meta‐analysis
    Elsa Herdiana Murhandarwati, Ari Probandari, Rizqiani Amalia Kusumasari, Astri Ferdiana, Christina Yeni Kustanti, Kharisma Dewi, Siti Nadia Tarmizi, Luh Putu Lila Wulandari, Gill Schierhout, Lucia Romani, John Kaldor, Susana Vaz Nery
    Tropical Medicine & International Health.2024; 29(12): 995.     CrossRef
  • Comparison of the combinations of water and ethanol extract of Strychnos ligustrina blum wood with Dihydroartemisinin- Piperaquin Phosphate (DHP) as an anti-malaria in mice infected P. berghei ANKA
    U Cahyaningsih, S Sa’diah, W Syafii, R K Sari, A J Maring, A B Nugraha
    IOP Conference Series: Earth and Environmental Science.2023; 1174(1): 012015.     CrossRef
  • Mapping schistosomiasis risk in Southeast Asia: a systematic review and geospatial analysis
    Can Luo, Yan Wang, Qing Su, Jie Zhu, Shijing Tang, Robert Bergquist, Zhijie Zhang, Yi Hu
    International Journal of Epidemiology.2023; 52(4): 1137.     CrossRef
  • Mono-Parasitic and Poly-Parasitic Intestinal Infections among Children Aged 36–45 Months in East Nusa Tenggara, Indonesia
    Alpha F. Athiyyah, Ingrid S. Surono, Reza G. Ranuh, Andy Darma, Sukmawati Basuki, Lynda Rossyanti, Subijanto M. Sudarmo, Koen Venema
    Tropical Medicine and Infectious Disease.2023; 8(1): 45.     CrossRef
  • The first study on the prevalence of gastrointestinal parasites in owned and sheltered cats in Yangon, Myanmar
    Babi Kyi Soe, Khin Su Hlaing, Toe Win Naing, Zin Hnin Thaw, Win Myint
    Veterinary World.2023; : 414.     CrossRef
  • Biocontrol of Bacillus cereus for Anopheles sp larvae
    R A Mogea, Y Fitriani, N Rumalolas, Y S Salosa
    IOP Conference Series: Earth and Environmental Science.2023; 1192(1): 012027.     CrossRef
  • Prediction of Hemoglobin Levels and Eosinophil Counts Due to Soil Transmitted Helminths (STH) Infection in Elementary School Students in the River Banks Area, South Kalimantan, Indonesia
    Jujuk Anton Cahyono, Rifqoh, Yayuk Kustiningsih, Ahmad Muhlisin
    Journal of Law and Sustainable Development.2023; 11(11): e1375.     CrossRef
  • Assessment of Rare Case on Patient with Filariasis-Associated Bilateral Pleural Effusion
    Astuti Arseda, Dikes Simanjuntak, Tuti Pahria, Urip Rahayu, Nursiswati Nursiswati
    Malaysian Journal of Medicine and Health Sciences.2023; 19(6): 364.     CrossRef
  • Vector Surveillance for Lymphatic Filariasis After Mass Drug Administration in an Endemic Area: A Case Study in Bekasi
    Endang Puji Astuti, Joni Hendri, Mara Ipa, Andri Ruliansyah, Triwibowo Ambar Garjito
    JURNAL KESEHATAN LINGKUNGAN .2023; 15(2): 134.     CrossRef
  • An inventory of human night-biting mosquitoes and their bionomics in Sumba, Indonesia
    Lepa Syahrani, Dendi H. Permana, Din Syafruddin, Siti Zubaidah, Puji B. S. Asih, Ismail E. Rozi, Anggi P. N. Hidayati, Sully Kosasih, Farahana K. Dewayanti, Nia Rachmawati, Rifqi Risandi, Michael J. Bangs, Claus Bøgh, Jenna Davidson, Allison Hendershot, T
    PLOS Neglected Tropical Diseases.2022; 16(3): e0010316.     CrossRef
  • Tracking the molecular evolution and transmission patterns of SARS-CoV-2 lineage B.1.466.2 in Indonesia based on genomic surveillance data
    Mingjian Zhu, Qianli Zeng, Bryanna Infinita Laviashna Saputro, Sien Ping Chew, Ian Chew, Holie Frendy, Joanna Weihui Tan, Lanjuan Li
    Virology Journal.2022;[Epub]     CrossRef
  • Short-, Mid-, and Long-Term Epidemiological and Economic Effects of the World Bank Loan Project on Schistosomiasis Control in the People’s Republic of China
    Qin Li, Jing Xu, Shi-Zhu Li, Jürg Utzinger, Donald P. McManus, Xiao-Nong Zhou
    Diseases.2022; 10(4): 84.     CrossRef
  • Personal Hygiene and Soil Transmitted Helminth Incidence in Elementary School Students Amanuban Barat District, South Central Timor
    Michael Bhadi Bia, Ni Made Susilawati, Agnes Rantesalu, Karol Octrisdey, Winioliski L.O. Rohi Bire
    JURNAL INFO KESEHATAN.2022; 20(2): 260.     CrossRef
  • Lymphatic filariasis in Asia: a systematic review and meta-analysis
    Negar Bizhani, Saeideh Hashemi Hafshejani, Neda Mohammadi, Mehdi Rezaei, Mohammad Bagher Rokni
    Parasitology Research.2021; 120(2): 411.     CrossRef
  • Soil-transmitted helminth infection, anemia, and malnutrition among preschool-age children in Nangapanda subdistrict, Indonesia
    Yenny Djuardi, Gilbert Lazarus, Difa Stefanie, Umi Fahmida, Iwan Ariawan, Taniawati Supali, Maria Angeles Gómez-Morales
    PLOS Neglected Tropical Diseases.2021; 15(6): e0009506.     CrossRef
  • The Prevalence of Intestinal Protozoan Infections among Children in Southwest Sumba Based on the Type of Water Sources
    Sri Wahdini, Vicco Primadhasta Putra, Saleha Sungkar
    Infection & Chemotherapy.2021; 53(3): 519.     CrossRef
  • DNA of Brugia malayi detected in several mosquito species collected from Balangan District, South Borneo Province, Indonesia
    Supriyono Supriyono, Suriyani Tan
    Veterinary World.2020; 13(5): 996.     CrossRef
  • 14,981 View
  • 392 Download
  • 20 Web of Science
  • Crossref

Original Articles

Antifilarial and Antibiotic Activities of Methanolic Extracts of Melaleuca cajuputi Flowers
Nazeh M. Al-Abd, Zurainee Mohamed Nor, Marzida Mansor Hasan, Mustafa Kassim
Korean J Parasitol 2016;54(3):273-280.
Published online June 30, 2016
DOI: https://doi.org/10.3347/kjp.2016.54.3.273
We evaluated the activity of methanolic extracts of Melaleuca cajuputi flowers against the filarial worm Brugia pahangi and its bacterial endosymbiont Wolbachia. Anti-Wolbachia activity was measured in worms and in Aedes albopictus Aa23 cells by PCR, electron microscopy, and other biological assays. In particular, microfilarial release, worm motility, and viability were determined. M. cajuputi flower extracts were found to significantly reduce Wolbachia endosymbionts in Aa23 cells, Wolbachia surface protein, and microfilarial release, as well as the viability and motility of adult worms. Anti-Wolbachia activity was further confirmed by observation of degraded and phagocytized Wolbachia in worms treated with the flower extracts. The data provided in vitro and in vivo evidence that M. cajuputi flower extracts inhibit Wolbachia, an activity that may be exploited as an alternative strategy to treat human lymphatic filariasis.

Citations

Citations to this article as recorded by  Crossref logo
  • Two decades of antifilarial drug discovery: a review
    Jaiprakash N. Sangshetti, Devanand B. Shinde, Abhishek Kulkarni, Rohidas Arote
    RSC Advances.2017; 7(33): 20628.     CrossRef
  • 9,481 View
  • 153 Download
  • 5 Web of Science
  • Crossref
Finding Wolbachia in Filarial larvae and Culicidae Mosquitoes in Upper Egypt Governorate
Ahmed K. Dyab, Lamia A. Galal, Abeer E. Mahmoud, Yasser Mokhtar
Korean J Parasitol 2016;54(3):265-272.
Published online June 30, 2016
DOI: https://doi.org/10.3347/kjp.2016.54.3.265
Wolbachia is an obligatory intracellular endosymbiotic bacterium, present in over 20% of all insects altering insect reproductive capabilities and in a wide range of filarial worms which is essential for worm survival and reproduction. In Egypt, no available data were found about Wolbachia searching for it in either mosquitoes or filarial worms. Thus, we aimed to identify the possible concurrent presence of Wolbachia within different mosquitoes and filarial parasites, in Assiut Governorate, Egypt using multiplex PCR. Initially, 6 pools were detected positive for Wolbachia by single PCR. The simultaneous detection of Wolbachia and filarial parasites (Wuchereria bancrofti, Dirofilaria immitis, and Dirofilaria repens) by multiplex PCR was spotted in 5 out of 6 pools, with an overall estimated rate of infection (ERI) of 0.24%. Unexpectedly, the highest ERI (0.53%) was for Anopheles pharoensis with related Wolbachia and W. bancrofti, followed by Aedes (0.42%) and Culex (0.26%). We also observed that Wolbachia altered Culex spp. as a primary vector for W. bancrofti to be replaced by Anopheles sp. Wolbachia within filaria-infected mosquitoes in our locality gives a hope to use bacteria as a new control trend simultaneously targeting the vector and filarial parasites.

Citations

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  • Distinct microbial communities of drain flies (Clogmia albipunctata) across sites with differing human influence
    Hyun Seo Park, Xavier Chavarria, Arwa Shatta, Dongjun Kang, Singeun Oh, Du-Yeol Choi, Jun Ho Choi, Myungjun Kim, Yoon Hee Cho, Myung-hee Yi, Ju Yeong Kim
    FEMS Microbiology Letters.2025;[Epub]     CrossRef
  • Mitochondrial and microbial diversity of the invasive mosquito vector species Culex tritaeniorhynchus across its extensive inter-continental geographic range
    Claire L. Jeffries, Luciano M Tantely, Perparim Kadriaj, Marcus S C Blagrove, Ioanna Lytra, James Orsborne, Hasan Mohammad Al-Amin, Abdul Rahim Mohammed, Mohammad Shafiul Alam, Romain Girod, Yaw A Afrane, Silvia Bino, Vincent Robert, Sebastien Boyer, Matt
    Wellcome Open Research.2024; 9: 18.     CrossRef
  • Culex-Transmitted Diseases: Mechanisms, Impact, and Future Control Strategies using Wolbachia
    Mukund Madhav, Kim R. Blasdell, Brendan Trewin, Prasad N. Paradkar, Adam J. López-Denman
    Viruses.2024; 16(7): 1134.     CrossRef
  • Mosquito Vectors (Diptera: Culicidae) and Mosquito-Borne Diseases in North Africa
    Amira Nebbak, Lionel Almeras, Philippe Parola, Idir Bitam
    Insects.2022; 13(10): 962.     CrossRef
  • Larvicidal and repellent potential of Ageratum houstonianum against Culex pipiens
    Doaa El Hadidy, Abeer M. El Sayed, Mona El Tantawy, Taha El Alfy, Shaimaa M. Farag, Doaa R. Abdel Haleem
    Scientific Reports.2022;[Epub]     CrossRef
  • Wolbachia infection in West Nile Virus vectors of northwest Iran
    Faramarz Bozorg-Omid, Mohammad Ali Oshaghi, Mozaffar Vahedi, Fateh Karimian, Seyyed Javad Seyyed-Zadeh, Ali Reza Chavshin
    Applied Entomology and Zoology.2020; 55(1): 105.     CrossRef
  • Dirofilaria and Wolbachia in mosquitoes (Diptera: Culicidae) in central European Russia and on the Black Sea coast
    Elena Shaikevich, Anna Bogacheva, Ludmila Ganushkina
    Parasite.2019; 26: 2.     CrossRef
  • 11,457 View
  • 153 Download
  • 8 Web of Science
  • Crossref

Case Report

A Rare Human Case of Dirofilaria repens Infection in the Subcutaneous Posterior Thorax with Molecular Identification
Tran Anh Le, Thuat Thang Vi, Khac Luc Nguyen, Thanh Hoa Le
Korean J Parasitol 2015;53(3):329-333.
Published online June 30, 2015
DOI: https://doi.org/10.3347/kjp.2015.53.3.329
The emergence of dirofilarial infections in Asia including Vietnam is a clinically significant threat to the community. We here report a rare case of subcutaneous Dirofilaria repens infection on the posterior thoracic wall in a young woman presenting a painful, itchy, and palpable nodule. The adult worm was identified by mitochondrial cox1 and nuclear ITS-2 sequence determination. The diagnosis was additionally confirmed by 16S rRNA sequencing of the endosymbiont Wolbachia pipientis commonly co-existing with D. repens. This is a rare case of subcutaneous human infection on the posterior thoracic region caused by D. repens.

Citations

Citations to this article as recorded by  Crossref logo
  • Human dirofilariasis – A potentially significant nematode zoonosis in an era of climate change
    Stefan Momčilović, Andriana Jovanović, Robin B. Gasser
    Journal of Infection.2025; 90(4): 106460.     CrossRef
  • Two cases of ectopic dirofilariasis by Dirofilaria immitis in subconjunctival and subcutaneous tissues in dogs
    Yeong-Seok Goh, Hye-Min Kim, Badriah Alkathiri, Hong Suh Chang, Young Min Yoon, Seung-Hun Lee, Kyung-Mee Park
    Parasitology International.2023; 92: 102683.     CrossRef
  • Genetic and geographical delineation of zoonotic vector-borne helminths of canids
    Younes Laidoudi, Samia Bedjaoui, Maria Stefania Latrofa, Angela Fanelli, Filipe Dantas-Torres, Domenico Otranto
    Scientific Reports.2022;[Epub]     CrossRef
  • Canine and feline vector-borne diseases of zoonotic concern in Southeast Asia
    Viet-Linh Nguyen, Filipe Dantas-Torres, Domenico Otranto
    Current Research in Parasitology & Vector-Borne Diseases.2021; 1: 100001.     CrossRef
  • The Complexity of Zoonotic Filariasis Episystem and Its Consequences: A Multidisciplinary View
    Fernando Simón, Javier González-Miguel, Alicia Diosdado, Paula Josefina Gómez, Rodrigo Morchón, Vladimir Kartashev
    BioMed Research International.2017; 2017: 1.     CrossRef
  • Molecular characterization of human Dirofilaria isolates from Kerala
    Najuma Nazar, Bindu Lakshmanan, K.K. Jayavardhanan
    Indian Journal of Medical Research.2017; 146(4): 528.     CrossRef
  • The Mitochondrial Genomes of the Zoonotic Canine Filarial Parasites Dirofilaria (Nochtiella) repens and Candidatus Dirofilaria (Nochtiella) Honkongensis Provide Evidence for Presence of Cryptic Species
    Esra Yilmaz, Moritz Fritzenwanker, Nikola Pantchev, Mathias Lendner, Sirichit Wongkamchai, Domenico Otranto, Inge Kroidl, Martin Dennebaum, Thanh Hoa Le, Tran Anh Le, Sabrina Ramünke, Roland Schaper, Georg von Samson-Himmelstjerna, Sven Poppert, Jürgen Kr
    PLOS Neglected Tropical Diseases.2016; 10(10): e0005028.     CrossRef
  • Development and Application of a Loop-Mediated Isothermal Amplification (LAMP) Approach for the Rapid Detection of Dirofilaria repens from Biological Samples
    Donato Antonio Raele, Nicola Pugliese, Domenico Galante, Laura Maria Latorre, Maria Assunta Cafiero, John Pius Dalton
    PLOS Neglected Tropical Diseases.2016; 10(6): e0004789.     CrossRef
  • 10,448 View
  • 114 Download
  • 9 Web of Science
  • Crossref

Original Article

Xenomonitoring of Different Filarial Nematodes Using Single and Multiplex PCR in Mosquitoes from Assiut Governorate, Egypt
Ahmed Kamal Dyab, Lamia Ahmed Galal, Abeer El-Sayed Mahmoud, Yasser Mokhtar
Korean J Parasitol 2015;53(1):77-83.
Published online February 27, 2015
DOI: https://doi.org/10.3347/kjp.2015.53.1.77

Dirofilaria immitis, Dirofilaria immitis, and Dirofilaria repens are filarial nematodes transmitted by mosquitoes belonging to Culex, Aedes, and Anopheles genera. Screening by vector dissection is a tiresome technique. We aimed to screen filarial parasites in their vectors by single and multiplex PCR and evaluate the usefulness of multiplex PCR as a rapid xenomonitoring and simultaneous differentiation tool, in area where 3 filarial parasites are coexisting. Female mosquitoes were collected from 7 localities in Assiut Governorate, were microscopically identified and divided into pools according to their species and collection site. Detection of W. bancrofti, D. immitis, and D. repens using single PCR was reached followed by multiplex PCR. Usefulness of multiplex PCR was evaluated by testing mosquito pools to know which genera and species are used by filarial parasites as a vector. An overall estimated rate of infection (ERI) in mosquitoes was 0.6%; the highest was Culex spp. (0.47%). W. bancrofti, D. immitis, and D. repens could be simultaneously and differentially detected in infected vectors by using multiplex PCR. Out of 100 mosquito pools, 8 were positive for W. bancrofti (ERI of 0.33%) and 3 pools each were positive for D. immitis and D. repens (ERI 0.12%). The technique showed 100% sensitivity and 98% specificity. El-Nikhila, El-Matiaa villages, and Sahel Seleem district in Assiut Governorate, Egypt are still endemic foci for filarial parasites. Multiplex PCR offers a reliable procedure for molecular xenomonitoring of filariasis within their respective vectors in endemic areas. Therefore, it is recommended for evaluation of mosquito infection after lymphatic filariasis eradication programs.

Citations

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  • Current Gaps in Survey Design and Analysis for Molecular Xenomonitoring of Vector‐Borne Neglected Tropical Diseases: A Systematic Review
    Angus McLure, Tilahun Alamnia, Zhiwei Xu, Colleen L. Lau, Helen J. Mayfield
    Tropical Medicine & International Health.2025; 30(9): 893.     CrossRef
  • Synthesis, larvicidal efficiency and molecular docking studies of novel annulated pyrano[2,3-c]pyrazoles against Culex pipiens L. and Musca domestica L. larvae
    Mahmoud K.F. El-Sayed, Manal M. El-Shahawi, Yasmeen M. Ali, Doaa R. Abdel-Haleem, Fatma S.M. Abu El-Azm
    Bioorganic Chemistry.2023; 130: 106258.     CrossRef
  • Mosquito Vectors (Diptera: Culicidae) and Mosquito-Borne Diseases in North Africa
    Amira Nebbak, Lionel Almeras, Philippe Parola, Idir Bitam
    Insects.2022; 13(10): 962.     CrossRef
  • The use of molecular xenomonitoring for surveillance of mosquito-borne diseases
    Mary M. Cameron, Anita Ramesh
    Philosophical Transactions of the Royal Society B: Biological Sciences.2021; 376(1818): 20190816.     CrossRef
  • Bancroftian Filariasis Still Endemic in Some Foci in Sohag Governorate, Upper Egypt
    Refaat MA Khalifa, Amal M Ahmed, Mohamed AA Taha, Nasr Eldeen MM Ali, Haitham KA Abd El Samea, Dabbu Jaijyan
    Journal of Parasite Research.2019; 1(1): 1.     CrossRef
  • Comparative evaluation of dry and liquid RIME LAMP in detecting trypanosomes in dead tsetse flies
    Peter Nambala, Janelisa Musaya, Kyoko Hayashida, Emmanuel Maganga, Edward Senga, Kelita Kamoto, John Chisi, Chihiro Sugimoto
    Onderstepoort Journal of Veterinary Research.2018;[Epub]     CrossRef
  • Implementing a community vector collection strategy using xenomonitoring for the endgame of lymphatic filariasis elimination
    Sellase Pi-Bansa, Joseph Harold Nyarko Osei, Joannitta Joannides, Maame Esi Woode, David Agyemang, Elizabeth Elhassan, Samuel Kweku Dadzie, Maxwell Alexander Appawu, Michael David Wilson, Benjamin Guibehi Koudou, Dziedzom Komi de Souza, Jürg Utzinger, Dan
    Parasites & Vectors.2018;[Epub]     CrossRef
  • Finding Wolbachia in Filarial larvae and Culicidae Mosquitoes in Upper Egypt Governorate
    Ahmed K. Dyab, Lamia A. Galal, Abeer E. Mahmoud, Yasser Mokhtar
    The Korean Journal of Parasitology.2016; 54(3): 265.     CrossRef
  • Trypanosome infection rates in tsetse flies in the “silent” sleeping sickness focus of Bafia in the Centre Region in Cameroon
    Gustave Simo, Pierre Fongho, Oumarou Farikou, Prosper Innocent Ndjeuto Ndjeuto-Tchouli, Judith Tchouomene-Labou, Flobert Njiokou, Tazoacha Asonganyi
    Parasites & Vectors.2015;[Epub]     CrossRef
  • 10,849 View
  • 163 Download
  • 13 Web of Science
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Brief Communication

Prevalence of Dirofilaria immitis Infection in Stray Cats by Nested PCR in Korea
Hyung-Jin Park, Sang-Eun Lee, Won-Ja Lee, Jung-Hyun Oh, Easwaran Maheswaran, Kyoung-Won Seo, Kun-Ho Song
Korean J Parasitol 2014;52(6):691-694.
Published online December 23, 2014
DOI: https://doi.org/10.3347/kjp.2014.52.6.691

The purpose of this study was to conduct a survey of Dirofilaria immitis infection among stray cats in Korea using nested PCR. We included 235 stray cats (121 females and 114 males) and evaluated each for the presence of feline heartworm infection. Blood samples were collected from 135 cats in Daejeon, 50 cats in Seoul, and 50 cats from Gyeonggi-do (Province). Of the 235 DNA samples, 14 (6.0%) were positive for D. immitis. The prevalence of infection in male cats (8/114, 7.0%) tended to be higher than that in female cats (6/121, 5.0%), but the difference was not statistically significant. In each location, 8, 2, and 4 cats were positive for infection, respectively, based on DNA testing. No significant differences in the prevalence were observed among the geographic regions, although the rate of infection was higher in Gyeonggi-do (8.0%) than Daejeon (5.9%) and Seoul (4.0%). We submitted 7 of the 14 D. immitis DNA-positive samples for sequencing analysis. All samples corresponded to partial D. immitis cytochrome c oxidase subunit I gene sequences with 99% homology to the D. immitis sequence deposited in GenBank (accession no. FN391553). To the best of our knowledge, this is the first survey using nested PCR to analyze the prevalence of D. immitis in stray cats in Korea.

Citations

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  • Status of selected feline infectious diseases in Gwangju, Korea
    Juyeon Choi, Kyu-Sung Ahn, Ah-Jin Ahn, SungShik Shin
    Korean Journal of Veterinary Research.2023; 63(4): e31.     CrossRef
  • Evidence of Dirofilaria immitis in Felids in North-Eastern Italy
    Marika Grillini, Antonio Frangipane di Regalbono, Cinzia Tessarin, Paola Beraldo, Rudi Cassini, Erica Marchiori, Giulia Simonato
    Pathogens.2022; 11(10): 1216.     CrossRef
  • Prevalence of infection with Dirofilaria immitis in cats in Townsville, Australia
    Carl Adagra, Richard Squires, Angela Adagra, Jennifer Elliman, Constantin Constantinoiu
    Veterinary Parasitology: Regional Studies and Reports.2021; 24: 100580.     CrossRef
  • Seroprevalence of Dirofilaria immitis in Cats from Liaoning Province, Northeastern China
    Honglie Hou, Lili Cao, Wenzhi Ren, Dansheng Wang, He Ding, Juan You, Xinhua Yao, Hang Dong, Yanbing Guo, Shuxian Yuan, Xichen Zhang, Pengtao Gong
    The Korean Journal of Parasitology.2017; 55(6): 673.     CrossRef
  • Toxoplasma gondii, Dirofilaria immitis, feline immunodeficiency virus (FIV), and feline leukemia virus (FeLV) infections in stray and pet cats (Felis catus) in northwest China: co-infections and risk factors
    Wei Cong, Qing-Feng Meng, Radu Blaga, Isabelle Villena, Xing-Quan Zhu, Ai-Dong Qian
    Parasitology Research.2016; 115(1): 217.     CrossRef
  • 11,325 View
  • 104 Download
  • 6 Web of Science
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Original Articles

Expression of Translationally Controlled Tumor Protein (TCTP) Gene of Dirofilaria immitis Guided by Transcriptomic Screening
Yan Fu, Jingchao Lan, Xuhang Wu, Deying Yang, Zhihe Zhang, Huaming Nie, Rong Hou, Runhui Zhang, Wanpeng Zheng, Yue Xie, Ning Yan, Zhi Yang, Chengdong Wang, Li Luo, Li Liu, Xiaobin Gu, Shuxian Wang, Xuerong Peng, Guangyou Yang
Korean J Parasitol 2014;52(1):21-26.
Published online February 19, 2014
DOI: https://doi.org/10.3347/kjp.2014.52.1.21

Dirofilaria immitis (heartworm) infections affect domestic dogs, cats, and various wild mammals with increasing incidence in temperate and tropical areas. More sensitive antibody detection methodologies are required to diagnose asymptomatic dirofilariasis with low worm burdens. Applying current transcriptomic technologies would be useful to discover potential diagnostic markers for D. immitis infection. A filarial homologue of the mammalian translationally controlled tumor protein (TCTP) was initially identified by screening the assembled transcriptome of D. immitis (DiTCTP). A BLAST analysis suggested that the DiTCTP gene shared the highest similarity with TCTP from Loa loa at protein level (97%). A histidine-tagged recombinant DiTCTP protein (rDiTCTP) of 40 kDa expressed in Escherichia coli BL21 (DE3) showed immunoreactivity with serum from a dog experimentally infected with heartworms. Localization studies illustrated the ubiquitous presence of rDiTCTP protein in the lateral hypodermal chords, dorsal hypodermal chord, muscle, intestine, and uterus in female adult worms. Further studies on D. immitis-derived TCTP are warranted to assess whether this filarial protein could be used for a diagnostic purpose.

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  • Molecular Discovery of Filarial Nematode DNA in an Endangered Wild Pinniped (Galapagos Sea Lion, Zalophus wollebaeki)
    Isabella G. Livingston, Taylor M. Gregory, Eleanor C. Hawkins, Ashley Cave, Andrea Loyola, Shelly L. Vaden, Diane Deresienski, Marjorie Riofrío‐Lazo, Gregory A. Lewbart, Diego Páez‐Rosas, Matthew Breen
    Ecology and Evolution.2024;[Epub]     CrossRef
  • Development of TaqMan Quantitative PCR Assays for Duplex Detection of Dirofilaria immitis COI and Dog GAPDH from Infected Dog Blood
    In Young Oh, Kyung Tae Kim, Sun-Yeong Gwon, Ho Joong Sung
    The Korean Journal of Clinical Laboratory Science.2019; 51(1): 64.     CrossRef
  • Brown Spider (Loxosceles) Venom Toxins as Potential Biotools for the Development of Novel Therapeutics
    Daniele Chaves-Moreira, Fernando Hitomi Matsubara, Zelinda Schemczssen-Graeff, Elidiana De Bona, Vanessa Ribeiro Heidemann, Clara Guerra-Duarte, Luiza Helena Gremski, Carlos Chávez-Olórtegui, Andrea Senff-Ribeiro, Olga Meiri Chaim, Raghuvir Krishnaswamy A
    Toxins.2019; 11(6): 355.     CrossRef
  • Development of Real-time PCR Assays for Detection ofDirofilaria immitisfrom Infected Dog Blood
    In Young Oh, Kyung Tae Kim, Jin Hyun Jun, Jae-Ho Shin, Ho Joong Sung
    Korean Journal of Clinical Laboratory Science.2016; 48(2): 88.     CrossRef
  • 9,413 View
  • 84 Download
  • 3 Web of Science
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Rapid Detection and Identification of Wuchereria bancrofti, Brugia malayi, B. pahangi, and Dirofilaria immitis in Mosquito Vectors and Blood Samples by High Resolution Melting Real-Time P
Tongjit Thanchomnang, Pewpan M. Intapan, Chairat Tantrawatpan, Viraphong Lulitanond, Sudchit Chungpivat, Piyanan Taweethavonsawat, Worasak Kaewkong, Oranuch Sanpool, Penchom Janwan, Wej Choochote, Wanchai Maleewong
Korean J Parasitol 2013;51(6):645-650.
Published online December 31, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.6.645

A simple, rapid, and high-throughput method for detection and identification of Wuchereria bancrofti, Brugia malayi, Brugia pahangi, and Dirofilaria immitis in mosquito vectors and blood samples was developed using a real-time PCR combined with high-resolution melting (HRM) analysis. Amplicons of the 4 filarial species were generated from 5S rRNA and spliced leader sequences by the real-time PCR and their melting temperatures were determined by the HRM method. Melting of amplicons from W. bancrofti, B. malayi, D. immitis, and B. pahangi peaked at 81.5±0.2℃, 79.0±0.3℃, 76.8±0.1℃, and 79.9±0.1℃, respectively. This assay is relatively cheap since it does not require synthesis of hybridization probes. Its sensitivity and specificity were 100%. It is a rapid and technically simple approach, and an important tool for population surveys as well as molecular xenomonitoring of parasites in vectors.

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  • Beyond Tradition: Exploring Cutting-Edge Approaches for Accurate Diagnosis of Human Filariasis
    Damian Pietrzak, Julia Weronika Łuczak, Marcin Wiśniewski
    Pathogens.2024; 13(6): 447.     CrossRef
  • Detecting Dirofilaria immitis: Current Practices and Novel Diagnostic Methods
    Damian Pietrzak, Julia Weronika Łuczak, Marcin Wiśniewski
    Pathogens.2024; 13(11): 950.     CrossRef
  • IDENTIFICATION OF MICROFILARIAE USING CONVENTIONAL POLYMERASE CHAIN REACTION AND QPCR-HRM
    Bagus Muhammad Ihsan, Widyana Lakshmi Puspita, Linda Triana, Wahdaniah, Khayan, Cecep Dani Sucipto
    Journal of Vocational Health Studies.2024; 8(1): 42.     CrossRef
  • Mosquitoes, Lymphatic Filariasis, and Public Health: A Systematic Review of Anopheles and Aedes Surveillance Strategies
    Arumugam Bhuvaneswari, Ananganallur Nagarajan Shriram, Kishan Hari K. Raju, Ashwani Kumar
    Pathogens.2023; 12(12): 1406.     CrossRef
  • Microfilaria Positification Test Using Real-Time PCR Technique with HRM (High-Resolution Melting)
    Bagus Muhammad Ihsan, Afiat Berbudi, Ridad Agoes, Muhammad Ifham Hanif
    Acta Parasitologica.2022; 67(1): 496.     CrossRef
  • Collection and DNA Detection of Dirofilaria immitis (Rhabditida Onchocercidae), Using a Novel Primer Set, in Wild-Caught Mosquitoes From Gainesville, FL
    Chris Holderman, Nicole O Abruzzo, Noor A Abdelsamad, Phillip E Kaufman, Peter M DiGennaro, Stephen Rich
    Journal of Medical Entomology.2021; 58(3): 1429.     CrossRef
  • The use of molecular xenomonitoring for surveillance of mosquito-borne diseases
    Mary M. Cameron, Anita Ramesh
    Philosophical Transactions of the Royal Society B: Biological Sciences.2021; 376(1818): 20190816.     CrossRef
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    Viet-Linh Nguyen, Filipe Dantas-Torres, Domenico Otranto
    Current Research in Parasitology & Vector-Borne Diseases.2021; 1: 100001.     CrossRef
  • The Incidence of Dirofilaria immitis in Shelter Dogs and Mosquitoes in Austria
    Karin Sonnberger, Hans-Peter Fuehrer, Bernhard Werner Sonnberger, Michael Leschnik
    Pathogens.2021; 10(5): 550.     CrossRef
  • Membrane Technology for Rapid Point-of-Care Diagnostics for Parasitic Neglected Tropical Diseases
    Madeleine J. Rogers, Donald P. McManus, Stephen Muhi, Catherine A. Gordon
    Clinical Microbiology Reviews.2021;[Epub]     CrossRef
  • PRIMARY SLX TEST USING REAL-TIME PCR BASED ON HIGH RESOLUTION MELTING (HRM) ON MICROFILARIA EXAMINATION
    Bagus Muhammad Ihsan, Cecep Dani Sucipto, Khayan Khayan
    Journal of Vocational Health Studies.2021; 5(1): 26.     CrossRef
  • Molecular detection of Trichostrongylus species through PCR followed by high resolution melt analysis of ITS-2 rDNA sequences
    Mohsen Arbabi, Hossein Hooshyar, Majid Lotfinia, Mohamad Ali Bakhshi
    Molecular and Biochemical Parasitology.2020; 236: 111260.     CrossRef
  • Prevalence and risk factors associated with Dirofilaria immitis infection in dogs and cats in Songkhla and Satun provinces, Thailand
    Ketsarin Kamyingkird, Witchuta Junsiri, Witsanuwat Chimnoi, Chanya Kengradomkij, Sinsamut Saengow, Keplee Sangchuto, Wicha Kajeerum, Decha Pangjai, Burin Nimsuphan, Tawin Inpankeaw, Sathaporn Jittapalapong
    Agriculture and Natural Resources.2017; 51(4): 299.     CrossRef
  • Is molecular xenomonitoring of mosquitoes for Dirofilaria repens suitable for dirofilariosis surveillance in endemic regions?
    Aleksander Masny, Rusłan Sałamatin, Wioletta Rozej-Bielicka, Elzbieta Golab
    Parasitology Research.2016; 115(2): 511.     CrossRef
  • Pyrosequencing Using SL and 5S rRNA as Molecular Markers for Identifying Zoonotic Filarial Nematodes in Blood Samples and Mosquitoes
    Oranuch Sanpool, Chairat Tantrawatpan, Tongjit Thanchomnang, Penchom Janwan, Pewpan M. Intapan, Rutchanee Rodpai, Viraphong Lulitanond, Piyanan Taweethavonsawat, Wanchai Maleewong
    Vector-Borne and Zoonotic Diseases.2016; 16(5): 326.     CrossRef
  • Detection and quantification of Wuchereria bancrofti and Brugia malayi DNA in blood samples and mosquitoes using duplex droplet digital polymerase chain reaction
    Jurairat Jongthawin, Pewpan M. Intapan, Viraphong Lulitanond, Oranuch Sanpool, Tongjit Thanchomnang, Lakkhana Sadaow, Wanchai Maleewong
    Parasitology Research.2016; 115(8): 2967.     CrossRef
  • Trypanosome infection rates in tsetse flies in the “silent” sleeping sickness focus of Bafia in the Centre Region in Cameroon
    Gustave Simo, Pierre Fongho, Oumarou Farikou, Prosper Innocent Ndjeuto Ndjeuto-Tchouli, Judith Tchouomene-Labou, Flobert Njiokou, Tazoacha Asonganyi
    Parasites & Vectors.2015;[Epub]     CrossRef
  • 11,673 View
  • 134 Download
  • Crossref

Case Report

A Case of Human Pulmonary Dirofilariasis in a 48-Year-Old Korean Man
Hyo Jae Kang, Young Sik Park, Chang-Hoon Lee, Sang-Min Lee, Jae-Joon Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Jong-Yil Chai, Jinwoo Lee
Korean J Parasitol 2013;51(5):569-572.
Published online October 31, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.5.569

Dirofilariasis is a rare disease in humans. We report here a case of a 48-year-old male who was diagnosed with pulmonary dirofilariasis in Korea. On chest radiographs, a coin lesion of 1 cm in diameter was shown. Although it looked like a benign inflammatory nodule, malignancy could not be excluded. So, the nodule was resected by video-assisted thoracic surgery. Pathologically, chronic granulomatous inflammation composed of coagulation necrosis with rim of fibrous tissues and granulations was seen. In the center of the necrotic nodules, a degenerating parasitic organism was found. The parasite had prominent internal cuticular ridges and thick cuticle, a well-developed muscle layer, an intestinal tube, and uterine tubules. The parasite was diagnosed as an immature female worm of Dirofilaria immitis. This is the second reported case of human pulmonary dirofilariasis in Korea.

Citations

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  • Human Pulmonary Dirofilariasis: A Review for the Clinicians
    Biplab K Saha, Alyssa Bonnier, Woon Hean Chong, Hau Chieng, Adam Austin, Kurt Hu, Boris Shkolnik
    The American Journal of the Medical Sciences.2022; 363(1): 11.     CrossRef
  • 62-year-old woman with PET-positive solitary pulmonary nodule
    Biplab Saha, Woon Hean Chong, Hau Chieng, Amit Chopra
    BMJ Case Reports.2021; 14(6): e243695.     CrossRef
  • Man's best friend: How humans can develop Dirofilaria immitis infections
    Devin Malik, Akshay Amaraneni, Sukhpreet Singh, Richard Roach
    IDCases.2016; 4: 43.     CrossRef
  • A 72-Year-Old Woman With Previous Pulmonary Metastasis and New Peripheral Nodule
    Giovanni Maria Comacchio, Chiara Giraudo, Nazarena Nannini, Alessandro Rebusso, Roberta Polverosi, Federico Rea, Fiorella Calabrese
    Chest.2015; 148(2): e42.     CrossRef
  • Investigation of Dirofilaria immitis infection in stray dogs from public animal shelters in Seoul
    Neung-Hee Kim, Jeong-Yeon Kwak, Hye-Ra Kim, Hyeong-Suk Park, Doo-Hwan Kim, Ju-Hyung Lee
    Korean Journal of Veterinary Service.2014; 37(3): 197.     CrossRef
  • Orbital Dirofilariasis
    Se Hyun Choi, Namju Kim, Jin Ho Paik, Jaeeun Cho, Jong-Yil Chai
    Korean Journal of Ophthalmology.2014; 28(6): 495.     CrossRef
  • 9,884 View
  • 91 Download
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Brief Communication

Prevalence of Dirofilaria immitis in Dogs in Shenyang, Northeastern China
Chengwu Liu, Na Yang, Jianbin He, Min Yang, Ming Sun
Korean J Parasitol 2013;51(3):375-377.
Published online June 30, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.3.375

In the present study, we first report the seroprevalence of Dirofilaria immitis in dogs in Shenyang, northeastern China. Sera from 528 randomly selected dogs were examined for D. immitis antigen using SNAP®4Dx test kit; 12.7% tested showed seropositive. No significant difference of infection was observed in different genders and breeds (P>0.05), but the difference was significant in different age groups and rearing conditions (P<0.05). The result suggested that the risk of exposure to D. immitis in dogs is high in Shenyang, and should be given attention.

Citations

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  • The seroprevalence of canine dirofilariosis in dogs in the eastern coastal areas of China
    Dongjie Cai, Bin Tian, Yongxia Liu, Mujeeb Ur Rehman, David Ranucci, Fabrizia Veronesi, Antonio Varcasia, Wanzhong Jia, Jianzhu Liu
    Heliyon.2023; 9(6): e17009.     CrossRef
  • The prevalence of canine dirofilariasis in China: a systematic review and meta-analysis
    Zhu Ying, Archana Upadhyay, Jinhua Wang, Qian Han, Qun Liu
    Parasites & Vectors.2023;[Epub]     CrossRef
  • Prevalence and molecular characterization of Dirofilaria immitis in road killed canids of northern Iran
    Meysam Sharifdini, Mahan Karimi, Keyhan Ashrafi, Mostafa Soleimani, Hamed Mirjalali
    BMC Veterinary Research.2022;[Epub]     CrossRef
  • Heartworm disease – Overview, intervention, and industry perspective
    Sandra Noack, John Harrington, Douglas S. Carithers, Ronald Kaminsky, Paul M. Selzer
    International Journal for Parasitology: Drugs and Drug Resistance.2021; 16: 65.     CrossRef
  • The prevalence of Dirofilaria immitis and D. repens in the Old World
    Claudio Genchi, Laura Helen Kramer
    Veterinary Parasitology.2020; 280: 108995.     CrossRef
  • The global status of Dirofilaria immitis in dogs: a systematic review and meta-analysis based on published articles
    Davood Anvari, Elahe Narouei, Ahmad Daryani, Shahabeddin Sarvi, Mahmood Moosazadeh, Hajar Ziaei Hezarjaribi, Mohammad Reza Narouei, Shirzad Gholami
    Research in Veterinary Science.2020; 131: 104.     CrossRef
  • Filarial worms: a systematic review and meta-analysis of diversity in animals from Iran with emphasis on human cases
    Ezatollah Ghasemi, Sadegh Shamsinia, Ali Taghipour, Davood Anvari, Saeed Bahadory, Seyyed Ali Shariatzadeh, Bahareh Kordi, Hamidreza Majidiani, Hassan Borji, MohammadReza Chaechi Nosrati, Ali Yousefi, Morteza Shams
    Parasitology.2020; 147(9): 909.     CrossRef
  • Detection of Dirofilaria immitis antigen and antibodies against Anaplasma phagocytophilum, Borrelia burgdorferi and Ehrlichia canis in dogs from ten provinces of China
    Jiawei Wang, Patrick Kelly, Jilei Zhang, Zhengsheng Shi, Chunlian Song, Xiaofeng Zheng, Yi Zhang, Yongqing Hao, Haiju Dong, Heba S. El-Mahallawy, Wenbin Xiong, Heng Wang, Jianji Li, Xinjun Zhang, Chengming Wang
    Acta Parasitologica.2018; 63(2): 412.     CrossRef
  • Seroprevalence of Dirofilaria immitis in Cats from Liaoning Province, Northeastern China
    Honglie Hou, Lili Cao, Wenzhi Ren, Dansheng Wang, He Ding, Juan You, Xinhua Yao, Hang Dong, Yanbing Guo, Shuxian Yuan, Xichen Zhang, Pengtao Gong
    The Korean Journal of Parasitology.2017; 55(6): 673.     CrossRef
  • Prevalence ofDirofilaria immitisinfection in dogs in Henan province, central China
    Shuai Wang, Nian Zhang, Zhenchao Zhang, Dong Wang, Zhijun Yao, Haizhu Zhang, Jingbo Ma, Bin Zheng, Hongbin Ren, Shiguo Liu
    Parasite.2016; 23: 43.     CrossRef
  • Molecular detection of vector-borne agents in dogs from ten provinces of China
    Da Xu, Jilei Zhang, Zhengsheng Shi, Chunlian Song, Xiaofeng Zheng, Yi Zhang, Yongqing Hao, Haiju Dong, Lanjing Wei, Heba S. El-Mahallawy, Patrick Kelly, Wenbin Xiong, Heng Wang, Jianji Li, Xinjun Zhang, Jianhong Gu, Chengming Wang
    Parasites & Vectors.2015;[Epub]     CrossRef
  • 9,941 View
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Case Report

From 2006 to 2010, hospitals in Hanoi treated 10 human patients for dirofilariasis. The worms were collected from parasitic places, and identification of the species was completed by morphology and molecular methods. Ten parasites were recovered either from the conjunctiva (n=9) or subcutaneous tissue (n=1). The parasites were 4.0-12.5 cm in length and 0.5-0.6 mm in width. Morphological observations suggested all parasites as Dirofilaria repens. Three of the 10 parasites (1 from subcutaneous tissue and 2 from eyes) were used for molecular confirmation of the species identification. A portion of the mitochondrial cox1 (461 bp) was amplified and sequenced. Nucleotide and amino acid homologies were 95% and 99-100%, respectively, when compared with D. repens (Italian origin, GenBank AJ271614; DQ358814). This is the first report of eye dirofilariasis and the second report of subcutaneous tissue dirofilariasis due to D. repens in Vietnam.

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  • Subconjunctival Granuloma Caused by Dirofilaria repens in an Indoor Dog From Thailand: A Case Report and Mitochondrial Genome Analysis
    Natthanet Sritrakoon, Pongpun Sawatwong, Kannika Siripattarapravat, Duangkamon Siludjai, Famui Mueanpai, Peera Hemarajata, Sutawee Suksin, Wissanuwat Chimnoi, Nutsuda Klinkaew, Burin Nimsuphan
    Veterinary Ophthalmology.2025;[Epub]     CrossRef
  • Zoonotic Dirofilaria sp. “hongkongensis” in subcutaneous nodules from dogs and cats, Hong Kong SAR
    Thamali Manathunga, May Tse, Livia Perles, Frederic Beugnet, Vanessa Barrs, Domenico Otranto
    Parasites & Vectors.2024;[Epub]     CrossRef
  • Distribution of dirofilariasis in Omsk region
    T. S. Ryazanova, A. V. Sverdlova, O. Yu. Starostina, A. A. Nikitin, N. Yu. Grigorova, Yu. V. Kochetkov
    Acta Biomedica Scientifica.2022; 7(3): 277.     CrossRef
  • Canine and feline vector-borne diseases of zoonotic concern in Southeast Asia
    Viet-Linh Nguyen, Filipe Dantas-Torres, Domenico Otranto
    Current Research in Parasitology & Vector-Borne Diseases.2021; 1: 100001.     CrossRef
  • High genetic diversity in theDirofilaria repensspecies complex revealed by mitochondrial genomes of feline microfilaria samples from Narathiwat, Thailand
    Esra Yilmaz, Sirichit Wongkamchai, Sabrina Ramünke, Georgios D. Koutsovoulos, Mark L. Blaxter, Sven Poppert, Roland Schaper, Georg von Samson‐Himmelstjerna, Jürgen Krücken
    Transboundary and Emerging Diseases.2019; 66(1): 389.     CrossRef
  • Subcutaneous dirofilariasis of the groin in a male due to Dirofilaria repens
    P. Xaplanteri, P. Patrikakos, F. Kolonitsiou, N. Zacharis, C. Potsios, M. Marangos, G. Zacharis
    Hellenic Journal of Surgery.2017; 89(3-4): 178.     CrossRef
  • Molecular characterization of human Dirofilaria isolates from Kerala
    Najuma Nazar, Bindu Lakshmanan, K.K. Jayavardhanan
    Indian Journal of Medical Research.2017; 146(4): 528.     CrossRef
  • First Molecular Identification of Dirofilaria repens in a Dog Blood Sample from Guanajuato, Mexico
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    Vector-Borne and Zoonotic Diseases.2016; 16(11): 734.     CrossRef
  • Nódulo subcutáneo paraciliar de origen infrecuente
    Frederic Gómez-Bertomeu, Antoni Raventós-Estellé, Domingo Bofill-Montoro, Eva González-Carballo
    Enfermedades Infecciosas y Microbiología Clínica.2015; 33(4): 268.     CrossRef
  • A Rare Human Case of <i>Dirofilaria repens</i> Infection in the Subcutaneous Posterior Thorax with Molecular Identification
    Tran Anh Le, Thuat Thang Vi, Khac Luc Nguyen, Thanh Hoa Le
    The Korean Journal of Parasitology.2015; 53(3): 329.     CrossRef
  • The First Human Case of Thelazia callipaeda Infection in Vietnam
    Nguyen Van De, Thanh Hoa Le, Jong-Yil Chai
    The Korean Journal of Parasitology.2012; 50(3): 221.     CrossRef
  • 9,509 View
  • 78 Download
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Original Article

Seasonal Prevalence of Mosquitoes, Including Vectors of Brugian Filariasis, in Southern Islands of the Republic of Korea
Hyeng-Il Cheun, Shin-Hyeong Cho, Hee-Il Lee, E-Hyun Shin, Jong-Soo Lee, Tong-Soo Kim, Won-Ja Lee
Korean J Parasitol 2011;49(1):59-64.
Published online March 18, 2011
DOI: https://doi.org/10.3347/kjp.2011.49.1.59

A survey of mosquitoes, including the vector status of Brugia malayi filariasis and their relative larval density, was conducted from 2002 to 2005 at several southern remote islands of Jeollanam-do (province), Gyeongsangnam-do, and Jeju-do, Korea, where filariasis was previously endemic. Overall, a total of 9 species belonging to 7 genera were collected. Ochlerotatus togoi (formerly known as Aedes togoi), Anopheles (Hyrcanus) group, and Culex pipiens were the predominant species captured at all areas. Oc. togoi larvae were most frequently collected at salinity levels <0.5% during June and July, with densities decreasing sharply during the rainy season in August. The most likely explanation for the eradication of filariasis in these areas is suggested to be an aggressive treatment program executed during the 1970s and the 1990s. However, high prevalence of the vector mosquitoes may constitute a potential risk for reemerging of brugian filariasis in these areas.

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    Budi Mulyaningsih, Sitti Rahmah Umniyati, Suwarno Hadisusanto, Erwin Edyansyah
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  • A multiplex PCR assay for six Aedini species, including Aedes albopictus
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    Parasites & Vectors.2021;[Epub]     CrossRef
  • Modeling the Putative Ancient Distribution of Aedes togoi (Diptera: Culicidae)
    Daniel A H Peach, Benjamin J Matthews, Konrad Fiedler
    Journal of Insect Science.2020;[Epub]     CrossRef
  • Insecticide Coated Screen Models Reduce Insect-vector Population in a Pasture Area in Ngaoundere, Cameroon
    Sevidzem Silas Lendzele, Raymond Tchawe, Zinga-Koumba Roland, Mamoudou Abdoulmoum, Ndjonka Dieudonne, Mavoungou Jacques Francois
    Trends in Applied Sciences Research.2019; 14(2): 80.     CrossRef
  • Immune responses of Aedes togoi, Anopheles paraliae and Anopheles lesteri against nocturnally subperiodic Brugia malayi microfilariae during migration from the midgut to the site of development
    Watcharatip Dedkhad, Bruce M Christensen, Lyric C Bartholomay, Deepak Joshi, Chayanit Hempolchom, Atiporn Saeung
    Parasites & Vectors.2018;[Epub]     CrossRef
  • Co-occurrence of viruses and mosquitoes at the vectors’ optimal climate range: An underestimated risk to temperate regions?
    Marcus S. C. Blagrove, Cyril Caminade, Elisabeth Waldmann, Elizabeth R. Sutton, Maya Wardeh, Matthew Baylis, Christopher M. Barker
    PLOS Neglected Tropical Diseases.2017; 11(6): e0005604.     CrossRef
  • Peripheral Blood Smear Contamination with Helicosporium Fungi Resembling Microfilaria
    Kui-Hyun Yoon
    Annals of Laboratory Medicine.2015; 35(1): 169.     CrossRef
  • Sero-surveillance of Getah Virus among Thoroughbred Horses in Korea
    Hyun-Ye Jo, Dong-Kun Yang, Ha-Hyun Kim, Sung-Suk Choi, Kyung-Suk Kang, Sun-Ju Yang, Young-Jin Yang, In-Soo Cho
    Journal of Bacteriology and Virology.2015; 45(3): 235.     CrossRef
  • Phylogeography of the Coastal Mosquito Aedes togoi across Climatic Zones: Testing an Anthropogenic Dispersal Hypothesis
    Teiji Sota, Peter Belton, Michelle Tseng, Hoi Sen Yong, Motoyoshi Mogi, Igor Mokrousov
    PLOS ONE.2015; 10(6): e0131230.     CrossRef
  • Peritrophic matrix formation and Brugia malayi microfilaria invasion of the midgut of a susceptible vector, Ochlerotatus togoi (Diptera: Culicidae)
    Narissara Jariyapan, Atiporn Saeung, Nuchpicha Intakhan, Wetpisit Chanmol, Sriwatapron Sor-suwan, Benjarat Phattanawiboon, Kritsana Taai, Wej Choochote
    Parasitology Research.2013; 112(7): 2431.     CrossRef
  • Environmental Forcing Shapes Regional House Mosquito Synchrony in a Warming Temperate Island
    Luis Fernando Chaves, Yukiko Higa, Su Hyun Lee, Ji Yeon Jeong, Sang Taek Heo, Miok Kim, Noboru Minakawa, Keun Hwa Lee
    Environmental Entomology.2013; 42(4): 605.     CrossRef
  • Surveillance and Vector Control of Lymphatic Filariasis in the Republic of Korea
    Shin Hyeong Cho, Da Won Ma, Bo Ra Koo, Hee Eun Shin, Wook Kyo Lee, Byong Suk Jeong, Chaeshin Chu, Won Ja Lee, Hyeng Il Cheun
    Osong Public Health and Research Perspectives.2012; 3(3): 145.     CrossRef
  • 9,710 View
  • 66 Download
  • Crossref

Case Report

Orbital Dirofilariasis in Iran: A Case Report
Sepideh Tavakolizadeh, Iraj Mobedi
Korean J Parasitol 2009;47(4):397-399.
Published online December 1, 2009
DOI: https://doi.org/10.3347/kjp.2009.47.4.397

Dirofilariasis is a common parasitic disease in both domestic and wild animals around the world, with canines as the principal reservoir host and mosquitoes as the vector. Human ophthalmic dirofilariasis is an uncommon condition, but there have been reports from many parts of the world, including Africa, Australia, the Americas, Europe, and Asia. Ophthalmic involvement with Dirofilaria may present itself as periorbital, subconjunctival, orbital, or intraocular infections. In this report, we present a case of orbital dirofilariasis with lateral rectus muscle involvement. To our knowledge, this is the first orbital dirofilariasis case reported in Iran. Although debulking of the tumor usually leads to resolution, our patient showed an episode of recurrence after biopsy. Complete recovery was achieved after a spontaneous discharge, without the need for systemic medication.

Citations

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  • Human dirofilariasis – A potentially significant nematode zoonosis in an era of climate change
    Stefan Momčilović, Andriana Jovanović, Robin B. Gasser
    Journal of Infection.2025; 90(4): 106460.     CrossRef
  • Periorbital dirofilariasis: clinical profile and role of ultrasonography in its diagnosis
    Aparna K S, Abraham Kurian, Anju Suresh
    Orbit.2025; 44(6): 723.     CrossRef
  • Subconjunctival dirofilariasis in a healthy subject: a case report
    Amirhossein Aghajani, Mohammad Taher Rajabi, Seyed Mohsen Rafizadeh, Elham Rahmanikhah, Reza Samiee, Mohammad Reza Abdol Homayuni, Amin Zand
    Journal of Ophthalmic Inflammation and Infection.2024;[Epub]     CrossRef
  • Dirofilariasis Presenting as Orbital Abscess Complicating Ethmoid Sinusitis
    Vinod Felix, Lakshmi Anilkumar, Muhammed Niyas, Asgar Abbas, Kalpana Elizabeth John, Shalini R. Varma, Jyothi Chakkikavil
    Indian Journal of Otolaryngology and Head & Neck Surgery.2023; 75(4): 3636.     CrossRef
  • Human Dirofilariasis Caused by Dirofilaria repens in Sri Lanka from 1962 to 2020
    Thivya Balendran, Lalani Yatawara, Susiji Wickramasinghe
    Acta Parasitologica.2022; 67(2): 628.     CrossRef
  • Prevalence and molecular characterization of Dirofilaria immitis in road killed canids of northern Iran
    Meysam Sharifdini, Mahan Karimi, Keyhan Ashrafi, Mostafa Soleimani, Hamed Mirjalali
    BMC Veterinary Research.2022;[Epub]     CrossRef
  • Orbital Dirofilariasis Masquerading As Orbital Rhabdomyosarcoma
    Farzad Pakdel, Hadi Ghadimi, Zohreh Nozarian, Fahimeh Asadi Amoli, Niloofar Pirmarzdashti, Morteza Karimi, Mohamad Mehrpour
    Journal of Ophthalmic and Vision Research.2022; 17(4): 587.     CrossRef
  • Lymphatic filariasis in Asia: a systematic review and meta-analysis
    Negar Bizhani, Saeideh Hashemi Hafshejani, Neda Mohammadi, Mehdi Rezaei, Mohammad Bagher Rokni
    Parasitology Research.2021; 120(2): 411.     CrossRef
  • Review ofDirofilariaspp. infection in humans and animals in Iran
    Faham Khamesipour, Saeed Nezaratizade, Bahareh Basirpour, Bahareh Chelgerdi Dehkordi, Sana Sadat Afzal, Parya Kheyri, Shadan Shojaat, Sakineh Akbari, Seyed Hossein Hejazi
    Research in Veterinary Science and Medicine.2021; 1: 5.     CrossRef
  • Filarial worms: a systematic review and meta-analysis of diversity in animals from Iran with emphasis on human cases
    Ezatollah Ghasemi, Sadegh Shamsinia, Ali Taghipour, Davood Anvari, Saeed Bahadory, Seyyed Ali Shariatzadeh, Bahareh Kordi, Hamidreza Majidiani, Hassan Borji, MohammadReza Chaechi Nosrati, Ali Yousefi, Morteza Shams
    Parasitology.2020; 147(9): 909.     CrossRef
  • Molecular characterization of ocular dirofilariasis: a case report of Dirofilaria immitis in south-eastern Iran
    Razieh Parsa, Ali Sedighi, Iraj Sharifi, Mehdi Bamorovat, Saeid Nasibi
    BMC Infectious Diseases.2020;[Epub]     CrossRef
  • Application of Dirofilaria immitis immunoreactive proteins in serodiagnosis
    Majid Khanmohammadi, Reza Falak, Ahmad Reza Meamar, Elham Razmjou, Kobra Mokhtarian, Mehdi Arshadi, Nasrin Shayanfar, Lame Akhlaghi
    Parasite Immunology.2019;[Epub]     CrossRef
  • A detailed review of the mosquitoes (Diptera: Culicidae) of Iran and their medical and veterinary importance
    Shahyad Azari-Hamidian, Behzad Norouzi, Ralph E. Harbach
    Acta Tropica.2019; 194: 106.     CrossRef
  • Ocular parasitoses: A comprehensive review
    Tapas Ranjan Padhi, Sujata Das, Savitri Sharma, Soveeta Rath, Suryasnata Rath, Devjyoti Tripathy, Krushna Gopal Panda, Soumyava Basu, Cagri G. Besirli
    Survey of Ophthalmology.2017; 62(2): 161.     CrossRef
  • Ocular dirofilariasis by Dirofilaria immitis in a child in Iran: A case report and review of the literature
    Hadi Mirahmadi, Alireza Maleki, Raheleh Hasanzadeh, Mohammad Bagher Ahoo, Iraj Mobedi, Ali Rostami
    Parasitology International.2017; 66(1): 978.     CrossRef
  • The Complexity of Zoonotic Filariasis Episystem and Its Consequences: A Multidisciplinary View
    Fernando Simón, Javier González-Miguel, Alicia Diosdado, Paula Josefina Gómez, Rodrigo Morchón, Vladimir Kartashev
    BioMed Research International.2017; 2017: 1.     CrossRef
  • An unusual presentation of lacrimal gland dirofilariasis
    Amit Sethi, Vani Puri, Natasha Dogra
    Indian Journal of Ophthalmology.2017; 65(7): 615.     CrossRef
  • Periocular dirofilariasis: A case series
    Sunayana Bhat, May Saldanha, Norman Mendonca
    Orbit.2016; 35(2): 100.     CrossRef
  • A rapidly emerging ocular zoonosis; Dirofilaria repens
    I Kutlutürk, G Z S Tamer, L Karabaş, A N Erbesler, S Yazar
    Eye.2016; 30(4): 639.     CrossRef
  • Parasitic Infections of the External Eye
    Shivani Pahuja, Charuta Puranik, Bechir Jelliti, Moncef Khairallah, Virender S. Sangwan
    Ocular Immunology and Inflammation.2013; 21(4): 292.     CrossRef
  • Ocular Parasitoses and Their Immunology
    Suggerappa Laxmanappa Hoti, Veena Tandon
    Ocular Immunology and Inflammation.2011; 19(6): 385.     CrossRef
  • 9,664 View
  • 101 Download
  • Crossref

Mini Review

Successful Control of Lymphatic Filariasis in the Republic of Korea
Hyeng-Il Cheun, Yoon Kong, Shin-Hyeong Cho, Jong-Soo Lee, Jong-Yil Chai, Joo-Shil Lee, Jong-Koo Lee, Tong-Soo Kim
Korean J Parasitol 2009;47(4):323-335.
Published online December 1, 2009
DOI: https://doi.org/10.3347/kjp.2009.47.4.323

A successful experience of lymphatic filariasis control in the Republic of Korea is briefly reviewed. Filariasis in the Republic of Korea was exclusively caused by infection with Brugia malayi. Over the past several decades from the 1950s to 2006, many investigators exerted their efforts to detection, treatment, and follow-up of filariasis patients in endemic areas, and to control filariasis. Mass, combined with selective, treatments with diethylcarbamazine to microfilaria positive persons had been made them free from microfilaremia and contributed to significant decrease of the microfilarial density in previously endemic areas. Significant decrease of microfilaria positive cases in an area influenced eventually to the endemicity of filariasis in the relevant locality. Together with remarkable economic growth followed by improvement of environmental and personal hygiene and living standards, the factors stated above have contributed to blocking the transmission cycle of B. malayi and led to disappearance of this mosquito-borne ancient disease in the Republic of Korea.

Citations

Citations to this article as recorded by  Crossref logo
  • Current Status and a Perspective of Mosquito-Borne Diseases in the Republic of Korea
    Jae Hyoung Im, Tong-Soo Kim, Moon-Hyun Chung, Ji Hyeon Baek, Hea Yoon Kwon, Jin-Soo Lee
    Vector-Borne and Zoonotic Diseases.2021; 21(2): 69.     CrossRef
  • Lymphatic filariasis in Asia: a systematic review and meta-analysis
    Negar Bizhani, Saeideh Hashemi Hafshejani, Neda Mohammadi, Mehdi Rezaei, Mohammad Bagher Rokni
    Parasitology Research.2021; 120(2): 411.     CrossRef
  • The global distribution of lymphatic filariasis, 2000–18: a geospatial analysis
    Elizabeth A Cromwell, Chris A Schmidt, Kevin T Kwong, David M Pigott, Denise Mupfasoni, Gautam Biswas, Shreya Shirude, Elex Hill, Katie M Donkers, Amir Abdoli, Michael R M Abrigo, Victor Adekanmbi, Olatunji O Adetokunboh Sr., Srividya Adinarayanan, Ehsan
    The Lancet Global Health.2020; 8(9): e1186.     CrossRef
  • Progress in the elimination of lymphatic filariasis in the Western Pacific Region: successes and challenges
    Aya Yajima, Kazuyo Ichimori
    International Health.2020; 13(Supplement): S10.     CrossRef
  • Prevention and Control Strategies for Parasitic Infections in the Korea Centers for Disease Control and Prevention
    Young Yil Bahk, Eun-Hee Shin, Shin-Hyeong Cho, Jung-Won Ju, Jong-Yil Chai, Tong-Soo Kim
    The Korean Journal of Parasitology.2018; 56(5): 401.     CrossRef
  • Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis
    Ghaith Aljayyoussi, Hayley E. Tyrer, Louise Ford, Hanna Sjoberg, Nicolas Pionnier, David Waterhouse, Jill Davies, Joanne Gamble, Haelly Metuge, Darren A. N. Cook, Andrew Steven, Raman Sharma, Ana F. Guimaraes, Rachel H. Clare, Andrew Cassidy, Kelly L. Joh
    Scientific Reports.2017;[Epub]     CrossRef
  • Follow-up Study of Patients Previously Diagnosed with Lymphatic Filariasis in Korea
    Hyeng Il Cheun, Hee Eun Shin, Da Won Ma, Sung Hee Hong, Tae Yun Kim, Sang Eun Lee, JungWon Ju, Yun-Kyu Park, Tong-Soo Kim, Shin Hyeong Cho
    Osong Public Health and Research Perspectives.2017; 8(6): 421.     CrossRef
  • Impact of vectorborne parasitic neglected tropical diseases on child health
    Meagan A Barry, Kristy O Murray, Peter J Hotez, Kathryn M Jones
    Archives of Disease in Childhood.2016; 101(7): 640.     CrossRef
  • Peripheral Blood Smear Contamination with Helicosporium Fungi Resembling Microfilaria
    Kui-Hyun Yoon
    Annals of Laboratory Medicine.2015; 35(1): 169.     CrossRef
  • Seroepidemiology of Toxocariasis and Its Clinical Implications in Gwangju and Jeonnam-province, Korea
    Eun Jeong Won, Jin Kim, Myung-Geun Shin, Jong Hee Shin, Soon Pal Suh, Dong Wook Ryang
    Annals of Laboratory Medicine.2015; 35(4): 449.     CrossRef
  • Elimination of Lymphatic Filariasis
    EISAKU KIMURA
    Juntendo Medical Journal.2015; 61(4): 378.     CrossRef
  • Human Taeniasis in the Republic of Korea: Hidden or Gone?
    Jong-Yil Chai
    The Korean Journal of Parasitology.2013; 51(1): 9.     CrossRef
  • Surveillance and Vector Control of Lymphatic Filariasis in the Republic of Korea
    Shin Hyeong Cho, Da Won Ma, Bo Ra Koo, Hee Eun Shin, Wook Kyo Lee, Byong Suk Jeong, Chaeshin Chu, Won Ja Lee, Hyeng Il Cheun
    Osong Public Health and Research Perspectives.2012; 3(3): 145.     CrossRef
  • A Research Agenda for Helminth Diseases of Humans: The Problem of Helminthiases
    Sara Lustigman, Roger K. Prichard, Andrea Gazzinelli, Warwick N. Grant, Boakye A. Boatin, James S. McCarthy, María-Gloria Basáñez, Charles D. Mackenzie
    PLoS Neglected Tropical Diseases.2012; 6(4): e1582.     CrossRef
  • Recent Advances in the Use of Anthelmintics for Treating Nematode Infections
    Jong-Yil Chai
    Infection and Chemotherapy.2011; 43(1): 26.     CrossRef
  • Changing Patterns of Human Parasitic Infection in Korea
    Myoung-Hee Ahn
    Hanyang Medical Reviews.2010; 30(3): 149.     CrossRef
  • Control of neglected tropical diseases needs a long-term commitment
    Yaobi Zhang, Chad MacArthur, Likezo Mubila, Shawn Baker
    BMC Medicine.2010;[Epub]     CrossRef
  • 12,567 View
  • 111 Download
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Case Reports

Disseminated Microfilaremia Associated with Lung Cyst and Empyema: An Autopsy Report
Kirti Gupta, Uma Nahar Saikia, Prateek Bhatia, Mandeep Garg, Ajay Wanchu
Korean J Parasitol 2009;47(1):49-52.
Published online March 12, 2009
DOI: https://doi.org/10.3347/kjp.2009.47.1.49

Clinical manifestations of extralymphatic disease caused by filariasis are varied and range from symptoms due to tropical pulmonary eosinophilia to hematuria, proteinuria, splenomegaly, and rarely arthritis. Disseminated microfilaremia in association with loculated lung cyst and empyema is of rare occurrence and to the best of our knowledge has not been documented in the literature so far. We report here a case of disseminated microfilaremia due to Wuchereria bancrofti infection accompanied by a lung cyst and empyema in a 21-year-old Indian man.

Citations

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  • Immunopathological response of leukocytes against microfilariae and adult worms in white rats infected with Setaria cervi
    Sharba Kausar, Wajihullah Khan
    Veterinary World.2017; 10(5): 562.     CrossRef
  • Sudden Death Due to Coronary Blockade by Microfilaremia
    Rajpal Singh Punia, Reetu Kundu, Dasari Harish
    American Journal of Forensic Medicine & Pathology.2016; 37(4): 231.     CrossRef
  • 8,049 View
  • 72 Download
  • Crossref
Periocular Dirofilariasis in a Young Woman: A Case Report
Amir Jamshidi, Mahin Jamshidi, Iraj Mobedi, Mandana Khosroara
Korean J Parasitol 2008;46(4):265-267.
Published online December 20, 2008
DOI: https://doi.org/10.3347/kjp.2008.46.4.265

A case of periocular dirofilariasis has been diagnosed in Iran. A 27-yr old female referred with a history of edema and redness in the left eye since 2 wk ago. On slit lamp examination, a moving thread-like worm was seen in the subconjunctival area. Two days later, a 126 mm long, live filaria worm was extracted from the lower lid subcutaneous tissue. The worm was diagnosed as, likelihood, Dirofilaria immitis on microscopic examinations. The present case suggests that D. immitis can cause periocular infections.

Citations

Citations to this article as recorded by  Crossref logo
  • Prevalence and molecular characterization of Dirofilaria immitis in road killed canids of northern Iran
    Meysam Sharifdini, Mahan Karimi, Keyhan Ashrafi, Mostafa Soleimani, Hamed Mirjalali
    BMC Veterinary Research.2022;[Epub]     CrossRef
  • Polymerase chain reaction: A novel way to detect ocular dirofilariasis
    Arkaprava Pradhan, Muthusamy Raman, Jyotirmay Biswas
    Indian Journal of Ophthalmology.2022; 70(7): 2620.     CrossRef
  • Orbital Dirofilariasis Masquerading As Orbital Rhabdomyosarcoma
    Farzad Pakdel, Hadi Ghadimi, Zohreh Nozarian, Fahimeh Asadi Amoli, Niloofar Pirmarzdashti, Morteza Karimi, Mohamad Mehrpour
    Journal of Ophthalmic and Vision Research.2022; 17(4): 587.     CrossRef
  • Lymphatic filariasis in Asia: a systematic review and meta-analysis
    Negar Bizhani, Saeideh Hashemi Hafshejani, Neda Mohammadi, Mehdi Rezaei, Mohammad Bagher Rokni
    Parasitology Research.2021; 120(2): 411.     CrossRef
  • Review ofDirofilariaspp. infection in humans and animals in Iran
    Faham Khamesipour, Saeed Nezaratizade, Bahareh Basirpour, Bahareh Chelgerdi Dehkordi, Sana Sadat Afzal, Parya Kheyri, Shadan Shojaat, Sakineh Akbari, Seyed Hossein Hejazi
    Research in Veterinary Science and Medicine.2021; 1: 5.     CrossRef
  • Filarial worms: a systematic review and meta-analysis of diversity in animals from Iran with emphasis on human cases
    Ezatollah Ghasemi, Sadegh Shamsinia, Ali Taghipour, Davood Anvari, Saeed Bahadory, Seyyed Ali Shariatzadeh, Bahareh Kordi, Hamidreza Majidiani, Hassan Borji, MohammadReza Chaechi Nosrati, Ali Yousefi, Morteza Shams
    Parasitology.2020; 147(9): 909.     CrossRef
  • Molecular characterization of ocular dirofilariasis: a case report of Dirofilaria immitis in south-eastern Iran
    Razieh Parsa, Ali Sedighi, Iraj Sharifi, Mehdi Bamorovat, Saeid Nasibi
    BMC Infectious Diseases.2020;[Epub]     CrossRef
  • Application of Dirofilaria immitis immunoreactive proteins in serodiagnosis
    Majid Khanmohammadi, Reza Falak, Ahmad Reza Meamar, Elham Razmjou, Kobra Mokhtarian, Mehdi Arshadi, Nasrin Shayanfar, Lame Akhlaghi
    Parasite Immunology.2019;[Epub]     CrossRef
  • A detailed review of the mosquitoes (Diptera: Culicidae) of Iran and their medical and veterinary importance
    Shahyad Azari-Hamidian, Behzad Norouzi, Ralph E. Harbach
    Acta Tropica.2019; 194: 106.     CrossRef
  • Ocular dirofilariasis by Dirofilaria immitis in a child in Iran: A case report and review of the literature
    Hadi Mirahmadi, Alireza Maleki, Raheleh Hasanzadeh, Mohammad Bagher Ahoo, Iraj Mobedi, Ali Rostami
    Parasitology International.2017; 66(1): 978.     CrossRef
  • Human ocular onchocerciasis caused byOnchocerca lupi(Spirurida, Onchocercidae) in Iran
    G. Mowlavi, F. Farzbod, A. Kheirkhah, I. Mobedi, D.D. Bowman, S.R. Naddaf
    Journal of Helminthology.2014; 88(2): 250.     CrossRef
  • Zoonotic helminths affecting the human eye
    Domenico Otranto, Mark L Eberhard
    Parasites & Vectors.2011;[Epub]     CrossRef
  • Seroprevalence of canine heartworm disease in Kerman, southeastern Iran
    Baharak Akhtardanesh, Mohammad Hossein Radfar, Darioush Voosough, Nasim Darijani
    Comparative Clinical Pathology.2011; 20(6): 573.     CrossRef
  • A case of Dirofilaria immitis presenting as an intramuscular soft tissue mass
    S. Teerthanath, S. Hariprasad
    Indian Journal of Pathology and Microbiology.2011; 54(2): 428.     CrossRef
  • Orbital Dirofilariasis in Iran: A Case Report
    Sepideh Tavakolizadeh, Iraj Mobedi
    The Korean Journal of Parasitology.2009; 47(4): 397.     CrossRef
  • 10,935 View
  • 113 Download
  • Crossref
Ectopic Migration of an Adult Heartworm in a Dog with Dirofilariasis
Hyun-Wook Oh, Hyung-Kyou Jun, Myung-Jo You, Mineo Hayasaki, Kun-Ho Song
Korean J Parasitol 2008;46(3):171-173.
Published online September 20, 2008
DOI: https://doi.org/10.3347/kjp.2008.46.3.171

A 3-yr-old female mongrel dog was referred to the Veterinary Teaching Hospital of Chungnam National University in the Republic of Korea. An adult heartworm, Dirofilaria immitis, was found in the abdominal cavity of the dog during spaying. Dirofilariasis in this dog was also diagnosed by modified Knott's test, ELISA test, and PCR analysis. The present case is the first report on the migration of an adult dog heartworm to the abdominal cavity of a dog in the Republic of Korea.

Citations

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  • Subcutaneous dirofilariasis due to Dirofilaria immitis in a dog in Brazil: first report
    Welitânia Inácia da Silva, Alexander Rodrigo Dantas Gomes, Maria Carolina de Francisco, Janete Madalena da Silva, Hodias Sousa de Oliveira Filho, Thais Ferreira Feitosa, Vinícius Longo Ribeiro Vilela
    Revista Brasileira de Parasitologia Veterinária.2023;[Epub]     CrossRef
  • Two cases of ectopic dirofilariasis by Dirofilaria immitis in subconjunctival and subcutaneous tissues in dogs
    Yeong-Seok Goh, Hye-Min Kim, Badriah Alkathiri, Hong Suh Chang, Young Min Yoon, Seung-Hun Lee, Kyung-Mee Park
    Parasitology International.2023; 92: 102683.     CrossRef
  • Incidental Finding of Dirofilaria immitis (Spirurida: Onchocercidae) Microfilariae in the Bone Marrow of a Dog with Mixed Leishmania infantum-Dirofilaria immitis Infection
    Ilaria Lensi, George Lubas, Roberto Amerigo Papini
    Zoonotic Diseases.2023; 3(2): 162.     CrossRef
  • Distribution of dirofilariasis in Omsk region
    T. S. Ryazanova, A. V. Sverdlova, O. Yu. Starostina, A. A. Nikitin, N. Yu. Grigorova, Yu. V. Kochetkov
    Acta Biomedica Scientifica.2022; 7(3): 277.     CrossRef
  • Prevalence of Dirofilaria immitis in shelter dogs in Bucaramanga metropolitan area, Colombia
    Angel Alberto Florez Muñoz, Ariel Rosas Martinez, Juan Carlos Pinilla
    Veterinary Parasitology: Regional Studies and Reports.2020; 22: 100489.     CrossRef
  • Dracunculus infections in domestic dogs and cats in North America; an under-recognized parasite?
    Brianna M. Williams, Christopher A. Cleveland, Guilherme G. Verocai, Liandrie Swanepoel, Kevin D. Niedringhaus, Kelsey L. Paras, Yoko Nagamori, Susan E. Little, Andrea Varela-Stokes, Nicole Nemeth, Heidi Wyrosdick, Alison Tucker, Leigh Deal, Dawn Gauthier
    Veterinary Parasitology: Regional Studies and Reports.2018; 13: 148.     CrossRef
  • Aberrant peritoneal localization of Dirofilaria repens in a dog
    Marco Pierantozzi, Giada Di Giulio, Donato Traversa, Giovanni Aste, Angela Di Cesare
    Veterinary Parasitology: Regional Studies and Reports.2017; 10: 62.     CrossRef
  • A combined human case of Dirofilaria ursi infection in dorsal subcutaneous tissue and Anisakis simplex sensu stricto (s.s.) infection in ventral subcutaneous tissue
    Minoru Yamada, Namiko Shishito, Yoshihiro Nozawa, Shigehiko Uni, Keisuke Nishioka, Takaaki Nakaya
    Tropical Medicine and Health.2017;[Epub]     CrossRef
  • Aberrant migration of Dirofilaria immitis in the peritoneum of a dog
    Courtenay Brines, Prince Agbedanu, Rachel Juelsgaard, Steve Carlson, Matthew Brewer
    Veterinary Record Case Reports.2016;[Epub]     CrossRef
  • Bilateral femoral arterial dirofilariasis caused by Dirofilaria immitis in a dog
    David A Upchurch, Daniel M Ogden, David G Baker
    Veterinary Record Case Reports.2015;[Epub]     CrossRef
  • Retrospective study of canine heartworm disease with caval syndrome in Grenada, West Indies
    A. Chikweto, M.I. Bhaiyat, M. Lanza-Perea, S. Veytsman, K. Tiwari, C. De Allie, R.N. Sharma
    Veterinary Parasitology.2014; 205(3-4): 721.     CrossRef
  • Vector-borne helminths of dogs and humans in Europe
    Domenico Otranto, Filipe Dantas-Torres, Emanuele Brianti, Donato Traversa, Dusan Petrić, Claudio Genchi, Gioia Capelli
    Parasites & Vectors.2013;[Epub]     CrossRef
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Mini Review

Clinical and Pathological Aspects of Filarial Lymphedema and Its Management
R. K. Shenoy
Korean J Parasitol 2008;46(3):119-125.
Published online September 20, 2008
DOI: https://doi.org/10.3347/kjp.2008.46.3.119

Lymphatic filariasis, transmitted by mosquitoes is the commonest cause of lymphedema in endemic countries. Among 120 million infected people in 83 countries, up to 16 million have lymphedema. Microfilariae ingested by mosquitoes grow into infective larvae. These larvae entering humans after infected mosquito bites grow in the lymphatics to adult worms that cause damage to lymphatics resulting in dilatation of lymph vessels. This earliest pathology is demonstrated in adults as well as in children, by ultrasonography, lymphoscintigraphy and histopathology studies. Once established, this damage was thought to be irreversible. This lymphatic damage predisposes to bacterial infection that causes recurrent acute attacks of dermato-lymphangio-adenitis in the affected limbs. Bacteria, mainly streptococci gain entry into the lymphatics through 'entry lesions' in skin, like interdigital fungal infections, injuries, eczema or similar causes that disrupt integrity of skin. Attacks of dermato-lymphangio-adenitis aggravates lymphatic damage causing lymphedema, which gets worse with repeated acute attacks. Elephantiasis is a late manifestation of lymphatic filariasis, which apart from limbs may involve genitalia or breasts. Lymphedema management includes use of antifilarial drugs in early stages, treatment and prevention of acute attacks through 'limb-hygiene', antibiotics and antifungals where indicated, and physical measures to reduce the swelling. In selected cases surgery is helpful.

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    Scientific Reports.2024;[Epub]     CrossRef
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    Adam M. Fimbo, Rajabu Hussein Mnkugwe, Eulambius Mathias Mlugu, Peter P. Kunambi, Alpha Malishee, Omary M.S. Minzi, Appolinary A. R. Kamuhabwa, Eleni Aklillu
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    Amrita Journal of Medicine.2024; 20(4): 172.     CrossRef
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    Environmental Pollution.2021; 289: 117818.     CrossRef
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    BMJ Case Reports.2021; 14(11): e245036.     CrossRef
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    BMJ Case Reports.2021; 14(11): e244721.     CrossRef
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    Tropical Medicine and Health.2020;[Epub]     CrossRef
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    Journal of Helminthology.2019; 93(05): 519.     CrossRef
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    BMJ.2019; : k5198.     CrossRef
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    Cellular Immunology.2019; 341: 103927.     CrossRef
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    Asian Pacific Journal of Tropical Disease.2014; 4: S186.     CrossRef
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    Circulation Research.2014; 114(1): 56.     CrossRef
  • Lymphatic Filariasis: Perspectives on Lymphatic Remodeling and Contractile Dysfunction in Filarial Disease Pathogenesis
    Sanjukta Chakraborty, Manokaran Gurusamy, David C. Zawieja, Mariappan Muthuchamy
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Original Article

A serological survey of Dirofilaria immitis infection in pet dogs of Busan, Korea, and effects of chemoprophylaxis
Kang Hyun Byeon, Bong Jin Kim, Sun-Mi Kim, Hak Sun Yu, Hae Jin Jeong, Mee-Sun Ock
Korean J Parasitol 2007;45(1):27-32.
Published online March 20, 2007
DOI: https://doi.org/10.3347/kjp.2007.45.1.27

The status of Dirofilaria immitis infection was assessed in pet dogs of Busan, Korea, and chemoprophylactic effects of microfilaricidal medication were evaluated. A total of 294 pet dogs older than 6 mo were examined, 217 of which had been maintained indoors, and 77 had been kept outdoors. The SnapR kit and direct microscopic examinations of the peripheral blood were used. The mean overall parasite positive rates were 10.2% and 6.5%, respectively. Outdoor dogs evidenced adult worm infection rate of 31.2% and microfilaria infection rate of 18.2%. The indoor dogs, however, evidenced adult worm infection rate of 2.8% and microfilaria infection rate of 2.3%. The prevalence in males was more than 2 times that of females. The changing pattern of infection rates by age evidenced a gradual increase, from 2- to 6-year-old dogs, after which, a decrease in infection rates was noted. With regard to chemoprophylaxis, the infection rates of complete and incomplete chemoprophylaxis groups were found to be 2-3 times lower than that of the non-chemoprophylaxis group. The results of the present study indicate that the risk of exposure to D. immitis in pet dogs is quite high, particularly in male outdoor dogs, and chemoprophylactic measures were quite effective.

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    Parasitology Research.2023; 122(2): 461.     CrossRef
  • Molecular detection of Dirofilaria immitis and its Wolbachia endosymbionts in dogs from Myanmar
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  • Detection of Dirofilaria immitis using microscopic, serological and molecular techniques among dogs in Cabo Frio, RJ, Brazil
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    Revista Brasileira de Parasitologia Veterinária.2020;[Epub]     CrossRef
  • The global status of Dirofilaria immitis in dogs: a systematic review and meta-analysis based on published articles
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    Research in Veterinary Science.2020; 131: 104.     CrossRef
  • Prevalence of dirofilariasis in shepherd and stray dogs in Iranshahr, southeast of Iran
    Davood Anvari, Dariush Saadati, Abolghasem Siyadatpanah, Shirzad Gholami
    Journal of Parasitic Diseases.2019; 43(2): 319.     CrossRef
  • Molecular Analysis of Canine Filaria and Its Wolbachia Endosymbionts in Domestic Dogs Collected from Two Animal University Hospitals in Bangkok Metropolitan Region, Thailand
    Hathaithip Satjawongvanit, Atchara Phumee, Sonthaya Tiawsirisup, Sivapong Sungpradit, Narisa Brownell, Padet Siriyasatien, Kanok Preativatanyou
    Pathogens.2019; 8(3): 114.     CrossRef
  • Incidence of Dirofilaria immitis in dogs presented at University of Nigeria, Nsukka Veterinary Teaching Hospital using wet smear and buffy coat techniques
    Chukwuebuka Iniobong Ikenna Ugochukwu, Nebolisah Omekam, Emmanuel Ikenna Ugochukwu
    Asian Pacific Journal of Tropical Disease.2016; 6(8): 627.     CrossRef
  • Prevalence ofDirofilaria immitisinfection in dogs in Henan province, central China
    Shuai Wang, Nian Zhang, Zhenchao Zhang, Dong Wang, Zhijun Yao, Haizhu Zhang, Jingbo Ma, Bin Zheng, Hongbin Ren, Shiguo Liu
    Parasite.2016; 23: 43.     CrossRef
  • Epidemiological aspects of Dirofilaria immitis infection in dogs from Assam of Northeast India
    Kanta Bhattacharjee, Prabhat Chandra Sarmah
    Asian Pacific Journal of Tropical Disease.2014; 4: S255.     CrossRef
  • Microscopic, serologic and molecular surveys on Dirofilaria immitis in stray dogs, Turkey
    Sami Simsek, Yunusemre Ozkanlar, Ibrahim Balkaya, Mustafa Sinan Aktas
    Veterinary Parasitology.2011; 183(1-2): 109.     CrossRef
  • Public health issues concerning the widespread distribution of canine heartworm disease
    Alice C.Y. Lee, Susan P. Montgomery, Jerold H. Theis, Byron L. Blagburn, Mark L. Eberhard
    Trends in Parasitology.2010; 26(4): 168.     CrossRef
  • Comparison of selected canine vector-borne diseases between urban animal shelter and rural hunting dogs in Korea
    Sun Lim, Peter J Irwin, SeungRyong Lee, MyungHwan Oh, KyuSung Ahn, BoYoung Myung, SungShik Shin
    Parasites & Vectors.2010;[Epub]     CrossRef
  • Serological and molecular studies onDirofilaria immitisin dogs from Turkey
    S. Simsek, A.E. Utuk, E. Koroglu, M. Rishniw
    Journal of Helminthology.2008; 82(2): 181.     CrossRef
  • Ectopic Migration of an Adult Heartworm in a Dog with Dirofilariasis
    Hyun-Wook Oh, Hyung-Kyou Jun, Myung-Jo You, Mineo Hayasaki, Kun-Ho Song
    The Korean Journal of Parasitology.2008; 46(3): 171.     CrossRef
  • 8,338 View
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Brief Communications

The intestines and hearts of dogs were examined for Toxocara canis, Toxascaris leonina, and Dirofilaria immitis, after necropsy between June 26 and September 29, 2004 in Chuncheon, Korea. Of the 662 dogs examined, 6 were infected with T. canis (0.9%), 86 with T. leonina (13.0%). Fifty dogs were infected with D. immitis among 500 dogs examined (10.0%). Five were co-infected with T. canis and T. leonina, and three were co-infected with T. leonina and D. immitis. The cumulative positive infection rate for three species was 134/662(20.2%). Considering previously reported seropositive rates of T. canis excretory-secretory antigen, i.e., 5% in the adult population in Korea, the possibility of toxocariasis caused by T. leonina should be reevaluated.

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    Research in Veterinary Science.2020; 131: 104.     CrossRef
  • In vitro study of disinfectants on the embryonation and survival of Toxascaris leonina eggs
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    Journal of Helminthology.2018; 92(5): 530.     CrossRef
  • Clinical course and treatment outcomes of toxocariasis-related eosinophilic disorder
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    Medicine.2018; 97(37): e12361.     CrossRef
  • Neurotoxocariasis: a systematic literature review
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  • Role of Pet Dogs in Transmitting Zoonotic Intestinal Parasites in Egypt
    M.A. Ibrahim, K.A. Gihan, S.M. Aboelhadid, M.M. Abdel-Rahi
    Asian Journal of Animal and Veterinary Advances.2016; 11(6): 341.     CrossRef
  • Cross-reactivity of Toxocariasis with Crude Antigen ofToxascaris leoninaLarvae by ELISA
    Yan Jin, Chenghua Shen, Sun Huh, Min-Ho Choi, Sung-Tae Hong
    Journal of Korean Medical Science.2015; 30(5): 549.     CrossRef
  • Significance of Serum Antibody Test for Toxocariasis in Healthy Healthcare Examinees with Eosinophilia in Seoul and Gyeongsangnam-do, Korea
    Hong Seok Kim, Yan Jin, Min-Ho Choi, Jae-Hwan Kim, Young Ha Lee, Cheong Ha Yoon, Eui-Hyuk Hwang, Hun Kang, Sang-Yong Ahn, Gi Jin Kim, Sung-Tae Hong
    Journal of Korean Medical Science.2014; 29(12): 1618.     CrossRef
  • Alteration of Cytokine Production during Visceral Larva Migrans by Toxascaris leonina in Mice
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    The Korean Journal of Parasitology.2013; 51(5): 583.     CrossRef
  • A Seroepidemiological Survey of Toxocariasis among Eosinophilia Patients in Chungcheongnam-do
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    The Korean Journal of Parasitology.2012; 50(3): 249.     CrossRef
  • Seroprevalence and risk factors for canine toxocariasis by detection of specific IgG as a marker of infection in dogs from Salvador, Brazil
    Sabynne Christina Silva Regis, Lívia Ribeiro Mendonça, Nairléia dos Santos Silva, Vitor Camilo Cavalcante Dattoli, Neuza Maria Alcântara-Neves, Stella Maria Barrouin-Melo
    Acta Tropica.2011; 120(1-2): 46.     CrossRef
  • Ultrastructural Localization of Toxocara canis Larval Antigen Reacted with a Seropositive Human Serum
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    The Korean Journal of Parasitology.2009; 47(1): 65.     CrossRef
  • Seroprevalence of Toxocariasis among Healthy People with Eosinophilia
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    The Korean Journal of Parasitology.2008; 46(1): 29.     CrossRef
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A survey of Brugia malayi infection on the Heugsan Islands, Korea
Jong-Yil Chai, Soon-Hyung Lee, Sung-Yil Choi, Jong-Soo Lee, Tai-Soon Yong, Kyun-Jong Park, Kyeong-Ae Yang, Keon-Hoon Lee, Mi-Jeng Park, Hyung-Ran Park, Mi-Ja Kim, Han-Jong Rim
Korean J Parasitol 2003;41(1):69-73.
Published online March 20, 2003
DOI: https://doi.org/10.3347/kjp.2003.41.1.69

Lymphatic filariasis due to Brugia malayi infection was endemic in several areas of South Korea. The infection was controlled, or disappeared, in most areas, with the exception of the remote southwestern islands of Jeonranam-do, including the Heugsan Islands. To discover its current situation, a small-scale survey was performed on the Heugsan Islands in September 2000. A total of 378 people, 151 male and 227 female, living in 8 villages (6 on Daeheugsan-do, 1 on Daejang-do, and 1 on Yeongsan-do) were subjected to a night blood survey for microfilaremia, and physical examination for elephantiasis on the extremities. There were 6 (1.6%) microfilaria positive cases, all in females aged 57-72 years, and from only two villages of the Daeheugsan-do area. There were 4 patients with lower leg elephantiasis, but they showed no microfilaremia. The results show that a low-grade endemicity of filariasis remains on the Daeheugsan-do.

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    The Korean Journal of Parasitology.2018; 56(5): 401.     CrossRef
  • Follow-up Study of Patients Previously Diagnosed with Lymphatic Filariasis in Korea
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    Osong Public Health and Research Perspectives.2017; 8(6): 421.     CrossRef
  • Surveillance and Vector Control of Lymphatic Filariasis in the Republic of Korea
    Shin Hyeong Cho, Da Won Ma, Bo Ra Koo, Hee Eun Shin, Wook Kyo Lee, Byong Suk Jeong, Chaeshin Chu, Won Ja Lee, Hyeng Il Cheun
    Osong Public Health and Research Perspectives.2012; 3(3): 145.     CrossRef
  • Seasonal Prevalence of Mosquitoes, Including Vectors of Brugian Filariasis, in Southern Islands of the Republic of Korea
    Hyeng-Il Cheun, Shin-Hyeong Cho, Hee-Il Lee, E-Hyun Shin, Jong-Soo Lee, Tong-Soo Kim, Won-Ja Lee
    The Korean Journal of Parasitology.2011; 49(1): 59.     CrossRef
  • Elimination of lymphatic filariasis in the Republic of Korea: an epidemiological survey of formerly endemic areas, 2002–2006
    Hyeong‐Il Cheun, Jong‐Soo Lee, Shin‐Hyeong Cho, Yoon Kong, Tong‐Soo Kim
    Tropical Medicine & International Health.2009; 14(4): 445.     CrossRef
  • Review of Zoonotic Parasites in Medical and Veterinary Fields in the Republic of Korea
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    The Korean Journal of Parasitology.2009; 47(Suppl): S133.     CrossRef
  • Successful Control of Lymphatic Filariasis in the Republic of Korea
    Hyeng-Il Cheun, Yoon Kong, Shin-Hyeong Cho, Jong-Soo Lee, Jong-Yil Chai, Joo-Shil Lee, Jong-Koo Lee, Tong-Soo Kim
    The Korean Journal of Parasitology.2009; 47(4): 323.     CrossRef
  • Trends in parasitic diseases in the Republic of Korea
    Eun-Hee Shin, Sang-Mee Guk, Hyo-Jin Kim, Soon-Hyung Lee, Jong-Yil Chai
    Trends in Parasitology.2008; 24(3): 143.     CrossRef
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Cross-reactivity between sera from dogs experimentally infected with Dirofilaria immitis and crude extract of Toxocara canis
Kun-Ho Song, Mineo Hayasaki, Kyu-Woan Cho, Sang-Eun Lee, Duck-Hwan Kim
Korean J Parasitol 2002;40(4):195-198.
Published online December 30, 2002
DOI: https://doi.org/10.3347/kjp.2002.40.4.195

This study was performed to investigate whethere there is cross-reactivity between Dirofilaria immitis and three intestinal nematodes of dogs. In ELISA, D. immitis-infected dog sera obtained at the 4th molting stage (9-11 weeks) and microfilaremic stage (25-30 weeks) were shown to be highly reactive with crude extract of T. canis. In immunoblotting, some antigenic fractions, 44, 57, 88, 100 kDa of crude extract of T. canis, were found to be positive reaction with sera of dogs infected with D. immitis. However, little or no cross-reaction were observed between sera of D. immitis-infected dogs and crude extract antigen of T. vulpis or A. caninum. These result suggest that there are partial cross reaction between sera of D. immitis-infected dogs and the antigen of T. canis.

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    PLOS ONE.2018; 13(7): e0200419.     CrossRef
  • Heat treatment and false-positive heartworm antigen testing in ex vivo parasites and dogs naturally infected by Dirofilaria repens and Angiostrongylus vasorum
    Luigi Venco, Simone Manzocchi, Marco Genchi, Laura H. Kramer
    Parasites & Vectors.2017;[Epub]     CrossRef
  • Relevance of Eosinophilia and Hyper-IgE in Immigrant Children
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    Medicine.2014; 93(6): e43.     CrossRef
  • Isolation of an Antigen Fraction fromSetaria cerviAdults Having Potential for Immunodiagnosis of Human Filariasis
    Nuzhat A. Kaushal, Neelu Srivastava, Huma Mustafa, Ashish Tandon, Shravan K. Singh, Deep C. Kaushal
    Immunological Investigations.2009; 38(8): 749.     CrossRef
  • 7,517 View
  • 90 Download
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Original Article
Periodicity exhibited by Dirofilaria immitis microfilariae identified in dogs of Korea
Jae Ku Rhee, Sam Sung Yang, Hyeon Cheol Kim
Korean J Parasitol 1998;36(4):235-239.
Published online December 20, 1998
DOI: https://doi.org/10.3347/kjp.1998.36.4.235

Microfilarial periodicity of Dirofilaria immitis (the dog heartworm) was determined at two hr intervals for 72 consecutive hrs in 10 naturally infected war dogs, 3-9 years old, in Korea to facilitate harvest of the microfilariae for possible use in laboratory works and to elucidate further the periodicity of the microfilaria depending on geographic location. Although the periodicity had been observed as being low-grade nocturnal, maximal microfilarial counts were found at 21:00 hr and minimal at 11:00 hr, giving rise to an evident peak in fluctuation of the larval counts. This is the first record of the periodicity of the microfilariae identified as D. immitis in Korea.

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  • Development of a novel rodent model for dog heartworm microfilaremia using the severe-combined immunodeficiency mouse
    Mihoko Mizuseki, Nao Ikeda, Takahiro Shirozu, Maki Yamagishi, Sugao Oshiro, Shinya Fukumoto
    Scientific Reports.2024;[Epub]     CrossRef
  • The seroprevalence of canine dirofilariosis in dogs in the eastern coastal areas of China
    Dongjie Cai, Bin Tian, Yongxia Liu, Mujeeb Ur Rehman, David Ranucci, Fabrizia Veronesi, Antonio Varcasia, Wanzhong Jia, Jianzhu Liu
    Heliyon.2023; 9(6): e17009.     CrossRef
  • Updates on the distribution and host spectrum of Dirofilaria repens in the Republic of Uzbekistan
    Alisher Safarov, Firuza Akramova, Djalaliddin Azimov, Andrei D. Mihalca, Angela M. Ionică
    Parasitology Research.2021; 120(12): 3987.     CrossRef
  • Acetic acid as an alternative reagent in the modified Knott test
    Christopher C. Evans, Jenna L. Bradner, Molly D. Savadelis, C. Thomas Nelson, Andrew R. Moorhead
    Veterinary Parasitology.2019; 276: 108975.     CrossRef
  • Dirofilaria immitis and D. repens show circadian co-periodicity in naturally co-infected dogs
    Angela Monica Ionică, Ioana Adriana Matei, Gianluca D’Amico, Lucia Victoria Bel, Mirabela Oana Dumitrache, David Modrý, Andrei Daniel Mihalca
    Parasites & Vectors.2017;[Epub]     CrossRef
  • Seasonality and circadian variation of microfilaremia in dogs experimentally infected with Dirofilaria immitis
    Léonore Lovis, Mélanie Grandjean, Laurence Overney, Wolfgang Seewald, Heinz Sager
    Veterinary Parasitology.2017; 243: 235.     CrossRef
  • Dirofilaria immitis exhibits sex- and stage-specific differences in excretory/secretory miRNA and protein profiles
    Lucienne Tritten, Damian Clarke, Scott Timmins, Tom McTier, Timothy G. Geary
    Veterinary Parasitology.2016; 232: 1.     CrossRef
  • Loa loa and Onchocerca ochengi miRNAs detected in host circulation
    Lucienne Tritten, Maeghan O’Neill, Chuck Nutting, Samuel Wanji, Abdel Njouendoui, Fanny Fombad, Jonas Kengne-Ouaffo, Charles Mackenzie, Timothy Geary
    Molecular and Biochemical Parasitology.2014; 198(1): 14.     CrossRef
  • Detection of Circulating Parasite-Derived MicroRNAs in Filarial Infections
    Lucienne Tritten, Erica Burkman, Andrew Moorhead, Mohammed Satti, James Geary, Charles Mackenzie, Timothy Geary, Thomas B. Nutman
    PLoS Neglected Tropical Diseases.2014; 8(7): e2971.     CrossRef
  • Seroprevalence and Geographic Distribution ofDirofilaria immitisand Tick-Borne Infections (Anaplasma phagocytophilum,Borrelia burgdorferisensu lato, andEhrlichia canis) in Dogs from Romania
    Viorica Mircean, Mirabela Oana Dumitrache, Adriana Györke, Nikola Pantchev, Robert Jodies, Andrei Daniel Mihalca, Vasile Cozma
    Vector-Borne and Zoonotic Diseases.2012; 12(7): 595.     CrossRef
  • Prevalence of Dirofilaria immitis infection in dogs from Dandong, China
    Honglie Hou, Guoshun Shen, Wei Wu, Pengtao Gong, Quan Liu, Juan You, Yanan Cai, Jianhua Li, Xichen Zhang
    Veterinary Parasitology.2011; 183(1-2): 189.     CrossRef
  • Prevalence and epidemiological aspects of Dirofilaria immitis in dogs from Kayseri Province, Turkey
    A. Yildirim, A. Ica, O. Atalay, O. Duzlu, A. Inci
    Research in Veterinary Science.2007; 82(3): 358.     CrossRef
  • Genetic determinism of parasitic circadian periodicity and subperiodicity in human lymphatic filariasis
    Gaston Pichon, Jean-Pierre Treuil
    Comptes Rendus. Biologies.2004; 327(12): 1087.     CrossRef
  • Seroprevalence of canine dirofilariosis in South Korea
    K.H. Song, S.E. Lee, M. Hayasaki, K. Shiramizu, D.H. Kim, K.W. Cho
    Veterinary Parasitology.2003; 114(3): 231.     CrossRef
  • 8,496 View
  • 78 Download
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